Hikeshi, a nuclear import carrier for Hsp70s, protects cells from heat shock-induced nuclear damage

Cell

Volumn 149, Issue 3, 2012, Pages 578-589

  Kose, Shingo ^a   Furuta, Maiko ^a   Imamoto, Naoko ^a  

^a RIKEN   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; CARRIER PROTEIN; HEAT SHOCK PROTEIN 70; PROTEIN HIKESHI; UNCLASSIFIED DRUG;

ARTICLE; CELL DAMAGE; CELL PROTECTION; CELL VIABILITY; HEAT SHOCK; HEAT STRESS; HUMAN; HUMAN CELL; NUCLEAR IMPORT; PHENOTYPE; PRIORITY JOURNAL; PROTEIN TRANSPORT; T CELL DEPLETION;

EID: 84860323242     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2012.02.058     Document Type: Article

References (34)

1. J. Cotto, S. Fox, and R. Morimoto HSF1 granules: a novel stress-induced nuclear compartment of human cells J. Cell Sci. 110 1997 2925 2934 (Pubitemid 28005808)
2. M.P. Czubryt, J.A. Austria, and G.N. Pierce Hydrogen peroxide inhibition of nuclear protein import is mediated by the mitogen-activated protein kinase, ERK2 J. Cell Biol. 148 2000 7 16
3. D.P. Denning, S.S. Patel, V. Uversky, A.L. Fink, and M. Rexach Disorder in the nuclear pore complex: the FG repeat regions of nucleoporins are natively unfolded Proc. Natl. Acad. Sci. USA 100 2003 2450 2455 (Pubitemid 36297519)
4. R. Fernández-Valdivia, Y. Zhang, S. Pai, M.L. Metzker, and A. Schumacher l7Rn6 encodes a novel protein required for clara cell function in mouse lung development Genetics 172 2006 389 399 (Pubitemid 43345500)
5. M. Furuta, S. Kose, M. Koike, T. Shimi, Y. Hiraoka, Y. Yoneda, T. Haraguchi, and N. Imamoto Heat-shock induced nuclear retention and recycling inhibition of importin α Genes Cells 9 2004 429 441 (Pubitemid 38771933)
6. D. Görlich, and U. Kutay Transport between the cell nucleus and the cytoplasm Annu. Rev. Cell Dev. Biol. 15 1999 607 660 (Pubitemid 32250388)
7. L.C. Hancock, R.P. Behta, and J.M. Lopes Genomic analysis of the Opi- phenotype Genetics 173 2006 621 634
8. H. Hattori, T. Kaneda, B. Lokeshwar, A. Laszlo, and K. Ohtsuka A stress-inducible 40 kDa protein (hsp40): purification by modified two-dimensional gel electrophoresis and co-localization with hsc70(p73) in heat-shocked HeLa cells J. Cell Sci. 104 1993 629 638 (Pubitemid 23123456)
9. P. Kaláb, A. Pralle, E.Y. Isacoff, R. Heald, and K. Weis Analysis of a RanGTP-regulated gradient in mitotic somatic cells Nature 440 2006 697 701
10. H.H. Kampinga, and E.A. Craig The HSP70 chaperone machinery: J proteins as drivers of functional specificity Nat. Rev. Mol. Cell Biol. 11 2010 579 592
11. J.B. Kelley, and B.M. Paschal Hyperosmotic stress signaling to the nucleus disrupts the Ran gradient and the production of RanGTP Mol. Biol. Cell 18 2007 4365 4376 (Pubitemid 350060165)
12. M. Kodiha, A. Chu, N. Matusiewicz, and U. Stochaj Multiple mechanisms promote the inhibition of classical nuclear import upon exposure to severe oxidative stress Cell Death Differ. 11 2004 862 874 (Pubitemid 39139745)
13. M. Kodiha, D. Tran, A. Morogan, C. Qian, and U. Stochaj Dissecting the signaling events that impact classical nuclear import and target nuclear transport factors PLoS ONE 4 2009 e8420
14. H. Kosako, N. Yamaguchi, C. Aranami, M. Ushiyama, S. Kose, N. Imamoto, H. Taniguchi, E. Nishida, and S. Hattori Phosphoproteomics reveals new ERK MAP kinase targets and links ERK to nucleoporin-mediated nuclear transport Nat. Struct. Mol. Biol. 16 2009 1026 1035
15. S. Kose, N. Imamoto, T. Tachibana, T. Shimamoto, and Y. Yoneda Ran-unassisted nuclear migration of a 97-kD component of nuclear pore-targeting complex J. Cell Biol. 139 1997 841 849
16. S. Kose, N. Imamoto, T. Tachibana, M. Yoshida, and Y. Yoneda β-subunit of nuclear pore-targeting complex (importin-β) can be exported from the nucleus in a Ran-independent manner J. Biol. Chem. 274 1999 3946 3952
17. V. Lamian, G.M. Small, and C.M. Feldherr Evidence for the existence of a novel mechanism for the nuclear import of Hsc70 Exp. Cell Res. 228 1996 84 91 (Pubitemid 26349716)
18. M.P. Mayer Gymnastics of molecular chaperones Mol. Cell 39 2010 321 331
19. A.A. Michels, B. Kanon, A.W. Konings, K. Ohtsuka, O. Bensaude, and H.H. Kampinga Hsp70 and Hsp40 chaperone activities in the cytoplasm and the nucleus of mammalian cells J. Biol. Chem. 272 1997 33283 33289 (Pubitemid 28023677)
20. Y. Miyamoto, T. Saiwaki, J. Yamashita, Y. Yasuda, I. Kotera, S. Shibata, M. Shigeta, Y. Hiraoka, T. Haraguchi, and Y. Yoneda Cellular stresses induce the nuclear accumulation of importin α and cause a conventional nuclear import block J. Cell Biol. 165 2004 617 623 (Pubitemid 38765763)
21. M.V. Nachury, and K. Weis The direction of transport through the nuclear pore can be inverted Proc. Natl. Acad. Sci. USA 96 1999 9622 9627 (Pubitemid 29398781)
22. S. Nakielny, and G. Dreyfuss Import and export of the nuclear protein import receptor transportin by a mechanism independent of GTP hydrolysis Curr. Biol. 8 1998 89 95 (Pubitemid 28104521)
23. S.S. Patel, and M.F. Rexach Discovering novel interactions at the nuclear pore complex using bead halo: a rapid method for detecting molecular interactions of high and low affinity at equilibrium Mol. Cell. Proteomics 7 2008 121 131 (Pubitemid 351248238)
24. H.R. Pelham Hsp70 accelerates the recovery of nucleolar morphology after heat shock EMBO J. 3 1984 3095 3100
25. K. Ribbeck, and D. Görlich The permeability barrier of nuclear pore complexes appears to operate via hydrophobic exclusion EMBO J. 21 2002 2664 2671 (Pubitemid 34619382)
26. K. Richter, M. Haslbeck, and J. Buchner The heat shock response: life on the verge of death Mol. Cell 40 2010 253 266
27. Y. Shi, D.D. Mosser, and R.I. Morimoto Molecular chaperones as HSF1-specific transcriptional repressors Genes Dev. 12 1998 654 666 (Pubitemid 28134298)
28. M. Stewart Molecular mechanism of the nuclear protein import cycle Nat. Rev. Mol. Cell Biol. 8 2007 195 208
29. C. Strambio-De-Castillia, M. Niepel, and M.P. Rout The nuclear pore complex: bridging nuclear transport and gene regulation Nat. Rev. Mol. Cell Biol. 11 2010 490 501
30. J.M. Velazquez, and S. Lindquist hsp70: nuclear concentration during environmental stress and cytoplasmic storage during recovery Cell 36 1984 655 662
31. R. Voellmy Transcriptional regulation of the metazoan stress protein response Prog. Nucleic Acid Res. Mol. Biol. 78 2004 143 185 (Pubitemid 39752479)
32. K. Weis Regulating access to the genome: nucleocytoplasmic transport throughout the cell cycle Cell 112 2003 441 451 (Pubitemid 36263078)
33. W.J. Welch, and J.R. Feramisco Nuclear and nucleolar localization of the 72,000-dalton heat shock protein in heat-shocked mammalian cells J. Biol. Chem. 259 1984 4501 4513 (Pubitemid 14126903)
34. S.M. Wilbanks, C. DeLuca-Flaherty, and D.B. McKay Structural basis of the 70-kilodalton heat shock cognate protein ATP hydrolytic activity. I. Kinetic analyses of active site mutants J. Biol. Chem. 269 1994 12893 12898