Genetic and developmental analysis of mutant Ketel alleles that identify the Drosophila importin-β homologue

Acta Biologica Hungarica

Volumn 48, Issue 3, 1997, Pages 323-338

  Erdelyi M ^a   Mathe E ^b   Szabad, J ^b  

^a INSTITUTE OF EXPERIMENTAL MEDICINE   (Hungary)

^b UNIVERSITY OF SZEGED   (Hungary)

Author keywords

Drosophila; Female sterility; Maternal effect; Nuclear protein import; Zygotic lethality

Indexed keywords

INSECT PROTEIN; KARYOPHERIN; NUCLEAR PROTEIN;

ALLELE; ANIMAL; ARTICLE; CHEMISTRY; DOMINANT GENE; DROSOPHILA MELANOGASTER; FEMALE; FEMALE INFERTILITY; GENE; GENETICS; GROWTH, DEVELOPMENT AND AGING; MALE; MITOSIS SPINDLE; MUTATION; PHENOTYPE; PHYSIOLOGY; PRENATAL DEVELOPMENT; PROTEIN CONFORMATION; RECESSIVE GENE; TEMPERATURE;

ALLELES; ANIMALS; DROSOPHILA MELANOGASTER; FEMALE; GENES, DOMINANT; GENES, INSECT; GENES, RECESSIVE; INFERTILITY, FEMALE; INSECT PROTEINS; KARYOPHERINS; MALE; MITOTIC SPINDLE APPARATUS; MUTATION; NUCLEAR PROTEINS; PHENOTYPE; PROTEIN CONFORMATION; TEMPERATURE;

EID: 0031302226     PISSN: 02365383     EISSN: None     Source Type: Journal    
DOI: 10.1007/bf03543204     Document Type: Article

References (29)

1. Anderson, K. (1995) One signal, two body axes. Science 269, 489-490.
2. Choller, R., Anderson, L. L. (1977) Conformational changes associated with the reversible cold inactivation of ribulose-1,5-bisphosphate carboxylase-oxygenase. Biochim. Biophys. Acta 482, 228-240.
3. Dasso, M., Seki, T., Azuma, Y., Ohba, T., Nishimoto, T. (1994) A mutant form of the Ran/TC4 protein disrupts nuclear function in Xenopus laevis egg extracts by inhibiting the RCC1 protein, a regulator of chromosome condensation. EMBO J. 13, 5732-5744.
4. Demeter, J., Morphew, M., Sazer, S. (1995) A mutation in the RCC1-related protein piml results in nuclear envelope fragmentation in fission yeast. Proc. Natl. Acad. Sci. USA 28, 1436-1440.
5. Erdélyi, M., Szabad, J. (1989) Isolation and characterization of dominant female sterile mutations of Drosophila melanogaster. I. Mutations on the third chromosome. Genetics 122, 111-127.
6. Foe, V. E., Odell, G. M., Edgar, B. A. (1993) Mitosis and morphogenesis in the Drosophila embryo: point and counterpoint. In: Bate, M., Martinez-Arias, A. (eds) The Development of Drosophila melanogaster. Cold Spring Harbor Laboratory Press, New York, pp. 149-300.
7. Görlich, D., Mattaj, I. W. (1996) Nucleocytoplasmic transport. Science 271, 1513-1518.
8. Görlich, D., Prehn, S., Laskey, R. A., Hartmann, E. (1994) Isolation of protein that is essential from the first step of nuclear protein import. Cell 79, 767-778.
9. González-Reyes, A., Elliot, H., St. Johnston, D. (1995) Polarization of both major body axes in Drosophila by gurken-torpedo signalling. Nature 375, 654-658.
10. Jürgens, G. (1987) Segmental organisation of the tail region in the embryo of Drosophila melanogaster. A blastoderm fate map of the cuticle structures of the larval tail region. Roux's Arch. Dev. Biol. 196, 141-157.
11. Jürgens, G., Lehmann, R., Schardin, M., Nüsslein-Volhard, C. (1986) Segmental organisation of the head in the embryo of Drosophila melanogaster. Roux's Arch. Dev. Biol. 195, 359-377.
12. Kornblut, S., Dasso, M., Newport, J. (1994) Evidence for a dual role for TC4 protein in regulating nuclear structure and cell cycle progression. J. Cell Biol. 125, 705-719.
13. Kussel, P., Frasch, M. (1995) Pendulin, a Drosophila protein with cell cycle-dependent nuclear localization, is required for normal cell proliferation. J. Cell Sci. 129, 1491-1507.
14. Lindsley, D. L., Zimm, G. G. (1992) The Genome of Drosophila melanogaster. Academic Press, San Diego and London.
15. Lippai, M., Mihály, J., Erdélyi, M., Máthé, E., Puro, J., Belecz, I., Tirian, L., Pósfai, J., Udvardy, A., Boros, I., Szabad, J. (1987) The Ketel gene encodes the Drosophila homologue of importin 90. (Submitted for publication.)
16. Montell, D. J., Keshishian, H., Spradling, A. C. (1991) Laser ablation studies of the role of the Drosophila oocyte nucleus in pattern formation. Science 254, 290-293.
17. Panté, N., Aebi, U. (1996) Toward molecular dissection of protein import into nuclei. Current Opinion in Cell Biology 8, 397-406.
18. Perrimon, N., Mahowald, A. P. (1986) Maternal role of zygotic lethals during early embryogenesis in Drosophila. In: Gametogenesis and the Early Embryo. A. R. Liss Inc., New York, pp. 221-235.
19. Powers, M. A., Forbes, D. J. (1984) Cytosolic factors in nuclear transport: what is importin? Cell 79, 931-934.
20. Rexach, M., Blobel, G. (1995) Protein import into nuclei: association and dissociation reactions involving transport substrate, transport factors and nucleoporins. Cell 83, 683-692.
21. Schlenstedt, G. (1996) Protein import into the nucleus. FEBS Letters 389, 75-79.
22. Schüpbach, T. (1987) Germ line and soma cooperate during oogenesis to establish the dorsoventral pattern of egg shell and embryo in Drosophila melanogaster. Cell 49, 699-707.
23. Schüpbach, T., Roth, S. (1994) Dorsoventral patterning in Drosophila oogenesis. Current Biol. 4, 502-507.
24. Schüpbach, T., Wieschaus, E. (1989) Female sterile mutations on the second chromosome of Drosophila melanogaster. 1. Maternal effect mutations. Genetics 121, 101-117.
25. Szabad, J., Erdélyi, M., Hoffmann, G., Szidonya, J., Wright, T. R. F. (1939) Isolation and characterization of dominant female sterile mutations of Drosophila melanogaster. II. Mutations on the second chromosome. Genetics 122, 823-835.
26. Török, I., Strand, D., Schmitt, R., Tick, G., Török, T., Kiss, I., Mechler, B. M. (1995) The overgrown hematopoietic organs-31 tumor suppressor gene of Drosophila encodes an importin-like protein accumulating in the nucleus at the onset of mitosis. J. Cell Biol. 129, 1473-1489.
27. Tricoire, H. (1988) Dominant maternal interactions with Drosophila segmentation genes. Wilhelm Roux's Arch. Dev. Biol. 197, 115-123.
28. Wieschaus, E. (1996) Embryonic transcription and the control of developmental pathways. Genetics 142, 5-10.
29. Wieschaus, E., Nüsslein-Volhard, C. (1986) Looking at embryos. In: Roberts, D. B. (ed.) Drosophila a Practical Approach. I.R.L. Press, Oxford, pp. 199-227.