Bivalent and co-operative binding of complement Factor H to heparan sulfate and heparin

Biochemical Journal

Volumn 444, Issue 3, 2012, Pages 417-428

  Khan, Sanaullah ^a   Nan, Ruodan ^a   Gor, Jayesh ^a   Mulloy, Barbara ^b   Perkins, Stephen J ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b NATIONAL INSTITUTE FOR BIOLOGICAL STANDARDS AND CONTROL   (United Kingdom)

Author keywords

Analytical ultracentrifugation; Factor H; Heparan sulfate; Surface plasmon resonance; X ray scattering

Indexed keywords

COMPLEMENT FACTOR H; HEPARAN SULFATE; HEPARIN; MONOSACCHARIDE;

ARTICLE; BINDING AFFINITY; BINDING SITE; COMPLEX FORMATION; CONTROLLED STUDY; DISSOCIATION CONSTANT; MOLECULAR MECHANICS; PARTICLE SIZE; PRIORITY JOURNAL; PROTEIN STRUCTURE; RADIATION SCATTERING; SURFACE PLASMON RESONANCE; ULTRACENTRIFUGATION;

BINDING SITES; COMPLEMENT FACTOR H; HEPARIN; HEPARITIN SULFATE; HUMANS; MODELS, CHEMICAL; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; SCATTERING, SMALL ANGLE;

EID: 84862183665     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20120183     Document Type: Article

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