Small molecule inducers of angiogenesis for tissue engineering

Tissue Engineering

Volumn 12, Issue 7, 2006, Pages 1903-1913

  Wieghaus, Kristen A ^a   Capitosti, Scott M ^b   Anderson, Christopher R ^a   Price, Richard J ^a   Blackman, Brett R ^a   Brown, Milton L ^b,c   Botchwey, Edward A ^a,b,c  

^a University of Virginia   (United States)

^b UNIVERSITY OF VIRGINIA   (United States)

^c UNIVERSITY OF VIRGINIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOMEDICAL ENGINEERING; CELL CULTURE; GROWTH KINETICS; MOLECULAR BIOLOGY; NUTRITION; PATIENT TREATMENT;

ANGIOGENESIS; DRUG DELIVERY; GROWTH FACTOR; TISSUE ENGINEERING;

TISSUE;

SMALL MOLECULE TRANSPORT AGENT;

ACIDITY; ANGIOGENESIS; ANIMAL CELL; ARTICLE; BONE GRAFT; CELL DEATH; CELL PROLIFERATION; CELL SURVIVAL; DRUG TARGETING; ENDOTHELIUM CELL; MICROVASCULATURE; NEOVASCULARIZATION (PATHOLOGY); NONHUMAN; PRIORITY JOURNAL; QUALITATIVE ANALYSIS; TISSUE ENGINEERING; TISSUE REPAIR; VASCULAR ENDOTHELIUM; WOUND HEALING;

ANGIOGENESIS INDUCING AGENTS; ANIMALS; BIOPROSTHESIS; CELL PROLIFERATION; CELLS, CULTURED; ENDOTHELIAL CELLS; FEMALE; HETEROCYCLIC COMPOUNDS, 3-RING; HUMANS; INDOLES; NEOVASCULARIZATION, PHYSIOLOGIC; RATS; RATS, SPRAGUE-DAWLEY; TIME FACTORS; TISSUE ENGINEERING; WOUND HEALING;

EID: 33746729750     PISSN: 10763279     EISSN: None     Source Type: Journal    
DOI: 10.1089/ten.2006.12.1903     Document Type: Article

References (56)

1. Collin-Osdoby P. Role of vascular endothelial cells in bone biology. J. Cell Biochem. 55, 304, 1994.
2. Carano RA, Filvaroff EH. Angiogenesis and bone repair. Drug Discov. Today 8, 980, 2003.
3. Kaigler D, Krebsbach PH, Polverini PJ, Mooney DJ. Role of vascular endothelial growth factor in bone marrow stromal cell modulation of endothelial cells. Tissue Eng. 9, 95, 2003.
4. Murphy WL, Simmons CA, Kaigler D, Mooney DJ. Bone regeneration via a mineral substrate and induced angiogenesis. J. Dent. Res. 83, 204, 2004.
5. Weiland AJ, Phillips TW, Randolph MA. Bone grafts: a radiologic, histologic, and biomechanical model comparing autografts, allografts, and free vascularized bone grafts. Plast. Reconstr. Surg. 74, 368, 1984.
6. Pelissier P, Villars F, Mathoulin-Pelissier S, Bareille R, Lafage-Proust MH, Vilamitjana-Amedee J. Influences of vascularization and osteogenic cells on heterotopic bone formation within a madreporic ceramic in rats. Plast. Reconstr. Surg. 111, 1932, 2003.
7. Carmeliet P, Jain RK. Angiogenesis in cancer and other diseases. Nature 407, 249, 2000.
8. Colton CK. Implantable biohybrid artificial organs. Cell Transplant. 4, 415, 1995.
9. Wong RW, Rabie AB. Early healing pattern of statin-induced osteogenesis. Br. J. Oral Maxillofac. Surg. 43, 46, 2005.
10. Kelpke SS, Zinn KR, Rue LW, Thompson JA. Site-specific delivery of acidic fibroblast growth factor stimulates angiogenic and osteogenic responses in vivo. J. Biomed. Mater. Res. A 71, 316, 2004.
11. Yang C, Yang SH, Du JY, Li J, Xu WH, Xiong YF. Basic fibroblast growth factor gene transfection to enhance the repair of avascular necrosis of the femoral head. Chin. Med. Sci. J. 19, 111, 2004.
12. Carmeliet P. VEGF gene therapy: stimulating angiogenesis or angioma-genesis? Nat. Med. 6, 1102, 2000.
13. Ferrara N, Alitalo K. Clinical applications of angiogenic growth factors and their inhibitors. Nat. Med. 5, 1359, 1999.
14. Yancopoulos GD, Davis S, Gale NW, Rudge JS, Wiegand SJ, Holash J. Vascular-specific growth factors and blood vessel formation. Nature 407, 242, 2000.
15. Gu F, Amsden B, Neufeld R. Sustained delivery of vascular endothelial growth factor with alginate beads. J. Control Release 96, 463, 2004.
16. Zisch AH, Lutolf MP, Ehrbar M, Raeber GP, Rizzi SC, Davies N, Schmokel H, Bezuidenhout D, Djonov V, Zilla P, Hubbell JA. Cell-demanded release of VEGF from synthetic, biointeractive cell ingrowth matrices for vascularized tissue growth. FASEB J. 17, 2260, 2003.
17. Cleland JL, Duenas ET, Park A, Daugherty A, Kahn J, Kowalski J, Cuthbertson A. Development of poly-(D,L-lactidecoglycolide) microsphere formulations containing recombinant human vascular endothelial growth factor to promote local angiogenesis. J. Control Release 72, 13, 2001.
18. Smith MK, Peters MC, Richardson TP, Garbern JC, Mooney DJ. Locally enhanced angiogenesis promotes transplanted cell survival. Tissue Eng. 10, 63, 2004.
19. Freedman SB, Isner JM. Therapeutic angiogenesis for coronary artery disease. Ann. Intern. Med. 136, 54, 2002.
20. Carmeliet P. Mechanisms of angiogenesis and arteriogenesis. Nat. Med. 6, 389, 2000.
21. Nomi M, Atala A, Coppi PD, Soker S. Principals of neovascularization for tissue engineering. Mol. Aspects Med. 23, 463, 2002.
22. van de WM, Hennink WE, Jiskoot W. Protein instability in poly(lactic-co-glycolic acid) microparticles. Pharm. Res. 17, 1159, 2000.
23. Fu K, Klibanov AM, Langer R. Protein stability in controlled-release systems. Nat. Biotechnol. 18, 24, 2000.
24. Shao PG, Bailey LC. Stabilization of pH-induced degradation of porcine insulin in biodegradable polyester microspheres. Pharm. Dev. Technol. 4, 633, 1999.
25. Zhu G, Mallery SR, Schwendeman SP. Stabilization of proteins encapsulated in injectable poly (lactide- co-glycolide). Nat. Biotechnol. 18, 52, 2000.
26. Rothen-Weinhold A, Oudry N, Schwach-Abdellaoui K, Frutiger-Hughes S, Hughes GJ, Jeannerat D, Burger U, Besseghir K, Gurny R. Formation of peptide impurities in polyester matrices during implant manufacturing. Eur. J. Pharm. Biopharm. 49, 253, 2000.
27. Lucke A, Kiermaier J, Gopferich A. Peptide acylation by poly(alpha-hydroxy esters). Pharm. Res. 19, 175, 2002.
28. Bartus RT, Tracy MA, Emerich DF, Zale SE. Sustained delivery of proteins for novel therapeutic agents. Science 281, 1161, 1998.
29. Lee RJ, Springer ML, Blanco-Bose WE, Shaw R, Ursell PC, Blau HM. VEGF gene delivery to myocardium: deleterious effects of unregulated expression. Circulation 102, 898, 2000.
30. Springer ML, Chen AS, Kraft PE, Bednarski M, Blau HM. VEGF gene delivery to muscle: potential role for vasculogenesis in adults. Mol. Cell 2, 549, 1998.
31. Brennen WN, Cooper CR, Capitosti S, Brown ML, Sikes RA. Thalidomide and analogues: current proposed mechanisms and therapeutic usage. Clin. Prostate Cancer 3, 54, 2004.
32. Capitosti SM, Hansen TP, Brown ML. Thalidomide analogues demonstrate dual inhibition of both angiogenesis and prostate cancer. Bioorg. Med. Chem. 12, 327, 2004.
33. Schubert H, Ruehberg B, Fiedrich G. J. Synthesis of 4,5-trimethylene imidazole. fuer Prakt. Chem. (Germany) 32, 249, 1966.
34. Herve MA, Buteau-Lozano H, Mourah S, Calvo F, Perrot-Applanat M. VEGF189 stimulates endothelial cells proliferation and migration in vitro and up-regulates the expression of Flk-1/KDR mRNA. Exp. Cell Res. 309, 24, 2005.
35. Sun XT, Ding YT, Yan XG, Wu LY, Li Q, Cheng N, Qiu YD, Zhang MY. Angiogenic synergistic effect of basic fibroblast growth factor and vascular endothelial growth factor in an in vitro quantitative microcarrier-based three-dimensional fibrin angiogenesis system. World J. Gastroenterol. 10, 2524, 2004.
36. Chen J, Wang X, Zhu J, Shang Y, Guo S, Sun J. Effects of Ginkgo biloba extract on number and activity of endothelial progenitor cells from peripheral blood. J. Cardiovasc. Pharmacol. 43, 347, 2004.
37. Sun J, Blaskovich MA, Jain RK, Delarue F, Paris D, Brem S, Wotoczek-Obadia M, Lin Q, Coppola D, Choi K, Mullan M, Hamilton AD, Sebti SM. Blocking angiogenesis and tumorigenesis with GFA-116, a synthetic molecule that inhibits binding of vascular endothelial growth factor to its receptor. Cancer Res. 64, 3586, 2004.
38. van der Schaft DW, Dings RP, de Lussanet QG, van Eijk LI, Nap AW, Beets-Tan RG, Bouma-Ter Steege JC, Wagstaff J, Mayo KH, Griffioen AW. The designer anti-angiogenic peptide anginex targets tumor endothelial cells and inhibits tumor growth in animal models. FASEB J. 16, 1991, 2002.
39. McGrath JL, Osborn EA, Tardy YS, Dewey CF, Jr., Hartwig JH. Regulation of the actin cycle in vivo by actin filament severing. Proc. Natl. Acad. Sci. U. S. A. 97, 6532, 2000.
40. Maffulli N, Ewen SW, Waterston SW, Reaper J, Barrass V. Tenocytes from ruptured and tendinopathic Achilles tendons produce greater quantities of type III collagen than tenocytes from normal Achilles tendons. An in vitro model of human tendon healing. Am. J. Sports Med. 28, 499, 2000.
41. Anderson CR, Ponce AM, Price RJ. Immunohistochemical identification of an extracellular matrix scaffold that microguides capillary sprouting in vivo. J. Histochem. Cytochem. 52, 1063, 2004.
42. Anderson CR, Ponce AM, Price RJ. Absence of OX-43 antigen expression in invasive capillary sprouts: identification of a capillary sprout-specific endothelial phenotype. Am. J. Physiol Heart Circ. Physiol. 286, H346, 2004.
43. Hansen-Smith FM, Joswiak GR, Baustert JL. Regional differences in spontaneously occurring angiogenesis in the adult rat mesentery. Microvasc. Res. 47, 369, 1994.
44. Ponce AM, Price RJ. Angiogenic stimulus determines the positioning of pericytes within capillary sprouts in vivo. Microvasc. Res. 65, 45, 2003.
45. Ishaug SL, Crane GM, Miller MJ, Yasko AW, Yaszemski MJ, Mikos AG. Bone formation by three-dimensional stromal osteoblast culture in biodegradable polymer scaffolds. J. Biomed. Mater. Res. 36, 17, 1997.
46. Botchwey EA, Pollack SR, Levine EM, Laurencin CT. Bone tissue engineering in a rotating bioreactor using a microcarrier matrix system. J. Biomed. Mater. Res. 55, 242, 2001.
47. Botchwey EA, Dupree MA, Pollack SR, Levine EM, Laurencin CT. Tissue engineered bone: measurement of nutrient transport in three-dimensional matrices. J. Biomed. Mater. Res. A 67, 357, 2003.
48. Botchwey EA, Pollack SR, Levine EM, Johnston ED, Laurencin CT. Quantitative analysis of three-dimensional fluid flow in rotating bioreactors for tissue engineering. J. Biomed. Mater. Res. A 69, 205, 2004.
49. Sung HJ, Meredith C, Johnson C, Galis ZS. The effect of scaffold degradation rate on three-dimensional cell growth and angiogenesis. Biomaterials 25, 5735, 2004.
50. Gabbiani G, Gabbiani F, Heimark RL, Schwartz SM. Organization of actin cytoskeleton during early endothelial regeneration in vitro. J. Cell Sci. 66, 39, 1984.
51. Peters MC, Polverini PJ, Mooney DJ. Engineering vascular networks in porous polymer matrices. J. Biomed. Mater. Res. 60, 668, 2002.
52. Papadopoulos S, Jurgens KD, Gros G. Protein diffusion in living skeletal muscle fibers: dependence on protein size, fiber type, and contraction. Biophys. J. 79, 2084, 2000.
53. Epstein SE, Kornowski R, Fuchs S, Dvorak HF. Angiogenesis therapy: amidst the hype, the neglected potential for serious side effects. Circulation 104, 115, 2001.
54. Capitosti SM, Hansen TP, Brown ML. Facile synthesis of an azido-labeled thalidomide analogue. Org. Lett. 5, 2865, 2003.
55. Dasgupta D, Park H, Harriman GC, Georg GI, Himes RH. Synthesis of a photoaffinity taxol analogue and its use in labeling tubulin. J. Med. Chem. 37, 2976, 1994.
56. Swindell CS, Heerding JM, Krauss NE, Horwitz SB, Rao S, Ringel I. Characterization of two taxol photoaffinity analogues bearing azide and benzophenone-related photoreactive substituents in the A-ring side chain. J. Med. Chem. 37, 1446, 1994.