Structural and Energetic Characteristics of the Heparin-binding Site in Antithrombotic Protein C

Journal of Biological Chemistry

Volumn 276, Issue 26, 2001, Pages 24122-24128

  Friedrich, Ute ^a   Blom, Arma M ^a   Dahlbäck, Björn ^a   Villoutreix, Bruno O ^b  

^a LUND UNIVERSITY   (Sweden)

^b INSERM   (France)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; BLOOD; CATALYSIS; PROTEINS;

ELECTROPOSITIVE CHARACTERS;

BIOCHEMISTRY;

ANTITHROMBIN; CHYMOTRYPSINOGEN; EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; HEPARAN SULFATE; HEPARIN; PROTEIN C; RECOMBINANT PROTEIN; THROMBIN; PLASMINOGEN ACTIVATOR INHIBITOR 3; SODIUM CHLORIDE;

ADENOVIRUS; AFFINITY CHROMATOGRAPHY; ARTICLE; BINDING SITE; BLOOD CLOTTING; HUMAN; HUMAN CELL; IMMUNOBLOTTING; KIDNEY CELL; MEMBRANE BINDING; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN PURIFICATION; SURFACE PLASMON RESONANCE; THROMBOSIS; VIRUS CELL TRANSFORMATION; AMINO ACID SEQUENCE; CELL LINE; CHEMICAL STRUCTURE; CHEMISTRY; DRUG ANTAGONISM; ELECTRICITY; KINETICS; METABOLISM; MOLECULAR GENETICS; PROTEIN BINDING; SEQUENCE HOMOLOGY; SITE DIRECTED MUTAGENESIS;

ADENOVIRIDAE;

AMINO ACID SEQUENCE; BINDING SITES; CELL LINE, TRANSFORMED; ELECTROSTATICS; HEPARIN; HUMANS; KINETICS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PROTEIN BINDING; PROTEIN C; PROTEIN C INHIBITOR; SEQUENCE HOMOLOGY, AMINO ACID; SODIUM CHLORIDE;

EID: 0035968239     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M011567200     Document Type: Article

References (37)

1. Davie, E. W., Fujikawa, K., and Kisiel, W. (1991) Biochemistry 30, 10363-10370
2. Esmon, C. T., Ding, W., Yasuhiro, K., Gu, J. M., Ferrell, G., Regan, L. M., Stearns-Kurosawa, D. J., Kurosawa, S., Mather, T., Laszik, Z., and Esmon, N. L. (1997) Thromb. Haemostasis 78, 70-74
3. Dahlbäck, B. (2000) Lancet 355, 1627-1632
4. Furie, B., and Furie, B. C. (1988) Cell 53, 505-518
5. Kalafatis, M., Rand, M. D., and Mann, K. G. (1994) J. Biol. Chem. 269, 31869-31880
6. Rosing, J., and Tans, G. (1997) Thromb. Haemostasis 78, 427-433
7. Heeb, M. J., and Griffin, J. H. (1988) J. Biol. Chem. 263, 11613-11616
8. Hermans, J. M., and Stone, S. R. (1993) Biochem. J. 295, 239-245
9. Aznar, J., Espana, F., Estelles, A., and Royo, M. (1996) Thromb. Haemostasis 76, 983-988
10. Neese, L. L., Wolfe, C. A., and Church, F. C. (1998) Arch. Biochem. Biophys. 355, 101-108
11. Olson, S. T., and Bjork, I. (1991) J. Biol. Chem. 266, 6353-6364
12. Olson, S. T., and Bjork, I. (1994) Semin. Thromb. Hemostasis 20, 373-409
13. Shen, L., Villoutreix, B. O., and Dahlbäck, B. (1999) Thromb. Haemostasis 82, 72-79
14. Shen, L., Dahlbäck, B., and Villoutreix, B. O. (2000) Biochemistry 39, 2853-2860
15. Cardin, A. D., and Weintraub, H. J. (1989) Arteriosclerosis 9, 21-32
16. Montserret, R., Aubert-Foucher, E., McLeish, M. J., Hill, J. M., Ficheux, D., Jaquinod, M., van der Rest, M., Deleage, G., and Penin, F. (1999) Biochemistry 38, 6479-6488
17. Sali, A., Matsumoto, R., McNeil, H. P., Karplus, M., and Stevens, R. L. (1993) J. Biol. Chem. 268, 9023-9034
18. Matsumoto, R., Sali, A., Ghildyal, N., Karplus, M., and Stevens, R. L. (1995) J. Biol. Chem. 270, 19524-19531
19. Murakami, M., Matsumoto, R., Urade, Y., Austen, K. F., and Arm, J. P. (1995) J. Biol. Chem. 270, 3239-3246
20. Ghildyal, N., Friend, D. S., Stevens, R. L., Austen, K. F., Huang, C., Penrose, J. F., Sali, A., and Gurish, M. F. (1996) J. Exp. Med. 184, 1061-1073
21. Wacey, A. I., Pemberton, S., Cooper, D. N., Kakkar, V. V., and Tuddenham, E. G. (1993) Br. J. Haematol. 84, 290-300
22. Fisher, C. L., Greengard, J. S., and Griffin, J. H. (1994) Protein Sci. 3, 588-599
23. Mather, T., Oganessyan, V., Hof, P., Huber, R., Foundling, S., Esmon, C., and Bode, W. (1996) EMBO J. 15, 6822-6831
24. Zhou, H., Casas-Finet, J. R., Heath Coats, R., Kaufman, J. D., Stahl, S. J., Wingfield, P. T., Rubin, J. S., Bottaro, D. P., and Byrd, R. A. (1999) Biochemistry 38, 14793-14802
25. Dahlbäck, B., and Hildebrand, B. (1994) Proc. Natl. Acad. Sci. U. S. A. 91, 1396-1400
26. Friedrich, U., Potzsch, B., Preissner, K. T., Muller-Berghaus, G., and Ehrlich, H. (1994) Thromb. Haemostasis 72, 567-572
27. Pfleiderer, G. (1970) Methods Enzymol. 19, 514-521
28. Cleland, W. (1979) Methods Enzymol. 63, 103-138
29. Record, M. T., Jr., Anderson, C. F., and Lohman, T. M. (1978) Q. Rev. Biophys. 11, 103-178
30. Manning, G. S. (1978) Q. Rev. Biophys. 11, 179-246
31. Hari, S. P., McAllister, H., Chuang, W. L., Christ, M. D., and Rabenstein, D. L. (2000) Biochemistry 39, 3763-3773
32. Thompson, L. D., Pantoliano, M. W., and Springer, B. A. (1994) Biochemistry 33, 3831-3840
33. Faham, S., Hileman, R. E., Fromm, J. R., Linhardt, R. J., and Rees, D. C. (1996) Science 271, 1116-1120
34. Faller, B., Mely, Y., Gerard, D., and Bieth, J. G. (1992) Biochemistry 31, 8285-8290
35. Smoluchowski, M. V. (1918) Z. Phys. Chem. 92, 129-168
36. Sheehan, J. P., and Sadler, J. E. (1994) Proc. Natl. Acad. Sci. U. S. A. 91, 5518-5522
37. Ersdal-Badju, E., Lu, A., Zuo, Y., Picard, V., and Bock, S. C. (1997) J. Biol. Chem. 272, 19393-19400