Regulation of MMP-1 and MMP-2 production through CD147/extracellular matrix metalloproteinase inducer interactions

Cancer Research

Volumn 61, Issue 5, 2001, Pages 2276-2281

  Sun, J ^a   Hemler, M E ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD147 ANTIGEN; ENZYME INDUCING AGENT; GELATINASE A; GLYCOSYLATED PROTEIN; HYBRID PROTEIN; INTERSTITIAL COLLAGENASE; MATRIGEL; UNCLASSIFIED DRUG;

ARTICLE; BASEMENT MEMBRANE; BREAST CANCER; CANCER CELL CULTURE; CANCER INVASION; CELL INTERACTION; CONTROLLED STUDY; DEGLYCOSYLATION; ENZYME RELEASE; ENZYME SYNTHESIS; HUMAN; HUMAN CELL; METASTASIS; PRIORITY JOURNAL; SKIN FIBROBLAST;

ANIMALS; ANTIGENS, CD; ANTIGENS, CD147; ANTIGENS, NEOPLASM; ANTIGENS, SURFACE; AVIAN PROTEINS; BLOOD PROTEINS; CELL ADHESION; COS CELLS; CRICETINAE; FIBROSARCOMA; GLYCOSYLATION; HUMANS; MATRIX METALLOPROTEINASE 1; MATRIX METALLOPROTEINASE 2; MEMBRANE GLYCOPROTEINS; NEOPLASM INVASIVENESS; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT FUSION PROTEINS; TUMOR CELLS, CULTURED;

EID: 0035266353     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (36)

1. Tumor cell interactions with the extracellular matrix during invasion and metastasis
2. ECM and cell surface proteolysis: Regulating cellular ecology
3. r 72,000 and 92,000 type IV collagenases in human skin cancers by in situ hybridization
4. Interstitial collagenase gene expression in oral squamous cell carcinoma
5. Stromal expression of 72 kDa type IV collagenase (MMP-2) and TIMP-2 mRNAs in colorectal neoplasia
6. Production of matrix metalloproteinases 2 and 3 (stromelysin) by stromal cells of giant cell tumor of bone
7. Contributions of tumor and stromal matrix metalloproteinases to tumor progression, invasion and metastasis
8. Monoclonal antibody preparation and purification of a tumor cell collagenase-stimulatory factor
9. Tumor cell-derived collagenase-stimulatory factor increases expression of interstitial collagenase, stromelysin, and 72-kDa gelatinase
10. The human tumor cell-derived collagenase stimulatory factor (renamed EMMPRIN) is a member of the immunoglobulin superfamily
11. Basigin, a new, broadly distributed member of the immunoglobulin superfamily, has strong homology with both the immunoglobulin V domain and the β-chain of major histocompatibility complex class II antigen
12. The MRC OX-47 antigen is a member of the immunoglobulin superfamily with an unusual transmembrane sequence
13. Neurothelin: Amino acid sequence, cell surface dynamics and actin colocalization
14. Human leukocyte activation antigen M6, a member of the Ig superfamily, is the species homologue of rat OX-47, mouse basigin, and chicken HT7 molecule
15. The inducible blood-brain barrier specific molecule HT7 is a novel immunoglobulin-like cell surface glycoprotein
16. A null mutation in basigin, an immunoglobulin superfamily member, indicates its important roles in peri-implantation development and spermatogenesis
17. Female sterility in mice lacking the basigin gene, which encodes a transmembrane glycoprotein belonging to the immunoglobulin superfamily
18. Roles of basigin, a member of the immunoglobulin superfamily, in behavior as to an irritating odor, lymphocyte response, and blood-brain barrier
19. Enhanced expression of a tumor-cell-derived collagenase-stimulatory factor in urothelial carcinoma: Its usefulness as a tumor marker for bladder cancers
20. Tumor collagenase stimulatory factor (TCSF) expression and localization in human lung and breast cancers
21. Expression of gelatinase B and the extracellular matrix metalloproteinase inducer EMMPRIN in benign and malignant pigment cell lesions of the skin
22. Expression of emmprin by oral squamous cell carcinoma
23. Stimulation of matrix metalloproteinase production by recombinant extracellular matrix metalloproteinase inducer from transfected Chinese hamster ovary cells
24. Generation of monoclonal antibodies to integrin-associated proteins: Evidence that α3β1 complexes with EMMPRIN/basigin/OX47/M6
25. Expression and functional characterization of a soluble form of vascular cell adhesion molecule 1 (VCAM1)
26. Comparison of mouse immunoglobulin γ 2a and γ 2b chain genes suggests that exons can be exchanged between genes in a multigenic family
27. Tumor and stromal expression of matrix metalloproteinases and their role in tumor progression
28. Identification of a peptide sequence involved in homophilic binding in the neural cell adhesion molecule NCAM
29. Homophilic adhesion between Ig superfamily carcinoembryonic antigen molecules involves double reciprocal bonds
30. Anti-α3 integrin antibody induces the activated form of matrix metalloprotease-2 (MMP-2) with concomitant stimulation of invasion through Matrigel by human rhabdomyosarcoma cells
31. Introduction of basic fibroblast growth factor gene into mouse renal cell carcinoma cell line enhances its metastatic potential
32. T cell activation-associated epitopes of CD147 in regulation of the T cell response, and their definition by antibody affinity and antigen density
33. Tumor-derived EMMPRIN (extracellular matrix metalloproteinase inducer) stimulates collagenase transcription through MAPK p38
34. Tumor targeting with a selective gelatinase inhibitor
35. Suppression of the tumorigenic and metastatic abilities of murine B16-F10 melanoma cells in vivo by the overexpression of the tissue inhibitor of the metalloproteinases-I
36. Control of lymphatic and hematogenous metastasis of a rat mammary carcinoma by the matrix metalloproteinase inhibitor batimastat (BB-94)