-
1
-
-
12444334643
-
Lipotoxicity an imbalance between lipogenesis de novo and fatty acid oxidation
-
Lelliott, C. & Vidal-Puig, A. J. Lipotoxicity, an imbalance between lipogenesis de novo and fatty acid oxidation. Int. J. Obes. Relat. Metab. Disord. 28, S22-S28 (2004).
-
(2004)
Int. J. Obes. Relat. Metab. Disord.
, vol.28
-
-
Lelliott, C.1
Vidal-Puig, A.J.2
-
2
-
-
33747356154
-
Adipose tissue: From lipid storage compartment to endocrine organ
-
Scherer, P. E. Adipose tissue: from lipid storage compartment to endocrine organ. Diabetes 55, 1537-1545 (2006).
-
(2006)
Diabetes
, vol.55
, pp. 1537-1545
-
-
Scherer, P.E.1
-
3
-
-
0036384894
-
Brown adipose tissue: A factor to consider in symmetrical tracer uptake in the neck and upper chest region
-
Hany, T. F. et al. Brown adipose tissue: a factor to consider in symmetrical tracer uptake in the neck and upper chest region. Eur. J. Nucl. Med. Mol. Imaging 29, 1393-1398 (2002).
-
(2002)
Eur. J. Nucl. Med. Mol. Imaging
, vol.29
, pp. 1393-1398
-
-
Hany, T.F.1
-
4
-
-
34547631960
-
Unexpected evidence for active brown adipose tissue in adult humans
-
Nedergaard, J. et al. Unexpected evidence for active brown adipose tissue in adult humans. Am. J. Physiol. Endocrinol. Metab. 293, E444-E452 (2007).
-
(2007)
Am. J. Physiol. Endocrinol. Metab.
, vol.293
-
-
Nedergaard, J.1
-
5
-
-
64349123664
-
Functional brown adipose tissue in healthy adults
-
Virtanen, K. A. et al. Functional brown adipose tissue in healthy adults. N. Engl. J. Med. 360, 1518-1525 (2009).
-
(2009)
N. Engl. J. Med.
, vol.360
, pp. 1518-1525
-
-
Virtanen, K.A.1
-
6
-
-
64349095231
-
Cold-activated brown adipose tissue in healthy men
-
van Marken Lichtenbelt, W. D. et al. Cold-activated brown adipose tissue in healthy men. N. Engl. J. Med. 360, 1500-1508 (2009).
-
(2009)
N. Engl. J. Med.
, vol.360
, pp. 1500-1508
-
-
Van Marken Lichtenbelt, W.D.1
-
7
-
-
64349105205
-
Identification and importance of brown adipose tissue in adult humans
-
Cypess, A. M. et al. Identification and importance of brown adipose tissue in adult humans. N. Engl. J. Med. 360, 1509-1517 (2009).
-
(2009)
N. Engl. J. Med.
, vol.360
, pp. 1509-1517
-
-
Cypess, A.M.1
-
8
-
-
67650242165
-
High incidence of metabolically active brown adipose effects of cold exposure and adiposity
-
Saito, M. et al. High incidence of metabolically active brown adipose effects of cold exposure and adiposity. Diabetes 58, 1526-1531 (2009).
-
(2009)
Diabetes
, vol.58
, pp. 1526-1531
-
-
Saito, M.1
-
9
-
-
0347989317
-
Brown adipose tissue: Function and physiological significance
-
Cannon, B. & Nedergaard, J. Brown adipose tissue: function and physiological significance. Physiol. Rev. 84, 277-359 (2004).
-
(2004)
Physiol. Rev.
, vol.84
, pp. 277-359
-
-
Cannon, B.1
Nedergaard, J.2
-
10
-
-
77949328118
-
Thermogenesis challenges the adipostat hypothesis for body-weight control
-
Cannon, B. & Nedergaard, J. Thermogenesis challenges the adipostat hypothesis for body-weight control. Proc. Nutr. Soc. 68, 401-407 (2009).
-
(2009)
Proc. Nutr. Soc.
, vol.68
, pp. 401-407
-
-
Cannon, B.1
Nedergaard, J.2
-
11
-
-
58749091645
-
UCP1 ablation induces obesity and abolishes diet-induced thermogenesis in mice exempt from thermal stress by living at thermoneutrality
-
Feldmann, H. M., Golozoubova, V., Cannon, B. & Nedergaard, J. UCP1 ablation induces obesity and abolishes diet-induced thermogenesis in mice exempt from thermal stress by living at thermoneutrality. Cell Metab. 9, 203-209 (2009).
-
(2009)
Cell Metab.
, vol.9
, pp. 203-209
-
-
Feldmann, H.M.1
Golozoubova, V.2
Cannon, B.3
Nedergaard, J.4
-
12
-
-
0027731309
-
Development of obesity in transgenic mice after genetic ablation of adipose tissue
-
Lowell, B. B. et al. Development of obesity in transgenic mice after genetic ablation of adipose tissue. Nature 366, 740-742 (1993).
-
(1993)
Nature
, vol.366
, pp. 740-742
-
-
Lowell, B.B.1
-
13
-
-
79751503329
-
Brown adipose tissue activity controls triglyceride clearance
-
Bartelt, A. et al. Brown adipose tissue activity controls triglyceride clearance. Nature Med. 17, 200-205 (2011).
-
(2011)
Nature Med.
, vol.17
, pp. 200-205
-
-
Bartelt, A.1
-
14
-
-
0028945818
-
Metabolic alterations associated with the antidiabetic effect of β 3-adrenergic receptor agonists in obese mice
-
Arbeeny, C. M., Meyers, D. S., Hillyer, D. E. & Bergquist, K. E. Metabolic alterations associated with the antidiabetic effect of β 3-adrenergic receptor agonists in obese mice. Am. J. Physiol. 268, E678-E684 (1995).
-
(1995)
Am. J. Physiol.
, vol.268
-
-
Arbeeny, C.M.1
Meyers, D.S.2
Hillyer, D.E.3
Bergquist, K.E.4
-
15
-
-
0020693920
-
Luxuskonsumption diet-induced thermogenesis and brown fat: The case in favour
-
Rothwell, N. J. & Stock, M. J. Luxuskonsumption, diet-induced thermogenesis and brown fat: the case in favour. Clin. Sci. 64, 19-23 (1983).
-
(1983)
Clin. Sci.
, vol.64
, pp. 19-23
-
-
Rothwell, N.J.1
Stock, M.J.2
-
16
-
-
0024162042
-
Epididymal white adipose tissue after cold stress in rats. I. Nonmitochondrial changes
-
Loncar, D., Afzelius, B. A. & Cannon, B. Epididymal white adipose tissue after cold stress in rats. I. Nonmitochondrial changes. J. Ultrastruct. Mol. Struct. Res. 101, 109-122 (1988).
-
(1988)
J. Ultrastruct. Mol. Struct. Res.
, vol.101
, pp. 109-122
-
-
Loncar, D.1
Afzelius, B.A.2
Cannon, B.3
-
17
-
-
0021319695
-
Brown adipose tissue in the parametrial fat pad of the mouse
-
Young, P., Arch, J. R. & Ashwell, M. Brown adipose tissue in the parametrial fat pad of the mouse. FEBS Lett. 167, 10-14 (1984).
-
(1984)
FEBS Lett.
, vol.167
, pp. 10-14
-
-
Young, P.1
Arch, J.R.2
Ashwell, M.3
-
18
-
-
84864287504
-
Beige adipocytes are a distinct type of thermogenic fat cell in mouse and human
-
Wu, J. et al. Beige adipocytes are a distinct type of thermogenic fat cell in mouse and human. Cell 150, 366-376 (2012).
-
(2012)
Cell
, vol.150
, pp. 366-376
-
-
Wu, J.1
-
19
-
-
83455198397
-
Recruited vs. Nonrecruited molecular signatures of brown, "brite," and white adipose tissues
-
Waldén, T. B. et al. Recruited vs. nonrecruited molecular signatures of brown,"brite," and white adipose tissues. Am. J. Physiol. Endocrinol. Metab. 302, E19-E31 (2012).
-
(2012)
Am. J. Physiol. Endocrinol. Metab.
, vol.302
-
-
Waldén, T.B.1
-
20
-
-
84869233588
-
Human BAT possesses molecular signatures that resemble beige/brite cells
-
Sharp, L. Z. et al. Human BAT possesses molecular signatures that resemble beige/brite cells. PLoS ONE 7, e49452 (2012).
-
(2012)
PLoS ONE
, vol.7
-
-
Sharp, L.Z.1
-
21
-
-
77950226740
-
Chronic peroxisome proliferator-activated receptor γ (PPAR-γ) activation of epididymally derived white adipocyte cultures reveals a population of thermogenically competent UCP1-containing adipocytes molecularly distinct from classic brown adipocyt
-
Petrovic, N. et al. Chronic peroxisome proliferator-activated receptor γ (PPAR-γ) activation of epididymally derived white adipocyte cultures reveals a population of thermogenically competent, UCP1-containing adipocytes molecularly distinct from classic brown adipocyt. J. Biol. Chem. 285, 7153-7164 (2010).
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 7153-7164
-
-
Petrovic, N.1
-
22
-
-
84890234667
-
UCP1 in brite/beige adipose tissue mitochondria is functionally thermogenic
-
Shabalina, I. G. et al. UCP1 in brite/beige adipose tissue mitochondria is functionally thermogenic. Cell Rep. 5, 1196-1203 (2013).
-
(2013)
Cell Rep.
, vol.5
, pp. 1196-1203
-
-
Shabalina, I.G.1
-
23
-
-
76049099665
-
Adipose tissue expandability, lipotoxicity and the metabolic syndrome-an allostatic perspective
-
Virtue, S. & Vidal-Puig, A. Adipose tissue expandability, lipotoxicity and the metabolic syndrome-an allostatic perspective. Biochim. Biophys. Acta 1801, 338-349 (2010).
-
(2010)
Biochim. Biophys. Acta
, vol.1801
, pp. 338-349
-
-
Virtue, S.1
Vidal-Puig, A.2
-
24
-
-
53549134683
-
Identification of white adipocyte progenitor cells in vivo
-
Rodeheffer, M. S., Birsoy, K. & Friedman, J. M. Identification of white adipocyte progenitor cells in vivo. Cell 135, 240-249 (2008).
-
(2008)
Cell
, vol.135
, pp. 240-249
-
-
Rodeheffer, M.S.1
Birsoy, K.2
Friedman, J.M.3
-
25
-
-
53549130485
-
White fat progenitor cells reside in the adipose vasculature
-
Tang, W. et al. White fat progenitor cells reside in the adipose vasculature. Science 322, 583-586 (2008).
-
(2008)
Science
, vol.322
, pp. 583-586
-
-
Tang, W.1
-
26
-
-
84888359805
-
Adipogenesis: New insights into brown adipose tissue differentiation
-
Carobbio, S., Rosen, B. & Vidal-Puig, A. Adipogenesis: new insights into brown adipose tissue differentiation. J. Mol. Endocrinol. 51, T75-T85 (2013).
-
(2013)
J. Mol. Endocrinol.
, vol.51
-
-
Carobbio, S.1
Rosen, B.2
Vidal-Puig, A.3
-
27
-
-
0034664770
-
Pax7 is required for the specification of myogenic satellite cells
-
Seale, P. et al. Pax7 is required for the specification of myogenic satellite cells. Cell 102, 777-786 (2000).
-
(2000)
Cell
, vol.102
, pp. 777-786
-
-
Seale, P.1
-
28
-
-
77954741222
-
Inducible lineage tracing of Pax7-descendant cells reveals embryonic origin of adult satellite cells
-
Lepper, C. & Fan, C. Inducible lineage tracing of Pax7-descendant cells reveals embryonic origin of adult satellite cells. Genesis 48, 424-436 (2010)
-
(2010)
Genesis
, vol.48
, pp. 424-436
-
-
Lepper, C.1
Fan, C.2
-
29
-
-
84873327762
-
MicroRNA-133 controls brown adipose determination in skeletal muscle satellite cells by targeting Prdm16
-
Yin, H. et al. MicroRNA-133 controls brown adipose determination in skeletal muscle satellite cells by targeting Prdm16. Cell Metab. 17, 210-224 (2013).
-
(2013)
Cell Metab.
, vol.17
, pp. 210-224
-
-
Yin, H.1
-
30
-
-
50049122271
-
PRDM16 controls a brown fat/skeletal muscle switch
-
Seale, P. et al. PRDM16 controls a brown fat/skeletal muscle switch. Nature 454, 961-967 (2008).
-
(2008)
Nature
, vol.454
, pp. 961-967
-
-
Seale, P.1
-
31
-
-
34248372084
-
Myogenic gene expression signature establishes that brown and white adipocytes originate from distinct cell lineages
-
Timmons, J. A. et al. Myogenic gene expression signature establishes that brown and white adipocytes originate from distinct cell lineages. Proc. Natl Acad. Sci. USA 104, 4401-4406 (2007).
-
(2007)
Proc. Natl Acad. Sci. USA
, vol.104
, pp. 4401-4406
-
-
Timmons, J.A.1
-
32
-
-
58149217061
-
Distinct expression of muscle-specific microRNAs (myomirs) in brown adipocytes
-
Walden, T. B., Timmons, J. A., Keller, P., Nedergaard, J. & Cannon, B. Distinct expression of muscle-specific microRNAs (myomirs) in brown adipocytes. J. Cell. Physiol. 218, 444-449 (2009).
-
(2009)
J. Cell. Physiol.
, vol.218
, pp. 444-449
-
-
Walden, T.B.1
Timmons, J.A.2
Keller, P.3
Nedergaard, J.4
Cannon, B.5
-
33
-
-
84865792944
-
PTEN loss in the Myf5 lineage redistributes body fat and reveals subsets of white adipocytes that arise from Myf5 precursors
-
Sanchez-Gurmaches, J. et al. PTEN loss in the Myf5 lineage redistributes body fat and reveals subsets of white adipocytes that arise from Myf5 precursors. Cell Metab. 16, 348-362 (2012).
-
(2012)
Cell Metab.
, vol.16
, pp. 348-362
-
-
Sanchez-Gurmaches, J.1
-
34
-
-
84881259220
-
Distinct populations of adipogenic and myogenic Myf5-lineage progenitors in white adipose tissues
-
Shan, T. et al. Distinct populations of adipogenic and myogenic Myf5-lineage progenitors in white adipose tissues. J. Lipid Res. 54, 2214-2224 (2013).
-
(2013)
J. Lipid Res.
, vol.54
, pp. 2214-2224
-
-
Shan, T.1
-
35
-
-
84856954303
-
The vascular endothelium of the adipose tissue give rise to both white and brown fat cells
-
Tran, K. V. et al. The vascular endothelium of the adipose tissue give rise to both white and brown fat cells. Cell Metab. 15, 222-229 (2012).
-
(2012)
Cell Metab.
, vol.15
, pp. 222-229
-
-
Tran, K.V.1
-
36
-
-
84856970831
-
Zfp423 expression identifies committed preadipocytes and localizes to adipose endothelial perivascular cells
-
Gupta, R. K. et al. Zfp423 expression identifies committed preadipocytes and localizes to adipose endothelial perivascular cells. Cell Metab. 15, 230-239 (2012).
-
(2012)
Cell Metab.
, vol.15
, pp. 230-239
-
-
Gupta, R.K.1
-
37
-
-
84874657953
-
Characterization of the adipocyte cellular lineage in vivo
-
Berry, R. & Rodeheffer, M. S. Characterization of the adipocyte cellular lineage in vivo. Nature Cell Biol. 15, 302-308 (2013).
-
(2013)
Nature Cell Biol.
, vol.15
, pp. 302-308
-
-
Berry, R.1
Rodeheffer, M.S.2
-
38
-
-
0031985802
-
Thiazolidinedione exposure increases the expression of uncoupling protein 1 in cultured human preadipocytes
-
Digby, J. E. et al. Thiazolidinedione exposure increases the expression of uncoupling protein 1 in cultured human preadipocytes. Diabetes 47, 138-141 (1998).
-
(1998)
Diabetes
, vol.47
, pp. 138-141
-
-
Digby, J.E.1
-
39
-
-
52649150323
-
Thermogenically competent nonadrenergic recruitment in brown preadipocytes by a PPARg agonist
-
Petrovic, N., Shabalina, I. G., Timmons, J. A., Cannon, B. & Nedergaard, J. Thermogenically competent nonadrenergic recruitment in brown preadipocytes by a PPARg agonist. Am. J. Physiol. Endocrinol. Metab. 295, E287-E296 (2008).
-
(2008)
Am. J. Physiol. Endocrinol. Metab.
, vol.295
-
-
Petrovic, N.1
Shabalina, I.G.2
Timmons, J.A.3
Cannon, B.4
Nedergaard, J.5
-
40
-
-
84878525220
-
Bi-directional interconversion of brite and white adipocytes
-
Rosenwald, M., Perdikari, A., Rülicke, T. & Wolfrum, C. Bi-directional interconversion of brite and white adipocytes. Nature Cell Biol. 15, 659-667 (2013).
-
(2013)
Nature Cell Biol.
, vol.15
, pp. 659-667
-
-
Rosenwald, M.1
Perdikari, A.2
Rülicke, T.3
Wolfrum, C.4
-
41
-
-
84887502374
-
Tracking adipogenesis during white adipose tissue development, expansion and regeneration
-
Wang, Q. A., Tao, C., Gupta, R. K. & Scherer, P. E. Tracking adipogenesis during white adipose tissue development, expansion and regeneration. Nature Med. 19, 1338-1344 (2013).
-
(2013)
Nature Med.
, vol.19
, pp. 1338-1344
-
-
Wang, Q.A.1
Tao, C.2
Gupta, R.K.3
Scherer, P.E.4
-
42
-
-
84859465056
-
In vivo identification of bipotential adipocyte progenitors recruited by β3-adrenoceptor activation and high-fat feeding
-
Lee, Y.-H., Petkova, A. P., Mottillo, E. P. & Granneman, J. G. In vivo identification of bipotential adipocyte progenitors recruited by β3-adrenoceptor activation and high-fat feeding. Cell Metab. 15, 480-491 (2012).
-
(2012)
Cell Metab.
, vol.15
, pp. 480-491
-
-
Lee, Y.-H.1
Petkova, A.P.2
Mottillo, E.P.3
Granneman, J.G.4
-
43
-
-
84883354892
-
A heterogeneous lineage origin underlies the phenotypic and molecular differences of white and beige adipocytes
-
Liu, W. et al. A heterogeneous lineage origin underlies the phenotypic and molecular differences of white and beige adipocytes. J. Cell Sci. 126, 3527-3532 (2013).
-
(2013)
J. Cell Sci.
, vol.126
, pp. 3527-3532
-
-
Liu, W.1
-
44
-
-
33748366392
-
Regulatory circuits controlling white versus brown adipocyte differentiation
-
Hansen, J. B. & Kristiansen, K. Regulatory circuits controlling white versus brown adipocyte differentiation. Biochem. J. 398, 153-168 (2006).
-
(2006)
Biochem. J.
, vol.398
, pp. 153-168
-
-
Hansen, J.B.1
Kristiansen, K.2
-
45
-
-
14844328611
-
Tissue-specific regulation of metabolic pathways through the transcriptional coactivator PGC1-α
-
Puigserver, P. Tissue-specific regulation of metabolic pathways through the transcriptional coactivator PGC1-α. Int. J. Obes. 29, S5-S9 (2005).
-
(2005)
Int. J. Obes.
, vol.29
-
-
Puigserver, P.1
-
46
-
-
34347326271
-
Transcriptional control of brown fat determination by PRDM16
-
Seale, P. et al. Transcriptional control of brown fat determination by PRDM16. Cell Metab. 6, 38-54 (2007).
-
(2007)
Cell Metab.
, vol.6
, pp. 38-54
-
-
Seale, P.1
-
47
-
-
78650945931
-
Prdm16 determines the thermogenic program of subcutaneous white adipose tissue in mice
-
Seale, P. et al. Prdm16 determines the thermogenic program of subcutaneous white adipose tissue in mice. J. Clin. Invest. 121, 96-105 (2011).
-
(2011)
J. Clin. Invest.
, vol.121
, pp. 96-105
-
-
Seale, P.1
-
48
-
-
84892702771
-
Ablation of PRDM16 and beige adipose causes metabolic dysfunction and a subcutaneous to visceral fat switch
-
Cohen, P. et al. Ablation of PRDM16 and beige adipose causes metabolic dysfunction and a subcutaneous to visceral fat switch. Cell 156, 304-316 (2014).
-
(2014)
Cell
, vol.156
, pp. 304-316
-
-
Cohen, P.1
-
49
-
-
84889604511
-
EHMT1 controls brown adipose cell fate and thermogenesis through the PRDM16 complex
-
Ohno, H., Shinoda, K., Ohyama, K., Sharp, L. Z. & Kajimura, S. EHMT1 controls brown adipose cell fate and thermogenesis through the PRDM16 complex. Nature 504, 163-167 (2013).
-
(2013)
Nature
, vol.504
, pp. 163-167
-
-
Ohno, H.1
Shinoda, K.2
Ohyama, K.3
Sharp, L.Z.4
Kajimura, S.5
-
50
-
-
20144365700
-
Nuclear trapping of the forkhead transcription factor FoxO1 via Sirt-dependent deacetylation promotes expression of glucogenetic genes
-
Frescas, D., Valenti, L. & Accili, D. Nuclear trapping of the forkhead transcription factor FoxO1 via Sirt-dependent deacetylation promotes expression of glucogenetic genes. J. Biol. Chem. 280, 20589-20595 (2005).
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 20589-20595
-
-
Frescas, D.1
Valenti, L.2
Accili, D.3
-
51
-
-
14544282413
-
Nutrient control of glucose homeostasis through a complex of PGC-1α and SIRT1
-
Rodgers, J. T. et al. Nutrient control of glucose homeostasis through a complex of PGC-1α and SIRT1. Nature 434, 113-118 (2005).
-
(2005)
Nature
, vol.434
, pp. 113-118
-
-
Rodgers, J.T.1
-
52
-
-
33845399894
-
Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1α
-
Lagouge, M. et al. Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1α. Cell 127, 1109-1122 (2006).
-
(2006)
Cell
, vol.127
, pp. 1109-1122
-
-
Lagouge, M.1
-
53
-
-
0043244921
-
Sir2 regulates skeletal muscle differentiation as a potential sensor of the redox state
-
Fulco, M. et al. Sir2 regulates skeletal muscle differentiation as a potential sensor of the redox state. Mol. Cell 12, 51-62 (2003).
-
(2003)
Mol. Cell
, vol.12
, pp. 51-62
-
-
Fulco, M.1
-
54
-
-
84864615516
-
Brown remodeling of white adipose tissue by SirT1-dependent deacetylation of Pparγ
-
Qiang, L. et al. Brown remodeling of white adipose tissue by SirT1-dependent deacetylation of Pparγ. Cell 150, 620-632 (2012).
-
(2012)
Cell
, vol.150
, pp. 620-632
-
-
Qiang, L.1
-
55
-
-
84883149316
-
MicroRNA networks regulate development of brown adipocytes
-
Trajkovski, M. & Lodish, H. MicroRNA networks regulate development of brown adipocytes. Trends Endocrinol. Metab. 24, 442-450 (2013).
-
(2013)
Trends Endocrinol. Metab.
, vol.24
, pp. 442-450
-
-
Trajkovski, M.1
Lodish, H.2
-
56
-
-
84877747920
-
MiR-155 regulates differentiation of brown and beige adipocytes via a bistable circuit
-
Chen, Y. et al. miR-155 regulates differentiation of brown and beige adipocytes via a bistable circuit. Nature Commun. 4, 1769 (2013).
-
(2013)
Nature Commun.
, vol.4
, pp. 1769
-
-
Chen, Y.1
-
57
-
-
84892678138
-
MiR-27 orchestrates the transcriptional regulation of brown adipogenesis
-
Sun, L. & Trajkovski, M. MiR-27 orchestrates the transcriptional regulation of brown adipogenesis. Metabolism 63, 272-282 (2014).
-
(2014)
Metabolism
, vol.63
, pp. 272-282
-
-
Sun, L.1
Trajkovski, M.2
-
58
-
-
84860009214
-
Essential role for miR-196a in brown adipogenesis of white fat progenitor cells
-
Mori, M., Nakagami, H., Rodriguez-Araujo, G., Nimura, K. & Kaneda, Y. Essential role for miR-196a in brown adipogenesis of white fat progenitor cells. PLoS Biol. 10, e1001314 (2012).
-
(2012)
PLoS Biol.
, vol.10
-
-
Mori, M.1
Nakagami, H.2
Rodriguez-Araujo, G.3
Nimura, K.4
Kaneda, Y.5
-
59
-
-
79960984113
-
MiR-193b-365, a brown fat enriched microRNA cluster, is essential for brown fat differentiation
-
Sun, L. et al. MiR-193b-365, a brown fat enriched microRNA cluster, is essential for brown fat differentiation. Nature Cell Biol. 13, 958-965 (2011).
-
(2011)
Nature Cell Biol.
, vol.13
, pp. 958-965
-
-
Sun, L.1
-
60
-
-
84870595878
-
MyomiR-133 regulates brown fat differentiation through Prdm16
-
Trajkovski, M., Ahmed, K., Esau, C. C. & Stoffel, M. MyomiR-133 regulates brown fat differentiation through Prdm16. Nature Cell Biol. 14, 1330-1335 (2012).
-
(2012)
Nature Cell Biol.
, vol.14
, pp. 1330-1335
-
-
Trajkovski, M.1
Ahmed, K.2
Esau, C.C.3
Stoffel, M.4
-
61
-
-
84880812042
-
MiR-133a regulates adipocyte browning in vivo
-
Liu, W. et al. miR-133a regulates adipocyte browning in vivo. PLoS Genet. 9, e1003626 (2013).
-
(2013)
PLoS Genet.
, vol.9
-
-
Liu, W.1
-
62
-
-
33846049659
-
Insulin and insulin resistance
-
Wilcox, G. Insulin and insulin resistance. Clin. Biochem. Rev. 26, 19-39 (2005).
-
(2005)
Clin. Biochem. Rev.
, vol.26
, pp. 19-39
-
-
Wilcox, G.1
-
63
-
-
84893428884
-
Sympathetic nervous system control of triglyceride metabolism: Novel concepts derived from recent studies
-
Geerling, J. J. et al. Sympathetic nervous system control of triglyceride metabolism: novel concepts derived from recent studies. J. Lipid Res. 55, 180-189 (2014).
-
(2014)
J. Lipid Res.
, vol.55
, pp. 180-189
-
-
Geerling, J.J.1
-
64
-
-
0035787319
-
The β-adrenergic receptors and the control of adipose tissue metabolism and thermogenesis
-
Collins, S. & Surwit, R. S. The β-adrenergic receptors and the control of adipose tissue metabolism and thermogenesis. Recent Prog. Horm. Res. 56, 309-328 (2001).
-
(2001)
Recent Prog. Horm. Res.
, vol.56
, pp. 309-328
-
-
Collins, S.1
Surwit, R.S.2
-
65
-
-
84879590350
-
Brown adipose tissue: Development, metabolism and beyond
-
Schulz, T. J. & Tseng, Y.-H. Brown adipose tissue: development, metabolism and beyond. Biochem. J. 453, 167-178 (2013).
-
(2013)
Biochem. J.
, vol.453
, pp. 167-178
-
-
Schulz, T.J.1
Tseng, Y.-H.2
-
66
-
-
84875367849
-
Brown-fat paucity due to impaired BMP signalling induces compensatory browning of white fat
-
Schulz, T. J. et al. Brown-fat paucity due to impaired BMP signalling induces compensatory browning of white fat. Nature 495, 379-383 (2013).
-
(2013)
Nature
, vol.495
, pp. 379-383
-
-
Schulz, T.J.1
-
67
-
-
36849095595
-
Cardiovascular responses to weight management and sibutramine in high-risk subjects: An analysis from the SCOUT trial
-
Torp-Pedersen, C. et al. Cardiovascular responses to weight management and sibutramine in high-risk subjects: an analysis from the SCOUT trial. Eur. Heart J. 28, 2915-2923 (2007).
-
(2007)
Eur. Heart J.
, vol.28
, pp. 2915-2923
-
-
Torp-Pedersen, C.1
-
68
-
-
0037066575
-
β3-adrenoceptor agonists: Potential, pitfalls and progress
-
Arch, J. R. S. β3-adrenoceptor agonists: potential, pitfalls and progress. Eur. J. Pharmacol. 440, 99-107 (2002).
-
(2002)
Eur. J. Pharmacol.
, vol.440
, pp. 99-107
-
-
Arch, J.R.S.1
-
69
-
-
17944377509
-
FOXC2 is a winged helix gene that counteracts obesity, hypertriglyceridemia, and diet-induced insulin resistance
-
Cederberg, A. et al. FOXC2 is a winged helix gene that counteracts obesity, hypertriglyceridemia, and diet-induced insulin resistance. Cell 106, 563-573 (2001).
-
(2001)
Cell
, vol.106
, pp. 563-573
-
-
Cederberg, A.1
-
70
-
-
33745965635
-
Reduced PDE4 expression and activity contributes to enhanced catecholamine-induced cAMP accumulation in adipocytes from FOXC2 transgenic mice
-
Grønning, L. M. et al. Reduced PDE4 expression and activity contributes to enhanced catecholamine-induced cAMP accumulation in adipocytes from FOXC2 transgenic mice. FEBS Lett. 580, 4126-4130 (2006).
-
(2006)
FEBS Lett.
, vol.580
, pp. 4126-4130
-
-
Grønning, L.M.1
-
71
-
-
79551610057
-
The adipocyte-expressed forkhead transcription factor Foxc2 regulates metabolism through altered mitochondrial function
-
Lidell, M. E. et al. The adipocyte-expressed forkhead transcription factor Foxc2 regulates metabolism through altered mitochondrial function. Diabetes 60, 427-435 (2011).
-
(2011)
Diabetes
, vol.60
, pp. 427-435
-
-
Lidell, M.E.1
-
72
-
-
84860850964
-
BMP8B increases brown adipose tissue thermogenesis through both central and peripheral actions
-
Whittle, A. J. et al. BMP8B increases brown adipose tissue thermogenesis through both central and peripheral actions. Cell 149, 871-885 (2012).
-
(2012)
Cell
, vol.149
, pp. 871-885
-
-
Whittle, A.J.1
-
73
-
-
50049127055
-
New role of bone morphogenetic protein 7 in brown adipogenesis and energy expenditure
-
Tseng, Y.-H. et al. New role of bone morphogenetic protein 7 in brown adipogenesis and energy expenditure. Nature 454, 1000-1004 (2008).
-
(2008)
Nature
, vol.454
, pp. 1000-1004
-
-
Tseng, Y.-H.1
-
74
-
-
84884183691
-
BMP7 activates brown adipose tissue and reduces diet-induced obesity only at subthermoneutrality
-
Boon, M. R. et al. BMP7 activates brown adipose tissue and reduces diet-induced obesity only at subthermoneutrality. PLoS ONE 8, e74083 (2013).
-
(2013)
PLoS ONE
, vol.8
-
-
Boon, M.R.1
-
75
-
-
84877585823
-
Beyond the sympathetic tone: The new brown fat activators
-
Villarroya, F. & Vidal-Puig, A. Beyond the sympathetic tone: the new brown fat activators. Cell Metab. 17, 638-643 (2013).
-
(2013)
Cell Metab.
, vol.17
, pp. 638-643
-
-
Villarroya, F.1
Vidal-Puig, A.2
-
76
-
-
79953886306
-
Thermogenic activation induces FGF21 expression and release in brown adipose tissue
-
Hondares, E. et al. Thermogenic activation induces FGF21 expression and release in brown adipose tissue. J. Biol. Chem. 286, 12983-12990 (2011).
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 12983-12990
-
-
Hondares, E.1
-
77
-
-
84863012022
-
FGF21 regulates PGC-1α and browning of white adipose tissues in adaptive thermogenesis
-
Fisher, F. M. et al. FGF21 regulates PGC-1α and browning of white adipose tissues in adaptive thermogenesis. Genes Dev. 26, 271-281 (2012).
-
(2012)
Genes Dev.
, vol.26
, pp. 271-281
-
-
Fisher, F.M.1
-
78
-
-
42949109612
-
Control of lipolysis by natriuretic peptides and cyclic GMP
-
Lafontan, M. et al. Control of lipolysis by natriuretic peptides and cyclic GMP. Trends Endocrinol. Metab. 19, 130-137 (2008).
-
(2008)
Trends Endocrinol. Metab.
, vol.19
, pp. 130-137
-
-
Lafontan, M.1
-
79
-
-
84863229962
-
Cardiac natriuretic peptides act via p38 MAPK to induce the brown fat thermogenic program in mouse and human adipocytes
-
Bordicchia, M. et al. Cardiac natriuretic peptides act via p38 MAPK to induce the brown fat thermogenic program in mouse and human adipocytes. J. Clin. Invest. 122, 1022-1036 (2012).
-
(2012)
J. Clin. Invest.
, vol.122
, pp. 1022-1036
-
-
Bordicchia, M.1
-
80
-
-
79960955885
-
Cardiotrophin-1 is a key regulator of glucose and lipid metabolism
-
Moreno-Aliaga, M. J. et al. Cardiotrophin-1 is a key regulator of glucose and lipid metabolism. Cell Metab. 14, 242-253 (2011).
-
(2011)
Cell Metab.
, vol.14
, pp. 242-253
-
-
Moreno-Aliaga, M.J.1
-
81
-
-
84862776702
-
A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis
-
Boström, P. et al. A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis. Nature 481, 463-468 (2012).
-
(2012)
Nature
, vol.481
, pp. 463-468
-
-
Boström, P.1
-
82
-
-
80052358980
-
Therapeutic strategies for the clinical blockade of IL-6/gp130 signaling
-
Jones, S. A., Scheller, J. & Rose-John, S. Therapeutic strategies for the clinical blockade of IL-6/gp130 signaling. J. Clin. Invest. 121, 3375-3383 (2011).
-
(2011)
J. Clin. Invest.
, vol.121
, pp. 3375-3383
-
-
Jones, S.A.1
Scheller, J.2
Rose-John, S.3
-
83
-
-
84876133911
-
FNDC5/irisin is not only a myokine but also an adipokine
-
Roca-Rivada, A. et al. FNDC5/irisin is not only a myokine but also an adipokine. PLoS ONE 8, e60563 (2013).
-
(2013)
PLoS ONE
, vol.8
-
-
Roca-Rivada, A.1
-
84
-
-
84893064752
-
Irisin stimulates browning of white adipocytes through mitogen-activated protein kinase p38 MAP kinase and ERK MAP kinase signaling
-
Zhang, Y. et al. Irisin stimulates browning of white adipocytes through mitogen-activated protein kinase p38 MAP kinase and ERK MAP kinase signaling. Diabetes 63, 514-525 (2014).
-
(2014)
Diabetes
, vol.63
, pp. 514-525
-
-
Zhang, Y.1
-
85
-
-
84898648553
-
Hormone-induced mitochondrial fission is utilized by brown adipocytes as an amplification pathway for energy expenditure
-
Wikstrom, J. D. et al. Hormone-induced mitochondrial fission is utilized by brown adipocytes as an amplification pathway for energy expenditure. EMBO J. 33, 418-436 (2014).
-
(2014)
EMBO J.
, vol.33
, pp. 418-436
-
-
Wikstrom, J.D.1
-
86
-
-
82555186955
-
Alternatively activated macrophages produce catecholamines to sustain adaptive thermogenesis
-
Nguyen, K. D. et al. Alternatively activated macrophages produce catecholamines to sustain adaptive thermogenesis. Nature 480, 104-108 (2011).
-
(2011)
Nature
, vol.480
, pp. 104-108
-
-
Nguyen, K.D.1
-
87
-
-
57849153917
-
Hypoxia-independent angiogenesis in adipose tissues during cold acclimation
-
Xue, Y. et al. Hypoxia-independent angiogenesis in adipose tissues during cold acclimation. Cell Metab. 9, 99-109 (2009).
-
(2009)
Cell Metab.
, vol.9
, pp. 99-109
-
-
Xue, Y.1
-
88
-
-
84859410604
-
The adipose organ of obesity-prone C57BL/6J mice is composed of mixed white and brown adipocytes
-
Vitali, A. et al. The adipose organ of obesity-prone C57BL/6J mice is composed of mixed white and brown adipocytes. J. Lipid Res. 53, 619-629 (2012).
-
(2012)
J. Lipid Res.
, vol.53
, pp. 619-629
-
-
Vitali, A.1
-
89
-
-
48249143579
-
FOXC2 controls Ang-2 expression and modulates angiogenesis, vascular patterning, remodeling, and functions in adipose tissue
-
Xue, Y. et al. FOXC2 controls Ang-2 expression and modulates angiogenesis, vascular patterning, remodeling, and functions in adipose tissue. Proc. Natl Acad. Sci. USA 105, 10167-10172 (2008).
-
(2008)
Proc. Natl Acad. Sci. USA
, vol.105
, pp. 10167-10172
-
-
Xue, Y.1
-
90
-
-
84863198909
-
Adipose tissue overexpression of vascular endothelial growth factor protects against diet-induced obesity and insulin resistance
-
Elias, I. et al. Adipose tissue overexpression of vascular endothelial growth factor protects against diet-induced obesity and insulin resistance. Diabetes 61, 1801-1813 (2012).
-
(2012)
Diabetes
, vol.61
, pp. 1801-1813
-
-
Elias, I.1
-
91
-
-
84859615812
-
Dichotomous effects of VEGF-A on adipose tissue dysfunction
-
Sun, K. et al. Dichotomous effects of VEGF-A on adipose tissue dysfunction. Proc. Natl Acad. Sci. USA 109, 5874-5879 (2012).
-
(2012)
Proc. Natl Acad. Sci. USA
, vol.109
, pp. 5874-5879
-
-
Sun, K.1
-
92
-
-
54349124582
-
Hypoxia and the endocrine and signalling role of white adipose tissue
-
Trayhurn, P., Wang, B. & Wood, I. S. Hypoxia and the endocrine and signalling role of white adipose tissue. Arch. Physiol. Biochem. 114, 267-276 (2008).
-
(2008)
Arch. Physiol. Biochem.
, vol.114
, pp. 267-276
-
-
Trayhurn, P.1
Wang, B.2
Wood, I.S.3
-
93
-
-
79151484704
-
Adipokines in inflammation and metabolic disease
-
Ouchi, N., Parker, J. L., Lugus, J. J. & Walsh, K. Adipokines in inflammation and metabolic disease. Nature Rev. Immunol. 11, 85-97 (2011).
-
(2011)
Nature Rev. Immunol.
, vol.11
, pp. 85-97
-
-
Ouchi, N.1
Parker, J.L.2
Lugus, J.J.3
Walsh, K.4
-
94
-
-
2942703809
-
Reversal of obesity by targeted ablation of adipose tissue
-
Kolonin, M. G., Saha, P. K., Chan, L., Pasqualini, R. & Arap, W. Reversal of obesity by targeted ablation of adipose tissue. Nature Med. 10, 625-632 (2004).
-
(2004)
Nature Med.
, vol.10
, pp. 625-632
-
-
Kolonin, M.G.1
Saha, P.K.2
Chan, L.3
Pasqualini, R.4
Arap, W.5
-
95
-
-
0036678477
-
Adipose tissue mass can be regulated through the vasculature
-
Rupnick, M. A. et al. Adipose tissue mass can be regulated through the vasculature. Proc. Natl Acad. Sci. USA 99, 10730-10735 (2002).
-
(2002)
Proc. Natl Acad. Sci. USA
, vol.99
, pp. 10730-10735
-
-
Rupnick, M.A.1
-
96
-
-
0032520921
-
Troglitazone increases the number of small adipocytes without the change of white adipose tissue mass in obese Zucker rats
-
Okuno, A. et al. Troglitazone increases the number of small adipocytes without the change of white adipose tissue mass in obese Zucker rats. J. Clin. Invest. 101, 1354-1361 (1998).
-
(1998)
J. Clin. Invest.
, vol.101
, pp. 1354-1361
-
-
Okuno, A.1
-
97
-
-
0035430576
-
Effects of pioplitazone on adipose tissue remodeling within the setting of obesity and insulin resistance
-
De Souza, C. J. et al. Effects of pioplitazone on adipose tissue remodeling within the setting of obesity and insulin resistance. Diabetes 50, 1863-1871 (2001).
-
(2001)
Diabetes
, vol.50
, pp. 1863-1871
-
-
De Souza, C.J.1
-
98
-
-
34848872799
-
Obesity-associated improvements in metabolic profile through expansion of adipose tissue
-
Kim, J. Y. et al. Obesity-associated improvements in metabolic profile through expansion of adipose tissue. J. Clin. Invest. 117, 2621-2637 (2007).
-
(2007)
J. Clin. Invest.
, vol.117
, pp. 2621-2637
-
-
Kim, J.Y.1
-
99
-
-
17944365228
-
The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity
-
Yamauchi, T. et al. The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity. Nature Med. 7, 941-946 (2001).
-
(2001)
Nature Med.
, vol.7
, pp. 941-946
-
-
Yamauchi, T.1
-
100
-
-
0035430576
-
Effects of pioglitazone on adipose tissue remodeling within the setting of obesity and insulin resistence
-
De Souza, C. J. et al. Effects of pioglitazone on adipose tissue remodeling within the setting of obesity and insulin resistence. Diabetes 50, 1863-1871 (2001).
-
(2001)
Diabetes
, vol.50
, pp. 1863-1871
-
-
De Souza, C.J.1
-
101
-
-
84870302181
-
MitoNEET-driven alterations in adipocyte mitochondrial activity reveal a crucial adaptive process that preserves insulin sensitivity in obesity
-
Kusminski, C. M. et al. MitoNEET-driven alterations in adipocyte mitochondrial activity reveal a crucial adaptive process that preserves insulin sensitivity in obesity. Nature Methods 18, 1539-1549 (2012).
-
(2012)
Nature Methods
, vol.18
, pp. 1539-1549
-
-
Kusminski, C.M.1
-
102
-
-
62849107819
-
Metabolic dysregulation and adipose tissue fibrosis: Role of collagen VI
-
Khan, T. et al. Metabolic dysregulation and adipose tissue fibrosis: role of collagen VI. Mol. Cell. Biol. 29, 1575-1591 (2009).
-
(2009)
Mol. Cell. Biol.
, vol.29
, pp. 1575-1591
-
-
Khan, T.1
-
103
-
-
84877263632
-
A classical brown adipose tissue mRNA signature partly overlaps with brite in the supraclavicular region of adult humans
-
Jespersen, N. Z. et al. A classical brown adipose tissue mRNA signature partly overlaps with brite in the supraclavicular region of adult humans. Cell Metab. 17, 798-805 (2013).
-
(2013)
Cell Metab.
, vol.17
, pp. 798-805
-
-
Jespersen, N.Z.1
-
104
-
-
84877340732
-
Evidence for two types of brown adipose tissue in humans
-
Lidell, M. E. et al. Evidence for two types of brown adipose tissue in humans. Nature Med. 19, 631-634 (2013).
-
(2013)
Nature Med.
, vol.19
, pp. 631-634
-
-
Lidell, M.E.1
-
105
-
-
84877331455
-
Anatomical localization, gene expression profiling and functional characterization of adult human neck brown fat
-
Cypess, A. M. et al. Anatomical localization, gene expression profiling and functional characterization of adult human neck brown fat. Nature Med. 19, 635-639 (2013).
-
(2013)
Nature Med.
, vol.19
, pp. 635-639
-
-
Cypess, A.M.1
-
106
-
-
0031053535
-
Immunohistochemical localization of leptin and uncoupling protein in white and brown adipose tissue
-
Cinti, S. et al. Immunohistochemical localization of leptin and uncoupling protein in white and brown adipose tissue. Endocrinology 138, 797-804 (1997).
-
(1997)
Endocrinology
, vol.138
, pp. 797-804
-
-
Cinti, S.1
-
107
-
-
84856529575
-
Brown adipose tissue oxidative metabolism contributes to energy expenditure during acute cold exposure in humans
-
Ouellet, V. et al. Brown adipose tissue oxidative metabolism contributes to energy expenditure during acute cold exposure in humans. J. Clin. Invest. 122, 545-552 (2012).
-
(2012)
J. Clin. Invest.
, vol.122
, pp. 545-552
-
-
Ouellet, V.1
-
108
-
-
79961233289
-
High prevalence of brown adipose tissue in adult humans
-
Lee, P. et al. High prevalence of brown adipose tissue in adult humans. J. Clin. Endocrinol. Metab. 96, 2450-2455 (2011).
-
(2011)
J. Clin. Endocrinol. Metab.
, vol.96
, pp. 2450-2455
-
-
Lee, P.1
-
109
-
-
84875794383
-
15O PET measurement of blood flow and oxygen consumption in cold-activated human brown fat
-
Muzik, O. et al. 15O PET measurement of blood flow and oxygen consumption in cold-activated human brown fat. J. Nucl. Med. 54, 523-531 (2013).
-
(2013)
J. Nucl. Med.
, vol.54
, pp. 523-531
-
-
Muzik, O.1
-
110
-
-
78650676545
-
Brown adipose tissue, whole-body energy expenditure, and thermogenesis in healthy adult men
-
Yoneshiro, T. et al. Brown adipose tissue, whole-body energy expenditure, and thermogenesis in healthy adult men. Obesity (Silver Spring) 19, 13-16 (2011).
-
(2011)
Obesity (Silver Spring)
, vol.19
, pp. 13-16
-
-
Yoneshiro, T.1
-
111
-
-
77954303930
-
Impact of age on the relationships of brown adipose tissue with sex and adiposity in humans
-
Pfannenberg, C. et al. Impact of age on the relationships of brown adipose tissue with sex and adiposity in humans. Diabetes 59, 1789-1793 (2010).
-
(2010)
Diabetes
, vol.59
, pp. 1789-1793
-
-
Pfannenberg, C.1
-
112
-
-
78650098848
-
Outdoor temperture, age, sex, body mass index, and diabetic status determine the prevalence, mass, and glucose-uptake of 18F-FDG-detected BAT in humans
-
Ouellet, V. et al. Outdoor temperture, age, sex, body mass index, and diabetic status determine the prevalence, mass, and glucose-uptake of 18F-FDG-detected BAT in humans. J. Clin. Endocrinol. Metab. 96, 192-199 (2011).
-
(2011)
J. Clin. Endocrinol. Metab.
, vol.96
, pp. 192-199
-
-
Ouellet, V.1
-
113
-
-
80052139636
-
Age-related decrease in cold-activated brown adipose tissue and accumulation of body fat in healthy humans
-
Yoneshiro, T. et al. Age-related decrease in cold-activated brown adipose tissue and accumulation of body fat in healthy humans. Obesity (Silver Spring) 19, 1755-1760 (2011).
-
(2011)
Obesity (Silver Spring)
, vol.19
, pp. 1755-1760
-
-
Yoneshiro, T.1
-
114
-
-
84867877438
-
Thermal imaging to assess age-related changes of skin temperature within the supraclavicular region co-locating with brown adipose tissue in healthy children
-
Symonds, M. E. et al. Thermal imaging to assess age-related changes of skin temperature within the supraclavicular region co-locating with brown adipose tissue in healthy children. J. Pediatr. 161, 892-898 (2012).
-
(2012)
J. Pediatr.
, vol.161
, pp. 892-898
-
-
Symonds, M.E.1
-
115
-
-
84881260642
-
Cold acclimation recruits human brown fat and increases nonshivering thermogenesis
-
van der Lans, A. A. J. J. et al. Cold acclimation recruits human brown fat and increases nonshivering thermogenesis. J. Clin. Invest. 123, 3395-3403 (2013).
-
(2013)
J. Clin. Invest.
, vol.123
, pp. 3395-3403
-
-
Van Der Lans, A.A.J.J.1
-
116
-
-
84881221754
-
Recruited brown adipose tissue as an antiobesity agent in humans
-
Yoneshiro, T. et al. Recruited brown adipose tissue as an antiobesity agent in humans. J. Clin. Invest. 123, 3404-3408 (2013).
-
(2013)
J. Clin. Invest.
, vol.123
, pp. 3404-3408
-
-
Yoneshiro, T.1
-
117
-
-
84879896962
-
Increased oxygen consumption in human adipose tissue from the brown adipose tissue region
-
Vijgen, G. H. E. J. et al. Increased oxygen consumption in human adipose tissue from the "brown adipose tissue" region. J. Clin. Endocrinol. Metab. 98, E1230-E1234 (2013).
-
(2013)
J. Clin. Endocrinol. Metab.
, vol.98
-
-
Vijgen, G.H.E.J.1
-
118
-
-
84896710569
-
Functional thermogenic beige adipogenesis is inducible in human neck fat
-
Lee, P., Werner, C. D., Kebebew, E. & Celi, F. S. Functional thermogenic beige adipogenesis is inducible in human neck fat. Int. J. Obes. 38, 170-176 (2014).
-
(2014)
Int. J. Obes.
, vol.38
, pp. 170-176
-
-
Lee, P.1
Werner, C.D.2
Kebebew, E.3
Celi, F.S.4
-
119
-
-
0033936322
-
Natriuretic peptides: A new lipolytic pathway in human adipocytes
-
Sengenès, C., Berlan, M., De Glisezinski, I., Lafontan, M. & Galitzky, J. Natriuretic peptides: a new lipolytic pathway in human adipocytes. FASEB J. 14, 1345-1351 (2000).
-
(2000)
FASEB J.
, vol.14
, pp. 1345-1351
-
-
Sengenès, C.1
Berlan, M.2
De Glisezinski, I.3
Lafontan, M.4
Galitzky, J.5
-
120
-
-
84893452569
-
Irisin and FGF21 are cold-induced endocrine activators of brown fat function in humans
-
Lee, P. et al. Irisin and FGF21 are cold-induced endocrine activators of brown fat function in humans. Cell Metab. 19, 302-309 (2014).
-
(2014)
Cell Metab.
, vol.19
, pp. 302-309
-
-
Lee, P.1
-
121
-
-
84872070199
-
Mild cold exposure modulates fibroblast growth factor 21 (FGF21) diurnal rhythm in humans: Relationship between FGF21 levels, lipolysis, and cold-induced thermogenesis
-
Lee, P. et al. Mild cold exposure modulates fibroblast growth factor 21 (FGF21) diurnal rhythm in humans: relationship between FGF21 levels, lipolysis, and cold-induced thermogenesis. J. Clin. Endocrinol. Metab. 98, E98-E102 (2013).
-
(2013)
J. Clin. Endocrinol. Metab.
, vol.98
-
-
Lee, P.1
-
122
-
-
84862777293
-
Programming human pluripotent stem cells into white and brown adipocytes
-
Ahfeldt, T. et al. Programming human pluripotent stem cells into white and brown adipocytes. Nature Cell Biol. 14, 209-219 (2012).
-
(2012)
Nature Cell Biol.
, vol.14
, pp. 209-219
-
-
Ahfeldt, T.1
-
123
-
-
84865747655
-
Production of functional classical brown adipocytes from human pluripotent stem cells using specific hemopoietin cocktail without gene transfer
-
Nishio, M. et al. Production of functional classical brown adipocytes from human pluripotent stem cells using specific hemopoietin cocktail without gene transfer. Cell Metab. 16, 394-406 (2012).
-
(2012)
Cell Metab.
, vol.16
, pp. 394-406
-
-
Nishio, M.1
-
124
-
-
84857408775
-
Reversal of type 1 diabetes in mice by brown adipose tissue transplant
-
Gunawardana, S. C. & Piston, D. W. Reversal of type 1 diabetes in mice by brown adipose tissue transplant. Diabetes 61, 674-682 (2012).
-
(2012)
Diabetes
, vol.61
, pp. 674-682
-
-
Gunawardana, S.C.1
Piston, D.W.2
-
125
-
-
84873854027
-
Brown adipose tissue regulates glucose homeostasis and insulin sensitivity
-
Stanford, K. I. et al. Brown adipose tissue regulates glucose homeostasis and insulin sensitivity. J. Clin. Invest. 123, 215-223 (2013).
-
(2013)
J. Clin. Invest.
, vol.123
, pp. 215-223
-
-
Stanford, K.I.1
|