Plasticity in interactions of Fibroblast Growth Factor 1 (FGF1) N terminus with FGF receptors underlies promiscuity of FGF1

Journal of Biological Chemistry

Volumn 287, Issue 5, 2012, Pages 3067-3078

  Beenken, Andrew ^a   Eliseenkova, Anna V ^a   Ibrahimi, Omar A ^a,b,c   Olsen, Shaun K ^a,d   Mohammadi, Moosa ^a  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF CONNECTICUT HEALTH CENTER   (United States)

^c MASSACHUSETTS GENERAL HOSPITAL   (United States)

^d MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALTERNATIVE SPLICING; CROSS-REACTIVITY; FGF RECEPTORS; FIBROBLAST GROWTH FACTOR; FIBROBLAST GROWTH FACTOR RECEPTORS; FIBROBLAST GROWTH FACTOR-1; ISOFORMS; LIGAND BINDING; MOLECULAR BASIS; N-TERMINALS; RECEPTOR BINDING; SELECTIVITY FILTER; STRUCTURAL DATA; TRIPLE MUTANTS;

CELL CULTURE; FIBROBLASTS; GROWTH KINETICS; LIGANDS; PEPTIDES; PLASTICITY; TISSUE;

CRYSTAL STRUCTURE;

ASPARAGINE; ASPARAGINE 22; COMPLEMENTARY DNA; FIBROBLAST GROWTH FACTOR 1; FIBROBLAST GROWTH FACTOR 10; FIBROBLAST GROWTH FACTOR 2; FIBROBLAST GROWTH FACTOR 8; FIBROBLAST GROWTH FACTOR RECEPTOR 1; FIBROBLAST GROWTH FACTOR RECEPTOR 2; FIBROBLAST GROWTH FACTOR RECEPTOR 3; GLYCINE; GLYCINE 19; HISTIDINE; HISTIDINE 25; ISOPROTEIN; KILLER CELL IMMUNOGLOBULIN LIKE RECEPTOR; PHENYLALANINE; PHENYLALANINE 26; RNA; TYROSINE; TYROSINE 23; TYROSINE KINASE RECEPTOR; UNCLASSIFIED DRUG;

ALTERNATIVE RNA SPLICING; AMINO TERMINAL SEQUENCE; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; CROSS REACTION; CRYSTAL STRUCTURE; CRYSTALLIZATION; GENETIC VARIABILITY; GLUCOSE HOMEOSTASIS; LIGAND BINDING; PLASTICITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PURIFICATION; RECEPTOR BINDING; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY; SURFACE PLASMON RESONANCE; TISSUE SPECIFICITY;

AMINO ACID SUBSTITUTION; CRYSTALLOGRAPHY, X-RAY; FIBROBLAST GROWTH FACTOR 1; HUMANS; MUTATION, MISSENSE; PROTEIN BINDING; PROTEIN ISOFORMS; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, FIBROBLAST GROWTH FACTOR; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84856301540     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.275891     Document Type: Article

References (70)

1. Beenken, A., and Mohammadi, M. (2009) Nat. Rev. Drug Discov. 8, 235-253
2. Kuro-o, M. (2008) Trends Endocrinol. Metab. 19, 239-245
3. Ornitz, D. M. (2005) Cytokine Growth Factor Rev. 16, 205-213
4. Itoh, N., and Ornitz, D. M. (2004) Trends Genet. 20, 563-569
5. Popovici, C., Roubin, R., Coulier, F., and Birnbaum, D. (2005) BioEssays 27, 849-857
6. Goetz, R., Dover, K., Laezza, F., Shtraizent, N., Huang, X., Tchetchik, D., Eliseenkova, A. V., Xu, C. F., Neubert, T. A., Ornitz, D. M., Goldfarb, M., and Mohammadi, M. (2009) J. Biol. Chem. 284, 17883-17896
7. Goldfarb, M. (2005) Cytokine Growth Factor Rev. 16, 215-220
8. Olsen, S. K., Garbi, M., Zampieri, N., Eliseenkova, A. V., Ornitz, D. M., Goldfarb, M., and Mohammadi, M. (2003) J. Biol. Chem. 278, 34226-34236
9. Beenken, A., and Mohammadi, M. (2012) in Versatile Biological Functions of FGF1 (Kuro-o, M., ed) Landes Bioscience, Austin, TX
10. Fu, L., John, L. M., Adams, S. H., Yu, X. X., Tomlinson, E., Renz, M., Williams, P. M., Soriano, R., Corpuz, R., Moffat, B., Vandlen, R., Simmons, L., Foster, J., Stephan, J. P., Tsai, S. P., and Stewart, T. A. (2004) Endocrinology 145, 2594-2603
11. Holt, J. A., Luo, G., Billin, A. N., Bisi, J., McNeill, Y. Y., Kozarsky, K. F., Donahee, M., Wang, D. Y., Mansfield, T. A., Kliewer, S. A., Goodwin, B., and Jones, S. A. (2003) Genes Dev. 17, 1581-1591
12. Lundåsen, T., Gälman, C., Angelin, B., and Rudling, M. (2006) J. Intern. Med. 260, 530-536
13. Tomlinson, E., Fu, L., John, L., Hultgren, B., Huang, X., Renz, M., Stephan, J. P., Tsai, S. P., Powell-Braxton, L., French, D., and Stewart, T. A. (2002) Endocrinology 143, 1741-1747
14. Coskun, T., Bina, H. A., Schneider, M. A., Dunbar, J. D., Hu, C. C., Chen, Y., Moller, D. E., and Kharitonenkov, A. (2008) Endocrinology 149, 6018-6027
15. Kharitonenkov, A., Shiyanova, T. L., Koester, A., Ford, A. M., Micanovic, R., Galbreath, E. J., Sandusky, G. E., Hammond, L. J., Moyers, J. S., Owens, R. A., Gromada, J., Brozinick, J. T., Hawkins, E. D., Wroblewski, V. J., Li, D. S., Mehrbod, F., Jaskunas, S. R., and Shanafelt, A. B. (2005) J. Clin. Invest. 115, 1627-1635
16. Kharitonenkov, A., Wroblewski, V. J., Koester, A., Chen, Y. F., Clutinger, C. K., Tigno, X. T., Hansen, B. C., Shanafelt, A. B., and Etgen, G. J. (2007) Endocrinology 148, 774-781
17. Xu, J., Lloyd, D. J., Hale, C., Stanislaus, S., Chen, M., Sivits, G., Vonderfecht, S., Hecht, R., Li, Y. S., Lindberg, R. A., Chen, J. L., Jung, D. Y., Zhang, Z., Ko, H. J., Kim, J. K., and Véniant, M. M. (2009) Diabetes 58, 250-259
18. Inoue, Y., Segawa, H., Kaneko, I., Yamanaka, S., Kusano, K., Kawakami, E., Furutani, J., Ito, M., Kuwahata, M., Saito, H., Fukushima, N., Kato, S., Kanayama, H. O., and Miyamoto, K. (2005) Biochem. J. 390, 325-331
19. Saito, H., Kusano, K., Kinosaki, M., Ito, H., Hirata, M., Segawa, H., Miyamoto, K., and Fukushima, N. (2003) J. Biol. Chem. 278, 2206-2211
20. Segawa, H., Kawakami, E., Kaneko, I., Kuwahata, M., Ito, M., Kusano, K., Saito, H., Fukushima, N., and Miyamoto, K. (2003) Pflugers Arch. 446, 585-592
21. Ornitz, D. M., Yayon, A., Flanagan, J. G., Svahn, C. M., Levi, E., and Leder, P. (1992) Mol. Cell Biol. 12, 240-247
22. Rapraeger, A. C., Krufka, A., and Olwin, B. B. (1991) Science 252, 1705-1708
23. Yayon, A., Klagsbrun, M., Esko, J. D., Leder, P., and Ornitz, D. M. (1991) Cell 64, 841-848
24. Goetz, R., Beenken, A., Ibrahimi, O. A., Kalinina, J., Olsen, S. K., Eliseenkova, A. V., Xu, C., Neubert, T. A., Zhang, F., Linhardt, R. J., Yu, X., White, K. E., Inagaki, T., Kliewer, S. A., Yamamoto, M., Kurosu, H., Ogawa, Y., Kuro-o, M., Lanske, B., Razzaque, M. S., and Mohammadi, M. (2007) Mol. Cell Biol. 27, 3417-3428
25. Kurosu, H., Ogawa, Y., Miyoshi, M., Yamamoto, M., Nandi, A., Rosenblatt, K. P., Baum, M. G., Schiavi, S., Hu, M. C., Moe, O. W., and Kuro-o, M. (2006) J. Biol. Chem. 281, 6120-6123
26. Urakawa, I., Yamazaki, Y., Shimada, T., Iijima, K., Hasegawa, H., Okawa, K., Fujita, T., Fukumoto, S., and Yamashita, T. (2006) Nature 444, 770-774
27. Givol, D., and Yayon, A. (1992) FASEB J. 6, 3362-3369
28. Johnson, D. E., and Williams, L. T. (1993) Adv. Cancer Res. 60, 1-41
29. Lee, P. L., Johnson, D. E., Cousens, L. S., Fried, V. A., and Williams, L. T. (1989) Science 245, 57-60
30. Olsen, S. K., Li, J. Y., Bromleigh, C., Eliseenkova, A. V., Ibrahimi, O. A., Lao, Z., Zhang, F., Linhardt, R. J., Joyner, A. L., and Mohammadi, M. (2006) Genes Dev. 20, 185-198
31. Plotnikov, A. N., Hubbard, S. R., Schlessinger, J., and Mohammadi, M. (2000) Cell 101, 413-424
32. Plotnikov, A. N., Schlessinger, J., Hubbard, S. R., and Mohammadi, M. (1999) Cell 98, 641-650
33. Stauber, D. J., DiGabriele, A. D., and Hendrickson, W. A. (2000) Proc. Natl. Acad. Sci. U.S.A. 97, 49-54
34. Yeh, B. K., Igarashi, M., Eliseenkova, A. V., Plotnikov, A. N., Sher, I., Ron, D., Aaronson, S. A., and Mohammadi, M. (2003) Proc. Natl. Acad. Sci. U.S.A. 100, 2266-2271
35. Olsen, S. K., Ibrahimi, O. A., Raucci, A., Zhang, F., Eliseenkova, A. V., Yayon, A., Basilico, C., Linhardt, R. J., Schlessinger, J., and Mohammadi, M. (2004) Proc. Natl. Acad. Sci. U.S.A. 101, 935-940
36. Wang, F., Kan, M., Yan, G., Xu, J., and McKeehan, W. L. (1995) J. Biol. Chem. 270, 10231-10235
37. Mohammadi, M., Olsen, S. K., and Ibrahimi, O. A. (2005) Cytokine Growth Factor Rev. 16, 107-137
38. Schlessinger, J., Plotnikov, A. N., Ibrahimi, O. A., Eliseenkova, A. V., Yeh, B. K., Yayon, A., Linhardt, R. J., and Mohammadi, M. (2000) Mol. Cell 6, 743-750
39. Chen, H., Xu, C. F., Ma, J., Eliseenkova, A. V., Li, W., Pollock, P. M., Pitteloud, N., Miller, W. T., Neubert, T. A., and Mohammadi, M. (2008) Proc. Natl. Acad. Sci. U.S.A. 105, 19660-19665
40. Mohammadi, M., Dikic, I., Sorokin, A., Burgess, W. H., Jaye, M., and Schlessinger, J. (1996) Mol. Cell Biol. 16, 977-989
41. Kouhara, H., Hadari, Y. R., Spivak-Kroizman, T., Schilling, J., Bar-Sagi, D., Lax, I., and Schlessinger, J. (1997) Cell 89, 693-702
42. Huang, J., Mohammadi, M., Rodrigues, G. A., and Schlessinger, J. (1995) J. Biol. Chem. 270, 5065-5072
43. Mohammadi, M., Dionne, C. A., Li, W., Li, N., Spivak, T., Honegger, A. M., Jaye, M., and Schlessinger, J. (1992) Nature 358, 681-684
44. Carballada, R., Yasuo, H., and Lemaire, P. (2001) Development 128, 35-44
45. Hadari, Y. R., Gotoh, N., Kouhara, H., Lax, I., and Schlessinger, J. (2001) Proc. Natl. Acad. Sci. U.S.A. 98, 8578-8583
46. Ong, S. H., Hadari, Y. R., Gotoh, N., Guy, G. R., Schlessinger, J., and Lax, I. (2001) Proc. Natl. Acad. Sci. U.S.A. 98, 6074-6079
47. Seo, J. H., Suenaga, A., Hatakeyama, M., Taiji, M., and Imamoto, A. (2009) Mol. Cell Biol. 29, 3076-3087
48. Dailey, L., Ambrosetti, D., Mansukhani, A., and Basilico, C. (2005) Cytokine Growth Factor Rev. 16, 233-247
49. Eswarakumar, V. P., Lax, I., and Schlessinger, J. (2005) Cytokine Growth Factor Rev. 16, 139-149
50. Ornitz, D. M., Xu, J., Colvin, J. S., McEwen, D. G., MacArthur, C. A., Coulier, F., Gao, G., and Goldfarb, M. (1996) J. Biol. Chem. 271, 15292-15297
51. Zhang, X., Ibrahimi, O. A., Olsen, S. K., Umemori, H., Mohammadi, M., and Ornitz, D. M. (2006) J. Biol. Chem. 281, 15694-15700
52. Chellaiah, A. T., McEwen, D. G., Werner, S., Xu, J., and Ornitz, D. M. (1994) J. Biol. Chem. 269, 11620-11627
53. Johnson, D. E., Lu, J., Chen, H., Werner, S., and Williams, L. T. (1991) Mol. Cell Biol. 11, 4627-4634
54. Miki, T., Bottaro, D. P., Fleming, T. P., Smith, C. L., Burgess, W. H., Chan, A. M., and Aaronson, S. A. (1992) Proc. Natl. Acad. Sci. U.S.A. 89, 246-250
55. Yayon, A., Zimmer, Y., Shen, G. H., Avivi, A., Yarden, Y., and Givol, D. (1992) EMBO J. 11, 1885-1890
56. Chellaiah, A., Yuan, W., Chellaiah, M., and Ornitz, D. M. (1999) J. Biol. Chem. 274, 34785-34794
57. Ron, D., Reich, R., Chedid, M., Lengel, C., Cohen, O. E., Chan, A. M., Neufeld, G., Miki, T., and Tronick, S. R. (1993) J. Biol. Chem. 268, 5388-5394
58. Vainikka, S., Partanen, J., Bellosta, P., Coulier, F., Birnbaum, D., Basilico, C., Jaye, M., and Alitalo, K. (1992) EMBO J. 11, 4273-4280
59. MacArthur, C. A., Lawshé, A., Xu, J., Santos-Ocampo, S., Heikinheimo, M., Chellaiah, A. T., and Ornitz, D. M. (1995) Development 121, 3603-3613
60. Otwinowski, Z., and Minor, W. (1997) Methods Enzymol. 276, 307-326
61. Navaza, J. (1994) Acta Crystallogr. A 50, 157-163
62. Jones, T. A., Zou, J. Y., Cowan, S. W., and Kjeldgaard, M. (1991) Acta Crystallogr. A 47, 110-119
63. Brünger, A. T., Adams, P. D., Clore, G. M., DeLano, W. L., Gros, P., Grosse-Kunstleve, R. W., Jiang, J. S., Kuszewski, J., Nilges, M., Pannu, N. S., Read, R. J., Rice, L. M., Simonson, T., and Warren, G. L. (1998) Acta Crystallogr. D Biol. Crystallogr. 54, 905-921
64. Gartside, M. G., Chen, H., Ibrahimi, O. A., Byron, S. A., Curtis, A. V., Wellens, C. L., Bengston, A., Yudt, L. M., Eliseenkova, A. V., Ma, J., Curtin, J. A., Hyder, P., Harper, U. L., Riedesel, E., Mann, G. J., Trent, J. M., Bastian, B. C., Meltzer, P. S., Mohammadi, M., and Pollock, P. M. (2009) Mol. Cancer Res. 7, 41-54
65. Byron, S. A., Gartside, M. G., Wellens, C. L., Goodfellow, P. J., Birrer, M. J., Campbell, I. G., and Pollock, P. M. (2010) Gynecol. Oncol. 117, 125-129
66. Ibrahimi, O. A., Eliseenkova, A. V., Plotnikov, A. N., Yu, K., Ornitz, D. M., and Mohammadi, M. (2001) Proc. Natl. Acad. Sci. U.S.A. 98, 7182-7187
67. Ibrahimi, O. A., Zhang, F., Eliseenkova, A. V., Itoh, N., Linhardt, R. J., and Mohammadi, M. (2004) Hum. Mol. Genet. 13, 2313-2324
68. Ibrahimi, O. A., Yeh, B. K., Eliseenkova, A. V., Zhang, F., Olsen, S. K., Igarashi, M., Aaronson, S. A., Linhardt, R. J., and Mohammadi, M. (2005) Mol. Cell Biol. 25, 671-684
69. Luo, Y., Gabriel, J. L., Wang, F., Zhan, X., Maciag, T., Kan, M., and McKeehan, W. L. (1996) J. Biol. Chem. 271, 26876-26883
70. Wu, X., Ge, H., Lemon, B., Vonderfecht, S., Baribault, H., Weiszmann, J., Gupte, J., Gardner, J., Lindberg, R., Wang, Z., and Li, Y. (2010) Proc. Natl. Acad. Sci. U.S.A. 107, 14158-14163