메뉴 건너뛰기




Volumn 14, Issue 2, 2011, Pages 242-253

Cardiotrophin-1 is a key regulator of glucose and lipid metabolism

Author keywords

[No Author keywords available]

Indexed keywords

CARDIOTROPHIN 1; GLUCOSE; GLYCOPROTEIN GP 130; INSULIN; LIPID;

EID: 79960955885     PISSN: 15504131     EISSN: 19327420     Source Type: Journal    
DOI: 10.1016/j.cmet.2011.05.013     Document Type: Article
Times cited : (103)

References (49)
  • 1
    • 7044272602 scopus 로고    scopus 로고
    • Ax15 alters energy homeostasis, decreases body weight, and improves metabolic control in diet-induced obese and UCP1-DTA mice
    • DOI 10.2337/diabetes.53.11.2787
    • Blüher, S., Moschos, S., Bullen, J., Jr., Kokkotou, E., Maratos-Flier, E., Wiegand, S.J., Sleeman, M.W., and Mantzoros, C.S. (2004). Ciliary neurotrophic factorAx15 alters energy homeostasis, decreases body weight, and improves metabolic control in diet-induced obese and UCP1-DTA mice. Diabetes 53, 2787-2796. (Pubitemid 39425903)
    • (2004) Diabetes , vol.53 , Issue.11 , pp. 2787-2796
    • Bluher, S.1    Moschos, S.2    Bullen Jr., J.3    Kokkotou, E.4    Maratos-Flier, E.5    Wiegand, S.J.6    Sleemann, M.W.7    Mantzoros, C.S.8
  • 3
    • 38849199866 scopus 로고    scopus 로고
    • Mitochondrial dysfunction results from oxidative stress in the skeletal muscle of diet-induced insulin-resistant mice
    • Bonnard, C., Durand, A., Peyrol, S., Chanseaume, E., Chauvin, M.A., Morio, B., Vidal, H., and Rieusset, J. (2008). Mitochondrial dysfunction results from oxidative stress in the skeletal muscle of diet-induced insulin-resistant mice. J. Clin. Invest. 118, 789-800.
    • (2008) J. Clin. Invest. , vol.118 , pp. 789-800
    • Bonnard, C.1    Durand, A.2    Peyrol, S.3    Chanseaume, E.4    Chauvin, M.A.5    Morio, B.6    Vidal, H.7    Rieusset, J.8
  • 5
    • 0038730615 scopus 로고    scopus 로고
    • Protection against liver damage by cardiotrophin-1: A hepatocyte survival factor up-regulated in the regenerating liver in rats
    • DOI 10.1016/S0016-5085(03)00698-X
    • Bustos, M., Beraza, N., Lasarte, J.J., Baixeras, E., Alzuguren, P., Bordet, T., and Prieto, J. (2003). Protection against liver damage by cardiotrophin-1: a hepatocyte survival factor up-regulated in the regenerating liver in rats. Gastroenterology 125, 192-201. (Pubitemid 36799119)
    • (2003) Gastroenterology , vol.125 , Issue.1 , pp. 192-201
    • Bustos, M.1    Beraza, N.2    Lasarte, J.-J.3    Baixeras, E.4    Alzuguren, P.5    Bordet, T.6    Prieto, J.7
  • 7
    • 33646582664 scopus 로고    scopus 로고
    • Hypothalamic mTOR signaling regulates food intake
    • DOI 10.1126/science.1124147
    • Cota, D., Proulx, K., Smith, K.A., Kozma, S.C., Thomas, G., Woods, S.C., and Seeley, R.J. (2006). Hypothalamic mTOR signaling regulates food intake. Science 312, 927-930. (Pubitemid 43727328)
    • (2006) Science , vol.312 , Issue.5775 , pp. 927-930
    • Cota, D.1    Proulx, K.2    Blake, S.K.A.3    Kozma, S.C.4    Thomas, G.5    Woods, S.C.6    Seeley, R.J.7
  • 8
    • 49049114337 scopus 로고    scopus 로고
    • The role of hypothalamic mammalian target of rapamycin complex 1 signaling in diet-induced obesity
    • Cota, D., Matter, E.K., Woods, S.C., and Seeley, R.J. (2008). The role of hypothalamic mammalian target of rapamycin complex 1 signaling in diet-induced obesity. J. Neurosci. 28, 7202-7208.
    • (2008) J. Neurosci. , vol.28 , pp. 7202-7208
    • Cota, D.1    Matter, E.K.2    Woods, S.C.3    Seeley, R.J.4
  • 9
    • 42449158932 scopus 로고    scopus 로고
    • Metabolic remodeling in adipocytes promotes ciliary neurotrophic factor-mediated fat loss in obesity
    • DOI 10.1210/en.2007-1447
    • Crowe, S., Turpin, S.M., Ke, F., Kemp, B.E., and Watt, M.J. (2008). Metabolic remodeling in adipocytes promotes ciliary neurotrophic factor-mediated fat loss in obesity. Endocrinology 149, 2546-2556. (Pubitemid 351574491)
    • (2008) Endocrinology , vol.149 , Issue.5 , pp. 2546-2556
    • Crowe, S.1    Turpin, S.M.2    Ke, F.3    Kemp, B.E.4    Watt, M.J.5
  • 10
    • 3042739678 scopus 로고    scopus 로고
    • Lipid and carbohydrate metabolism in mice with a targeted mutation in the IL-6 gene: Absence of development of age-related obesity
    • Di Gregorio, G.B., Hensley, L., Lu, T., Ranganathan, G., and Kern, P.A. (2004). Lipid and carbohydrate metabolism in mice with a targeted mutation in the IL-6 gene: absence of development of age-related obesity. Am. J. Physiol. Endocrinol. Metab. 287, E182-E187.
    • (2004) Am. J. Physiol. Endocrinol. Metab. , vol.287
    • Di Gregorio, G.B.1    Hensley, L.2    Lu, T.3    Ranganathan, G.4    Kern, P.A.5
  • 12
    • 34147159710 scopus 로고    scopus 로고
    • gp130 receptor ligands as potential therapeutic targets for obesity
    • Febbraio, M.A. (2007). gp130 receptor ligands as potential therapeutic targets for obesity. J. Clin. Invest. 117, 841-849.
    • (2007) J. Clin. Invest. , vol.117 , pp. 841-849
    • Febbraio, M.A.1
  • 13
    • 3042721664 scopus 로고    scopus 로고
    • Interleukin-6 is a novel factor mediating glucose homeostasis during skeletal muscle contraction
    • DOI 10.2337/diabetes.53.7.1643
    • Febbraio, M.A., Hiscock, N., Sacchetti, M., Fischer, C.P., and Pedersen, B.K. (2004). Interleukin-6 is a novel factor mediating glucose homeostasis during skeletal muscle contraction. Diabetes 53, 1643-1648. (Pubitemid 38864744)
    • (2004) Diabetes , vol.53 , Issue.7 , pp. 1643-1648
    • Febbraio, M.A.1    Hiscock, N.2    Saccheti, M.3    Fischer, C.P.4    Pedersen, B.K.5
  • 15
    • 50049091255 scopus 로고    scopus 로고
    • AMPK: A key regulator of energy balance in the single cell and the whole organism
    • Lond.
    • Hardie, D.G. (2008). AMPK: a key regulator of energy balance in the single cell and the whole organism. Int. J. Obes. (Lond.) 32 (Suppl 4), S7-S12.
    • (2008) Int. J. Obes. , vol.32 , Issue.SUPPL. 4
    • Hardie, D.G.1
  • 16
    • 4143052910 scopus 로고    scopus 로고
    • Skeletal myocytes are a source of interleukin-6 mRNA expression and protein release during contraction: Evidence of fiber type specificity
    • DOI 10.1096/fj.03-1259fje
    • Hiscock, N., Chan, M.H., Bisucci, T., Darby, I.A., and Febbraio, M.A. (2004). Skeletal myocytes are a source of interleukin-6 mRNA expression and protein release during contraction: evidence of fiber type specificity. FASEB J. 18, 992-994. (Pubitemid 39561502)
    • (2004) FASEB Journal , vol.18 , Issue.9 , pp. 992-994
    • Hiscock, N.1    Chan, M.H.S.2    Bisucci, T.3    Darby, I.A.4    Febbraio, M.A.5
  • 17
    • 72649089588 scopus 로고    scopus 로고
    • Acute or chronic upregulation of mitochondrial fatty acid oxidation has no net effect on whole-body energy expenditure or adiposity
    • Hoehn, K.L., Turner, N., Swarbrick, M.M., Wilks, D., Preston, E., Phua, Y., Joshi, H., Furler, S.M., Larance, M., Hegarty, B.D., et al. (2010). Acute or chronic upregulation of mitochondrial fatty acid oxidation has no net effect on whole-body energy expenditure or adiposity. Cell Metab. 11, 70-76.
    • (2010) Cell Metab. , vol.11 , pp. 70-76
    • Hoehn, K.L.1    Turner, N.2    Swarbrick, M.M.3    Wilks, D.4    Preston, E.5    Phua, Y.6    Joshi, H.7    Furler, S.M.8    Larance, M.9    Hegarty, B.D.10
  • 18
    • 33845878554 scopus 로고    scopus 로고
    • Cardiotrophin-1 defends the liver against ischemia-reperfusion injury and mediates the protective effect of ischemic preconditioning
    • Iñiguez, M., Berasain, C., Martinez-Ansó, E., Bustos, M., Fortes, P., Pennica, D., Avila, M.A., and Prieto, J. (2006). Cardiotrophin-1 defends the liver against ischemia-reperfusion injury and mediates the protective effect of ischemic preconditioning. J. Exp. Med. 203, 2809-2815.
    • (2006) J. Exp. Med. , vol.203 , pp. 2809-2815
    • Iñiguez, M.1    Berasain, C.2    Martinez-Ansó, E.3    Bustos, M.4    Fortes, P.5    Pennica, D.6    Avila, M.A.7    Prieto, J.8
  • 20
    • 34347219137 scopus 로고    scopus 로고
    • Adipose triglyceride lipase and hormone-sensitive lipase protein expression is decreased in the obese insulin-resistant state
    • Jocken, J.W., Langin, D., Smit, E., Saris, W.H., Valle, C., Hul, G.B., Holm, C., Arner, P., and Blaak, E.E. (2007). Adipose triglyceride lipase and hormone-sensitive lipase protein expression is decreased in the obese insulin-resistant state. J. Clin. Endocrinol. Metab. 92, 2292-2299.
    • (2007) J. Clin. Endocrinol. Metab. , vol.92 , pp. 2292-2299
    • Jocken, J.W.1    Langin, D.2    Smit, E.3    Saris, W.H.4    Valle, C.5    Hul, G.B.6    Holm, C.7    Arner, P.8    Blaak, E.E.9
  • 21
    • 33644755633 scopus 로고    scopus 로고
    • Interleukin-6 and diabetes: The good, the bad, or the indifferent?
    • Kristiansen, O.P., and Mandrup-Poulsen, T. (2005). Interleukin-6 and diabetes: the good, the bad, or the indifferent? Diabetes 54 (Suppl 2), S114-S124.
    • (2005) Diabetes , vol.54 , Issue.SUPPL. 2
    • Kristiansen, O.P.1    Mandrup-Poulsen, T.2
  • 23
    • 33947362493 scopus 로고    scopus 로고
    • Cardiotrophin-1 is an essential factor in the natural defense of the liver against apoptosis
    • DOI 10.1002/hep.21508
    • Marquès, J.M., Belza, I., Holtmann, B., Pennica, D., Prieto, J., and Bustos, M. (2007). Cardiotrophin-1 is an essential factor in the natural defense of the liver against apoptosis. Hepatology 45, 639-648. (Pubitemid 46450615)
    • (2007) Hepatology , vol.45 , Issue.3 , pp. 639-648
    • Marques, J.M.1    Belza, I.2    Holtmann, B.3    Pennica, D.4    Prieto, J.5    Bustos, M.6
  • 24
    • 0027484249 scopus 로고
    • Disruption of the CNTF gene results in motor neuron degeneration
    • DOI 10.1038/365027a0
    • Masu, Y., Wolf, E., Holtmann, B., Sendtner, M., Brem, G., and Thoenen, H. (1993). Disruption of the CNTF gene results in motor neuron degeneration. Nature 365, 27-32. (Pubitemid 23305564)
    • (1993) Nature , vol.365 , Issue.6441 , pp. 27-32
    • Masu, Y.1    Wolf, E.2    Holtmann, B.3    Sendtner, M.4    Brem, G.5    Thoenen, H.6
  • 25
    • 0037122766 scopus 로고    scopus 로고
    • Leptin stimulates fatty-acid oxidation by activating AMP-activated protein kinase
    • DOI 10.1038/415339a
    • Minokoshi, Y., Kim, Y.B., Peroni, O.D., Fryer, L.G., Müller, C., Carling, D., and Kahn, B.B. (2002). Leptin stimulates fatty-acid oxidation by activating AMPactivated protein kinase. Nature 415, 339-343. (Pubitemid 34087557)
    • (2002) Nature , vol.415 , Issue.6869 , pp. 339-343
    • Minokoshi, Y.1    Kim, Y.-B.2    Peroni, O.D.3    Fryer, L.G.D.4    Muller, C.5    Carling, D.6    Kahn, B.B.7
  • 28
    • 24344480561 scopus 로고    scopus 로고
    • Plasma cardiotrophin-1 is elevated in human hypertension and stimulated by ventricular stretch
    • Pemberton, C.J., Raudsepp, S.D., Yandle, T.G., Cameron, V.A., and Richards, A.M. (2005). Plasma cardiotrophin-1 is elevated in human hypertension and stimulated by ventricular stretch. Cardiovasc. Res. 68, 109-117.
    • (2005) Cardiovasc. Res. , vol.68 , pp. 109-117
    • Pemberton, C.J.1    Raudsepp, S.D.2    Yandle, T.G.3    Cameron, V.A.4    Richards, A.M.5
  • 32
    • 0033305464 scopus 로고    scopus 로고
    • Effects of intravenously infused leptin on insulin sensitivity and on the expression of uncoupling proteins in brown adipose tissue
    • Rouru, J., Cusin, I., Zakrzewska, K.E., Jeanrenaud, B., and Rohner-Jeanrenaud, F. (1999). Effects of intravenously infused leptin on insulin sensitivity and on the expression of uncoupling proteins in brown adipose tissue. Endocrinology 140, 3688-3692. (Pubitemid 30645424)
    • (1999) Endocrinology , vol.140 , Issue.8 , pp. 3688-3692
    • Rouru, J.1    Cusin, I.2    Zakrzewska, K.E.3    Jeanrenaud, B.4    Rohner-Jeanrenaud, F.5
  • 34
    • 0034668926 scopus 로고    scopus 로고
    • Production of interleukin-6 in contracting human skeletal muscles can account for the exercise-induced increase in plasma interleukin-6
    • Steensberg, A., van Hall, G., Osada, T., Sacchetti, M., Saltin, B., and Klarlund Pedersen, B. (2000). Production of interleukin-6 in contracting human skeletal muscles can account for the exercise-induced increase in plasma interleukin-6. J. Physiol. 529, 237-242.
    • (2000) J. Physiol. , vol.529 , pp. 237-242
    • Steensberg, A.1    Van Hall, G.2    Osada, T.3    Sacchetti, M.4    Saltin, B.5    Klarlund Pedersen, B.6
  • 35
    • 33746037555 scopus 로고    scopus 로고
    • Ciliary neurotrophic factor suppresses hypothalamic AMP-kinase signaling in leptin-resistant obese mice
    • DOI 10.1210/en.2005-1587
    • Steinberg, G.R., Watt, M.J., Fam, B.C., Proietto, J., Andrikopoulos, S., Allen, A.M., Febbraio, M.A., and Kemp, B.E. (2006). Ciliary neurotrophic factor suppresses hypothalamic AMP-kinase signaling in leptin-resistant obese mice. Endocrinology 147, 3906-3914. (Pubitemid 44079396)
    • (2006) Endocrinology , vol.147 , Issue.8 , pp. 3906-3914
    • Steinberg, G.R.1    Watt, M.J.2    Fam, B.C.3    Proietto, J.4    Andrikopoulos, S.5    Allen, A.M.6    Febbraio, M.A.7    Kemp, B.E.8
  • 36
    • 0035947614 scopus 로고    scopus 로고
    • A novel role of neuregulin in skeletal muscle. Neuregulin stimulates glucose uptake, glucose transporter translocation, and transporter expression in muscle cells
    • Suárez, E., Bach, D., Cadefau, J., Palacin, M., Zorzano, A., and Gumá, A. (2001). A novel role of neuregulin in skeletal muscle. Neuregulin stimulates glucose uptake, glucose transporter translocation, and transporter expression in muscle cells. J. Biol. Chem. 276, 18257-18264.
    • (2001) J. Biol. Chem. , vol.276 , pp. 18257-18264
    • Suárez, E.1    Bach, D.2    Cadefau, J.3    Palacin, M.4    Zorzano, A.5    Gumá, A.6
  • 38
    • 33748992313 scopus 로고    scopus 로고
    • Adipocytokines: Mediators linking adipose tissue, inflammation and immunity
    • Tilg, H., and Moschen, A.R. (2006). Adipocytokines: mediators linking adipose tissue, inflammation and immunity. Nat. Rev. Immunol. 6, 772-783.
    • (2006) Nat. Rev. Immunol. , vol.6 , pp. 772-783
    • Tilg, H.1    Moschen, A.R.2
  • 39
    • 34547588219 scopus 로고    scopus 로고
    • Excess lipid availability increases mitochondrial fatty acid oxidative capacity in muscle: Evidence against a role for reduced fatty acid oxidation in lipid-induced insulin resistance in rodents
    • DOI 10.2337/db07-0093
    • Turner, N., Bruce, C.R., Beale, S.M., Hoehn, K.L., So, T., Rolph, M.S., and Cooney, G.J. (2007). Excess lipid availability increases mitochondrial fatty acid oxidative capacity in muscle: evidence against a role for reduced fatty acid oxidation in lipid-induced insulin resistance in rodents. Diabetes 56, 2085-2092. (Pubitemid 47195821)
    • (2007) Diabetes , vol.56 , Issue.8 , pp. 2085-2092
    • Turner, N.1    Bruce, C.R.2    Beale, S.M.3    Hoehn, K.L.4    So, T.5    Rolph, M.S.6    Cooney, G.J.7
  • 40
    • 8744297386 scopus 로고    scopus 로고
    • Desnutrin, an adipocyte gene encoding a novel patatin domain-containing protein, is induced by fasting and glucocorticoids: Ectopic expression of desnutrin increases triglyceride hydrolysis
    • Villena, J.A., Roy, S., Sarkadi-Nagy, E., Kim, K.H., and Sul, H.S. (2004). Desnutrin, an adipocyte gene encoding a novel patatin domain-containing protein, is induced by fasting and glucocorticoids: ectopic expression of desnutrin increases triglyceride hydrolysis. J. Biol. Chem. 279, 47066-47075.
    • (2004) J. Biol. Chem. , vol.279 , pp. 47066-47075
    • Villena, J.A.1    Roy, S.2    Sarkadi-Nagy, E.3    Kim, K.H.4    Sul, H.S.5
  • 46
    • 0036064261 scopus 로고    scopus 로고
    • Glycogen-dependent effects of 5-aminoimidazole-4-carboxamide (AICA)-riboside on AMP-activated protein kinase and glycogen synthase activities in rat skeletal muscle
    • Wojtaszewski, J.F., Jørgensen, S.B., Hellsten, Y., Hardie, D.G., and Richter, E.A. (2002). Glycogen-dependent effects of 5-aminoimidazole-4- carboxamide (AICA)-riboside on AMP-activated protein kinase and glycogen synthase activities in rat skeletal muscle. Diabetes 51, 284-292. (Pubitemid 34764782)
    • (2002) Diabetes , vol.51 , Issue.2 , pp. 284-292
    • Wojtaszewski, J.F.P.1    Jorgensen, S.B.2    Hellsten, Y.3    Grahame, H.D.4    Richter, E.A.5
  • 47
    • 39049179892 scopus 로고    scopus 로고
    • Effects of acute exercise and training on insulin action and sensitivity: Focus on molecular mechanisms in muscle
    • Wojtaszewski, J.F., and Richter, E.A. (2006). Effects of acute exercise and training on insulin action and sensitivity: focus on molecular mechanisms in muscle. Essays Biochem. 42, 31-46.
    • (2006) Essays Biochem. , vol.42 , pp. 31-46
    • Wojtaszewski, J.F.1    Richter, E.A.2
  • 48
    • 59449097943 scopus 로고    scopus 로고
    • Basal lipolysis, not the degree of insulin resistance, differentiates large from small isolated adipocytes in high-fat fed mice
    • Wueest, S., Rapold, R.A., Rytka, J.M., Schoenle, E.J., and Konrad, D. (2009). Basal lipolysis, not the degree of insulin resistance, differentiates large from small isolated adipocytes in high-fat fed mice. Diabetologia 52, 541-546.
    • (2009) Diabetologia , vol.52 , pp. 541-546
    • Wueest, S.1    Rapold, R.A.2    Rytka, J.M.3    Schoenle, E.J.4    Konrad, D.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.