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Volumn 15, Issue 7, 2014, Pages 727-748

Biological Significance of the Importin-β Family-Dependent Nucleocytoplasmic Transport Pathways

Author keywords

Exportin; Importin; Karyopherin; Nuclear pore; Nuclear transport; Nucleocytoplasmic transport receptor; Ran; Transport pathway; Transportin

Indexed keywords

EXPORTIN 4; EXPORTIN 5; EXPORTIN 6; EXPORTIN 7; IMPORTIN 11; IMPORTIN 13; IMPORTIN 9; KARYOPHERIN; KARYOPHERIN BETA; MICRORNA; NUCLEOPORIN; PROTEIN RANBP17; PROTEIN RANBP5; PROTEIN RANBP6; TRANSPORTIN 1; TRANSPORTIN 2; UNCLASSIFIED DRUG;

EID: 84902650683     PISSN: 13989219     EISSN: 16000854     Source Type: Journal    
DOI: 10.1111/tra.12174     Document Type: Review
Times cited : (113)

References (204)
  • 1
    • 0042830859 scopus 로고    scopus 로고
    • Nucleocytoplasmic transport: taking an inventory
    • Fried H, Kutay U. Nucleocytoplasmic transport: taking an inventory. Cell Mol Life Sci 2003;60:1659-1688.
    • (2003) Cell Mol Life Sci , vol.60 , pp. 1659-1688
    • Fried, H.1    Kutay, U.2
  • 3
    • 0030570091 scopus 로고    scopus 로고
    • Role of the nuclear transport factor p10 in nuclear import
    • Nehrbass U, Blobel G. Role of the nuclear transport factor p10 in nuclear import. Science 1996;272:120-122.
    • (1996) Science , vol.272 , pp. 120-122
    • Nehrbass, U.1    Blobel, G.2
  • 4
    • 84902666472 scopus 로고
    • mRNA export and the TREX complex
    • Katahira J. mRNA export and the TREX complex. Biochim Biophys Acta 1819;2012:507-513.
    • (1819) Biochim Biophys Acta , vol.2012 , pp. 507-513
    • Katahira, J.1
  • 5
    • 84860323242 scopus 로고    scopus 로고
    • Hikeshi, a nuclear import carrier for Hsp70s, protects cells from heat shock-induced nuclear damage
    • Kose S, Furuta M, Imamoto N. Hikeshi, a nuclear import carrier for Hsp70s, protects cells from heat shock-induced nuclear damage. Cell 2012;149:578-589.
    • (2012) Cell , vol.149 , pp. 578-589
    • Kose, S.1    Furuta, M.2    Imamoto, N.3
  • 6
    • 47849096203 scopus 로고    scopus 로고
    • Evolutionary and transcriptional analysis of karyopherin beta superfamily proteins
    • Quan Y, Ji ZL, Wang X, Tartakoff AM, Tao T. Evolutionary and transcriptional analysis of karyopherin beta superfamily proteins. Mol Cell Proteomics 2008;7:1254-1269.
    • (2008) Mol Cell Proteomics , vol.7 , pp. 1254-1269
    • Quan, Y.1    Ji, Z.L.2    Wang, X.3    Tartakoff, A.M.4    Tao, T.5
  • 8
    • 33746776838 scopus 로고    scopus 로고
    • Rules for nuclear localization sequence recognition by karyopherin beta 2
    • Lee BJ, Cansizoglu AE, Suel KE, Louis TH, Zhang Z, Chook YM. Rules for nuclear localization sequence recognition by karyopherin beta 2. Cell 2006;126:543-558.
    • (2006) Cell , vol.126 , pp. 543-558
    • Lee, B.J.1    Cansizoglu, A.E.2    Suel, K.E.3    Louis, T.H.4    Zhang, Z.5    Chook, Y.M.6
  • 9
    • 33947726050 scopus 로고    scopus 로고
    • CRM1-mediated nuclear export: to the pore and beyond
    • Hutten S, Kehlenbach RH. CRM1-mediated nuclear export: to the pore and beyond. Trends Cell Biol 2007;17:193-201.
    • (2007) Trends Cell Biol , vol.17 , pp. 193-201
    • Hutten, S.1    Kehlenbach, R.H.2
  • 10
    • 34247135913 scopus 로고    scopus 로고
    • Classical nuclear localization signals: definition, function, and interaction with importin alpha
    • Lange A, Mills RE, Lange CJ, Stewart M, Devine SE, Corbett AH. Classical nuclear localization signals: definition, function, and interaction with importin alpha. J Biol Chem 2007;282:5101-5105.
    • (2007) J Biol Chem , vol.282 , pp. 5101-5105
    • Lange, A.1    Mills, R.E.2    Lange, C.J.3    Stewart, M.4    Devine, S.E.5    Corbett, A.H.6
  • 11
    • 33646482468 scopus 로고    scopus 로고
    • Karyopherin flexibility in nucleocytoplasmic transport
    • Conti E, Muller CW, Stewart M. Karyopherin flexibility in nucleocytoplasmic transport. Curr Opin Struct Biol 2006;16:237-244.
    • (2006) Curr Opin Struct Biol , vol.16 , pp. 237-244
    • Conti, E.1    Muller, C.W.2    Stewart, M.3
  • 12
    • 34548627531 scopus 로고    scopus 로고
    • Structural biology of nucleocytoplasmic transport
    • Cook A, Bono F, Jinek M, Conti E. Structural biology of nucleocytoplasmic transport. Annu Rev Biochem 2007;76:647-671.
    • (2007) Annu Rev Biochem , vol.76 , pp. 647-671
    • Cook, A.1    Bono, F.2    Jinek, M.3    Conti, E.4
  • 13
    • 0033922776 scopus 로고    scopus 로고
    • Upstream and downstream of Ran GTPase
    • Nishimoto T. Upstream and downstream of Ran GTPase. Biol Chem 2000;381:397-405.
    • (2000) Biol Chem , vol.381 , pp. 397-405
    • Nishimoto, T.1
  • 14
  • 15
    • 33847176295 scopus 로고    scopus 로고
    • Molecular mechanism of the nuclear protein import cycle
    • Stewart M. Molecular mechanism of the nuclear protein import cycle. Nat Rev Mol Cell Biol 2007;8:195-208.
    • (2007) Nat Rev Mol Cell Biol , vol.8 , pp. 195-208
    • Stewart, M.1
  • 18
    • 84902655320 scopus 로고
    • Nuclear import by karyopherin-betas: recognition and inhibition
    • Chook YM, Suel KE. Nuclear import by karyopherin-betas: recognition and inhibition. Biochim Biophys Acta 1813;2011:1593-1606.
    • (1813) Biochim Biophys Acta , vol.2011 , pp. 1593-1606
    • Chook, Y.M.1    Suel, K.E.2
  • 19
    • 84872486137 scopus 로고    scopus 로고
    • Early growth response protein 1 upregulation and nuclear translocation by 2'-benzoyloxycinnamaldehyde induces prostate cancer cell death
    • Kang HS, Ock J, Lee HJ, Lee YJ, Kwon BM, Hong SH. Early growth response protein 1 upregulation and nuclear translocation by 2'-benzoyloxycinnamaldehyde induces prostate cancer cell death. Cancer Lett 2013;329:217-227.
    • (2013) Cancer Lett , vol.329 , pp. 217-227
    • Kang, H.S.1    Ock, J.2    Lee, H.J.3    Lee, Y.J.4    Kwon, B.M.5    Hong, S.H.6
  • 20
    • 84879100602 scopus 로고    scopus 로고
    • CCCTC-binding factor controls its own nuclear transport via regulating the expression of importin 13
    • Wang R, Shen J, Huang P, Zhu X. CCCTC-binding factor controls its own nuclear transport via regulating the expression of importin 13. Mol Cells 2013;35:388-395.
    • (2013) Mol Cells , vol.35 , pp. 388-395
    • Wang, R.1    Shen, J.2    Huang, P.3    Zhu, X.4
  • 23
    • 79951887419 scopus 로고    scopus 로고
    • Forkhead box o as a sensor, mediator, and regulator of redox signaling
    • de Keizer PL, Burgering BM, Dansen TB. Forkhead box o as a sensor, mediator, and regulator of redox signaling. Antioxid Redox Signal 2011;14:1093-1106.
    • (2011) Antioxid Redox Signal , vol.14 , pp. 1093-1106
    • de Keizer, P.L.1    Burgering, B.M.2    Dansen, T.B.3
  • 24
    • 34347393968 scopus 로고    scopus 로고
    • Involvement of transportin 2-mediated HuR import in muscle cell differentiation
    • van der Giessen K, Gallouzi IE. Involvement of transportin 2-mediated HuR import in muscle cell differentiation. Mol Biol Cell 2007;18:2619-2629.
    • (2007) Mol Biol Cell , vol.18 , pp. 2619-2629
    • van der Giessen, K.1    Gallouzi, I.E.2
  • 26
    • 79960431405 scopus 로고    scopus 로고
    • Transportin 2 regulates apoptosis through the RNA-binding protein HuR
    • von Roretz C, Macri AM, Gallouzi IE. Transportin 2 regulates apoptosis through the RNA-binding protein HuR. J Biol Chem 2011;286:25983-25991.
    • (2011) J Biol Chem , vol.286 , pp. 25983-25991
    • von Roretz, C.1    Macri, A.M.2    Gallouzi, I.E.3
  • 27
    • 79955455006 scopus 로고    scopus 로고
    • Importin alpha protein acts as a negative regulator for Snail protein nuclear import
    • Sekimoto T, Miyamoto Y, Arai S, Yoneda Y. Importin alpha protein acts as a negative regulator for Snail protein nuclear import. J Biol Chem 2011;286:15126-15131.
    • (2011) J Biol Chem , vol.286 , pp. 15126-15131
    • Sekimoto, T.1    Miyamoto, Y.2    Arai, S.3    Yoneda, Y.4
  • 29
    • 56549083885 scopus 로고    scopus 로고
    • Regional distribution of importin subtype mRNA expression in the nervous system: study of early postnatal and adult mouse
    • Hosokawa K, Nishi M, Sakamoto H, Tanaka Y, Kawata M. Regional distribution of importin subtype mRNA expression in the nervous system: study of early postnatal and adult mouse. Neuroscience 2008;157:864-877.
    • (2008) Neuroscience , vol.157 , pp. 864-877
    • Hosokawa, K.1    Nishi, M.2    Sakamoto, H.3    Tanaka, Y.4    Kawata, M.5
  • 30
    • 80355148459 scopus 로고    scopus 로고
    • Distinct effects of importin alpha2 and alpha4 on Oct3/4 localization and expression in mouse embryonic stem cells
    • Young JC, Major AT, Miyamoto Y, Loveland KL, Jans DA. Distinct effects of importin alpha2 and alpha4 on Oct3/4 localization and expression in mouse embryonic stem cells. FASEB J 2011;25:3958-3965.
    • (2011) FASEB J , vol.25 , pp. 3958-3965
    • Young, J.C.1    Major, A.T.2    Miyamoto, Y.3    Loveland, K.L.4    Jans, D.A.5
  • 31
    • 30344449508 scopus 로고    scopus 로고
    • Expression of nuclear transport importins beta 1 and beta 3 is regulated during rodent spermatogenesis
    • Loveland KL, Hogarth C, Szczepny A, Prabhu SM, Jans DA. Expression of nuclear transport importins beta 1 and beta 3 is regulated during rodent spermatogenesis. Biol Reprod 2006;74:67-74.
    • (2006) Biol Reprod , vol.74 , pp. 67-74
    • Loveland, K.L.1    Hogarth, C.2    Szczepny, A.3    Prabhu, S.M.4    Jans, D.A.5
  • 32
    • 0043245880 scopus 로고    scopus 로고
    • Expression of testicular germ cell genes identified by differential display analysis
    • Anway MD, Li Y, Ravindranath N, Dym M, Griswold MD. Expression of testicular germ cell genes identified by differential display analysis. J Androl 2003;24:173-184.
    • (2003) J Androl , vol.24 , pp. 173-184
    • Anway, M.D.1    Li, Y.2    Ravindranath, N.3    Dym, M.4    Griswold, M.D.5
  • 33
    • 27744531947 scopus 로고    scopus 로고
    • Cloning and characterization of rat importin 9: implication for its neuronal function
    • Kortvely E, Burkovics P, Varszegi S, Gulya K. Cloning and characterization of rat importin 9: implication for its neuronal function. Brain Res Mol Brain Res 2005;139:103-114.
    • (2005) Brain Res Mol Brain Res , vol.139 , pp. 103-114
    • Kortvely, E.1    Burkovics, P.2    Varszegi, S.3    Gulya, K.4
  • 36
    • 84878013022 scopus 로고    scopus 로고
    • Expression and subcellular distribution of imp13 are regulated in brain development
    • You P, Peng Z, Wang Y, Tao T. Expression and subcellular distribution of imp13 are regulated in brain development. In Vitro Cell Dev Biol Anim 2013;49:346-353.
    • (2013) In Vitro Cell Dev Biol Anim , vol.49 , pp. 346-353
    • You, P.1    Peng, Z.2    Wang, Y.3    Tao, T.4
  • 38
    • 79651474455 scopus 로고    scopus 로고
    • RANBP17 is localized to the XY body of spermatocytes and interacts with SPEM1 on the manchette of elongating spermatids
    • Bao J, Wu Q, Song R, Jie Z, Zheng H, Xu C, Yan W. RANBP17 is localized to the XY body of spermatocytes and interacts with SPEM1 on the manchette of elongating spermatids. Mol Cell Endocrinol 2011;333:134-142.
    • (2011) Mol Cell Endocrinol , vol.333 , pp. 134-142
    • Bao, J.1    Wu, Q.2    Song, R.3    Jie, Z.4    Zheng, H.5    Xu, C.6    Yan, W.7
  • 39
    • 79955090229 scopus 로고    scopus 로고
    • Transportin 1 in the mouse brain: appearance in regions of neurogenesis, cerebrospinal fluid production/sensing, and circadian clock
    • Sato M, Mizoro Y, Atobe Y, Fujimoto Y, Yamaguchi Y, Fustin JM, Doi M, Okamura H. Transportin 1 in the mouse brain: appearance in regions of neurogenesis, cerebrospinal fluid production/sensing, and circadian clock. J Comp Neurol 2011;519:1770-1780.
    • (2011) J Comp Neurol , vol.519 , pp. 1770-1780
    • Sato, M.1    Mizoro, Y.2    Atobe, Y.3    Fujimoto, Y.4    Yamaguchi, Y.5    Fustin, J.M.6    Doi, M.7    Okamura, H.8
  • 41
    • 0028889656 scopus 로고
    • Cloning and characterization of a cellular apoptosis susceptibility gene, the human homologue to the yeast chromosome segregation gene CSE1
    • Brinkmann U, Brinkmann E, Gallo M, Pastan I. Cloning and characterization of a cellular apoptosis susceptibility gene, the human homologue to the yeast chromosome segregation gene CSE1. Proc Natl Acad Sci U S A 1995;92:10427-10431.
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 10427-10431
    • Brinkmann, U.1    Brinkmann, E.2    Gallo, M.3    Pastan, I.4
  • 42
    • 0030701840 scopus 로고    scopus 로고
    • Molecular cloning and cell cycle-dependent expression of mammalian CRM1, a protein involved in nuclear export of proteins
    • Kudo N, Khochbin S, Nishi K, Kitano K, Yanagida M, Yoshida M, Horinouchi S. Molecular cloning and cell cycle-dependent expression of mammalian CRM1, a protein involved in nuclear export of proteins. J Biol Chem 1997;272:29742-29751.
    • (1997) J Biol Chem , vol.272 , pp. 29742-29751
    • Kudo, N.1    Khochbin, S.2    Nishi, K.3    Kitano, K.4    Yanagida, M.5    Yoshida, M.6    Horinouchi, S.7
  • 43
    • 77952094192 scopus 로고    scopus 로고
    • Steroidal regulation of uterine miRNAs is associated with modulation of the miRNA biogenesis components Exportin-5 and Dicer1
    • Nothnick WB, Healy C, Hong X. Steroidal regulation of uterine miRNAs is associated with modulation of the miRNA biogenesis components Exportin-5 and Dicer1. Endocrine 2010;37:265-273.
    • (2010) Endocrine , vol.37 , pp. 265-273
    • Nothnick, W.B.1    Healy, C.2    Hong, X.3
  • 46
    • 46149125526 scopus 로고    scopus 로고
    • Involvement of importin-4 in the transport of transition protein 2 into the spermatid nucleus
    • Pradeepa MM, Manjunatha S, Sathish V, Agrawal S, Rao MR. Involvement of importin-4 in the transport of transition protein 2 into the spermatid nucleus. Mol Cell Biol 2008;28:4331-4341.
    • (2008) Mol Cell Biol , vol.28 , pp. 4331-4341
    • Pradeepa, M.M.1    Manjunatha, S.2    Sathish, V.3    Agrawal, S.4    Rao, M.R.5
  • 47
    • 73249135182 scopus 로고    scopus 로고
    • Genome-wide profiling of developmental, hormonal or environmental responsiveness of the nucleocytoplasmic transport receptors in Arabidopsis
    • Huang JG, Yang M, Liu P, Yang GD, Wu CA, Zheng CC. Genome-wide profiling of developmental, hormonal or environmental responsiveness of the nucleocytoplasmic transport receptors in Arabidopsis. Gene 2010;451:38-44.
    • (2010) Gene , vol.451 , pp. 38-44
    • Huang, J.G.1    Yang, M.2    Liu, P.3    Yang, G.D.4    Wu, C.A.5    Zheng, C.C.6
  • 48
    • 58949099399 scopus 로고    scopus 로고
    • Biomphalaria glabrata transcriptome: cDNA microarray profiling identifies resistant- and susceptible-specific gene expression in haemocytes from snail strains exposed to Schistosoma mansoni
    • Lockyer AE, Spinks J, Kane RA, Hoffmann KF, Fitzpatrick JM, Rollinson D, Noble LR, Jones CS. Biomphalaria glabrata transcriptome: cDNA microarray profiling identifies resistant- and susceptible-specific gene expression in haemocytes from snail strains exposed to Schistosoma mansoni. BMC Genomics 2008;9:634.
    • (2008) BMC Genomics , vol.9 , pp. 634
    • Lockyer, A.E.1    Spinks, J.2    Kane, R.A.3    Hoffmann, K.F.4    Fitzpatrick, J.M.5    Rollinson, D.6    Noble, L.R.7    Jones, C.S.8
  • 49
    • 36448942129 scopus 로고    scopus 로고
    • Genes involved in the RNA interference pathway are differentially expressed during sea urchin development
    • Song JL, Wessel GM. Genes involved in the RNA interference pathway are differentially expressed during sea urchin development. Dev Dyn 2007;236:3180-3190.
    • (2007) Dev Dyn , vol.236 , pp. 3180-3190
    • Song, J.L.1    Wessel, G.M.2
  • 50
    • 72949116994 scopus 로고    scopus 로고
    • Senescence-related functional nuclear barrier by down-regulation of nucleo-cytoplasmic trafficking gene expression
    • Kim SY, Ryu SJ, Ahn HJ, Choi HR, Kang HT, Park SC. Senescence-related functional nuclear barrier by down-regulation of nucleo-cytoplasmic trafficking gene expression. Biochem Biophys Res Commun 2010;391:28-32.
    • (2010) Biochem Biophys Res Commun , vol.391 , pp. 28-32
    • Kim, S.Y.1    Ryu, S.J.2    Ahn, H.J.3    Choi, H.R.4    Kang, H.T.5    Park, S.C.6
  • 51
    • 67349223897 scopus 로고    scopus 로고
    • Time course of housekeeping gene expression changes in diffuse alveolar damage induced by hyperoxia exposure in mice
    • Shimada I, Matsui K, Iida R, Tsubota E, Matsuki T. Time course of housekeeping gene expression changes in diffuse alveolar damage induced by hyperoxia exposure in mice. Leg Med (Tokyo) 2009;11(Suppl. 1):S151-S154.
    • (2009) Leg Med (Tokyo) , vol.11 , Issue.SUPPL. 1
    • Shimada, I.1    Matsui, K.2    Iida, R.3    Tsubota, E.4    Matsuki, T.5
  • 52
    • 0036290393 scopus 로고    scopus 로고
    • Age-associated reduction of nuclear protein import in human fibroblasts
    • Pujol G, Soderqvist H, Radu A. Age-associated reduction of nuclear protein import in human fibroblasts. Biochem Biophys Res Commun 2002;294:354-358.
    • (2002) Biochem Biophys Res Commun , vol.294 , pp. 354-358
    • Pujol, G.1    Soderqvist, H.2    Radu, A.3
  • 53
    • 33646805774 scopus 로고    scopus 로고
    • 1,25-Dihydroxyvitamin D3 suppresses exportin expression in human promyelocytic leukemia HL-60 cells
    • Suzuki T, Koyama Y, Hayakawa S, Munakata H, Isemura M. 1, 25-Dihydroxyvitamin D3 suppresses exportin expression in human promyelocytic leukemia HL-60 cells. Biomed Res 2006;27:89-92.
    • (2006) Biomed Res , vol.27 , pp. 89-92
    • Suzuki, T.1    Koyama, Y.2    Hayakawa, S.3    Munakata, H.4    Isemura, M.5
  • 54
    • 33746359700 scopus 로고    scopus 로고
    • DNA microarray analysis of changes in gene expression induced by 1,25-dihydroxyvitamin D3 in human promyelocytic leukemia HL-60 cells
    • Suzuki T, Tazoe H, Taguchi K, Koyama Y, Ichikawa H, Hayakawa S, Munakata H, Isemura M. DNA microarray analysis of changes in gene expression induced by 1, 25-dihydroxyvitamin D3 in human promyelocytic leukemia HL-60 cells. Biomed Res 2006;27:99-109.
    • (2006) Biomed Res , vol.27 , pp. 99-109
    • Suzuki, T.1    Tazoe, H.2    Taguchi, K.3    Koyama, Y.4    Ichikawa, H.5    Hayakawa, S.6    Munakata, H.7    Isemura, M.8
  • 55
    • 48249114419 scopus 로고    scopus 로고
    • Differentiation-associated alteration in gene expression of importins and exportins in human leukemia HL-60 cells
    • Suzuki T, Ishigami Y, Okada N, Kaneko A, Fukutomi R, Isemura M. Differentiation-associated alteration in gene expression of importins and exportins in human leukemia HL-60 cells. Biomed Res 2008;29:141-145.
    • (2008) Biomed Res , vol.29 , pp. 141-145
    • Suzuki, T.1    Ishigami, Y.2    Okada, N.3    Kaneko, A.4    Fukutomi, R.5    Isemura, M.6
  • 56
    • 84902666473 scopus 로고
    • Expression of nucleocytoplasmic transport machinery: clues to regulation of spermatogenic development
    • Major AT, Whiley PA, Loveland KL. Expression of nucleocytoplasmic transport machinery: clues to regulation of spermatogenic development. Biochim Biophys Acta 1813;2011:1668-1688.
    • (1813) Biochim Biophys Acta , vol.2011 , pp. 1668-1688
    • Major, A.T.1    Whiley, P.A.2    Loveland, K.L.3
  • 58
    • 77949400181 scopus 로고    scopus 로고
    • Comprehensive identification and modified-site mapping of S-nitrosylated targets in prostate epithelial cells
    • Lam YW, Yuan Y, Isaac J, Babu CV, Meller J, Ho SM. Comprehensive identification and modified-site mapping of S-nitrosylated targets in prostate epithelial cells. PLoS One 2010;5:e9075.
    • (2010) PLoS One , vol.5
    • Lam, Y.W.1    Yuan, Y.2    Isaac, J.3    Babu, C.V.4    Meller, J.5    Ho, S.M.6
  • 61
    • 0032578625 scopus 로고    scopus 로고
    • The hCSE1/CAS protein is phosphorylated by HeLa extracts and MEK-1: MEK-1 phosphorylation may modulate the intracellular localization of CAS
    • Scherf U, Kalab P, Dasso M, Pastan I, Brinkmann U. The hCSE1/CAS protein is phosphorylated by HeLa extracts and MEK-1: MEK-1 phosphorylation may modulate the intracellular localization of CAS. Biochem Biophys Res Commun 1998;250:623-628.
    • (1998) Biochem Biophys Res Commun , vol.250 , pp. 623-628
    • Scherf, U.1    Kalab, P.2    Dasso, M.3    Pastan, I.4    Brinkmann, U.5
  • 62
    • 42549125623 scopus 로고    scopus 로고
    • Protein phosphatase 1H, overexpressed in colon adenocarcinoma, is associated with CSE1L
    • Sugiura T, Noguchi Y, Sakurai K, Hattori C. Protein phosphatase 1H, overexpressed in colon adenocarcinoma, is associated with CSE1L. Cancer Biol Ther 2008;7:285-292.
    • (2008) Cancer Biol Ther , vol.7 , pp. 285-292
    • Sugiura, T.1    Noguchi, Y.2    Sakurai, K.3    Hattori, C.4
  • 63
    • 84862233980 scopus 로고    scopus 로고
    • PARP16/ARTD15 is a novel endoplasmic-reticulum-associated mono-ADP-ribosyltransferase that interacts with, and modifies karyopherin-ß1
    • Di Paola S, Micaroni M, Di Tullio G, Buccione R, Di Girolamo M. PARP16/ARTD15 is a novel endoplasmic-reticulum-associated mono-ADP-ribosyltransferase that interacts with, and modifies karyopherin-ß1. PLoS One 2012;7:e37352.
    • (2012) PLoS One , vol.7
    • Di Paola, S.1    Micaroni, M.2    Di Tullio, G.3    Buccione, R.4    Di Girolamo, M.5
  • 64
    • 79952454775 scopus 로고    scopus 로고
    • Reduction of exportin 6 activity leads to actin accumulation via failure of RanGTP restoration and NTF2 sequestration in the nuclei of senescent cells
    • Park SH, Park TJ, Lim IK. Reduction of exportin 6 activity leads to actin accumulation via failure of RanGTP restoration and NTF2 sequestration in the nuclei of senescent cells. Exp Cell Res 2011;317:941-954.
    • (2011) Exp Cell Res , vol.317 , pp. 941-954
    • Park, S.H.1    Park, T.J.2    Lim, I.K.3
  • 66
    • 78649894789 scopus 로고    scopus 로고
    • A novel role of CPEB3 in regulating EGFR gene transcription via association with Stat5b in neurons
    • Peng SC, Lai YT, Huang HY, Huang HD, Huang YS. A novel role of CPEB3 in regulating EGFR gene transcription via association with Stat5b in neurons. Nucleic Acids Res 2010;38:7446-7457.
    • (2010) Nucleic Acids Res , vol.38 , pp. 7446-7457
    • Peng, S.C.1    Lai, Y.T.2    Huang, H.Y.3    Huang, H.D.4    Huang, Y.S.5
  • 67
    • 0032576573 scopus 로고    scopus 로고
    • Specific binding of the karyopherin Kap121p to a subunit of the nuclear pore complex containing Nup53p, Nup59p, and Nup170p
    • Marelli M, Aitchison JD, Wozniak RW. Specific binding of the karyopherin Kap121p to a subunit of the nuclear pore complex containing Nup53p, Nup59p, and Nup170p. J Cell Biol 1998;143:1813-1830.
    • (1998) J Cell Biol , vol.143 , pp. 1813-1830
    • Marelli, M.1    Aitchison, J.D.2    Wozniak, R.W.3
  • 68
    • 0347611086 scopus 로고    scopus 로고
    • Cell cycle regulated transport controlled by alterations in the nuclear pore complex
    • Makhnevych T, Lusk CP, Anderson AM, Aitchison JD, Wozniak RW. Cell cycle regulated transport controlled by alterations in the nuclear pore complex. Cell 2003;115:813-823.
    • (2003) Cell , vol.115 , pp. 813-823
    • Makhnevych, T.1    Lusk, C.P.2    Anderson, A.M.3    Aitchison, J.D.4    Wozniak, R.W.5
  • 69
    • 84877694405 scopus 로고    scopus 로고
    • Structural basis for cell-cycle dependent nuclear import mediated by the karyopherin Kap121p
    • Kobayashi J, Matsuura Y. Structural basis for cell-cycle dependent nuclear import mediated by the karyopherin Kap121p. J Mol Biol 2013;425:1852-1868.
    • (2013) J Mol Biol , vol.425 , pp. 1852-1868
    • Kobayashi, J.1    Matsuura, Y.2
  • 70
    • 73849122773 scopus 로고    scopus 로고
    • Oxidative stress inhibits nuclear protein export by multiple mechanisms that target FG nucleoporins and Crm1
    • Crampton N, Kodiha M, Shrivastava S, Umar R, Stochaj U. Oxidative stress inhibits nuclear protein export by multiple mechanisms that target FG nucleoporins and Crm1. Mol Biol Cell 2009;20:5106-5116.
    • (2009) Mol Biol Cell , vol.20 , pp. 5106-5116
    • Crampton, N.1    Kodiha, M.2    Shrivastava, S.3    Umar, R.4    Stochaj, U.5
  • 71
    • 77953947965 scopus 로고    scopus 로고
    • Yeast karyopherin Kap95 is required for cell cycle progression at Start
    • Taberner FJ, Igual JC. Yeast karyopherin Kap95 is required for cell cycle progression at Start. BMC Cell Biol 2010;11:47.
    • (2010) BMC Cell Biol , vol.11 , pp. 47
    • Taberner, F.J.1    Igual, J.C.2
  • 72
    • 0033615965 scopus 로고    scopus 로고
    • Cell cycle-regulated attachment of the ubiquitin-related protein SUMO to the yeast septins
    • Johnson ES, Blobel G. Cell cycle-regulated attachment of the ubiquitin-related protein SUMO to the yeast septins. J Cell Biol 1999;147:981-994.
    • (1999) J Cell Biol , vol.147 , pp. 981-994
    • Johnson, E.S.1    Blobel, G.2
  • 76
    • 72449173927 scopus 로고    scopus 로고
    • Conservation of the sterol regulatory element-binding protein pathway and its pathobiological importance in Cryptococcus neoformans
    • Chang YC, Ingavale SS, Bien C, Espenshade P, Kwon-Chung KJ. Conservation of the sterol regulatory element-binding protein pathway and its pathobiological importance in Cryptococcus neoformans. Eukaryot Cell 2009;8:1770-1779.
    • (2009) Eukaryot Cell , vol.8 , pp. 1770-1779
    • Chang, Y.C.1    Ingavale, S.S.2    Bien, C.3    Espenshade, P.4    Kwon-Chung, K.J.5
  • 77
    • 0032815863 scopus 로고    scopus 로고
    • Nuclear import of sterol regulatory element-binding protein-2, a basic helix-loop-helix-leucine zipper (bHLH-Zip)-containing transcription factor, occurs through the direct interaction of importin beta with HLH-Zip
    • Nagoshi E, Imamoto N, Sato R, Yoneda Y. Nuclear import of sterol regulatory element-binding protein-2, a basic helix-loop-helix-leucine zipper (bHLH-Zip)-containing transcription factor, occurs through the direct interaction of importin beta with HLH-Zip. Mol Biol Cell 1999;10:2221-2233.
    • (1999) Mol Biol Cell , vol.10 , pp. 2221-2233
    • Nagoshi, E.1    Imamoto, N.2    Sato, R.3    Yoneda, Y.4
  • 80
    • 33748450068 scopus 로고    scopus 로고
    • Stage-specific Importin13 activity influences meiosis of germ cells in the mouse
    • Yamaguchi YL, Tanaka SS, Yasuda K, Matsui Y, Tam PP. Stage-specific Importin13 activity influences meiosis of germ cells in the mouse. Dev Biol 2006;297:350-360.
    • (2006) Dev Biol , vol.297 , pp. 350-360
    • Yamaguchi, Y.L.1    Tanaka, S.S.2    Yasuda, K.3    Matsui, Y.4    Tam, P.P.5
  • 81
    • 0036210710 scopus 로고    scopus 로고
    • Kap121p-mediated nuclear import is required for mating and cellular differentiation in yeast
    • Leslie DM, Grill B, Rout MP, Wozniak RW, Aitchison JD. Kap121p-mediated nuclear import is required for mating and cellular differentiation in yeast. Mol Cell Biol 2002;22:2544-2555.
    • (2002) Mol Cell Biol , vol.22 , pp. 2544-2555
    • Leslie, D.M.1    Grill, B.2    Rout, M.P.3    Wozniak, R.W.4    Aitchison, J.D.5
  • 82
    • 71449105723 scopus 로고    scopus 로고
    • KapI, a non-essential member of the Pse1p/Imp5 karyopherin family, controls colonial and asexual development in Aspergillus nidulans
    • Etxebeste O, Markina-Inarrairaegui A, Garzia A, Herrero-Garcia E, Ugalde U, Espeso EA. KapI, a non-essential member of the Pse1p/Imp5 karyopherin family, controls colonial and asexual development in Aspergillus nidulans. Microbiology 2009;155:3934-3945.
    • (2009) Microbiology , vol.155 , pp. 3934-3945
    • Etxebeste, O.1    Markina-Inarrairaegui, A.2    Garzia, A.3    Herrero-Garcia, E.4    Ugalde, U.5    Espeso, E.A.6
  • 83
    • 84862825917 scopus 로고    scopus 로고
    • The karyopherin Sal3 is required for nuclear import of the core RNA interference pathway protein Rdp1
    • Park J, Freitag SI, Young PG, Hobman TC. The karyopherin Sal3 is required for nuclear import of the core RNA interference pathway protein Rdp1. Traffic 2012;13:520-531.
    • (2012) Traffic , vol.13 , pp. 520-531
    • Park, J.1    Freitag, S.I.2    Young, P.G.3    Hobman, T.C.4
  • 84
    • 0020606355 scopus 로고
    • Leptomycins A and B, new antifungal antibiotics. I. Taxonomy of the producing strain and their fermentation, purification and characterization
    • Hamamoto T, Gunji S, Tsuji H, Beppu T. Leptomycins A and B, new antifungal antibiotics. I. Taxonomy of the producing strain and their fermentation, purification and characterization. J Antibiot (Tokyo) 1983;36:639-645.
    • (1983) J Antibiot (Tokyo) , vol.36 , pp. 639-645
    • Hamamoto, T.1    Gunji, S.2    Tsuji, H.3    Beppu, T.4
  • 85
    • 0020571348 scopus 로고
    • Leptomycins A and B, new antifungal antibiotics. II. Structure elucidation
    • Hamamoto T, Seto H, Beppu T. Leptomycins A and B, new antifungal antibiotics. II. Structure elucidation. J Antibiot (Tokyo) 1983;36:646-650.
    • (1983) J Antibiot (Tokyo) , vol.36 , pp. 646-650
    • Hamamoto, T.1    Seto, H.2    Beppu, T.3
  • 87
    • 23144449790 scopus 로고    scopus 로고
    • Temporal and spatial control of nucleophosmin by the Ran-Crm1 complex in centrosome duplication
    • Wang W, Budhu A, Forgues M, Wang XW. Temporal and spatial control of nucleophosmin by the Ran-Crm1 complex in centrosome duplication. Nat Cell Biol 2005;7:823-830.
    • (2005) Nat Cell Biol , vol.7 , pp. 823-830
    • Wang, W.1    Budhu, A.2    Forgues, M.3    Wang, X.W.4
  • 88
    • 0035911152 scopus 로고    scopus 로고
    • The karyopherin Kap142p/Msn5p mediates nuclear import and nuclear export of different cargo proteins
    • Yoshida K, Blobel G. The karyopherin Kap142p/Msn5p mediates nuclear import and nuclear export of different cargo proteins. J Cell Biol 2001;152:729-740.
    • (2001) J Cell Biol , vol.152 , pp. 729-740
    • Yoshida, K.1    Blobel, G.2
  • 89
    • 21744453148 scopus 로고    scopus 로고
    • tRNA actively shuttles between the nucleus and cytosol in yeast
    • Takano A, Endo T, Yoshihisa T. tRNA actively shuttles between the nucleus and cytosol in yeast. Science 2005;309:140-142.
    • (2005) Science , vol.309 , pp. 140-142
    • Takano, A.1    Endo, T.2    Yoshihisa, T.3
  • 90
    • 84886937862 scopus 로고    scopus 로고
    • Genome-wide investigation of the role of the tRNA nuclear-cytoplasmic trafficking pathway in regulation of the yeast Saccharomyces cerevisiae transcriptome and proteome
    • Chu HY, Hopper AK. Genome-wide investigation of the role of the tRNA nuclear-cytoplasmic trafficking pathway in regulation of the yeast Saccharomyces cerevisiae transcriptome and proteome. Mol Cell Biol 2013;33:4241-4254.
    • (2013) Mol Cell Biol , vol.33 , pp. 4241-4254
    • Chu, H.Y.1    Hopper, A.K.2
  • 91
    • 0032481048 scopus 로고    scopus 로고
    • The receptor Msn5 exports the phosphorylated transcription factor Pho4 out of the nucleus
    • Kaffman A, Rank NM, O'Neill EM, Huang LS, O'Shea EK. The receptor Msn5 exports the phosphorylated transcription factor Pho4 out of the nucleus. Nature 1998;396:482-486.
    • (1998) Nature , vol.396 , pp. 482-486
    • Kaffman, A.1    Rank, N.M.2    O'Neill, E.M.3    Huang, L.S.4    O'Shea, E.K.5
  • 92
    • 0033200354 scopus 로고    scopus 로고
    • Nuclear export of Far1p in response to pheromones requires the export receptor Msn5p/Ste21p
    • Blondel M, Alepuz PM, Huang LS, Shaham S, Ammerer G, Peter M. Nuclear export of Far1p in response to pheromones requires the export receptor Msn5p/Ste21p. Genes Dev 1999;13:2284-2300.
    • (1999) Genes Dev , vol.13 , pp. 2284-2300
    • Blondel, M.1    Alepuz, P.M.2    Huang, L.S.3    Shaham, S.4    Ammerer, G.5    Peter, M.6
  • 93
    • 0033523996 scopus 로고    scopus 로고
    • The nuclear exportin Msn5 is required for nuclear export of the Mig1 glucose repressor of Saccharomyces cerevisiae
    • DeVit MJ, Johnston M. The nuclear exportin Msn5 is required for nuclear export of the Mig1 glucose repressor of Saccharomyces cerevisiae. Curr Biol 1999;9:1231-1241.
    • (1999) Curr Biol , vol.9 , pp. 1231-1241
    • DeVit, M.J.1    Johnston, M.2
  • 94
    • 0031762569 scopus 로고    scopus 로고
    • Regulators of pseudohyphal differentiation in Saccharomyces cerevisiae identified through multicopy suppressor analysis in ammonium permease mutant strains
    • Lorenz MC, Heitman J. Regulators of pseudohyphal differentiation in Saccharomyces cerevisiae identified through multicopy suppressor analysis in ammonium permease mutant strains. Genetics 1998;150:1443-1457.
    • (1998) Genetics , vol.150 , pp. 1443-1457
    • Lorenz, M.C.1    Heitman, J.2
  • 95
    • 84857855634 scopus 로고    scopus 로고
    • Msn5p is involved in formaldehyde resistance but not in oxidative stress response in the methylotrophic yeast Candida boidinii
    • Zhai Z, Yurimoto H, Sakai Y. Msn5p is involved in formaldehyde resistance but not in oxidative stress response in the methylotrophic yeast Candida boidinii. Biosci Biotechnol Biochem 2012;76:299-304.
    • (2012) Biosci Biotechnol Biochem , vol.76 , pp. 299-304
    • Zhai, Z.1    Yurimoto, H.2    Sakai, Y.3
  • 97
    • 0032510462 scopus 로고    scopus 로고
    • Identification of a nuclear export receptor for tRNA
    • Arts GJ, Fornerod M, Mattaj IW. Identification of a nuclear export receptor for tRNA. Curr Biol 1998;8:305-314.
    • (1998) Curr Biol , vol.8 , pp. 305-314
    • Arts, G.J.1    Fornerod, M.2    Mattaj, I.W.3
  • 98
    • 0031771756 scopus 로고    scopus 로고
    • Yeast Los1p has properties of an exportin-like nucleocytoplasmic transport factor for tRNA
    • Hellmuth K, Lau DM, Bischoff FR, Kunzler M, Hurt E, Simos G. Yeast Los1p has properties of an exportin-like nucleocytoplasmic transport factor for tRNA. Mol Cell Biol 1998;18:6374-6386.
    • (1998) Mol Cell Biol , vol.18 , pp. 6374-6386
    • Hellmuth, K.1    Lau, D.M.2    Bischoff, F.R.3    Kunzler, M.4    Hurt, E.5    Simos, G.6
  • 99
    • 0018841174 scopus 로고
    • Processing of intervening sequences: a new yeast mutant which fails to excise intervening sequences from precursor tRNAs
    • Hopper AK, Schultz LD, Shapiro RA. Processing of intervening sequences: a new yeast mutant which fails to excise intervening sequences from precursor tRNAs. Cell 1980;19:741-751.
    • (1980) Cell , vol.19 , pp. 741-751
    • Hopper, A.K.1    Schultz, L.D.2    Shapiro, R.A.3
  • 101
    • 84856464862 scopus 로고    scopus 로고
    • Altered nuclear tRNA metabolism in La-deleted Schizosaccharomyces pombe is accompanied by a nutritional stress response involving Atf1p and Pcr1p that is suppressible by Xpo-t/Los1p
    • Cherkasova V, Maury LL, Bacikova D, Pridham K, Bahler J, Maraia RJ. Altered nuclear tRNA metabolism in La-deleted Schizosaccharomyces pombe is accompanied by a nutritional stress response involving Atf1p and Pcr1p that is suppressible by Xpo-t/Los1p. Mol Biol Cell 2012;23:480-491.
    • (2012) Mol Biol Cell , vol.23 , pp. 480-491
    • Cherkasova, V.1    Maury, L.L.2    Bacikova, D.3    Pridham, K.4    Bahler, J.5    Maraia, R.J.6
  • 102
    • 0342276108 scopus 로고    scopus 로고
    • Export of importin alpha from the nucleus is mediated by a specific nuclear transport factor
    • Kutay U, Bischoff FR, Kostka S, Kraft R, Gorlich D. Export of importin alpha from the nucleus is mediated by a specific nuclear transport factor. Cell 1997;90:1061-1071.
    • (1997) Cell , vol.90 , pp. 1061-1071
    • Kutay, U.1    Bischoff, F.R.2    Kostka, S.3    Kraft, R.4    Gorlich, D.5
  • 103
    • 0032567443 scopus 로고    scopus 로고
    • Cse1p is required for export of Srp1p/importin-alpha from the nucleus in Saccharomyces cerevisiae
    • Hood JK, Silver PA. Cse1p is required for export of Srp1p/importin-alpha from the nucleus in Saccharomyces cerevisiae. J Biol Chem 1998;273:35142-35146.
    • (1998) J Biol Chem , vol.273 , pp. 35142-35146
    • Hood, J.K.1    Silver, P.A.2
  • 104
    • 0032555365 scopus 로고    scopus 로고
    • Cse1p functions as the nuclear export receptor for importin alpha in yeast
    • Kunzler M, Hurt EC. Cse1p functions as the nuclear export receptor for importin alpha in yeast. FEBS Lett 1998;433:185-190.
    • (1998) FEBS Lett , vol.433 , pp. 185-190
    • Kunzler, M.1    Hurt, E.C.2
  • 105
    • 0031774336 scopus 로고    scopus 로고
    • Cse1p is involved in export of yeast importin alpha from the nucleus
    • Solsbacher J, Maurer P, Bischoff FR, Schlenstedt G. Cse1p is involved in export of yeast importin alpha from the nucleus. Mol Cell Biol 1998;18:6805-6815.
    • (1998) Mol Cell Biol , vol.18 , pp. 6805-6815
    • Solsbacher, J.1    Maurer, P.2    Bischoff, F.R.3    Schlenstedt, G.4
  • 108
    • 77949523576 scopus 로고    scopus 로고
    • Dissecting the signaling events that impact classical nuclear import and target nuclear transport factors
    • Kodiha M, Tran D, Morogan A, Qian C, Stochaj U. Dissecting the signaling events that impact classical nuclear import and target nuclear transport factors. PLoS One 2009;4:e8420.
    • (2009) PLoS One , vol.4
    • Kodiha, M.1    Tran, D.2    Morogan, A.3    Qian, C.4    Stochaj, U.5
  • 109
    • 0027183972 scopus 로고
    • CSE1 and CSE2, two new genes required for accurate mitotic chromosome segregation in Saccharomyces cerevisiae
    • Xiao Z, McGrew JT, Schroeder AJ, Fitzgerald-Hayes M. CSE1 and CSE2, two new genes required for accurate mitotic chromosome segregation in Saccharomyces cerevisiae. Mol Cell Biol 1993;13:4691-4702.
    • (1993) Mol Cell Biol , vol.13 , pp. 4691-4702
    • Xiao, Z.1    McGrew, J.T.2    Schroeder, A.J.3    Fitzgerald-Hayes, M.4
  • 110
    • 0029033504 scopus 로고
    • Genes involved in sister chromatid separation are needed for B-type cyclin proteolysis in budding yeast
    • Irniger S, Piatti S, Michaelis C, Nasmyth K. Genes involved in sister chromatid separation are needed for B-type cyclin proteolysis in budding yeast. Cell 1995;81:269-278.
    • (1995) Cell , vol.81 , pp. 269-278
    • Irniger, S.1    Piatti, S.2    Michaelis, C.3    Nasmyth, K.4
  • 111
    • 43049147998 scopus 로고    scopus 로고
    • PHAPI, CAS, and Hsp70 promote apoptosome formation by preventing Apaf-1 aggregation and enhancing nucleotide exchange on Apaf-1
    • Kim HE, Jiang X, Du F, Wang X. PHAPI, CAS, and Hsp70 promote apoptosome formation by preventing Apaf-1 aggregation and enhancing nucleotide exchange on Apaf-1. Mol Cell 2008;30:239-247.
    • (2008) Mol Cell , vol.30 , pp. 239-247
    • Kim, H.E.1    Jiang, X.2    Du, F.3    Wang, X.4
  • 112
    • 0029911757 scopus 로고    scopus 로고
    • The human CAS protein which is homologous to the CSE1 yeast chromosome segregation gene product is associated with microtubules and mitotic spindle
    • Scherf U, Pastan I, Willingham MC, Brinkmann U. The human CAS protein which is homologous to the CSE1 yeast chromosome segregation gene product is associated with microtubules and mitotic spindle. Proc Natl Acad Sci U S A 1996;93:2670-2674.
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 2670-2674
    • Scherf, U.1    Pastan, I.2    Willingham, M.C.3    Brinkmann, U.4
  • 114
    • 34547956843 scopus 로고    scopus 로고
    • hCAS/CSE1L associates with chromatin and regulates expression of select p53 target genes
    • Tanaka T, Ohkubo S, Tatsuno I, Prives C. hCAS/CSE1L associates with chromatin and regulates expression of select p53 target genes. Cell 2007;130:638-650.
    • (2007) Cell , vol.130 , pp. 638-650
    • Tanaka, T.1    Ohkubo, S.2    Tatsuno, I.3    Prives, C.4
  • 116
    • 0347361541 scopus 로고    scopus 로고
    • Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs
    • Yi R, Qin Y, Macara IG, Cullen BR. Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs. Genes Dev 2003;17:3011-3016.
    • (2003) Genes Dev , vol.17 , pp. 3011-3016
    • Yi, R.1    Qin, Y.2    Macara, I.G.3    Cullen, B.R.4
  • 118
    • 1642499415 scopus 로고    scopus 로고
    • Exportin 5 is a RanGTP-dependent dsRNA-binding protein that mediates nuclear export of pre-miRNAs
    • Bohnsack MT, Czaplinski K, Gorlich D. Exportin 5 is a RanGTP-dependent dsRNA-binding protein that mediates nuclear export of pre-miRNAs. RNA 2004;10:185-191.
    • (2004) RNA , vol.10 , pp. 185-191
    • Bohnsack, M.T.1    Czaplinski, K.2    Gorlich, D.3
  • 124
    • 0031302226 scopus 로고    scopus 로고
    • Genetic and developmental analysis of mutant Ketel alleles that identify the Drosophila importin-beta homologue
    • Erdelyi M, Mathe E, Szabad J. Genetic and developmental analysis of mutant Ketel alleles that identify the Drosophila importin-beta homologue. Acta Biol Hung 1997;48:323-338.
    • (1997) Acta Biol Hung , vol.48 , pp. 323-338
    • Erdelyi, M.1    Mathe, E.2    Szabad, J.3
  • 125
    • 0034530384 scopus 로고    scopus 로고
    • The Ketel(D) dominant-negative mutations identify maternal function of the Drosophila importin-beta gene required for cleavage nuclei formation
    • Tirian L, Puro J, Erdelyi M, Boros I, Papp B, Lippai M, Szabad J. The Ketel(D) dominant-negative mutations identify maternal function of the Drosophila importin-beta gene required for cleavage nuclei formation. Genetics 2000;156:1901-1912.
    • (2000) Genetics , vol.156 , pp. 1901-1912
    • Tirian, L.1    Puro, J.2    Erdelyi, M.3    Boros, I.4    Papp, B.5    Lippai, M.6    Szabad, J.7
  • 126
    • 0035894382 scopus 로고    scopus 로고
    • Perturbing nuclear transport in Drosophila eye imaginal discs causes specific cell adhesion and axon guidance defects
    • Kumar JP, Wilkie GS, Tekotte H, Moses K, Davis I. Perturbing nuclear transport in Drosophila eye imaginal discs causes specific cell adhesion and axon guidance defects. Dev Biol 2001;240:315-325.
    • (2001) Dev Biol , vol.240 , pp. 315-325
    • Kumar, J.P.1    Wilkie, G.S.2    Tekotte, H.3    Moses, K.4    Davis, I.5
  • 127
    • 82455171980 scopus 로고    scopus 로고
    • Moleskin is essential for the formation of the myotendinous junction in Drosophila
    • Liu ZC, Geisbrecht ER. Moleskin is essential for the formation of the myotendinous junction in Drosophila. Dev Biol 2011;359:176-189.
    • (2011) Dev Biol , vol.359 , pp. 176-189
    • Liu, Z.C.1    Geisbrecht, E.R.2
  • 129
    • 33846513896 scopus 로고    scopus 로고
    • A genetic screen in Drosophila for genes interacting with senseless during neuronal development identifies the importin moleskin
    • Pepple KL, Anderson AE, Frankfort BJ, Mardon G. A genetic screen in Drosophila for genes interacting with senseless during neuronal development identifies the importin moleskin. Genetics 2007;175:125-141.
    • (2007) Genetics , vol.175 , pp. 125-141
    • Pepple, K.L.1    Anderson, A.E.2    Frankfort, B.J.3    Mardon, G.4
  • 130
    • 34547678501 scopus 로고    scopus 로고
    • Delta and Egfr expression are regulated by Importin-7/Moleskin in Drosophila wing development
    • Vrailas-Mortimer AD, Majumdar N, Middleton G, Cooke EM, Marenda DR. Delta and Egfr expression are regulated by Importin-7/Moleskin in Drosophila wing development. Dev Biol 2007;308:534-546.
    • (2007) Dev Biol , vol.308 , pp. 534-546
    • Vrailas-Mortimer, A.D.1    Majumdar, N.2    Middleton, G.3    Cooke, E.M.4    Marenda, D.R.5
  • 131
    • 33646678741 scopus 로고    scopus 로고
    • smoothened and thickveins regulate Moleskin/Importin 7-mediated MAP kinase signaling in the developing Drosophila eye
    • Vrailas AD, Marenda DR, Cook SE, Powers MA, Lorenzen JA, Perkins LA, Moses K. smoothened and thickveins regulate Moleskin/Importin 7-mediated MAP kinase signaling in the developing Drosophila eye. Development 2006;133:1485-1494.
    • (2006) Development , vol.133 , pp. 1485-1494
    • Vrailas, A.D.1    Marenda, D.R.2    Cook, S.E.3    Powers, M.A.4    Lorenzen, J.A.5    Perkins, L.A.6    Moses, K.7
  • 132
    • 2942708039 scopus 로고    scopus 로고
    • The moleskin gene product is essential for Caudal-mediated constitutive antifungal Drosomycin gene expression in Drosophila epithelia
    • Han SH, Ryu JH, Oh CT, Nam KB, Nam HJ, Jang IH, Brey PT, Lee WJ. The moleskin gene product is essential for Caudal-mediated constitutive antifungal Drosomycin gene expression in Drosophila epithelia. Insect Mol Biol 2004;13:323-327.
    • (2004) Insect Mol Biol , vol.13 , pp. 323-327
    • Han, S.H.1    Ryu, J.H.2    Oh, C.T.3    Nam, K.B.4    Nam, H.J.5    Jang, I.H.6    Brey, P.T.7    Lee, W.J.8
  • 133
    • 34548842261 scopus 로고    scopus 로고
    • Msk is required for nuclear import of TGF-beta/BMP-activated Smads
    • Xu L, Yao X, Chen X, Lu P, Zhang B, Ip YT. Msk is required for nuclear import of TGF-beta/BMP-activated Smads. J Cell Biol 2007;178:981-994.
    • (2007) J Cell Biol , vol.178 , pp. 981-994
    • Xu, L.1    Yao, X.2    Chen, X.3    Lu, P.4    Zhang, B.5    Ip, Y.T.6
  • 134
    • 77950987081 scopus 로고    scopus 로고
    • Importin-beta11 regulates synaptic phosphorylated mothers against decapentaplegic, and thereby influences synaptic development and function at the Drosophila neuromuscular junction
    • Higashi-Kovtun ME, Mosca TJ, Dickman DK, Meinertzhagen IA, Schwarz TL. Importin-beta11 regulates synaptic phosphorylated mothers against decapentaplegic, and thereby influences synaptic development and function at the Drosophila neuromuscular junction. J Neurosci 2010;30:5253-5268.
    • (2010) J Neurosci , vol.30 , pp. 5253-5268
    • Higashi-Kovtun, M.E.1    Mosca, T.J.2    Dickman, D.K.3    Meinertzhagen, I.A.4    Schwarz, T.L.5
  • 135
    • 77955058547 scopus 로고    scopus 로고
    • The nuclear import of Frizzled2-C by Importins-beta11 and alpha2 promotes postsynaptic development
    • Mosca TJ, Schwarz TL. The nuclear import of Frizzled2-C by Importins-beta11 and alpha2 promotes postsynaptic development. Nat Neurosci 2010;13:935-943.
    • (2010) Nat Neurosci , vol.13 , pp. 935-943
    • Mosca, T.J.1    Schwarz, T.L.2
  • 136
    • 65649106872 scopus 로고    scopus 로고
    • Importin 13 regulates neurotransmitter release at the Drosophila neuromuscular junction
    • Giagtzoglou N, Lin YQ, Haueter C, Bellen HJ. Importin 13 regulates neurotransmitter release at the Drosophila neuromuscular junction. J Neurosci 2009;29:5628-5639.
    • (2009) J Neurosci , vol.29 , pp. 5628-5639
    • Giagtzoglou, N.1    Lin, Y.Q.2    Haueter, C.3    Bellen, H.J.4
  • 137
    • 0033870081 scopus 로고    scopus 로고
    • The Drosophila embargoed gene is required for larval progression and encodes the functional homolog of Schizosaccharomyces Crm1
    • Collier S, Chan HY, Toda T, McKimmie C, Johnson G, Adler PN, O'Kane C, Ashburner M. The Drosophila embargoed gene is required for larval progression and encodes the functional homolog of Schizosaccharomyces Crm1. Genetics 2000;155:1799-1807.
    • (2000) Genetics , vol.155 , pp. 1799-1807
    • Collier, S.1    Chan, H.Y.2    Toda, T.3    McKimmie, C.4    Johnson, G.5    Adler, P.N.6    O'Kane, C.7    Ashburner, M.8
  • 138
    • 0032536820 scopus 로고    scopus 로고
    • Nuclear export of actin: a novel mechanism regulating the subcellular localization of a major cytoskeletal protein
    • Wada A, Fukuda M, Mishima M, Nishida E. Nuclear export of actin: a novel mechanism regulating the subcellular localization of a major cytoskeletal protein. EMBO J 1998;17:1635-1641.
    • (1998) EMBO J , vol.17 , pp. 1635-1641
    • Wada, A.1    Fukuda, M.2    Mishima, M.3    Nishida, E.4
  • 139
    • 0037091078 scopus 로고    scopus 로고
    • Dcas is required for importin-alpha3 nuclear export and mechano-sensory organ cell fate specification in Drosophila
    • Tekotte H, Berdnik D, Torok T, Buszczak M, Jones LM, Cooley L, Knoblich JA, Davis I. Dcas is required for importin-alpha3 nuclear export and mechano-sensory organ cell fate specification in Drosophila. Dev Biol 2002;244:396-406.
    • (2002) Dev Biol , vol.244 , pp. 396-406
    • Tekotte, H.1    Berdnik, D.2    Torok, T.3    Buszczak, M.4    Jones, L.M.5    Cooley, L.6    Knoblich, J.A.7    Davis, I.8
  • 140
    • 79960613149 scopus 로고    scopus 로고
    • Rice Importin beta1 gene affects pollen tube elongation
    • Han MJ, Jung KH, Yi G, An G. Rice Importin beta1 gene affects pollen tube elongation. Mol Cells 2011;31:523-530.
    • (2011) Mol Cells , vol.31 , pp. 523-530
    • Han, M.J.1    Jung, K.H.2    Yi, G.3    An, G.4
  • 141
    • 84880781422 scopus 로고    scopus 로고
    • An Arabidopsis homolog of importin beta1 is required for ABA response and drought tolerance
    • Luo Y, Wang Z, Ji H, Fang H, Wang S, Tian L, Li X. An Arabidopsis homolog of importin beta1 is required for ABA response and drought tolerance. Plant J 2013;75:377-389.
    • (2013) Plant J , vol.75 , pp. 377-389
    • Luo, Y.1    Wang, Z.2    Ji, H.3    Fang, H.4    Wang, S.5    Tian, L.6    Li, X.7
  • 142
    • 33747045183 scopus 로고    scopus 로고
    • Mutation of SAD2, an importin beta-domain protein in Arabidopsis, alters abscisic acid sensitivity
    • Verslues PE, Guo Y, Dong CH, Ma W, Zhu JK. Mutation of SAD2, an importin beta-domain protein in Arabidopsis, alters abscisic acid sensitivity. Plant J 2006;47:776-787.
    • (2006) Plant J , vol.47 , pp. 776-787
    • Verslues, P.E.1    Guo, Y.2    Dong, C.H.3    Ma, W.4    Zhu, J.K.5
  • 143
    • 79959831970 scopus 로고    scopus 로고
    • Transportin-SR is required for proper splicing of resistance genes and plant immunity
    • Xu S, Zhang Z, Jing B, Gannon P, Ding J, Xu F, Li X, Zhang Y. Transportin-SR is required for proper splicing of resistance genes and plant immunity. PLoS Genet 2011;7:e1002159.
    • (2011) PLoS Genet , vol.7
    • Xu, S.1    Zhang, Z.2    Jing, B.3    Gannon, P.4    Ding, J.5    Xu, F.6    Li, X.7    Zhang, Y.8
  • 144
    • 59449106729 scopus 로고    scopus 로고
    • Exportin1 genes are essential for development and function of the gametophytes in Arabidopsis thaliana
    • Blanvillain R, Boavida LC, McCormick S, Ow DW. Exportin1 genes are essential for development and function of the gametophytes in Arabidopsis thaliana. Genetics 2008;180:1493-1500.
    • (2008) Genetics , vol.180 , pp. 1493-1500
    • Blanvillain, R.1    Boavida, L.C.2    McCormick, S.3    Ow, D.W.4
  • 145
    • 77953925669 scopus 로고    scopus 로고
    • Isolation and characterization of the Arabidopsis heat-intolerant 2 (hit2) mutant reveal the essential role of the nuclear export receptor EXPORTIN1A (XPO1A) in plant heat tolerance
    • Wu SJ, Wang LC, Yeh CH, Lu CA. Isolation and characterization of the Arabidopsis heat-intolerant 2 (hit2) mutant reveal the essential role of the nuclear export receptor EXPORTIN1A (XPO1A) in plant heat tolerance. New Phytol 2010;186:833-842.
    • (2010) New Phytol , vol.186 , pp. 833-842
    • Wu, S.J.1    Wang, L.C.2    Yeh, C.H.3    Lu, C.A.4
  • 147
    • 0041464459 scopus 로고    scopus 로고
    • PAUSED, a putative exportin-t, acts pleiotropically in Arabidopsis development but is dispensable for viability
    • Li J, Chen X. PAUSED, a putative exportin-t, acts pleiotropically in Arabidopsis development but is dispensable for viability. Plant Physiol 2003;132:1913-1924.
    • (2003) Plant Physiol , vol.132 , pp. 1913-1924
    • Li, J.1    Chen, X.2
  • 148
    • 62849086403 scopus 로고    scopus 로고
    • Seizures increase importin-beta1 expression in NG2+ cells in the rat hippocampus
    • Brilli E, Scali M, Casarosa S, Kohler M, Bozzi Y. Seizures increase importin-beta1 expression in NG2+ cells in the rat hippocampus. J Neurosci Res 2009;87:636-643.
    • (2009) J Neurosci Res , vol.87 , pp. 636-643
    • Brilli, E.1    Scali, M.2    Casarosa, S.3    Kohler, M.4    Bozzi, Y.5
  • 150
    • 79954464577 scopus 로고    scopus 로고
    • Expanded polyglutamine domain possesses nuclear export activity which modulates subcellular localization and toxicity of polyQ disease protein via exportin-1
    • Chan WM, Tsoi H, Wu CC, Wong CH, Cheng TC, Li HY, Lau KF, Shaw PC, Perrimon N, Chan HY. Expanded polyglutamine domain possesses nuclear export activity which modulates subcellular localization and toxicity of polyQ disease protein via exportin-1. Hum Mol Genet 2011;20:1738-1750.
    • (2011) Hum Mol Genet , vol.20 , pp. 1738-1750
    • Chan, W.M.1    Tsoi, H.2    Wu, C.C.3    Wong, C.H.4    Cheng, T.C.5    Li, H.Y.6    Lau, K.F.7    Shaw, P.C.8    Perrimon, N.9    Chan, H.Y.10
  • 151
  • 156
    • 33845382332 scopus 로고    scopus 로고
    • Importin 13 regulates nuclear import of the glucocorticoid receptor in airway epithelial cells
    • Tao T, Lan J, Lukacs GL, Hache RJ, Kaplan F. Importin 13 regulates nuclear import of the glucocorticoid receptor in airway epithelial cells. Am J Respir Cell Mol Biol 2006;35:668-680.
    • (2006) Am J Respir Cell Mol Biol , vol.35 , pp. 668-680
    • Tao, T.1    Lan, J.2    Lukacs, G.L.3    Hache, R.J.4    Kaplan, F.5
  • 157
    • 70249091813 scopus 로고    scopus 로고
    • Importin-13 genetic variation is associated with improved airway responsiveness in childhood asthma
    • Raby BA, Van Steen K, Lasky-Su J, Tantisira K, Kaplan F, Weiss ST. Importin-13 genetic variation is associated with improved airway responsiveness in childhood asthma. Respir Res 2009;10:67.
    • (2009) Respir Res , vol.10 , pp. 67
    • Raby, B.A.1    Van Steen, K.2    Lasky-Su, J.3    Tantisira, K.4    Kaplan, F.5    Weiss, S.T.6
  • 160
    • 4544353977 scopus 로고    scopus 로고
    • The KPNB3 locus is associated with schizophrenia
    • Wei J, Hemmings GP. The KPNB3 locus is associated with schizophrenia. Neurosci Lett 2004;368:323-326.
    • (2004) Neurosci Lett , vol.368 , pp. 323-326
    • Wei, J.1    Hemmings, G.P.2
  • 162
    • 21444442419 scopus 로고    scopus 로고
    • The KPNA3 gene may be a susceptibility candidate for schizophrenia
    • Wei J, Hemmings GP. The KPNA3 gene may be a susceptibility candidate for schizophrenia. Neurosci Res 2005;52:342-346.
    • (2005) Neurosci Res , vol.52 , pp. 342-346
    • Wei, J.1    Hemmings, G.P.2
  • 165
    • 0036885134 scopus 로고    scopus 로고
    • CAS (cellular apoptosis susceptibility) gene expression in ovarian carcinoma: correlation with 20q13.2 copy number and cyclin D1, p53, and Rb protein expression
    • Peiro G, Diebold J, Lohrs U. CAS (cellular apoptosis susceptibility) gene expression in ovarian carcinoma: correlation with 20q13.2 copy number and cyclin D1, p53, and Rb protein expression. Am J Clin Pathol 2002;118:922-929.
    • (2002) Am J Clin Pathol , vol.118 , pp. 922-929
    • Peiro, G.1    Diebold, J.2    Lohrs, U.3
  • 166
    • 0742272522 scopus 로고    scopus 로고
    • Expression of cellular apoptosis susceptibility protein in serous ovarian carcinoma: a clinicopathologic and immunohistochemical study
    • Brustmann H. Expression of cellular apoptosis susceptibility protein in serous ovarian carcinoma: a clinicopathologic and immunohistochemical study. Gynecol Oncol 2004;92:268-276.
    • (2004) Gynecol Oncol , vol.92 , pp. 268-276
    • Brustmann, H.1
  • 170
    • 0031031691 scopus 로고    scopus 로고
    • Localization of the cell proliferation and apoptosis-associated CAS protein in lymphoid neoplasms
    • Wellmann A, Krenacs L, Fest T, Scherf U, Pastan I, Raffeld M, Brinkmann U. Localization of the cell proliferation and apoptosis-associated CAS protein in lymphoid neoplasms. Am J Pathol 1997;150:25-30.
    • (1997) Am J Pathol , vol.150 , pp. 25-30
    • Wellmann, A.1    Krenacs, L.2    Fest, T.3    Scherf, U.4    Pastan, I.5    Raffeld, M.6    Brinkmann, U.7
  • 172
    • 84871187925 scopus 로고    scopus 로고
    • Cellular apoptosis susceptibility (chromosome segregation 1-like, CSE1L) gene is a key regulator of apoptosis, migration and invasion in colorectal cancer
    • Alnabulsi A, Agouni A, Mitra S, Garcia-Murillas I, Carpenter B, Bird S, Murray GI. Cellular apoptosis susceptibility (chromosome segregation 1-like, CSE1L) gene is a key regulator of apoptosis, migration and invasion in colorectal cancer. J Pathol 2012;228:471-481.
    • (2012) J Pathol , vol.228 , pp. 471-481
    • Alnabulsi, A.1    Agouni, A.2    Mitra, S.3    Garcia-Murillas, I.4    Carpenter, B.5    Bird, S.6    Murray, G.I.7
  • 173
    • 0029965390 scopus 로고    scopus 로고
    • The human CAS (cellular apoptosis susceptibility) gene mapping on chromosome 20q13 is amplified in BT474 breast cancer cells and part of aberrant chromosomes in breast and colon cancer cell lines
    • Brinkmann U, Gallo M, Polymeropoulos MH, Pastan I. The human CAS (cellular apoptosis susceptibility) gene mapping on chromosome 20q13 is amplified in BT474 breast cancer cells and part of aberrant chromosomes in breast and colon cancer cell lines. Genome Res 1996;6:187-194.
    • (1996) Genome Res , vol.6 , pp. 187-194
    • Brinkmann, U.1    Gallo, M.2    Polymeropoulos, M.H.3    Pastan, I.4
  • 174
    • 0035149402 scopus 로고    scopus 로고
    • Implication of the proliferation and apoptosis associated CSE1L/CAS gene for breast cancer development
    • Behrens P, Brinkmann U, Fogt F, Wernert N, Wellmann A. Implication of the proliferation and apoptosis associated CSE1L/CAS gene for breast cancer development. Anticancer Res 2001;21:2413-2417.
    • (2001) Anticancer Res , vol.21 , pp. 2413-2417
    • Behrens, P.1    Brinkmann, U.2    Fogt, F.3    Wernert, N.4    Wellmann, A.5
  • 175
    • 0034796271 scopus 로고    scopus 로고
    • Cellular apoptosis susceptibility gene expression in endometrial carcinoma: correlation with Bcl-2, Bax, and caspase-3 expression and outcome
    • Peiro G, Diebold J, Baretton GB, Kimmig R, Lohrs U. Cellular apoptosis susceptibility gene expression in endometrial carcinoma: correlation with Bcl-2, Bax, and caspase-3 expression and outcome. Int J Gynecol Pathol 2001;20:359-367.
    • (2001) Int J Gynecol Pathol , vol.20 , pp. 359-367
    • Peiro, G.1    Diebold, J.2    Baretton, G.B.3    Kimmig, R.4    Lohrs, U.5
  • 177
    • 42149140616 scopus 로고    scopus 로고
    • Expression of the nuclear export protein chromosomal region maintenance/exportin 1/Xpo1 is a prognostic factor in human ovarian cancer
    • Noske A, Weichert W, Niesporek S, Roske A, Buckendahl AC, Koch I, Sehouli J, Dietel M, Denkert C. Expression of the nuclear export protein chromosomal region maintenance/exportin 1/Xpo1 is a prognostic factor in human ovarian cancer. Cancer 2008;112:1733-1743.
    • (2008) Cancer , vol.112 , pp. 1733-1743
    • Noske, A.1    Weichert, W.2    Niesporek, S.3    Roske, A.4    Buckendahl, A.C.5    Koch, I.6    Sehouli, J.7    Dietel, M.8    Denkert, C.9
  • 179
    • 67651176297 scopus 로고    scopus 로고
    • Expression of CRM1 in human gliomas and its significance in p27 expression and clinical prognosis
    • discussion 159-160.
    • Shen A, Wang Y, Zhao Y, Zou L, Sun L, Cheng C. Expression of CRM1 in human gliomas and its significance in p27 expression and clinical prognosis. Neurosurgery 2009;65:153-159 discussion 159-160.
    • (2009) Neurosurgery , vol.65 , pp. 153-159
    • Shen, A.1    Wang, Y.2    Zhao, Y.3    Zou, L.4    Sun, L.5    Cheng, C.6
  • 181
    • 62449215108 scopus 로고    scopus 로고
    • The Karyopherin proteins, Crm1 and Karyopherin beta1, are overexpressed in cervical cancer and are critical for cancer cell survival and proliferation
    • van der Watt PJ, Maske CP, Hendricks DT, Parker MI, Denny L, Govender D, Birrer MJ, Leaner VD. The Karyopherin proteins, Crm1 and Karyopherin beta1, are overexpressed in cervical cancer and are critical for cancer cell survival and proliferation. Int J Cancer 2009;124:1829-1840.
    • (2009) Int J Cancer , vol.124 , pp. 1829-1840
    • van der Watt, P.J.1    Maske, C.P.2    Hendricks, D.T.3    Parker, M.I.4    Denny, L.5    Govender, D.6    Birrer, M.J.7    Leaner, V.D.8
  • 182
    • 81455149500 scopus 로고    scopus 로고
    • Overexpression of Kpnbeta1 and Kpnalpha2 importin proteins in cancer derives from deregulated E2F activity
    • van der Watt PJ, Ngarande E, Leaner VD. Overexpression of Kpnbeta1 and Kpnalpha2 importin proteins in cancer derives from deregulated E2F activity. PLoS One 2011;6:e27723.
    • (2011) PLoS One , vol.6
    • van der Watt, P.J.1    Ngarande, E.2    Leaner, V.D.3
  • 184
    • 84872264446 scopus 로고    scopus 로고
    • Inducing cell proliferation inhibition and apoptosis via silencing Dicer, Drosha, and Exportin 5 in urothelial carcinoma of the bladder
    • Han Y, Liu Y, Gui Y, Cai Z. Inducing cell proliferation inhibition and apoptosis via silencing Dicer, Drosha, and Exportin 5 in urothelial carcinoma of the bladder. J Surg Oncol 2013;107:201-205.
    • (2013) J Surg Oncol , vol.107 , pp. 201-205
    • Han, Y.1    Liu, Y.2    Gui, Y.3    Cai, Z.4
  • 185
    • 84863548196 scopus 로고    scopus 로고
    • Increased expression of importin13 in endometriosis and endometrial carcinoma
    • Zeng B, Hu J, Yuan R, Hu L, Zhong L, Kang K. Increased expression of importin13 in endometriosis and endometrial carcinoma. Med Sci Monit 2012;18:CR361-CR367.
    • (2012) Med Sci Monit , vol.18
    • Zeng, B.1    Hu, J.2    Yuan, R.3    Hu, L.4    Zhong, L.5    Kang, K.6
  • 186
    • 83355163382 scopus 로고    scopus 로고
    • Importin beta1 protein-mediated nuclear localization of death receptor 5 (DR5) limits DR5/tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL)-induced cell death of human tumor cells
    • Kojima Y, Nakayama M, Nishina T, Nakano H, Koyanagi M, Takeda K, Okumura K, Yagita H. Importin beta1 protein-mediated nuclear localization of death receptor 5 (DR5) limits DR5/tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL)-induced cell death of human tumor cells. J Biol Chem 2011;286:43383-43393.
    • (2011) J Biol Chem , vol.286 , pp. 43383-43393
    • Kojima, Y.1    Nakayama, M.2    Nishina, T.3    Nakano, H.4    Koyanagi, M.5    Takeda, K.6    Okumura, K.7    Yagita, H.8
  • 187
    • 84882946051 scopus 로고    scopus 로고
    • Regulation of cell proliferation and migration by keratin19-induced nuclear import of early growth response-1 in breast cancer cells
    • Ju JH, Yang W, Lee KM, Oh S, Nam K, Shim S, Shin SY, Gye MC, Chu IS, Shin I. Regulation of cell proliferation and migration by keratin19-induced nuclear import of early growth response-1 in breast cancer cells. Clin Cancer Res 2013;19:4335-4346.
    • (2013) Clin Cancer Res , vol.19 , pp. 4335-4346
    • Ju, J.H.1    Yang, W.2    Lee, K.M.3    Oh, S.4    Nam, K.5    Shim, S.6    Shin, S.Y.7    Gye, M.C.8    Chu, I.S.9    Shin, I.10
  • 189
    • 79955858374 scopus 로고    scopus 로고
    • CRM1-dependent p53 nuclear accumulation in lung lesions of a bitransgenic mouse lung tumor model
    • Chen L, Moore JE, Samathanam C, Shao C, Cobos E, Miller MS, Gao W. CRM1-dependent p53 nuclear accumulation in lung lesions of a bitransgenic mouse lung tumor model. Oncol Rep 2011;26:223-228.
    • (2011) Oncol Rep , vol.26 , pp. 223-228
    • Chen, L.1    Moore, J.E.2    Samathanam, C.3    Shao, C.4    Cobos, E.5    Miller, M.S.6    Gao, W.7
  • 190
    • 84870570626 scopus 로고    scopus 로고
    • Inhibition of CRM1-mediated nucleocytoplasmic transport: triggering human melanoma cell apoptosis by perturbing multiple cellular pathways
    • Pathria G, Wagner C, Wagner SN. Inhibition of CRM1-mediated nucleocytoplasmic transport: triggering human melanoma cell apoptosis by perturbing multiple cellular pathways. J Invest Dermatol 2012;132:2780-2790.
    • (2012) J Invest Dermatol , vol.132 , pp. 2780-2790
    • Pathria, G.1    Wagner, C.2    Wagner, S.N.3
  • 196
    • 4344627104 scopus 로고    scopus 로고
    • Human topoisomerase IIalpha nuclear export is mediated by two CRM-1-dependent nuclear export signals
    • Turner JG, Engel R, Derderian JA, Jove R, Sullivan DM. Human topoisomerase IIalpha nuclear export is mediated by two CRM-1-dependent nuclear export signals. J Cell Sci 2004;117:3061-3071.
    • (2004) J Cell Sci , vol.117 , pp. 3061-3071
    • Turner, J.G.1    Engel, R.2    Derderian, J.A.3    Jove, R.4    Sullivan, D.M.5
  • 198
    • 42049104376 scopus 로고    scopus 로고
    • CSE1L/CAS, a microtubule-associated protein, inhibits taxol (paclitaxel)-induced apoptosis but enhances cancer cell apoptosis induced by various chemotherapeutic drugs
    • Liao CF, Luo SF, Shen TY, Lin CH, Chien JT, Du SY, Jiang MC. CSE1L/CAS, a microtubule-associated protein, inhibits taxol (paclitaxel)-induced apoptosis but enhances cancer cell apoptosis induced by various chemotherapeutic drugs. BMB Rep 2008;41:210-216.
    • (2008) BMB Rep , vol.41 , pp. 210-216
    • Liao, C.F.1    Luo, S.F.2    Shen, T.Y.3    Lin, C.H.4    Chien, J.T.5    Du, S.Y.6    Jiang, M.C.7
  • 199
    • 57349097228 scopus 로고    scopus 로고
    • CAS enhances chemotherapeutic drug-induced p53 accumulation and apoptosis: use of CAS for high-sensitivity anticancer drug screening
    • Liao CF, Luo SF, Tsai CS, Tsao TY, Chen SL, Jiang MC. CAS enhances chemotherapeutic drug-induced p53 accumulation and apoptosis: use of CAS for high-sensitivity anticancer drug screening. Toxicol Mech Methods 2008;18:771-776.
    • (2008) Toxicol Mech Methods , vol.18 , pp. 771-776
    • Liao, C.F.1    Luo, S.F.2    Tsai, C.S.3    Tsao, T.Y.4    Chen, S.L.5    Jiang, M.C.6
  • 201
    • 84871881617 scopus 로고    scopus 로고
    • Identification of cargo proteins specific for the nucleocytoplasmic transport carrier transportin by combination of an in vitro transport system and stable isotope labeling by amino acids in cell culture (SILAC)-based quantitative proteomics
    • Kimura M, Kose S, Okumura N, Imai K, Furuta M, Sakiyama N, Tomii K, Horton P, Takao T, Imamoto N. Identification of cargo proteins specific for the nucleocytoplasmic transport carrier transportin by combination of an in vitro transport system and stable isotope labeling by amino acids in cell culture (SILAC)-based quantitative proteomics. Mol Cell Proteomics 2013;12:145-157.
    • (2013) Mol Cell Proteomics , vol.12 , pp. 145-157
    • Kimura, M.1    Kose, S.2    Okumura, N.3    Imai, K.4    Furuta, M.5    Sakiyama, N.6    Tomii, K.7    Horton, P.8    Takao, T.9    Imamoto, N.10
  • 202
    • 84867784579 scopus 로고    scopus 로고
    • Quantitative proteomics reveals regulation of karyopherin subunit alpha-2 (KPNA2) and its potential novel cargo proteins in nonsmall cell lung cancer
    • Wang CI, Chien KY, Wang CL, Liu HP, Cheng CC, Chang YS, Yu JS, Yu CJ. Quantitative proteomics reveals regulation of karyopherin subunit alpha-2 (KPNA2) and its potential novel cargo proteins in nonsmall cell lung cancer. Mol Cell Proteomics 2012;11:1105-1122.
    • (2012) Mol Cell Proteomics , vol.11 , pp. 1105-1122
    • Wang, C.I.1    Chien, K.Y.2    Wang, C.L.3    Liu, H.P.4    Cheng, C.C.5    Chang, Y.S.6    Yu, J.S.7    Yu, C.J.8
  • 203
    • 84874638077 scopus 로고    scopus 로고
    • Identification of CRM1-dependent nuclear export cargos using quantitative mass spectrometry
    • Thakar K, Karaca S, Port SA, Urlaub H, Kehlenbach RH. Identification of CRM1-dependent nuclear export cargos using quantitative mass spectrometry. Mol Cell Proteomics 2013;12:664-678.
    • (2013) Mol Cell Proteomics , vol.12 , pp. 664-678
    • Thakar, K.1    Karaca, S.2    Port, S.A.3    Urlaub, H.4    Kehlenbach, R.H.5
  • 204
    • 84883141388 scopus 로고    scopus 로고
    • Identification of cargo proteins specific for importin-beta with importin-alpha applying a stable isotope labeling by amino acids in cell culture (SILAC)-based in vitro transport system
    • Kimura M, Okumura N, Kose S, Takao T, Imamoto N. Identification of cargo proteins specific for importin-beta with importin-alpha applying a stable isotope labeling by amino acids in cell culture (SILAC)-based in vitro transport system. J Biol Chem 2013;288:24540-24549.
    • (2013) J Biol Chem , vol.288 , pp. 24540-24549
    • Kimura, M.1    Okumura, N.2    Kose, S.3    Takao, T.4    Imamoto, N.5


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