Decreased expression of XPO4 is associated with poor prognosis in hepatocellular carcinoma

Journal of Gastroenterology and Hepatology (Australia)

Volumn 26, Issue 3, 2011, Pages 544-549

  Liang, Xiao ting ^a   Pan, Ke ^a   Chen, Min shan ^a   Li, Jian jun ^a   Wang, Hui ^a   Zhao, Jing jing ^a   Sun, Jian cong ^a   Chen, Yi bing ^a   Ma, Hai qing ^a   Wang, Qi jing ^a   Xia, Jian chuan ^a  

^a SUN YAT SEN UNIVERSITY CANCER CENTER   (China)

Author keywords

Exportin 4; Expression; Hepatocellular carcinoma; Prognosis

Indexed keywords

EXPORTIN 4; MESSENGER RNA; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; DOWN REGULATION; FEMALE; GENE SEQUENCE; GENETIC TRANSCRIPTION; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LIVER CELL; LIVER CELL CARCINOMA; LIVER RESECTION; MAJOR CLINICAL STUDY; MALE; OVERALL SURVIVAL; PATHOGENESIS; PRIORITY JOURNAL; PROGNOSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; REAL TIME POLYMERASE CHAIN REACTION; TUMOR VOLUME;

EID: 79951592100     PISSN: 08159319     EISSN: 14401746     Source Type: Journal    
DOI: 10.1111/j.1440-1746.2010.06434.x     Document Type: Article

References (15)

1. Kew MC. Epidemiology of hepatocellular carcinoma. Toxicology 2002; 181-182: 35-8.
2. Parkin DM, Bray F, Ferlay J, Pisani P. Global cancer statistics, 2002. CA Cancer J. Clin. 2005; 55: 74-108.
3. Aravalli RN, Steer CJ, Cressman EN. Molecular mechanisms of hepatocellular carcinoma. Hepatology 2008; 48: 2047-63.
4. Thorgeirsson SS, Lee JS, Grisham JW. Functional genomics of hepatocellular carcinoma. Hepatology 2006; 43: S145-50.
5. Zender L, Xue W, Zuber J etal. An oncogenomics-based in vivo RNAi screen identifies tumor suppressors in liver cancer. Cell 2008; 135: 852-64.
6. Midorikawa Y, Yamamoto S, Ishikawa S etal. Molecular karyotyping of human hepatocellular carcinoma using single-nucleotide polymorphism arrays. Oncogene 2006; 25: 5581-90.
7. Tjia WM, Hu L, Zhang MY, Guan XY. Characterization of rearrangements involving 4q, 13q and 16q in hepatocellular carcinoma cell lines using region-specific multiplex-FISH probes. Cancer Lett 2007; 250: 92-9.
8. Hertz S, Rothamel T, Skawran B etal. Losses of chromosome arms 4q, 8p, 13q and gain of 8q are correlated with increasing chromosomal instability in hepatocellular carcinoma. Pathobiology 2008; 75: 312-22.
9. Hashimoto T, Nakayama S, Fukkuhara T etal. The state of recurrence and the role of hepatectomy in hepatocellular carcinoma. Hepatogastroenterology 1994; 41: 144-9.
10. Kubo S, Tanaka H, Shuto T etal. Prognostic effects of causative virus in hepatocellular carcinoma according to the Japan integrated staging (JIS) score. J. Gastroenterol. 2005; 40: 972-9.
11. Shimozawa N, Hanazaki K. Longterm prognosis after hepatic resection for small hepatocellular carcinoma. J. Am. Coll. Surg. 2004; 198: 356-65.
12. Grazi GL, Cescon M, Ravaioli M etal. Liver resection for hepatocellular carcinoma in cirrhotics and noncirrhotics. Evaluation of clinicopathologic features and comparison of risk factors for long-term survival and tumour recurrence in a single centre. Aliment. Pharmacol. Ther. 2003; 17 (Suppl. 2): 119-29.
13. Poon RT, Fan ST, Ng IO, Wong J. Significance of resection margin in hepatectomy for hepatocellular carcinoma: a critical reappraisal. Ann. Surg. 2000; 231: 544-51.
14. Kondo K, Chijiiwa K, Makino I etal. Risk factors for early death after liver resection in patients with solitary hepatocellular carcinoma. J. Hepatobiliary Pancreat. Surg. 2005; 12: 399-404.
15. Makino Y, Yamanoi A, Kimoto T, El-Assal ON, Kohno H, Nagasue N. The influence of perioperative blood transfusion on intrahepatic recurrence after curative resection of hepatocellular carcinoma. Am. J. Gastroenterol. 2000; 95: 1294-300.