-
1
-
-
77950408832
-
FTO effect on energy demand versus food intake
-
discussion E2
-
Speakman J.R. FTO effect on energy demand versus food intake. Nature 2010;464:E1; discussion E2
-
(2010)
Nature
, vol.464
-
-
Speakman, J.R.1
-
2
-
-
35348874911
-
Developmental origin of fat: Tracking obesity to its source
-
Gesta S, Tseng YH, Kahn CR. Developmental origin of fat: tracking obesity to its source. Cell 2007;131:242-256
-
(2007)
Cell
, vol.131
, pp. 242-256
-
-
Gesta, S.1
Tseng, Y.H.2
Kahn, C.R.3
-
4
-
-
67849089176
-
BAT: A new target for human obesity?
-
Frühbeck G, Becerril S, Sáinz N, Garrastachu P, García-Velloso MJ. BAT: a new target for human obesity? Trends Pharmacol Sci 2009;30:387-396
-
(2009)
Trends Pharmacol Sci
, vol.30
, pp. 387-396
-
-
Frühbeck, G.1
Becerril, S.2
Sáinz, N.3
Garrastachu, P.4
García-Velloso, M.J.5
-
5
-
-
0347989317
-
Brown adipose tissue: Function and physiological significance
-
Cannon B, Nedergaard J. Brown adipose tissue: function and physiological significance. Physiol Rev 2004;84:277-359
-
(2004)
Physiol Rev
, vol.84
, pp. 277-359
-
-
Cannon, B.1
Nedergaard, J.2
-
6
-
-
0036862318
-
Adipocyte differentiation and transdifferentiation: Plasticity of the adipose organ
-
Cinti S. Adipocyte differentiation and transdifferentiation: plasticity of the adipose organ. J Endocrinol Invest 2002;25:823-835
-
(2002)
J Endocrinol Invest
, vol.25
, pp. 823-835
-
-
Cinti, S.1
-
7
-
-
17944377509
-
FOXC2 is a winged helix gene that counteracts obesity, hypertriglyceridemia, and diet-induced insulin resistance
-
Cederberg A, Grønning LM, Ahrén B, Taskén K, Carlsson P, Enerbäck S. FOXC2 is a winged helix gene that counteracts obesity, hypertriglyceridemia, and diet-induced insulin resistance. Cell 2001;106:563-573
-
(2001)
Cell
, vol.106
, pp. 563-573
-
-
Cederberg, A.1
Grønning, L.M.2
Ahrén, B.3
Taskén, K.4
Carlsson, P.5
Enerbäck, S.6
-
8
-
-
58749091645
-
UCP1 ablation induces obesity and abolishes diet-induced thermogenesis in mice exempt from thermal stress by living at thermoneutrality
-
Feldmann HM, Golozoubova V, Cannon B, Nedergaard J. UCP1 ablation induces obesity and abolishes diet-induced thermogenesis in mice exempt from thermal stress by living at thermoneutrality. Cell Metab 2009;9:203-209
-
(2009)
Cell Metab
, vol.9
, pp. 203-209
-
-
Feldmann, H.M.1
Golozoubova, V.2
Cannon, B.3
Nedergaard, J.4
-
9
-
-
0035847001
-
Peroxisome proliferator-activated receptor alpha activates transcription of the brown fat uncoupling protein-1 gene. A link between regulation of the thermogenic and lipid oxidation pathways in the brown fat cell
-
Barbera MJ, Schluter A, Pedraza N, Iglesias R, Villarroya F, Giralt M. Peroxisome proliferator-activated receptor alpha activates transcription of the brown fat uncoupling protein-1 gene. A link between regulation of the thermogenic and lipid oxidation pathways in the brown fat cell. J Biol Chem 2001;276:1486-1493
-
(2001)
J Biol Chem
, vol.276
, pp. 1486-1493
-
-
Barbera, M.J.1
Schluter, A.2
Pedraza, N.3
Iglesias, R.4
Villarroya, F.5
Giralt, M.6
-
10
-
-
80052739107
-
White to brown fat phenotypic switch induced by genetic and environmental activation of a hypothalamic-adipocyte axis
-
Cao L, Choi EY, Liu X, et al. White to brown fat phenotypic switch induced by genetic and environmental activation of a hypothalamic-adipocyte axis. Cell Metab 2011;14:324-338
-
(2011)
Cell Metab
, vol.14
, pp. 324-338
-
-
Cao, L.1
Choi, E.Y.2
Liu, X.3
-
11
-
-
78650945931
-
Prdm16 determines the thermogenic program of subcutaneous white adipose tissue in mice
-
Seale P, Conroe HM, Estall J, et al. Prdm16 determines the thermogenic program of subcutaneous white adipose tissue in mice. J Clin Invest 2011; 121:96-105
-
(2011)
J Clin Invest
, vol.121
, pp. 96-105
-
-
Seale, P.1
Conroe, H.M.2
Estall, J.3
-
12
-
-
84862776702
-
A PGC1-a-dependent myokine that drives brown-fat-like development of white fat and thermogenesis
-
Boström P, Wu J, Jedrychowski MP, et al. A PGC1-a-dependent myokine that drives brown-fat-like development of white fat and thermogenesis. Nature 2012;481:463-468
-
(2012)
Nature
, vol.481
, pp. 463-468
-
-
Boström, P.1
Wu, J.2
Jedrychowski, M.P.3
-
13
-
-
84869497609
-
FNDC5 and irisin in humans: I. Predictors of circulating concentrations in serum and plasma and II. MRNA expression and circulating concentrations in response to weight loss and exercise
-
Huh JY, Panagiotou G, Mougios V, et al. FNDC5 and irisin in humans: I. Predictors of circulating concentrations in serum and plasma and II. mRNA expression and circulating concentrations in response to weight loss and exercise. Metabolism 2012;61:1725-1738
-
(2012)
Metabolism
, vol.61
, pp. 1725-1738
-
-
Huh, J.Y.1
Panagiotou, G.2
Mougios, V.3
-
14
-
-
84879915581
-
Lower circulating irisin is associated with type 2 diabetes mellitus
-
Liu JJ, Wong MD, Toy WC, et al. Lower circulating irisin is associated with type 2 diabetes mellitus. J Diabetes Complications 2013;27:365-369
-
(2013)
J Diabetes Complications
, vol.27
, pp. 365-369
-
-
Liu, J.J.1
Wong, M.D.2
Toy, W.C.3
-
15
-
-
84876736157
-
Serum irisin levels in new-onset type 2 diabetes
-
Choi YK, Kim MK, Bae KH, et al. Serum irisin levels in new-onset type 2 diabetes. Diabetes Res Clin Pract 2013;100:96-101
-
(2013)
Diabetes Res Clin Pract
, vol.100
, pp. 96-101
-
-
Choi, Y.K.1
Kim, M.K.2
Bae, K.H.3
-
16
-
-
84877129604
-
Decrease in irisin in patients with chronic kidney disease
-
Wen MS, Wang CY, Lin SL, Hung KC. Decrease in irisin in patients with chronic kidney disease. PLoS ONE 2013;8:e64025
-
(2013)
PLoS ONE
, vol.8
-
-
Wen, M.S.1
Wang, C.Y.2
Lin, S.L.3
Hung, K.C.4
-
17
-
-
84873512773
-
Expression of the irisin precursor FNDC5 in skeletal muscle correlates with aerobic exercise performance in patients with heart failure
-
Lecker SH, Zavin A, Cao P, et al. Expression of the irisin precursor FNDC5 in skeletal muscle correlates with aerobic exercise performance in patients with heart failure. Circ Heart Fail 2012;5:812-818
-
(2012)
Circ Heart Fail
, vol.5
, pp. 812-818
-
-
Lecker, S.H.1
Zavin, A.2
Cao, P.3
-
18
-
-
77249099832
-
Hepatic FGF21 expression is induced at birth via PPARalpha in response to milk intake and contributes to thermogenic activation of neonatal brown fat
-
Hondares E, Rosell M, Gonzalez FJ, Giralt M, Iglesias R, Villarroya F. Hepatic FGF21 expression is induced at birth via PPARalpha in response to milk intake and contributes to thermogenic activation of neonatal brown fat. Cell Metab 2010;11:206-212
-
(2010)
Cell Metab
, vol.11
, pp. 206-212
-
-
Hondares, E.1
Rosell, M.2
Gonzalez, F.J.3
Giralt, M.4
Iglesias, R.5
Villarroya, F.6
-
19
-
-
84863229962
-
Cardiac natriuretic peptides act via p38 MAPK to induce the brown fat thermogenic program in mouse and human adipocytes
-
Bordicchia M, Liu D, Amri EZ, et al. Cardiac natriuretic peptides act via p38 MAPK to induce the brown fat thermogenic program in mouse and human adipocytes. J Clin Invest 2012;122:1022-1036
-
(2012)
J Clin Invest
, vol.122
, pp. 1022-1036
-
-
Bordicchia, M.1
Liu, D.2
Amri, E.Z.3
-
20
-
-
77955417027
-
Expression, purification, and characterization of recombinant human pancreatic duodenal homeobox-1 protein in Pichia pastoris
-
Li SW, Sun Y, Donelan W, et al. Expression, purification, and characterization of recombinant human pancreatic duodenal homeobox-1 protein in Pichia pastoris. Protein Expr Purif 2010;72:157-161
-
(2010)
Protein Expr Purif
, vol.72
, pp. 157-161
-
-
Li, S.W.1
Sun, Y.2
Donelan, W.3
-
21
-
-
28444488927
-
Primary adipocyte culture: Adipocyte purification methods may lead to a new understanding of adipose tissue growth and development
-
Fernyhough ME, Vierck JL, Hausman GJ, Mir PS, Okine EK, Dodson MV. Primary adipocyte culture: adipocyte purification methods may lead to a new understanding of adipose tissue growth and development. Cytotechnology 2004;46:163-172
-
(2004)
Cytotechnology
, vol.46
, pp. 163-172
-
-
Fernyhough, M.E.1
Vierck, J.L.2
Hausman, G.J.3
Mir, P.S.4
Okine, E.K.5
Dodson, M.V.6
-
23
-
-
0346996806
-
Ligand specific up-regulation of a Renilla reniformis luciferase-tagged, structurally unstable muscarinic M3 chimeric G protein-coupled receptor
-
Zeng FY, McLean AJ, Milligan G, Lerner M, Chalmers DT, Behan DP. Ligand specific up-regulation of a Renilla reniformis luciferase-tagged, structurally unstable muscarinic M3 chimeric G protein-coupled receptor. Mol Pharmacol 2003;64:1474-1484
-
(2003)
Mol Pharmacol
, vol.64
, pp. 1474-1484
-
-
Zeng, F.Y.1
McLean, A.J.2
Milligan, G.3
Lerner, M.4
Chalmers, D.T.5
Behan, D.P.6
-
24
-
-
84864287504
-
Beige adipocytes are a distinct type of thermogenic fat cell in mouse and human
-
Wu J, Boström P, Sparks LM, et al. Beige adipocytes are a distinct type of thermogenic fat cell in mouse and human. Cell 2012;150:366-376
-
(2012)
Cell
, vol.150
, pp. 366-376
-
-
Wu, J.1
Boström, P.2
Sparks, L.M.3
-
25
-
-
84877707122
-
Betatrophin: A hormone that controls pancreatic b cell proliferation
-
Yi P, Park JS, Melton DA. Betatrophin: a hormone that controls pancreatic b cell proliferation. Cell 2013;153:747-758
-
(2013)
Cell
, vol.153
, pp. 747-758
-
-
Yi, P.1
Park, J.S.2
Melton, D.A.3
-
26
-
-
84893053029
-
Irisin and the therapeutic benefits of exercise
-
Spiegelman BM, Korsmeyer SJ. Irisin and the therapeutic benefits of exercise. BMC Proceedings 2012;6(Suppl. 3):O23
-
(2012)
BMC Proceedings
, vol.6
, Issue.SUPPL. 3
-
-
Spiegelman, B.M.1
Korsmeyer, S.J.2
-
27
-
-
84880570314
-
Irisin levels correlate with energy expenditure in a subgroup of humans with energy expenditure greater than predicted by fat free mass
-
Swick A.G., Orena S., O'Connor A. Irisin levels correlate with energy expenditure in a subgroup of humans with energy expenditure greater than predicted by fat free mass. Metabolism 2013;62:1070-1073
-
(2013)
Metabolism
, vol.62
, pp. 1070-1073
-
-
Swick, A.G.1
Orena, S.2
O'connor, A.3
-
28
-
-
67650117727
-
Expression and characterization of recombinant human secretory leukocyte protease inhibitor (SLPI) protein from Pichia pastoris
-
Li Z, Moy A, Sohal K, et al. Expression and characterization of recombinant human secretory leukocyte protease inhibitor (SLPI) protein from Pichia pastoris. Protein Expr Purif 2009;67:175-181
-
(2009)
Protein Expr Purif
, vol.67
, pp. 175-181
-
-
Li, Z.1
Moy, A.2
Sohal, K.3
-
29
-
-
50049122271
-
PRDM16 controls a brown fat/skeletal muscle switch
-
Seale P, Bjork B, Yang W, et al. PRDM16 controls a brown fat/skeletal muscle switch. Nature 2008;454:961-967
-
(2008)
Nature
, vol.454
, pp. 961-967
-
-
Seale, P.1
Bjork, B.2
Yang, W.3
-
30
-
-
77954741222
-
Inducible lineage tracing of Pax7-descendant cells reveals embryonic origin of adult satellite cells
-
Lepper C, Fan CM. Inducible lineage tracing of Pax7-descendant cells reveals embryonic origin of adult satellite cells. Genesis 2010;48: 424-436
-
(2010)
Genesis
, vol.48
, pp. 424-436
-
-
Lepper, C.1
Fan, C.M.2
-
31
-
-
76049130230
-
Recruitment of brown fat and conversion of white into brown adipocytes: Strategies to fight the metabolic complications of obesity?
-
Langin, D. Recruitment of brown fat and conversion of white into brown adipocytes: strategies to fight the metabolic complications of obesity? Biochim Biophys Acta 2010;1801:372-376
-
(2010)
Biochim Biophys Acta
, vol.1801
, pp. 372-376
-
-
Langin, D.1
-
33
-
-
79951560291
-
Between brown and white: Novel aspects of adipocyte differentiation
-
Cinti S. Between brown and white: novel aspects of adipocyte differentiation. Ann Med 2011;43:104-115
-
(2011)
Ann Med
, vol.43
, pp. 104-115
-
-
Cinti, S.1
-
34
-
-
77950226740
-
Chronic peroxisome proliferator-activated receptor gamma (PPARgamma) activation of epididymally derived white adipocyte cultures reveals a population of thermogenically competent, UCP1-containing adipocytes molecularly distinct from classic brown adipocytes
-
Petrovic N, Walden TB, Shabalina IG, Timmons JA, Cannon B, Nedergaard J. Chronic peroxisome proliferator-activated receptor gamma (PPARgamma) activation of epididymally derived white adipocyte cultures reveals a population of thermogenically competent, UCP1-containing adipocytes molecularly distinct from classic brown adipocytes. J Biol Chem 2010;285: 7153-7164
-
(2010)
J Biol Chem
, vol.285
, pp. 7153-7164
-
-
Petrovic, N.1
Walden, T.B.2
Shabalina, I.G.3
Timmons, J.A.4
Cannon, B.5
Nedergaard, J.6
-
35
-
-
78449266620
-
Positive and negative control of Ucp1 gene transcription and the role of b-adrenergic signaling networks
-
Collins S, Yehuda-Shnaidman E, Wang H. Positive and negative control of Ucp1 gene transcription and the role of b-adrenergic signaling networks. Int J Obes (Lond) 2010;34(Suppl. 1):S28-S33
-
(2010)
Int J Obes (Lond)
, vol.34
, Issue.SUPPL. 1
-
-
Collins, S.1
Yehuda-Shnaidman, E.2
Wang, H.3
-
36
-
-
79953210362
-
Regulation of PGC-1a, a nodal regulator of mitochondrial biogenesis
-
Fernandez-Marcos PJ, Auwerx J. Regulation of PGC-1a, a nodal regulator of mitochondrial biogenesis. Am J Clin Nutr 2011;93:884S-90
-
(2011)
Am J Clin Nutr
, vol.93
-
-
Fernandez-Marcos, P.J.1
Auwerx, J.2
-
37
-
-
84877147751
-
Myostatin knockout drives browning of white adipose tissue through activating the AMPK-PGC1a-Fndc5 pathway in muscle
-
Shan T, Liang X, Bi P, Kuang S. Myostatin knockout drives browning of white adipose tissue through activating the AMPK-PGC1a-Fndc5 pathway in muscle. FASEB J 2013;27:1981-1989
-
(2013)
FASEB J
, vol.27
, pp. 1981-1989
-
-
Shan, T.1
Liang, X.2
Bi, P.3
Kuang, S.4
-
38
-
-
48449094498
-
AMPK and PPARdelta agonists are exercise mimetics
-
Narkar VA, Downes M, Yu RT, et al. AMPK and PPARdelta agonists are exercise mimetics. Cell 2008;134:405-415
-
(2008)
Cell
, vol.134
, pp. 405-415
-
-
Narkar, V.A.1
Downes, M.2
Yu, R.T.3
|