-
2
-
-
84888875876
-
Advances in regenerative orthopedics
-
C.H. Evans Advances in regenerative orthopedics Mayo Clin. Proc. 88 2013 1323 1339
-
(2013)
Mayo Clin. Proc.
, vol.88
, pp. 1323-1339
-
-
Evans, C.H.1
-
3
-
-
34250019537
-
Bone: Formation by autoinduction
-
M.R. Urist Bone: formation by autoinduction Science 150 1965 893 899
-
(1965)
Science
, vol.150
, pp. 893-899
-
-
Urist, M.R.1
-
4
-
-
0036599845
-
The role of growth factors in the repair of bone. Biology and clinical applications
-
J.R. Lieberman et al. The role of growth factors in the repair of bone. Biology and clinical applications J. Bone Joint Surg. Am. 84 2002 1032 1044
-
(2002)
J. Bone Joint Surg. Am.
, vol.84
, pp. 1032-1044
-
-
Lieberman, J.R.1
-
5
-
-
49349090133
-
Bone morphogenetic proteins in tissue engineering: The road from laboratory to clinic, part II (BMP delivery)
-
P.C. Bessa et al. Bone morphogenetic proteins in tissue engineering: the road from laboratory to clinic, part II (BMP delivery) J. Tissue Eng. Regen. Med. 2 2008 81 96
-
(2008)
J. Tissue Eng. Regen. Med.
, vol.2
, pp. 81-96
-
-
Bessa, P.C.1
-
6
-
-
84865291114
-
Studies of bone morphogenetic protein based surgical repair
-
K.W-H. Lo et al. Studies of bone morphogenetic protein based surgical repair Adv. Drug Deliv. Rev. 64 2012 1277 1291
-
(2012)
Adv. Drug Deliv. Rev.
, vol.64
, pp. 1277-1291
-
-
Lo, K.W.-H.1
-
7
-
-
84885593263
-
Combined angiogenic and osteogenic factor delivery for bone regenerative engineering
-
Q. Cui et al. Combined angiogenic and osteogenic factor delivery for bone regenerative engineering Curr. Pharm. Des. 19 2013 3374 3383
-
(2013)
Curr. Pharm. Des.
, vol.19
, pp. 3374-3383
-
-
Cui, Q.1
-
8
-
-
0029944347
-
Macromolecular versus small-molecule therapeutics: Drug discovery, development and clinical considerations
-
DOI 10.1016/0167-7799(96)10024-X
-
M.J. Cho, and R. Juliano Macromolecular versus small-molecule therapeutics: drug discovery, development and clinical considerations Trends Biotechnol. 14 1996 153 158 (Pubitemid 26163446)
-
(1996)
Trends in Biotechnology
, vol.14
, Issue.5
, pp. 153-158
-
-
Cho, M.J.1
Juliano, R.2
-
9
-
-
77958483948
-
Pre-clinical considerations in the assessment of immunogenicity for protein therapeutics
-
M. Baker, and F. Carr Pre-clinical considerations in the assessment of immunogenicity for protein therapeutics Curr. Drug Saf. 5 2010 308 313
-
(2010)
Curr. Drug Saf.
, vol.5
, pp. 308-313
-
-
Baker, M.1
Carr, F.2
-
10
-
-
80055108494
-
Current patents on osteoinductive molecules for bone tissue engineering
-
K.W. Lo et al. Current patents on osteoinductive molecules for bone tissue engineering Recent Pat. Biomed. Eng. 4 2011 153 167
-
(2011)
Recent Pat. Biomed. Eng.
, vol.4
, pp. 153-167
-
-
Lo, K.W.1
-
11
-
-
84864264096
-
The role of small molecules in the musculoskeletal regeneration
-
K.W-H. Lo et al. The role of small molecules in the musculoskeletal regeneration Regen. Med. 7 2012 535 549
-
(2012)
Regen. Med.
, vol.7
, pp. 535-549
-
-
Lo, K.W.-H.1
-
12
-
-
84884583510
-
The role of small molecules in bone regeneration
-
Q.Q. Han et al. The role of small molecules in bone regeneration Future Med. Chem. 5 2013 1671 1684
-
(2013)
Future Med. Chem.
, vol.5
, pp. 1671-1684
-
-
Han, Q.Q.1
-
13
-
-
0033987939
-
Protein stability in controlled-release systems
-
DOI 10.1038/71875
-
K. Fu et al. Protein stability in controlled-release systems Nat. Biotechnol. 18 2000 24 25 (Pubitemid 30041164)
-
(2000)
Nature Biotechnology
, vol.18
, Issue.1
, pp. 24-25
-
-
Fu, K.1
Klibanov, A.M.2
Langer, R.3
-
14
-
-
33748682929
-
Immunogenicity of biopharmaceuticals
-
M. Kessler et al. Immunogenicity of biopharmaceuticals Nephrol. Dial. Transplant. 21 Suppl. 5 2006 v9 v12
-
(2006)
Nephrol. Dial. Transplant.
, vol.21
, Issue.SUPPL. 5
-
-
Kessler, M.1
-
15
-
-
66449136302
-
Immunogenicity of bone morphogenetic proteins
-
C.J. Hwang et al. Immunogenicity of bone morphogenetic proteins J. Neurosurg. Spine 10 2009 443 451
-
(2009)
J. Neurosurg. Spine
, vol.10
, pp. 443-451
-
-
Hwang, C.J.1
-
16
-
-
77958552691
-
A small-molecule approach to bone regenerative medicine in dentistry
-
H. Egusa et al. A small-molecule approach to bone regenerative medicine in dentistry J. Oral Biosci. 52 2010 107 118
-
(2010)
J. Oral Biosci.
, vol.52
, pp. 107-118
-
-
Egusa, H.1
-
17
-
-
84880806595
-
Regulation of angiogenesis and bone regeneration with natural and synthetic small molecules
-
C.E. Segar et al. Regulation of angiogenesis and bone regeneration with natural and synthetic small molecules Curr. Pharm. Des. 19 2013 3403 3419
-
(2013)
Curr. Pharm. Des.
, vol.19
, pp. 3403-3419
-
-
Segar, C.E.1
-
18
-
-
84892891393
-
Small molecule based musculoskeletal regenerative engineering
-
K.W-H. Lo et al. Small molecule based musculoskeletal regenerative engineering Trends Biotechnol. 32 2014 74 81
-
(2014)
Trends Biotechnol.
, vol.32
, pp. 74-81
-
-
Lo, K.W.-H.1
-
19
-
-
80055102634
-
Overview: Differentiating issues in the development of macromolecules compared with small molecules
-
S.C. Gad, John Wiley & Sons 10.1002/9780470117118.ch1c
-
G. Blaich et al. Overview: differentiating issues in the development of macromolecules compared with small molecules S.C. Gad, Handbook of Pharmaceutical Biotechnology 2006 John Wiley & Sons 10.1002/9780470117118. ch1c
-
(2006)
Handbook of Pharmaceutical Biotechnology
-
-
Blaich, G.1
-
20
-
-
33746729750
-
Small molecule inducers of angiogenesis for tissue engineering
-
DOI 10.1089/ten.2006.12.1903
-
K.A. Wieghaus et al. Small molecule inducers of angiogenesis for tissue engineering Tissue Eng. 12 2006 1903 1913 (Pubitemid 44162849)
-
(2006)
Tissue Engineering
, vol.12
, Issue.7
, pp. 1903-1913
-
-
Wieghaus, K.A.1
Capitosti, S.M.2
Anderson, C.R.3
Price, R.J.4
Blackman, B.R.5
Brown, M.L.6
Botchwey, E.A.7
-
21
-
-
52949105725
-
Development of high-throughput screening system for osteogenic drugs using a cell-based sensor
-
H. Hojo et al. Development of high-throughput screening system for osteogenic drugs using a cell-based sensor Biochem. Biophys. Res. Commun. 376 2008 375 379
-
(2008)
Biochem. Biophys. Res. Commun.
, vol.376
, pp. 375-379
-
-
Hojo, H.1
-
22
-
-
60449088467
-
Small molecules with potent osteogenic-inducing activity in osteoblast cells
-
C.Y. Han et al. Small molecules with potent osteogenic-inducing activity in osteoblast cells Bioorg. Med. Chem. Lett. 19 2009 1442 1445
-
(2009)
Bioorg. Med. Chem. Lett.
, vol.19
, pp. 1442-1445
-
-
Han, C.Y.1
-
23
-
-
78649392879
-
High-throughput screening of a small molecule library for promoters and inhibitors of mesenchymal stem cell osteogenic differentiation
-
D.M. Brey et al. High-throughput screening of a small molecule library for promoters and inhibitors of mesenchymal stem cell osteogenic differentiation Biotechnol. Bioeng. 108 2011 163 174
-
(2011)
Biotechnol. Bioeng.
, vol.108
, pp. 163-174
-
-
Brey, D.M.1
-
24
-
-
80055044603
-
High-throughput assay for the identification of compounds regulating osteogenic differentiation of human mesenchymal stromal cells
-
H. Alves et al. High-throughput assay for the identification of compounds regulating osteogenic differentiation of human mesenchymal stromal cells PLoS ONE 6 2011 e26678
-
(2011)
PLoS ONE
, vol.6
, pp. 26678
-
-
Alves, H.1
-
25
-
-
84860835899
-
A novel library screen identifies immunosuppressors that promote osteoblast differentiation
-
A. Darcy et al. A novel library screen identifies immunosuppressors that promote osteoblast differentiation Bone 50 2012 1294 1303
-
(2012)
Bone
, vol.50
, pp. 1294-1303
-
-
Darcy, A.1
-
26
-
-
84875092554
-
Identification of small molecule activators of BMP signaling
-
K. Vrijens et al. Identification of small molecule activators of BMP signaling PLoS ONE 8 2013 e59045
-
(2013)
PLoS ONE
, vol.8
, pp. 59045
-
-
Vrijens, K.1
-
28
-
-
0022322336
-
Microencapsulation and controlled release of insulin from polylactic acid microcapsules
-
S.Y. Lin et al. Microencapsulation and controlled release of insulin from polylactic acid microcapsules Biomater. Med. Devices Artif. Organs 13 1985 187 201
-
(1985)
Biomater. Med. Devices Artif. Organs
, vol.13
, pp. 187-201
-
-
Lin, S.Y.1
-
30
-
-
0028205133
-
Biodegradable microspheres as controlled-release tetanus toxoid delivery systems
-
DOI 10.1016/0264-410X(94)90092-2
-
M.J. Alonso et al. Biodegradable microspheres as controlled-release tetanus toxoid delivery systems Vaccine 12 1994 299 306 (Pubitemid 24071950)
-
(1994)
Vaccine
, vol.12
, Issue.4
, pp. 299-306
-
-
Alonso, M.J.1
Gupta, R.K.2
Min, C.3
Siber, G.R.4
Langer, R.5
-
31
-
-
0034002855
-
Controlled release of β-estradiol from PLAGA microparticles: The effect of organic phase solvent on encapsulation and release
-
DOI 10.1016/S0168-3659(99)00219-9, PII S0168365999002199
-
D.T. Birnbaum et al. Controlled release of beta-estradiol from PLAGA microparticles: the effect of organic phase solvent on encapsulation and release J. Control. Release 65 2000 375 387 (Pubitemid 30122940)
-
(2000)
Journal of Controlled Release
, vol.65
, Issue.3
, pp. 375-387
-
-
Birnbaum, D.T.1
Kosmala, J.D.2
Henthorn, D.B.3
Brannon-Peppas, L.4
-
32
-
-
0028907285
-
Preparation and characterization of 5-fluorouracil-loaded microparticles as biodegradable anticancer drug carriers
-
M. Boisdron-Celle et al. Preparation and characterization of 5-fluorouracil-loaded microparticles as biodegradable anticancer drug carriers J. Pharm. Pharmacol. 47 1995 108 114
-
(1995)
J. Pharm. Pharmacol.
, vol.47
, pp. 108-114
-
-
Boisdron-Celle, M.1
-
33
-
-
78649633829
-
Small-molecule delivery by nanoparticles for anticancer therapy
-
Z.G. Chen Small-molecule delivery by nanoparticles for anticancer therapy Trends Mol. Med. 16 2010 594 602
-
(2010)
Trends Mol. Med.
, vol.16
, pp. 594-602
-
-
Chen, Z.G.1
-
34
-
-
84897376216
-
Polymeric scaffolds in tissue engineering application: A review
-
10.1155/2011/290602
-
B. Dhandayuthapani et al. Polymeric scaffolds in tissue engineering application: a review Int. J. Polym. Sci. 2011 10.1155/2011/290602
-
(2011)
Int. J. Polym. Sci.
-
-
Dhandayuthapani, B.1
-
35
-
-
4544273208
-
Bone tissue engineering: State of the art and future trends
-
DOI 10.1002/mabi.200400026
-
A.J. Salgado et al. Bone tissue engineering: state of the art and future trends Macromol. Biosci. 4 2004 743 765 (Pubitemid 39257140)
-
(2004)
Macromolecular Bioscience
, vol.4
, Issue.8
, pp. 743-765
-
-
Salgado, A.J.1
Coutinho, O.P.2
Reis, R.L.3
-
37
-
-
84880920195
-
Calcium phosphate ceramics in bone tissue engineering: A review of properties and their influence on cell behavior
-
S. Samavedi et al. Calcium phosphate ceramics in bone tissue engineering: a review of properties and their influence on cell behavior Acta Biomater. 9 2013 8037 8045
-
(2013)
Acta Biomater.
, vol.9
, pp. 8037-8045
-
-
Samavedi, S.1
-
38
-
-
34249938497
-
Matrices and scaffolds for delivery of bioactive molecules in bone and cartilage tissue engineering
-
DOI 10.1016/j.addr.2007.03.016, PII S0169409X07000324, Matrices and Scaffolds for Drug Delivery in Tissue Engineering
-
S.H. Lee, and H. Shin Matrices and scaffolds for delivery of bioactive molecules in bone and cartilage tissue engineering Adv. Drug Deliv. Rev. 59 2007 339 359 (Pubitemid 46879973)
-
(2007)
Advanced Drug Delivery Reviews
, vol.59
, Issue.4-5
, pp. 339-359
-
-
Lee, S.-H.1
Shin, H.2
-
39
-
-
83655165245
-
Poly lactic-co-glycolic acid (PLGA) as biodegradable controlled drug delivery carrier
-
H.K. Makadia, and S.J. Siege Poly lactic-co-glycolic acid (PLGA) as biodegradable controlled drug delivery carrier Polymers 3 2011 1377 1397
-
(2011)
Polymers
, vol.3
, pp. 1377-1397
-
-
Makadia, H.K.1
Siege, S.J.2
-
40
-
-
84880860067
-
Advances in chitosan-based drug delivery vehicles
-
L. Hu et al. Advances in chitosan-based drug delivery vehicles Nanoscale 5 2013 3103 3111
-
(2013)
Nanoscale
, vol.5
, pp. 3103-3111
-
-
Hu, L.1
-
41
-
-
34547197434
-
Enhanced bone regeneration with BMP-2 loaded functional nanoparticle-hydrogel complex
-
Y.I. Chung et al. Enhanced bone regeneration with BMP-2 loaded functional nanoparticle-hydrogel complex J. Control. Release 121 2007 91 99
-
(2007)
J. Control. Release
, vol.121
, pp. 91-99
-
-
Chung, Y.I.1
-
42
-
-
84885024380
-
Functionalization of biomaterials with small osteoinductive moieties
-
F.R. Maia et al. Functionalization of biomaterials with small osteoinductive moieties Acta Biomater. 9 2013 8773 8789
-
(2013)
Acta Biomater.
, vol.9
, pp. 8773-8789
-
-
Maia, F.R.1
-
44
-
-
67650088426
-
The basics of preclinical drug development for neurodegenerative disease indications
-
K.L. Steinmetz, and E.G. Spack The basics of preclinical drug development for neurodegenerative disease indications BMC Neurol. 9 Suppl. 1 2009 S2
-
(2009)
BMC Neurol.
, vol.9
, Issue.SUPPL. 1
, pp. 2
-
-
Steinmetz, K.L.1
Spack, E.G.2
-
45
-
-
80054110436
-
Osteoporosis: New treatments and updates
-
S. Honig Osteoporosis: new treatments and updates Bull. NYU Hosp. Jt. Dis. 69 2010 253 256
-
(2010)
Bull. NYU Hosp. Jt. Dis.
, vol.69
, pp. 253-256
-
-
Honig, S.1
-
46
-
-
84877022835
-
The pathogenesis, treatment and prevention of osteoporosis in men
-
L. Mosekilde et al. The pathogenesis, treatment and prevention of osteoporosis in men Drugs 73 2013 15 29
-
(2013)
Drugs
, vol.73
, pp. 15-29
-
-
Mosekilde, L.1
-
47
-
-
0042591734
-
Recombinant human PTH 1-34 (Forteo): An anabolic drug for osteoporosis
-
C. Deal, and J. Gideon Recombinant human PTH 1-34 (Forteo): an anabolic drug for osteoporosis Cleve. Clin. J. Med. 70 2003 585 601 (Pubitemid 36939959)
-
(2003)
Cleveland Clinic Journal of Medicine
, vol.70
, Issue.7
, pp. 585-601
-
-
Deal, C.1
Gideon, J.2
-
48
-
-
83755196135
-
Modes of degradation and impurity characterization in rhPTH (1-34) during stability studies
-
R. Kothari et al. Modes of degradation and impurity characterization in rhPTH (1-34) during stability studies PDA J. Pharm. Sci. Technol. 65 2011 348 362
-
(2011)
PDA J. Pharm. Sci. Technol.
, vol.65
, pp. 348-362
-
-
Kothari, R.1
-
49
-
-
0033521078
-
Stimulation of bone formation in vitro and in rodents by statins
-
G. Mundy et al. Stimulation of bone formation in vitro and in rodents by statins Science 286 1999 1946 1949 (Pubitemid 129515901)
-
(1999)
Science
, vol.286
, Issue.5446
, pp. 1946-1949
-
-
Mundy, G.1
Garrett, R.2
Harris, S.3
Chan, J.4
Chen, D.5
Rossini, G.6
Boyce, B.7
Zhao, M.8
Gutierrez, G.9
-
50
-
-
84868130690
-
Statins and hip fracture prevention: A population based cohort study in women
-
A. Helin-Salmivaara et al. Statins and hip fracture prevention: a population based cohort study in women PLoS ONE 7 2012 e48095
-
(2012)
PLoS ONE
, vol.7
, pp. 48095
-
-
Helin-Salmivaara, A.1
-
51
-
-
84863331085
-
Preparation of injectable auto-forming alginate gel containing simvastatin with amorphous calcium phosphate as a controlled release medium and their therapeutic effect in osteoporosis model rat
-
T. Ito et al. Preparation of injectable auto-forming alginate gel containing simvastatin with amorphous calcium phosphate as a controlled release medium and their therapeutic effect in osteoporosis model rat J. Mater. Sci. Mater. Med. 23 2012 1291 1297
-
(2012)
J. Mater. Sci. Mater. Med.
, vol.23
, pp. 1291-1297
-
-
Ito, T.1
-
52
-
-
84875245788
-
Preparation of calcium phosphate nanocapsules including simvastatin/deoxycholic acid assembly, and their therapeutic effect in osteoporosis model mice
-
T. Ito et al. Preparation of calcium phosphate nanocapsules including simvastatin/deoxycholic acid assembly, and their therapeutic effect in osteoporosis model mice J. Pharm. Pharmacol. 65 2013 494 502
-
(2013)
J. Pharm. Pharmacol.
, vol.65
, pp. 494-502
-
-
Ito, T.1
-
53
-
-
58449130151
-
Effects of simvastatin on bone healing around titanium implants in osteoporotic rats
-
Z. Du et al. Effects of simvastatin on bone healing around titanium implants in osteoporotic rats Clin. Oral Implants Res. 20 2009 145 150
-
(2009)
Clin. Oral Implants Res.
, vol.20
, pp. 145-150
-
-
Du, Z.1
-
54
-
-
84873019241
-
Bone responses to simvastatin-loaded porous implant surfaces in an ovariectomized model
-
G. Yang et al. Bone responses to simvastatin-loaded porous implant surfaces in an ovariectomized model Int. J. Oral Maxillofac. Implants 27 2012 369 374
-
(2012)
Int. J. Oral Maxillofac. Implants
, vol.27
, pp. 369-374
-
-
Yang, G.1
-
55
-
-
53749087447
-
Implants delivering bisphosphonate locally increase periprosthetic bone density in an osteoporotic sheep model. A pilot study
-
V.A. Stadelmann et al. Implants delivering bisphosphonate locally increase periprosthetic bone density in an osteoporotic sheep model. A pilot study Eur. Cell Mater. 16 2008 10 16
-
(2008)
Eur. Cell Mater.
, vol.16
, pp. 10-16
-
-
Stadelmann, V.A.1
-
56
-
-
0029705294
-
Bone biology. I: Structure, blood supply, cells, matrix, and mineralization
-
J.A. Buckwalter et al. Bone biology. I: structure, blood supply, cells, matrix, and mineralization Instr. Course Lect. 45 1996 371 386
-
(1996)
Instr. Course Lect.
, vol.45
, pp. 371-386
-
-
Buckwalter, J.A.1
-
57
-
-
18744380377
-
The biology of bone grafting
-
S.N. Khan et al. The biology of bone grafting J. Am. Acad. Orthop. Surg. 13 2005 77 86
-
(2005)
J. Am. Acad. Orthop. Surg.
, vol.13
, pp. 77-86
-
-
Khan, S.N.1
-
60
-
-
77953963056
-
The enhancement of bone allograft incorporation by the local delivery of the sphingosine 1-phosphate receptor targeted drug FTY720
-
C.E. Petrie Aronin et al. The enhancement of bone allograft incorporation by the local delivery of the sphingosine 1-phosphate receptor targeted drug FTY720 Biomaterials 31 2010 6417 6424
-
(2010)
Biomaterials
, vol.31
, pp. 6417-6424
-
-
Petrie Aronin, C.E.1
-
61
-
-
79952163918
-
Selective activation of sphingosine 1-phosphate receptors 1 and 3 promotes local microvascular network growth
-
L.S. Sefcik et al. Selective activation of sphingosine 1-phosphate receptors 1 and 3 promotes local microvascular network growth Tissue Eng. A 17 2011 617 629
-
(2011)
Tissue Eng. A
, vol.17
, pp. 617-629
-
-
Sefcik, L.S.1
-
62
-
-
84860389144
-
Local delivery of FTY720 accelerates cranial allograft incorporation and bone formation
-
C. Huang et al. Local delivery of FTY720 accelerates cranial allograft incorporation and bone formation Cell Tissue Res. 347 2012 553 566
-
(2012)
Cell Tissue Res.
, vol.347
, pp. 553-566
-
-
Huang, C.1
-
63
-
-
4644250693
-
Purmorphamine induces osteogenesis by activation of the Hedgehog signaling pathway
-
DOI 10.1016/j.chembiol.2004.06.010, PII S1074552104002212
-
X. Wu et al. Purmorphamine induces osteogenesis by activation of the Hedgehog signaling pathway Chem. Biol. 11 2004 1229 1238 (Pubitemid 39282798)
-
(2004)
Chemistry and Biology
, vol.11
, Issue.9
, pp. 1229-1238
-
-
Wu, X.1
Walker, J.2
Zhang, J.3
Ding, S.4
Schultz, P.G.5
-
64
-
-
84885169341
-
Small molecule stimulation enhances bone regeneration but not titanium implant osseointegration
-
K. Gellynck et al. Small molecule stimulation enhances bone regeneration but not titanium implant osseointegration Bone 57 2013 405 412
-
(2013)
Bone
, vol.57
, pp. 405-412
-
-
Gellynck, K.1
-
65
-
-
67650091148
-
The small molecule phenamil induces osteoblast differentiation and mineralization
-
K.W. Park et al. The small molecule phenamil induces osteoblast differentiation and mineralization Mol. Cell. Biol. 29 2009 3905 3914
-
(2009)
Mol. Cell. Biol.
, vol.29
, pp. 3905-3914
-
-
Park, K.W.1
-
66
-
-
79952283228
-
A synthetic compound that potentiates bone morphogenetic protein-2-induced transdifferentiation of myoblasts into the osteoblastic phenotype
-
S. Kato et al. A synthetic compound that potentiates bone morphogenetic protein-2-induced transdifferentiation of myoblasts into the osteoblastic phenotype Mol. Cell. Biochem. 349 2011 97 106
-
(2011)
Mol. Cell. Biochem.
, vol.349
, pp. 97-106
-
-
Kato, S.1
-
67
-
-
84876433078
-
A novel low-molecular-weight compound enhances ectopic bone formation and fracture repair
-
E. Wong et al. A novel low-molecular-weight compound enhances ectopic bone formation and fracture repair J. Bone Joint Surg. Am. 95 2013 454 461
-
(2013)
J. Bone Joint Surg. Am.
, vol.95
, pp. 454-461
-
-
Wong, E.1
-
68
-
-
77953895506
-
Effect of Buguzhi (Psoralea corylifolia fruit) extract on bone formation
-
R.W. Wong, and A.B. Rabie Effect of Buguzhi (Psoralea corylifolia fruit) extract on bone formation Phytother. Res. 24 Suppl. 2 2010 S155 S160
-
(2010)
Phytother. Res.
, vol.24
, Issue.SUPPL. 2
-
-
Wong, R.W.1
Rabie, A.B.2
-
69
-
-
78650964953
-
Effect of psoralen on bone formation
-
R.W. Wong, and A.B. Rabie Effect of psoralen on bone formation J. Orthop. Res. 29 2011 158 164
-
(2011)
J. Orthop. Res.
, vol.29
, pp. 158-164
-
-
Wong, R.W.1
Rabie, A.B.2
-
70
-
-
63849147284
-
Effect of daidzein on bone formation
-
R.W. Wong, and A.B. Rabie Effect of daidzein on bone formation Front. Biosci. 14 2009 3673 3679
-
(2009)
Front. Biosci.
, vol.14
, pp. 3673-3679
-
-
Wong, R.W.1
Rabie, A.B.2
-
71
-
-
77954517233
-
Effect of genistin on bone formation
-
R.W. Wong, and A.B. Rabie Effect of genistin on bone formation Front. Biosci. 2 2010 764 770
-
(2010)
Front. Biosci.
, vol.2
, pp. 764-770
-
-
Wong, R.W.1
Rabie, A.B.2
-
72
-
-
85056054363
-
Effect of quercetin on preosteoblasts and bone defects
-
R.W. Wong, and A.B. Rabie Effect of quercetin on preosteoblasts and bone defects Open Orthop. J. 2 2008 27 32
-
(2008)
Open Orthop. J.
, vol.2
, pp. 27-32
-
-
Wong, R.W.1
Rabie, A.B.2
-
73
-
-
84885764642
-
Local delivery of controlled-release simvastatin/PLGA/HAp microspheres enhances bone repair
-
I.C. Tai et al. Local delivery of controlled-release simvastatin/PLGA/HAp microspheres enhances bone repair Int. J. Nanomed. 8 2013 3895 3905
-
(2013)
Int. J. Nanomed.
, vol.8
, pp. 3895-3905
-
-
Tai, I.C.1
-
74
-
-
84862777340
-
Mobilization of bone marrow mesenchymal stem cells in vivo augments bone healing in a mouse model of segmental bone defect
-
S. Kumar, and S. Ponnazhagan Mobilization of bone marrow mesenchymal stem cells in vivo augments bone healing in a mouse model of segmental bone defect Bone 50 2012 1012 1018
-
(2012)
Bone
, vol.50
, pp. 1012-1018
-
-
Kumar, S.1
Ponnazhagan, S.2
-
75
-
-
84861159286
-
OIC-A006-loaded true bone ceramic heals rabbit critical-sized segmental radial defect
-
H. Shao et al. OIC-A006-loaded true bone ceramic heals rabbit critical-sized segmental radial defect Pharmazie 67 2012 247 252
-
(2012)
Pharmazie
, vol.67
, pp. 247-252
-
-
Shao, H.1
-
76
-
-
84878628955
-
N-acetyl cysteine as an osteogenesis-enhancing molecule for bone regeneration
-
M. Yamada et al. N-acetyl cysteine as an osteogenesis-enhancing molecule for bone regeneration Biomaterials 34 2013 6147 6156
-
(2013)
Biomaterials
, vol.34
, pp. 6147-6156
-
-
Yamada, M.1
-
77
-
-
70349603208
-
Diagnosis and surgical treatment of back pain originating from endplate
-
B. Peng et al. Diagnosis and surgical treatment of back pain originating from endplate Eur. Spine J. 18 2009 1035 1040
-
(2009)
Eur. Spine J.
, vol.18
, pp. 1035-1040
-
-
Peng, B.1
-
78
-
-
57349105550
-
The cellular pathobiology of the degenerate intervertebral disc and discogenic back pain
-
A.J. Freemont The cellular pathobiology of the degenerate intervertebral disc and discogenic back pain Rheumatology 48 2009 5 10
-
(2009)
Rheumatology
, vol.48
, pp. 5-10
-
-
Freemont, A.J.1
-
79
-
-
0642307048
-
Spine-tingling prospects: Artificial disc implants are among the new technologies expected to revolutionize the outcomes of back surgery
-
C. Becker Spine-tingling prospects: artificial disc implants are among the new technologies expected to revolutionize the outcomes of back surgery Mod. Healthc. 33 2003 30 32
-
(2003)
Mod. Healthc.
, vol.33
, pp. 30-32
-
-
Becker, C.1
-
80
-
-
83255186931
-
Simvastatin improves spinal fusion in rats
-
B. Bostan et al. Simvastatin improves spinal fusion in rats Acta Orthop. Traumatol. Turc. 45 2011 270 275
-
(2011)
Acta Orthop. Traumatol. Turc.
, vol.45
, pp. 270-275
-
-
Bostan, B.1
-
81
-
-
33745551097
-
The use of simvastatin in rabbit posterolateral lumbar intertransverse process spine fusion
-
DOI 10.1016/j.spinee.2005.10.017, PII S1529943005010260
-
A.J. Yee et al. The use of simvastatin in rabbit posterolateral lumbar intertransverse process spine fusion Spine J. 6 2006 391 396 (Pubitemid 43977196)
-
(2006)
Spine Journal
, vol.6
, Issue.4
, pp. 391-396
-
-
Yee, A.J.M.1
Bae, H.W.2
Friess, D.3
Roth, S.M.4
Whyne, C.5
Robbin, M.6
Johnstone, B.7
Yoo, J.U.8
-
82
-
-
79954544086
-
Novel oxysterols have pro-osteogenic and anti-adipogenic effects in vitro and induce spinal fusion in vivo
-
J.S. Johnson et al. Novel oxysterols have pro-osteogenic and anti-adipogenic effects in vitro and induce spinal fusion in vivo J. Cell. Biochem. 112 2011 1673 1684
-
(2011)
J. Cell. Biochem.
, vol.112
, pp. 1673-1684
-
-
Johnson, J.S.1
-
83
-
-
84865480185
-
Novel oxysterols activate the Hedgehog pathway and induce osteogenesis
-
F. Stappenbeck et al. Novel oxysterols activate the Hedgehog pathway and induce osteogenesis Bioorg. Med. Chem. Lett. 22 2012 5893 5897
-
(2012)
Bioorg. Med. Chem. Lett.
, vol.22
, pp. 5893-5897
-
-
Stappenbeck, F.1
-
84
-
-
79960238966
-
Network neighbors of drug targets contribute to drug side-effect similarity
-
L. Brouwers et al. Network neighbors of drug targets contribute to drug side-effect similarity PLoS ONE 6 2011 e22187
-
(2011)
PLoS ONE
, vol.6
, pp. 22187
-
-
Brouwers, L.1
-
85
-
-
36249031068
-
Recognizing and exploiting differences between RNAi and small-molecule inhibitors
-
DOI 10.1038/nchembio1207-739, PII NCHEMBIO1207739
-
W.A. Weiss et al. Recognizing and exploiting differences between RNAi and small-molecule inhibitors Nat. Chem. Biol. 3 2007 739 744 (Pubitemid 350126879)
-
(2007)
Nature Chemical Biology
, vol.3
, Issue.12
, pp. 739-744
-
-
Weiss, W.A.1
Taylor, S.S.2
Shokat, K.M.3
-
86
-
-
85027952550
-
One-day treatment of small molecule 8-bromo-cyclic amp analogue induces cell-based VEGF production for in vitro angiogenesis and osteoblastic differentiation
-
10.1002/term.1839
-
K-W.H. Lo et al. One-day treatment of small molecule 8-bromo-cyclic amp analogue induces cell-based VEGF production for in vitro angiogenesis and osteoblastic differentiation J. Tissue Eng. Regen. Med. 2013 10.1002/term.1839
-
(2013)
J. Tissue Eng. Regen. Med.
-
-
Lo, K.-W.H.1
-
87
-
-
84880733168
-
Short-term treatment of small molecule phenamil induced a protracted osteogenic effect on osteoblast-like MC3T3-E1 cells
-
10.1002/term.1786
-
K-W.H. Lo et al. Short-term treatment of small molecule phenamil induced a protracted osteogenic effect on osteoblast-like MC3T3-E1 cells J. Tissue Eng. Regen. Med. 2013 10.1002/term.1786
-
(2013)
J. Tissue Eng. Regen. Med.
-
-
Lo, K.-W.H.1
-
88
-
-
23144456487
-
Sustained activity and release of leuprolide acetate from an in situ forming polymeric implant
-
H.B. Ravivarapu et al. Sustained activity and release of leuprolide acetate from an in situ forming polymeric implant AAPS PharmSciTech 1 2000 E1
-
(2000)
AAPS PharmSciTech
, vol.1
, pp. 1
-
-
Ravivarapu, H.B.1
-
89
-
-
23744517121
-
Controlled release of rhBMP-2 loaded poly(dl-lactic-co-glycolic acid)/calcium phosphate cement composites in vivo
-
DOI 10.1016/j.jconrel.2005.04.018, PII S0168365905001896
-
P.Q. Ruhe et al. Controlled release of rhBMP-2 loaded poly(dl-lactic-co-glycolic acid)/calcium phosphate cement composites in vivo J. Control. Release 106 2005 162 171 (Pubitemid 41140091)
-
(2005)
Journal of Controlled Release
, vol.106
, Issue.1-2
, pp. 162-171
-
-
Ruhe, P.Q.1
Boerman, O.C.2
Russel, F.G.M.3
Spauwen, P.H.M.4
Mikos, A.G.5
Jansen, J.A.6
-
90
-
-
84875737923
-
Injectable implants for the sustained release of protein and peptide drugs
-
P. Agarwal, and I.D. Rupenthal Injectable implants for the sustained release of protein and peptide drugs Drug Discov. Today 18 2013 337 349
-
(2013)
Drug Discov. Today
, vol.18
, pp. 337-349
-
-
Agarwal, P.1
Rupenthal, I.D.2
-
91
-
-
84902088187
-
Facile fabrication of polyanhydride/anesthetic nanoparticles with tunable release kinetics
-
10.1002/adhm.201300521
-
B.D. Ulery et al. Facile fabrication of polyanhydride/anesthetic nanoparticles with tunable release kinetics Adv. Healthc. Mater. 2013 10.1002/adhm.201300521
-
(2013)
Adv. Healthc. Mater.
-
-
Ulery, B.D.1
-
92
-
-
78651379819
-
Polymers for drug delivery systems
-
W.B. Liechty et al. Polymers for drug delivery systems Annu. Rev. Chem. Biomol. Eng. 1 2010 149 173
-
(2010)
Annu. Rev. Chem. Biomol. Eng.
, vol.1
, pp. 149-173
-
-
Liechty, W.B.1
-
93
-
-
0032844767
-
Poly(acrylic acid) microspheres containing β-cyclodextrin: Loading and in vitro release of two dyes
-
DOI 10.1016/S0378-5173(99)00190-8, PII S0378517399001908
-
D.C. Bibby et al. Poly(acrylic acid) microspheres containing beta-cyclodextrin: loading and in vitro release of two dyes Int. J. Pharm. 187 1999 243 250 (Pubitemid 29443904)
-
(1999)
International Journal of Pharmaceutics
, vol.187
, Issue.2
, pp. 243-250
-
-
Bibby, D.C.1
Davies, N.M.2
Tucker, I.G.3
-
94
-
-
84858959483
-
Nanostructured polymeric scaffolds for orthopaedic regenerative engineering
-
M. Deng et al. Nanostructured polymeric scaffolds for orthopaedic regenerative engineering IEEE Trans. Nanobiosci. 11 2012 3 14
-
(2012)
IEEE Trans. Nanobiosci.
, vol.11
, pp. 3-14
-
-
Deng, M.1
-
95
-
-
84875468083
-
Mesenchymal stem cell sheet transplantation combined with locally released simvastatin enhances bone formation in a rat tibia osteotomy model
-
Y. Qi et al. Mesenchymal stem cell sheet transplantation combined with locally released simvastatin enhances bone formation in a rat tibia osteotomy model Cytotherapy 15 2013 44 56
-
(2013)
Cytotherapy
, vol.15
, pp. 44-56
-
-
Qi, Y.1
-
96
-
-
84904959567
-
Local injection of lovastatin in biodegradable polyurethane scaffolds enhances bone regeneration in a critical-sized segmental defect in rat femora
-
10.1002/term.1547
-
T. Yoshii et al. Local injection of lovastatin in biodegradable polyurethane scaffolds enhances bone regeneration in a critical-sized segmental defect in rat femora J. Tissue Eng. Regen. Med. 2012 10.1002/term.1547
-
(2012)
J. Tissue Eng. Regen. Med.
-
-
Yoshii, T.1
-
97
-
-
76949089977
-
In vivo performance of absorbable collagen sponges with rosuvastatin in critical-size cortical bone defects
-
M. Monjo et al. In vivo performance of absorbable collagen sponges with rosuvastatin in critical-size cortical bone defects Acta Biomater. 6 2010 1405 1412
-
(2010)
Acta Biomater.
, vol.6
, pp. 1405-1412
-
-
Monjo, M.1
-
98
-
-
84877586643
-
Bone healing by sterilizable calcium phosphate tetrapods eluting osteogenic molecules
-
Y. Maeda et al. Bone healing by sterilizable calcium phosphate tetrapods eluting osteogenic molecules Biomaterials 34 2013 5530 5537
-
(2013)
Biomaterials
, vol.34
, pp. 5530-5537
-
-
Maeda, Y.1
-
99
-
-
84864627979
-
Drug-eluting microfibrous patches for the local delivery of rolipram in spinal cord repair
-
T.L. Downing et al. Drug-eluting microfibrous patches for the local delivery of rolipram in spinal cord repair J. Control. Release 161 2012 910 917
-
(2012)
J. Control. Release
, vol.161
, pp. 910-917
-
-
Downing, T.L.1
|