Purmorphamine induces osteogenesis by activation of the Hedgehog signaling pathway

Chemistry and Biology

Volumn 11, Issue 9, 2004, Pages 1229-1238

  Wu, Xu ^a   Walker, John ^b   Zhang, Jie ^b   Ding, Sheng ^a   Schultz, Peter G ^a,b  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b GENOMICS INSTITUTE OF THE NOVARTIS RESEARCH FOUNDATION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALKALINE PHOSPHATASE; BONE MORPHOGENETIC PROTEIN; BONE MORPHOGENETIC PROTEIN 4; CYCLOPAMINE; FORSKOLIN; MORPHOLINE DERIVATIVE; PURINE DERIVATIVE; PURMORPHAMINE; SONIC HEDGEHOG PROTEIN; TRANSACTIVATOR PROTEIN; VERATRUM ALKALOID;

ANIMAL; ARTICLE; BONE DEVELOPMENT; C3H MOUSE; CLUSTER ANALYSIS; DNA MICROARRAY; DRUG ANTAGONISM; DRUG EFFECT; FIBROBLAST; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; METABOLISM; MOUSE; PHYSIOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION;

ALKALINE PHOSPHATASE; ANIMALS; BONE MORPHOGENETIC PROTEINS; CLUSTER ANALYSIS; FIBROBLASTS; FORSKOLIN; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HEDGEHOG PROTEINS; MICE; MICE, INBRED C3H; MORPHOLINES; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; OSTEOGENESIS; PURINES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TRANS-ACTIVATORS; TRANSCRIPTION, GENETIC; VERATRUM ALKALOIDS;

ERINACEIDAE;

EID: 4644250693     PISSN: 10745521     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chembiol.2004.06.010     Document Type: Article

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