Cooperative dimerization of fibroblast growth factor 1 (FGF1) upon a single heparin saccharide may drive the formation of 2:2:1 FGF1·FGFR2c· heparin ternary complexes

Journal of Biological Chemistry

Volumn 280, Issue 51, 2005, Pages 42274-42282

  Robinson, Christopher J ^a   Harmer, Nicholas J ^b   Goodger, Sarah J ^a   Blundell, Tom L ^b   Gallagher, John T ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; CHROMATOGRAPHIC ANALYSIS; GLYCOLS; OLIGOMERS; SACCHARIFICATION; SULFUR COMPOUNDS; TERNARY SYSTEMS;

CELL SURFACE; FIBROPLAST GROWTH FACTOR (FGF); HEPARAN SULFATE; SIGNALING COMPLEX;

DIMERIZATION;

FIBROBLAST GROWTH FACTOR 1; FIBROBLAST GROWTH FACTOR RECEPTOR 2; FIBROBLAST GROWTH FACTOR RECEPTOR 2C; GLYCOSAMINOGLYCAN; HEPARAN SULFATE; HEPARIN; OLIGOSACCHARIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CELL SURFACE; COMPLEX FORMATION; DIMERIZATION; GEL PERMEATION CHROMATOGRAPHY; HUMAN; MITOGENESIS; MOLECULAR INTERACTION; NONHUMAN; PRIORITY JOURNAL; RECEPTOR BINDING; SIGNAL TRANSDUCTION;

CHROMATOGRAPHY, GEL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DIMERIZATION; FIBROBLAST GROWTH FACTOR 1; HEPARIN; HUMANS; RECEPTOR, FIBROBLAST GROWTH FACTOR, TYPE 2;

ANIMALIA;

EID: 29644438840     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M505720200     Document Type: Article

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