Proteoglycan-specific molecular switch for RPTPσ clustering and neuronal extension

Science

Volumn 332, Issue 6028, 2011, Pages 484-488

  Coles, Charlotte H ^a   Shen, Yingjie ^b   Tenney, Alan P ^b,c   Siebold, Christian ^a   Sutton, Geoffrey C ^a   Lu, Weixian ^a   Gallagher, John T ^d   Jones, E Yvonne ^a   Flanagan, John G ^b   Aricescu, A Radu ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b HARVARD MEDICAL SCHOOL   (United States)

^c Och Spine at New York Presbyterian Hospitals   (United States)

^d UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CHONDROITIN SULFATE; HEPARAN SULFATE; PROTEOCHONDROITIN SULFATE; PROTEOHEPARAN SULFATE; RECEPTOR; RECEPTOR PROTEIN TYROSINE PHOSPHATASE SIGMA; UNCLASSIFIED DRUG;

ENZYME ACTIVITY; INHIBITION; NEUROLOGY; PROTEIN;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; BINDING SITE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CRYSTALLOGRAPHY; EXTRACELLULAR MATRIX; MOUSE; NONHUMAN; OLIGOMERIZATION; PLASTICITY; PRIORITY JOURNAL; PROTEIN DOMAIN; SENSORY NERVE CELL;

AMINO ACID SEQUENCE; ANIMALS; AXONS; BINDING SITES; CELL MEMBRANE; CELLS, CULTURED; CHONDROITIN SULFATE PROTEOGLYCANS; CHONDROITIN SULFATES; CRYSTALLOGRAPHY, X-RAY; EXTRACELLULAR MATRIX; GANGLIA, SPINAL; GLYPICANS; GROWTH CONES; HEPARAN SULFATE PROTEOGLYCANS; HEPARITIN SULFATE; HUMANS; MICE; MODELS, BIOLOGICAL; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; NEURITES; NEUROCAN; PROTEIN CONFORMATION; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, TERTIARY; RECEPTOR-LIKE PROTEIN TYROSINE PHOSPHATASES, CLASS 2; SENSORY RECEPTOR CELLS;

EID: 79955470793     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1200840     Document Type: Article

References (36)

1. K. G. Johnson, D. Van Vactor, Physiol. Rev. 83, 1 (2003).
2. Y. Duan, R. J. Giger, Sci. Signal. 3, pe6 (2010).
3. N. K. Tonks, Nat. Rev. Mol. Cell Biol. 7, 833 (2006).
4. F. Rashid-Doubell, I. McKinnell, A. R. Aricescu, G. Sajnani, A. W. Stoker, J. Neurosci. 22, 5024 (2002).
5. A. N. Fox, K. Zinn, Curr. Biol. 15, 1701 (2005).
6. A. W. Dunah et al., Nat. Neurosci. 8, 458 (2005).
7. K. G. Johnson et al., Neuron 49, 517 (2006).
8. J. Woo et al., Nat. Neurosci. 12, 428 (2009).
9. M. J. Wallace et al., Nat. Genet. 21, 334 (1999).
10. M. Elchebly et al., Nat. Genet. 21, 330 (1999).
11. J. McLean, J. Batt, L. C. Doering, D. Rotin, J. R. Bain, J. Neurosci. 22, 5481 (2002).
12. Y. Shen et al., Science 326, 592 (2009); 10.1126/ science.1178310.
13. E. J. Fry, M. J. Chagnon, R. López-Vales, M. L. Tremblay, S. David, Glia 58, 423 (2010).
14. P. S. Sapieha et al., Mol. Cell. Neurosci. 28, 625 (2005).
15. K. M. Thompson et al., Mol. Cell. Neurosci. 23, 681 (2003).
16. N. Uetani et al., EMBO J. 19, 2775 (2000).
17. N. Uetani, M. J. Chagnon, T. E. Kennedy, Y. Iwakura, M. L. Tremblay, J. Neurosci. 26, 5872 (2006).
18. A. R. Aricescu, I. W. McKinnell, W. Halfter, A. W. Stoker, Mol. Cell. Biol. 22, 1881 (2002).
19. C. E. Bandtlow, D. R. Zimmermann, Physiol. Rev. 80, 1267 (2000).
20. D. Van Vactor, D. P. Wall, K. G. Johnson, Curr. Opin. Neurobiol. 16, 40 (2006).
21. J. Silver, J. H. Miller, Nat. Rev. Neurosci. 5, 146 (2004).
22. D. B. Kantor et al., Neuron 44, 961 (2004).
23. Y. Matsumoto, F. Irie, M. Inatani, M. Tessier-Lavigne, Y. Yamaguchi, J. Neurosci. 27, 4342 (2007).
24. C. M. Galtrey, J. W. Fawcett, Brain Res. Brain Res. Rev. 54, 1 (2007).
25. L. C. Case, M. Tessier-Lavigne, Curr. Biol. 15, R749 (2005).
26. M. M. Ledig, F. Haj, J. L. Bixby, A. W. Stoker, B. K. Mueller, J. Cell Biol. 147, 375 (1999).
27. A. R. Aricescu, W. Lu, E. Y. Jones, Acta Crystallogr. D Biol. Crystallogr. 62, 1243 (2006).
28. Materials and methods are available as supporting material on Science Online.
29. Single-letter abbreviations for the amino acid residues are as follows: D, Asp; F, Phe; K, Lys; R, Arg; and V, Val.
30. B. Mulloy, M. J. Forster, C. Jones, D. B. Davies, Biochem. J. 293, 849 (1993).
31. T. Spivak-Kroizman et al., Cell 79, 1015 (1994).
32. N. J. Harmer et al., Biochem. J. 393, 741 (2006).
33. K. J. Murphy et al., J. Biol. Chem. 279, 27239 (2004).
34. J. T. Groves, J. Kuriyan, Nat. Struct. Mol. Biol. 17, 659 (2010).
35. D. Y. Wu, D. J. Goldberg, J. Cell Biol. 123, 653 (1993).
36. E. Robles, S. Woo, T. M. Gomez, J. Neurosci. 25, 7669 (2005).