CSE1L/CAS, a microtubule-associated protein, inhibits taxol (paclitaxel)-induced apoptosis but enhances cancer cell apoptosis induced by various chemotherapeutic drugs

Journal of Biochemistry and Molecular Biology

Volumn 41, Issue 3, 2008, Pages 210-216

  Liao, Ching Fong ^a   Luo, Shue Fen ^b   Shen, Tzu Yun ^a   Lin, Chin Huang ^a   Chien, Jung Tsun ^a   Du, Shin Yi ^a   Jiang, Ming Chung ^a  

^a INSTITUTE OF CELLULAR AND ORGANISMIC BIOLOGY   (Taiwan)

^b CHANG GUNG UNIVERSITY COLLEGE OF MEDICINE   (Taiwan)

Author keywords

Apoptosis; Cancers; Chemotherapeutic drugs; Paclitaxel; Taxol

Indexed keywords

EID: 42049104376     PISSN: 12258687     EISSN: 02191024     Source Type: Journal    
DOI: 10.5483/bmbrep.2008.41.3.210     Document Type: Article

References (33)

1. Kai, G., Zhao, L., Zhang, L., Li, Z., Guo, B., Zhao, D., Sun, X., Miao, Z. and Tang, K. (2005) Characterization and expression profile analysis of a new cDNA encoding taxadiene synthase from taxus media. J. Biochem. Mol. Biol. 38, 668-675.
2. Mekhail, T. M. and Markman, M. (2002) Paclitaxel in cancer therapy. Expert Opin. Pharmacother. 3, 755-766.
3. Park, J. H. and Kim, T. H. (2005) Release of cytochrome c from isolated mitochondria by etoposide. J. Biochem. Mol. Biol. 38, 619-623.
4. Wang, S. and El-Deiry, W. S. (2004) The p53 pathway: targets for the development of novel cancer therapeutics. Cancer Treat. Res. 119, 175-187.
5. Debernardis, D., Sire, E. G., De Feudis, P., Vikhanskaya, F., Valenti, M., Russo, P., Parodi, S., D'Incalci, M. and Broggini, M. (1997) p53 status does not affect sensitivity of human ovarian cancer cell lines to paclitaxel. Cancer Res. 57, 870-874.
6. Gadducci, A., Cianci, C., Cosio, S., Carnino, F., Fanucchi, A., Buttitta, F., Conte, P. F. and Genazzani, A. R. (2000) p53 status is neither a predictive nor a prognostic variable in patients with advanced ovarian cancer treated with a paclitaxel-based regimen. Anticancer Res. 20, 4793-4799.
7. Reinecke, P., Kalinski, T., Mahotka, C., Schmitz, M., Dejosez, M., Gabbert, H. E. and Gerharz, C. D. (2005) Paclitaxel/Taxol sensitivity in human renal cell carcinoma is not determined by the p53 status. Cancer Lett. 222, 165-171.
8. Zhou, J. and Giannakakou, P. (2005) Targeting microtubules for cancer chemotherapy. Curr. Med. Chem. Anticancer Agents 5, 65-71.
9. Dumontet, C. and Sikic, B. I. (1999) Mechanisms of action of and resistance to antitubulin agents: microtubule dynamics, drug transport, and cell death. J. Clin. Oncol. 17, 1061-1070.
10. Manfredi, J. J. and Horwitz, S. B. (1984) Taxol: an antimitotic agent with a new mechanism of action. Pharmacol. Ther. 25, 83-125.
11. Yvon, A. M., Wadsworth, P. and Jordan, M. A. (1999) Taxol suppresses dynamics of individual microtubules in living human tumor cells. Mol. Biol. Cell 10, 947-959.
12. Tommasi, S., Mangia, A., Lacalamita, R., Bellizzi, A., Fedele, V., Chiriatti, A., Thomssen, C., Kendzierski, N., Latorre, A., Lorusso, V., Schittulli, F., Zito, F., Kavallaris., M. and Paradiso, A. (2007) Cytoskeleton and paclitaxel sensitivity in breast cancer: The role of beta-tubulins. Int. J. Cancer 120, 2078-2085.
13. Hari, M., Loganzo, F., Annable, T., Tan, X., Musto, S., Morilla, D. B., Nettles, J. H., Snyder, J. P. and Greenberger, L. M. (2006) Paclitaxel-resistant cells have a mutation in the paclitaxel-binding region of beta-tubulin (Asp26Glu) and less stable microtubules. Mol. Cancer Ther. 5, 270-278.
14. Li, H., Yuan, M. and Mao, T. (2007) AtMAP65-1 binds to tubulin dimers to promote tubulin assembly. J. Biochem. Mol. Biol. 40, 218-225.
15. Bhalla, K. N. (2003) Microtubule-targeted anticancer agents and apoptosis. Oncogene 22, 9075-9086.
16. Orr, G. A., Verdier-Pinard, P., McDaid, H. and Horwitz, S. B. (2003) Mechanisms of Taxol resistance related to microtubules. Oncogene 22, 7280-7295.
17. Brinkmann, U., Brinkmann, E. and Pastan, I. (1995) Expression cloning of cDNAs that renders cancer cells resistant to Pseudomonas and diphtheria toxin and immunotoxins. Mol. Med. 1, 206-216.
18. Izaguirre, M. F., Vergara, M. N. and Casco, V. H. (2006) CAS role in the brain apoptosis of Bufo arenarum induced by cypermethrin. Biocell 30, 309-320.
19. Jiang, M. C., Luo, S. F., Li, L. T., Lin, C. C., Du, S. Y., Lin, C. Y., Hsu, Y. W. and Liao, C. F. (2007a) Synergic CSE1L/CAS, TNFR-1, and p53 apoptotic pathways in combined interferon-gamma/adriamycin-induced apoptosis of Hep G2 hepatoma cells. J. Exp. Clin. Cancer Res. 26, 91- 99.
20. Behrens, P., Brinkmann, U. and Wellmann, A. (2003) CSE1L/CAS: its role in proliferation and apoptosis. Apoptosis 8, 39-44.
21. Seiden-Long, I. M., Brown, K. R., Shih, W., Wigle, D. A., Radulovich, N., Jurisica, I. and Tsao, M. S. (2006) Transcriptional targets of hepatocyte growth factor signaling and Ki-ras oncogene activation in colorectal cancer. Oncogene 25, 91-102.
22. Scherf, U., Pastan, I., Willingham, M. C. and Brinkmann, U. (1996) The human CAS protein which is homologous to the CSE1 yeast chromosome segregation gene product is associated with microtubules and mitotic spindle. Proc. Natl. Acad. Sci. U.S.A. 93, 2670-2674.
23. Stier, S., Totzke, G., Gruewald, E., Neuhaus, T., Fronhoffs, S., Schoneborn, S., Vetter, H. and Ko, Y. (2005) Identification of p54(nrb) and the 14-3-3 Protein HS1 as TNF-alpha-inducible genes related to cell cycle control and apoptosis in human arterial endothelial cells. J. Biochem. Mol. Biol. 38, 447-456.
24. Upadhyaya, K. R., Radha, K. S. and Madhyastha, H. K. (2007) Cell cycle regulation and induction of apoptosis by beta-carotene in U937 and HL-60 leukemia cells. J. Biochem. Mol. Biol. 40, 1009-1015.
25. Faried, A., Faried, L. S., Kimura, H., Sohda, M., Nakajima, M., Miyazaki, T., Kato, H., Kanuma, T. and Kuwano, H. (2006) Differential sensitivity of paclitaxel-induced apoptosis in human esophageal squamous cell carcinoma cell lines. Cancer Chemother. Pharmacol. 57, 301-308.
26. Banerjee, S., Fallis, A. G. and Brown, D. L. (1997) Differential effects of taxol on two human cancer cell lines. Oncol. Res. 9, 237-248.
27. Rowinsky, E. K., Donehower, R. C. and Jones, R. J. (1988) Microtubule changes and cytotoxicity in leukemic cell lines treated with taxol. Cancer Res. 48, 4093-4100.
28. Fattman, C. L., An, B., Sussman, L. and Dou, Q. P. (1998) p53-independent dephosphorylation and cleavage of retinoblastoma protein during tamoxifen-induced apoptosis in human breast carcinoma cells. Cancer Lett. 130, 103-113.
29. Shajahan, A. N., Wang, A., Decker, M., Minshall, R. D., Liu, M. C. and Clarke, R. (2007) Caveolin-1 tyrosine phosphorylation enhances paclitaxel-mediated cytotoxicity. J. Biol. Chem. 282, 5934-5943.
30. Wagner, P., Wang, B., Clark, E., Lee, H., Rouzier, R. and Pusztai, L. (2005) Microtubule associated protein (MAP)-tau: a novel mediator of paclitaxel sensitivity in vitro and in vivo. Cell Cycle 4, 1149-1152.
31. Thommesen, L. and Laegreid, A. (2005) Distinct differences between TNF receptor 1- and TNF receptor 2-mediated activation of NFkappaB. J. Biochem. Mol. Biol. 38, 281-289.
32. Jiang, M. C., Liao, C. F. and Tai, C. C. (2002) CAS/CSE 1 stimulates E-cadhrin-dependent cell polarity in HT-29 human colon epithelial cells. Biochem. Biophys. Res. Commun. 294, 900-905.
33. Jiang, M. C., Jiang, P. C., Liao, C. F. and Lee, C. C. (2005) A modified mutation detection method for large-scale cloning of the possible single nucleotide polymorphism sequences. J. Biochem. Mol. Biol. 38, 191-197.