Neuroprotective secreted amyloid precursor protein acts by disrupting amyloid precursor protein dimers

Journal of Biological Chemistry

Volumn 284, Issue 22, 2009, Pages 15016-15025

  Gralle, Matthias ^a   Botelho, Michelle Gralle ^b   Wouters, Fred S ^a,c  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

^b MAX PLANCK INSTITUTE FOR BIOPHYSICAL CHEMISTRY   (Germany)

^c MAX PLANCK INSTITUTE FOR EVOLUTIONARY ANTHROPOLOGY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ALZHEIMER DISEASE; AMYLOID PEPTIDES; AMYLOID PRECURSOR PROTEINS; BENEFICIAL EFFECTS; ECTODOMAIN; EXTRACELLULAR LIGANDS; FLUORESCENCE LIFETIME IMAGING MICROSCOPY; HEPARAN SULFATES; HOMODIMERIZATION; INTRACELLULAR MEMBRANES; NEUROBLASTOMA CELLS; NEURODEGENERATIVE; NEURONAL DYSFUNCTION; NEURONAL SURVIVAL; PLASMA MEMBRANES; QUANTUM DOT; RESONANCE ENERGY TRANSFER; SELECTIVE LABELING; SINGLE MOLECULE; SYNAPTIC PLASTICITY; TRANSMEMBRANE; WILD TYPES;

AMINES; BINDING ENERGY; CELL DEATH; CELL MEMBRANES; DIMERIZATION; DIMERS; ENERGY TRANSFER; ENZYME ACTIVITY; FLUORESCENCE; GLYCOPROTEINS; GROWTH KINETICS; PLASMAS; SEMICONDUCTOR QUANTUM DOTS; SIGNALING;

PUMPING PLANTS;

ALPHA SECRETASE; AMYLOID PRECURSOR PROTEIN; DIMER; MUTANT PROTEIN; QUANTUM DOT; ACYL CARRIER PROTEIN; GREEN FLUORESCENT PROTEIN; HEPARIN; NEUROPROTECTIVE AGENT;

ANIMAL CELL; ARTICLE; CELL DEATH; CELL MEMBRANE; CELL SURVIVAL; CONTROLLED STUDY; DIMERIZATION; LIGAND BINDING; NEUROBLASTOMA CELL; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN MODIFICATION; PROTEIN SECRETION; RAT; SIGNAL TRANSDUCTION; ANIMAL; BIOLOGICAL MODEL; CHEMISTRY; DRUG EFFECT; METABOLISM; NEUROBLASTOMA; PATHOLOGY; PROTEIN MULTIMERIZATION; SECRETION; TUMOR CELL LINE;

ACYL CARRIER PROTEIN; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; CELL LINE, TUMOR; CELL MEMBRANE; CELL SURVIVAL; GREEN FLUORESCENT PROTEINS; HEPARIN; MODELS, BIOLOGICAL; NEUROBLASTOMA; NEUROPROTECTIVE AGENTS; PROTEIN MULTIMERIZATION; QUANTUM DOTS;

EID: 67649366042     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M808755200     Document Type: Article

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