-
3
-
-
78650842405
-
Growth factor delivery-based tissue engineering: general approaches and a review of recent developments
-
Lee K., et al. Growth factor delivery-based tissue engineering: general approaches and a review of recent developments. J. R. Soc. Interface 2010, 8:153-170.
-
(2010)
J. R. Soc. Interface
, vol.8
, pp. 153-170
-
-
Lee, K.1
-
4
-
-
77958483948
-
Pre-clinical considerations in the assessment of immunogenicity for protein therapeutics
-
Baker M., Carr F. Pre-clinical considerations in the assessment of immunogenicity for protein therapeutics. Curr. Drug Saf. 2010, 5:308-313.
-
(2010)
Curr. Drug Saf.
, vol.5
, pp. 308-313
-
-
Baker, M.1
Carr, F.2
-
5
-
-
77958552691
-
A small-molecule approach to bone regenerative medicine in dentistry
-
Egusa H., et al. A small-molecule approach to bone regenerative medicine in dentistry. J. Oral Biosci. 2010, 52:107-118.
-
(2010)
J. Oral Biosci.
, vol.52
, pp. 107-118
-
-
Egusa, H.1
-
6
-
-
80055108494
-
Current patents on osteoinductive molecules for bone tissue engineering
-
Lo K.W., et al. Current patents on osteoinductive molecules for bone tissue engineering. Recent Patents Biomed. Eng. 2011, 4:153-167.
-
(2011)
Recent Patents Biomed. Eng.
, vol.4
, pp. 153-167
-
-
Lo, K.W.1
-
7
-
-
84880806595
-
Regulation of angiogenesis and bone regeneration with natural and synthetic small molecules
-
Segar C.E., et al. Regulation of angiogenesis and bone regeneration with natural and synthetic small molecules. Curr. Pharm. Des. 2013, 19:3403-3419.
-
(2013)
Curr. Pharm. Des.
, vol.19
, pp. 3403-3419
-
-
Segar, C.E.1
-
8
-
-
80055102634
-
Overview: differentiating issues in the development of macromolecules compared with small molecules
-
John Wiley
-
Blaich G., et al. Overview: differentiating issues in the development of macromolecules compared with small molecules. Handbook of Pharmaceutical Biotechnology 2006, 89-123. John Wiley.
-
(2006)
Handbook of Pharmaceutical Biotechnology
, pp. 89-123
-
-
Blaich, G.1
-
9
-
-
0033987939
-
Protein stability in controlled-release systems
-
Fu K., et al. Protein stability in controlled-release systems. Nat. Biotechnol. 2000, 18:24-25.
-
(2000)
Nat. Biotechnol.
, vol.18
, pp. 24-25
-
-
Fu, K.1
-
10
-
-
84864264096
-
The role of small molecules in the musculoskeletal regeneration
-
Lo K.W-H., et al. The role of small molecules in the musculoskeletal regeneration. Regen. Med. 2012, 7:535-549.
-
(2012)
Regen. Med.
, vol.7
, pp. 535-549
-
-
Lo, K.W.-H.1
-
11
-
-
36349024668
-
Current and future clinical applications of bone morphogenetic proteins in orthopaedic trauma surgery
-
Bishop G.B., Einhorn T.A. Current and future clinical applications of bone morphogenetic proteins in orthopaedic trauma surgery. Int. Orthop. 2007, 31:721-727.
-
(2007)
Int. Orthop.
, vol.31
, pp. 721-727
-
-
Bishop, G.B.1
Einhorn, T.A.2
-
12
-
-
49349090133
-
Bone morphogenetic proteins in tissue engineering: the road from laboratory to clinic, part II (BMP delivery)
-
Bessa P.C., et al. Bone morphogenetic proteins in tissue engineering: the road from laboratory to clinic, part II (BMP delivery). J. Tissue Eng. Regen. Med. 2008, 2:81-96.
-
(2008)
J. Tissue Eng. Regen. Med.
, vol.2
, pp. 81-96
-
-
Bessa, P.C.1
-
13
-
-
84865291114
-
Studies of bone morphogenetic protein based surgical repair
-
Lo K.W-H., et al. Studies of bone morphogenetic protein based surgical repair. Adv. Drug Deliv. Rev. 2012, 64:1277-1291.
-
(2012)
Adv. Drug Deliv. Rev.
, vol.64
, pp. 1277-1291
-
-
Lo, K.W.-H.1
-
14
-
-
84880722847
-
Complications associated with the use of the recombinant human bone morphogenetic proteins for posterior interbody fusions of the lumbar spine
-
Chrastil J., et al. Complications associated with the use of the recombinant human bone morphogenetic proteins for posterior interbody fusions of the lumbar spine. Spine 2013, 38:E1020-E1027.
-
(2013)
Spine
, vol.38
-
-
Chrastil, J.1
-
15
-
-
78149281054
-
Bone morphogenetic protein binding peptide mechanism and enhancement of osteogenic protein-1 induced bone healing
-
Taghavi C.E., et al. Bone morphogenetic protein binding peptide mechanism and enhancement of osteogenic protein-1 induced bone healing. Spine (Phila Pa 1976) 2010, 35:2049-2056.
-
(2010)
Spine (Phila Pa 1976)
, vol.35
, pp. 2049-2056
-
-
Taghavi, C.E.1
-
16
-
-
84883298054
-
Cancer after spinal fusion: the role of bone morphogenetic protein
-
Lad S.P., et al. Cancer after spinal fusion: the role of bone morphogenetic protein. Neurosurgery 2013, 73:440-449.
-
(2013)
Neurosurgery
, vol.73
, pp. 440-449
-
-
Lad, S.P.1
-
17
-
-
84876433078
-
A novel low-molecular-weight compound enhances ectopic bone formation and fracture repair
-
Wong E., et al. A novel low-molecular-weight compound enhances ectopic bone formation and fracture repair. J. Bone Joint Surg. 2013, 95:454-461.
-
(2013)
J. Bone Joint Surg.
, vol.95
, pp. 454-461
-
-
Wong, E.1
-
18
-
-
84875092554
-
Identification of small molecule activators of BMP signaling
-
Vrijens K., et al. Identification of small molecule activators of BMP signaling. PLoS ONE 2013, 8:e59045.
-
(2013)
PLoS ONE
, vol.8
-
-
Vrijens, K.1
-
19
-
-
34547882714
-
A novel regulatory mechanism of the bone morphogenetic protein (BMP) signaling pathway involving the carboxyl-terminal tail domain of BMP type II receptor
-
Chan M.C., et al. A novel regulatory mechanism of the bone morphogenetic protein (BMP) signaling pathway involving the carboxyl-terminal tail domain of BMP type II receptor. Mol. Cell. Biol. 2007, 27:5776-5789.
-
(2007)
Mol. Cell. Biol.
, vol.27
, pp. 5776-5789
-
-
Chan, M.C.1
-
20
-
-
84874647272
-
BMP signaling in development and diseases: a pharmacological perspective
-
Bandyopadhyay A., et al. BMP signaling in development and diseases: a pharmacological perspective. Biochem. Pharmacol. 2013, 85:857-864.
-
(2013)
Biochem. Pharmacol.
, vol.85
, pp. 857-864
-
-
Bandyopadhyay, A.1
-
21
-
-
79952283228
-
A synthetic compound that potentiates bone morphogenetic protein-2-induced transdifferentiation of myoblasts into the osteoblastic phenotype
-
Kato S., et al. A synthetic compound that potentiates bone morphogenetic protein-2-induced transdifferentiation of myoblasts into the osteoblastic phenotype. Mol. Cell. Biochem. 2011, 349:97-106.
-
(2011)
Mol. Cell. Biochem.
, vol.349
, pp. 97-106
-
-
Kato, S.1
-
22
-
-
84880733168
-
Short term treatment of small molecule phenamil induced a protracted osteogenic effect on osteoblast-like MC3T3-E1 cells
-
Lo K-W.H., et al. Short term treatment of small molecule phenamil induced a protracted osteogenic effect on osteoblast-like MC3T3-E1 cells. J. Tissue Eng. Regen. Med. 2013, 10.1002/term.1786.
-
(2013)
J. Tissue Eng. Regen. Med.
-
-
Lo, K.-W.H.1
-
23
-
-
84906940659
-
Evaluating the feasibility of utilizing small molecule phenamil as a novel biofactor factor for bone regenerative engineering
-
Lo K.W-H., et al. Evaluating the feasibility of utilizing small molecule phenamil as a novel biofactor factor for bone regenerative engineering. J. Tissue Eng. Regen. Med. 2012, 10.1002/term.1573.
-
(2012)
J. Tissue Eng. Regen. Med.
-
-
Lo, K.W.-H.1
-
24
-
-
67650091148
-
The small molecule phenamil induces osteoblast differentiation and mineralization
-
Park K.W., et al. The small molecule phenamil induces osteoblast differentiation and mineralization. Mol. Cell. Biol. 2009, 29:3905-3914.
-
(2009)
Mol. Cell. Biol.
, vol.29
, pp. 3905-3914
-
-
Park, K.W.1
-
25
-
-
84860835899
-
A novel library screen identifies immunosuppressors that promote osteoblast differentiation
-
Darcy A., et al. A novel library screen identifies immunosuppressors that promote osteoblast differentiation. Bone 2012, 50:1294-1303.
-
(2012)
Bone
, vol.50
, pp. 1294-1303
-
-
Darcy, A.1
-
26
-
-
84878245379
-
Bone morphogenetic protein-inducer tilorone identified by high-throughput screening is antifibrotic in vivo
-
Leppäranta O., et al. Bone morphogenetic protein-inducer tilorone identified by high-throughput screening is antifibrotic in vivo. Am. J. Respir. Cell Mol. Biol. 2013, 48:448-455.
-
(2013)
Am. J. Respir. Cell Mol. Biol.
, vol.48
, pp. 448-455
-
-
Leppäranta, O.1
-
27
-
-
79955563790
-
Organic synthesis toward small-molecule probes and drugs
-
Schreiber S.L. Organic synthesis toward small-molecule probes and drugs. Proc. Natl. Acad. Sci. U.S.A. 2011, 108:6699-6702.
-
(2011)
Proc. Natl. Acad. Sci. U.S.A.
, vol.108
, pp. 6699-6702
-
-
Schreiber, S.L.1
-
28
-
-
84867350005
-
Identification of novel 2-((1-(benzyl(2-hydroxy-2-phenylethyl)amino)-1-oxo-3-phenylpropan-2-yl)carbamoyl) benzoic acid analogues as BMP-2 stimulators
-
Balaramnavar V.M., et al. Identification of novel 2-((1-(benzyl(2-hydroxy-2-phenylethyl)amino)-1-oxo-3-phenylpropan-2-yl)carbamoyl) benzoic acid analogues as BMP-2 stimulators. J. Med. Chem. 2012, 55:8248-8259.
-
(2012)
J. Med. Chem.
, vol.55
, pp. 8248-8259
-
-
Balaramnavar, V.M.1
-
29
-
-
84869386452
-
Reawakening atlas: chemical approaches to repair or replace dysfunctional musculature
-
Jung D.W., Williams D.R. Reawakening atlas: chemical approaches to repair or replace dysfunctional musculature. ACS Chem. Biol. 2012, 7:1773-1790.
-
(2012)
ACS Chem. Biol.
, vol.7
, pp. 1773-1790
-
-
Jung, D.W.1
Williams, D.R.2
-
30
-
-
84873956758
-
Crosslinking strategies facilitate tunable structural properties of fibrin microthreads
-
Grasman J.M., et al. Crosslinking strategies facilitate tunable structural properties of fibrin microthreads. Acta Biomater. 2012, 8:4020-4230.
-
(2012)
Acta Biomater.
, vol.8
, pp. 4020-4230
-
-
Grasman, J.M.1
-
31
-
-
84887395504
-
Bone morphogenetic proteins for bone regeneration and their alternatives
-
Laurencin C.T., Lo K.W. Bone morphogenetic proteins for bone regeneration and their alternatives. Curr. Pharm. Des. 2013, 19:3353.
-
(2013)
Curr. Pharm. Des.
, vol.19
, pp. 3353
-
-
Laurencin, C.T.1
Lo, K.W.2
-
32
-
-
84882367798
-
Angiotensin II inhibits satellite cell proliferation and prevents skeletal muscle regeneration
-
Yoshida T., et al. Angiotensin II inhibits satellite cell proliferation and prevents skeletal muscle regeneration. J. Biol. Chem. 2013, 288:23823-23832.
-
(2013)
J. Biol. Chem.
, vol.288
, pp. 23823-23832
-
-
Yoshida, T.1
-
33
-
-
84866160682
-
Sphingosine kinase/sphingosine 1-phosphate axis: a new player for insulin-like growth factor-1-induced myoblast differentiation
-
Bernacchioni C., et al. Sphingosine kinase/sphingosine 1-phosphate axis: a new player for insulin-like growth factor-1-induced myoblast differentiation. Skelet. Muscle 2012, 2:15.
-
(2012)
Skelet. Muscle
, vol.2
, pp. 15
-
-
Bernacchioni, C.1
-
34
-
-
77749264598
-
Sphingosine 1-phosphate signaling is involved in skeletal muscle regeneration
-
Danieli-Betto D., et al. Sphingosine 1-phosphate signaling is involved in skeletal muscle regeneration. Am. J. Physiol. Cell Physiol. 2010, 298:C550-C558.
-
(2010)
Am. J. Physiol. Cell Physiol.
, vol.298
-
-
Danieli-Betto, D.1
-
35
-
-
84880886286
-
Increased sphingosine-1-phosphate improves muscle regeneration in acutely injured mdx mice
-
Ieronimakis N., et al. Increased sphingosine-1-phosphate improves muscle regeneration in acutely injured mdx mice. Skelet. Muscle 2013, 3:20.
-
(2013)
Skelet. Muscle
, vol.3
, pp. 20
-
-
Ieronimakis, N.1
-
36
-
-
70449512215
-
Retinoic acid enhances skeletal muscle progenitor formation and bypasses inhibition by bone morphogenetic protein 4 but not dominant negative beta-catenin
-
Kennedy K.A., et al. Retinoic acid enhances skeletal muscle progenitor formation and bypasses inhibition by bone morphogenetic protein 4 but not dominant negative beta-catenin. BMC Biol. 2009, 7:67.
-
(2009)
BMC Biol.
, vol.7
, pp. 67
-
-
Kennedy, K.A.1
-
37
-
-
84860138073
-
Small molecules that recapitulate the early steps of urodele amphibian limb regeneration and confer multipotency
-
Kim W.H., et al. Small molecules that recapitulate the early steps of urodele amphibian limb regeneration and confer multipotency. ACS Chem. Biol. 2012, 7:732-743.
-
(2012)
ACS Chem. Biol.
, vol.7
, pp. 732-743
-
-
Kim, W.H.1
-
38
-
-
84857770165
-
Current clinical therapies for cartilage repair, their limitation and the role of stem cells
-
Dhinsa B.S., Adesida A.B. Current clinical therapies for cartilage repair, their limitation and the role of stem cells. Curr. Stem Cell Res. Ther. 2012, 7:143-148.
-
(2012)
Curr. Stem Cell Res. Ther.
, vol.7
, pp. 143-148
-
-
Dhinsa, B.S.1
Adesida, A.B.2
-
39
-
-
84885512597
-
Articular cartilage repair
-
AAOS, Rosemont, IL, T.A. Einhorn, R.J.O. Keefe, J.A. Buckwalter (Eds.)
-
O'Driscoll S.W., Saris D.B.F. Articular cartilage repair. Orthopaedic Basic Science 2007, AAOS, Rosemont, IL. T.A. Einhorn, R.J.O. Keefe, J.A. Buckwalter (Eds.).
-
(2007)
Orthopaedic Basic Science
-
-
O'Driscoll, S.W.1
Saris, D.B.F.2
-
41
-
-
77950659332
-
Articular cartilage and subchondral bone in the pathogenesis of osteoarthritis
-
Goldring M.B., Goldring S.R. Articular cartilage and subchondral bone in the pathogenesis of osteoarthritis. Ann. N. Y. Acad. Sci. 2010, 1192:230-237.
-
(2010)
Ann. N. Y. Acad. Sci.
, vol.1192
, pp. 230-237
-
-
Goldring, M.B.1
Goldring, S.R.2
-
42
-
-
77956875270
-
Inhibition of osteoclasts prevents cartilage loss and pain in a rat model of degenerative joint disease
-
Strassle B.W., et al. Inhibition of osteoclasts prevents cartilage loss and pain in a rat model of degenerative joint disease. Osteoarthritis Cartilage 2010, 18:1319-1328.
-
(2010)
Osteoarthritis Cartilage
, vol.18
, pp. 1319-1328
-
-
Strassle, B.W.1
-
43
-
-
77955438432
-
Inhibition of bone resorption blunts osteoarthritis in mice with high bone remodelling
-
Kadri A., et al. Inhibition of bone resorption blunts osteoarthritis in mice with high bone remodelling. Ann. Rheum. Dis. 2010, 69:1533-1538.
-
(2010)
Ann. Rheum. Dis.
, vol.69
, pp. 1533-1538
-
-
Kadri, A.1
-
44
-
-
79959277624
-
Tiludronate treatment improves structural changes and symptoms of osteoarthritis in the canine anterior cruciate ligament model
-
Moreau M., et al. Tiludronate treatment improves structural changes and symptoms of osteoarthritis in the canine anterior cruciate ligament model. Arthritis Res. Ther. 2011, 13:R98.
-
(2011)
Arthritis Res. Ther.
, vol.13
-
-
Moreau, M.1
-
45
-
-
84455202518
-
Subchondral bone as a key target for osteoarthritis treatment
-
Castañeda S., et al. Subchondral bone as a key target for osteoarthritis treatment. Biochem. Pharmacol. 2012, 83:315-323.
-
(2012)
Biochem. Pharmacol.
, vol.83
, pp. 315-323
-
-
Castañeda, S.1
-
46
-
-
1842632402
-
The role of subchondral bone remodeling in osteoarthritis: reduction of cartilage degeneration and prevention of osteophyte formation by alendronate in the rat anterior cruciate ligament transection model
-
Hayami T., et al. The role of subchondral bone remodeling in osteoarthritis: reduction of cartilage degeneration and prevention of osteophyte formation by alendronate in the rat anterior cruciate ligament transection model. Arthritis Rheum. 2004, 50:1193-1206.
-
(2004)
Arthritis Rheum.
, vol.50
, pp. 1193-1206
-
-
Hayami, T.1
-
47
-
-
1542286076
-
The inhibition of subchondral bone resorption in the early phase of experimental dog osteoarthritis by licofelone is associated with a reduction in the synthesis of MMP-13 and cathepsin K
-
Pelletier J.P., et al. The inhibition of subchondral bone resorption in the early phase of experimental dog osteoarthritis by licofelone is associated with a reduction in the synthesis of MMP-13 and cathepsin K. Bone 2004, 34:527-538.
-
(2004)
Bone
, vol.34
, pp. 527-538
-
-
Pelletier, J.P.1
-
48
-
-
84875153784
-
Effect of treatment with the cathepsin-k inhibitor, balicatib, on cartilage volume and biochemical markers of bone and cartilage degradation in patients with painful knee osteoarthritis
-
Manicourt D., et al. Effect of treatment with the cathepsin-k inhibitor, balicatib, on cartilage volume and biochemical markers of bone and cartilage degradation in patients with painful knee osteoarthritis. Osteoarthritis Cartilage 2007, 15:C130.
-
(2007)
Osteoarthritis Cartilage
, vol.15
-
-
Manicourt, D.1
-
49
-
-
67449128722
-
Protective effects of licofelone, a 5-lipoxygenase and cyclo-oxygenase inhibitor, versus naproxen on cartilage loss in knee osteoarthritis: a first multicentre clinical trial using quantitative MRI
-
Raynauld J.P., et al. Protective effects of licofelone, a 5-lipoxygenase and cyclo-oxygenase inhibitor, versus naproxen on cartilage loss in knee osteoarthritis: a first multicentre clinical trial using quantitative MRI. Ann. Rheumat. Dis. 2009, 68:938-947.
-
(2009)
Ann. Rheumat. Dis.
, vol.68
, pp. 938-947
-
-
Raynauld, J.P.1
-
50
-
-
0035143316
-
Strontium ranelate increases cartilage matrix formation
-
Henrotin Y., et al. Strontium ranelate increases cartilage matrix formation. J. Bone Miner. Res. 2001, 16:299-308.
-
(2001)
J. Bone Miner. Res.
, vol.16
, pp. 299-308
-
-
Henrotin, Y.1
-
51
-
-
84872070437
-
Strontium ranelate reduces the progression of experimental dog osteoarthritis by inhibiting the expression of key proteases in cartilage and of IL-1beta in the synovium
-
Pelletier J.P., et al. Strontium ranelate reduces the progression of experimental dog osteoarthritis by inhibiting the expression of key proteases in cartilage and of IL-1beta in the synovium. Ann. Rheum. Dis. 2013, 72:250-257.
-
(2013)
Ann. Rheum. Dis.
, vol.72
, pp. 250-257
-
-
Pelletier, J.P.1
-
52
-
-
84874606888
-
Strontium ranelate reduces cartilage degeneration and subchondral bone remodeling in rat osteoarthritis model
-
Yu D.G., et al. Strontium ranelate reduces cartilage degeneration and subchondral bone remodeling in rat osteoarthritis model. Acta Pharmacol. Sin. 2013, 34:393-402.
-
(2013)
Acta Pharmacol. Sin.
, vol.34
, pp. 393-402
-
-
Yu, D.G.1
-
53
-
-
33845191832
-
Strontium ranelate reduces the urinary level of cartilage degradation biomarker CTX-II in postmenopausal women
-
Alexandersen P., et al. Strontium ranelate reduces the urinary level of cartilage degradation biomarker CTX-II in postmenopausal women. Bone 2007, 40:218-222.
-
(2007)
Bone
, vol.40
, pp. 218-222
-
-
Alexandersen, P.1
-
54
-
-
79952792784
-
Strontium ranelate effect in postmenopausal women with different clinical levels of osteoarthritis
-
Alexandersen P., et al. Strontium ranelate effect in postmenopausal women with different clinical levels of osteoarthritis. Climacteric 2011, 14:236-243.
-
(2011)
Climacteric
, vol.14
, pp. 236-243
-
-
Alexandersen, P.1
-
55
-
-
84893581176
-
Autograft versus nonirradiated allograft tissue for anterior cruciate ligament reconstruction: a systematic review
-
Mariscalco M.W., et al. Autograft versus nonirradiated allograft tissue for anterior cruciate ligament reconstruction: a systematic review. Am. J. Sports Med. 2013, 10.1177/0363546513497566.
-
(2013)
Am. J. Sports Med.
-
-
Mariscalco, M.W.1
-
56
-
-
85047690810
-
Anterior cruciate ligament reconstruction: which graft is bestα
-
Sherman O.H., Banffy M.B. Anterior cruciate ligament reconstruction: which graft is bestα. Arthroscopy 2004, 20:974-980.
-
(2004)
Arthroscopy
, vol.20
, pp. 974-980
-
-
Sherman, O.H.1
Banffy, M.B.2
-
57
-
-
84887135964
-
Metalloproteases and tendinopathy
-
Del Buono A., et al. Metalloproteases and tendinopathy. Muscles Ligaments Tendons J. 2013, 3:51-57.
-
(2013)
Muscles Ligaments Tendons J.
, vol.3
, pp. 51-57
-
-
Del Buono, A.1
-
58
-
-
27544462442
-
Enhancement of tendon-bone healing of anterior cruciate ligament grafts by blockage of matrix metalloproteinases
-
Demirag B., et al. Enhancement of tendon-bone healing of anterior cruciate ligament grafts by blockage of matrix metalloproteinases. J. Bone Joint Surg. 2005, 87:2401-2410.
-
(2005)
J. Bone Joint Surg.
, vol.87
, pp. 2401-2410
-
-
Demirag, B.1
-
59
-
-
84878386693
-
Alendronate reduced peri-tunnel bone loss and enhanced tendon graft to bone tunnel healing in anterior cruciate ligament reconstruction
-
Lui P.P., et al. Alendronate reduced peri-tunnel bone loss and enhanced tendon graft to bone tunnel healing in anterior cruciate ligament reconstruction. Eur. Cells Mater. 2013, 25:78-96.
-
(2013)
Eur. Cells Mater.
, vol.25
, pp. 78-96
-
-
Lui, P.P.1
-
60
-
-
84886296304
-
Local administration of alendronate reduced peri-tunnel bone loss and promoted graft-bone tunnel healing with minimal systemic effect on bone in contralateral knee
-
Lui P.P., et al. Local administration of alendronate reduced peri-tunnel bone loss and promoted graft-bone tunnel healing with minimal systemic effect on bone in contralateral knee. J. Orthop. Res. 2013, 31:1897-1906.
-
(2013)
J. Orthop. Res.
, vol.31
, pp. 1897-1906
-
-
Lui, P.P.1
-
61
-
-
34047201901
-
Alendronate prevents bone loss and improves tendon-to-bone repair strength in a canine model
-
Thomopoulos S., et al. Alendronate prevents bone loss and improves tendon-to-bone repair strength in a canine model. J. Orthop. Res. 2007, 25:473-479.
-
(2007)
J. Orthop. Res.
, vol.25
, pp. 473-479
-
-
Thomopoulos, S.1
-
62
-
-
40349091848
-
The role of macrophages in early healing of a tendon graft in a bone tunnel
-
Hays P.L., et al. The role of macrophages in early healing of a tendon graft in a bone tunnel. J. Bone Joint Surg. 2008, 90:565-579.
-
(2008)
J. Bone Joint Surg.
, vol.90
, pp. 565-579
-
-
Hays, P.L.1
-
63
-
-
70349148159
-
Differential expression of matrix metalloproteinases and tissue inhibitors of metalloproteinases in anterior cruciate ligament and medial collateral ligament fibroblasts after a mechanical injury: involvement of the p65 subunit of NF-kappaB
-
Tang Z., et al. Differential expression of matrix metalloproteinases and tissue inhibitors of metalloproteinases in anterior cruciate ligament and medial collateral ligament fibroblasts after a mechanical injury: involvement of the p65 subunit of NF-kappaB. Wound Repair Regen. 2009, 17:709-716.
-
(2009)
Wound Repair Regen.
, vol.17
, pp. 709-716
-
-
Tang, Z.1
-
64
-
-
79955689544
-
TGF-β1 promoted MMP-2 mediated wound healing of anterior cruciate ligament fibroblasts through NF-κB
-
Wang Y., et al. TGF-β1 promoted MMP-2 mediated wound healing of anterior cruciate ligament fibroblasts through NF-κB. Connect. Tissue Res. 2011, 52:218-225.
-
(2011)
Connect. Tissue Res.
, vol.52
, pp. 218-225
-
-
Wang, Y.1
-
65
-
-
34547662965
-
Peripheral regerenation
-
Chen Z.L., et al. Peripheral regerenation. Annu. Rev. Neurosci. 2007, 30:209-233.
-
(2007)
Annu. Rev. Neurosci.
, vol.30
, pp. 209-233
-
-
Chen, Z.L.1
-
67
-
-
67649399222
-
Polysialic acid glycomimetics promote myelination and functional recovery after peripheral nerve injury in mice
-
Mehanna A., et al. Polysialic acid glycomimetics promote myelination and functional recovery after peripheral nerve injury in mice. Brain 2009, 132:1449-1462.
-
(2009)
Brain
, vol.132
, pp. 1449-1462
-
-
Mehanna, A.1
-
68
-
-
81155137857
-
Neural cell type-specific responses to glycomimetic functionalized collagen
-
Masand S.N., et al. Neural cell type-specific responses to glycomimetic functionalized collagen. Biomaterials 2012, 33:790-797.
-
(2012)
Biomaterials
, vol.33
, pp. 790-797
-
-
Masand, S.N.1
-
69
-
-
84866143296
-
The effect of glycomimetic functionalized collagen on peripheral nerve repair
-
Masand S.N., et al. The effect of glycomimetic functionalized collagen on peripheral nerve repair. Biomaterials 2012, 33:8353-8362.
-
(2012)
Biomaterials
, vol.33
, pp. 8353-8362
-
-
Masand, S.N.1
-
70
-
-
84890803714
-
Nonyloxytryptamine mimics polysialic acid and modulates neuronal and glial functions in cell culture
-
Loers G., et al. Nonyloxytryptamine mimics polysialic acid and modulates neuronal and glial functions in cell culture. J. Neurochem. 2013, 10.1111/jnc.12408.
-
(2013)
J. Neurochem.
-
-
Loers, G.1
-
71
-
-
77953786885
-
Db-Cyclic adenosine monophosphate promotes axon regeneration and motor function recovery in cerebral ischemia-reperfusion rats
-
Niu L., et al. db-Cyclic adenosine monophosphate promotes axon regeneration and motor function recovery in cerebral ischemia-reperfusion rats. Neurol. India 2010, 58:195-200.
-
(2010)
Neurol. India
, vol.58
, pp. 195-200
-
-
Niu, L.1
-
72
-
-
79959726079
-
Effects of dibutyryl cyclic-AMP on survival and neuronal differentiation of neural stem/progenitor cells transplanted into spinal cord injured rats
-
Kim H., et al. Effects of dibutyryl cyclic-AMP on survival and neuronal differentiation of neural stem/progenitor cells transplanted into spinal cord injured rats. PLoS ONE 2011, 6:e21744.
-
(2011)
PLoS ONE
, vol.6
-
-
Kim, H.1
-
73
-
-
36249031068
-
Recognizing and exploiting differences between RNAi and small-molecule inhibitors
-
Weiss W.A., et al. Recognizing and exploiting differences between RNAi and small-molecule inhibitors. Nat. Chem. Biol. 2007, 3:739-744.
-
(2007)
Nat. Chem. Biol.
, vol.3
, pp. 739-744
-
-
Weiss, W.A.1
-
74
-
-
79960238966
-
Network neighbors of drug targets contribute to drug side-effect similarity
-
Brouwers L., et al. Network neighbors of drug targets contribute to drug side-effect similarity. PLoS ONE 2011, 6:e22187.
-
(2011)
PLoS ONE
, vol.6
-
-
Brouwers, L.1
-
75
-
-
70249124606
-
Controlled growth factor delivery for tissue engineering
-
Tayalia P., Mooney D.J. Controlled growth factor delivery for tissue engineering. Adv. Mater. 2009, 21:3269-3285.
-
(2009)
Adv. Mater.
, vol.21
, pp. 3269-3285
-
-
Tayalia, P.1
Mooney, D.J.2
-
76
-
-
85027952550
-
One-day treatment of small molecule 8-bromo-cyclic AMP analogue induces cell-based VEGF production for in vitro angiogenesis and osteoblastic differentiation
-
Lo K-W.H., et al. One-day treatment of small molecule 8-bromo-cyclic AMP analogue induces cell-based VEGF production for in vitro angiogenesis and osteoblastic differentiation. J. Tissue Eng. Regen. Med. 2013, 10.1002/term.1839.
-
(2013)
J. Tissue Eng. Regen. Med.
-
-
Lo, K.-W.H.1
-
77
-
-
77953311260
-
Small molecule screening in zebrafish: an in vivo approach to identifying new chemical tools and drug leads
-
Taylor K.L., et al. Small molecule screening in zebrafish: an in vivo approach to identifying new chemical tools and drug leads. Cell Commun. Signal. 2010, 8:11.
-
(2010)
Cell Commun. Signal.
, vol.8
, pp. 11
-
-
Taylor, K.L.1
-
78
-
-
79251511501
-
Identification of direct protein targets of small molecules
-
Lomenick B., et al. Identification of direct protein targets of small molecules. ACS Chem. Biol. 2011, 6:34-46.
-
(2011)
ACS Chem. Biol.
, vol.6
, pp. 34-46
-
-
Lomenick, B.1
-
79
-
-
73349093728
-
High-performance drug discovery: computational screening by combining docking and molecular dynamics simulations
-
Okimoto N., et al. High-performance drug discovery: computational screening by combining docking and molecular dynamics simulations. PLoS Comput. Biol. 2009, 5:e1000528.
-
(2009)
PLoS Comput. Biol.
, vol.5
-
-
Okimoto, N.1
-
80
-
-
84858959483
-
Nanostructured polymeric scaffolds for orthopaedic regenerative engineering
-
Deng M., et al. Nanostructured polymeric scaffolds for orthopaedic regenerative engineering. IEEE Trans. Nanobioscience 2012, 11:3-14.
-
(2012)
IEEE Trans. Nanobioscience
, vol.11
, pp. 3-14
-
-
Deng, M.1
-
81
-
-
0038480134
-
Looking back to the embryo: defining transcriptional networks in adult myogenesis
-
Parker M.H., et al. Looking back to the embryo: defining transcriptional networks in adult myogenesis. Nat. Rev. 2003, 4:497-507.
-
(2003)
Nat. Rev.
, vol.4
, pp. 497-507
-
-
Parker, M.H.1
-
82
-
-
27744588940
-
Mechanism of osteogenic induction by FK506 via BMP/Smad pathways
-
Kugimiya F., et al. Mechanism of osteogenic induction by FK506 via BMP/Smad pathways. Biochem. Biophys. Res. Commun. 2005, 338:872-879.
-
(2005)
Biochem. Biophys. Res. Commun.
, vol.338
, pp. 872-879
-
-
Kugimiya, F.1
|