The E2 domains of APP and APLP1 share a conserved mode of dimerization

Biochemistry

Volumn 50, Issue 24, 2011, Pages 5453-5464

  Lee, Sangwon ^a   Xue, Yi ^a   Hu, Jian ^a   Wang, Yongcheng ^a,c   Liu, Xuying ^a   Demeler, Borries ^b   Ha, Ya ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b University of Texas Health Science Center at San Antonio   (United States)

^c MONSANTO COMPANY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALZHEIMER'S DISEASE; AMYLOID PRECURSOR PROTEINS; HEPARIN BINDING; MEMBRANE PROTEINS; MUTATIONAL ANALYSIS; OLIGOMERIC STRUCTURE; PHOSPHATE IONS; PROTEIN DIMERIZATION; PROTEIN RESIDUES; PROTEIN SURFACE; SECRETASES; SPACE GROUPS;

BIOLOGICAL MEMBRANES; GLYCOPROTEINS; MAMMALS; OLIGOMERS; POLYSACCHARIDES; PROTEINS;

DIMERIZATION;

AMYLOID PRECURSOR PROTEIN; ARGININE; DIMER; HEPARIN; HISTIDINE; MEMBRANE PROTEIN; OLIGOMER; PHOSPHATE; PROTEIN APLP1; SECRETASE; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ARTICLE; CRYSTAL STRUCTURE; DIMERIZATION; MUTATION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PROCESSING; PROTEIN STRUCTURE;

AMINO ACID SUBSTITUTION; AMYLOID BETA-PROTEIN PRECURSOR; BINDING SITES; CONSERVED SEQUENCE; CRYSTALLOGRAPHY, X-RAY; DIMERIZATION; HEPARIN; HUMANS; MODELS, MOLECULAR; PHOSPHATES; PROTEIN BINDING; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; STATIC ELECTRICITY;

MAMMALIA;

EID: 79959284264     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi101846x     Document Type: Article

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