메뉴 건너뛰기




Volumn , Issue , 2012, Pages 469-515

Molecular pathology of cancer metastasis: Suggestions for future therapy

Author keywords

[No Author keywords available]

Indexed keywords


EID: 84902185808     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1007/978-1-61779-615-9_18     Document Type: Chapter
Times cited : (7)

References (332)
  • 3
    • 33749086099 scopus 로고
    • Observations on the local diseases termed malignant
    • Travers B. Observations on the local diseases termed malignant. Med Chir Trans. 1829;15:195-262.
    • (1829) Med Chir Trans , vol.15 , pp. 195-262
    • Travers, B.1
  • 5
    • 0034443811 scopus 로고    scopus 로고
    • Metastasis of cancer: A conceptual history from antiquity to the 1990s
    • 193-383
    • Weiss L. Metastasis of cancer: a conceptual history from antiquity to the 1990s. Cancer Metastasis Rev. 2000;19(3-4):I-XI, 193-383.
    • (2000) Cancer Metastasis Rev , vol.19 , Issue.3-4 , pp. I-XI
    • Weiss, L.1
  • 6
    • 0024708518 scopus 로고
    • The distribution of secondary growths in cancer of the breast. 1889
    • Paget S. The distribution of secondary growths in cancer of the breast. 1889. Cancer Metastasis Rev. 1989;8 (2):98-101.
    • (1989) Cancer Metastasis Rev , vol.8 , Issue.2 , pp. 98-101
    • Paget, S.1
  • 7
    • 0024575589 scopus 로고
    • Cellular pathology. As based upon physiological and pathological histology. Lecture XVI-Atheromatous affection of arteries. 1858
    • Virchow R. Cellular pathology. As based upon physiological and pathological histology. Lecture XVI-Atheromatous affection of arteries. 1858. Nutr Rev. 1989;47 (1):23-5.
    • (1989) Nutr Rev , vol.47 , Issue.1 , pp. 23-25
    • Virchow, R.1
  • 9
    • 0026042387 scopus 로고
    • Detection of melanoma cells in peripheral blood by means of reverse transcriptase and polymerase chain reaction
    • Smith B, Selby P, Southgate J, Pittman K, Bradley C, Blair GE. Detection of melanoma cells in peripheral blood by means of reverse transcriptase and polymerase chain reaction. Lancet. 1991;338 (8777): 1227-9.
    • (1991) Lancet , vol.338 , Issue.8777 , pp. 1227-1229
    • Smith, B.1    Selby, P.2    Southgate, J.3    Pittman, K.4    Bradley, C.5    Blair, G.E.6
  • 10
    • 24644439190 scopus 로고    scopus 로고
    • Trends in the leading causes of death in the United States, 1970-2002
    • Jemal A, Ward E, Hao Y, Thun M. Trends in the leading causes of death in the United States, 1970-2002. JAMA. 2005;294 (10):1255-9.
    • (2005) JAMA , vol.294 , Issue.10 , pp. 1255-1259
    • Jemal, A.1    Ward, E.2    Hao, Y.3    Thun, M.4
  • 11
    • 0015612853 scopus 로고
    • An autopsy study of some routes of dissemination of cancer of the breast
    • Viadana E, Bross ID, Pickren JW. An autopsy study of some routes of dissemination of cancer of the breast. Br J Cancer. 1973;27 (4):336-40.
    • (1973) Br J Cancer , vol.27 , Issue.4 , pp. 336-340
    • Viadana, E.1    Bross, I.D.2    Pickren, J.W.3
  • 12
    • 0021721949 scopus 로고
    • Metastatic patterns of prostatic cancer. Correlation between sites and number of organs involved
    • Saitoh H, Hida M, Shimbo T, Nakamura K, Yamagata J, Satoh T. Metastatic patterns of prostatic cancer. Correlation between sites and number of organs involved. Cancer. 1984;54 (12):3078-84.
    • (1984) Cancer , vol.54 , Issue.12 , pp. 3078-3084
    • Saitoh, H.1    Hida, M.2    Shimbo, T.3    Nakamura, K.4    Yamagata, J.5    Satoh, T.6
  • 13
    • 68549126099 scopus 로고
    • The time of appearance of metastases after surgical removal of the primary tumor
    • Henneford J, Baserga R, Wartman WB. The time of appearance of metastases after surgical removal of the primary tumor. Br J Cancer. 1962;16:599-607.
    • (1962) Br J Cancer , vol.16 , pp. 599-607
    • Henneford, J.1    Baserga, R.2    Wartman, W.B.3
  • 15
    • 0029060132 scopus 로고
    • Pathologists request autopsy revival
    • 1891
    • Marwick C. Pathologists request autopsy revival. JAMA. 1995;273(24):1889, 1891.
    • (1995) JAMA , vol.273 , Issue.24 , pp. 1889
    • Marwick, C.1
  • 17
    • 0024411613 scopus 로고
    • More lung cancer but better survival. Implications of secular trends in "necropsy surprise" rates
    • Chan CK, Wells CK, McFarlane MJ, Feinstein AR. More lung cancer but better survival. Implications of secular trends in "necropsy surprise" rates. Chest. 1989;96 (2):291-6.
    • (1989) Chest , vol.96 , Issue.2 , pp. 291-296
    • Chan, C.K.1    Wells, C.K.2    McFarlane, M.J.3    Feinstein, A.R.4
  • 18
  • 20
    • 0023301838 scopus 로고
    • The biology of cancer metastasis and implications for therapy
    • Fidler IJ, Balch CM. The biology of cancer metastasis and implications for therapy. Curr Probl Surg. 1987;24 (3): 129-209.
    • (1987) Curr Probl Surg , vol.24 , Issue.3 , pp. 129-209
    • Fidler, I.J.1    Balch, C.M.2
  • 21
    • 0017183752 scopus 로고
    • Patterns of recurrence following surgery alone for adenocarcinoma of the colon and rectum
    • Cass AW, Million RR, Pfaff WW. Patterns of recurrence following surgery alone for adenocarcinoma of the colon and rectum. Cancer. 1976;37 (6): 2861-5.
    • (1976) Cancer , vol.37 , Issue.6 , pp. 2861-2865
    • Cass, A.W.1    Million, R.R.2    Pfaff, W.W.3
  • 22
    • 84965274717 scopus 로고
    • Pelvic recurrence after excision of rectum for carcinoma
    • Morson BC, Vaughan EG, Bussey HJ. Pelvic recurrence after excision of rectum for carcinoma. Br Med J. 1963;2 (5348):13-8.
    • (1963) Br Med J , vol.2 , Issue.5348 , pp. 13-18
    • Morson, B.C.1    Vaughan, E.G.2    Bussey, H.J.3
  • 23
    • 0018761436 scopus 로고
    • The clinical correlation of an autopsy study of recurrent colorectal cancer
    • Welch JP, Donaldson GA. The clinical correlation of an autopsy study of recurrent colorectal cancer. Ann Surg. 1979;189 (4):496-502.
    • (1979) Ann Surg , vol.189 , Issue.4 , pp. 496-502
    • Welch, J.P.1    Donaldson, G.A.2
  • 24
    • 0017684153 scopus 로고
    • The metastatic spread of bronchogenic carcinoma in relation to the interval between resection and death
    • Weiss W, Gillick JS. The metastatic spread of bronchogenic carcinoma in relation to the interval between resection and death. Chest. 1977;71 (6): 725-9.
    • (1977) Chest , vol.71 , Issue.6 , pp. 725-729
    • Weiss, W.1    Gillick, J.S.2
  • 25
    • 23944466427 scopus 로고    scopus 로고
    • A pooled analysis of bone marrow micrometastasis in breast cancer
    • Braun S, Vogl FD, Naume B, et al. A pooled analysis of bone marrow micrometastasis in breast cancer. N Engl J Med. 2005;353 (8):793-802.
    • (2005) N Engl J Med , vol.353 , Issue.8 , pp. 793-802
    • Braun, S.1    Vogl, F.D.2    Naume, B.3
  • 26
    • 0033970143 scopus 로고    scopus 로고
    • Detection and analysis of cancer cells in blood and bone marrow using a rare event imaging system
    • Kraeft SK, Sutherland R, Gravelin L, et al. Detection and analysis of cancer cells in blood and bone marrow using a rare event imaging system. Clin Cancer Res. 2000;6 (2):434-42.
    • (2000) Clin Cancer Res , vol.6 , Issue.2 , pp. 434-442
    • Kraeft, S.K.1    Sutherland, R.2    Gravelin, L.3
  • 27
    • 0034947347 scopus 로고    scopus 로고
    • Disseminated cytokeratin positive tumor cells in the bone marrow of patients with prostate cancer: Detection and prognostic value
    • Weckermann D, Muller P, Wawroschek F, Harzmann R, Riethmuller G, Schlimok G. Disseminated cytokeratin positive tumor cells in the bone marrow of patients with prostate cancer: detection and prognostic value. J Urol. 2001;166 (2):699-703.
    • (2001) J Urol , vol.166 , Issue.2 , pp. 699-703
    • Weckermann, D.1    Muller, P.2    Wawroschek, F.3    Harzmann, R.4    Riethmuller, G.5    Schlimok, G.6
  • 28
    • 0033996457 scopus 로고    scopus 로고
    • Cytokeratin-positive cells in the bone marrow and survival of patients with stage I, II, or III breast cancer
    • Braun S, Pantel K, Muller P, et al. Cytokeratin-positive cells in the bone marrow and survival of patients with stage I, II, or III breast cancer. N Engl J Med. 2000;342 (8):525-33.
    • (2000) N Engl J Med , vol.342 , Issue.8 , pp. 525-533
    • Braun, S.1    Pantel, K.2    Muller, P.3
  • 29
    • 0019784176 scopus 로고
    • Causes of treatment failure and death in carcinoma of the lung
    • Cox JD, Yesner RA. Causes of treatment failure and death in carcinoma of the lung. Yale J Biol Med. 1981;54 (3):201-7.
    • (1981) Yale J Biol Med , vol.54 , Issue.3 , pp. 201-207
    • Cox, J.D.1    Yesner, R.A.2
  • 30
    • 84966196190 scopus 로고
    • Bronchial carcinoma: A statistical study of 741 necropsies with special reference to the distribution of blood-borne metastases
    • Galluzzi S, Payne PM. Bronchial carcinoma: a statistical study of 741 necropsies with special reference to the distribution of blood-borne metastases. Br J Cancer. 1955;9 (4):511-27.
    • (1955) Br J Cancer , vol.9 , Issue.4 , pp. 511-527
    • Galluzzi, S.1    Payne, P.M.2
  • 31
    • 0000725452 scopus 로고
    • Significance of metastasis in primary carcinoma of the lungs: Report of 2 cases with unusual site of metastasis
    • Ochsner A, DeBakey M. Significance of metastasis in primary carcinoma of the lungs: report of 2 cases with unusual site of metastasis. J Thorac Surg. 1942;11:357-87.
    • (1942) J Thorac Surg , vol.11 , pp. 357-387
    • Ochsner, A.1    DeBakey, M.2
  • 33
    • 0008002653 scopus 로고
    • Metastases in carcinoma; analysis of 1000 autopsied cases
    • Abrams HL, Spiro R, Goldstein N. Metastases in carcinoma; analysis of 1000 autopsied cases. Cancer. 1950;3 (1):74-85.
    • (1950) Cancer , vol.3 , Issue.1 , pp. 74-85
    • Abrams, H.L.1    Spiro, R.2    Goldstein, N.3
  • 34
    • 0015536339 scopus 로고
    • An autopsy study of metastatic sites of breast cancer
    • Viadana E, Cotter R, Pickren JW, Bross ID. An autopsy study of metastatic sites of breast cancer. Cancer Res. 1973;33 (1):179-81.
    • (1973) Cancer Res , vol.33 , Issue.1 , pp. 179-181
    • Viadana, E.1    Cotter, R.2    Pickren, J.W.3    Bross, I.D.4
  • 35
    • 0018888910 scopus 로고
    • Causes of death and metastatic patterns in patients with mammary cancer. Ten-year autopsy study
    • Cho SY, Choi HY. Causes of death and metastatic patterns in patients with mammary cancer. Ten-year autopsy study. Am J Clin Pathol. 1980;73 (2):232-4.
    • (1980) Am J Clin Pathol , vol.73 , Issue.2 , pp. 232-234
    • Cho, S.Y.1    Choi, H.Y.2
  • 36
    • 0015146630 scopus 로고
    • Survival of patients at Pennsylvania Hospital with hepatic metastases from carcinoma of the colon and rectum
    • Abrams MS, Lerner HJ. Survival of patients at Pennsylvania Hospital with hepatic metastases from carcinoma of the colon and rectum. Dis Colon Rectum. 1971;14 (6):431-4.
    • (1971) Dis Colon Rectum , vol.14 , Issue.6 , pp. 431-434
    • Abrams, M.S.1    Lerner, H.J.2
  • 37
    • 0001046991 scopus 로고
    • Sites of metastases from carcinoma of the anus, rectum and sigmoid colon
    • Bacon H, Gilbert P. Sites of metastases from carcinoma of the anus, rectum and sigmoid colon. JAMA. 1938;111:219-21.
    • (1938) JAMA , vol.111 , pp. 219-221
    • Bacon, H.1    Gilbert, P.2
  • 38
    • 0009731866 scopus 로고
    • Carcinoma of the large intestine; review of 416 autopsy records
    • Buirge R. Carcinoma of the large intestine; review of 416 autopsy records. Arch Surg. 1941;42:801-18.
    • (1941) Arch Surg , vol.42 , pp. 801-818
    • Buirge, R.1
  • 39
    • 0017712374 scopus 로고
    • The significance of metastases to the adrenal gland from carcinoma of the stomach and esophagus
    • Cedermark BJ, Blumenson LE, Pickren JW, Elias EG. The significance of metastases to the adrenal gland from carcinoma of the stomach and esophagus. Surg Gynecol Obstet. 1977;145 (1):41-8.
    • (1977) Surg Gynecol Obstet , vol.145 , Issue.1 , pp. 41-48
    • Cedermark, B.J.1    Blumenson, L.E.2    Pickren, J.W.3    Elias, E.G.4
  • 40
    • 10844235652 scopus 로고    scopus 로고
    • Androgen-independent prostate cancer is a heterogeneous group of diseases: Lessons from a rapid autopsy program
    • Shah RB, Mehra R, Chinnaiyan AM, et al. Androgen-independent prostate cancer is a heterogeneous group of diseases: lessons from a rapid autopsy program. Cancer Res. 2004;64 (24):9209-16.
    • (2004) Cancer Res , vol.64 , Issue.24 , pp. 9209-9216
    • Shah, R.B.1    Mehra, R.2    Chinnaiyan, A.M.3
  • 41
    • 0034085989 scopus 로고    scopus 로고
    • Metastatic patterns of prostate cancer: An autopsy study of 1,589 patients
    • Bubendorf L, Schopfer A, Wagner U, et al. Metastatic patterns of prostate cancer: an autopsy study of 1,589 patients. Hum Pathol. 2000;31 (5):578-83.
    • (2000) Hum Pathol , vol.31 , Issue.5 , pp. 578-583
    • Bubendorf, L.1    Schopfer, A.2    Wagner, U.3
  • 42
    • 0021994016 scopus 로고
    • Patterns of metastasis and natural courses of breast carcinoma
    • Lee YT. Patterns of metastasis and natural courses of breast carcinoma. Cancer Metastasis Rev. 1985;4 (2):153-72.
    • (1985) Cancer Metastasis Rev , vol.4 , Issue.2 , pp. 153-172
    • Lee, Y.T.1
  • 43
    • 0016612985 scopus 로고
    • Patterns of metastases in adenocarcinomas of man. An autopsy study of 4,728 cases
    • Viadana E, Au KL. Patterns of metastases in adenocarcinomas of man. An autopsy study of 4,728 cases. J Med. 1975;6 (1):1-14.
    • (1975) J Med , vol.6 , Issue.1 , pp. 1-14
    • Viadana, E.1    Au, K.L.2
  • 44
    • 0018150954 scopus 로고
    • The metastatic spread of cancers of the digestive system in man
    • Viadana E, Bross ID, Pickren JW. The metastatic spread of cancers of the digestive system in man. Oncology. 1978;35 (3):114-26.
    • (1978) Oncology , vol.35 , Issue.3 , pp. 114-126
    • Viadana, E.1    Bross, I.D.2    Pickren, J.W.3
  • 45
    • 0022969737 scopus 로고
    • Haematogenous metastatic patterns in colonic carcinoma: An analysis of 1541 necropsies
    • Weiss L, Grundmann E, Torhorst J, et al. Haematogenous metastatic patterns in colonic carcinoma: an analysis of 1541 necropsies. J Pathol. 1986;150 (3): 195-203.
    • (1986) J Pathol , vol.150 , Issue.3 , pp. 195-203
    • Weiss, L.1    Grundmann, E.2    Torhorst, J.3
  • 46
    • 0026554008 scopus 로고
    • Comments on hematogenous metastatic patterns in humans as revealed by autopsy
    • Weiss L. Comments on hematogenous metastatic patterns in humans as revealed by autopsy. Clin Exp Metastasis. 1992;10 (3):191-9.
    • (1992) Clin Exp Metastasis , vol.10 , Issue.3 , pp. 191-199
    • Weiss, L.1
  • 47
    • 0020573039 scopus 로고
    • Liver-to-lung traffic of cancer cells
    • Weiss L, Ward PM, Holmes JC. Liver-to-lung traffic of cancer cells. Int J Cancer. 1983;32 (1):79-83.
    • (1983) Int J Cancer , vol.32 , Issue.1 , pp. 79-83
    • Weiss, L.1    Ward, P.M.2    Holmes, J.C.3
  • 49
    • 44949201212 scopus 로고    scopus 로고
    • Dying with cancer, living well with advanced cancer
    • Higginson IJ, Costantini M. Dying with cancer, living well with advanced cancer. Eur J Cancer. 2008;44 (10): 1414-24.
    • (2008) Eur J Cancer , vol.44 , Issue.10 , pp. 1414-1424
    • Higginson, I.J.1    Costantini, M.2
  • 50
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • Hanahan D, Weinberg RA. The hallmarks of cancer. Cell. 2000;100 (1):57-70.
    • (2000) Cell , vol.100 , Issue.1 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 51
    • 0016167138 scopus 로고
    • Proceedings: Causes of death in cancer patients
    • Inagaki J, Rodriguez V, Bodey GP. Proceedings: causes of death in cancer patients. Cancer. 1974;33 (2):568-73.
    • (1974) Cancer , vol.33 , Issue.2 , pp. 568-573
    • Inagaki, J.1    Rodriguez, V.2    Bodey, G.P.3
  • 53
    • 0035002084 scopus 로고    scopus 로고
    • Physiological changes and clinical correlations of dyspnea in cancer outpatients
    • Dudgeon DJ, Lertzman M, Askew GR. Physiological changes and clinical correlations of dyspnea in cancer outpatients. J Pain Symptom Manage. 2001;21 (5):373-9.
    • (2001) J Pain Symptom Manage , vol.21 , Issue.5 , pp. 373-379
    • Dudgeon, D.J.1    Lertzman, M.2    Askew, G.R.3
  • 54
  • 55
    • 13444256137 scopus 로고    scopus 로고
    • Malignancies, prothrombotic mutations, and the risk of venous thrombosis
    • Blom JW, Doggen CJ, Osanto S, Rosendaal FR. Malignancies, prothrombotic mutations, and the risk of venous thrombosis. JAMA. 2005;293 (6):715-22.
    • (2005) JAMA , vol.293 , Issue.6 , pp. 715-722
    • Blom, J.W.1    Doggen, C.J.2    Osanto, S.3    Rosendaal, F.R.4
  • 56
    • 0036830917 scopus 로고    scopus 로고
    • Cachexia in cancer patients
    • Tisdale MJ. Cachexia in cancer patients. Nat Rev Cancer. 2002;2 (11):862-71.
    • (2002) Nat Rev Cancer , vol.2 , Issue.11 , pp. 862-871
    • Tisdale, M.J.1
  • 60
    • 33646696885 scopus 로고    scopus 로고
    • Anti-TNF antibody therapy in rheumatoid arthritis and the risk of serious infections and malignancies: Systematic review and meta-analysis of rare harmful effects in randomized controlled trials
    • Bongartz T, Sutton AJ, Sweeting MJ, Buchan I, Matteson EL, Montori V. Anti-TNF antibody therapy in rheumatoid arthritis and the risk of serious infections and malignancies: systematic review and meta-analysis of rare harmful effects in randomized controlled trials. JAMA. 2006;295 (19):2275-85.
    • (2006) JAMA , vol.295 , Issue.19 , pp. 2275-2285
    • Bongartz, T.1    Sutton, A.J.2    Sweeting, M.J.3    Buchan, I.4    Matteson, E.L.5    Montori, V.6
  • 61
    • 0141783943 scopus 로고    scopus 로고
    • Multidetector CT of peritoneal carcinomatosis from ovarian cancer
    • Pannu HK, Bristow RE, Montz FJ, Fishman EK. Multidetector CT of peritoneal carcinomatosis from ovarian cancer. Radiographics. 2003;23 (3):687-701.
    • (2003) Radiographics , vol.23 , Issue.3 , pp. 687-701
    • Pannu, H.K.1    Bristow, R.E.2    Montz, F.J.3    Fishman, E.K.4
  • 62
    • 0345496231 scopus 로고
    • Experimental studies on the spread of cancer in the lymphatic system. III. Tumor emboli in thoracic duct; the pathogenesis of Virchow's node
    • Zeidman I. Experimental studies on the spread of cancer in the lymphatic system. III. Tumor emboli in thoracic duct; the pathogenesis of Virchow's node. Cancer Res. 1955;15 (11):719-21.
    • (1955) Cancer Res , vol.15 , Issue.11 , pp. 719-721
    • Zeidman, I.1
  • 63
    • 78651131569 scopus 로고
    • Experimental studies on the spread of cancer in the lymphatic system. IV. Retrograde spread
    • Zeidman I. Experimental studies on the spread of cancer in the lymphatic system. IV. Retrograde spread. Cancer Res. 1959;19:1114-7.
    • (1959) Cancer Res , vol.19 , pp. 1114-1117
    • Zeidman, I.1
  • 64
    • 0020028031 scopus 로고
    • Radical prostatectomy for stage B2 prostatic cancer
    • Middleton RG, Smith Jr.JA. Radical prostatectomy for stage B2 prostatic cancer. J Urol. 1982;127 (4): 702-3.
    • (1982) J Urol , vol.127 , Issue.4 , pp. 702-703
    • Middleton, R.G.1    Smith, J.A.2
  • 65
    • 0033400105 scopus 로고    scopus 로고
    • Isolated tumor cells in bone marrow predict reduced survival in node-negative non-small cell lung cancer
    • Passlick B, Kubuschok B, Izbicki JR, Thetter O, Pantel K. Isolated tumor cells in bone marrow predict reduced survival in node-negative non-small cell lung cancer. Ann Thorac Surg. 1999;68 (6):2053-8.
    • (1999) Ann Thorac Surg , vol.68 , Issue.6 , pp. 2053-2058
    • Passlick, B.1    Kubuschok, B.2    Izbicki, J.R.3    Thetter, O.4    Pantel, K.5
  • 66
    • 0033532955 scopus 로고    scopus 로고
    • Detection and clinical importance of micrometastatic disease
    • Pantel K, Cote RJ, Fodstad O. Detection and clinical importance of micrometastatic disease. J Natl Cancer Inst. 1999;91 (13):1113-24.
    • (1999) J Natl Cancer Inst , vol.91 , Issue.13 , pp. 1113-1124
    • Pantel, K.1    Cote, R.J.2    Fodstad, O.3
  • 67
    • 0025148102 scopus 로고
    • Breast conservation is the treatment of choice in small breast cancer: Long-term results of a randomized trial
    • Veronesi U, Banfi A, Salvadori B, et al. Breast conservation is the treatment of choice in small breast cancer: long-term results of a randomized trial. Eur J Cancer. 1990;26 (6):668-70.
    • (1990) Eur J Cancer , vol.26 , Issue.6 , pp. 668-670
    • Veronesi, U.1    Banfi, A.2    Salvadori, B.3
  • 68
    • 58149191223 scopus 로고    scopus 로고
    • Efficacy of systematic pelvic lymphadenectomy in endometrial cancer (MRC ASTEC trial): A randomised study
    • Kitchener H, Swart AM, Qian Q, Amos C, Parmar MK. Efficacy of systematic pelvic lymphadenectomy in endometrial cancer (MRC ASTEC trial): a randomised study. Lancet. 2009;373 (9658):125-36.
    • (2009) Lancet , vol.373 , Issue.9658 , pp. 125-136
    • Kitchener, H.1    Swart, A.M.2    Qian, Q.3    Amos, C.4    Parmar, M.K.5
  • 69
    • 0001777467 scopus 로고
    • The results of radical operations for the cure of carcinoma of the breast
    • Halsted WS. I. The results of radical operations for the cure of carcinoma of the breast. Ann Surg. 1907;46 (1):1-19.
    • (1907) Ann Surg , vol.46 , Issue.1 , pp. 1-19
    • Halsted, W.S.I.1
  • 70
    • 0019198579 scopus 로고
    • Laboratory and clinical research in breast cancer-a personal adventure: The David A. Karnofsky memorial lecture
    • Fisher B. Laboratory and clinical research in breast cancer-a personal adventure: the David A. Karnofsky memorial lecture. Cancer Res. 1980;40 (11):3863-74.
    • (1980) Cancer Res , vol.40 , Issue.11 , pp. 3863-3874
    • Fisher, B.1
  • 71
    • 79951846893 scopus 로고    scopus 로고
    • Significance and mechanism of lymph node metastasis in cancer progression
    • Kawada K, Taketo MM. Significance and mechanism of lymph node metastasis in cancer progression. Cancer Res. 2011;71 (4):1214-8.
    • (2011) Cancer Res , vol.71 , Issue.4 , pp. 1214-1218
    • Kawada, K.1    Taketo, M.M.2
  • 72
    • 0345209746 scopus 로고
    • Vascular invasion in carcinoma of the colon and rectum
    • Burns FJ, Pfaff Jr.J. Vascular invasion in carcinoma of the colon and rectum. Am J Surg. 1956;92 (5): 704-9.
    • (1956) Am J Surg , vol.92 , Issue.5 , pp. 704-709
    • Burns, F.J.1    Pfaff, J.2
  • 73
    • 0017728030 scopus 로고
    • Significance of the vertebral venous (Batson's) plexus in metastatic spread in colorectal carcinoma
    • Vider M, Maruyama Y, Narvaez R. Significance of the vertebral venous (Batson's) plexus in metastatic spread in colorectal carcinoma. Cancer. 1977;40 (1): 67-71.
    • (1977) Cancer , vol.40 , Issue.1 , pp. 67-71
    • Vider, M.1    Maruyama, Y.2    Narvaez, R.3
  • 74
    • 0018864610 scopus 로고
    • The pathogenesis of cancer metastasis
    • Poste G, Fidler IJ. The pathogenesis of cancer metastasis. Nature. 1980;283 (5743):139-46.
    • (1980) Nature , vol.283 , Issue.5743 , pp. 139-146
    • Poste, G.1    Fidler, I.J.2
  • 75
    • 0022480660 scopus 로고
    • Evidence that the process of murine melanoma metastasis is sequential and selective and contains stochastic elements
    • Price JE, Aukerman SL, Fidler IJ. Evidence that the process of murine melanoma metastasis is sequential and selective and contains stochastic elements. Cancer Res. 1986;46 (10):5172-8.
    • (1986) Cancer Res , vol.46 , Issue.10 , pp. 5172-5178
    • Price, J.E.1    Aukerman, S.L.2    Fidler, I.J.3
  • 76
    • 0032510494 scopus 로고    scopus 로고
    • A causal role for E-cadherin in the transition from adenoma to carcinoma
    • Perl AK, Wilgenbus P, Dahl U, Semb H, Christofori G. A causal role for E-cadherin in the transition from adenoma to carcinoma. Nature. 1998;392 (6672): 190-3.
    • (1998) Nature , vol.392 , Issue.6672 , pp. 190-193
    • Perl, A.K.1    Wilgenbus, P.2    Dahl, U.3    Semb, H.4    Christofori, G.5
  • 77
    • 24344467835 scopus 로고    scopus 로고
    • Transendothelial migration of melanoma cells involves N-cadherin-mediated adhesion and activation of the beta-catenin signaling pathway
    • Qi J, Chen N, Wang J, Siu CH. Transendothelial migration of melanoma cells involves N-cadherin-mediated adhesion and activation of the beta-catenin signaling pathway. Mol Biol Cell. 2005;16 (9):4386-97.
    • (2005) Mol Biol Cell , vol.16 , Issue.9 , pp. 4386-4397
    • Qi, J.1    Chen, N.2    Wang, J.3    Siu, C.H.4
  • 78
    • 0030915026 scopus 로고    scopus 로고
    • N-cadherin promotes adhesion between invasive breast cancer cells and the stroma
    • Hazan RB, Kang L, Whooley BP, Borgen PI. N-cadherin promotes adhesion between invasive breast cancer cells and the stroma. Cell Adhes Commun. 1997;4 (6):399-411.
    • (1997) Cell Adhes Commun , vol.4 , Issue.6 , pp. 399-411
    • Hazan, R.B.1    Kang, L.2    Whooley, B.P.3    Borgen, P.I.4
  • 79
    • 0034235575 scopus 로고    scopus 로고
    • Cadherin switching in human prostate cancer progression
    • Tomita K, van Bokhoven A, van Leenders GJ, et al. Cadherin switching in human prostate cancer progression. Cancer Res. 2000;60 (13):3650-4.
    • (2000) Cancer Res , vol.60 , Issue.13 , pp. 3650-3654
    • Tomita, K.1    van Bokhoven, A.2    van Leenders, G.J.3
  • 80
    • 52449124146 scopus 로고    scopus 로고
    • Cadherin-11 promotes the metastasis of prostate cancer cells to bone
    • Chu K, Cheng CJ, Ye X, et al. Cadherin-11 promotes the metastasis of prostate cancer cells to bone. Mol Cancer Res. 2008;6 (8):1259-67.
    • (2008) Mol Cancer Res , vol.6 , Issue.8 , pp. 1259-1267
    • Chu, K.1    Cheng, C.J.2    Ye, X.3
  • 81
    • 63549149565 scopus 로고    scopus 로고
    • Clinical and pharmacological phase I evaluation of Exherin (ADH-1), a selective anti-N-cadherin peptide in patients with N-cadherin-expressing solid tumours
    • Perotti A, Sessa C, Mancuso A, et al. Clinical and pharmacological phase I evaluation of Exherin (ADH-1), a selective anti-N-cadherin peptide in patients with N-cadherin-expressing solid tumours. Ann Oncol. 2009;20 (4):741-5.
    • (2009) Ann Oncol , vol.20 , Issue.4 , pp. 741-745
    • Perotti, A.1    Sessa, C.2    Mancuso, A.3
  • 82
    • 0016824929 scopus 로고
    • Bulk transfer of fluid in the interstitial compartment of mammary tumors
    • Butler TP, Grantham FH, Gullino PM. Bulk transfer of fluid in the interstitial compartment of mammary tumors. Cancer Res. 1975;35(11 Pt 1):3084-8.
    • (1975) Cancer Res , vol.35 , Issue.11 PT 1 , pp. 3084-3088
    • Butler, T.P.1    Grantham, F.H.2    Gullino, P.M.3
  • 83
    • 33244490973 scopus 로고    scopus 로고
    • Peritumoral lymphatic invasion is associated with regional lymph node metastases in prostate adenocarcinoma
    • Roma AA, Magi-Galluzzi C, Kral MA, Jin TT, Klein EA, Zhou M. Peritumoral lymphatic invasion is associated with regional lymph node metastases in prostate adenocarcinoma. Mod Pathol. 2006;19 (3):392-8.
    • (2006) Mod Pathol , vol.19 , Issue.3 , pp. 392-398
    • Roma, A.A.1    Magi-galluzzi, C.2    Kral, M.A.3    Jin, T.T.4    Klein, E.A.5    Zhou, M.6
  • 84
    • 27344443222 scopus 로고    scopus 로고
    • Tumor lymphangiogenesis predicts melanoma metastasis to sentinel lymph nodes
    • Dadras SS, Lange-Asschenfeldt B, Velasco P, et al. Tumor lymphangiogenesis predicts melanoma metastasis to sentinel lymph nodes. Mod Pathol. 2005;18 (9): 1232-42.
    • (2005) Mod Pathol , vol.18 , Issue.9 , pp. 1232-1242
    • Dadras, S.S.1    Lange-asschenfeldt, B.2    Velasco, P.3
  • 85
    • 17144402207 scopus 로고    scopus 로고
    • VEGF-A induces tumor and sentinel lymph node lymphangiogenesis and promotes lymphatic metastasis
    • Hirakawa S, Kodama S, Kunstfeld R, Kajiya K, Brown LF, Detmar M. VEGF-A induces tumor and sentinel lymph node lymphangiogenesis and promotes lymphatic metastasis. J Exp Med. 2005;201 (7): 1089-99.
    • (2005) J Exp Med , vol.201 , Issue.7 , pp. 1089-1099
    • Hirakawa, S.1    Kodama, S.2    Kunstfeld, R.3    Kajiya, K.4    Brown, L.F.5    Detmar, M.6
  • 86
    • 33846180704 scopus 로고    scopus 로고
    • Lymphatic endothelial cells, tumor lymphangiogenesis and metastasis: New insights into intratumoral and peritumoral lymphatics
    • Ji RC. Lymphatic endothelial cells, tumor lymphangiogenesis and metastasis: new insights into intratumoral and peritumoral lymphatics. Cancer Metastasis Rev. 2006;25 (4):677-94.
    • (2006) Cancer Metastasis Rev , vol.25 , Issue.4 , pp. 677-694
    • Ji, R.C.1
  • 87
    • 0016267459 scopus 로고
    • Prognostic significance of the regional lymph node histology in cancer of the breast
    • Tsakraklides V, Olson P, Kersey JH, Good RA. Prognostic significance of the regional lymph node histology in cancer of the breast. Cancer. 1974;34 (4): 1259-67.
    • (1974) Cancer , vol.34 , Issue.4 , pp. 1259-1267
    • Tsakraklides, V.1    Olson, P.2    Kersey, J.H.3    Good, R.A.4
  • 88
    • 0003747375 scopus 로고
    • Significance of occult metastases. A study of breast cancer
    • Pickren JW. Significance of occult metastases. A study of breast cancer. Cancer. 1961;14:1266-71.
    • (1961) Cancer , vol.14 , pp. 1266-1271
    • Pickren, J.W.1
  • 89
    • 0014865396 scopus 로고
    • Metastasis: Quantitative analysis of distribution and fate of tumor embolilabeled with 125 I-5-iodo-2'-deoxyuridine
    • Fidler IJ. Metastasis: quantitative analysis of distribution and fate of tumor embolilabeled with 125 I-5-iodo-2'-deoxyuridine. J Natl Cancer Inst. 1970;45 (4):773-82.
    • (1970) J Natl Cancer Inst , vol.45 , Issue.4 , pp. 773-782
    • Fidler, I.J.1
  • 90
    • 33846083869 scopus 로고    scopus 로고
    • Intravascular cell-to-cell adhesive interactions and bone metastasis
    • Glinsky VV. Intravascular cell-to-cell adhesive interactions and bone metastasis. Cancer Metastasis Rev. 2006;25 (4):531-40.
    • (2006) Cancer Metastasis Rev , vol.25 , Issue.4 , pp. 531-540
    • Glinsky, V.V.1
  • 91
    • 0033559946 scopus 로고    scopus 로고
    • Lysis of tumor cells by natural killer cells in mice is impeded by platelets
    • Nieswandt B, Hafner M, Echtenacher B, Mannel DN. Lysis of tumor cells by natural killer cells in mice is impeded by platelets. Cancer Res. 1999;59 (6): 1295-300.
    • (1999) Cancer Res , vol.59 , Issue.6 , pp. 1295-1300
    • Nieswandt, B.1    Hafner, M.2    Echtenacher, B.3    Mannel, D.N.4
  • 92
    • 9244265563 scopus 로고    scopus 로고
    • Coagulation facilitates tumor cell spreading in the pulmonary vasculature during early metastatic colony formation
    • Im JH, Fu W, Wang H, et al. Coagulation facilitates tumor cell spreading in the pulmonary vasculature during early metastatic colony formation. Cancer Res. 2004;64 (23):8613-9.
    • (2004) Cancer Res , vol.64 , Issue.23 , pp. 8613-8619
    • Im, J.H.1    Fu, W.2    Wang, H.3
  • 93
    • 20344384247 scopus 로고    scopus 로고
    • Mechanical entrapment is insufficient and intercellular adhesion is essential for metastatic cell arrest in distant organs
    • Glinskii OV, Huxley VH, Glinsky GV, Pienta KJ, Raz A, Glinsky VV. Mechanical entrapment is insufficient and intercellular adhesion is essential for metastatic cell arrest in distant organs. Neoplasia. 2005;7 (5):522-7.
    • (2005) Neoplasia , vol.7 , Issue.5 , pp. 522-527
    • Glinskii, O.V.1    Huxley, V.H.2    Glinsky, G.V.3    Pienta, K.J.4    Raz, A.5    Glinsky, V.V.6
  • 94
    • 0026469519 scopus 로고
    • Adhesion molecules and tumor cell interaction with endothelium and subendothelial matrix
    • Honn KV, Tang DG. Adhesion molecules and tumor cell interaction with endothelium and subendothelial matrix. Cancer Metastasis Rev. 1992;11 (3-4): 353-75.
    • (1992) Cancer Metastasis Rev , vol.11 , Issue.3-4 , pp. 353-375
    • Honn, K.V.1    Tang, D.G.2
  • 95
    • 0032554086 scopus 로고    scopus 로고
    • Preferential adhesion of prostate cancer cells to a human bone marrow endothelial cell line
    • Lehr JE, Pienta KJ. Preferential adhesion of prostate cancer cells to a human bone marrow endothelial cell line. J Natl Cancer Inst. 1998;90 (2):118-23.
    • (1998) J Natl Cancer Inst , vol.90 , Issue.2 , pp. 118-123
    • Lehr, J.E.1    Pienta, K.J.2
  • 96
    • 0033559617 scopus 로고    scopus 로고
    • Rapid induction of cytokine and E-selectin expression in the liver in response to metastatic tumor cells
    • Khatib AM, Kontogiannea M, Fallavollita L, Jamison B, Meterissian S, Brodt P. Rapid induction of cytokine and E-selectin expression in the liver in response to metastatic tumor cells. Cancer Res. 1999;59 (6): 1356-61.
    • (1999) Cancer Res , vol.59 , Issue.6 , pp. 1356-1361
    • Khatib, A.M.1    Kontogiannea, M.2    Fallavollita, L.3    Jamison, B.4    Meterissian, S.5    Brodt, P.6
  • 97
    • 12944254582 scopus 로고    scopus 로고
    • IL-18 regulates IL-1 beta-dependent hepatic melanoma metastasis via vascular cell adhesion molecule-1
    • Vidal-Vanaclocha F, Fantuzzi G, Mendoza L, et al. IL-18 regulates IL-1 beta-dependent hepatic melanoma metastasis via vascular cell adhesion molecule-1. Proc Natl Acad Sci USA. 2000;97 (2): 734-9.
    • (2000) Proc Natl Acad Sci USA , vol.97 , Issue.2 , pp. 734-739
    • Vidal-vanaclocha, F.1    Fantuzzi, G.2    Mendoza, L.3
  • 98
    • 0031752956 scopus 로고    scopus 로고
    • Cell shape changes and cytoskeleton reorganization during transendothelial migration of human melanoma cells
    • Voura EB, Sandig M, Kalnins VI, Siu C. Cell shape changes and cytoskeleton reorganization during transendothelial migration of human melanoma cells. Cell Tissue Res. 1998;293 (3):375-87.
    • (1998) Cell Tissue Res , vol.293 , Issue.3 , pp. 375-387
    • Voura, E.B.1    Sandig, M.2    Kalnins, V.I.3    Siu, C.4
  • 99
    • 0032799478 scopus 로고    scopus 로고
    • Cellular expression of green fluorescent protein, coupled with high-resolution in vivo videomicroscopy, to monitor steps in tumor metastasis
    • Naumov GN, Wilson SM, MacDonald IC, et al. Cellular expression of green fluorescent protein, coupled with high-resolution in vivo videomicroscopy, to monitor steps in tumor metastasis. J Cell Sci. 1999;112(Pt 12):1835-42.
    • (1999) J Cell Sci , vol.112 , Issue.PT 12 , pp. 1835-1842
    • Naumov, G.N.1    Wilson, S.M.2    MacDonald, I.C.3
  • 100
    • 0034849958 scopus 로고    scopus 로고
    • Organ-specificity of the extravasation process: An ultrastructural study
    • Paku S, Dome B, Toth R, Timar J. Organ-specificity of the extravasation process: an ultrastructural study. Clin Exp Metastasis. 2000;18 (6):481-92.
    • (2000) Clin Exp Metastasis , vol.18 , Issue.6 , pp. 481-492
    • Paku, S.1    Dome, B.2    Toth, R.3    Timar, J.4
  • 101
    • 0024025705 scopus 로고
    • Organ specificity of tumor metastasis: Role of preferential adhesion, invasion and growth of malignant cells at specific secondary sites
    • Nicolson GL. Organ specificity of tumor metastasis: role of preferential adhesion, invasion and growth of malignant cells at specific secondary sites. Cancer Metastasis Rev. 1988;7 (2):143-88.
    • (1988) Cancer Metastasis Rev , vol.7 , Issue.2 , pp. 143-188
    • Nicolson, G.L.1
  • 102
    • 39549097542 scopus 로고    scopus 로고
    • Blocking alpha2 integrins on rat CC531s colon carcinoma cells prevents operation-induced augmentation of liver metastases outgrowth
    • van der Bij GJ, Oosterling SJ, Bogels M, et al. Blocking alpha2 integrins on rat CC531s colon carcinoma cells prevents operation-induced augmentation of liver metastases outgrowth. Hepatology. 2008;47 (2):532-43.
    • (2008) Hepatology , vol.47 , Issue.2 , pp. 532-543
    • van der Bij, G.J.1    Oosterling, S.J.2    Bogels, M.3
  • 103
    • 0025083071 scopus 로고
    • Critical factors in the biology of human cancer metastasis: Twenty-eighth G.H.A. Clowes memorial award lecture
    • Fidler IJ. Critical factors in the biology of human cancer metastasis: twenty-eighth G.H.A. Clowes memorial award lecture. Cancer Res. 1990;50 (19):6130-8.
    • (1990) Cancer Res , vol.50 , Issue.19 , pp. 6130-6138
    • Fidler, I.J.1
  • 104
    • 78049380554 scopus 로고    scopus 로고
    • The patterns and dynamics of genomic instability in metastatic pancreatic cancer
    • Campbell PJ, Yachida S, Mudie LJ, et al. The patterns and dynamics of genomic instability in metastatic pancreatic cancer. Nature. 2010;467 (7319): 1109-13.
    • (2010) Nature , vol.467 , Issue.7319 , pp. 1109-1113
    • Campbell, P.J.1    Yachida, S.2    Mudie, L.J.3
  • 105
    • 0019939323 scopus 로고
    • Enhanced metastatic potential of tumor cells harvested from spontaneous metastases of heterogeneous murine tumors
    • Talmadge JE, Fidler IJ. Enhanced metastatic potential of tumor cells harvested from spontaneous metastases of heterogeneous murine tumors. J Natl Cancer Inst. 1982;69 (4):975-80.
    • (1982) J Natl Cancer Inst , vol.69 , Issue.4 , pp. 975-980
    • Talmadge, J.E.1    Fidler, I.J.2
  • 106
    • 0022479536 scopus 로고
    • Evidence that intravenously derived murine pulmonary melanoma metastases can originate from the expansion of a single tumor cell
    • Fidler IJ, Talmadge JE. Evidence that intravenously derived murine pulmonary melanoma metastases can originate from the expansion of a single tumor cell. Cancer Res. 1986;46 (10):5167-71.
    • (1986) Cancer Res , vol.46 , Issue.10 , pp. 5167-5171
    • Fidler, I.J.1    Talmadge, J.E.2
  • 107
    • 0034865262 scopus 로고    scopus 로고
    • Tumour dormancy: Findings and hypotheses from clinical research on breast cancer
    • Demicheli R. Tumour dormancy: findings and hypotheses from clinical research on breast cancer. Semin Cancer Biol. 2001;11 (4):297-306.
    • (2001) Semin Cancer Biol , vol.11 , Issue.4 , pp. 297-306
    • Demicheli, R.1
  • 108
    • 35548936833 scopus 로고    scopus 로고
    • Models, mechanisms and clinical evidence for cancer dormancy
    • Aguirre-Ghiso JA. Models, mechanisms and clinical evidence for cancer dormancy. Nat Rev Cancer. 2007;7 (11):834-46.
    • (2007) Nat Rev Cancer , vol.7 , Issue.11 , pp. 834-846
    • Aguirre-ghiso, J.A.1
  • 110
    • 28644432204 scopus 로고    scopus 로고
    • VEGFR1-positive haematopoietic bone marrow progenitors initiate the pre-metastatic niche
    • Kaplan RN, Riba RD, Zacharoulis S, et al. VEGFR1-positive haematopoietic bone marrow progenitors initiate the pre-metastatic niche. Nature. 2005;438 (7069):820-7.
    • (2005) Nature , vol.438 , Issue.7069 , pp. 820-827
    • Kaplan, R.N.1    Riba, R.D.2    Zacharoulis, S.3
  • 111
    • 77955384579 scopus 로고    scopus 로고
    • Gr-1+CD11b+ myeloid cells tip the balance of immune protection to tumor promotion in the premetastatic lung
    • Yan HH, Pickup M, Pang Y, et al. Gr-1+CD11b+ myeloid cells tip the balance of immune protection to tumor promotion in the premetastatic lung. Cancer Res. 2010;70 (15):6139-49.
    • (2010) Cancer Res , vol.70 , Issue.15 , pp. 6139-6149
    • Yan, H.H.1    Pickup, M.2    Pang, Y.3
  • 112
    • 0016413580 scopus 로고
    • Biological behavior of malignant melanoma cells correlated to their survival in vivo
    • Fidler IJ. Biological behavior of malignant melanoma cells correlated to their survival in vivo. Cancer Res. 1975;35 (1):218-24.
    • (1975) Cancer Res , vol.35 , Issue.1 , pp. 218-224
    • Fidler, I.J.1
  • 113
    • 3242805433 scopus 로고
    • The organ selectivity of experimentally induced metastases in rats
    • Sugarbaker ED. The organ selectivity of experimentally induced metastases in rats. Cancer. 1952;5 (3): 606-12.
    • (1952) Cancer , vol.5 , Issue.3 , pp. 606-612
    • Sugarbaker, E.D.1
  • 114
    • 0344591596 scopus 로고
    • An experimental study of preferential metastasis
    • Kinsey DL. An experimental study of preferential metastasis. Cancer. 1960;13:674-6.
    • (1960) Cancer , vol.13 , pp. 674-676
    • Kinsey, D.L.1
  • 116
    • 63049102497 scopus 로고    scopus 로고
    • Parallel progression of primary tumours and metastases
    • Klein CA. Parallel progression of primary tumours and metastases. Nat Rev Cancer. 2009;9 (4):302-12.
    • (2009) Nat Rev Cancer , vol.9 , Issue.4 , pp. 302-312
    • Klein, C.A.1
  • 117
    • 0033777406 scopus 로고    scopus 로고
    • Metastatic liver tumors
    • McCarter MD, Fong Y. Metastatic liver tumors. Semin Surg Oncol. 2000;19 (2):177-88.
    • (2000) Semin Surg Oncol , vol.19 , Issue.2 , pp. 177-188
    • McCarter, M.D.1    Fong, Y.2
  • 118
  • 119
    • 78049398107 scopus 로고    scopus 로고
    • Distant metastasis occurs late during the genetic evolution of pancreatic cancer
    • Yachida S, Jones S, Bozic I, et al. Distant metastasis occurs late during the genetic evolution of pancreatic cancer. Nature. 2010;467 (7319):1114-7.
    • (2010) Nature , vol.467 , Issue.7319 , pp. 1114-1117
    • Yachida, S.1    Jones, S.2    Bozic, I.3
  • 120
    • 41949139438 scopus 로고    scopus 로고
    • Comparative lesion sequencing provides insights into tumor evolution
    • Jones S, Chen WD, Parmigiani G, et al. Comparative lesion sequencing provides insights into tumor evolution. Proc Natl Acad Sci USA. 2008;105 (11): 4283-8.
    • (2008) Proc Natl Acad Sci USA , vol.105 , Issue.11 , pp. 4283-4288
    • Jones, S.1    Chen, W.D.2    Parmigiani, G.3
  • 121
    • 0017167185 scopus 로고
    • The clonal evolution of tumor cell populations
    • Nowell PC. The clonal evolution of tumor cell populations. Science. 1976;194 (4260):23-8.
    • (1976) Science , vol.194 , Issue.4260 , pp. 23-28
    • Nowell, P.C.1
  • 122
    • 0017704436 scopus 로고
    • Metastasis results from preexisting variant cells within a malignant tumor
    • Fidler IJ, Kripke ML. Metastasis results from preexisting variant cells within a malignant tumor. Science. 1977;197 (4306):893-5.
    • (1977) Science , vol.197 , Issue.4306 , pp. 893-895
    • Fidler, I.J.1    Kripke, M.L.2
  • 123
    • 0018123824 scopus 로고
    • Specificity of arrest, survival, and growth of selected metastatic variant cell lines
    • Nicolson GL, Brunson KW, Fidler IJ. Specificity of arrest, survival, and growth of selected metastatic variant cell lines. Cancer Res. 1978;38(11 Pt 2):4105-11.
    • (1978) Cancer Res , vol.38 , Issue.11 PT 2 , pp. 4105-4111
    • Nicolson, G.L.1    Brunson, K.W.2    Fidler, I.J.3
  • 124
    • 0021237842 scopus 로고
    • A human melanoma line heterogeneous with respect to metastatic capacity in athymic nude mice
    • Kozlowski JM, Hart IR, Fidler IJ, Hanna N. A human melanoma line heterogeneous with respect to metastatic capacity in athymic nude mice. J Natl Cancer Inst. 1984;72 (4):913-7.
    • (1984) J Natl Cancer Inst , vol.72 , Issue.4 , pp. 913-917
    • Kozlowski, J.M.1    Hart, I.R.2    Fidler, I.J.3    Hanna, N.4
  • 125
    • 0023790913 scopus 로고
    • Genetic evidence for progressive selection and overgrowth of primary tumors by metastatic cell subpopulations
    • Waghorne C, Thomas M, Lagarde A, Kerbel RS, Breitman ML. Genetic evidence for progressive selection and overgrowth of primary tumors by metastatic cell subpopulations. Cancer Res. 1988;48 (21):6109-14.
    • (1988) Cancer Res , vol.48 , Issue.21 , pp. 6109-6114
    • Waghorne, C.1    Thomas, M.2    Lagarde, A.3    Kerbel, R.S.4    Breitman, M.L.5
  • 126
    • 0342887306 scopus 로고    scopus 로고
    • Genetic heterogeneity and clonal evolution underlying development of asynchronous metastasis in human breast cancer
    • Kuukasjarvi T, Karhu R, Tanner M, et al. Genetic heterogeneity and clonal evolution underlying development of asynchronous metastasis in human breast cancer. Cancer Res. 1997;57 (8):1597-604.
    • (1997) Cancer Res , vol.57 , Issue.8 , pp. 1597-1604
    • Kuukasjarvi, T.1    Karhu, R.2    Tanner, M.3
  • 127
    • 0036990103 scopus 로고    scopus 로고
    • The organ microenvironment and cancer metastasis
    • Fidler IJ. The organ microenvironment and cancer metastasis. Differentiation. 2002;70 (9-10):498-505.
    • (2002) Differentiation , vol.70 , Issue.9-10 , pp. 498-505
    • Fidler, I.J.1
  • 128
    • 3042994720 scopus 로고
    • Increasing metastatic potential is associated with increasing genetic instability of clones isolated from murine neoplasms
    • Cifone MA, Fidler IJ. Increasing metastatic potential is associated with increasing genetic instability of clones isolated from murine neoplasms. Proc Natl Acad Sci USA. 1981;78 (11):6949-52.
    • (1981) Proc Natl Acad Sci USA , vol.78 , Issue.11 , pp. 6949-6952
    • Cifone, M.A.1    Fidler, I.J.2
  • 129
    • 0022399540 scopus 로고
    • Implications of tumor progression on clinical oncology
    • Welch DR, Tomasovic SP. Implications of tumor progression on clinical oncology. Clin Exp Metastasis. 1985;3 (3):151-88.
    • (1985) Clin Exp Metastasis , vol.3 , Issue.3 , pp. 151-188
    • Welch, D.R.1    Tomasovic, S.P.2
  • 130
    • 77955015464 scopus 로고    scopus 로고
    • AACR centennial series: the biology of cancer metastasis: Historical perspective
    • Talmadge JE, Fidler IJ. AACR centennial series: the biology of cancer metastasis: historical perspective. Cancer Res. 2010;70 (14):5649-69.
    • (2010) Cancer Res , vol.70 , Issue.14 , pp. 5649-5669
    • Talmadge, J.E.1    Fidler, I.J.2
  • 131
    • 0038488950 scopus 로고    scopus 로고
    • A multigenic program mediating breast cancer metastasis to bone
    • Kang Y, Siegel PM, Shu W, et al. A multigenic program mediating breast cancer metastasis to bone. Cancer Cell. 2003;3 (6):537-49.
    • (2003) Cancer Cell , vol.3 , Issue.6 , pp. 537-549
    • Kang, Y.1    Siegel, P.M.2    Shu, W.3
  • 132
    • 23144461051 scopus 로고    scopus 로고
    • Genes that mediate breast cancer metastasis to lung
    • Minn AJ, Gupta GP, Siegel PM, et al. Genes that mediate breast cancer metastasis to lung. Nature. 2005;436 (7050):518-24.
    • (2005) Nature , vol.436 , Issue.7050 , pp. 518-524
    • Minn, A.J.1    Gupta, G.P.2    Siegel, P.M.3
  • 133
    • 13844310310 scopus 로고    scopus 로고
    • Gene-expression profiles to predict distant metastasis of lymph-nodenegative primary breast cancer
    • Wang Y, Klijn JG, Zhang Y, et al. Gene-expression profiles to predict distant metastasis of lymph-nodenegative primary breast cancer. Lancet. 2005;365 (9460):671-9.
    • (2005) Lancet , vol.365 , Issue.9460 , pp. 671-679
    • Wang, Y.1    Klijn, J.G.2    Zhang, Y.3
  • 134
    • 0037478605 scopus 로고    scopus 로고
    • Repeated observation of breast tumor subtypes in independent gene expression data sets
    • Sorlie T, Tibshirani R, Parker J, et al. Repeated observation of breast tumor subtypes in independent gene expression data sets. Proc Natl Acad Sci USA. 2003;100 (14):8418-23.
    • (2003) Proc Natl Acad Sci USA , vol.100 , Issue.14 , pp. 8418-8423
    • Sorlie, T.1    Tibshirani, R.2    Parker, J.3
  • 135
    • 0037137519 scopus 로고    scopus 로고
    • A gene-expression signature as a predictor of survival in breast cancer
    • van de Vijver MJ, He YD, Van't Veer LJ, et al. A gene-expression signature as a predictor of survival in breast cancer. N Engl J Med. 2002;347 (25): 1999-2009.
    • (2002) N Engl J Med , vol.347 , Issue.25 , pp. 1999-2009
    • van de Vijver, M.J.1    He, Y.D.2    Van't Veer, L.J.3
  • 136
    • 34547569120 scopus 로고    scopus 로고
    • Gene expression profiling of human lymph node metastases and matched primary breast carcinomas: Clinical implications
    • Suzuki M, Tarin D. Gene expression profiling of human lymph node metastases and matched primary breast carcinomas: clinical implications. Mol Oncol. 2007;1 (2):172-80.
    • (2007) Mol Oncol , vol.1 , Issue.2 , pp. 172-180
    • Suzuki, M.1    Tarin, D.2
  • 137
    • 0035990831 scopus 로고    scopus 로고
    • Comparison of HER-2 status between primary breast cancer and corresponding distant metastatic sites
    • Gancberg D, Di Leo A, Cardoso F, et al. Comparison of HER-2 status between primary breast cancer and corresponding distant metastatic sites. Ann Oncol. 2002;13 (7): 1036-43.
    • (2002) Ann Oncol , vol.13 , Issue.7 , pp. 1036-1043
    • Gancberg, D.1    Di Leo, A.2    Cardoso, F.3
  • 138
    • 0033374678 scopus 로고    scopus 로고
    • Cell adhesion: Old and new questions
    • Hynes RO. Cell adhesion: old and new questions. Trends Cell Biol. 1999;9(12):M33-7.
    • (1999) Trends Cell Biol , vol.9 , Issue.12 , pp. M33-M37
    • Hynes, R.O.1
  • 140
    • 0025777183 scopus 로고
    • The minimal essential sequence for a major cell type-specific adhesion site (CS1) within the alternatively spliced type III connecting segment domain of fibronectin is leucine-aspartic acid-valine
    • Komoriya A, Green LJ, Mervic M, Yamada SS, Yamada KM, Humphries MJ. The minimal essential sequence for a major cell type-specific adhesion site (CS1) within the alternatively spliced type III connecting segment domain of fibronectin is leucine-aspartic acid-valine. J Biol Chem. 1991;266 (23):15075-9.
    • (1991) J Biol Chem , vol.266 , Issue.23 , pp. 15075-15079
    • Komoriya, A.1    Green, L.J.2    Mervic, M.3    Yamada, S.S.4    Yamada, K.M.5    Humphries, M.J.6
  • 141
    • 1542269303 scopus 로고    scopus 로고
    • Integrins: Roles in cancer development and as treatment targets
    • Jin H, Varner J. Integrins: roles in cancer development and as treatment targets. Br J Cancer. 2004;90 (3):561-5.
    • (2004) Br J Cancer , vol.90 , Issue.3 , pp. 561-565
    • Jin, H.1    Varner, J.2
  • 142
    • 34447288669 scopus 로고    scopus 로고
    • Targeting vascular cell migration as a strategy for blocking angiogenesis: The central role of focal adhesion protein tyrosine kinase family
    • Angelucci A, Bologna M. Targeting vascular cell migration as a strategy for blocking angiogenesis: the central role of focal adhesion protein tyrosine kinase family. Curr Pharm Des. 2007;13 (21): 2129-45.
    • (2007) Curr Pharm Des , vol.13 , Issue.21 , pp. 2129-2145
    • Angelucci, A.1    Bologna, M.2
  • 143
    • 0031921101 scopus 로고    scopus 로고
    • Multiple Grb2-mediated integrin-stimulated signaling pathways to ERK2/mitogen-activated protein kinase: Summation of both c-Src- and focal adhesion kinase-initiated tyrosine phosphorylation events
    • Schlaepfer DD, Jones KC, Hunter T. Multiple Grb2-mediated integrin-stimulated signaling pathways to ERK2/mitogen-activated protein kinase: summation of both c-Src- and focal adhesion kinase-initiated tyrosine phosphorylation events. Mol Cell Biol. 1998;18 (5):2571-85.
    • (1998) Mol Cell Biol , vol.18 , Issue.5 , pp. 2571-2585
    • Schlaepfer, D.D.1    Jones, K.C.2    Hunter, T.3
  • 144
    • 34247891506 scopus 로고    scopus 로고
    • Structural basis of integrin regulation and signaling
    • Luo BH, Carman CV, Springer TA. Structural basis of integrin regulation and signaling. Annu Rev Immunol. 2007;25:619-47.
    • (2007) Annu Rev Immunol , vol.25 , pp. 619-647
    • Luo, B.H.1    Carman, C.V.2    Springer, T.A.3
  • 146
    • 0032211804 scopus 로고    scopus 로고
    • ECM signalling: Orchestrating cell behaviour and misbehaviour
    • Lukashev ME, Werb Z. ECM signalling: orchestrating cell behaviour and misbehaviour. Trends Cell Biol. 1998;8 (11):437-41.
    • (1998) Trends Cell Biol , vol.8 , Issue.11 , pp. 437-441
    • Lukashev, M.E.1    Werb, Z.2
  • 147
    • 33847750616 scopus 로고    scopus 로고
    • The alpha6beta4 integrin can regulate ErbB-3 expression: Implications for alpha6beta4 signaling and function
    • Folgiero V, Bachelder RE, Bon G, Sacchi A, Falcioni R, Mercurio AM. The alpha6beta4 integrin can regulate ErbB-3 expression: implications for alpha6beta4 signaling and function. Cancer Res. 2007;67 (4):1645-52.
    • (2007) Cancer Res , vol.67 , Issue.4 , pp. 1645-1652
    • Folgiero, V.1    Bachelder, R.E.2    Bon, G.3    Sacchi, A.4    Falcioni, R.5    Mercurio, A.M.6
  • 148
    • 4344713411 scopus 로고    scopus 로고
    • Changes in extracellular matrix (ECM) and ECM-associated proteins in the metastatic progression of prostate cancer
    • Stewart DA, Cooper CR, Sikes RA. Changes in extracellular matrix (ECM) and ECM-associated proteins in the metastatic progression of prostate cancer. Reprod Biol Endocrinol. 2004;2:2.
    • (2004) Reprod Biol Endocrinol , vol.2 , pp. 2
    • Stewart, D.A.1    Cooper, C.R.2    Sikes, R.A.3
  • 149
    • 0024534130 scopus 로고
    • Regulation of cell adhesion receptors by transforming growth factor-beta. Concomitant regulation of integrins that share a common beta 1 subunit
    • Heino J, Ignotz RA, Hemler ME, Crouse C, Massague J. Regulation of cell adhesion receptors by transforming growth factor-beta. Concomitant regulation of integrins that share a common beta 1 subunit. J Biol Chem. 1989;264 (1):380-8.
    • (1989) J Biol Chem , vol.264 , Issue.1 , pp. 380-388
    • Heino, J.1    Ignotz, R.A.2    Hemler, M.E.3    Crouse, C.4    Massague, J.5
  • 150
    • 58149187467 scopus 로고    scopus 로고
    • The desmoplastic reaction surrounding hepatic colorectal adenocarcinoma metastases aids tumor growth and survival via alphav integrin ligation
    • Conti JA, Kendall TJ, Bateman A, et al. The desmoplastic reaction surrounding hepatic colorectal adenocarcinoma metastases aids tumor growth and survival via alphav integrin ligation. Clin Cancer Res. 2008;14 (20):6405-13.
    • (2008) Clin Cancer Res , vol.14 , Issue.20 , pp. 6405-6413
    • Conti, J.A.1    Kendall, T.J.2    Bateman, A.3
  • 151
    • 49749092745 scopus 로고    scopus 로고
    • Suppression of integrin alphaupsilonbeta6 by RNA interference in colon cancer cells inhibits extracellular matrix degradation through the MAPK pathway
    • Wang J, Zhang Z, Xu K, et al. Suppression of integrin alphaupsilonbeta6 by RNA interference in colon cancer cells inhibits extracellular matrix degradation through the MAPK pathway. Int J Cancer. 2008;123 (6):1311-7.
    • (2008) Int J Cancer , vol.123 , Issue.6 , pp. 1311-1317
    • Wang, J.1    Zhang, Z.2    Xu, K.3
  • 152
    • 0029843947 scopus 로고    scopus 로고
    • Involvement of integrins alpha v beta 3 and alpha v beta 5 in ocular neovascular diseases
    • Friedlander M, Theesfeld CL, Sugita M, et al. Involvement of integrins alpha v beta 3 and alpha v beta 5 in ocular neovascular diseases. Proc Natl Acad Sci USA. 1996;93 (18):9764-9.
    • (1996) Proc Natl Acad Sci USA , vol.93 , Issue.18 , pp. 9764-9769
    • Friedlander, M.1    Theesfeld, C.L.2    Sugita, M.3
  • 153
    • 0028362876 scopus 로고
    • Requirement of vascular integrin alpha v beta 3 for angiogenesis
    • Brooks PC, Clark RA, Cheresh DA. Requirement of vascular integrin alpha v beta 3 for angiogenesis. Science. 1994;264 (5158):569-71.
    • (1994) Science , vol.264 , Issue.5158 , pp. 569-571
    • Brooks, P.C.1    Clark, R.A.2    Cheresh, D.A.3
  • 154
    • 6944228960 scopus 로고    scopus 로고
    • VEGF-A promotes tissue repair-associated lymphatic vessel formation via VEGFR-2 and the alpha-1beta1 and alpha2beta1 integrins
    • Hong YK, Lange-Asschenfeldt B, Velasco P, et al. VEGF-A promotes tissue repair-associated lymphatic vessel formation via VEGFR-2 and the alpha-1beta1 and alpha2beta1 integrins. FASEB J. 2004;18 (10):1111-3.
    • (2004) FASEB J , vol.18 , Issue.10 , pp. 1111-1113
    • Hong, Y.K.1    Lange-asschenfeldt, B.2    Velasco, P.3
  • 156
    • 2942744866 scopus 로고    scopus 로고
    • Antimetastatic properties of RGD-peptidomimetic agents S137 and S247
    • Shannon KE, Keene JL, Settle SL, et al. Antimetastatic properties of RGD-peptidomimetic agents S137 and S247. Clin Exp Metastasis. 2004;21 (2): 129-38.
    • (2004) Clin Exp Metastasis , vol.21 , Issue.2 , pp. 129-138
    • Shannon, K.E.1    Keene, J.L.2    Settle, S.L.3
  • 157
    • 0037728975 scopus 로고    scopus 로고
    • Alphavbeta3 integrin antagonist S247 decreases colon cancer metastasis and angiogenesis and improves survival in mice
    • Reinmuth N, Liu W, Ahmad SA, et al. Alphavbeta3 integrin antagonist S247 decreases colon cancer metastasis and angiogenesis and improves survival in mice. Cancer Res. 2003;63 (9):2079-87.
    • (2003) Cancer Res , vol.63 , Issue.9 , pp. 2079-2087
    • Reinmuth, N.1    Liu, W.2    Ahmad, S.A.3
  • 158
    • 64149106522 scopus 로고    scopus 로고
    • Stimulation of tumor growth and angiogenesis by low concentrations of RGD-mimetic integrin inhibitors
    • Reynolds AR, Hart IR, Watson AR, et al. Stimulation of tumor growth and angiogenesis by low concentrations of RGD-mimetic integrin inhibitors. Nat Med. 2009;15 (4):392-400.
    • (2009) Nat Med , vol.15 , Issue.4 , pp. 392-400
    • Reynolds, A.R.1    Hart, I.R.2    Watson, A.R.3
  • 159
    • 78649416421 scopus 로고    scopus 로고
    • Potential relevance of bell-shaped and u-shaped dose-responses for the therapeutic targeting of angiogenesis in cancer
    • Reynolds AR. Potential relevance of bell-shaped and u-shaped dose-responses for the therapeutic targeting of angiogenesis in cancer. Dose Response. 2009;8 (3):253-84.
    • (2009) Dose Response , vol.8 , Issue.3 , pp. 253-284
    • Reynolds, A.R.1
  • 160
    • 77954941784 scopus 로고    scopus 로고
    • Pharmacodynamic (phase 0) study using etaracizumab in advanced melanoma
    • Moschos SJ, Sander CA, Wang W, et al. Pharmacodynamic (phase 0) study using etaracizumab in advanced melanoma. J Immunother. 2010;33 (3):316-25.
    • (2010) J Immunother , vol.33 , Issue.3 , pp. 316-325
    • Moschos, S.J.1    Sander, C.A.2    Wang, W.3
  • 161
    • 33750453376 scopus 로고    scopus 로고
    • Effects of a monoclonal anti-alphavbeta3 integrin antibody on blood vessels-a pharmacodynamic study
    • Zhang D, Pier T, McNeel DG, Wilding G, Friedl A. Effects of a monoclonal anti-alphavbeta3 integrin antibody on blood vessels-a pharmacodynamic study. Invest New Drugs. 2007;25 (1):49-55.
    • (2007) Invest New Drugs , vol.25 , Issue.1 , pp. 49-55
    • Zhang, D.1    Pier, T.2    McNeel, D.G.3    Wilding, G.4    Friedl, A.5
  • 162
    • 77949394260 scopus 로고    scopus 로고
    • A randomized phase 2 study of etaracizumab, a monoclonal antibody against integrin alpha(v)beta(3), + or - dacarbazine in patients with stage IV metastatic melanoma
    • Hersey P, Sosman J, O'Day S, et al. A randomized phase 2 study of etaracizumab, a monoclonal antibody against integrin alpha(v)beta(3), + or - dacarbazine in patients with stage IV metastatic melanoma. Cancer. 2010;116 (6):1526-34.
    • (2010) Cancer , vol.116 , Issue.6 , pp. 1526-1534
    • Hersey, P.1    Sosman, J.2    O'Day, S.3
  • 163
    • 34948886119 scopus 로고    scopus 로고
    • Effects of Vitaxin, a novel therapeutic in trial for metastatic bone tumors, on osteoclast functions in vitro
    • Gramoun A, Shorey S, Bashutski JD, et al. Effects of Vitaxin, a novel therapeutic in trial for metastatic bone tumors, on osteoclast functions in vitro. J Cell Biochem. 2007;102 (2):341-52.
    • (2007) J Cell Biochem , vol.102 , Issue.2 , pp. 341-352
    • Gramoun, A.1    Shorey, S.2    Bashutski, J.D.3
  • 164
    • 34249087162 scopus 로고    scopus 로고
    • Phase I and correlative biology study of cilengitide in patients with recurrent malignant glioma
    • Nabors LB, Mikkelsen T, Rosenfeld SS, et al. Phase I and correlative biology study of cilengitide in patients with recurrent malignant glioma. J Clin Oncol. 2007;25 (13):1651-7.
    • (2007) J Clin Oncol , vol.25 , Issue.13 , pp. 1651-1657
    • Nabors, L.B.1    Mikkelsen, T.2    Rosenfeld, S.S.3
  • 165
    • 0037457423 scopus 로고    scopus 로고
    • Inhibition of integrin alpha5beta1 function with a small peptide (ATN-161) plus continuous 5-FU infusion reduces colorectal liver metastases and improves survival in mice
    • Stoeltzing O, Liu W, Reinmuth N, et al. Inhibition of integrin alpha5beta1 function with a small peptide (ATN-161) plus continuous 5-FU infusion reduces colorectal liver metastases and improves survival in mice. Int J Cancer. 2003;104 (4):496-503.
    • (2003) Int J Cancer , vol.104 , Issue.4 , pp. 496-503
    • Stoeltzing, O.1    Liu, W.2    Reinmuth, N.3
  • 166
    • 33749577839 scopus 로고    scopus 로고
    • A non-RGD-based integrin binding peptide (ATN-161) blocks breast cancer growth and metastasis in vivo
    • Khalili P, Arakelian A, Chen G, et al. A non-RGD-based integrin binding peptide (ATN-161) blocks breast cancer growth and metastasis in vivo. Mol Cancer Ther. 2006;5 (9):2271-80.
    • (2006) Mol Cancer Ther , vol.5 , Issue.9 , pp. 2271-2280
    • Khalili, P.1    Arakelian, A.2    Chen, G.3
  • 167
    • 0023946733 scopus 로고
    • Role of adhesive proteins in platelet tumor interaction in vitro and metastasis formation in vivo
    • Karpatkin S, Pearlstein E, Ambrogio C, Coller BS. Role of adhesive proteins in platelet tumor interaction in vitro and metastasis formation in vivo. J Clin Invest. 1988;81 (4):1012-9.
    • (1988) J Clin Invest , vol.81 , Issue.4 , pp. 1012-1019
    • Karpatkin, S.1    Pearlstein, E.2    Ambrogio, C.3    Coller, B.S.4
  • 168
    • 0033364731 scopus 로고    scopus 로고
    • Soluble fibrin augments platelet/tumor cell adherence in vitro and in vivo, and enhances experimental metastasis
    • Biggerstaff JP, Seth N, Amirkhosravi A, et al. Soluble fibrin augments platelet/tumor cell adherence in vitro and in vivo, and enhances experimental metastasis. Clin Exp Metastasis. 1999;17 (8): 723-30.
    • (1999) Clin Exp Metastasis , vol.17 , Issue.8 , pp. 723-730
    • Biggerstaff, J.P.1    Seth, N.2    Amirkhosravi, A.3
  • 169
    • 0032836245 scopus 로고    scopus 로고
    • Blockade of GpIIb/IIIa inhibits the release of vascular endothelial growth factor (VEGF) from tumor cell-activated platelets and experimental metastasis
    • Amirkhosravi A, Amaya M, Siddiqui F, Biggerstaff JP, Meyer TV, Francis JL. Blockade of GpIIb/IIIa inhibits the release of vascular endothelial growth factor (VEGF) from tumor cell-activated platelets and experimental metastasis. Platelets. 1999;10 (5): 285-92.
    • (1999) Platelets , vol.10 , Issue.5 , pp. 285-292
    • Amirkhosravi, A.1    Amaya, M.2    Siddiqui, F.3    Biggerstaff, J.P.4    Meyer, T.V.5    Francis, J.L.6
  • 170
    • 36048961429 scopus 로고    scopus 로고
    • Role of von Willebrand factor in tumor metastasis
    • Terraube V, Marx I, Denis CV. Role of von Willebrand factor in tumor metastasis. Thromb Res. 2007;120 Suppl 2:S64-70.
    • (2007) Thromb Res , vol.120 , pp. S64-S70
    • Terraube, V.1    Marx, I.2    Denis, C.V.3
  • 171
    • 24744464311 scopus 로고    scopus 로고
    • Shear stress induced release of von Willebrand factor and thrombospondin-1 in HUVEC extracellular matrix enhances breast tumour cell adhesion
    • Gomes N, Legrand C, Fauvel-Lafeve F. Shear stress induced release of von Willebrand factor and thrombospondin-1 in HUVEC extracellular matrix enhances breast tumour cell adhesion. Clin Exp Metastasis. 2005;22 (3):215-23.
    • (2005) Clin Exp Metastasis , vol.22 , Issue.3 , pp. 215-223
    • Gomes, N.1    Legrand, C.2    Fauvel-lafeve, F.3
  • 172
    • 0033972059 scopus 로고    scopus 로고
    • Intravascular origin of metastasis from the proliferation of endothelium-attached tumor cells: A new model for metastasis
    • Al-Mehdi AB, Tozawa K, Fisher AB, Shientag L, Lee A, Muschel RJ. Intravascular origin of metastasis from the proliferation of endothelium-attached tumor cells: a new model for metastasis. Nat Med. 2000;6 (1): 100-2.
    • (2000) Nat Med , vol.6 , Issue.1 , pp. 100-102
    • Al-mehdi, A.B.1    Tozawa, K.2    Fisher, A.B.3    Shientag, L.4    Lee, A.5    Muschel, R.J.6
  • 173
    • 0038418255 scopus 로고    scopus 로고
    • Intravascular metastatic cancer cell homotypic aggregation at the sites of primary attachment to the endothelium
    • Glinsky VV, Glinsky GV, Glinskii OV, et al. Intravascular metastatic cancer cell homotypic aggregation at the sites of primary attachment to the endothelium. Cancer Res. 2003;63 (13):3805-11.
    • (2003) Cancer Res , vol.63 , Issue.13 , pp. 3805-3811
    • Glinsky, V.V.1    Glinsky, G.V.2    Glinskii, O.V.3
  • 175
    • 33644557719 scopus 로고    scopus 로고
    • Emerging insights in tissue factor-dependent signaling events
    • Versteeg HH, Ruf W. Emerging insights in tissue factor-dependent signaling events. Semin Thromb Hemost. 2006;32 (1):24-32.
    • (2006) Semin Thromb Hemost , vol.32 , Issue.1 , pp. 24-32
    • Versteeg, H.H.1    Ruf, W.2
  • 176
    • 0034650704 scopus 로고    scopus 로고
    • Tissue factor expression in human colorectal carcinoma: Correlation with hepatic metastasis and impact on prognosis
    • Seto S, Onodera H, Kaido T, et al. Tissue factor expression in human colorectal carcinoma: correlation with hepatic metastasis and impact on prognosis. Cancer. 2000;88 (2):295-301.
    • (2000) Cancer , vol.88 , Issue.2 , pp. 295-301
    • Seto, S.1    Onodera, H.2    Kaido, T.3
  • 177
    • 32244438720 scopus 로고    scopus 로고
    • Tissue factor pathway inhibitor: Structure, biology and involvement in disease
    • Lwaleed BA, Bass PS. Tissue factor pathway inhibitor: structure, biology and involvement in disease. J Pathol. 2006;208 (3):327-39.
    • (2006) J Pathol , vol.208 , Issue.3 , pp. 327-339
    • Lwaleed, B.A.1    Bass, P.S.2
  • 178
    • 0030020590 scopus 로고    scopus 로고
    • In situ detection of tissue factor in vascular endothelial cells: Correlation with the malignant phenotype of human breast disease
    • Contrino J, Hair G, Kreutzer DL, Rickles FR. In situ detection of tissue factor in vascular endothelial cells: correlation with the malignant phenotype of human breast disease. Nat Med. 1996;2 (2): 209-15.
    • (1996) Nat Med , vol.2 , Issue.2 , pp. 209-215
    • Contrino, J.1    Hair, G.2    Kreutzer, D.L.3    Rickles, F.R.4
  • 179
    • 60149104694 scopus 로고    scopus 로고
    • The novel anticoagulants: Entering a new era
    • Bounameaux H. The novel anticoagulants: entering a new era. Swiss Med Wkly. 2009;139 (5-6):60-4.
    • (2009) Swiss Med Wkly , vol.139 , Issue.5-6 , pp. 60-64
    • Bounameaux, H.1
  • 180
    • 0036463453 scopus 로고    scopus 로고
    • Novel drug development opportunities for heparin
    • Lever R, Page CP. Novel drug development opportunities for heparin. Nat Rev Drug Discov. 2002;1 (2):140-8.
    • (2002) Nat Rev Drug Discov , vol.1 , Issue.2 , pp. 140-148
    • Lever, R.1    Page, C.P.2
  • 181
    • 33847291915 scopus 로고    scopus 로고
    • Mechanisms of heparin induced anti-cancer activity in experimental cancer models
    • Niers TM, Klerk CP, DiNisio M, et al. Mechanisms of heparin induced anti-cancer activity in experimental cancer models. Crit Rev Oncol Hematol. 2007;61(3): 195-207.
    • (2007) Crit Rev Oncol Hematol , vol.61 , Issue.3 , pp. 195-207
    • Niers, T.M.1    Klerk, C.P.2    DiNisio, M.3
  • 182
    • 0035109328 scopus 로고    scopus 로고
    • The complex effects of heparins on cancer progression and metastasis in experimental studies
    • Smorenburg SM, Van Noorden CJ. The complex effects of heparins on cancer progression and metastasis in experimental studies. Pharmacol Rev. 2001;53 (1):93-105.
    • (2001) Pharmacol Rev , vol.53 , Issue.1 , pp. 93-105
    • Smorenburg, S.M.1    Van Noorden, C.J.2
  • 184
    • 26444566779 scopus 로고    scopus 로고
    • Differential metastasis inhibition by clinically relevant levels of heparins-correlation with selectin inhibition, not antithrombotic activity
    • Stevenson JL, Choi SH, Varki A. Differential metastasis inhibition by clinically relevant levels of heparins-correlation with selectin inhibition, not antithrombotic activity. Clin Cancer Res. 2005;11(19 Pt 1):7003-11.
    • (2005) Clin Cancer Res , vol.11 , Issue.19 PT 1 , pp. 7003-7011
    • Stevenson, J.L.1    Choi, S.H.2    Varki, A.3
  • 185
    • 1842463681 scopus 로고    scopus 로고
    • Antimetastatic effect of tinzaparin, a low-molecular-weight heparin
    • Amirkhosravi A, Mousa SA, Amaya M, Francis JL. Antimetastatic effect of tinzaparin, a low-molecular-weight heparin. J Thromb Haemost. 2003;1 (9): 1972-6.
    • (2003) J Thromb Haemost , vol.1 , Issue.9 , pp. 1972-1976
    • Amirkhosravi, A.1    Mousa, S.A.2    Amaya, M.3    Francis, J.L.4
  • 186
    • 23944442968 scopus 로고    scopus 로고
    • Selective antimetastatic effect of heparins in preclinical human melanoma models is based on inhibition of migration and microvascular arrest
    • Bereczky B, Gilly R, Raso E, Vago A, Timar J, Tovari J. Selective antimetastatic effect of heparins in preclinical human melanoma models is based on inhibition of migration and microvascular arrest. Clin Exp Metastasis. 2005;22 (1):69-76.
    • (2005) Clin Exp Metastasis , vol.22 , Issue.1 , pp. 69-76
    • Bereczky, B.1    Gilly, R.2    Raso, E.3    Vago, A.4    Timar, J.5    Tovari, J.6
  • 188
    • 3042704507 scopus 로고    scopus 로고
    • Low molecular weight heparin, therapy with dalteparin, and survival in advanced cancer: The fragmin advanced malignancy outcome study (FAMOUS)
    • Kakkar AK, Levine MN, Kadziola Z, et al. Low molecular weight heparin, therapy with dalteparin, and survival in advanced cancer: the fragmin advanced malignancy outcome study (FAMOUS). J Clin Oncol. 2004;22 (10):1944-8.
    • (2004) J Clin Oncol , vol.22 , Issue.10 , pp. 1944-1948
    • Kakkar, A.K.1    Levine, M.N.2    Kadziola, Z.3
  • 190
    • 0035853111 scopus 로고    scopus 로고
    • Heparin and cancer revisited: Mechanistic connections involving platelets, P-selectin, carcinoma mucins, and tumor metastasis
    • Borsig L, Wong R, Feramisco J, Nadeau DR, Varki NM, Varki A. Heparin and cancer revisited: mechanistic connections involving platelets, P-selectin, carcinoma mucins, and tumor metastasis. Proc Natl Acad Sci USA. 2001;98 (6):3352-7.
    • (2001) Proc Natl Acad Sci USA , vol.98 , Issue.6 , pp. 3352-3357
    • Borsig, L.1    Wong, R.2    Feramisco, J.3    Nadeau, D.R.4    Varki, N.M.5    Varki, A.6
  • 191
    • 0027990931 scopus 로고
    • A novel in vitro assay system for transendothelial tumor cell invasion: Significance of E-selectin and alpha 3 integrin in the transendothelial invasion by HT1080 fibrosarcoma cells
    • Okada T, Okuno H, Mitsui Y. A novel in vitro assay system for transendothelial tumor cell invasion: significance of E-selectin and alpha 3 integrin in the transendothelial invasion by HT1080 fibrosarcoma cells. Clin Exp Metastasis. 1994;12 (4):305-14.
    • (1994) Clin Exp Metastasis , vol.12 , Issue.4 , pp. 305-314
    • Okada, T.1    Okuno, H.2    Mitsui, Y.3
  • 192
    • 0028598886 scopus 로고
    • The relative roles of vitronectin receptor, E-selectin and alpha 4 beta 1 in cancer cell adhesion to interleukin-1-treated endothelial cells
    • Lafrenie RM, Gallo S, Podor TJ, Buchanan MR, Orr FW. The relative roles of vitronectin receptor, E-selectin and alpha 4 beta 1 in cancer cell adhesion to interleukin-1-treated endothelial cells. Eur J Cancer. 1994;30A(14):2151-8.
    • (1994) Eur J Cancer , vol.30 A , Issue.14 , pp. 2151-2158
    • Lafrenie, R.M.1    Gallo, S.2    Podor, T.J.3    Buchanan, M.R.4    Orr, F.W.5
  • 193
    • 0033106217 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha stimulates attachment of small cell lung carcinoma to endothelial cells
    • Sheski FD, Natarajan V, Pottratz ST. Tumor necrosis factor-alpha stimulates attachment of small cell lung carcinoma to endothelial cells. J Lab Clin Med. 1999;133 (3):265-73.
    • (1999) J Lab Clin Med , vol.133 , Issue.3 , pp. 265-273
    • Sheski, F.D.1    Natarajan, V.2    Pottratz, S.T.3
  • 194
    • 26844469068 scopus 로고    scopus 로고
    • Shear stress and shear rate differentially affect the multi-step process of leukocyte-facilitated melanoma adhesion
    • Liang S, Slattery MJ, Dong C. Shear stress and shear rate differentially affect the multi-step process of leukocyte-facilitated melanoma adhesion. Exp Cell Res. 2005;310 (2):282-92.
    • (2005) Exp Cell Res , vol.310 , Issue.2 , pp. 282-292
    • Liang, S.1    Slattery, M.J.2    Dong, C.3
  • 195
    • 24044472715 scopus 로고    scopus 로고
    • Characterization of the host proinflammatory response to tumor cells during the initial stages of liver metastasis
    • Khatib AM, Auguste P, Fallavollita L, et al. Characterization of the host proinflammatory response to tumor cells during the initial stages of liver metastasis. Am J Pathol. 2005;167 (3):749-59.
    • (2005) Am J Pathol , vol.167 , Issue.3 , pp. 749-759
    • Khatib, A.M.1    Auguste, P.2    Fallavollita, L.3
  • 196
    • 0029858031 scopus 로고    scopus 로고
    • Selectins and their ligands: Current concepts and controversies
    • Kansas GS. Selectins and their ligands: current concepts and controversies. Blood. 1996;88 (9): 3259-87.
    • (1996) Blood , vol.88 , Issue.9 , pp. 3259-3287
    • Kansas, G.S.1
  • 197
    • 0029153610 scopus 로고
    • Differential colon cancer cell adhesion to E-, P-, and L-selectin: Role of mucin-type glycoproteins
    • Mannori G, Crottet P, Cecconi O, et al. Differential colon cancer cell adhesion to E-, P-, and L-selectin: role of mucin-type glycoproteins. Cancer Res. 1995;55 (19):4425-31.
    • (1995) Cancer Res , vol.55 , Issue.19 , pp. 4425-4431
    • Mannori, G.1    Crottet, P.2    Cecconi, O.3
  • 198
    • 73349141180 scopus 로고    scopus 로고
    • Alpha 1,3 fucosyltransferases are master regulators of prostate cancer cell trafficking
    • Barthel SR, Wiese GK, Cho J, et al. Alpha 1,3 fucosyltransferases are master regulators of prostate cancer cell trafficking. Proc Natl Acad Sci USA. 2009;106 (46): 19491-6.
    • (2009) Proc Natl Acad Sci USA , vol.106 , Issue.46 , pp. 19491-19496
    • Barthel, S.R.1    Wiese, G.K.2    Cho, J.3
  • 199
    • 0031940687 scopus 로고    scopus 로고
    • Selectins and mechanisms of signal transduction
    • Crockett-Torabi E. Selectins and mechanisms of signal transduction. J Leukoc Biol. 1998;63 (1):1-14.
    • (1998) J Leukoc Biol , vol.63 , Issue.1 , pp. 1-14
    • Crockett-torabi, E.1
  • 200
    • 0030029220 scopus 로고    scopus 로고
    • Redirection of tumor metastasis by expression of E-selectin in vivo
    • Biancone L, Araki M, Araki K, Vassalli P, Stamenkovic I. Redirection of tumor metastasis by expression of E-selectin in vivo. J Exp Med. 1996;183 (2):581-7.
    • (1996) J Exp Med , vol.183 , Issue.2 , pp. 581-587
    • Biancone, L.1    Araki, M.2    Araki, K.3    Vassalli, P.4    Stamenkovic, I.5
  • 202
    • 0037133173 scopus 로고    scopus 로고
    • Synergistic effects of L- and P-selectin in facilitating tumor metastasis can involve non-mucin ligands and implicate leukocytes as enhancers of metastasis
    • Borsig L, Wong R, Hynes RO, Varki NM, Varki A. Synergistic effects of L- and P-selectin in facilitating tumor metastasis can involve non-mucin ligands and implicate leukocytes as enhancers of metastasis. Proc Natl Acad Sci USA. 2002;99 (4):2193-8.
    • (2002) Proc Natl Acad Sci USA , vol.99 , Issue.4 , pp. 2193-2198
    • Borsig, L.1    Wong, R.2    Hynes, R.O.3    Varki, N.M.4    Varki, A.5
  • 203
    • 77956614939 scopus 로고    scopus 로고
    • Selectins promote tumor metastasis
    • Laubli H, Borsig L. Selectins promote tumor metastasis. Semin Cancer Biol. 2010;20 (3):169-77.
    • (2010) Semin Cancer Biol , vol.20 , Issue.3 , pp. 169-177
    • Laubli, H.1    Borsig, L.2
  • 204
    • 0346496053 scopus 로고    scopus 로고
    • Evidence of porcine and human endothelium activation by cancer-associated carbohydrates expressed on glycoproteins and tumour cells
    • Glinskii OV, Turk JR, Pienta KJ, Huxley VH, Glinsky VV. Evidence of porcine and human endothelium activation by cancer-associated carbohydrates expressed on glycoproteins and tumour cells. J Physiol. 2004;554(Pt 1):89-99.
    • (2004) J Physiol , vol.554 , Issue.PT 1 , pp. 89-99
    • Glinskii, O.V.1    Turk, J.R.2    Pienta, K.J.3    Huxley, V.H.4    Glinsky, V.V.5
  • 205
    • 33846964873 scopus 로고    scopus 로고
    • Galectin-3 interaction with Thomsen-Friedenreich disaccharide on cancer-associated MUC1 causes increased cancer cell endothelial adhesion
    • Yu LG, Andrews N, Zhao Q, et al. Galectin-3 interaction with Thomsen-Friedenreich disaccharide on cancer-associated MUC1 causes increased cancer cell endothelial adhesion. J Biol Chem. 2007;282 (1):773-81.
    • (2007) J Biol Chem , vol.282 , Issue.1 , pp. 773-781
    • Yu, L.G.1    Andrews, N.2    Zhao, Q.3
  • 206
    • 0031784245 scopus 로고    scopus 로고
    • Animal lectins as cell adhesion molecules
    • Kaltner H, Stierstorfer B. Animal lectins as cell adhesion molecules. Acta Anat (Basel). 1998;161 (1-4): 162-79.
    • (1998) Acta Anat (Basel) , vol.161 , Issue.1-4 , pp. 162-179
    • Kaltner, H.1    Stierstorfer, B.2
  • 207
    • 0031928731 scopus 로고    scopus 로고
    • Metastasis of human colon cancer is altered by modifying expression of the beta-galactoside-binding protein galectin 3
    • Bresalier RS, Mazurek N, Sternberg LR, et al. Metastasis of human colon cancer is altered by modifying expression of the beta-galactoside-binding protein galectin 3. Gastroenterology. 1998;115 (2): 287-96.
    • (1998) Gastroenterology , vol.115 , Issue.2 , pp. 287-296
    • Bresalier, R.S.1    Mazurek, N.2    Sternberg, L.R.3
  • 208
    • 0037423206 scopus 로고    scopus 로고
    • MDA-MB-435 human breast carcinoma cell homo- and heterotypic adhesion under flow conditions is mediated in part by Thomsen-Friedenreich antigen-galectin-3 interactions
    • Khaldoyanidi SK, Glinsky VV, Sikora L, et al. MDA-MB-435 human breast carcinoma cell homo- and heterotypic adhesion under flow conditions is mediated in part by Thomsen-Friedenreich antigen-galectin-3 interactions. J Biol Chem. 2003;278 (6): 4127-34.
    • (2003) J Biol Chem , vol.278 , Issue.6 , pp. 4127-4134
    • Khaldoyanidi, S.K.1    Glinsky, V.V.2    Sikora, L.3
  • 209
    • 0034660854 scopus 로고    scopus 로고
    • Cimetidine inhibits cancer cell adhesion to endothelial cells and prevents metastasis by blocking E-selectin expression
    • Kobayashi K, Matsumoto S, Morishima T, Kawabe T, Okamoto T. Cimetidine inhibits cancer cell adhesion to endothelial cells and prevents metastasis by blocking E-selectin expression. Cancer Res. 2000;60 (14):3978-84.
    • (2000) Cancer Res , vol.60 , Issue.14 , pp. 3978-3984
    • Kobayashi, K.1    Matsumoto, S.2    Morishima, T.3    Kawabe, T.4    Okamoto, T.5
  • 210
    • 0347123435 scopus 로고    scopus 로고
    • Mucins in cancer: Protection and control of the cell surface
    • Hollingsworth MA, Swanson BJ. Mucins in cancer: protection and control of the cell surface. Nat Rev Cancer. 2004;4 (1):45-60.
    • (2004) Nat Rev Cancer , vol.4 , Issue.1 , pp. 45-60
    • Hollingsworth, M.A.1    Swanson, B.J.2
  • 211
    • 0031882792 scopus 로고    scopus 로고
    • Lack of selectin-dependent adhesion in prostate cancer cells expressing sialyl Le(x)
    • Satoh M, Numahata K, Kawamura S, Saito S, Orikasa S. Lack of selectin-dependent adhesion in prostate cancer cells expressing sialyl Le(x). Int J Urol. 1998;5 (1):86-91.
    • (1998) Int J Urol , vol.5 , Issue.1 , pp. 86-91
    • Satoh, M.1    Numahata, K.2    Kawamura, S.3    Saito, S.4    Orikasa, S.5
  • 212
    • 0038603921 scopus 로고    scopus 로고
    • The role of selectins in inflammation and disease
    • Ley K. The role of selectins in inflammation and disease. Trends Mol Med. 2003;9 (6):263-8.
    • (2003) Trends Mol Med , vol.9 , Issue.6 , pp. 263-268
    • Ley, K.1
  • 213
    • 0038615922 scopus 로고    scopus 로고
    • A disaccharide precursor of sialyl Lewis X inhibits metastatic potential of tumor cells
    • Fuster MM, Brown JR, Wang L, Esko JD. A disaccharide precursor of sialyl Lewis X inhibits metastatic potential of tumor cells. Cancer Res. 2003;63 (11):2775-81.
    • (2003) Cancer Res , vol.63 , Issue.11 , pp. 2775-2781
    • Fuster, M.M.1    Brown, J.R.2    Wang, L.3    Esko, J.D.4
  • 214
    • 33646750715 scopus 로고    scopus 로고
    • A disaccharide-based inhibitor of glycosylation attenuates metastatic tumor cell dissemination
    • Brown JR, Fuster MM, Li R, Varki N, Glass CA, Esko JD. A disaccharide-based inhibitor of glycosylation attenuates metastatic tumor cell dissemination. Clin Cancer Res. 2006;12 (9):2894-901.
    • (2006) Clin Cancer Res , vol.12 , Issue.9 , pp. 2894-2901
    • Brown, J.R.1    Fuster, M.M.2    Li, R.3    Varki, N.4    Glass, C.A.5    Esko, J.D.6
  • 215
    • 0028887370 scopus 로고
    • Involvement of the very late antigen 4 integrin on melanoma in interleukin 1-augmented experimental metastases
    • Garofalo A, Chirivi RG, Foglieni C, et al. Involvement of the very late antigen 4 integrin on melanoma in interleukin 1-augmented experimental metastases. Cancer Res. 1995;55 (2):414-9.
    • (1995) Cancer Res , vol.55 , Issue.2 , pp. 414-419
    • Garofalo, A.1    Chirivi, R.G.2    Foglieni, C.3
  • 216
    • 48349130370 scopus 로고    scopus 로고
    • A highly bone marrow metastatic murine breast cancer model established through in vivo selection exhibits enhanced anchorage-independent growth and cell migration mediated by ICAM-1
    • Takahashi M, Furihata M, Akimitsu N, et al. A highly bone marrow metastatic murine breast cancer model established through in vivo selection exhibits enhanced anchorage-independent growth and cell migration mediated by ICAM-1. Clin Exp Metastasis. 2008;25 (5):517-29.
    • (2008) Clin Exp Metastasis , vol.25 , Issue.5 , pp. 517-529
    • Takahashi, M.1    Furihata, M.2    Akimitsu, N.3
  • 217
    • 0026071846 scopus 로고
    • Monoclonal antibodies against intercellular adhesion molecule 1 prolong cardiac allograft survival in cynomolgus monkeys
    • Flavin T, Ivens K, Rothlein R, et al. Monoclonal antibodies against intercellular adhesion molecule 1 prolong cardiac allograft survival in cynomolgus monkeys. Transplant Proc. 1991;23(1 Pt 1):533-4.
    • (1991) Transplant Proc , vol.23 , Issue.1 PT 1 , pp. 533-534
    • Flavin, T.1    Ivens, K.2    Rothlein, R.3
  • 218
    • 0027413809 scopus 로고
    • A phase I trial of immunosuppression with anti-ICAM-1 (CD54) mAb in renal allograft recipients
    • discussion 772-763
    • Haug CE, Colvin RB, Delmonico FL, et al. A phase I trial of immunosuppression with anti-ICAM-1 (CD54) mAb in renal allograft recipients. Transplantation. 1993; 55 (4):766-72. discussion 772-763.
    • (1993) Transplantation , vol.55 , Issue.4 , pp. 766-772
    • Haug, C.E.1    Colvin, R.B.2    Delmonico, F.L.3
  • 219
    • 78149253585 scopus 로고    scopus 로고
    • Acute anti-inflammatory approaches to ischemic stroke
    • del Zoppo GJ. Acute anti-inflammatory approaches to ischemic stroke. Ann NY Acad Sci. 2010;1207: 143-8.
    • (2010) Ann NY Acad Sci , vol.1207 , pp. 143-148
    • del Zoppo, G.J.1
  • 220
    • 0030272760 scopus 로고    scopus 로고
    • To stick or not to stick: The new leukocyte homing paradigm
    • Dunon D, Piali L, Imhof BA. To stick or not to stick: the new leukocyte homing paradigm. Curr Opin Cell Biol. 1996;8 (5):714-23.
    • (1996) Curr Opin Cell Biol , vol.8 , Issue.5 , pp. 714-723
    • Dunon, D.1    Piali, L.2    Imhof, B.A.3
  • 221
    • 0029911784 scopus 로고    scopus 로고
    • Role of platelet-endothelial cell adhesion molecule (PECAM) in platelet adhesion/ aggregation over injured but not denuded endothelium in vivo and ex vivo
    • Rosenblum WI, Nelson GH, Wormley B, Werner P, Wang J, Shih CC. Role of platelet-endothelial cell adhesion molecule (PECAM) in platelet adhesion/ aggregation over injured but not denuded endothelium in vivo and ex vivo. Stroke. 1996;27 (4): 709-11.
    • (1996) Stroke , vol.27 , Issue.4 , pp. 709-711
    • Rosenblum, W.I.1    Nelson, G.H.2    Wormley, B.3    Werner, P.4    Wang, J.5    Shih, C.C.6
  • 222
    • 78649889485 scopus 로고    scopus 로고
    • Vascular endothelial platelet endothelial cell adhesion molecule 1 (PECAM-1) regulates advanced metastatic progression
    • DeLisser H, Liu Y, Desprez PY, et al. Vascular endothelial platelet endothelial cell adhesion molecule 1 (PECAM-1) regulates advanced metastatic progression. Proc Natl Acad Sci USA. 2010;107 (43):18616-21.
    • (2010) Proc Natl Acad Sci USA , vol.107 , Issue.43 , pp. 18616-18621
    • DeLisser, H.1    Liu, Y.2    Desprez, P.Y.3
  • 223
    • 0034144269 scopus 로고    scopus 로고
    • Chemokines: A new classification system and their role in immunity
    • Zlotnik A, Yoshie O. Chemokines: a new classification system and their role in immunity. Immunity. 2000;12 (2):121-7.
    • (2000) Immunity , vol.12 , Issue.2 , pp. 121-127
    • Zlotnik, A.1    Yoshie, O.2
  • 224
    • 36148979810 scopus 로고    scopus 로고
    • CXC chemokines located in the 4q21 region are up-regulated in breast cancer
    • Bieche I, Chavey C, Andrieu C, et al. CXC chemokines located in the 4q21 region are up-regulated in breast cancer. Endocr Relat Cancer. 2007;14 (4): 1039-52.
    • (2007) Endocr Relat Cancer , vol.14 , Issue.4 , pp. 1039-1052
    • Bieche, I.1    Chavey, C.2    Andrieu, C.3
  • 225
    • 44349193400 scopus 로고    scopus 로고
    • Stepping out of the flow: Capillary extravasation in cancer metastasis
    • Miles FL, Pruitt FL, van Golen KL, Cooper CR. Stepping out of the flow: capillary extravasation in cancer metastasis. Clin Exp Metastasis. 2008;25 (4): 305-24.
    • (2008) Clin Exp Metastasis , vol.25 , Issue.4 , pp. 305-324
    • Miles, F.L.1    Pruitt, F.L.2    van Golen, K.L.3    Cooper, C.R.4
  • 226
    • 55349148665 scopus 로고    scopus 로고
    • The chemokine receptor CX3CR1 is involved in the neural tropism and malignant behavior of pancreatic ductal adenocarcinoma
    • Marchesi F, Piemonti L, Fedele G, et al. The chemokine receptor CX3CR1 is involved in the neural tropism and malignant behavior of pancreatic ductal adenocarcinoma. Cancer Res. 2008;68 (21):9060-9.
    • (2008) Cancer Res , vol.68 , Issue.21 , pp. 9060-9069
    • Marchesi, F.1    Piemonti, L.2    Fedele, G.3
  • 227
    • 0141685979 scopus 로고    scopus 로고
    • Expression pattern of CXC chemokine receptor-4 is correlated with lymph node metastasis in human invasive ductal carcinoma
    • Kato M, Kitayama J, Kazama S, Nagawa H. Expression pattern of CXC chemokine receptor-4 is correlated with lymph node metastasis in human invasive ductal carcinoma. Breast Cancer Res. 2003;5(5):R144-50.
    • (2003) Breast Cancer Res , vol.5 , Issue.5 , pp. R144-R150
    • Kato, M.1    Kitayama, J.2    Kazama, S.3    Nagawa, H.4
  • 228
    • 0038498102 scopus 로고    scopus 로고
    • NF-kappaB promotes breast cancer cell migration and metastasis by inducing the expression of the chemokine receptor CXCR4
    • Helbig G, Christopherson 2nd KW, Bhat-Nakshatri P, et al. NF-kappaB promotes breast cancer cell migration and metastasis by inducing the expression of the chemokine receptor CXCR4. J Biol Chem. 2003;278 (24):21631-8.
    • (2003) J Biol Chem , vol.278 , Issue.24 , pp. 21631-21638
    • Helbig, G.1    Christopherson, K.W.2    Bhat-nakshatri, P.3
  • 229
    • 33646867374 scopus 로고    scopus 로고
    • Expression of chemokine receptors predicts the site of metastatic relapse in patients with axillary node positive primary breast cancer
    • Andre F, Cabioglu N, Assi H, et al. Expression of chemokine receptors predicts the site of metastatic relapse in patients with axillary node positive primary breast cancer. Ann Oncol. 2006;17 (6):945-51.
    • (2006) Ann Oncol , vol.17 , Issue.6 , pp. 945-951
    • Andre, F.1    Cabioglu, N.2    Assi, H.3
  • 230
    • 3142512612 scopus 로고    scopus 로고
    • Molecular characterization of the tumor microenvironment in breast cancer
    • Allinen M, Beroukhim R, Cai L, et al. Molecular characterization of the tumor microenvironment in breast cancer. Cancer Cell. 2004;6 (1):17-32.
    • (2004) Cancer Cell , vol.6 , Issue.1 , pp. 17-32
    • Allinen, M.1    Beroukhim, R.2    Cai, L.3
  • 231
    • 35648945337 scopus 로고    scopus 로고
    • CXCR7 (RDC1) promotes breast and lung tumor growth in vivo and is expressed on tumor-associated vasculature
    • Miao Z, Luker KE, Summers BC, et al. CXCR7 (RDC1) promotes breast and lung tumor growth in vivo and is expressed on tumor-associated vasculature. Proc Natl Acad Sci USA. 2007;104 (40): 15735-40.
    • (2007) Proc Natl Acad Sci USA , vol.104 , Issue.40 , pp. 15735-15740
    • Miao, Z.1    Luker, K.E.2    Summers, B.C.3
  • 232
    • 23244440503 scopus 로고    scopus 로고
    • Prediction of lymph node metastasis in colorectal carcinoma by expression of chemokine receptor CCR7
    • Gunther K, Leier J, Henning G, et al. Prediction of lymph node metastasis in colorectal carcinoma by expression of chemokine receptor CCR7. Int J Cancer. 2005;116 (5):726-33.
    • (2005) Int J Cancer , vol.116 , Issue.5 , pp. 726-733
    • Gunther, K.1    Leier, J.2    Henning, G.3
  • 233
    • 34249774277 scopus 로고    scopus 로고
    • Autologous chemotaxis as a mechanism of tumor cell homing to lymphatics via interstitial flow and autocrine CCR7 signaling
    • Shields JD, Fleury ME, Yong C, Tomei AA, Randolph GJ, Swartz MA. Autologous chemotaxis as a mechanism of tumor cell homing to lymphatics via interstitial flow and autocrine CCR7 signaling. Cancer Cell. 2007;11 (6):526-38.
    • (2007) Cancer Cell , vol.11 , Issue.6 , pp. 526-538
    • Shields, J.D.1    Fleury, M.E.2    Yong, C.3    Tomei, A.A.4    Randolph, G.J.5    Swartz, M.A.6
  • 234
    • 9244234390 scopus 로고    scopus 로고
    • CXCR4 regulates growth of both primary and metastatic breast cancer
    • Smith MC, Luker KE, Garbow JR, et al. CXCR4 regulates growth of both primary and metastatic breast cancer. Cancer Res. 2004;64 (23):8604-12.
    • (2004) Cancer Res , vol.64 , Issue.23 , pp. 8604-8612
    • Smith, M.C.1    Luker, K.E.2    Garbow, J.R.3
  • 235
    • 3042616145 scopus 로고    scopus 로고
    • Inhibition of breast cancer metastasis by selective synthetic polypeptide against CXCR4
    • Liang Z, Wu T, Lou H, et al. Inhibition of breast cancer metastasis by selective synthetic polypeptide against CXCR4. Cancer Res. 2004;64 (12):4302-8.
    • (2004) Cancer Res , vol.64 , Issue.12 , pp. 4302-4308
    • Liang, Z.1    Wu, T.2    Lou, H.3
  • 236
    • 33746685587 scopus 로고    scopus 로고
    • Characterization of the molecular pharmacology of AMD3100: A specific antagonist of the G-protein coupled chemokine receptor, CXCR4
    • Fricker SP, Anastassov V, Cox J, et al. Characterization of the molecular pharmacology of AMD3100: a specific antagonist of the G-protein coupled chemokine receptor, CXCR4. Biochem Pharmacol. 2006;72 (5):588-96.
    • (2006) Biochem Pharmacol , vol.72 , Issue.5 , pp. 588-596
    • Fricker, S.P.1    Anastassov, V.2    Cox, J.3
  • 237
    • 2942654586 scopus 로고    scopus 로고
    • A single treatment with microcapsules containing a CXCR4 antagonist suppresses pulmonary metastasis of murine melanoma
    • Takenaga M, Tamamura H, Hiramatsu K, et al. A single treatment with microcapsules containing a CXCR4 antagonist suppresses pulmonary metastasis of murine melanoma. Biochem Biophys Res Commun. 2004;320 (1):226-32.
    • (2004) Biochem Biophys Res Commun , vol.320 , Issue.1 , pp. 226-232
    • Takenaga, M.1    Tamamura, H.2    Hiramatsu, K.3
  • 238
    • 79953163995 scopus 로고    scopus 로고
    • Proteolytic networks in cancer
    • Mason SD, Joyce JA. Proteolytic networks in cancer. Trends Cell Biol. 2011;21 (4):228-37.
    • (2011) Trends Cell Biol , vol.21 , Issue.4 , pp. 228-237
    • Mason, S.D.1    Joyce, J.A.2
  • 239
    • 31344458952 scopus 로고    scopus 로고
    • Structure and function of matrix metalloproteinases and TIMPs
    • Nagase H, Visse R, Murphy G. Structure and function of matrix metalloproteinases and TIMPs. Cardiovasc Res. 2006;69 (3):562-73.
    • (2006) Cardiovasc Res , vol.69 , Issue.3 , pp. 562-573
    • Nagase, H.1    Visse, R.2    Murphy, G.3
  • 240
    • 0345643514 scopus 로고    scopus 로고
    • Regulation of matrix metalloproteinase expression in tumor invasion
    • Westermarck J, Kahari VM. Regulation of matrix metalloproteinase expression in tumor invasion. FASEB J. 1999;13 (8):781-92.
    • (1999) FASEB J , vol.13 , Issue.8 , pp. 781-792
    • Westermarck, J.1    Kahari, V.M.2
  • 241
    • 0032782127 scopus 로고    scopus 로고
    • Stimulation of angiogenesis through cathepsin B inactivation of the tissue inhibitors of matrix metalloproteinases
    • Kostoulas G, Lang A, Nagase H, Baici A. Stimulation of angiogenesis through cathepsin B inactivation of the tissue inhibitors of matrix metalloproteinases. FEBS Lett. 1999;455 (3):286-90.
    • (1999) FEBS Lett , vol.455 , Issue.3 , pp. 286-290
    • Kostoulas, G.1    Lang, A.2    Nagase, H.3    Baici, A.4
  • 242
    • 0035227794 scopus 로고    scopus 로고
    • The matrix metalloproteinase (MMP) and tissue inhibitor of metalloproteinase (TIMP) genes. Transcriptional and posttranscriptional regulation, signal transduction and cell-type-specific expression
    • Vincenti MP. The matrix metalloproteinase (MMP) and tissue inhibitor of metalloproteinase (TIMP) genes. Transcriptional and posttranscriptional regulation, signal transduction and cell-type-specific expression. Methods Mol Biol. 2001;151:121-48.
    • (2001) Methods Mol Biol , vol.151 , pp. 121-148
    • Vincenti, M.P.1
  • 243
    • 0028795147 scopus 로고
    • The human tumor cell-derived collagenase stimulatory factor (renamed EMMPRIN) is a member of the immunoglobulin superfamily
    • Biswas C, Zhang Y, DeCastro R, et al. The human tumor cell-derived collagenase stimulatory factor (renamed EMMPRIN) is a member of the immunoglobulin superfamily. Cancer Res. 1995;55 (2): 434-9.
    • (1995) Cancer Res , vol.55 , Issue.2 , pp. 434-439
    • Biswas, C.1    Zhang, Y.2    DeCastro, R.3
  • 244
    • 24744449559 scopus 로고    scopus 로고
    • Targeting of urokinase plasminogen activator receptor in human pancreatic carcinoma cells inhibits c-Met- and insulin-like growth factor-I receptor-mediated migration and invasion and orthotopic tumor growth in mice
    • Bauer TW, Liu W, Fan F, et al. Targeting of urokinase plasminogen activator receptor in human pancreatic carcinoma cells inhibits c-Met- and insulin-like growth factor-I receptor-mediated migration and invasion and orthotopic tumor growth in mice. Cancer Res. 2005;65 (17):7775-81.
    • (2005) Cancer Res , vol.65 , Issue.17 , pp. 7775-7781
    • Bauer, T.W.1    Liu, W.2    Fan, F.3
  • 245
    • 2542432100 scopus 로고    scopus 로고
    • Expression of extracellular matrix metalloproteases inducer on micrometastatic and primary mammary carcinoma cells
    • Reimers N, Zafrakas K, Assmann V, et al. Expression of extracellular matrix metalloproteases inducer on micrometastatic and primary mammary carcinoma cells. Clin Cancer Res. 2004;10 (10):3422-8.
    • (2004) Clin Cancer Res , vol.10 , Issue.10 , pp. 3422-3428
    • Reimers, N.1    Zafrakas, K.2    Assmann, V.3
  • 246
    • 0035266353 scopus 로고    scopus 로고
    • Regulation of MMP-1 and MMP-2 production through CD 147/extracellular matrix metalloproteinase inducer interactions
    • Sun J, Hemler ME. Regulation of MMP-1 and MMP-2 production through CD 147/extracellular matrix metalloproteinase inducer interactions. Cancer Res. 2001;61 (5):2276-81.
    • (2001) Cancer Res , vol.61 , Issue.5 , pp. 2276-2281
    • Sun, J.1    Hemler, M.E.2
  • 247
    • 17144422889 scopus 로고    scopus 로고
    • Extracellular matrix metalloproteinase inducer stimulates tumor angiogenesis by elevating vascular endothelial cell growth factor and matrix metalloproteinases
    • Tang Y, Nakada MT, Kesavan P, et al. Extracellular matrix metalloproteinase inducer stimulates tumor angiogenesis by elevating vascular endothelial cell growth factor and matrix metalloproteinases. Cancer Res. 2005;65 (8):3193-9.
    • (2005) Cancer Res , vol.65 , Issue.8 , pp. 3193-3199
    • Tang, Y.1    Nakada, M.T.2    Kesavan, P.3
  • 248
    • 0021030118 scopus 로고
    • Human skin fibroblast collagenase inhibitor. Comparative studies in human connective tissues, serum, and amniotic fluid
    • Welgus HG, Stricklin GP. Human skin fibroblast collagenase inhibitor. Comparative studies in human connective tissues, serum, and amniotic fluid. J Biol Chem. 1983;258 (20):12259-64.
    • (1983) J Biol Chem , vol.258 , Issue.20 , pp. 12259-12264
    • Welgus, H.G.1    Stricklin, G.P.2
  • 249
    • 34347329150 scopus 로고    scopus 로고
    • RECK modulates Notch signaling during cortical neurogenesis by regulating ADAM10 activity
    • Muraguchi T, Takegami Y, Ohtsuka T, et al. RECK modulates Notch signaling during cortical neurogenesis by regulating ADAM10 activity. Nat Neurosci. 2007;10 (7): 838-45.
    • (2007) Nat Neurosci , vol.10 , Issue.7 , pp. 838-845
    • Muraguchi, T.1    Takegami, Y.2    Ohtsuka, T.3
  • 250
    • 0029129995 scopus 로고
    • Distinct pattern of matrix metalloproteinase 9 and tissue inhibitor of metalloproteinase 1 mRNA expression in human colorectal cancer and liver metastases
    • Zeng ZS, Guillem JG. Distinct pattern of matrix metalloproteinase 9 and tissue inhibitor of metalloproteinase 1 mRNA expression in human colorectal cancer and liver metastases. Br J Cancer. 1995;72 (3):575-82.
    • (1995) Br J Cancer , vol.72 , Issue.3 , pp. 575-582
    • Zeng, Z.S.1    Guillem, J.G.2
  • 251
    • 0029950355 scopus 로고    scopus 로고
    • Expression, subcellular distribution and plasma membrane binding of cathepsin B and gelatinases in bone metastatic tissue
    • Arkona C, Wiederanders B. Expression, subcellular distribution and plasma membrane binding of cathepsin B and gelatinases in bone metastatic tissue. Biol Chem. 1996;377 (11):695-702.
    • (1996) Biol Chem , vol.377 , Issue.11 , pp. 695-702
    • Arkona, C.1    Wiederanders, B.2
  • 252
    • 0037005993 scopus 로고    scopus 로고
    • Matrix metalloproteinase activity, bone matrix turnover, and tumor cell proliferation in prostate cancer bone metastasis
    • Nemeth JA, Yousif R, Herzog M, et al. Matrix metalloproteinase activity, bone matrix turnover, and tumor cell proliferation in prostate cancer bone metastasis. J Natl Cancer Inst. 2002;94 (1):17-25.
    • (2002) J Natl Cancer Inst , vol.94 , Issue.1 , pp. 17-25
    • Nemeth, J.A.1    Yousif, R.2    Herzog, M.3
  • 253
    • 67649392519 scopus 로고    scopus 로고
    • Expression of extracellular matrix molecules in brain metastasis
    • Yoshida S, Takahashi H. Expression of extracellular matrix molecules in brain metastasis. J Surg Oncol. 2009;100 (1):65-8.
    • (2009) J Surg Oncol , vol.100 , Issue.1 , pp. 65-68
    • Yoshida, S.1    Takahashi, H.2
  • 254
    • 60949088751 scopus 로고    scopus 로고
    • Identification of brain- and bone-specific breast cancer metastasis genes
    • Klein A, Olendrowitz C, Schmutzler R, et al. Identification of brain- and bone-specific breast cancer metastasis genes. Cancer Lett. 2009;276 (2): 212-20.
    • (2009) Cancer Lett , vol.276 , Issue.2 , pp. 212-220
    • Klein, A.1    Olendrowitz, C.2    Schmutzler, R.3
  • 255
    • 48649097728 scopus 로고    scopus 로고
    • Cathepsin G enhances mammary tumor-induced osteolysis by generating soluble receptor activator of nuclear factor-kappaB ligand
    • Wilson TJ, Nannuru KC, Futakuchi M, Sadanandam A, Singh RK. Cathepsin G enhances mammary tumor-induced osteolysis by generating soluble receptor activator of nuclear factor-kappaB ligand. Cancer Res. 2008;68 (14):5803-11.
    • (2008) Cancer Res , vol.68 , Issue.14 , pp. 5803-5811
    • Wilson, T.J.1    Nannuru, K.C.2    Futakuchi, M.3    Sadanandam, A.4    Singh, R.K.5
  • 256
    • 77951709842 scopus 로고    scopus 로고
    • Matrix metalloproteinase (MMP)-13 regulates mammary tumor-induced osteolysis by activating MMP9 and transforming growth factor-beta signaling at the tumor-bone interface
    • Nannuru KC, Futakuchi M, Varney ML, Vincent TM, Marcusson EG, Singh RK. Matrix metalloproteinase (MMP)-13 regulates mammary tumor-induced osteolysis by activating MMP9 and transforming growth factor-beta signaling at the tumor-bone interface. Cancer Res. 2010;70 (9): 3494-504.
    • (2010) Cancer Res , vol.70 , Issue.9 , pp. 3494-3504
    • Nannuru, K.C.1    Futakuchi, M.2    Varney, M.L.3    Vincent, T.M.4    Marcusson, E.G.5    Singh, R.K.6
  • 257
    • 67649791971 scopus 로고    scopus 로고
    • Denosumab treatment of prostate cancer with bone metastases and increased urine N-telopeptide levels after therapy with intravenous bisphosphonates: Results of a randomized phase II trial
    • discussion 515-506
    • Fizazi K, Bosserman L, Gao G, Skacel T, Markus R. Denosumab treatment of prostate cancer with bone metastases and increased urine N-telopeptide levels after therapy with intravenous bisphosphonates: results of a randomized phase II trial. J Urol. 2009; 182 (2):509-15. discussion 515-506.
    • (2009) J Urol , vol.182 , Issue.2 , pp. 509-515
    • Fizazi, K.1    Bosserman, L.2    Gao, G.3    Skacel, T.4    Markus, R.5
  • 258
    • 0343051765 scopus 로고    scopus 로고
    • In situ detection of matrix metalloproteinase-2 (MMP2) and the metalloproteinase inhibitor TIMP2 transcripts in human primary hepatocellular carcinoma and in liver metastasis
    • Musso O, Theret N, Campion JP, et al. In situ detection of matrix metalloproteinase-2 (MMP2) and the metalloproteinase inhibitor TIMP2 transcripts in human primary hepatocellular carcinoma and in liver metastasis. J Hepatol. 1997;26 (3):593-605.
    • (1997) J Hepatol , vol.26 , Issue.3 , pp. 593-605
    • Musso, O.1    Theret, N.2    Campion, J.P.3
  • 259
    • 0032031861 scopus 로고    scopus 로고
    • Reduced angiogenesis and tumor progression in gelatinase A-deficient mice
    • Itoh T, Tanioka M, Yoshida H, Yoshioka T, Nishimoto H, Itohara S. Reduced angiogenesis and tumor progression in gelatinase A-deficient mice. Cancer Res. 1998;58 (5): 1048-51.
    • (1998) Cancer Res , vol.58 , Issue.5 , pp. 1048-1051
    • Itoh, T.1    Tanioka, M.2    Yoshida, H.3    Yoshioka, T.4    Nishimoto, H.5    Itohara, S.6
  • 260
    • 0032789885 scopus 로고    scopus 로고
    • Experimental metastasis is suppressed in MMP-9-deficient mice
    • Itoh T, Tanioka M, Matsuda H, et al. Experimental metastasis is suppressed in MMP-9-deficient mice. Clin Exp Metastasis. 1999;17 (2):177-81.
    • (1999) Clin Exp Metastasis , vol.17 , Issue.2 , pp. 177-181
    • Itoh, T.1    Tanioka, M.2    Matsuda, H.3
  • 261
    • 0028999498 scopus 로고
    • H-31 human breast cancer cells stimulate type I collage-nase production in osteoblast-like cells and induce bone resorption
    • Ohishi K, Fujita N, Morinaga Y, Tsuruo T. H-31 human breast cancer cells stimulate type I collage-nase production in osteoblast-like cells and induce bone resorption. Clin Exp Metastasis. 1995;13 (4):287-95.
    • (1995) Clin Exp Metastasis , vol.13 , Issue.4 , pp. 287-295
    • Ohishi, K.1    Fujita, N.2    Morinaga, Y.3    Tsuruo, T.4
  • 262
    • 33644545381 scopus 로고    scopus 로고
    • Tumour microenvironment - opinion: Validating matrix metalloproteinases as drug targets and anti-targets for cancer therapy
    • Overall CM, Kleifeld O. Tumour microenvironment - opinion: validating matrix metalloproteinases as drug targets and anti-targets for cancer therapy. Nat Rev Cancer. 2006;6 (3):227-39.
    • (2006) Nat Rev Cancer , vol.6 , Issue.3 , pp. 227-239
    • Overall, C.M.1    Kleifeld, O.2
  • 263
    • 36148994693 scopus 로고    scopus 로고
    • The other side of MMPs: Protective roles in tumor progression
    • Martin MD, Matrisian LM. The other side of MMPs: protective roles in tumor progression. Cancer Metastasis Rev. 2007;26 (3-4):717-24.
    • (2007) Cancer Metastasis Rev , vol.26 , Issue.3-4 , pp. 717-724
    • Martin, M.D.1    Matrisian, L.M.2
  • 264
    • 18144417470 scopus 로고    scopus 로고
    • Human breast cancer cell-mediated bone collagen degradation requires plasminogen activation and matrix metalloproteinase activity
    • Morgan H, Hill PA. Human breast cancer cell-mediated bone collagen degradation requires plasminogen activation and matrix metalloproteinase activity. Cancer Cell Inst. 2005;5 (1):1.
    • (2005) Cancer Cell Inst , vol.5 , Issue.1 , pp. 1
    • Morgan, H.1    Hill, P.A.2
  • 265
    • 33144457649 scopus 로고    scopus 로고
    • Plasmin modulates vascular endothelial growth factor-A-mediated angiogenesis during wound repair
    • Roth D, Piekarek M, Paulsson M, et al. Plasmin modulates vascular endothelial growth factor-A-mediated angiogenesis during wound repair. Am J Pathol. 2006;168 (2):670-84.
    • (2006) Am J Pathol , vol.168 , Issue.2 , pp. 670-684
    • Roth, D.1    Piekarek, M.2    Paulsson, M.3
  • 266
    • 0038022616 scopus 로고    scopus 로고
    • Flavonoids inhibit VEGF/bFGF-induced angiogenesis in vitro by inhibiting the matrixdegrading proteases
    • Kim MH. Flavonoids inhibit VEGF/bFGF-induced angiogenesis in vitro by inhibiting the matrixdegrading proteases. J Cell Biochem. 2003;89 (3): 529-38.
    • (2003) J Cell Biochem , vol.89 , Issue.3 , pp. 529-538
    • Kim, M.H.1
  • 267
    • 0001071353 scopus 로고    scopus 로고
    • Cancer invasion and tissue remodeling-cooperation of protease systems and cell types
    • Dano K, Romer J, Nielsen BS, et al. Cancer invasion and tissue remodeling-cooperation of protease systems and cell types. APMIS. 1999;107 (1):120-7.
    • (1999) APMIS , vol.107 , Issue.1 , pp. 120-127
    • Dano, K.1    Romer, J.2    Nielsen, B.S.3
  • 268
    • 0025052018 scopus 로고
    • Cloning and expression of the receptor for human urokinase plasminogen activator, a central molecule in cell surface, plasmin dependent proteolysis
    • Roldan AL, Cubellis MV, Masucci MT, et al. Cloning and expression of the receptor for human urokinase plasminogen activator, a central molecule in cell surface, plasmin dependent proteolysis. EMBO J. 1990;9 (2):467-74.
    • (1990) EMBO J , vol.9 , Issue.2 , pp. 467-474
    • Roldan, A.L.1    Cubellis, M.V.2    Masucci, M.T.3
  • 269
    • 53249122047 scopus 로고    scopus 로고
    • Urokinase plasminogen activator receptor choreographs multiple ligand interactions: Implications for tumor progression and therapy
    • Mazar AP. Urokinase plasminogen activator receptor choreographs multiple ligand interactions: implications for tumor progression and therapy. Clin Cancer Res. 2008;14 (18):5649-55.
    • (2008) Clin Cancer Res , vol.14 , Issue.18 , pp. 5649-5655
    • Mazar, A.P.1
  • 270
    • 0035127868 scopus 로고    scopus 로고
    • The role and regulation of urokinase-type plasminogen activator receptor gene expression in cancer invasion and metastasis
    • Wang Y. The role and regulation of urokinase-type plasminogen activator receptor gene expression in cancer invasion and metastasis. Med Res Rev. 2001;21 (2):146-70.
    • (2001) Med Res Rev , vol.21 , Issue.2 , pp. 146-170
    • Wang, Y.1
  • 271
    • 7844244311 scopus 로고    scopus 로고
    • Urokinase type plasminogen activator receptor expression in colorectal neoplasms
    • Suzuki S, Hayashi Y, Wang Y, et al. Urokinase type plasminogen activator receptor expression in colorectal neoplasms. Gut. 1998;43 (6):798-805.
    • (1998) Gut , vol.43 , Issue.6 , pp. 798-805
    • Suzuki, S.1    Hayashi, Y.2    Wang, Y.3
  • 272
    • 68549133353 scopus 로고    scopus 로고
    • Targeting the urokinase plasminogen activator receptor with a monoclonal antibody impairs the growth of human colorectal cancer in the liver
    • Van Buren G, Gray MJ, Dallas NA, et al. Targeting the urokinase plasminogen activator receptor with a monoclonal antibody impairs the growth of human colorectal cancer in the liver. Cancer. 2009;115 (14):3360-8.
    • (2009) Cancer , vol.115 , Issue.14 , pp. 3360-3368
    • Van Buren, G.1    Gray, M.J.2    Dallas, N.A.3
  • 273
    • 77957797120 scopus 로고    scopus 로고
    • An antiurokinase plasminogen activator receptor antibody (ATN-658) blocks prostate cancer invasion, migration, growth, and experimental skeletal metastasis in vitro and in vivo
    • Rabbani SA, Ateeq B, Arakelian A, et al. An antiurokinase plasminogen activator receptor antibody (ATN-658) blocks prostate cancer invasion, migration, growth, and experimental skeletal metastasis in vitro and in vivo. Neoplasia. 2010;12 (10): 778-88.
    • (2010) Neoplasia , vol.12 , Issue.10 , pp. 778-788
    • Rabbani, S.A.1    Ateeq, B.2    Arakelian, A.3
  • 274
    • 0021045628 scopus 로고
    • Antibodies to plasminogen activator inhibit human tumor metastasis
    • Ossowski L, Reich E. Antibodies to plasminogen activator inhibit human tumor metastasis. Cell. 1983;35(3 Pt 2):611-9.
    • (1983) Cell , vol.35 , Issue.3 PT 2 , pp. 611-619
    • Ossowski, L.1    Reich, E.2
  • 275
    • 20244381689 scopus 로고    scopus 로고
    • Effects of blocking urokinase receptor signaling by antisense oligonucleotides in a mouse model of experimental prostate cancer bone metastases
    • Margheri F, D'Alessio S, Serrati S, et al. Effects of blocking urokinase receptor signaling by antisense oligonucleotides in a mouse model of experimental prostate cancer bone metastases. Gene Ther. 2005;12 (8):702-14.
    • (2005) Gene Ther , vol.12 , Issue.8 , pp. 702-714
    • Margheri, F.1    D'Alessio, S.2    Serrati, S.3
  • 276
    • 0030739571 scopus 로고    scopus 로고
    • Homozygous mutations in the plasminogen gene of two unrelated girls with ligneous conjunctivitis
    • Schuster V, Mingers AM, Seidenspinner S, Nussgens Z, Pukrop T, Kreth HW. Homozygous mutations in the plasminogen gene of two unrelated girls with ligneous conjunctivitis. Blood. 1997;90 (3):958-66.
    • (1997) Blood , vol.90 , Issue.3 , pp. 958-966
    • Schuster, V.1    Mingers, A.M.2    Seidenspinner, S.3    Nussgens, Z.4    Pukrop, T.5    Kreth, H.W.6
  • 277
    • 25144437350 scopus 로고    scopus 로고
    • A6, a urokinase plasminogen activator (uPA)-derived peptide in patients with advanced gynecologic cancer: A phase I trial
    • Berkenblit A, Matulonis UA, Kroener JF, et al. A6, a urokinase plasminogen activator (uPA)-derived peptide in patients with advanced gynecologic cancer: a phase I trial. Gynecol Oncol. 2005;99 (1):50-7.
    • (2005) Gynecol Oncol , vol.99 , Issue.1 , pp. 50-57
    • Berkenblit, A.1    Matulonis, U.A.2    Kroener, J.F.3
  • 278
    • 34250167944 scopus 로고    scopus 로고
    • Selective inhibition of ADAM metalloproteases as a novel approach for modulating ErbB pathways in cancer
    • Fridman JS, Caulder E, Hansbury M, et al. Selective inhibition of ADAM metalloproteases as a novel approach for modulating ErbB pathways in cancer. Clin Cancer Res. 2007;13 (6):1892-902.
    • (2007) Clin Cancer Res , vol.13 , Issue.6 , pp. 1892-1902
    • Fridman, J.S.1    Caulder, E.2    Hansbury, M.3
  • 279
    • 33846817495 scopus 로고    scopus 로고
    • Targeting TACE-dependent EGFR ligand shedding in breast cancer
    • Kenny PA, Bissell MJ. Targeting TACE-dependent EGFR ligand shedding in breast cancer. J Clin Invest. 2007;117 (2):337-45.
    • (2007) J Clin Invest , vol.117 , Issue.2 , pp. 337-345
    • Kenny, P.A.1    Bissell, M.J.2
  • 280
    • 19644367756 scopus 로고    scopus 로고
    • A secreted form of ADAM9 promotes carcinoma invasion through tumor-stromal interactions
    • Mazzocca A, Coppari R, De Franco R, et al. A secreted form of ADAM9 promotes carcinoma invasion through tumor-stromal interactions. Cancer Res. 2005;65 (11):4728-38.
    • (2005) Cancer Res , vol.65 , Issue.11 , pp. 4728-4738
    • Mazzocca, A.1    Coppari, R.2    De Franco, R.3
  • 281
    • 0034682773 scopus 로고    scopus 로고
    • The thrombospondin motif of aggrecanase-1 (ADAMTS-4) is critical for aggrecan substrate recognition and cleavage
    • Tortorella M, Pratta M, Liu RQ, et al. The thrombospondin motif of aggrecanase-1 (ADAMTS-4) is critical for aggrecan substrate recognition and cleavage. J Biol Chem. 2000;275 (33):25791-7.
    • (2000) J Biol Chem , vol.275 , Issue.33 , pp. 25791-25797
    • Tortorella, M.1    Pratta, M.2    Liu, R.Q.3
  • 282
    • 0035807348 scopus 로고    scopus 로고
    • Mutations in a member of the ADAMTS gene family cause thrombotic thrombocytopenic purpura
    • Levy GG, Nichols WC, Lian EC, et al. Mutations in a member of the ADAMTS gene family cause thrombotic thrombocytopenic purpura. Nature. 2001;413 (6855):488-94.
    • (2001) Nature , vol.413 , Issue.6855 , pp. 488-494
    • Levy, G.G.1    Nichols, W.C.2    Lian, E.C.3
  • 283
    • 56749133149 scopus 로고    scopus 로고
    • The ADAMs: Signalling scissors in the tumour microenvironment
    • Murphy G. The ADAMs: signalling scissors in the tumour microenvironment. Nat Rev Cancer. 2008;8 (12):929-41.
    • (2008) Nat Rev Cancer , vol.8 , Issue.12 , pp. 929-941
    • Murphy, G.1
  • 284
    • 1442358746 scopus 로고    scopus 로고
    • Distinct roles for ADAM10 and ADAM17 in ectodomain shedding of six EGFR ligands
    • Sahin U, Weskamp G, Kelly K, et al. Distinct roles for ADAM10 and ADAM17 in ectodomain shedding of six EGFR ligands. J Cell Biol. 2004;164 (5):769-79.
    • (2004) J Cell Biol , vol.164 , Issue.5 , pp. 769-779
    • Sahin, U.1    Weskamp, G.2    Kelly, K.3
  • 285
    • 33745765680 scopus 로고    scopus 로고
    • Identification of ADAM10 as a major source of HER2 ectodomain sheddase activity in HER2 overexpressing breast cancer cells
    • Liu PC, Liu X, Li Y, et al. Identification of ADAM10 as a major source of HER2 ectodomain sheddase activity in HER2 overexpressing breast cancer cells. Cancer Biol Ther. 2006;5 (6):657-64.
    • (2006) Cancer Biol Ther , vol.5 , Issue.6 , pp. 657-664
    • Liu, P.C.1    Liu, X.2    Li, Y.3
  • 286
    • 31544476294 scopus 로고    scopus 로고
    • TIMP-3 deficiency in the host, but not in the tumor, enhances tumor growth and angiogenesis
    • Cruz-Munoz W, Kim I, Khokha R. TIMP-3 deficiency in the host, but not in the tumor, enhances tumor growth and angiogenesis. Oncogene. 2006;25 (4):650-5.
    • (2006) Oncogene , vol.25 , Issue.4 , pp. 650-655
    • Cruz-munoz, W.1    Kim, I.2    Khokha, R.3
  • 287
    • 33846643454 scopus 로고    scopus 로고
    • Cysteine cathepsins and the cutting edge of cancer invasion
    • Gocheva V, Joyce JA. Cysteine cathepsins and the cutting edge of cancer invasion. Cell Cycle. 2007;6 (1):60-4.
    • (2007) Cell Cycle , vol.6 , Issue.1 , pp. 60-64
    • Gocheva, V.1    Joyce, J.A.2
  • 288
    • 2342603891 scopus 로고    scopus 로고
    • Cathepsin cysteine proteases are effectors of invasive growth and angiogenesis during multistage tumorigenesis
    • Joyce JA, Baruch A, Chehade K, et al. Cathepsin cysteine proteases are effectors of invasive growth and angiogenesis during multistage tumorigenesis. Cancer Cell. 2004;5 (5):443-53.
    • (2004) Cancer Cell , vol.5 , Issue.5 , pp. 443-453
    • Joyce, J.A.1    Baruch, A.2    Chehade, K.3
  • 289
    • 77957855881 scopus 로고    scopus 로고
    • Specialized roles for cysteine cathepsins in health and disease
    • Reiser J, Adair B, Reinheckel T. Specialized roles for cysteine cathepsins in health and disease. J Clin Invest. 2010;120 (10):3421-31.
    • (2010) J Clin Invest , vol.120 , Issue.10 , pp. 3421-3431
    • Reiser, J.1    Adair, B.2    Reinheckel, T.3
  • 290
    • 0029240263 scopus 로고
    • Mammalian cysteine protease inhibitors: Biochemical properties and possible roles in tumor progression
    • Calkins CC, Sloane BF. Mammalian cysteine protease inhibitors: biochemical properties and possible roles in tumor progression. Biol Chem Hoppe Seyler. 1995;376 (2):71-80.
    • (1995) Biol Chem Hoppe Seyler , vol.376 , Issue.2 , pp. 71-80
    • Calkins, C.C.1    Sloane, B.F.2
  • 291
    • 0033802696 scopus 로고    scopus 로고
    • Comparative localization of cathepsin B protein and activity in colorectal cancer
    • Hazen LG, Bleeker FE, Lauritzen B, et al. Comparative localization of cathepsin B protein and activity in colorectal cancer. J Histochem Cytochem. 2000;48 (10): 1421-30.
    • (2000) J Histochem Cytochem , vol.48 , Issue.10 , pp. 1421-1430
    • Hazen, L.G.1    Bleeker, F.E.2    Lauritzen, B.3
  • 292
    • 33746149756 scopus 로고    scopus 로고
    • Acidic extracellular pH promotes experimental metastasis of human melanoma cells in athymic nude mice
    • Rofstad EK, Mathiesen B, Kindem K, Galappathi K. Acidic extracellular pH promotes experimental metastasis of human melanoma cells in athymic nude mice. Cancer Res. 2006;66 (13):6699-707.
    • (2006) Cancer Res , vol.66 , Issue.13 , pp. 6699-6707
    • Rofstad, E.K.1    Mathiesen, B.2    Kindem, K.3    Galappathi, K.4
  • 293
    • 50649084531 scopus 로고    scopus 로고
    • Loss of responsiveness to IGF-I in cells with reduced cathepsin L expression levels
    • Navab R, Pedraza C, Fallavollita L, et al. Loss of responsiveness to IGF-I in cells with reduced cathepsin L expression levels. Oncogene. 2008;27 (37):4973-85.
    • (2008) Oncogene , vol.27 , Issue.37 , pp. 4973-4985
    • Navab, R.1    Pedraza, C.2    Fallavollita, L.3
  • 294
    • 0036375964 scopus 로고    scopus 로고
    • Structure-based development of cathepsin L inhibitors and therapeutic applications for prevention of cancer metastasis and cancer-induced osteoporosis
    • Katunuma N, Tsuge H, Nukatsuka M, Fukushima M. Structure-based development of cathepsin L inhibitors and therapeutic applications for prevention of cancer metastasis and cancer-induced osteoporosis. Adv Enzyme Regul. 2002;42:159-72.
    • (2002) Adv Enzyme Regul , vol.42 , pp. 159-172
    • Katunuma, N.1    Tsuge, H.2    Nukatsuka, M.3    Fukushima, M.4
  • 295
    • 35448959223 scopus 로고    scopus 로고
    • A cathepsin K inhibitor reduces breast cancer induced osteolysis and skeletal tumor burden
    • Le Gall C, Bellahcene A, Bonnelye E, et al. A cathepsin K inhibitor reduces breast cancer induced osteolysis and skeletal tumor burden. Cancer Res. 2007;67 (20):9894-902.
    • (2007) Cancer Res , vol.67 , Issue.20 , pp. 9894-9902
    • Le Gall, C.1    Bellahcene, A.2    Bonnelye, E.3
  • 296
    • 79952278967 scopus 로고    scopus 로고
    • The cathepsin K inhibitor odanacatib suppresses bone resorption in women with breast cancer and established bone metastases: Results of a 4-week, double-blind, randomized, controlled trial
    • Jensen AB, Wynne C, Ramirez G, et al. The cathepsin K inhibitor odanacatib suppresses bone resorption in women with breast cancer and established bone metastases: results of a 4-week, double-blind, randomized, controlled trial. Clin Breast Cancer. 2010;10 (6):452-8.
    • (2010) Clin Breast Cancer , vol.10 , Issue.6 , pp. 452-458
    • Jensen, A.B.1    Wynne, C.2    Ramirez, G.3
  • 297
    • 77953510486 scopus 로고    scopus 로고
    • Odanacatib, a cathepsin-K inhibitor for osteoporosis: A two-year study in postmenopausal women with low bone density
    • Bone HG, McClung MR, Roux C, et al. Odanacatib, a cathepsin-K inhibitor for osteoporosis: a two-year study in postmenopausal women with low bone density. J Bone Miner Res. 2010;25 (5):937-47.
    • (2010) J Bone Miner Res , vol.25 , Issue.5 , pp. 937-947
    • Bone, H.G.1    McClung, M.R.2    Roux, C.3
  • 298
    • 20144388264 scopus 로고    scopus 로고
    • Modulation of the heparanase-inhibiting activity of heparin through selective desulfation, graded N-acetylation, and glycol splitting
    • Naggi A, Casu B, Perez M, et al. Modulation of the heparanase-inhibiting activity of heparin through selective desulfation, graded N-acetylation, and glycol splitting. J Biol Chem. 2005;280 (13):12103-13.
    • (2005) J Biol Chem , vol.280 , Issue.13 , pp. 12103-12113
    • Naggi, A.1    Casu, B.2    Perez, M.3
  • 299
    • 0034904048 scopus 로고    scopus 로고
    • Molecular properties and involvement of heparanase in cancer metastasis and angiogenesis
    • Vlodavsky I, Friedmann Y. Molecular properties and involvement of heparanase in cancer metastasis and angiogenesis. J Clin Invest. 2001;108 (3):341-7.
    • (2001) J Clin Invest , vol.108 , Issue.3 , pp. 341-347
    • Vlodavsky, I.1    Friedmann, Y.2
  • 300
    • 0033028789 scopus 로고    scopus 로고
    • Cloning of mammalian hepa-ranase, an important enzyme in tumor invasion and metastasis
    • Hulett MD, Freeman C, Hamdorf BJ, Baker RT, Harris MJ, Parish CR. Cloning of mammalian hepa-ranase, an important enzyme in tumor invasion and metastasis. Nat Med. 1999;5 (7):803-9.
    • (1999) Nat Med , vol.5 , Issue.7 , pp. 803-809
    • Hulett, M.D.1    Freeman, C.2    Hamdorf, B.J.3    Baker, R.T.4    Harris, M.J.5    Parish, C.R.6
  • 301
    • 0033810052 scopus 로고    scopus 로고
    • Expression of heparanase in normal, dysplastic, and neoplastic human colonic mucosa and stroma. Evidence for its role in colonic tumorigenesis
    • Friedmann Y, Vlodavsky I, Aingorn H, et al. Expression of heparanase in normal, dysplastic, and neoplastic human colonic mucosa and stroma. Evidence for its role in colonic tumorigenesis. Am J Pathol. 2000;157 (4):1167-75.
    • (2000) Am J Pathol , vol.157 , Issue.4 , pp. 1167-1175
    • Friedmann, Y.1    Vlodavsky, I.2    Aingorn, H.3
  • 302
    • 0033057962 scopus 로고    scopus 로고
    • Mammalian heparanase: Gene cloning, expression and function in tumor progression and metastasis
    • Vlodavsky I, Friedmann Y, Elkin M, et al. Mammalian heparanase: gene cloning, expression and function in tumor progression and metastasis. Nat Med. 1999;5 (7):793-802.
    • (1999) Nat Med , vol.5 , Issue.7 , pp. 793-802
    • Vlodavsky, I.1    Friedmann, Y.2    Elkin, M.3
  • 303
    • 0033565247 scopus 로고    scopus 로고
    • Identification of sulfated oligosaccharide-based inhibitors of tumor growth and metastasis using novel in vitro assays for angiogenesis and heparanase activity
    • Parish CR, Freeman C, Brown KJ, Francis DJ, Cowden WB. Identification of sulfated oligosaccharide-based inhibitors of tumor growth and metastasis using novel in vitro assays for angiogenesis and heparanase activity. Cancer Res. 1999;59 (14):3433-41.
    • (1999) Cancer Res , vol.59 , Issue.14 , pp. 3433-3441
    • Parish, C.R.1    Freeman, C.2    Brown, K.J.3    Francis, D.J.4    Cowden, W.B.5
  • 304
    • 33748683743 scopus 로고    scopus 로고
    • Regulation, function and clinical significance of heparanase in cancer metastasis and angiogenesis
    • Ilan N, Elkin M, Vlodavsky I. Regulation, function and clinical significance of heparanase in cancer metastasis and angiogenesis. Int J Biochem Cell Biol. 2006;38 (12):2018-39.
    • (2006) Int J Biochem Cell Biol , vol.38 , Issue.12 , pp. 2018-2039
    • Ilan, N.1    Elkin, M.2    Vlodavsky, I.3
  • 305
    • 77953974391 scopus 로고    scopus 로고
    • Multicentre phase I/II study of PI-88, a heparanase inhibitor in combination with docetaxel in patients with metastatic castrate-resistant prostate cancer
    • Khasraw M, Pavlakis N, McCowatt S, et al. Multicentre phase I/II study of PI-88, a heparanase inhibitor in combination with docetaxel in patients with metastatic castrate-resistant prostate cancer. Ann Oncol. 2010;21 (6):1302-7.
    • (2010) Ann Oncol , vol.21 , Issue.6 , pp. 1302-1307
    • Khasraw, M.1    Pavlakis, N.2    McCowatt, S.3
  • 306
    • 84984569951 scopus 로고    scopus 로고
    • Heparanase inhibitor PI-88 as adjuvant therapy for hepatocellular carcinoma after curative resection: A randomized phase II trial for safety and optimal dosage
    • Liu CJ, Lee PH, Lin DY, et al. Heparanase inhibitor PI-88 as adjuvant therapy for hepatocellular carcinoma after curative resection: a randomized phase II trial for safety and optimal dosage. J Hepatol. 2009;50 (5):958-68.
    • (2009) J Hepatol , vol.50 , Issue.5 , pp. 958-968
    • Liu, C.J.1    Lee, P.H.2    Lin, D.Y.3
  • 307
    • 0027977941 scopus 로고
    • Paracrine growth stimulation by hepatocyte-derived insulin-like growth factor-1: A regulatory mechanism for carcinoma cells metastatic to the liver
    • Long L, Nip J, Brodt P. Paracrine growth stimulation by hepatocyte-derived insulin-like growth factor-1: a regulatory mechanism for carcinoma cells metastatic to the liver. Cancer Res. 1994;54 (14):3732-7.
    • (1994) Cancer Res , vol.54 , Issue.14 , pp. 3732-3737
    • Long, L.1    Nip, J.2    Brodt, P.3
  • 308
    • 0002460807 scopus 로고    scopus 로고
    • Tumor dormancy induced by downregulation of urokinase receptor in human carcinoma involves integrin and MAPK signaling
    • Aguirre Ghiso JA, Kovalski K, Ossowski L. Tumor dormancy induced by downregulation of urokinase receptor in human carcinoma involves integrin and MAPK signaling. J Cell Biol. 1999;147 (1):89-104.
    • (1999) J Cell Biol , vol.147 , Issue.1 , pp. 89-104
    • Aguirre Ghiso, J.A.1    Kovalski, K.2    Ossowski, L.3
  • 309
    • 33645990004 scopus 로고    scopus 로고
    • Suppression of EGF-R signaling reduces the incidence of prostate cancer metastasis in nude mice
    • Angelucci A, Gravina GL, Rucci N, et al. Suppression of EGF-R signaling reduces the incidence of prostate cancer metastasis in nude mice. Endocr Relat Cancer. 2006;13 (1):197-210.
    • (2006) Endocr Relat Cancer , vol.13 , Issue.1 , pp. 197-210
    • Angelucci, A.1    Gravina, G.L.2    Rucci, N.3
  • 310
    • 0028885643 scopus 로고
    • Individual development and uPA-receptor expression of disseminated tumour cells in bone marrow: A reference to early systemic disease in solid cancer
    • Heiss MM, Allgayer H, Gruetzner KU, et al. Individual development and uPA-receptor expression of disseminated tumour cells in bone marrow: a reference to early systemic disease in solid cancer. Nat Med. 1995;1 (10):1035-9.
    • (1995) Nat Med , vol.1 , Issue.10 , pp. 1035-1039
    • Heiss, M.M.1    Allgayer, H.2    Gruetzner, K.U.3
  • 311
    • 77950594400 scopus 로고    scopus 로고
    • Extracellular matrix: A gatekeeper in the transition from dormancy to metastatic growth
    • Barkan D, Green JE, Chambers AF. Extracellular matrix: a gatekeeper in the transition from dormancy to metastatic growth. Eur J Cancer. 2010;46 (7): 1181-8.
    • (2010) Eur J Cancer , vol.46 , Issue.7 , pp. 1181-1188
    • Barkan, D.1    Green, J.E.2    Chambers, A.F.3
  • 312
    • 0036097996 scopus 로고    scopus 로고
    • Prognostic significance of fibrotic focus in invasive ductal carcinoma of the breast: A prospective observational study
    • Hasebe T, Sasaki S, Imoto S, Mukai K, Yokose T, Ochiai A. Prognostic significance of fibrotic focus in invasive ductal carcinoma of the breast: a prospective observational study. Mod Pathol. 2002;15 (5):502-16.
    • (2002) Mod Pathol , vol.15 , Issue.5 , pp. 502-516
    • Hasebe, T.1    Sasaki, S.2    Imoto, S.3    Mukai, K.4    Yokose, T.5    Ochiai, A.6
  • 313
    • 0035671826 scopus 로고    scopus 로고
    • Elevated serum bone sialoprotein and osteopontin in colon, breast, prostate, and lung cancer
    • Fedarko NS, Jain A, Karadag A, Van Eman MR, Fisher LW. Elevated serum bone sialoprotein and osteopontin in colon, breast, prostate, and lung cancer. Clin Cancer Res. 2001;7 (12):4060-6.
    • (2001) Clin Cancer Res , vol.7 , Issue.12 , pp. 4060-4066
    • Fedarko, N.S.1    Jain, A.2    Karadag, A.3    Van Eman, M.R.4    Fisher, L.W.5
  • 314
    • 39749187284 scopus 로고    scopus 로고
    • Small integrin-binding ligand N-linked glycoproteins (SIBLINGs): Multifunctional proteins in cancer
    • Bellahcene A, Castronovo V, Ogbureke KU, Fisher LW, Fedarko NS. Small integrin-binding ligand N-linked glycoproteins (SIBLINGs): multifunctional proteins in cancer. Nat Rev Cancer. 2008;8 (3):212-26.
    • (2008) Nat Rev Cancer , vol.8 , Issue.3 , pp. 212-226
    • Bellahcene, A.1    Castronovo, V.2    Ogbureke, K.U.3    Fisher, L.W.4    Fedarko, N.S.5
  • 315
    • 0037391756 scopus 로고    scopus 로고
    • Predicting hepatitis B virus-positive metastatic hepatocellular carcinomas using gene expression profiling and supervised machine learning
    • Ye QH, Qin LX, Forgues M, et al. Predicting hepatitis B virus-positive metastatic hepatocellular carcinomas using gene expression profiling and supervised machine learning. Nat Med. 2003;9 (4):416-23.
    • (2003) Nat Med , vol.9 , Issue.4 , pp. 416-423
    • Ye, Q.H.1    Qin, L.X.2    Forgues, M.3
  • 317
    • 33845720585 scopus 로고    scopus 로고
    • Differential expression of matrix metalloproteinases in brain- and bone-seeking clones of metastatic MDA-MB-231 breast cancer cells
    • Stark AM, Anuszkiewicz B, Mentlein R, Yoneda T, Mehdorn HM, Held-Feindt J. Differential expression of matrix metalloproteinases in brain- and bone-seeking clones of metastatic MDA-MB-231 breast cancer cells. J Neurooncol. 2007;81 (1): 39-48.
    • (2007) J Neurooncol , vol.81 , Issue.1 , pp. 39-48
    • Stark, A.M.1    Anuszkiewicz, B.2    Mentlein, R.3    Yoneda, T.4    Mehdorn, H.M.5    Held-feindt, J.6
  • 319
    • 0023037767 scopus 로고
    • Growth factors in bone matrix. Isolation of multiple types by affinity chromatography on heparin-Sepharose
    • Hauschka PV, Mavrakos AE, Iafrati MD, Doleman SE, Klagsbrun M. Growth factors in bone matrix. Isolation of multiple types by affinity chromatography on heparin-Sepharose. J Biol Chem. 1986;261 (27):12665-74.
    • (1986) J Biol Chem , vol.261 , Issue.27 , pp. 12665-12674
    • Hauschka, P.V.1    Mavrakos, A.E.2    Iafrati, M.D.3    Doleman, S.E.4    Klagsbrun, M.5
  • 320
    • 5144229126 scopus 로고    scopus 로고
    • Breast cancer cells induce osteoblast apoptosis: A possible contributor to bone degradation
    • Mastro AM, Gay CV, Welch DR, et al. Breast cancer cells induce osteoblast apoptosis: a possible contributor to bone degradation. J Cell Biochem. 2004;91 (2):265-76.
    • (2004) J Cell Biochem , vol.91 , Issue.2 , pp. 265-276
    • Mastro, A.M.1    Gay, C.V.2    Welch, D.R.3
  • 321
    • 0036792257 scopus 로고    scopus 로고
    • Expression of interleukin 8 and not parathyroid hormone-related protein by human breast cancer cells correlates with bone metastasis in vivo
    • Bendre MS, Gaddy-Kurten D, Mon-Foote T, et al. Expression of interleukin 8 and not parathyroid hormone-related protein by human breast cancer cells correlates with bone metastasis in vivo. Cancer Res. 2002;62 (19):5571-9.
    • (2002) Cancer Res , vol.62 , Issue.19 , pp. 5571-5579
    • Bendre, M.S.1    Gaddy-kurten, D.2    Mon-foote, T.3
  • 322
    • 0035452412 scopus 로고    scopus 로고
    • Increased cyclooxygenase-2 (cox-2) expression and activity in a murine model of metastatic breast cancer
    • Kundu N, Yang Q, Dorsey R, Fulton AM. Increased cyclooxygenase-2 (cox-2) expression and activity in a murine model of metastatic breast cancer. Int J Cancer. 2001;93 (5):681-6.
    • (2001) Int J Cancer , vol.93 , Issue.5 , pp. 681-686
    • Kundu, N.1    Yang, Q.2    Dorsey, R.3    Fulton, A.M.4
  • 323
    • 35948935128 scopus 로고    scopus 로고
    • Involvement of alpha(v)beta3 integrins in osteoclast function
    • Nakamura I, le Duong T, Rodan SB, Rodan GA. Involvement of alpha(v)beta3 integrins in osteoclast function. J Bone Miner Metab. 2007;25 (6):337-44.
    • (2007) J Bone Miner Metab , vol.25 , Issue.6 , pp. 337-344
    • Nakamura, I.1    le Duong, T.2    Rodan, S.B.3    Rodan, G.A.4
  • 324
    • 48349128061 scopus 로고    scopus 로고
    • Bone resorption increases tumour growth in a mouse model of osteosclerotic breast cancer metastasis
    • Zheng Y, Zhou H, Fong-Yee C, Modzelewski JR, Seibel MJ, Dunstan CR. Bone resorption increases tumour growth in a mouse model of osteosclerotic breast cancer metastasis. Clin Exp Metastasis. 2008;25 (5):559-67.
    • (2008) Clin Exp Metastasis , vol.25 , Issue.5 , pp. 559-567
    • Zheng, Y.1    Zhou, H.2    Fong-yee, C.3    Modzelewski, J.R.4    Seibel, M.J.5    Dunstan, C.R.6
  • 325
    • 0029085123 scopus 로고
    • Identification of endothelin-1 in the pathophysiology of metastatic adenocarcinoma of the prostate
    • Nelson JB, Hedican SP, George DJ, et al. Identification of endothelin-1 in the pathophysiology of metastatic adenocarcinoma of the prostate. Nat Med. 1995;1 (9):944-9.
    • (1995) Nat Med , vol.1 , Issue.9 , pp. 944-949
    • Nelson, J.B.1    Hedican, S.P.2    George, D.J.3
  • 326
    • 35648968713 scopus 로고    scopus 로고
    • A phase 3 randomized controlled trial of the efficacy and safety of atrasentan in men with metastatic hormone-refractory prostate cancer
    • Carducci MA, Saad F, Abrahamsson PA, et al. A phase 3 randomized controlled trial of the efficacy and safety of atrasentan in men with metastatic hormone-refractory prostate cancer. Cancer. 2007;110 (9): 1959-66.
    • (2007) Cancer , vol.110 , Issue.9 , pp. 1959-1966
    • Carducci, M.A.1    Saad, F.2    Abrahamsson, P.A.3
  • 327
    • 79151468942 scopus 로고    scopus 로고
    • A phase I study of zibotentan (ZD4054) in patients with metastatic, castrate-resistant prostate cancer
    • Schelman WR, Liu G, Wilding G, Morris T, Phung D, Dreicer R. A phase I study of zibotentan (ZD4054) in patients with metastatic, castrate-resistant prostate cancer. Invest New Drugs. 2011;29 (1):118-25.
    • (2011) Invest New Drugs , vol.29 , Issue.1 , pp. 118-125
    • Schelman, W.R.1    Liu, G.2    Wilding, G.3    Morris, T.4    Phung, D.5    Dreicer, R.6
  • 328
    • 75049083784 scopus 로고    scopus 로고
    • Increased skeletal VEGF enhances beta-catenin activity and results in excessively ossified bones
    • Maes C, Goossens S, Bartunkova S, et al. Increased skeletal VEGF enhances beta-catenin activity and results in excessively ossified bones. EMBO J. 2010;29 (2):424-41.
    • (2010) EMBO J , vol.29 , Issue.2 , pp. 424-441
    • Maes, C.1    Goossens, S.2    Bartunkova, S.3
  • 329
    • 0033153362 scopus 로고    scopus 로고
    • Osteomimetic properties of prostate cancer cells: A hypothesis supporting the predilection of prostate cancer metastasis and growth in the bone environment
    • Koeneman KS, Yeung F, Chung LW. Osteomimetic properties of prostate cancer cells: a hypothesis supporting the predilection of prostate cancer metastasis and growth in the bone environment. Prostate. 1999;39 (4):246-61.
    • (1999) Prostate , vol.39 , Issue.4 , pp. 246-261
    • Koeneman, K.S.1    Yeung, F.2    Chung, L.W.3
  • 330
    • 0036005977 scopus 로고    scopus 로고
    • Osteopontin modulates prostate carcinoma invasive capacity through RGD-dependent upregulation of plasminogen activators
    • Angelucci A, Festuccia C, D'Andrea G, Teti A, Bologna M. Osteopontin modulates prostate carcinoma invasive capacity through RGD-dependent upregulation of plasminogen activators. Biol Chem. 2002;383 (1):229-34.
    • (2002) Biol Chem , vol.383 , Issue.1 , pp. 229-234
    • Angelucci, A.1    Festuccia, C.2    D'Andrea, G.3    Teti, A.4    Bologna, M.5
  • 331
    • 0033199111 scopus 로고    scopus 로고
    • Osteonectin promotes prostate cancer cell migration and invasion: A possible mechanism for metastasis to bone
    • Jacob K, Webber M, Benayahu D, Kleinman HK. Osteonectin promotes prostate cancer cell migration and invasion: a possible mechanism for metastasis to bone. Cancer Res. 1999;59 (17):4453-7.
    • (1999) Cancer Res , vol.59 , Issue.17 , pp. 4453-4457
    • Jacob, K.1    Webber, M.2    Benayahu, D.3    Kleinman, H.K.4
  • 332
    • 35648970587 scopus 로고    scopus 로고
    • Osteopontin overexpression in breast cancer: Knowledge gained and possible implications for clinical management
    • Tuck AB, Chambers AF, Allan AL. Osteopontin overexpression in breast cancer: knowledge gained and possible implications for clinical management. J Cell Biochem. 2007;102 (4):859-68.
    • (2007) J Cell Biochem , vol.102 , Issue.4 , pp. 859-868
    • Tuck, A.B.1    Chambers, A.F.2    Allan, A.L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.