Cimetidine inhibits cancer cell adhesion to endothelial cells and prevents metastasis by blocking E-selectin expression

Cancer Research

Volumn 60, Issue 14, 2000, Pages 3978-3984

  Kobayashi, Ken Ichi ^a,b   Matsumoto, Sumio ^b   Morishima, Takashi ^a,b   Kawabe, Takumi ^a   Okamoto, Takashi ^a  

^a NAGOYA CITY UNIV MEDICAL SCHOOL   (Japan)

^b FUJITA HEALTH UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CIMETIDINE; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; FAMOTIDINE; HISTAMINE RECEPTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIGAND; MESSENGER RNA; RANITIDINE; SIALIC ACID DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD GROUP LEWIS SYSTEM; CELL ADHESION; CELL SURFACE; COLORECTAL CANCER; DRUG EFFECT; ENDOTHELIUM CELL; FEMALE; GENE EXPRESSION; HUMAN; HUMAN CELL; METASTASIS; METASTASIS INHIBITION; MOUSE; NONHUMAN; NUDE MOUSE; PRIORITY JOURNAL; PROTEIN EXPRESSION; TUMOR CELL LINE;

ANIMALS; CELL ADHESION; CELL NUCLEUS; CIMETIDINE; COLORECTAL NEOPLASMS; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; E-SELECTIN; ENDOTHELIUM, VASCULAR; ENZYME INHIBITORS; ENZYME-LINKED IMMUNOSORBENT ASSAY; FAMOTIDINE; HISTAMINE H2 ANTAGONISTS; HUMANS; INTERLEUKIN-1; LIVER NEOPLASMS; MICE; MICE, NUDE; MICROSCOPY, CONFOCAL; NEOPLASM TRANSPLANTATION; NF-KAPPA B; OLIGOSACCHARIDES; RANITIDINE; RNA, MESSENGER; TRANS-ACTIVATION (GENETICS); TUMOR CELLS, CULTURED; UMBILICAL VEINS;

EID: 0034660854     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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