-
1
-
-
84862776702
-
A PGC1-alpha-dependent myokine that drives brown-fat-like development of white fat and thermogenesis
-
Bostrom P, Wu J, Jedrychowski MP, Korde A, Ye L, et al. (2012) A PGC1-alpha-dependent myokine that drives brown-fat-like development of white fat and thermogenesis. Nature 481: 463-468.
-
(2012)
Nature
, vol.481
, pp. 463-468
-
-
Bostrom, P.1
Wu, J.2
Jedrychowski, M.P.3
Korde, A.4
Ye, L.5
-
2
-
-
64349123664
-
Functional brown adipose tissue in healthy adults
-
Virtanen KA, Lidell ME, Orava J, Heglind M, Westergren R, et al. (2009) Functional brown adipose tissue in healthy adults. N Engl J Med 360: 1518-1525.
-
(2009)
N Engl J Med
, vol.360
, pp. 1518-1525
-
-
Virtanen, K.A.1
Lidell, M.E.2
Orava, J.3
Heglind, M.4
Westergren, R.5
-
3
-
-
64349105205
-
Identification and importance of brown adipose tissue in adult humans
-
Cypess AM, Lehman S, Williams G, Tal I, Rodman D, et al. (2009) Identification and importance of brown adipose tissue in adult humans. N Engl J Med 360: 1509-1517.
-
(2009)
N Engl J Med
, vol.360
, pp. 1509-1517
-
-
Cypess, A.M.1
Lehman, S.2
Williams, G.3
Tal, I.4
Rodman, D.5
-
5
-
-
67650242165
-
High incidence of metabolically active brown adipose tissue in healthy adult humans: effects of cold exposure and adiposity
-
Saito M, Okamatsu-Ogura Y, Matsushita M, Watanabe K, Yoneshiro T, et al. (2009) High incidence of metabolically active brown adipose tissue in healthy adult humans: effects of cold exposure and adiposity. Diabetes 58: 1526-1531.
-
(2009)
Diabetes
, vol.58
, pp. 1526-1531
-
-
Saito, M.1
Okamatsu-Ogura, Y.2
Matsushita, M.3
Watanabe, K.4
Yoneshiro, T.5
-
6
-
-
78650676545
-
Brown adipose tissue, whole-body energy expenditure, and thermogenesis in healthy adult men
-
Yoneshiro T, Aita S, Matsushita M, Kameya T, Nakada K, et al. (2011) Brown adipose tissue, whole-body energy expenditure, and thermogenesis in healthy adult men. Obesity (Silver Spring) 19: 13-16.
-
(2011)
Obesity (Silver Spring)
, vol.19
, pp. 13-16
-
-
Yoneshiro, T.1
Aita, S.2
Matsushita, M.3
Kameya, T.4
Nakada, K.5
-
7
-
-
77950221998
-
Human brown adipose tissue
-
Enerback S, (2010) Human brown adipose tissue. Cell Metab 11: 248-252.
-
(2010)
Cell Metab
, vol.11
, pp. 248-252
-
-
Enerback, S.1
-
8
-
-
84865512723
-
Is irisin a human exercise gene?
-
Timmons JA, Baar K, Davidsen PK, Atherton PJ, (2012) Is irisin a human exercise gene? Nature 488: E9-10.
-
(2012)
Nature
, vol.488
, pp. 9-10
-
-
Timmons, J.A.1
Baar, K.2
Davidsen, P.K.3
Atherton, P.J.4
-
9
-
-
0032549811
-
A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis
-
Puigserver P, Wu Z, Park CW, Graves R, Wright M, et al. (1998) A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis. Cell 92: 829-839.
-
(1998)
Cell
, vol.92
, pp. 829-839
-
-
Puigserver, P.1
Wu, Z.2
Park, C.W.3
Graves, R.4
Wright, M.5
-
10
-
-
47949104798
-
The role of exercise and PGC1alpha in inflammation and chronic disease
-
Handschin C, Spiegelman BM, (2008) The role of exercise and PGC1alpha in inflammation and chronic disease. Nature 454: 463-469.
-
(2008)
Nature
, vol.454
, pp. 463-469
-
-
Handschin, C.1
Spiegelman, B.M.2
-
11
-
-
73949099327
-
Increased muscle PGC-1alpha expression protects from sarcopenia and metabolic disease during aging
-
Wenz T, Rossi SG, Rotundo RL, Spiegelman BM, Moraes CT, (2009) Increased muscle PGC-1alpha expression protects from sarcopenia and metabolic disease during aging. Proc Natl Acad Sci U S A 106: 20405-20410.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 20405-20410
-
-
Wenz, T.1
Rossi, S.G.2
Rotundo, R.L.3
Spiegelman, B.M.4
Moraes, C.T.5
-
12
-
-
0014177607
-
Self-starvation of rats living in activity wheels on a restricted feeding schedule
-
Routtenberg A, Kuznesof AW, (1967) Self-starvation of rats living in activity wheels on a restricted feeding schedule. J Comp Physiol Psychol 64: 414-421.
-
(1967)
J Comp Physiol Psychol
, vol.64
, pp. 414-421
-
-
Routtenberg, A.1
Kuznesof, A.W.2
-
13
-
-
77956685565
-
Peripheral leptin and ghrelin receptors are regulated in a tissue-specific manner in activity-based anorexia
-
Pardo M, Roca-Rivada A, Al-Massadi O, Seoane LM, Camina JP, et al. (2010) Peripheral leptin and ghrelin receptors are regulated in a tissue-specific manner in activity-based anorexia. Peptides 31: 1912-1919.
-
(2010)
Peptides
, vol.31
, pp. 1912-1919
-
-
Pardo, M.1
Roca-Rivada, A.2
Al-Massadi, O.3
Seoane, L.M.4
Camina, J.P.5
-
14
-
-
79957664139
-
Secretome analysis of rat adipose tissues shows location-specific roles for each depot type
-
Roca-Rivada A, Alonso J, Al-Massadi O, Castelao C, Peinado JR, et al. (2011) Secretome analysis of rat adipose tissues shows location-specific roles for each depot type. J Proteomics 74: 1068-1079.
-
(2011)
J Proteomics
, vol.74
, pp. 1068-1079
-
-
Roca-Rivada, A.1
Alonso, J.2
Al-Massadi, O.3
Castelao, C.4
Peinado, J.R.5
-
15
-
-
34247352515
-
Characterization of the human visceral adipose tissue secretome
-
Alvarez-Llamas G, Szalowska E, de Vries MP, Weening D, Landman K, et al. (2007) Characterization of the human visceral adipose tissue secretome. Mol Cell Proteomics 6: 589-600.
-
(2007)
Mol Cell Proteomics
, vol.6
, pp. 589-600
-
-
Alvarez-Llamas, G.1
Szalowska, E.2
de Vries, M.P.3
Weening, D.4
Landman, K.5
-
16
-
-
0016178461
-
An established pre-adipose cell line and its differentiation in culture
-
Green H, Meuth M, (1974) An established pre-adipose cell line and its differentiation in culture. Cell 3: 127-133.
-
(1974)
Cell
, vol.3
, pp. 127-133
-
-
Green, H.1
Meuth, M.2
-
17
-
-
77956854293
-
Age, sex, and lactating status regulate ghrelin secretion and GOAT mRNA levels from isolated rat stomach
-
Al-Massadi O, Crujeiras AB, Gonzalez RC, Pardo M, Dieguez C, et al. (2010) Age, sex, and lactating status regulate ghrelin secretion and GOAT mRNA levels from isolated rat stomach. Am J Physiol Endocrinol Metab 299: E341-350.
-
(2010)
Am J Physiol Endocrinol Metab
, vol.299
-
-
Al-Massadi, O.1
Crujeiras, A.B.2
Gonzalez, R.C.3
Pardo, M.4
Dieguez, C.5
-
18
-
-
84865545283
-
Muscle tissue as an endocrine organ: Comparative secretome profiling of slow-oxidative and fast-glycolytic rat muscle explants and its variation with exercise
-
Roca-Rivada A, Al-Massadi O, Castelao C, Senin LL, Alonso J, et al. (2012) Muscle tissue as an endocrine organ: Comparative secretome profiling of slow-oxidative and fast-glycolytic rat muscle explants and its variation with exercise. J Proteomics 75: 5414-5425.
-
(2012)
J Proteomics
, vol.75
, pp. 5414-5425
-
-
Roca-Rivada, A.1
Al-Massadi, O.2
Castelao, C.3
Senin, L.L.4
Alonso, J.5
-
19
-
-
55949119252
-
Muscle as an endocrine organ: focus on muscle-derived interleukin-6
-
Pedersen BK, Febbraio MA, (2008) Muscle as an endocrine organ: focus on muscle-derived interleukin-6. Physiol Rev 88: 1379-1406.
-
(2008)
Physiol Rev
, vol.88
, pp. 1379-1406
-
-
Pedersen, B.K.1
Febbraio, M.A.2
-
20
-
-
58149506718
-
The role of fat topology in the risk of disease
-
Matsuzawa Y, (2008) The role of fat topology in the risk of disease. Int J Obes (Lond) 32Suppl 7: S83-92.
-
(2008)
Int J Obes (Lond)
, vol.32
-
-
Matsuzawa, Y.1
-
21
-
-
77954201905
-
Review on leptin and adiponectin responses and adaptations to acute and chronic exercise
-
Bouassida A, Chamari K, Zaouali M, Feki Y, Zbidi A, et al. (2010) Review on leptin and adiponectin responses and adaptations to acute and chronic exercise. Br J Sports Med 44: 620-630.
-
(2010)
Br J Sports Med
, vol.44
, pp. 620-630
-
-
Bouassida, A.1
Chamari, K.2
Zaouali, M.3
Feki, Y.4
Zbidi, A.5
-
22
-
-
84858043988
-
Irisin, turning up the heat
-
Villarroya F, (2012) Irisin, turning up the heat. Cell Metab 15: 277-278.
-
(2012)
Cell Metab
, vol.15
, pp. 277-278
-
-
Villarroya, F.1
-
23
-
-
84860766479
-
From white to brown fat through the PGC-1α-dependent myokine irisin: implications for diabetes and obesity
-
Castillo-Quan J, (2012) From white to brown fat through the PGC-1α-dependent myokine irisin: implications for diabetes and obesity. Dis Model Mech 5: 293-295.
-
(2012)
Dis Model Mech
, vol.5
, pp. 293-295
-
-
Castillo-Quan, J.1
-
24
-
-
84859507081
-
Medicine. Irisin, light my fire
-
Kelly DP, (2012) Medicine. Irisin, light my fire. Science 336: 42-43.
-
(2012)
Science
, vol.336
, pp. 42-43
-
-
Kelly, D.P.1
-
25
-
-
84864283300
-
Muscles, exercise and obesity: skeletal muscle as a secretory organ
-
Pedersen BK, Febbraio MA, (2012) Muscles, exercise and obesity: skeletal muscle as a secretory organ. Nat Rev Endocrinol 8 (8): 457-465.
-
(2012)
Nat Rev Endocrinol
, vol.8
, Issue.8
, pp. 457-465
-
-
Pedersen, B.K.1
Febbraio, M.A.2
-
26
-
-
84865314974
-
Irisin: a new potential hormonal target for treatment of obesity and type II diabetes
-
Sanchis-Gomar F, Lippi G, Mayero S, Perez-Quilis C, Garcia-Gimenez JL, (2012) Irisin: a new potential hormonal target for treatment of obesity and type II diabetes. J Diabetes 4 (3): 196.
-
(2012)
J Diabetes
, vol.4
, Issue.3
, pp. 196
-
-
Sanchis-Gomar, F.1
Lippi, G.2
Mayero, S.3
Perez-Quilis, C.4
Garcia-Gimenez, J.L.5
-
27
-
-
84858705567
-
Basic research: Irisin-behind the benefits of exercise
-
Cunha A, (2012) Basic research: Irisin-behind the benefits of exercise. Nat Rev Endocrinol 8: 195.
-
(2012)
Nat Rev Endocrinol
, vol.8
, pp. 195
-
-
Cunha, A.1
-
28
-
-
34547217974
-
Biomarker discovery from uveal melanoma secretomes: identification of gp100 and cathepsin D in patient serum
-
Pardo M, Garcia A, Antrobus R, Blanco MJ, Dwek RA, et al. (2007) Biomarker discovery from uveal melanoma secretomes: identification of gp100 and cathepsin D in patient serum. J Proteome Res 6: 2802-2811.
-
(2007)
J Proteome Res
, vol.6
, pp. 2802-2811
-
-
Pardo, M.1
Garcia, A.2
Antrobus, R.3
Blanco, M.J.4
Dwek, R.A.5
-
29
-
-
34247133868
-
Approaches to the study of the cell secretome
-
Hathout Y, (2007) Approaches to the study of the cell secretome. Expert Rev Proteomics 4: 239-248.
-
(2007)
Expert Rev Proteomics
, vol.4
, pp. 239-248
-
-
Hathout, Y.1
-
30
-
-
73449125521
-
Proteomic identification of multitasking proteins in unexpected locations complicates drug targeting
-
Butler GS, Overall CM, (2009) Proteomic identification of multitasking proteins in unexpected locations complicates drug targeting. Nat Rev Drug Discov 8: 935-948.
-
(2009)
Nat Rev Drug Discov
, vol.8
, pp. 935-948
-
-
Butler, G.S.1
Overall, C.M.2
-
31
-
-
20944436798
-
Human muscle gene expression responses to endurance training provide a novel perspective on Duchenne muscular dystrophy
-
Timmons JA, Larsson O, Jansson E, Fischer H, Gustafsson T, et al. (2005) Human muscle gene expression responses to endurance training provide a novel perspective on Duchenne muscular dystrophy. Faseb J 19: 750-760.
-
(2005)
Faseb J
, vol.19
, pp. 750-760
-
-
Timmons, J.A.1
Larsson, O.2
Jansson, E.3
Fischer, H.4
Gustafsson, T.5
-
32
-
-
77149161091
-
Gene expression of PPARgamma and PGC-1alpha in human omental and subcutaneous adipose tissues is related to insulin resistance markers and mediates beneficial effects of physical training
-
Ruschke K, Fishbein L, Dietrich A, Kloting N, Tonjes A, et al. (2010) Gene expression of PPARgamma and PGC-1alpha in human omental and subcutaneous adipose tissues is related to insulin resistance markers and mediates beneficial effects of physical training. Eur J Endocrinol 162: 515-523.
-
(2010)
Eur J Endocrinol
, vol.162
, pp. 515-523
-
-
Ruschke, K.1
Fishbein, L.2
Dietrich, A.3
Kloting, N.4
Tonjes, A.5
-
33
-
-
34248581989
-
Disordered lipid metabolism and the pathogenesis of insulin resistance
-
Savage DB, Petersen KF, Shulman GI, (2007) Disordered lipid metabolism and the pathogenesis of insulin resistance. Physiol Rev 87: 507-520.
-
(2007)
Physiol Rev
, vol.87
, pp. 507-520
-
-
Savage, D.B.1
Petersen, K.F.2
Shulman, G.I.3
-
36
-
-
74049159942
-
Subcutaneous and visceral adipose tissue: structural and functional differences
-
Ibrahim MM, (2010) Subcutaneous and visceral adipose tissue: structural and functional differences. Obes Rev 11: 11-18.
-
(2010)
Obes Rev
, vol.11
, pp. 11-18
-
-
Ibrahim, M.M.1
-
37
-
-
78449291034
-
Brown fat thermogenesis and body weight regulation in mice: relevance to humans
-
Kozak LP, Koza RA, Anunciado-Koza R, (2010) Brown fat thermogenesis and body weight regulation in mice: relevance to humans. Int J Obes (Lond) 34Suppl 1: S23-27.
-
(2010)
Int J Obes (Lond)
, vol.34
-
-
Kozak, L.P.1
Koza, R.A.2
Anunciado-Koza, R.3
-
38
-
-
84869497609
-
FNDC5 and irisin in humans: I. Predictors of circulating concentrations in serum and plasma and II. mRNA expression and circulating concentrations in response to weight loss and exercise
-
Huh JY, Panagiotou G, Mougios V, Brinkoetter M, Vamvini MT, et al. (2012) FNDC5 and irisin in humans: I. Predictors of circulating concentrations in serum and plasma and II. mRNA expression and circulating concentrations in response to weight loss and exercise. Metabolism 61 (12): 1725-1738.
-
(2012)
Metabolism
, vol.61
, Issue.12
, pp. 1725-1738
-
-
Huh, J.Y.1
Panagiotou, G.2
Mougios, V.3
Brinkoetter, M.4
Vamvini, M.T.5
-
39
-
-
20144368638
-
Integrated genomic and proteomic analyses of gene expression in Mammalian cells
-
Tian Q, Stepaniants SB, Mao M, Weng L, Feetham MC, et al. (2004) Integrated genomic and proteomic analyses of gene expression in Mammalian cells. Mol Cell Proteomics 3: 960-969.
-
(2004)
Mol Cell Proteomics
, vol.3
, pp. 960-969
-
-
Tian, Q.1
Stepaniants, S.B.2
Mao, M.3
Weng, L.4
Feetham, M.C.5
-
40
-
-
13844299232
-
Integrating gene and protein expression data: pattern analysis and profile mining
-
Cox B, Kislinger T, Emili A, (2005) Integrating gene and protein expression data: pattern analysis and profile mining. Methods 35: 303-314.
-
(2005)
Methods
, vol.35
, pp. 303-314
-
-
Cox, B.1
Kislinger, T.2
Emili, A.3
-
41
-
-
84871587312
-
Circulating levels of irisin in patients with anorexia nervosa and different stages of obesity - Correlation with body mass index
-
Stengel A, Hofmann T, Goebel-Stengel M, Elbelt U, Kobelt P, et al. (2012) Circulating levels of irisin in patients with anorexia nervosa and different stages of obesity - Correlation with body mass index. Peptides 39C: 125-130.
-
(2012)
Peptides
, vol.39 C
, pp. 125-130
-
-
Stengel, A.1
Hofmann, T.2
Goebel-Stengel, M.3
Elbelt, U.4
Kobelt, P.5
|