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Volumn 22, Issue 1, 2005, Pages 69-76

Selective antimetastatic effect of heparins in preclinical human melanoma models is based on inhibition of migration and microvascular arrest

Author keywords

Cell migration; Human melanoma xenograft; Low molecular weight heparin (LMWH); Metastasis; Unfractionated heparin (UFH)

Indexed keywords

DALTEPARIN; HEPARIN; HEPARIN DERIVATIVE; LEPIRUDIN; LOW MOLECULAR WEIGHT HEPARIN; RECOMBINANT HIRUDIN;

EID: 23944442968     PISSN: 02620898     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10585-005-3859-6     Document Type: Article
Times cited : (37)

References (39)
  • 2
    • 0033396058 scopus 로고    scopus 로고
    • Cancer. Coagulation and anticoagulation
    • A Letai DJ. Kuter 1999 Cancer. Coagulation and anticoagulation Oncologist 4 443 9
    • (1999) Oncologist , vol.4 , pp. 443-9
    • Letai, A.1    Kuter, D.J.2
  • 3
    • 0026762705 scopus 로고
    • Lower mortality in cancer patients treated with low-molecular-weight versus standard heparin
    • D Green RD Hull R Brant 1992 Lower mortality in cancer patients treated with low-molecular-weight versus standard heparin Lancet 339(8807) 1476
    • (1992) Lancet , vol.339 , Issue.8807 , pp. 1476
    • Green, D.1    Hull, R.D.2    Brant, R.3
  • 4
    • 0037775584 scopus 로고    scopus 로고
    • Low-molecular-weight heparin versus a coumarin for the prevention of recurrent venous thromboembolism in patients with cancer
    • AYY Lee MN Levine RI Baker 2003 Low-molecular-weight heparin versus a coumarin for the prevention of recurrent venous thromboembolism in patients with cancer N Engl J Med 349 146 53
    • (2003) N Engl J Med , vol.349 , pp. 146-53
    • Lee, A.Y.Y.1    Levine, M.N.2    Baker, R.I.3
  • 5
    • 0019523102 scopus 로고
    • Effect of warfarin on survival in small cell carcinoma of the lung
    • LR Zacharski WG Henderson FR Rickles 1981 Effect of warfarin on survival in small cell carcinoma of the lung JAMA 145 831 5
    • (1981) JAMA , vol.145 , pp. 831-5
    • Zacharski, L.R.1    Henderson, W.G.2    Rickles, F.R.3
  • 6
    • 0021243907 scopus 로고
    • Effect of warfarin anticoagulation on survival in carcinoma of the lung, colon, head and neck, and prostate
    • LP Zacharski WG Henderson FR Rickles 1984 Effect of warfarin anticoagulation on survival in carcinoma of the lung, colon, head and neck, and prostate Cancer 53 2046 52
    • (1984) Cancer , vol.53 , pp. 2046-52
    • Zacharski, L.P.1    Henderson, W.G.2    Rickles, F.R.3
  • 7
    • 0024311763 scopus 로고
    • A randomized trial of anticoagulation with warfarin and of alternating chemotherapy in extensive small-cell lung cancer by the cancer and leukemia group B
    • AP Chahinian KJ Propert JH Ware 1989 A randomized trial of anticoagulation with warfarin and of alternating chemotherapy in extensive small-cell lung cancer by the cancer and leukemia group B J Clin Oncol 7 993 1002
    • (1989) J Clin Oncol , vol.7 , pp. 993-1002
    • Chahinian, A.P.1    Propert, K.J.2    Ware, J.H.3
  • 8
    • 0028239146 scopus 로고
    • Subcutanous heparin treatment increases survival in small cell lung cancer
    • B Lebeau C Chastang J-M Brechot 1994 Subcutanous heparin treatment increases survival in small cell lung cancer Cancer 74 38 45
    • (1994) Cancer , vol.74 , pp. 38-45
    • Lebeau, B.1    Chastang, C.2    Brechot, J.-M.3
  • 9
    • 0034164514 scopus 로고    scopus 로고
    • Effect of low molecular weight heparin (Certoparin) versus unfractionated heparin on cancer survival following breast and pelvic cancer surgery: A prospective randomized double-blind trial
    • GF von Tempelhoff J Harenberg F Niemann 2000 Effect of low molecular weight heparin (Certoparin) versus unfractionated heparin on cancer survival following breast and pelvic cancer surgery: A prospective randomized double-blind trial Int J Oncol 16 815 24
    • (2000) Int J Oncol , vol.16 , pp. 815-24
    • Von Tempelhoff, G.F.1    Harenberg, J.2    Niemann, F.3
  • 10
    • 0034874857 scopus 로고    scopus 로고
    • Safety of perioperative minidose heparin in patients undergoing brain tumor surgery: A prospective, randomized double-blind study
    • S Constantini A Kanner A Friedmann 2001 Safety of perioperative minidose heparin in patients undergoing brain tumor surgery: a prospective, randomized double-blind study J Neurosurg 94 918 21
    • (2001) J Neurosurg , vol.94 , pp. 918-21
    • Constantini, S.1    Kanner, A.2    Friedmann, A.3
  • 11
    • 0142011052 scopus 로고    scopus 로고
    • Phase II study of docetaxel plus enoxaparin in chemotherapy naïve patients with metastatic non-small cell lung cancer: Preliminary results
    • F Robert E Busby MB Marques 2003 Phase II study of docetaxel plus enoxaparin in chemotherapy naïve patients with metastatic non-small cell lung cancer: Preliminary results Lung Cancer 42 237 45
    • (2003) Lung Cancer , vol.42 , pp. 237-45
    • Robert, F.1    Busby, E.2    Marques, M.B.3
  • 12
    • 0035109328 scopus 로고    scopus 로고
    • The complex effects of heparins on cancer progression and metastasis in experimental studies
    • SS Smorenburg CJF. van Noorden 2001 The complex effects of heparins on cancer progression and metastasis in experimental studies Pharmacol Rev 59 93 105
    • (2001) Pharmacol Rev , vol.59 , pp. 93-105
    • Smorenburg, S.S.1    Van Noorden, C.J.F.2
  • 13
    • 0035853111 scopus 로고    scopus 로고
    • Heparin and cancer revisited: Mechanistic connections involving platelets, P-selectin, carcinoma mucins, and tumor metastasis
    • L Borsig R Wong J Feramisco 2001 Heparin and cancer revisited: mechanistic connections involving platelets, P-selectin, carcinoma mucins, and tumor metastasis Proc Natl Acad Sci USA 98 3352 7
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 3352-7
    • Borsig, L.1    Wong, R.2    Feramisco, J.3
  • 14
    • 0037133173 scopus 로고    scopus 로고
    • Synergistic effects of L- and P-selectin in facilitating tumor metastasis can involve non-mucin ligands and implicate leukocytes as enhancers of metastasis
    • L Borsig R Wong RO Hynes 2002 Synergistic effects of L- and P-selectin in facilitating tumor metastasis can involve non-mucin ligands and implicate leukocytes as enhancers of metastasis Proc Natl Acad Sci USA 99 2193 8
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 2193-8
    • Borsig, L.1    Wong, R.2    Hynes, R.O.3
  • 15
    • 16544390675 scopus 로고    scopus 로고
    • Endothelial P-selectin as a target of heparin action in experimental melanoma lung metastasis
    • RJ Ludwing B Bochme M Podda 2004 Endothelial P-selectin as a target of heparin action in experimental melanoma lung metastasis Cancer Res 64 2743 50
    • (2004) Cancer Res , vol.64 , pp. 2743-50
    • Ludwing, R.J.1    Bochme, B.2    Podda, M.3
  • 16
    • 0027354344 scopus 로고
    • Comparison of 5 microplate colorimetric assays for in vitrocytotoxicity testing and cell proliferation assays
    • M Martin M. Clynes 1993 Comparison of 5 microplate colorimetric assays for in vitrocytotoxicity testing and cell proliferation assays Cytotechnology 11 49 58
    • (1993) Cytotechnology , vol.11 , pp. 49-58
    • Martin, M.1    Clynes, M.2
  • 17
    • 1942536196 scopus 로고    scopus 로고
    • A WT1 expressing metastatic human Kaposi sarcoma xenograft model
    • E Rásó L Mészáros A Albini 2004 A WT1 expressing metastatic human Kaposi sarcoma xenograft model Pathol Oncol Res 10 22 5
    • (2004) Pathol Oncol Res , vol.10 , pp. 22-5
    • Rásó, E.1    Mészáros, L.2    Albini, A.3
  • 18
    • 0003377172 scopus 로고    scopus 로고
    • Guidelines for the Welfare of Animals in Experimental Neoplasia
    • (Second Edition)
    • United Kingdom Co-ordinating Committee on Cancer Research (UKCCCR). Guidelines for the Welfare of Animals in Experimental Neoplasia (Second Edition). Br J Cancer 1998; 77: 1-10.
    • (1998) Br J Cancer , vol.77 , pp. 1-10
  • 19
    • 1842463681 scopus 로고    scopus 로고
    • Antimetastatic effect of tinzaparin, a low-molecular-weight heparin
    • A Amirkoshravi SA Mousa M Amaya 2003 Antimetastatic effect of tinzaparin, a low-molecular-weight heparin J Thromb Haemost 1 1972 6
    • (2003) J Thromb Haemost , vol.1 , pp. 1972-6
    • Amirkoshravi, A.1    Mousa, S.A.2    Amaya, M.3
  • 20
    • 0026029064 scopus 로고
    • Thrombin stimulates tumor-platelet adhesion in vitro and metastasis in vivo
    • ML Nierodzik A Plotkin F Kajumo S. Karpatkin 1991 Thrombin stimulates tumor-platelet adhesion in vitro and metastasis in vivo J Clin Invest 87 229 36
    • (1991) J Clin Invest , vol.87 , pp. 229-36
    • Nierodzik, M.L.1    Plotkin, A.2    Kajumo, F.3    Karpatkin, S.4
  • 21
    • 0025938196 scopus 로고
    • Inhibition of murine melanoma experimental metastasis by recombinant desulfatohirudin, a highly specific thrombin inhibitor
    • N Esumi D Fan IJ. Fidler 1991 Inhibition of murine melanoma experimental metastasis by recombinant desulfatohirudin, a highly specific thrombin inhibitor Cancer Res 51 4549 56
    • (1991) Cancer Res , vol.51 , pp. 4549-56
    • Esumi, N.1    Fan, D.2    Fidler, I.J.3
  • 22
    • 1342325343 scopus 로고    scopus 로고
    • Persistent signaling by dysregulated thrombin receptor trafficking promotes breast carcinoma cell invasion
    • MA Booden LB Eckert CJ Der J. Trejo 2004 Persistent signaling by dysregulated thrombin receptor trafficking promotes breast carcinoma cell invasion Mol Cell Biol 24 1990 9
    • (2004) Mol Cell Biol , vol.24 , pp. 1990-9
    • Booden, M.A.1    Eckert, L.B.2    Der, C.J.3    Trejo, J.4
  • 23
    • 0037406817 scopus 로고    scopus 로고
    • Aberrant expression and activation of the thrombin receptor protease-activated receptor-1 induces cell proliferation and motility in human colon cancer cells
    • D Darmoul V Gratiuo H Devaud 2003 Aberrant expression and activation of the thrombin receptor protease-activated receptor-1 induces cell proliferation and motility in human colon cancer cells Am J Pathol 162 1503 13
    • (2003) Am J Pathol , vol.162 , pp. 1503-13
    • Darmoul, D.1    Gratiuo, V.2    Devaud, H.3
  • 24
    • 0345306669 scopus 로고    scopus 로고
    • Loss activator protein-2alpha results in overexpression of protease-activated receptor-1 and correlates with the malignant phenotype of human melanoma
    • C Tellez M McCarty M Ruiz H. Bar-Eli 2003 Loss activator protein-2alpha results in overexpression of protease-activated receptor-1 and correlates with the malignant phenotype of human melanoma J Biol Chem 178 46632 42
    • (2003) J Biol Chem , vol.178 , pp. 46632-42
    • Tellez, C.1    McCarty, M.2    Ruiz, M.3    Bar-Eli, H.4
  • 26
    • 0032519957 scopus 로고    scopus 로고
    • Differential interactions of heparin and heparan sulfate glycosaminoglycans with the selectins
    • A Koenig K Norgard-Sumnicht R Linhardt 1998 Differential interactions of heparin and heparan sulfate glycosaminoglycans with the selectins J Clin Invest 101 877 89
    • (1998) J Clin Invest , vol.101 , pp. 877-89
    • Koenig, A.1    Norgard-Sumnicht, K.2    Linhardt, R.3
  • 27
    • 0036308072 scopus 로고    scopus 로고
    • Heparin's anti-inflammatory effects require glucosamine 6-O-sulfation and are mediated by blockade of L- and P-selectins
    • L Wang JR Brown A Varki 2002 Heparin's anti-inflammatory effects require glucosamine 6-O-sulfation and are mediated by blockade of L- and P-selectins J Clin Invest 110 127 36
    • (2002) J Clin Invest , vol.110 , pp. 127-36
    • Wang, L.1    Brown, J.R.2    Varki, A.3
  • 29
    • 0034235315 scopus 로고    scopus 로고
    • Heparan sulfate-like proteoglycans mediate adhesion of human malignant melanoma A375 cells to P-selectin under flow
    • A-Q Ma J-G. Geng 2000 Heparan sulfate-like proteoglycans mediate adhesion of human malignant melanoma A375 cells to P-selectin under flow J Immunol 165 558 65
    • (2000) J Immunol , vol.165 , pp. 558-65
    • Ma, A.-Q.1    Geng, J.-G.2
  • 30
    • 0035166482 scopus 로고    scopus 로고
    • Expression of CD44v3 splice variant is associated with the visceral metastatic phenotype of human melanoma
    • B Döme B Somlai A Ladányi 2001 Expression of CD44v3 splice variant is associated with the visceral metastatic phenotype of human melanoma Virchows Arch 439 628 35
    • (2001) Virchows Arch , vol.439 , pp. 628-35
    • Döme, B.1    Somlai, B.2    Ladányi, A.3
  • 31
    • 0035988837 scopus 로고    scopus 로고
    • Proteoglycans and tumor progression: Janus-faced molecules with contradictory functions in cancer
    • J Tímár K Lapis J Dudás 2002 Proteoglycans and tumor progression: Janus-faced molecules with contradictory functions in cancer Sem Cancer Biol 12 173 86
    • (2002) Sem Cancer Biol , vol.12 , pp. 173-86
    • Tímár, J.1    Lapis, K.2    Dudás, J.3
  • 32
    • 0029157278 scopus 로고
    • Modulation of heparan-sulphate/chondroitin-sulphate ratio by glycosaminoglycan biosynthesis inhibitors affects liver metastatic potential of tumor cells
    • J Tímár CS Diczházi I Bartha 1995 Modulation of heparan-sulphate/chondroitin-sulphate ratio by glycosaminoglycan biosynthesis inhibitors affects liver metastatic potential of tumor cells Int J Cancer 62 755 61
    • (1995) Int J Cancer , vol.62 , pp. 755-61
    • Tímár, J.1    Diczházi, C.S.2    Bartha, I.3
  • 33
    • 0036765642 scopus 로고    scopus 로고
    • Basic HGF-like peptides inhibit generation of liver metastases in murine and human tumor models
    • K Fazekas E Rásó M Zarándi 2002 Basic HGF-like peptides inhibit generation of liver metastases in murine and human tumor models Anticancer Res 22 2575 80
    • (2002) Anticancer Res , vol.22 , pp. 2575-80
    • Fazekas, K.1    Rásó, E.2    Zarándi, M.3
  • 34
    • 0347659492 scopus 로고    scopus 로고
    • Heparin modulates integrin-mediated cellular adhesion: Specificity of interactions with alpha and beta integrin subunits
    • MS Da Silva JA Horton JM Wijelath 2003 Heparin modulates integrin-mediated cellular adhesion: Specificity of interactions with alpha and beta integrin subunits Cell Commun Adhes 10 59 67
    • (2003) Cell Commun Adhes , vol.10 , pp. 59-67
    • Da Silva, M.S.1    Horton, J.A.2    Wijelath, J.M.3
  • 35
    • 0037055956 scopus 로고    scopus 로고
    • Role for β3 integrins in human melanoma growth and survival
    • M Trikha J Tímár A Zacharek 2002 Role for β3 integrins in human melanoma growth and survival Int J Cancer 101 156 67
    • (2002) Int J Cancer , vol.101 , pp. 156-67
    • Trikha, M.1    Tímár, J.2    Zacharek, A.3
  • 36
    • 0037092984 scopus 로고    scopus 로고
    • Multiple roles for platelet gpIIb/IIIa and αvβ3 integrins in tumor growth, angiogenesis and metastasis
    • M Trikha Z Zhou J Tímár 2002 Multiple roles for platelet gpIIb/IIIa and αvβ3 integrins in tumor growth, angiogenesis and metastasis Cancer Res 62 2824 833
    • (2002) Cancer Res , vol.62 , pp. 2824-833
    • Trikha, M.1    Zhou, Z.2    Tímár, J.3
  • 37
    • 0038049137 scopus 로고    scopus 로고
    • Cell-cell invasion and migration: Diversity and escape mechanisms
    • P Friedl K. Wolf 2003 Cell-cell invasion and migration: Diversity and escape mechanisms Nat Rev Cancer 3 362 74
    • (2003) Nat Rev Cancer , vol.3 , pp. 362-74
    • Friedl, P.1    Wolf, K.2
  • 38
    • 0142245603 scopus 로고    scopus 로고
    • Amoeboid shape change and contact guidance: T-lymphocyte crawling through fibrillar collagen is independent of matrix remodeling by MMPs and other proteases
    • K Wolf R Müller S Borgmann 2003 Amoeboid shape change and contact guidance: T-lymphocyte crawling through fibrillar collagen is independent of matrix remodeling by MMPs and other proteases Blood 102 3262 9
    • (2003) Blood , vol.102 , pp. 3262-9
    • Wolf, K.1    Müller, R.2    Borgmann, S.3
  • 39
    • 0036622701 scopus 로고    scopus 로고
    • Can low-molecular-weight heparins improve outcome in patients with cancer?
    • P Thodiyil AK. Kakkar 2002 Can low-molecular-weight heparins improve outcome in patients with cancer? Cancer Treat Rev 28 151 5
    • (2002) Cancer Treat Rev , vol.28 , pp. 151-5
    • Thodiyil, P.1    Kakkar, A.K.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.