Crystal structure of the E2 domain of amyloid precursor protein-like protein 1 in complex with sucrose octasulfate

Journal of Biological Chemistry

Volumn 286, Issue 34, 2011, Pages 29748-29757

  Xue, Yi ^a   Lee, Sangwon ^a   Wang, Yongcheng ^b   Ha, Ya ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b MONSANTO COMPANY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALZHEIMER DISEASE; AMYLOID PRECURSOR PROTEINS; EXTRACELLULAR MATRICES; HEK293 CELLS; HEPARIN BINDING; HEPARIN-BINDING SITE; INTERFACIAL SITES; LOWER RESOLUTION; MUTATIONAL ANALYSIS; SECRETASES; SUCROSE OCTASULFATE;

DIMERS; ENZYME INHIBITION; GENES; GLYCOPROTEINS; POLYSACCHARIDES; PROTEINS; SIGNAL TRANSDUCTION; SUGAR (SUCROSE); SYSTEMS ENGINEERING;

CRYSTAL STRUCTURE;

AMYLOID PRECURSOR PROTEIN; AMYLOID PRECURSOR PROTEIN LIKE PROTEIN 1; ARGININE; HEPARIN; HISTIDINE; LYSINE; MEMBRANE PROTEIN; POLYSACCHARIDE; SECRETASE; SUCRALFATE; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; CELL STRAIN HEK293; CONTROLLED STUDY; CRYSTAL STRUCTURE; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; MUTATIONAL ANALYSIS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN INTERACTION; PROTEIN PROCESSING; PROTEIN STRUCTURE;

AMINO ACID SUBSTITUTION; AMYLOID BETA-PROTEIN PRECURSOR; AMYLOID PRECURSOR PROTEIN SECRETASES; CRYSTALLOGRAPHY, X-RAY; HEK293 CELLS; HUMANS; MUTATION, MISSENSE; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, TERTIARY;

EID: 80051937835     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.219659     Document Type: Article

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