메뉴 건너뛰기




Volumn 191, Issue 20, 2009, Pages 6312-6319

The uracil DNA glycosylase UdgB of Mycobacterium smegmatis protects the organism from the mutagenic effects of cytosine and adenine deamination

Author keywords

[No Author keywords available]

Indexed keywords

ADENINE; CYTOSINE; FLUOROURACIL; THYMIDYLATE SYNTHASE; URACIL DNA GLYCOSIDASE;

EID: 70350469035     PISSN: 00219193     EISSN: None     Source Type: Journal    
DOI: 10.1128/JB.00613-09     Document Type: Article
Times cited : (17)

References (40)
  • 1
    • 0019198357 scopus 로고
    • Mutagenic deamination of cytosine residues in DNA
    • Duncan, B. K., and J. H. Miller. 1980. Mutagenic deamination of cytosine residues in DNA. Nature 287:560-561.
    • (1980) Nature , vol.287 , pp. 560-561
    • Duncan, B.K.1    Miller, J.H.2
  • 2
    • 0023967987 scopus 로고
    • Lethality of a dut (deoxyuridine triphosphatase) mutation in Escherichia coli
    • el-Hajj, H. H., H. Zhang, and B. Weiss. 1988. Lethality of a dut (deoxyuridine triphosphatase) mutation in Escherichia coli. J. Bacteriol. 170:1069-1075.
    • (1988) J. Bacteriol. , vol.170 , pp. 1069-1075
    • El-Hajj, H.H.1    Zhang, H.2    Weiss, B.3
  • 3
    • 0242412184 scopus 로고    scopus 로고
    • Origin of endogenous DNA abasic sites in Saccharomyces cerevisiae
    • Guillet, M., and S. Boiteux. 2003. Origin of endogenous DNA abasic sites in Saccharomyces cerevisiae. Mol. Cell. Biol. 23:8386-8394.
    • (2003) Mol. Cell. Biol. , vol.23 , pp. 8386-8394
    • Guillet, M.1    Boiteux, S.2
  • 5
    • 0033602148 scopus 로고    scopus 로고
    • Identification of a new uracil-DNA glycosylase family by expression cloning using synthetic inhibitors
    • Haushalter, K. A., M. W. Todd Stukenberg, M. W. Kirschner, and G. L. Verdine. 1999. Identification of a new uracil-DNA glycosylase family by expression cloning using synthetic inhibitors. Curr. Biol. 9:174-185.
    • (1999) Curr. Biol. , vol.9 , pp. 174-185
    • Haushalter, K.A.1    Todd Stukenberg, M.W.2    Kirschner, M.W.3    Verdine, G.L.4
  • 8
    • 0022506923 scopus 로고
    • DNA fragmentation and cytotoxicity from increased cellular deoxyuridylate
    • Ingraham, H. A., L. Dickey, and M. Goulian. 1986. DNA fragmentation and cytotoxicity from increased cellular deoxyuridylate. Biochemistry 25:3225-3230.
    • (1986) Biochemistry , vol.25 , pp. 3225-3230
    • Ingraham, H.A.1    Dickey, L.2    Goulian, M.3
  • 9
    • 0020072369 scopus 로고
    • Nucleotide levels and incorporation of 5-fluorouracil and uracil into DNA of cells treated with 5-fluorodeoxyuridine
    • Ingraham, H. A., B. Y. Tseng, and M. Goulian. 1982. Nucleotide levels and incorporation of 5-fluorouracil and uracil into DNA of cells treated with 5-fluorodeoxyuridine. Mol. Pharmacol. 21:211-216.
    • (1982) Mol. Pharmacol. , vol.21 , pp. 211-216
    • Ingraham, H.A.1    Tseng, B.Y.2    Goulian, M.3
  • 10
    • 0030985997 scopus 로고    scopus 로고
    • Rates of spontaneous mutation in an archaeon from geothermal environments
    • Jacobs, K. L., and D. W. Grogan. 1997. Rates of spontaneous mutation in an archaeon from geothermal environments. J. Bacteriol. 179:3298-3303. (Pubitemid 27203006)
    • (1997) Journal of Bacteriology , vol.179 , Issue.10 , pp. 3298-3303
    • Jacobs, K.L.1    Grogan, D.W.2
  • 12
    • 27844555425 scopus 로고    scopus 로고
    • Physical and functional interaction of human nuclear uracil-DNA glycosylase with proliferating cell nuclear antigen
    • DOI 10.1016/j.dnarep.2005.08.006, PII S1568786405002090
    • Ko, R., and S. E. Bennett. 2005. Physical and functional interaction of human nuclear uracil-DNA glycosylase with proliferating cell nuclear antigen. DNA Repair 4:1421-1431. (Pubitemid 41655959)
    • (2005) DNA Repair , vol.4 , Issue.12 , pp. 1421-1431
    • Ko, R.1    Bennett, S.E.2
  • 13
    • 4944241573 scopus 로고    scopus 로고
    • Small interfering RNA-mediated suppression of dUTPase sensitizes cancer cell lines to thymidylate synthase inhibition
    • Koehler, S. E., and R. D. Ladner. 2004. Small interfering RNA-mediated suppression of dUTPase sensitizes cancer cell lines to thymidylate synthase inhibition. Mol. Pharmacol. 66:620-626.
    • (2004) Mol. Pharmacol. , vol.66 , pp. 620-626
    • Koehler, S.E.1    Ladner, R.D.2
  • 14
    • 28844477965 scopus 로고    scopus 로고
    • Fragmentation of replicating chromosomes triggered by uracil in DNA
    • Kouzminova, E. A., and A. Kuzminov. 2006. Fragmentation of replicating chromosomes triggered by uracil in DNA. J. Mol. Biol. 355:20-33.
    • (2006) J. Mol. Biol. , vol.355 , pp. 20-33
    • Kouzminova, E.A.1    Kuzminov, A.2
  • 15
    • 40549129679 scopus 로고    scopus 로고
    • Patterns of chromosomal fragmentation due to uracil-DNA incorporation reveal a novel mechanism of replication-dependent double-stranded breaks
    • Kouzminova, E. A., and A. Kuzminov. 2008. Patterns of chromosomal fragmentation due to uracil-DNA incorporation reveal a novel mechanism of replication-dependent double-stranded breaks. Mol. Microbiol. 68:202-215.
    • (2008) Mol. Microbiol. , vol.68 , pp. 202-215
    • Kouzminova, E.A.1    Kuzminov, A.2
  • 16
    • 0025113010 scopus 로고
    • Analysis of class II (hydrolytic) and class I (beta-lyase) apurinic/apyrimidinic endonucleases with a synthetic DNA substrate
    • Levin, J. D., and B. Demple. 1990. Analysis of class II (hydrolytic) and class I (beta-lyase) apurinic/apyrimidinic endonucleases with a synthetic DNA substrate. Nucleic Acids Res. 18:5069-5075. (Pubitemid 20270051)
    • (1990) Nucleic Acids Research , vol.18 , Issue.17 , pp. 5069-5075
    • Levin, J.D.1    Demple, B.2
  • 17
    • 0027278557 scopus 로고
    • Instability and decay of the primary structure of DNA
    • DOI 10.1038/362709a0
    • Lindahl, T. 1993. Instability and decay of the primary structure of DNA. Nature 362:709-715. (Pubitemid 23125973)
    • (1993) Nature , vol.362 , Issue.6422 , pp. 709-715
    • Lindahl, T.1
  • 18
    • 0017392934 scopus 로고
    • DNA N-glycosidases: Properties of uracil-DNA glycosidase from Escherichia coli
    • Lindahl, T., S. Ljungquist, W. Siegert, B. Nyberg, and B. Sperens. 1977. DNA N-glycosidases: properties of uracil-DNA glycosidase from Escherichia coli. J. Biol. Chem. 252:3286-3294.
    • (1977) J. Biol. Chem. , vol.252 , pp. 3286-3294
    • Lindahl, T.1    Ljungquist, S.2    Siegert, W.3    Nyberg, B.4    Sperens, B.5
  • 19
    • 0016257644 scopus 로고
    • Heat-induced deamination of cytosine residues in deoxyribonucleic acid
    • Lindahl, T., and B. Nyberg. 1974. Heat-induced deamination of cytosine residues in deoxyribonucleic acid. Biochemistry 13:3405-3410.
    • (1974) Biochemistry , vol.13 , pp. 3405-3410
    • Lindahl, T.1    Nyberg, B.2
  • 21
    • 0027383758 scopus 로고
    • The purification of a mismatch-specific thymine-DNA glycosylase from HeLa cells
    • Neddermann, P., and J. Jiricny. 1993. The purification of a mismatch-specific thymine-DNA glycosylase from HeLa cells. J. Biol. Chem. 268:21218-21224.
    • (1993) J. Biol. Chem. , vol.268 , pp. 21218-21224
    • Neddermann, P.1    Jiricny, J.2
  • 22
    • 0025769007 scopus 로고
    • Human uracil-DNA glycosylase complements E. coli ung mutants
    • Olsen, L. C., R. Aasland, H. E. Krokan, and D. E. Helland. 1991. Human uracil-DNA glycosylase complements E. coli ung mutants. Nucleic Acids Res. 19:4473-4478.
    • (1991) Nucleic Acids Res. , vol.19 , pp. 4473-4478
    • Olsen, L.C.1    Aasland, R.2    Krokan, H.E.3    Helland, D.E.4
  • 24
    • 3242882168 scopus 로고    scopus 로고
    • MyHits: A new interactive resource for protein annotation and domain identification
    • DOI 10.1093/nar/gkh479
    • Pagni, M., V. Ioannidis, L. Cerutti, M. Zahn-Zabal, C. V. Jongeneel, and L. Falquet. 2004. MyHits: a new interactive resource for protein annotation and domain identification. Nucleic Acids Res. 32:W332-W335. (Pubitemid 38997353)
    • (2004) Nucleic Acids Research , vol.32 , Issue.WEB SERVER ISS
    • Pagni, M.1    Ioannidis, V.2    Cerutti, L.3    Zahn-Zabal, M.4    Jongeneel, C.V.5    Falquet, L.6
  • 25
    • 0034734383 scopus 로고    scopus 로고
    • Structure and function in the uracil-DNA glycosylase superfamily
    • Pearl, L. H. 2000. Structure and function in the uracil-DNA glycosylase superfamily. Mutat. Res. 460:165-181.
    • (2000) Mutat. Res. , vol.460 , pp. 165-181
    • Pearl, L.H.1
  • 26
    • 0142075322 scopus 로고    scopus 로고
    • The molecular basis for A-site mutations conferring aminoglycoside resistance: Relationship between ribosomal susceptibility and X-ray crystal structures
    • DOI 10.1002/cbic.200300657
    • Pfister, P., S. Hobbie, Q. Vicens, E. C. Bottger, and E. Westhof. 2003. The molecular basis for A-site mutations conferring aminoglycoside resistance: relationship between ribosomal susceptibility and X-ray crystal structures. Chembiochem 4:1078-1088. (Pubitemid 37267597)
    • (2003) ChemBioChem , vol.4 , Issue.10 , pp. 1078-1088
    • Pfister, P.1    Hobbie, S.2    Vicens, Q.3    Bottger, E.C.4    Westhof, E.5
  • 27
    • 0028979580 scopus 로고
    • +: A dominant selectable marker for gene replacement in mycobacteria
    • +: a dominant selectable marker for gene replacement in mycobacteria. Mol. Microbiol. 16:991-1000.
    • (1995) Mol. Microbiol. , vol.16 , pp. 991-1000
    • Sander, P.1    Meier, A.2    Bottger, E.C.3
  • 28
    • 0033587149 scopus 로고    scopus 로고
    • Thermostable uracil-DNA glycosylase from Thermotoga maritima, a member of a novel class of DNA repair enzymes
    • Sandigursky, M., and W. A. Franklin. 1999. Thermostable uracil-DNA glycosylase from Thermotoga maritima, a member of a novel class of DNA repair enzymes. Curr. Biol. 9:531-534.
    • (1999) Curr. Biol. , vol.9 , pp. 531-534
    • Sandigursky, M.1    Franklin, W.A.2
  • 29
    • 0034705405 scopus 로고    scopus 로고
    • Uracil-DNA glycosylase in the extreme thermophile Archaeoglobus fulgidus
    • Sandigursky, M., and W. A. Franklin. 2000. Uracil-DNA glycosylase in the extreme thermophile Archaeoglobus fulgidus. J. Biol. Chem. 275:19146-19149.
    • (2000) J. Biol. Chem. , vol.275 , pp. 19146-19149
    • Sandigursky, M.1    Franklin, W.A.2
  • 30
    • 0037124349 scopus 로고    scopus 로고
    • A novel uracil-DNA glycosylase with broad substrate specificity and an unusual active site
    • Sartori, A. A., S. Fitz-Gibbon, H. Yang, J. H. Miller, and J. Jiricny. 2002. A novel uracil-DNA glycosylase with broad substrate specificity and an unusual active site. EMBO J. 21:3182-3191.
    • (2002) EMBO J. , vol.21 , pp. 3182-3191
    • Sartori, A.A.1    Fitz-Gibbon, S.2    Yang, H.3    Miller, J.H.4    Jiricny, J.5
  • 31
    • 0014223593 scopus 로고
    • The reaction of ribonucleosides with nitrous acid. Side products and kinetics
    • Shapiro, R., and S. H. Pohl. 1968. The reaction of ribonucleosides with nitrous acid. Side products and kinetics. Biochemistry 7:448-455.
    • (1968) Biochemistry , vol.7 , pp. 448-455
    • Shapiro, R.1    Pohl, S.H.2
  • 32
    • 0028933306 scopus 로고
    • Properties of a recombinant human uracil-DNA glycosylase from the UNG gene and evidence that UNG encodes the major uracil-DNA glycosylase
    • Slupphaug, G., I. Eftedal, B. Kavli, S. Bharati, N. M. Helle, T. Haug, D. W. Levine, and H. E. Krokan. 1995. Properties of a recombinant human uracil-DNA glycosylase from the UNG gene and evidence that UNG encodes the major uracil-DNA glycosylase. Biochemistry 34:128-138.
    • (1995) Biochemistry , vol.34 , pp. 128-138
    • Slupphaug, G.1    Eftedal, I.2    Kavli, B.3    Bharati, S.4    Helle, N.M.5    Haug, T.6    Levine, D.W.7    Krokan, H.E.8
  • 33
    • 0010935866 scopus 로고
    • Spontaneous mutagenesis: Experimental, genetic and other factors
    • Smith, K. C. 1992. Spontaneous mutagenesis: experimental, genetic and other factors. Mutat. Res. 277:139-162.
    • (1992) Mutat. Res. , vol.277 , pp. 139-162
    • Smith, K.C.1
  • 34
    • 0025081151 scopus 로고
    • Isolation and characterization of efficient plasmid transformation mutants of Mycobacterium smegmatis
    • Snapper, S. B., R. E. Melton, S. Mustafa, T. Kieser, and W. R. Jacobs, Jr. 1990. Isolation and characterization of efficient plasmid transformation mutants of Mycobacterium smegmatis. Mol. Microbiol. 4:1911-1919.
    • (1990) Mol. Microbiol. , vol.4 , pp. 1911-1919
    • Snapper, S.B.1    Melton, R.E.2    Mustafa, S.3    Kieser, T.4    Jacobs Jr., W.R.5
  • 36
    • 34548534747 scopus 로고    scopus 로고
    • Substrate specificities and functional characterization of a thermo-tolerant uracil DNA glycosylase (UdgB) from Mycobacterium tuberculosis
    • DOI 10.1016/j.dnarep.2007.05.001, PII S156878640700184X
    • Srinath, T., S. K. Bharti, and U. Varshney. 2007. Substrate specificities and functional characterization of a thermo-tolerant uracil DNA glycosylase (UdgB) from Mycobacterium tuberculosis. DNA Repair 6:1517-1528. (Pubitemid 47385403)
    • (2007) DNA Repair , vol.6 , Issue.10 , pp. 1517-1528
    • Srinath, T.1    Bharti, S.K.2    Varshney, U.3
  • 37
    • 0037052965 scopus 로고    scopus 로고
    • A novel type of uracil-DNA glycosylase mediating repair of hydrolytic DNA damage in the extremely thermophilic eubacterium Thermus thermophilus
    • Starkuviene, V., and H. J. Fritz. 2002. A novel type of uracil-DNA glycosylase mediating repair of hydrolytic DNA damage in the extremely thermophilic eubacterium Thermus thermophilus. Nucleic Acids Res. 30:2097-2102. (Pubitemid 34567930)
    • (2002) Nucleic Acids Research , vol.30 , Issue.10 , pp. 2097-2102
    • Starkuviene, V.1    Fritz, H.-J.2
  • 38
    • 0019921462 scopus 로고
    • Role of exonuclease III in the base excision repair of uracil-containing DNA
    • Taylor, A. F., and B. Weiss. 1982. Role of exonuclease III in the base excision repair of uracil-containing DNA. J. Bacteriol. 151:351-357.
    • (1982) J. Bacteriol. , vol.151 , pp. 351-357
    • Taylor, A.F.1    Weiss, B.2
  • 39
    • 33746493349 scopus 로고    scopus 로고
    • Tuberculosis chemotherapy: The influence of bacillary stress and damage response pathways on drug efficacy
    • Warner, D. F., and V. Mizrahi. 2006. Tuberculosis chemotherapy: the influence of bacillary stress and damage response pathways on drug efficacy. Clin. Microbiol. Rev. 19:558-570.
    • (2006) Clin. Microbiol. Rev. , vol.19 , pp. 558-570
    • Warner, D.F.1    Mizrahi, V.2
  • 40
    • 0019475150 scopus 로고
    • Synthesis and metabolism of uracil-containing deoxyribonucleic acid in Escherichia coli
    • Warner, H. R., B. K. Duncan, C. Garrett, and J. Neuhard. 1981. Synthesis and metabolism of uracil-containing deoxyribonucleic acid in Escherichia coli. J. Bacteriol. 145:687-695. (Pubitemid 11140392)
    • (1981) Journal of Bacteriology , vol.145 , Issue.2 , pp. 687-695
    • Warner, H.R.1    Duncan, B.K.2    Garrett, C.3    Newhard, J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.