Development of high-throughput screening system for osteogenic drugs using a cell-based sensor

Biochemical and Biophysical Research Communications

Volumn 376, Issue 2, 2008, Pages 375-379

  Hojo, Hironori ^a,b   Igawa, Kazuyo ^b   Ohba, Shinsuke ^b   Yano, Fumiko ^b   Nakajima, Keiji ^b   Komiyama, Yuske ^b   Ikeda, Toshiyuki ^b   Lichtler, Alexander C ^c   Woo, Je Tae ^b   Yonezawa, Takayuki ^b   Takato, Tsuyoshi ^b   Chung, Ung il ^b  

^a JAPAN SOCIETY FOR THE PROMOTION OF SCIENCE   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

^c UNIVERSITY OF CONNECTICUT HEALTH CENTER   (United States)

Author keywords

Col1a1GFP MC3T3E1; Osteoblast; Screening system; Small compounds

Indexed keywords

ALKALINE PHOSPHATASE; BONE MORPHOGENETIC PROTEIN 2; GLABRISOFLAVONE; GREEN FLUORESCENT PROTEIN; GROWTH FACTOR; ISOFLAVONE DERIVATIVE; MESSENGER RNA; OSTEOCALCIN; OSTEOGENIC AGENT; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BIOSENSOR; BONE DEVELOPMENT; CELL STRAIN 3T3; HIGH THROUGHPUT SCREENING; MOUSE; NONHUMAN; OSTEOBLAST; PRIORITY JOURNAL; REPORTER GENE;

ALKALINE PHOSPHATASE; ANIMALS; BIOSENSING TECHNIQUES; BONE MORPHOGENETIC PROTEINS; CELL LINE; COLLAGEN TYPE I; DRUG EVALUATION, PRECLINICAL; FLUORESCENCE; GENES, REPORTER; GREEN FLUORESCENT PROTEINS; ISOFLAVONES; MICE; OSTEOBLASTS; OSTEOCALCIN; OSTEOGENESIS; OSTEOPOROSIS; RATS; TRANSFORMING GROWTH FACTOR BETA;

RATTUS;

EID: 52949105725     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2008.08.167     Document Type: Article

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