Heat-shock induced nuclear retention and recycling inhibition of importin α

Genes to Cells

Volumn 9, Issue 5, 2004, Pages 429-441

  Furuta, Maiko ^a,b   Kose, Shingo ^a   Koike, Makiko ^a   Shimi, Takeshi ^c   Hiraoka, Yasushi ^c   Yoneda, Yoshihiro ^b   Haraguchi, Tokuko ^c   Imamoto, Naoko ^a  

^a Discovery Research Institute   (Japan)

^b OSAKA UNIVERSITY   (Japan)

^c JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

HEAT SHOCK COGNATE PROTEIN 70; KARYOPHERIN ALPHA; KARYOPHERIN BETA;

ADAPTATION; ARTICLE; BIOACCUMULATION; BIOCHEMISTRY; CELL NUCLEUS; CELL TRANSPORT; CONTROLLED STUDY; CYTOLOGY; DOWN REGULATION; ENVIRONMENTAL FACTOR; FLUORESCENCE RECOVERY AFTER PHOTOBLEACHING; HEAT SHOCK; HELA CELL; HUMAN; HUMAN CELL; MOLECULAR SIZE; NUCLEOCYTOPLASMIC TRANSPORT; PRIORITY JOURNAL; PROTEIN TRANSPORT; REGULATORY MECHANISM; STATISTICAL SIGNIFICANCE; UPREGULATION;

ALPHA KARYOPHERINS; BETA KARYOPHERINS; CELL NUCLEUS; DOWN-REGULATION; FLUORESCENT ANTIBODY TECHNIQUE; HEAT-SHOCK RESPONSE; HELA CELLS; HUMANS; NUCLEAR LOCALIZATION SIGNALS; PROTEIN TRANSPORT;

EUKARYOTA;

EID: 2942654971     PISSN: 13569597     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1356-9597.2004.00734.x     Document Type: Article

References (39)

1. Adam, S.A. & Gerace, L. (1991) Cytosolic proteins that specifically bind nuclear location signals are receptors for nuclear import. Cell 66, 837-847.
2. Agard, D.A., Hiraoka, Y., Shaw, P. & Sedat, J.W (1989) Fluorescence microscopy in three dimensions. Method. Cell Biol. 30, 353-377.
3. Azuma, Y., Takio, K., Tabb, M.M., Vu, L. & Nomura, M. (1997) Phosphorylation of Srp1p, the yeast nuclear localization signal receptor, in vitro and in vivo. Biochimie 79, 247-259.
4. Bannister, A.J., Miska, E.A., Görlich, D. & Kouzarides, T. (2000) Acetylation of importin-alpha nuclear import factors by CBP/p300. Curr. Biol. 10, 467-470.
5. Conti, E., Uy, M., Leighton, L., Blobel, G. & Kuriyan, J. (1998) Crystallographic analysis of the recognition of a muclear localization signal by the nuclear import factor karyopherin α. Cell 94, 193-204.
6. Czubryt, M.P., Austria, J.A. & Pierce, G.N. (2000) Hydrogen peroxide inhibition of nuclear protein import is mediated by the mitogen-activated protein kinase, ERK2. J. Cell Biol. 148, 7-16.
7. Fang, X., Chen, T., Tran, K. & Parker, C.S. (2001) Developmental regulation of the heat shock response by nuclear transport factor karyopherin-alpha3. Development 128, 3349-3358.
8. Geles, K.G. & Adam, S.A. (2001) Germline and developmental roles of the nuclear transport factor importin α3 in C. elegans. Development 128, 1817-1830.
9. Görlich, D., Henklein, P., Laskey, R.A. & Hartmann, E. (1996) A 41 amino acid motif in importin-alpha confers binding to importin-beta and hence transit into the nucleus. EMBO J. 15, 1810-1817.
10. Görlich, D. & Kutay, U (1999) Transport between the cell nucleus and the cytoplasm Annu. Rev. Cell Dev. Biol. 15, 607-660.
11. Görlich, D., Prehn, S., Laskey, R.A. & Hartmann, E. (1994) Isolation of a protein that is essential for the first step of nuclear protein import. Cell 79, 767-778.
12. Haraguchi, T., Kaneda, T. & Hiraoka, Y. (1997) Dynamics of chromosomes and microtubules visualized by multiple-wavelength fluorescence imaging in living mammalian cells: effects of mitotic inhibitors on cell cycle progression. Genes Cells 2, 369-380.
13. Herold, A., Truant, R., Wiegand, H. & Cullen, B.R. (1998) Determination of the functional domain organization of the importin α nuclear import factor. J. Cell Biol. 143, 309-318.
14. Hieda, M., Tachibana, T., Yokoya, F., Kose, S., Imamoto, N. & Yoneda, Y. (1999) A monoclonal antibody to the COOH-terminal acidic portion of Ran inhibits both the recycling of Ran and nuclear protein import in living cells. J. Cell Biol. 144, 645-655.
15. Imamoto, N. (2000) Diversity in nucleocytoplasmic transport pathways. Cell Struct. Func. 25, 207-216.
16. Imamoto, N., Matsuoka, Y., Kurihara, T., et al. (1992) Antibodies against 70-kD heat shock cognate protein inhibit mediated nuclear import of karyophilic proteins. J. Cell Biol. 119, 1047-1061.
17. Imamoto, N., Shimamoto, T., Takao, T., et al. (1995a) In vivo evidence for involvemenet of a 58kDa component of nuclear pore-targeting complex in nuclear protein import. EMBO J. 14, 3617-3626.
18. Imamoto, N., Tachibana, T., Matsubae, M. & Yoneda, Y. (1995b) A karyophilic protein forms a stable complex with cytoplasmic components prior to nuclear pore binding. J. Biol. Chem. 270, 8559-8565.
19. Jans, D.A., Xiao, C.Y. & Lam, M.H. (2000) Nuclear targeting signal recognition: a key control point in nuclear transport? Bioessays 22, 532-544.
20. Kamei, Y., Yuba, S., Nakayama, T. & Yoneda, Y. (1999) Three distinct classes of the alpha-subunit of the nuclear pore-targeting complex (importin-alpha) are differentially expressed in adult mouse tissues. J. Histochem. Cytochem. 47, 363-372.
21. Kohler, M., Speck, C., Christiansen, M., et al. (1999) Evidence for distinct substrate specificities of importin alpha family members in nuclear protein import. Mol. Cell. Biol. 19, 7782-7791.
22. Kuhl, N.M. & Rensing, L. (2000) Heat shock effects on cell cycle progression. Cell. Mol. Life Sci. 57, 450-463. Review.
23. Kutay, U., Bischoff, F.R., Kostka, S., Kraft, R. & Görlich, D. (1997) Export of importin α from the nucleus is mediated by a specific nuclear transport factor. Cell 90, 1061-1071.
24. Macara, I. G. (2001) Transport into and out of the nucleus. Microbiol. Mol. Biol. Rev. 65, 670-594.
25. Matsusaka, T., Imamoto, N., Yoneda, Y. & Yanagida, M. (1998) Mutations in fission yeast Cut15, an importin alpha homolog, lead to mitotic progression without chromosome condensation. Curr. Biol. 8, 1031-1034.
26. Miyamoto, Y., Imamoto, N., Sekimoto, T., et al. (1997) Differential modes of nuclear localization signal (NLS) recognition by three distinct classes of NLS receptors. J. Biol. Chem. 272, 26375-26381.
27. Moore, J.D., Yang, J., Truant, R. & Kornbluth, S. (1999) Nuclear import of Cdk/cyclin complexes: identification of distinct mechanisms for import of Cdk2/cyclin E and Cdc2/cyclin B1. J. Cell Biol. 144, 213-224.
28. Nadler, S.G., Tritschler, D., Haffar, O.K., Blake, J., Bruce, A.G. & Cleaveland. J. S. (1997) Differential expression and sequence - specific interaction of karyopherin with nuclear localization sequences. J. Biol. Chem. 272, 4310-4315.
29. Phair, R.D. & Misteli, T. (2000) High mobility of proteins in the mammalian cell nucleus. Nature 404, 604-609.
30. Sekimoto, T., Imamoto, N., Nakajima, K., Hirano, T. & Yoneda, Y. (1997) Extracellular signal-dependent nuclear import of Stat1 is mediated by nuclear pore-targeting complex formation with NPI-1, but not Rch1. EMBO J. 16, 7067-7077.
31. Stochaj, U., Rassadi, R. & Chiu, J. (2000) Stress-mediated inhibition of the classical nuclear protein import pathway and nuclear accumulation of the small GTPase Gsp1p. FASEB J. 14, 2130-2132.
32. Tachibana, T., Hieda, M., Miyamoto, Y., Kose, S., Imamoto, N. & Yoneda, Y. (2000) Recycling of importin α from the nucleus is suppressed by loss of RCC1 function in living mammalian cells. Cell Struct. Funct. 25, 115-123.
33. Takagi, M., Matsuoka, Y., Kurihara, T. & Yoneda, Y. (1999) Chmadrin: a novel Ki-67 antigen-related perichromosomal protein possibly implicated in higher order chromatin structure. J. Cell Sci. 112, 2463-2472.
34. Weis, K. (2003) Regulating access to the genome: Nucleocytoplasmic the cell cycle. Cell 112, 441-451.
35. Weis, K., Ryder, U. & Lamond, A.I. (1996) The conserved N-terminal domain of hSRP1 is essential for nuclear protein import. EMBO J. 15, 1818-1825.
36. Welch, W.J. & Feramisco, J.R. (1984) Nuclear and nucleolar localization of the 72 000-dalton heat shock protein in heat-shocked mammalian cells. J. Biol. Chem. 259, 4501-4513.
37. Yano, R., Oakes, M.L., Tabb, M.M. & Nomura, M. (1994) Yeast Srp1p has homology to armadillo/plakoglobin/beta-catenin and participates in apparently multiple nuclear functions including the maintenance of the nucleolar structure. Proc. Narl. Acad. Sci. USA 91, 6880-6884.
38. Yokoya, F., Imamoto, N., Tachibana, T. & Yoneda, Y. (1999) β-catenin can be transported into the nucleus in a Ran-unassisted manner. Mol. Biol. Cell 10, 1119-1131.
39. Yoneda, Y. (2000) Nucleocytoplasmic protein traffic and its significance to cell function. Genes Cells 5, 777-787.