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Volumn 23, Issue 20, 2004, Pages 4106-4115

Cortical dysplasia resembling human type 2 lissencephaly in mice lacking all three APP family members

Author keywords

amyloid precursor protein; Alzheimer's disease; APLP; Lissencephaly; Triple knockout

Indexed keywords

AMYLOID PRECURSOR LIKE PROTEIN 1; AMYLOID PRECURSOR LIKE PROTEIN 2; AMYLOID PRECURSOR PROTEIN; UNCLASSIFIED DRUG;

EID: 8144230876     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.emboj.7600390     Document Type: Article
Times cited : (288)

References (51)
  • 1
    • 0016441382 scopus 로고
    • Some morphometric methods for the central nervous system
    • Aherne W (1975) Some morphometric methods for the central nervous system. J Neurol Sci 24: 221-241
    • (1975) J Neurol Sci , vol.24 , pp. 221-241
    • Aherne, W.1
  • 2
    • 0030030005 scopus 로고    scopus 로고
    • Regulation of amyloid protein precursor (APP) binding to collagen and mapping of the binding sites on APP and collagen type I
    • Beher D, Hesse L, Masters CL, Multhaup G (1996) Regulation of amyloid protein precursor (APP) binding to collagen and mapping of the binding sites on APP and collagen type I. J Biol Chem 271: 1613-1620
    • (1996) J Biol Chem , vol.271 , pp. 1613-1620
    • Beher, D.1    Hesse, L.2    Masters, C.L.3    Multhaup, G.4
  • 3
    • 0031149411 scopus 로고    scopus 로고
    • Widespread neuronal ectopia associated with secondary defects in cerebrocortical chondroitin sulfate proteoglycans and basal lamina in MARCKS-deficient mice
    • Blackshear PJ, Silver J, Nairn AC, Sulik KK, Squier MV, Stumpo DJ, Tuttle JS (1997) Widespread neuronal ectopia associated with secondary defects in cerebrocortical chondroitin sulfate proteoglycans and basal lamina in MARCKS-deficient mice. Exp Neurol 145: 46-61
    • (1997) Exp Neurol , vol.145 , pp. 46-61
    • Blackshear, P.J.1    Silver, J.2    Nairn, A.C.3    Sulik, K.K.4    Squier, M.V.5    Stumpo, D.J.6    Tuttle, J.S.7
  • 4
    • 0035816661 scopus 로고    scopus 로고
    • A transcriptively active complex of APP with Fe65 and histone acetyltransferase Tip60
    • Cao X, Südhof TC (2001) A transcriptively active complex of APP with Fe65 and histone acetyltransferase Tip60. Science 293: 115-120
    • (2001) Science , vol.293 , pp. 115-120
    • Cao, X.1    Südhof, T.C.2
  • 5
    • 2642582435 scopus 로고    scopus 로고
    • Dissection of amyloid b-precursor protein-dependent transcriptional activation
    • Cao X, Südhof TC (2004) Dissection of amyloid b-precursor protein-dependent transcriptional activation. J Biol Chem 279: 2460-24611
    • (2004) J Biol Chem , vol.279 , pp. 2460-24611
    • Cao, X.1    Südhof, T.C.2
  • 6
    • 0031026779 scopus 로고    scopus 로고
    • Identification of heparin-binding domains in the amyloid precursor protein of Alzheimer's disease by deletion mutagenesis and peptide mapping
    • Clarris HJ, Cappai R, Heffernan D, Beyreuther K, Masters CL, Small DH (1997) Identification of heparin-binding domains in the amyloid precursor protein of Alzheimer's disease by deletion mutagenesis and peptide mapping. J Neurochem 68: 1164-1172
    • (1997) J Neurochem , vol.68 , pp. 1164-1172
    • Clarris, H.J.1    Cappai, R.2    Heffernan, D.3    Beyreuther, K.4    Masters, C.L.5    Small, D.H.6
  • 7
    • 0035001534 scopus 로고    scopus 로고
    • Neuronal migration defects in the Dreher (Lmx1a) mutant mouse: Role of disorders of the glial limiting membrane
    • Costa C, Harding B, Copp AJ (2001) Neuronal migration defects in the Dreher (Lmx1a) mutant mouse: role of disorders of the glial limiting membrane. Cereb Cortex 11: 498-505
    • (2001) Cereb Cortex , vol.11 , pp. 498-505
    • Costa, C.1    Harding, B.2    Copp, A.J.3
  • 8
    • 0034049944 scopus 로고    scopus 로고
    • Proteolytic processing and cell biological functions of the amyloid precursor protein
    • De Strooper B, Annaert W (2000) Proteolytic processing and cell biological functions of the amyloid precursor protein. J Cell Sci 113: 1857-1870
    • (2000) J Cell Sci , vol.113 , pp. 1857-1870
    • De Strooper, B.1    Annaert, W.2
  • 9
    • 2442592973 scopus 로고    scopus 로고
    • The proteolytic processing of the amyloid precursor protein gene family members APLP-1 and APLP-2 involves a-, b-, g-, and e-like cleavages
    • Eggert S, Paligas K, Soba P, Evin G, Masters CL, Weidemann A, Beyreuther K (2004) The proteolytic processing of the amyloid precursor protein gene family members APLP-1 and APLP-2 involves a-, b-, g-, and e-like cleavages. J Biol Chem 279: 18146-18156
    • (2004) J Biol Chem , vol.279 , pp. 18146-18156
    • Eggert, S.1    Paligas, K.2    Soba, P.3    Evin, G.4    Masters, C.L.5    Weidemann, A.6    Beyreuther, K.7
  • 10
    • 0032572754 scopus 로고    scopus 로고
    • Essential role of alpha 6 integrins in cortical and retinal lamination
    • Georges-Labouesse E, Mark M, Messaddeq N, Gansmüller A (1998) Essential role of alpha 6 integrins in cortical and retinal lamination. Curr Biol 8: 983-986
    • (1998) Curr Biol , vol.8 , pp. 983-986
    • Georges-Labouesse, E.1    Mark, M.2    Messaddeq, N.3    Gansmüller, A.4
  • 11
    • 0034255316 scopus 로고    scopus 로고
    • Neuronal migration disorders: From genetic diseases to developmental mechanisms
    • Gleeson JG, Walsh CA (2000) Neuronal migration disorders: from genetic diseases to developmental mechanisms. Trends Neurosci 23: 352-359
    • (2000) Trends Neurosci , vol.23 , pp. 352-359
    • Gleeson, J.G.1    Walsh, C.A.2
  • 12
    • 0000684636 scopus 로고
    • Silver impregnation of reticulin in paraffin sections
    • Gomorri G (1937) Silver impregnation of reticulin in paraffin sections. Am J Pathol 13: 993-1002
    • (1937) Am J Pathol , vol.13 , pp. 993-1002
    • Gomorri, G.1
  • 14
    • 0030340041 scopus 로고    scopus 로고
    • Functions of brain chondroitin sulfate proteoglycans during developments: Interactions with adhesion molecules
    • Grumet M, Friedlander DR, Sakurai T (1996) Functions of brain chondroitin sulfate proteoglycans during developments: interactions with adhesion molecules. Perspect Dev Neurobiol 3: 319-330
    • (1996) Perspect Dev Neurobiol , vol.3 , pp. 319-330
    • Grumet, M.1    Friedlander, D.R.2    Sakurai, T.3
  • 16
    • 0035929554 scopus 로고    scopus 로고
    • Distinct intramembrane cleavage of the beta-amyloid precursor protein family resembling gamma-secretase-like cleavage of Notch
    • Gu Y, Misonou H, Sato T, Dohmae N, Takio K, Ihara Y (2001) Distinct intramembrane cleavage of the beta-amyloid precursor protein family resembling gamma-secretase-like cleavage of Notch. J Biol Chem 276: 35235-35238
    • (2001) J Biol Chem , vol.276 , pp. 35235-35238
    • Gu, Y.1    Misonou, H.2    Sato, T.3    Dohmae, N.4    Takio, K.5    Ihara, Y.6
  • 17
    • 0033565962 scopus 로고    scopus 로고
    • Presenilin-1 deficiency leads to loss of Cajal-Retzius neurons and cortical dysplasia similar to human type 2 lissencephaly
    • Hartmann D, De Strooper B, Saftig P (1999) Presenilin-1 deficiency leads to loss of Cajal-Retzius neurons and cortical dysplasia similar to human type 2 lissencephaly. Curr Biol 9: 719-727
    • (1999) Curr Biol , vol.9 , pp. 719-727
    • Hartmann, D.1    De Strooper, B.2    Saftig, P.3
  • 19
    • 0033198295 scopus 로고    scopus 로고
    • Disabled-1 binds to the cytoplasmic domain of amyloid precursor-like protein 1
    • Homayouni R, Rice DS, Sheldon M, Curran T (1999) Disabled-1 binds to the cytoplasmic domain of amyloid precursor-like protein 1. J Neurosci 19: 7507-7515
    • (1999) J Neurosci , vol.19 , pp. 7507-7515
    • Homayouni, R.1    Rice, D.S.2    Sheldon, M.3    Curran, T.4
  • 20
    • 0035818998 scopus 로고    scopus 로고
    • Kinesin-mediated axonal transport of a membrane compartment containing β-secretase and presenilin-1 requires APP
    • Kamal A, Almenar-Queralt A, LeBlanc JF, Roberts EA, Goldstein LSB (2001) Kinesin-mediated axonal transport of a membrane compartment containing β-secretase and presenilin-1 requires APP. Nature 414: 643-648
    • (2001) Nature , vol.414 , pp. 643-648
    • Kamal, A.1    Almenar-Queralt, A.2    LeBlanc, J.F.3    Roberts, E.A.4    Goldstein, L.S.B.5
  • 22
    • 0036843631 scopus 로고    scopus 로고
    • The beta-amyloid precursor protein (APP) and Alzheimer's disease: Does the tail wag the dog?
    • Koo EH (2002) The beta-amyloid precursor protein (APP) and Alzheimer's disease: does the tail wag the dog? Traffic 3: 763-770
    • (2002) Traffic , vol.3 , pp. 763-770
    • Koo, E.H.1
  • 23
    • 8144227644 scopus 로고    scopus 로고
    • Cleavage of APP and APLP's by BACE 1
    • Li Q, Südhof TC (2003) Cleavage of APP and APLP's by BACE 1. J Biol Chem 279: 10542-10550
    • (2003) J Biol Chem , vol.279 , pp. 10542-10550
    • Li, Q.1    Südhof, T.C.2
  • 24
    • 0029954239 scopus 로고    scopus 로고
    • Generation of mice with a 200-kb amyloid precursor protein gene deletion by Cre recombinase-mediated site-specific recombination in embryonic stem cells
    • Li ZW, Stark G, Götz J, Rülicke T, Gschwind M, Huber G, Müller U, Weissmann C (1996) Generation of mice with a 200-kb amyloid precursor protein gene deletion by Cre recombinase-mediated site-specific recombination in embryonic stem cells. Proc Natl Acad Sci USA 93: 6158-6162
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 6158-6162
    • Li, Z.W.1    Stark, G.2    Götz, J.3    Rülicke, T.4    Gschwind, M.5    Huber, G.6    Müller, U.7    Weissmann, C.8
  • 26
    • 0028914672 scopus 로고
    • Expression in mouse embryos and in adult mouse brain of three members of the amyloid precursor protein family, of the alpha-2-macroglobulin receptor/low density lipoprotein receptor-related protein and of its ligands apolipoprotein E, lipoprotein lipase, alpha-2-macroglobulin and the 40,000 molecular weight receptor-associated protein
    • Lorent K, Overbergh L, Moechars D, De Strooper B, Van Leuven F, Van den Berghe H (1995) Expression in mouse embryos and in adult mouse brain of three members of the amyloid precursor protein family, of the alpha-2-macroglobulin receptor/low density lipoprotein receptor-related protein and of its ligands apolipoprotein E, lipoprotein lipase, alpha-2-macroglobulin and the 40,000 molecular weight receptor-associated protein. Neuroscience 65: 1009-1025
    • (1995) Neuroscience , vol.65 , pp. 1009-1025
    • Lorent, K.1    Overbergh, L.2    Moechars, D.3    De Strooper, B.4    Van Leuven, F.5    Van Den Berghe, H.6
  • 27
    • 0033551143 scopus 로고    scopus 로고
    • Genetic background changes the pattern of forebrain commissure defects in transgenic mice underexpressing the beta-amyloid-precursor protein
    • Magara F, Müller U, Li ZW, Lipp HP, Weissmann C, Stagljar M, Wolfer DP (1999) Genetic background changes the pattern of forebrain commissure defects in transgenic mice underexpressing the beta-amyloid-precursor protein. Proc Natl Acad Sci USA 96: 4656-4661
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 4656-4661
    • Magara, F.1    Müller, U.2    Li, Z.W.3    Lipp, H.P.4    Weissmann, C.5    Stagljar, M.6    Wolfer, D.P.7
  • 28
    • 0037075201 scopus 로고    scopus 로고
    • Rescue of ataxia and preplate splitting by ectopic expression of Reelin in reeler mice
    • Magdaleno S, Keshvara L, Curran T (2002) Rescue of ataxia and preplate splitting by ectopic expression of Reelin in reeler mice. Neuron 33: 573-586
    • (2002) Neuron , vol.33 , pp. 573-586
    • Magdaleno, S.1    Keshvara, L.2    Curran, T.3
  • 32
    • 0031453752 scopus 로고    scopus 로고
    • The beta-amyloid precursor protein of Alzheimer's disease enhances neuron viability and modulates neuronal polarity
    • Perez RG, Zheng H, Van der Ploeg LH, Koo EH (1997) The beta-amyloid precursor protein of Alzheimer's disease enhances neuron viability and modulates neuronal polarity. J Neurosci 17: 9407-9414
    • (1997) J Neurosci , vol.17 , pp. 9407-9414
    • Perez, R.G.1    Zheng, H.2    Van Der Ploeg, L.H.3    Koo, E.H.4
  • 33
    • 0034932938 scopus 로고    scopus 로고
    • Role of the reelin signaling pathway in central nervous system development
    • Rice DS, Curran T (2001) Role of the reelin signaling pathway in central nervous system development. Annu Rev Neurosci 24: 1005-1039
    • (2001) Annu Rev Neurosci , vol.24 , pp. 1005-1039
    • Rice, D.S.1    Curran, T.2
  • 34
    • 0035954426 scopus 로고    scopus 로고
    • The Alzheimer amyloid precursor protein (APP) and FE65, an APP-binding protein, regulate cell movement
    • Sabo SL, Ikin AF, Buxbaum JD, Greengard P (2001) The Alzheimer amyloid precursor protein (APP) and FE65, an APP-binding protein, regulate cell movement. J Cell Biol 153: 1403-1414
    • (2001) J Cell Biol , vol.153 , pp. 1403-1414
    • Sabo, S.L.1    Ikin, A.F.2    Buxbaum, J.D.3    Greengard, P.4
  • 36
    • 0037114010 scopus 로고    scopus 로고
    • Processing of beta-amyloid precursor-like protein-1 and -2 by gamma-secretase regulates transcription
    • Scheinfeld MH, Ghersi E, Laky K, Fowlkes BJ, D'Adamio L (2002) Processing of beta-amyloid precursor-like protein-1 and -2 by gamma-secretase regulates transcription. J Biol Chem 277: 44195-44201
    • (2002) J Biol Chem , vol.277 , pp. 44195-44201
    • Scheinfeld, M.H.1    Ghersi, E.2    Laky, K.3    Fowlkes, B.J.4    D'Adamio, L.5
  • 37
    • 0028059841 scopus 로고
    • Expression of a ubiquitous, cross-reactive homologue of the mouse beta-amyloid precursor protein (APP)
    • Slunt HH, Thinakaran G, Von KC, Lo AC, Tanzi RE, Sisodia SS (1994) Expression of a ubiquitous, cross-reactive homologue of the mouse beta-amyloid precursor protein (APP). J Biol Chem 269: 2637-2644
    • (1994) J Biol Chem , vol.269 , pp. 2637-2644
    • Slunt, H.H.1    Thinakaran, G.2    Von, K.C.3    Lo, A.C.4    Tanzi, R.E.5    Sisodia, S.S.6
  • 39
    • 0030574061 scopus 로고    scopus 로고
    • Alzheimer's disease amyloid precursor protein on the surface of cortical neurons in primary culture co-localizes with adhesion patch components
    • Storey E, Beyreuther K, Masters CL (1996) Alzheimer's disease amyloid precursor protein on the surface of cortical neurons in primary culture co-localizes with adhesion patch components. Brain Res 735: 217-231
    • (1996) Brain Res , vol.735 , pp. 217-231
    • Storey, E.1    Beyreuther, K.2    Masters, C.L.3
  • 40
    • 0028883213 scopus 로고
    • MARCKS deficiency in mice leads to abnormal brain development and perinatal death
    • Stumpo DJ, Bock CB, Tuttle JS, Blackshear PJ (1995) MARCKS deficiency in mice leads to abnormal brain development and perinatal death. Proc Natl Acad Sci USA 92: 944-948
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 944-948
    • Stumpo, D.J.1    Bock, C.B.2    Tuttle, J.S.3    Blackshear, P.J.4
  • 41
    • 0007356347 scopus 로고
    • Tissue distribution and developmental expression of the amyloid precursor protein homolog, APLP1
    • Thinakaran G, Slunt HH, Spitzer L, Lee MK, Sisodia SS (1995) Tissue distribution and developmental expression of the amyloid precursor protein homolog, APLP1. Soc Neurosci Abstr 21: 205
    • (1995) Soc Neurosci Abstr , vol.21 , pp. 205
    • Thinakaran, G.1    Slunt, H.H.2    Spitzer, L.3    Lee, M.K.4    Sisodia, S.S.5
  • 43
    • 0032167904 scopus 로고    scopus 로고
    • Neurobehavioral development, adult openfield exploration and swimming navigation learning in mice with a modified beta-amyloid precursor protein gene
    • Tremml P, Lipp HP, Müller U, Ricceri L, Wolfer DP (1998) Neurobehavioral development, adult openfield exploration and swimming navigation learning in mice with a modified beta-amyloid precursor protein gene. Behav Brain Res 95: 65-76
    • (1998) Behav Brain Res , vol.95 , pp. 65-76
    • Tremml, P.1    Lipp, H.P.2    Müller, U.3    Ricceri, L.4    Wolfer, D.P.5
  • 44
    • 0032509346 scopus 로고    scopus 로고
    • Interaction of cytosolic adaptor proteins with neuronal apolipoprotein E receptors and the amyloid precursor protien
    • Trommsdorff M, Borg J-P, Margolis B, Herz J (1998) Interaction of cytosolic adaptor proteins with neuronal apolipoprotein E receptors and the amyloid precursor protien. J Biol Chem 273: 33556-33560
    • (1998) J Biol Chem , vol.273 , pp. 33556-33560
    • Trommsdorff, M.1    Borg, J.-P.2    Margolis, B.3    Herz, J.4
  • 47
    • 0038322593 scopus 로고    scopus 로고
    • Gamma-Secretase cleavage and binding to FE65 regulate the nuclear translocation of the intracellular C-terminal domain (ICD) of the APP family of proteins
    • Walsh DM, Fadeeva JV, LaVoie MJ, Paliga K, Eggert S, Kimberly WT, Wasco W, Selkoe DJ (2003) gamma-Secretase cleavage and binding to FE65 regulate the nuclear translocation of the intracellular C-terminal domain (ICD) of the APP family of proteins. Biochemistry 42: 6664-6673
    • (2003) Biochemistry , vol.42 , pp. 6664-6673
    • Walsh, D.M.1    Fadeeva, J.V.2    LaVoie, M.J.3    Paliga, K.4    Eggert, S.5    Kimberly, W.T.6    Wasco, W.7    Selkoe, D.J.8
  • 49
    • 0032529710 scopus 로고    scopus 로고
    • Survival of cultured neurons from amyloid precursor protein knock-out mice against Alzheimer's amyloid-beta toxicity and oxidative stress
    • White AR, Zheng H, Galatis D, Maher F, Hesse L, Multhaup G, Beyreuther K, Masters CL, Cappai R (1998) Survival of cultured neurons from amyloid precursor protein knock-out mice against Alzheimer's amyloid-beta toxicity and oxidative stress. J Neurosci 18: 6207-6217
    • (1998) J Neurosci , vol.18 , pp. 6207-6217
    • White, A.R.1    Zheng, H.2    Galatis, D.3    Maher, F.4    Hesse, L.5    Multhaup, G.6    Beyreuther, K.7    Masters, C.L.8    Cappai, R.9
  • 50
    • 0031020284 scopus 로고    scopus 로고
    • Cell surface amyloid beta-protein precursor colocalizes with beta 1 integrins at substrate contact sites in neural cells
    • Yamazaki T, Koo EH, Selkoe DJ (1997) Cell surface amyloid beta-protein precursor colocalizes with beta 1 integrins at substrate contact sites in neural cells. J Neurosci 17: 1004-1010
    • (1997) J Neurosci , vol.17 , pp. 1004-1010
    • Yamazaki, T.1    Koo, E.H.2    Selkoe, D.J.3


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