Suppression of integrin αυβ6 by RNA interference in colon cancer cells inhibits extracellular matrix degradation through the MAPK pathway

International Journal of Cancer

Volumn 123, Issue 6, 2008, Pages 1311-1317

  Wang, Jiayong ^a   Zhang, Zhaoyang ^a   Xu, Kesen ^a   Sun, Xiaohui ^a   Yang, Guangyun ^a   Niu, Weibo ^a   Liu, Enyu ^a   Peng, Cheng ^a   Lin, Pengfei ^a   Wang, Jian ^a   Chen, Rong ^b   Agrez, Michael ^c   Niu, Jun ^a  

^a SHANDONG UNIVERSITY   (China)

^b SHANDONG UNIVERSITY   (China)

^c HUNTER MEDICAL RESEARCH INSTITUTE   (Australia)

Author keywords

Colon cancer; Integrin 6; MAP kinase; RNA interference

Indexed keywords

ALPHAVBETA6 INTEGRIN; COLLAGEN TYPE 4; GELATINASE A; GELATINASE B; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PLASMID VECTOR; PLASMINOGEN; RNA; SHORT HAIRPIN RNA; INTEGRIN; INTEGRIN ALPHAUPSILONBETA6; SMALL INTERFERING RNA; UROKINASE;

ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; COLLAGEN DEGRADATION; COLON CARCINOMA; DOWN REGULATION; EXTRACELLULAR MATRIX; HUMAN; HUMAN CELL; PLASMINOGEN ACTIVATION; PRIORITY JOURNAL; PROGNOSIS; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN SYNTHESIS INHIBITION; RNA INTERFERENCE; CANCER INVASION; COLON TUMOR; DRUG ANTAGONISM; GENETIC TRANSFECTION; GENETICS; METABOLISM; PATHOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TUMOR CELL LINE; WESTERN BLOTTING;

BLOTTING, WESTERN; CELL LINE, TUMOR; COLONIC NEOPLASMS; EXTRACELLULAR MATRIX; HUMANS; INTEGRINS; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; MITOGEN-ACTIVATED PROTEIN KINASES; NEOPLASM INVASIVENESS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA INTERFERENCE; RNA, MESSENGER; RNA, SMALL INTERFERING; TRANSFECTION; URINARY PLASMINOGEN ACTIVATOR;

EID: 49749092745     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.23656     Document Type: Article

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