-
2
-
-
77953169046
-
Cellular bioenergetics as a target for obesity therapy
-
Tseng, Y. H., Cypess, A. M. and Kahn, C. R. (2010) Cellular bioenergetics as a target for obesity therapy. Nat. Rev. Drug Discovery 9, 465-482
-
(2010)
Nat. Rev. Drug Discovery
, vol.9
, pp. 465-482
-
-
Tseng, Y.H.1
Cypess, A.M.2
Kahn, C.R.3
-
3
-
-
35348874911
-
Developmental Origin of Fat: Tracking Obesity to Its Source
-
DOI 10.1016/j.cell.2007.10.004, PII S009286740701272X
-
Gesta, S., Tseng, Y. H. and Kahn, C. R. (2007) Developmental origin of fat: tracking obesity to its source. Cell 131, 242-256 (Pubitemid 47576146)
-
(2007)
Cell
, vol.131
, Issue.2
, pp. 242-256
-
-
Gesta, S.1
Tseng, Y.-H.2
Kahn, C.R.3
-
4
-
-
84861037753
-
The holy grail of metabolic disease: Brown adipose tissue
-
Bartelt, A. and Heeren, J. (2012) The holy grail of metabolic disease: brown adipose tissue. Curr. Opin. Lipidol. 23, 190-195
-
(2012)
Curr. Opin. Lipidol.
, vol.23
, pp. 190-195
-
-
Bartelt, A.1
Heeren, J.2
-
5
-
-
0036269774
-
The effect of sex, age and race on estimating percentage body fat from body mass index: The Heritage Family Study
-
DOI 10.1038/sj.ijo.0802006
-
Jackson, A. S., Stanforth, P. R., Gagnon, J., Rankinen, T., Leon, A. S., Rao, D. C., Skinner, J. S., Bouchard, C. and Wilmore, J. H. (2002) The effect of sex, age and race on estimating percentage body fat from body mass index: The Heritage Family Study. Int. J. Obes. Relat. Metab. Disord. 26, 789-796 (Pubitemid 34620871)
-
(2002)
International Journal of Obesity
, vol.26
, Issue.6
, pp. 789-796
-
-
Jackson, A.S.1
Stanforth, P.R.2
Gagnon, J.3
Rankinen, T.4
Leon, A.S.5
Rao, D.C.6
Skinner, J.S.7
Bouchard, C.8
Wilmore, J.H.9
-
6
-
-
77953809603
-
Metabolic consequences of the presence or absence of the thermogenic capacity of brown adipose tissue in mice (and probably in humans)
-
Cannon, B. and Nedergaard, J. (2010) Metabolic consequences of the presence or absence of the thermogenic capacity of brown adipose tissue in mice (and probably in humans). Int. J. Obes. 34 (Suppl. 1), S7-S16
-
(2010)
Int. J. Obes.
, vol.34
, Issue.SUPPL. 1
-
-
Cannon, B.1
Nedergaard, J.2
-
7
-
-
58749091645
-
UCP1 ablation induces obesity and abolishes diet-induced thermogenesis in mice exempt from thermal stress by living at thermoneutrality
-
Feldmann, H. M., Golozoubova, V., Cannon, B. and Nedergaard, J. (2009) UCP1 ablation induces obesity and abolishes diet-induced thermogenesis in mice exempt from thermal stress by living at thermoneutrality. Cell Metab. 9, 203-209
-
(2009)
Cell Metab.
, vol.9
, pp. 203-209
-
-
Feldmann, H.M.1
Golozoubova, V.2
Cannon, B.3
Nedergaard, J.4
-
8
-
-
0027731309
-
Development of obesity in transgenic mice after genetic ablation of brown adipose tissue
-
DOI 10.1038/366740a0
-
Lowell, B. B., Susulic, V., Hamann, A., Lawitts, J. A., Himms-Hagen, J., Boyer, B. B., Kozak, L. P. and Flier, J. S. (1993) Development of obesity in transgenic mice after genetic ablation of brown adipose tissue. Nature 366, 740-742 (Pubitemid 24038513)
-
(1993)
Nature
, vol.366
, Issue.6457
, pp. 740-742
-
-
Lowell, B.B.1
S-Susulic, V.2
Hamann, A.3
Lawitts, J.A.4
Himms-Hagen, J.5
Boyer, B.B.6
Kozak, L.P.7
Flier, J.S.8
-
9
-
-
33748942837
-
Transcriptional control of adipocyte formation
-
Farmer, S. R. (2006) Transcriptional control of adipocyte formation. Cell Metab. 4, 263-273
-
(2006)
Cell Metab.
, vol.4
, pp. 263-273
-
-
Farmer, S.R.1
-
10
-
-
44149120984
-
Molecular determinants of brown adipocyte formation and function
-
Farmer, S. R. (2008) Molecular determinants of brown adipocyte formation and function. Genes Dev. 22, 1269-1275
-
(2008)
Genes Dev.
, vol.22
, pp. 1269-1275
-
-
Farmer, S.R.1
-
11
-
-
77950245008
-
Transcriptional control of brown fat development
-
Kajimura, S., Seale, P. and Spiegelman, B. M. (2010) Transcriptional control of brown fat development. Cell Metab. 11, 257-262
-
(2010)
Cell Metab.
, vol.11
, pp. 257-262
-
-
Kajimura, S.1
Seale, P.2
Spiegelman, B.M.3
-
12
-
-
33845325476
-
Adipocyte differentiation from the inside out
-
DOI 10.1038/nrm2066, PII NRM2066
-
Rosen, E. D. and MacDougald, O. A. (2006) Adipocyte differentiation from the inside out. Nat. Rev. Mol. Cell Biol. 7, 885-896 (Pubitemid 44871415)
-
(2006)
Nature Reviews Molecular Cell Biology
, vol.7
, Issue.12
, pp. 885-896
-
-
Rosen, E.D.1
MacDougald, O.A.2
-
13
-
-
64349121056
-
Transcriptional control of brown adipocyte development and physiological function: Of mice and men
-
Seale, P., Kajimura, S. and Spiegelman, B. M. (2009) Transcriptional control of brown adipocyte development and physiological function: of mice and men. Genes Dev. 23, 788-797
-
(2009)
Genes Dev.
, vol.23
, pp. 788-797
-
-
Seale, P.1
Kajimura, S.2
Spiegelman, B.M.3
-
14
-
-
79952115255
-
Brown adipose tissue: A promising target to combat obesity
-
Vernochet, C., McDonald, M. E. and Farmer, S. R. (2010) Brown adipose tissue: a promising target to combat obesity. Drug News Perspect. 23, 409-417
-
(2010)
Drug News Perspect
, vol.23
, pp. 409-417
-
-
Vernochet, C.1
McDonald, M.E.2
Farmer, S.R.3
-
15
-
-
0028641559
-
Stimulation of adipogenesis in fibroblasts by PPAR γ2, a lipid-activated transcription factor
-
Tontonoz, P., Hu, E. and Spiegelman, B. M. (1994) Stimulation of adipogenesis in fibroblasts by PPAR γ2, a lipid-activated transcription factor. Cell 79, 1147-1156
-
(1994)
Cell
, vol.79
, pp. 1147-1156
-
-
Tontonoz, P.1
Hu, E.2
Spiegelman, B.M.3
-
16
-
-
0032727505
-
Transcriptional activation of adipogenesis
-
Wu, Z., Puigserver, P. and Spiegelman, B. M. (1999) Transcriptional activation of adipogenesis. Curr. Opin. Cell Biol. 11, 689-694
-
(1999)
Curr. Opin. Cell Biol.
, vol.11
, pp. 689-694
-
-
Wu, Z.1
Puigserver, P.2
Spiegelman, B.M.3
-
17
-
-
0032549811
-
A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis
-
DOI 10.1016/S0092-8674(00)81410-5
-
Puigserver, P., Wu, Z., Park, C. W., Graves, R., Wright, M. and Spiegelman, B. M. (1998) A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis. Cell 92, 829-839 (Pubitemid 28155321)
-
(1998)
Cell
, vol.92
, Issue.6
, pp. 829-839
-
-
Puigserver, P.1
Wu, Z.2
Park, C.W.3
Graves, R.4
Wright, M.5
Spiegelman, B.M.6
-
18
-
-
69349088117
-
Initiation of myoblast to brown fat switch by a PRDM16-C/EBP-β transcriptional complex
-
Kajimura, S., Seale, P., Kubota, K., Lunsford, E., Frangioni, J. V., Gygi, S. P. and Spiegelman, B. M. (2009) Initiation of myoblast to brown fat switch by a PRDM16-C/EBP-β transcriptional complex. Nature 460, 1154-1158
-
(2009)
Nature
, vol.460
, pp. 1154-1158
-
-
Kajimura, S.1
Seale, P.2
Kubota, K.3
Lunsford, E.4
Frangioni, J.V.5
Gygi, S.P.6
Spiegelman, B.M.7
-
19
-
-
34347326271
-
Transcriptional Control of Brown Fat Determination by PRDM16
-
DOI 10.1016/j.cmet.2007.06.001, PII S155041310700157X
-
Seale, P., Kajimura, S., Yang, W., Chin, S., Rohas, L. M., Uldry, M., Tavernier, G., Langin, D. and Spiegelman, B. M. (2007) Transcriptional control of brown fat determination by PRDM16. Cell Metab. 6, 38-54 (Pubitemid 47008902)
-
(2007)
Cell Metabolism
, vol.6
, Issue.1
, pp. 38-54
-
-
Seale, P.1
Kajimura, S.2
Yang, W.3
Chin, S.4
Rohas, L.M.5
Uldry, M.6
Tavernier, G.7
Langin, D.8
Spiegelman, B.M.9
-
20
-
-
84864615516
-
Brown remodeling of white adipose tissue by SirT1-dependent deacetylation of Pparγ
-
Qiang, L., Wang, L., Kon, N., Zhao, W., Lee, S., Zhang, Y., Rosenbaum, M., Zhao, Y., Gu, W., Farmer, S. R. and Accili, D. (2012) Brown remodeling of white adipose tissue by SirT1-dependent deacetylation of Pparγ. Cell 150, 620-632
-
(2012)
Cell
, vol.150
, pp. 620-632
-
-
Qiang, L.1
Wang, L.2
Kon, N.3
Zhao, W.4
Lee, S.5
Zhang, Y.6
Rosenbaum, M.7
Zhao, Y.8
Gu, W.9
Farmer, S.R.10
Accili, D.11
-
21
-
-
84875900015
-
EBF2 determines and maintains brown adipocyte identity
-
Rajakumari, S., Wu, J., Ishibashi, J., Lim, H. W., Giang, A. H., Won, K. J., Reed, R. R. and Seale, P. (2013) EBF2 determines and maintains brown adipocyte identity. Cell Metab. 17, 562-574
-
(2013)
Cell Metab.
, vol.17
, pp. 562-574
-
-
Rajakumari, S.1
Wu, J.2
Ishibashi, J.3
Lim, H.W.4
Giang, A.H.5
Won, K.J.6
Reed, R.R.7
Seale, P.8
-
22
-
-
64349105205
-
Identification and importance of brown adipose tissue in adult humans
-
Cypess, A. M., Lehman, S., Williams, G., Tal, I., Rodman, D., Goldfine, A. B., Kuo, F. C., Palmer, E. L., Tseng, Y. H., Doria, A. et al. (2009) Identification and importance of brown adipose tissue in adult humans. N. Engl. J. Med. 360, 1509-1517
-
(2009)
N. Engl. J. Med.
, vol.360
, pp. 1509-1517
-
-
Cypess, A.M.1
Lehman, S.2
Williams, G.3
Tal, I.4
Rodman, D.5
Goldfine, A.B.6
Kuo, F.C.7
Palmer, E.L.8
Tseng, Y.H.9
Doria, A.10
-
23
-
-
64349095231
-
Cold-activated brown adipose tissue in healthy men
-
Marken Lichtenbelt, W. D., Vanhommerig, J. W., Smulders, N. M., Drossaerts, J. M., Kemerink, G. J., Bouvy, N. D., Schrauwen, P. and Teule, G. J. (2009) Cold-activated brown adipose tissue in healthy men. N. Engl. J. Med. 360, 1500-1508
-
(2009)
N. Engl. J. Med.
, vol.360
, pp. 1500-1508
-
-
Marken Lichtenbelt, W.D.1
Vanhommerig, J.W.2
Smulders, N.M.3
Drossaerts, J.M.4
Kemerink, G.J.5
Bouvy, N.D.6
Schrauwen, P.7
Teule, G.J.8
-
24
-
-
34547631960
-
Unexpected evidence for active brown adipose tissue in adult humans
-
DOI 10.1152/ajpendo.00691.2006
-
Nedergaard, J., Bengtsson, T. and Cannon, B. (2007) Unexpected evidence for active brown adipose tissue in adult humans. Am. J. Physiol. Endocrinol. Metab. 293, E444-E452 (Pubitemid 47205086)
-
(2007)
American Journal of Physiology - Endocrinology and Metabolism
, vol.293
, Issue.2
-
-
Nedergaard, J.1
Bengtsson, T.2
Cannon, B.3
-
25
-
-
64349123664
-
Functional brown adipose tissue in healthy adults
-
Virtanen, K. A., Lidell, M. E., Orava, J., Heglind, M., Westergren, R., Niemi, T., Taittonen, M., Laine, J., Savisto, N. J., Enerback, S. and Nuutila, P. (2009) Functional brown adipose tissue in healthy adults. N. Engl. J. Med. 360, 1518-1525
-
(2009)
N. Engl. J. Med.
, vol.360
, pp. 1518-1525
-
-
Virtanen, K.A.1
Lidell, M.E.2
Orava, J.3
Heglind, M.4
Westergren, R.5
Niemi, T.6
Taittonen, M.7
Laine, J.8
Savisto, N.J.9
Enerback, S.10
Nuutila, P.11
-
26
-
-
0015332110
-
The distribution of brown adipose tissue in the human
-
Heaton, J. M. (1972) The distribution of brown adipose tissue in the human. J. Anat. 112, 35-39
-
(1972)
J. Anat.
, vol.112
, pp. 35-39
-
-
Heaton, J.M.1
-
27
-
-
0021081298
-
Uncoupling protein in human brown adipose tissue mitochondria. Isolation and detection by specific antiserum
-
DOI 10.1016/0014-5793(83)80826-6
-
Lean, M. E. and James, W. P. (1983) Uncoupling protein in human brown adipose tissue mitochondria. Isolation and detection by specific antiserum. Growth Regul. 163, 235-240 (Pubitemid 14248842)
-
(1983)
FEBS Letters
, vol.163
, Issue.2
, pp. 235-240
-
-
Lean, M.E.J.1
James, W.P.T.2
-
28
-
-
0022482362
-
Brown adipose tissue in patients with phaeochromocytoma
-
Lean, M. E., James, W. P., Jennings, G. and Trayhurn, P. (1986) Brown adipose tissue in patients with phaeochromocytoma. Int. J. Obes. 10, 219-227 (Pubitemid 16048557)
-
(1986)
International Journal of Obesity
, vol.10
, Issue.3
, pp. 219-227
-
-
Lean, M.E.J.1
James, W.P.T.2
Jennings, G.3
Trayhurn, P.4
-
29
-
-
0020466632
-
Ultrastructural and biochemical characterization of human brown adipose tissue in pheochromocytoma
-
Ricquier, D., Nechad, M. and Mory, G. (1982) Ultrastructural and biochemical characterization of human brown adipose tissue in pheochromocytoma. J. Clin. Endocrinol. Metab. 54, 803-807 (Pubitemid 13240843)
-
(1982)
Journal of Clinical Endocrinology and Metabolism
, vol.54
, Issue.4
, pp. 803-807
-
-
Ricquier, D.1
Nechad, M.2
Mory, G.3
-
30
-
-
50049122271
-
PRDM16 controls a brown fat/skeletal muscle switch
-
Seale, P., Bjork, B., Yang, W., Kajimura, S., Chin, S., Kuang, S., Scime, A., Devarakonda, S., Conroe, H. M., Erdjument-Bromage, H. et al. (2008) PRDM16 controls a brown fat/skeletal muscle switch. Nature 454, 961-967
-
(2008)
Nature
, vol.454
, pp. 961-967
-
-
Seale, P.1
Bjork, B.2
Yang, W.3
Kajimura, S.4
Chin, S.5
Kuang, S.6
Scime, A.7
Devarakonda, S.8
Conroe, H.M.9
Erdjument-Bromage, H.10
-
31
-
-
77953010087
-
Medicine. Beige can be slimming
-
Ishibashi, J. and Seale, P. (2010) Medicine. Beige can be slimming. Science 328, 1113-1114
-
(2010)
Science
, vol.328
, pp. 1113-1114
-
-
Ishibashi, J.1
Seale, P.2
-
32
-
-
77950226740
-
Chronic peroxisome proliferator-activated receptor γ (PPARγ) activation of epididymally derived white adipocyte cultures reveals a population of thermogenically competent, UCP1-containing adipocytes molecularly distinct from classic brown adipocytes
-
Petrovic, N., Walden, T. B., Shabalina, I. G., Timmons, J. A., Cannon, B. and Nedergaard, J. (2009) Chronic peroxisome proliferator-activated receptor γ (PPARγ) activation of epididymally derived white adipocyte cultures reveals a population of thermogenically competent, UCP1-containing adipocytes molecularly distinct from classic brown adipocytes. J. Biol. Chem. 285, 7153-7164
-
(2009)
J. Biol. Chem.
, vol.285
, pp. 7153-7164
-
-
Petrovic, N.1
Walden, T.B.2
Shabalina, I.G.3
Timmons, J.A.4
Cannon, B.5
Nedergaard, J.6
-
33
-
-
0032528169
-
Emergence of brown adipocytes in white fat in mice is under genetic control effects on body weight and adiposity
-
Guerra, C., Koza, R. A., Yamashita, H., Walsh, K. and Kozak, L. P. (1998) Emergence of brown adipocytes in white fat in mice is under genetic control. Effects on body weight and adiposity. J. Clin. Invest. 102, 412-420 (Pubitemid 28335201)
-
(1998)
Journal of Clinical Investigation
, vol.102
, Issue.2
, pp. 412-420
-
-
Guerra, C.1
Koza, R.A.2
Yamashita, H.3
Walsh, K.4
Kozak, L.P.5
-
34
-
-
33847768085
-
Ectopic brown adipose tissue in muscle provides a mechanism for differences in risk of metabolic syndrome in mice
-
DOI 10.1073/pnas.0610416104
-
Almind, K., Manieri, M., Sivitz, W. I., Cinti, S. and Kahn, C. R. (2007) Ectopic brown adipose tissue in muscle provides a mechanism for differences in risk of metabolic syndrome in mice. Proc. Natl. Acad. Sci. U.S.A. 104, 2366-2371 (Pubitemid 46391403)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.7
, pp. 2366-2371
-
-
Almind, K.1
Manieri, M.2
Sivitz, W.I.3
Cinti, S.4
Kahn, C.R.5
-
35
-
-
65649111494
-
The origins of brown adipose tissue
-
Enerback, S. (2009) The origins of brown adipose tissue. N. Engl. J. Med. 360, 2021-2023
-
(2009)
N. Engl. J. Med.
, vol.360
, pp. 2021-2023
-
-
Enerback, S.1
-
36
-
-
84879577791
-
-
Reference deleted
-
Reference deleted
-
-
-
-
37
-
-
79951560291
-
Between brown and white: Novel aspects of adipocyte differentiation
-
Cinti, S. (2011) Between brown and white: novel aspects of adipocyte differentiation. Ann. Med. 43, 104-115
-
(2011)
Ann. Med.
, vol.43
, pp. 104-115
-
-
Cinti, S.1
-
38
-
-
84859465056
-
In vivo identification of bipotential adipocyte progenitors recruited by beta3-adrenoceptor activation and high-fat feeding
-
Lee, Y. H., Petkova, A. P., Mottillo, E. P. and Granneman, J. G. (2012) In vivo identification of bipotential adipocyte progenitors recruited by beta3-adrenoceptor activation and high-fat feeding. Cell Metab. 15, 480-491
-
(2012)
Cell Metab.
, vol.15
, pp. 480-491
-
-
Lee, Y.H.1
Petkova, A.P.2
Mottillo, E.P.3
Granneman, J.G.4
-
39
-
-
78651094465
-
Identification of inducible brown adipocyte progenitors residing in skeletal muscle and white fat
-
Schulz, T. J., Huang, T. L., Tran, T. T., Zhang, H., Townsend, K. L., Shadrach, J. L., Cerletti, M., McDougall, L. E., Giorgadze, N., Tchkonia, T. et al. (2011) Identification of inducible brown adipocyte progenitors residing in skeletal muscle and white fat. Proc. Natl. Acad. Sci. U.S.A. 108, 143-148
-
(2011)
Proc. Natl. Acad. Sci. U.S.A.
, vol.108
, pp. 143-148
-
-
Schulz, T.J.1
Huang, T.L.2
Tran, T.T.3
Zhang, H.4
Townsend, K.L.5
Shadrach, J.L.6
Cerletti, M.7
McDougall, L.E.8
Giorgadze, N.9
Tchkonia, T.10
-
40
-
-
84864287504
-
Beige adipocytes are a distinct type of thermogenic fat cell in mouse and human
-
Wu, J., Bostrom, P., Sparks, L. M., Ye, L., Choi, J. H., Giang, A. H., Khandekar, M., Virtanen, K. A., Nuutila, P., Schaart, G. et al. (2012) Beige adipocytes are a distinct type of thermogenic fat cell in mouse and human. Cell 150, 366-376
-
(2012)
Cell
, vol.150
, pp. 366-376
-
-
Wu, J.1
Bostrom, P.2
Sparks, L.M.3
Ye, L.4
Choi, J.H.5
Giang, A.H.6
Khandekar, M.7
Virtanen, K.A.8
Nuutila, P.9
Schaart, G.10
-
41
-
-
0028246730
-
Neural crest cell formation and migration in the developing embryo
-
Bronner-Fraser, M. (1994) Neural crest cell formation and migration in the developing embryo. FASEB J. 8, 699-706
-
(1994)
FASEB J.
, vol.8
, pp. 699-706
-
-
Bronner-Fraser, M.1
-
42
-
-
53349160483
-
Developmental origin of adipocytes: New insights into a pending question
-
Billon, N., Monteiro, M. C. and Dani, C. (2008) Developmental origin of adipocytes: new insights into a pending question. Biol. Cell 100, 563-575
-
(2008)
Biol. Cell
, vol.100
, pp. 563-575
-
-
Billon, N.1
Monteiro, M.C.2
Dani, C.3
-
44
-
-
0025939597
-
Expression of p53 during mouse embryogenesis
-
Schmid, P., Lorenz, A., Hameister, H. and Montenarh, M. (1991) Expression of p53 during mouse embryogenesis. Development 113, 857-865 (Pubitemid 21900325)
-
(1991)
Development
, vol.113
, Issue.3
, pp. 857-865
-
-
Schmid, P.1
Lorenz, A.2
Hameister, H.3
Montenarh, M.4
-
45
-
-
84875367849
-
Brown-fat paucity due to impaired BMP signalling induces compensatory browning of white fat
-
Schulz, T. J., Huang, P., Huang, T. L., Xue, R., McDougall, L. E., Townsend, K. L., Cypess, A. M., Mishina, Y., Gussoni, E. and Tseng, Y. H. (2013) Brown-fat paucity due to impaired BMP signalling induces compensatory browning of white fat. Nature 495, 379-383
-
(2013)
Nature
, vol.495
, pp. 379-383
-
-
Schulz, T.J.1
Huang, P.2
Huang, T.L.3
Xue, R.4
McDougall, L.E.5
Townsend, K.L.6
Cypess, A.M.7
Mishina, Y.8
Gussoni, E.9
Tseng, Y.H.10
-
46
-
-
53549130485
-
White fat progenitor cells reside in the adipose vasculature
-
Tang, W., Zeve, D., Suh, J., Bosnakovski, D., Kyba, M., Hammer, B., Tallquist, M. D. and Graff, J. M. (2008) White fat progenitor cells reside in the adipose vasculature. Science 322, 583-586
-
(2008)
Science
, vol.322
, pp. 583-586
-
-
Tang, W.1
Zeve, D.2
Suh, J.3
Bosnakovski, D.4
Kyba, M.5
Hammer, B.6
Tallquist, M.D.7
Graff, J.M.8
-
47
-
-
84856954303
-
The vascular endothelium of the adipose tissue gives rise to both white and brown fat cells
-
Tran, K. V., Gealekman, O., Frontini, A., Zingaretti, M. C., Morroni, M., Giordano, A., Smorlesi, A., Perugini, J., De Matteis, R., Sbarbati, A. et al. (2012) The vascular endothelium of the adipose tissue gives rise to both white and brown fat cells. Cell Metab. 15, 222-229
-
(2012)
Cell Metab.
, vol.15
, pp. 222-229
-
-
Tran, K.V.1
Gealekman, O.2
Frontini, A.3
Zingaretti, M.C.4
Morroni, M.5
Giordano, A.6
Smorlesi, A.7
Perugini, J.8
De Matteis, R.9
Sbarbati, A.10
-
48
-
-
75949096894
-
Muscle injury activates resident fibro/adipogenic progenitors that facilitate myogenesis
-
Joe, A. W., Yi, L., Natarajan, A., Le Grand, F., So, L., Wang, J., Rudnicki, M. A. and Rossi, F. M. (2010) Muscle injury activates resident fibro/adipogenic progenitors that facilitate myogenesis. Nat. Cell Biol. 12, 153-163
-
(2010)
Nat. Cell Biol.
, vol.12
, pp. 153-163
-
-
Joe, A.W.1
Yi, L.2
Natarajan, A.3
Le Grand, F.4
So, L.5
Wang, J.6
Rudnicki, M.A.7
Rossi, F.M.8
-
49
-
-
53549134683
-
Identification of white adipocyte progenitor cells in vivo
-
Rodeheffer, M. S., Birsoy, K. and Friedman, J. M. (2008) Identification of white adipocyte progenitor cells in vivo. Cell 135, 240-249
-
(2008)
Cell
, vol.135
, pp. 240-249
-
-
Rodeheffer, M.S.1
Birsoy, K.2
Friedman, J.M.3
-
50
-
-
75949130333
-
Mesenchymal progenitors distinct from satellite cells contribute to ectopic fat cell formation in skeletal muscle
-
Uezumi, A., Fukada, S., Yamamoto, N., Takeda, S. and Tsuchida, K. (2010) Mesenchymal progenitors distinct from satellite cells contribute to ectopic fat cell formation in skeletal muscle. Nat. Cell Biol. 12, 143-152
-
(2010)
Nat. Cell Biol.
, vol.12
, pp. 143-152
-
-
Uezumi, A.1
Fukada, S.2
Yamamoto, N.3
Takeda, S.4
Tsuchida, K.5
-
51
-
-
84874657953
-
Characterization of the adipocyte cellular lineage in vivo
-
Berry, R. and Rodeheffer, M. S. (2013) Characterization of the adipocyte cellular lineage in vivo. Nat. Cell Biol. 15, 302-308
-
(2013)
Nat. Cell Biol.
, vol.15
, pp. 302-308
-
-
Berry, R.1
Rodeheffer, M.S.2
-
52
-
-
77950081353
-
Transcriptional control of preadipocyte determination by Zfp423
-
Gupta, R. K., Arany, Z., Seale, P., Mepani, R. J., Ye, L., Conroe, H. M., Roby, Y. A., Kulaga, H., Reed, R. R. and Spiegelman, B. M. (2010) Transcriptional control of preadipocyte determination by Zfp423. Nature 464, 619-623
-
(2010)
Nature
, vol.464
, pp. 619-623
-
-
Gupta, R.K.1
Arany, Z.2
Seale, P.3
Mepani, R.J.4
Ye, L.5
Conroe, H.M.6
Roby, Y.A.7
Kulaga, H.8
Reed, R.R.9
Spiegelman, B.M.10
-
53
-
-
84856970831
-
Zfp423 expression identifies committed preadipocytes and localizes to adipose endothelial and perivascular cells
-
Gupta, R. K., Mepani, R. J., Kleiner, S., Lo, J. C., Khandekar, M. J., Cohen, P., Frontini, A., Bhowmick, D. C., Ye, L., Cinti, S. and Spiegelman, B. M. (2012) Zfp423 expression identifies committed preadipocytes and localizes to adipose endothelial and perivascular cells. Cell Metab. 15, 230-239
-
(2012)
Cell Metab.
, vol.15
, pp. 230-239
-
-
Gupta, R.K.1
Mepani, R.J.2
Kleiner, S.3
Lo, J.C.4
Khandekar, M.J.5
Cohen, P.6
Frontini, A.7
Bhowmick, D.C.8
Ye, L.9
Cinti, S.10
Spiegelman, B.M.11
-
54
-
-
84870279173
-
Regulation of early adipose commitment by Zfp521
-
Kang, S., Akerblad, P., Kiviranta, R., Gupta, R. K., Kajimura, S., Griffin, M. J., Min, J., Baron, R. and Rosen, E. D. (2012) Regulation of early adipose commitment by Zfp521. PLoS Biol. 10, e1001433
-
(2012)
PLoS Biol.
, vol.10
-
-
Kang, S.1
Akerblad, P.2
Kiviranta, R.3
Gupta, R.K.4
Kajimura, S.5
Griffin, M.J.6
Min, J.7
Baron, R.8
Rosen, E.D.9
-
55
-
-
33846152299
-
Critical role for Ebf1 and Ebf2 in the adipogenic transcriptional cascade
-
DOI 10.1128/MCB.01557-06
-
Jimenez, M. A., Akerblad, P., Sigvardsson, M. and Rosen, E. D. (2007) Critical role for Ebf1 and Ebf2 in the adipogenic transcriptional cascade. Mol. Cell. Biol. 27, 743-757 (Pubitemid 46080139)
-
(2007)
Molecular and Cellular Biology
, vol.27
, Issue.2
, pp. 743-757
-
-
Jimenez, M.A.1
Akerblad, P.2
Sigvardsson, M.3
Rosen, E.D.4
-
56
-
-
50049097319
-
Developmental biology: Neither fat nor flesh
-
Cannon, B. and Nedergaard, J. (2008) Developmental biology: neither fat nor flesh. Nature 454, 947-948
-
(2008)
Nature
, vol.454
, pp. 947-948
-
-
Cannon, B.1
Nedergaard, J.2
-
57
-
-
77954741222
-
Inducible lineage tracing of Pax7-descendant cells reveals embryonic origin of adult satellite cells
-
Lepper, C. and Fan, C. M. (2010) Inducible lineage tracing of Pax7-descendant cells reveals embryonic origin of adult satellite cells. Genesis 48, 424-436
-
(2010)
Genesis
, vol.48
, pp. 424-436
-
-
Lepper, C.1
Fan, C.M.2
-
58
-
-
34248372084
-
Myogenic gene expression signature establishes that brown and white adipocytes originate from distinct cell lineages
-
DOI 10.1073/pnas.0610615104
-
Timmons, J. A., Wennmalm, K., Larsson, O., Walden, T. B., Lassmann, T., Petrovic, N., Hamilton, D. L., Gimeno, R. E., Wahlestedt, C., Baar, K. et al. (2007) Myogenic gene expression signature establishes that brown and white adipocytes originate from distinct cell lineages. Proc. Natl. Acad. Sci. U.S.A. 104, 4401-4406 (Pubitemid 47186238)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.11
, pp. 4401-4406
-
-
Timmons, J.A.1
Wennmalm, K.2
Larsson, O.3
Walden, T.B.4
Lassmann, T.5
Petrovic, N.6
Hamilton, D.L.7
Gimeno, R.E.8
Wahlestedt, C.9
Baar, K.10
Nedergaard, J.11
Cannon, B.12
-
59
-
-
0027258162
-
Muscle deficiency and neonatal death in mice with a targeted mutation in the myogenin gene
-
DOI 10.1038/364501a0
-
Hasty, P., Bradley, A., Morris, J. H., Edmondson, D. G., Venuti, J. M., Olson, E. N. and Klein, W. H. (1993) Muscle deficiency and neonatal death in mice with a targeted mutation in the myogenin gene. Nature 364, 501-506 (Pubitemid 23273093)
-
(1993)
Nature
, vol.364
, Issue.6437
, pp. 501-506
-
-
Hasty, P.1
Bradley, A.2
Morris, J.H.3
Edmondson, D.G.4
Venuti, J.M.5
Olson, E.N.6
Klein, W.H.7
-
60
-
-
0038206882
-
Myf5 and MyoD activation define independent myogenic compartments during embryonic development
-
DOI 10.1016/S0012-1606(03)00139-8
-
Kablar, B., Krastel, K., Tajbakhsh, S. and Rudnicki, M. A. (2003) Myf5 and MyoD activation define independent myogenic compartments during embryonic development. Dev. Biol. 258, 307-318 (Pubitemid 36683133)
-
(2003)
Developmental Biology
, vol.258
, Issue.2
, pp. 307-318
-
-
Kablar, B.1
Krastel, K.2
Tajbakhsh, S.3
Rudnicki, M.A.4
-
61
-
-
84865792944
-
PTEN loss in the Myf5 lineage redistributes body fat and reveals subsets of white adipocytes that arise from Myf5 precursors
-
Sanchez-Gurmaches, J., Hung, C. M., Sparks, C. A., Tang, Y., Li, H. and Guertin, D. A. (2012) PTEN loss in the Myf5 lineage redistributes body fat and reveals subsets of white adipocytes that arise from Myf5 precursors. Cell Metab. 16, 348-362
-
(2012)
Cell Metab.
, vol.16
, pp. 348-362
-
-
Sanchez-Gurmaches, J.1
Hung, C.M.2
Sparks, C.A.3
Tang, Y.4
Li, H.5
Guertin, D.A.6
-
62
-
-
0035366502
-
Emergence during development of the white-adipocyte cell phenotype is independent of the brown-adipocyte cell phenotype
-
DOI 10.1042/0264-6021:3560659
-
Moulin, K., Truel, N., Andre, M., Arnauld, E., Nibbelink, M., Cousin, B., Dani, C., Penicaud, L. and Casteilla, L. (2001) Emergence during development of the white-adipocyte cell phenotype is independent of the brown-adipocyte cell phenotype. Biochem. J. 356, 659-664 (Pubitemid 32532380)
-
(2001)
Biochemical Journal
, vol.356
, Issue.2
, pp. 659-664
-
-
Moulin, K.1
Truel, N.2
Andre, M.3
Arnauld, E.4
Nibbelink, M.5
Cousin, B.6
Dani, C.7
Penicaud8
Casteilla, L.9
-
63
-
-
46149102685
-
Highly Efficient, Functional Engraftment of Skeletal Muscle Stem Cells in Dystrophic Muscles
-
DOI 10.1016/j.cell.2008.05.049, PII S0092867408007551
-
Cerletti, M., Jurga, S., Witczak, C. A., Hirshman, M. F., Shadrach, J. L., Goodyear, L. J. and Wagers, A. J. (2008) Highly efficient, functional engraftment of skeletal muscle stem cells in dystrophic muscles. Cell 134, 37-47 (Pubitemid 351905744)
-
(2008)
Cell
, vol.134
, Issue.1
, pp. 37-47
-
-
Cerletti, M.1
Jurga, S.2
Witczak, C.A.3
Hirshman, M.F.4
Shadrach, J.L.5
Goodyear, L.J.6
Wagers, A.J.7
-
64
-
-
54049143270
-
Reversible transdifferentiation in the adipose organ
-
Cinti, S. (2008) Reversible transdifferentiation in the adipose organ. Int. J. Pediatr. Obes. 3 (Suppl. 2), 21-26
-
(2008)
Int. J. Pediatr. Obes.
, vol.3
, Issue.SUPPL. 2
, pp. 21-26
-
-
Cinti, S.1
-
65
-
-
77949327079
-
Reversible physiological transdifferentiation in the adipose organ
-
Cinti, S. (2009) Reversible physiological transdifferentiation in the adipose organ. Proc. Nutr. Soc. 68, 340-349
-
(2009)
Proc. Nutr. Soc.
, vol.68
, pp. 340-349
-
-
Cinti, S.1
-
66
-
-
70350443275
-
Transdifferentiation properties of adipocytes in the adipose organ
-
Cinti, S. (2009) Transdifferentiation properties of adipocytes in the adipose organ. Am. J. Physiol. Endocrinol. Metab. 297, E977-E986
-
(2009)
Am. J. Physiol. Endocrinol. Metab.
, vol.297
-
-
Cinti, S.1
-
67
-
-
70649109834
-
Emerging role of bone morphogenetic proteins in adipogenesis and energy metabolism
-
Schulz, T. J. and Tseng, Y. H. (2009) Emerging role of bone morphogenetic proteins in adipogenesis and energy metabolism. Cytokine Growth Factor Rev. 20, 523-531
-
(2009)
Cytokine Growth Factor Rev.
, vol.20
, pp. 523-531
-
-
Schulz, T.J.1
Tseng, Y.H.2
-
68
-
-
33745966038
-
β-Catenin activation is necessary and sufficient to specify the dorsal dermal fate in the mouse
-
Atit, R., Sgaier, S. K., Mohamed, O. A., Taketo, M. M., Dufort, D., Joyner, A. L., Niswander, L. and Conlon, R. A. (2006) β-Catenin activation is necessary and sufficient to specify the dorsal dermal fate in the mouse. Dev. Biol. 296, 164-176
-
(2006)
Dev. Biol.
, vol.296
, pp. 164-176
-
-
Atit, R.1
Sgaier, S.K.2
Mohamed, O.A.3
Taketo, M.M.4
Dufort, D.5
Joyner, A.L.6
Niswander, L.7
Conlon, R.A.8
-
69
-
-
0034697007
-
Fibroblast growth factor-16 is a growth factor for embryonic brown adipocytes
-
DOI 10.1074/jbc.275.16.12119
-
Konishi, M., Mikami, T., Yamasaki, M., Miyake, A. and Itoh, N. (2000) Fibroblast growth factor-16 is a growth factor for embryonic brown adipocytes. J. Biol. Chem. 275, 12119-12122 (Pubitemid 30237788)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.16
, pp. 12119-12122
-
-
Konishi, M.1
Mikami, T.2
Yamasaki, M.3
Miyake, A.4
Itoh, N.5
-
70
-
-
4143115909
-
Wnt10b inhibits development of white and brown adipose tissues
-
DOI 10.1074/jbc.M402937200
-
Longo, K. A., Wright, W. S., Kang, S., Gerin, I., Chiang, S. H., Lucas, P. C., Opp, M. R. and MacDougald, O. A. (2004) Wnt10b inhibits development of white and brown adipose tissues. J. Biol. Chem. 279, 35503-35509 (Pubitemid 39100550)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.34
, pp. 35503-35509
-
-
Longo, K.A.1
Wright, W.S.2
Kang, S.3
Gerin, I.4
Chiang, S.-H.5
Lucas, P.C.6
Opp, M.R.7
MacDougald, O.A.8
-
71
-
-
73349130440
-
Drosophila genome-wide obesity screen reveals hedgehog as a determinant of brown versus white adipose cell fate
-
Pospisilik, J. A., Schramek, D., Schnidar, H., Cronin, S. J., Nehme, N. T., Zhang, X., Knauf, C., Cani, P. D., Aumayr, K., Todoric, J. et al. (2010) Drosophila genome-wide obesity screen reveals hedgehog as a determinant of brown versus white adipose cell fate. Cell 140, 148-160
-
(2010)
Cell
, vol.140
, pp. 148-160
-
-
Pospisilik, J.A.1
Schramek, D.2
Schnidar, H.3
Cronin, S.J.4
Nehme, N.T.5
Zhang, X.6
Knauf, C.7
Cani, P.D.8
Aumayr, K.9
Todoric, J.10
-
72
-
-
18344394556
-
Transgenic mice expressing human fibroblast growth factor-19 display increased metabolic rate and decreased adiposity
-
DOI 10.1210/en.143.5.1741
-
Tomlinson, E., Fu, L., John, L., Hultgren, B., Huang, X., Renz, M., Stephan, J. P., Tsai, S. P., Powell-Braxton, L., French, D. and Stewart, T. A. (2002) Transgenic mice expressing human fibroblast growth factor-19 display increased metabolic rate and decreased adiposity. Endocrinology 143, 1741-1747 (Pubitemid 34415889)
-
(2002)
Endocrinology
, vol.143
, Issue.5
, pp. 1741-1747
-
-
Tomlinson, E.1
Fu, L.2
John, L.3
Hultgren, B.4
Huang, X.5
Renz, M.6
Stephan, J.P.7
Tsai, S.P.8
Powell-Braxton, L.9
French, D.10
Stewart, T.A.11
-
73
-
-
50049127055
-
New role of bone morphogenetic protein 7 in brown adipogenesis and energy expenditure
-
Tseng, Y. H., Kokkotou, E., Schulz, T. J., Huang, T. L., Winnay, J. N., Taniguchi, C. M., Tran, T. T., Suzuki, R., Espinoza, D. O., Yamamoto, Y. et al. (2008) New role of bone morphogenetic protein 7 in brown adipogenesis and energy expenditure. Nature 454, 1000-1004
-
(2008)
Nature
, vol.454
, pp. 1000-1004
-
-
Tseng, Y.H.1
Kokkotou, E.2
Schulz, T.J.3
Huang, T.L.4
Winnay, J.N.5
Taniguchi, C.M.6
Tran, T.T.7
Suzuki, R.8
Espinoza, D.O.9
Yamamoto, Y.10
-
74
-
-
16344373011
-
Wnt10b deficiency promotes coexpression of myogenic and adipogenic programs in myoblasts
-
DOI 10.1091/mbc.E04-08-0720
-
Vertino, A. M., Taylor-Jones, J. M., Longo, K. A., Bearden, E. D., Lane, T. F., McGehee, Jr, R. E., MacDougald, O. A. and Peterson, C. A. (2005) Wnt10b deficiency promotes coexpression of myogenic and adipogenic programs in myoblasts. Mol. Biol. Cell 16, 2039-2048 (Pubitemid 40471969)
-
(2005)
Molecular Biology of the Cell
, vol.16
, Issue.4
, pp. 2039-2048
-
-
Vertino, A.M.1
Taylor-Jones, J.M.2
Longo, K.A.3
Bearden, E.D.4
Lane, T.F.5
McGehee Jr., R.E.6
MacDougald, O.A.7
Peterson, C.A.8
-
75
-
-
3042759742
-
Commitment of C3H10T1/2 pluripotent stem cells to the adipocyte lineage
-
DOI 10.1073/pnas.0403100101
-
Tang, Q. Q., Otto, T. C. and Lane, M. D. (2004) Commitment of C3H10T1/2 pluripotent stem cells to the adipocyte lineage. Proc. Natl. Acad. Sci. U.S.A. 101, 9607-9611 (Pubitemid 38869283)
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, Issue.26
, pp. 9607-9611
-
-
Tang, Q.-Q.1
Otto, T.C.2
Lane, M.D.3
-
76
-
-
34250019537
-
Bone: Formation by autoinduction
-
Urist, M. R. (1965) Bone: formation by autoinduction. Science 150, 893-899
-
(1965)
Science
, vol.150
, pp. 893-899
-
-
Urist, M.R.1
-
77
-
-
0031093601
-
Bone morphogenetic protein: The molecularization of skeletal system development
-
Urist, M. R. (1997) Bone morphogenetic protein: the molecularization of skeletal system development. J. Bone Miner. Res. 12, 343-346
-
(1997)
J. Bone Miner. Res.
, vol.12
, pp. 343-346
-
-
Urist, M.R.1
-
78
-
-
21344433063
-
BMP signaling and early embryonic patterning
-
DOI 10.1016/j.cytogfr.2005.04.002, PII S1359610105000444
-
Kishigami, S. and Mishina, Y. (2005) BMP signaling and early embryonic patterning. Cytokine Growth Factor Rev. 16, 265-278 (Pubitemid 40910316)
-
(2005)
Cytokine and Growth Factor Reviews
, vol.16
, Issue.3 SPEC. ISS.
, pp. 265-278
-
-
Kishigami, S.1
Mishina, Y.2
-
80
-
-
33846146325
-
BMP-4 treatment of C3H10T1/2 stem cells blocks expression of MMP-3 and MMP-13
-
DOI 10.1016/j.bbrc.2006.12.170, PII S0006291X06028452
-
Otto, T. C., Bowers, R. R. and Lane, M. D. (2006) BMP-4 treatment of C3H10T1/2 stem cells blocks expression of MMP-3 and MMP-13. Biochem. Biophys. Res. Commun. 353, 1097-1104 (Pubitemid 46080411)
-
(2007)
Biochemical and Biophysical Research Communications
, vol.353
, Issue.4
, pp. 1097-1104
-
-
Otto, T.C.1
Bowers, R.R.2
Lane, M.D.3
-
81
-
-
0027185702
-
Bone morphogenetic protein-2 causes commitment and differentiation in C3H10T1/2 and 3T3 cells
-
Wang, E. A., Israel, D. I., Kelly, S. and Luxenberg, D. P. (1993) Bone morphogenetic protein-2 causes commitment and differentiation in C3H10T1/2 and 3T3 cells. Growth Factors 9, 57-71 (Pubitemid 23241842)
-
(1993)
Growth Factors
, vol.9
, Issue.1
, pp. 57-71
-
-
Wang, E.A.1
Israel, D.I.2
Kelly, S.3
Luxenberg, D.P.4
-
82
-
-
84874450879
-
BMP4-mediated brown fat-like changes in white adipose tissue alter glucose and energy homeostasis
-
Qian, S. W., Tang, Y., Li, X., Liu, Y., Zhang, Y. Y., Huang, H. Y., Xue, R. D., Yu, H. Y., Guo, L., Gao, H. D. et al. (2013) BMP4-mediated brown fat-like changes in white adipose tissue alter glucose and energy homeostasis. Proc. Natl. Acad. Sci. U.S.A. 110, E798-E807
-
(2013)
Proc. Natl. Acad. Sci. U.S.A.
, vol.110
-
-
Qian, S.W.1
Tang, Y.2
Li, X.3
Liu, Y.4
Zhang, Y.Y.5
Huang, H.Y.6
Xue, R.D.7
Yu, H.Y.8
Guo, L.9
Gao, H.D.10
-
83
-
-
0028832707
-
A requirement for bone morphogenetic protein-7 during development of the mammalian kidney and eye
-
Dudley, A. T., Lyons, K. M. and Robertson, E. J. (1995) A requirement for bone morphogenetic protein-7 during development of the mammalian kidney and eye. Genes Dev. 9, 2795-2807
-
(1995)
Genes Dev.
, vol.9
, pp. 2795-2807
-
-
Dudley, A.T.1
Lyons, K.M.2
Robertson, E.J.3
-
84
-
-
79959933148
-
Protection from obesity and diabetes by blockade of TGF-β/Smad3 signaling
-
Yadav, H., Quijano, C., Kamaraju, A. K., Gavrilova, O., Malek, R., Chen, W., Zerfas, P., Zhigang, D., Wright, E. C., Stuelten, C. et al. (2011) Protection from obesity and diabetes by blockade of TGF-β/Smad3 signaling. Cell Metab. 14, 67-79
-
(2011)
Cell Metab.
, vol.14
, pp. 67-79
-
-
Yadav, H.1
Quijano, C.2
Kamaraju, A.K.3
Gavrilova, O.4
Malek, R.5
Chen, W.6
Zerfas, P.7
Zhigang, D.8
Wright, E.C.9
Stuelten, C.10
-
85
-
-
79958047295
-
Desnutrin/ATGL is regulated by AMPK and is required for a brown adipose phenotype
-
Ahmadian, M., Abbott, M. J., Tang, T., Hudak, C. S., Kim, Y., Bruss, M., Hellerstein, M. K., Lee, H. Y., Samuel, V. T., Shulman, G. I. et al. (2011) Desnutrin/ATGL is regulated by AMPK and is required for a brown adipose phenotype. Cell Metab. 13, 739-748
-
(2011)
Cell Metab.
, vol.13
, pp. 739-748
-
-
Ahmadian, M.1
Abbott, M.J.2
Tang, T.3
Hudak, C.S.4
Kim, Y.5
Bruss, M.6
Hellerstein, M.K.7
Lee, H.Y.8
Samuel, V.T.9
Shulman, G.I.10
-
86
-
-
2542505481
-
Fibroblast growth factor 19 increases metabolic rate and reverses dietary and leptin-deficient diabetes
-
DOI 10.1210/en.2003-1671
-
Fu, L., John, L. M., Adams, S. H., Yu, X. X., Tomlinson, E., Renz, M., Williams, P. M., Soriano, R., Corpuz, R., Moffat, B. et al. (2004) Fibroblast growth factor 19 increases metabolic rate and reverses dietary and leptin-deficient diabetes. Endocrinology 145, 2594-2603 (Pubitemid 38686202)
-
(2004)
Endocrinology
, vol.145
, Issue.6
, pp. 2594-2603
-
-
Fu, L.1
John, L.M.2
Adams, S.H.3
Yu, X.X.4
Tomlinson, E.5
Renz, M.6
Williams, P.M.7
Soriano, R.8
Corpuz, R.9
Moffat, B.10
Vandlen, R.11
Simmons, L.12
Foster, J.13
Stephan, J.-P.14
Tsai, S.P.15
Stewart, T.A.16
-
87
-
-
84867536639
-
Hedgehog partial agonism drives Warburg-like metabolism in muscle and brown fat
-
Teperino, R., Amann, S., Bayer, M., McGee, S. L., Loipetzberger, A., Connor, T., Jaeger, C., Kammerer, B., Winter, L., Wiche, G. et al. (2012) Hedgehog partial agonism drives Warburg-like metabolism in muscle and brown fat. Cell 151, 414-426
-
(2012)
Cell
, vol.151
, pp. 414-426
-
-
Teperino, R.1
Amann, S.2
Bayer, M.3
McGee, S.L.4
Loipetzberger, A.5
Connor, T.6
Jaeger, C.7
Kammerer, B.8
Winter, L.9
Wiche, G.10
-
88
-
-
65349151258
-
Have we entered the brown adipose tissue renaissance?
-
Ravussin, E. and Kozak, L. P. (2009) Have we entered the brown adipose tissue renaissance? Obes. Rev. 10, 265-268
-
(2009)
Obes. Rev.
, vol.10
, pp. 265-268
-
-
Ravussin, E.1
Kozak, L.P.2
-
89
-
-
4544357340
-
Learning new tricks from old dogs: β-adrenergic receptors teach new lessons on firing up adipose tissue metabolism
-
DOI 10.1210/me.2004-0193
-
Collins, S., Cao, W. and Robidoux, J. (2004) Learning new tricks from old dogs: β-adrenergic receptors teach new lessons on firing up adipose tissue metabolism. Mol. Endocrinol. 18, 2123-2131 (Pubitemid 39215245)
-
(2004)
Molecular Endocrinology
, vol.18
, Issue.9
, pp. 2123-2131
-
-
Collins, S.1
Cao, W.2
Robidoux, J.3
-
90
-
-
78449266620
-
Positive and negative control of Ucp1 gene transcription and the role of β-adrenergic signaling networks
-
Collins, S., Yehuda-Shnaidman, E. and Wang, H. (2010) Positive and negative control of Ucp1 gene transcription and the role of β-adrenergic signaling networks. Int. J. Obes. 34 (Suppl. 1), S28-S33
-
(2010)
Int. J. Obes.
, vol.34
, Issue.SUPPL. 1
-
-
Collins, S.1
Yehuda-Shnaidman, E.2
Wang, H.3
-
91
-
-
84874413612
-
β-Adrenoceptor signaling networks in adipocytes for recruiting stored fat and energy expenditure
-
Collins, S. (2012) β-Adrenoceptor signaling networks in adipocytes for recruiting stored fat and energy expenditure. Front. Endocrinol. 2, 102
-
(2012)
Front. Endocrinol.
, vol.2
, pp. 102
-
-
Collins, S.1
-
92
-
-
79955032433
-
Brown fat biology and thermogenesis
-
Richard, D. and Picard, F. (2011) Brown fat biology and thermogenesis. Front. Biosci. 16, 1233-1260
-
(2011)
Front. Biosci.
, vol.16
, pp. 1233-1260
-
-
Richard, D.1
Picard, F.2
-
93
-
-
84871252686
-
Brown adipose tissue: Recent insights into development, metabolic function, and therapeutic potential
-
Townsend, K. L. and Tseng, Y. H. (2012) Brown adipose tissue: recent insights into development, metabolic function, and therapeutic potential. Adipocyte 1, 13-24
-
(2012)
Adipocyte
, vol.1
, pp. 13-24
-
-
Townsend, K.L.1
Tseng, Y.H.2
-
95
-
-
33751172559
-
The role of brown adipose tissue in human obesity
-
Cinti, S. (2006) The role of brown adipose tissue in human obesity. Nutr. Metab. Cardiovasc. Dis. 16, 569-574
-
(2006)
Nutr. Metab. Cardiovasc. Dis.
, vol.16
, pp. 569-574
-
-
Cinti, S.1
-
96
-
-
77950190436
-
Distribution and development of brown adipocytes in the murine and human adipose organ
-
Frontini, A. and Cinti, S. (2010) Distribution and development of brown adipocytes in the murine and human adipose organ. Cell Metab. 11, 253-256
-
(2010)
Cell Metab.
, vol.11
, pp. 253-256
-
-
Frontini, A.1
Cinti, S.2
-
97
-
-
0033825933
-
Multilocular fat cells in WAT of CL-316243-treated rats derive directly from white adipocytes
-
Himms-Hagen, J., Melnyk, A., Zingaretti, M. C., Ceresi, E., Barbatelli, G. and Cinti, S. (2000) Multilocular fat cells in WAT of CL-316243-treated rats derive directly from white adipocytes. Am. J. Physiol. Cell Physiol. 279, C670-C681
-
(2000)
Am. J. Physiol. Cell Physiol.
, vol.279
-
-
Himms-Hagen, J.1
Melnyk, A.2
Zingaretti, M.C.3
Ceresi, E.4
Barbatelli, G.5
Cinti, S.6
-
98
-
-
34548451564
-
Brain-derived neurotrophic factor in the hypothalamic paraventricular nucleus increases energy expenditure by elevating metabolic rate
-
DOI 10.1152/ajpregu.00516.2006
-
Wang, C., Bomberg, E., Billington, C., Levine, A. and Kotz, C. M. (2007) Brain-derived neurotrophic factor in the hypothalamic paraventricular nucleus increases energy expenditure by elevating metabolic rate. Am. J. Physiol. Regul. Integr. Comp. Physiol. 293, R992-R1002 (Pubitemid 47358917)
-
(2007)
American Journal of Physiology - Regulatory Integrative and Comparative Physiology
, vol.293
, Issue.3
-
-
Wang, C.1
Bomberg, E.2
Billington, C.3
Levine, A.4
Kotz, C.M.5
-
99
-
-
77952243631
-
Brain-derived neurotrophic factor (BDNF) in the hypothalamic ventromedial nucleus increases energy expenditure
-
Wang, C., Bomberg, E., Billington, C. J., Levine, A. S. and Kotz, C. M. (2010) Brain-derived neurotrophic factor (BDNF) in the hypothalamic ventromedial nucleus increases energy expenditure. Brain Res. 1336, 66-77
-
(2010)
Brain Res.
, vol.1336
, pp. 66-77
-
-
Wang, C.1
Bomberg, E.2
Billington, C.J.3
Levine, A.S.4
Kotz, C.M.5
-
100
-
-
80052739107
-
White to brown fat phenotypic switch induced by genetic and environmental activation of a hypothalamic-adipocyte axis
-
Cao, L., Choi, E. Y., Liu, X., Martin, A., Wang, C., Xu, X. and During, M. J. (2011) White to brown fat phenotypic switch induced by genetic and environmental activation of a hypothalamic-adipocyte axis. Cell Metab. 14, 324-338
-
(2011)
Cell Metab.
, vol.14
, pp. 324-338
-
-
Cao, L.1
Choi, E.Y.2
Liu, X.3
Martin, A.4
Wang, C.5
Xu, X.6
During, M.J.7
-
101
-
-
84879548972
-
Increased mitochondrial activity in BMP7-treated brown adipocytes, due to increased CPT1- and CD36-mediated fatty acid uptake
-
doi:10.1089/ars.2012.4536
-
Townsend, K. L., An, D., Lynes, M. D., Huang, T. L., Zhang, H., Goodyear, L. J. and Tseng, Y. H. (2012) Increased mitochondrial activity in BMP7-treated brown adipocytes, due to increased CPT1- and CD36-mediated fatty acid uptake. Antioxid. Redox. Signaling, doi:10.1089/ars.2012.4536
-
(2012)
Antioxid. Redox. Signaling
-
-
Townsend, K.L.1
An, D.2
Lynes, M.D.3
Huang, T.L.4
Zhang, H.5
Goodyear, L.J.6
Tseng, Y.H.7
-
102
-
-
84860897594
-
Bone morphogenetic protein 7 (BMP7) reverses obesity and regulates appetite through a central mTOR pathway
-
Townsend, K. L., Suzuki, R., Huang, T. L., Jing, E., Schulz, T. J., Lee, K., Taniguchi, CM, Espinoza, D. O., McDougall, L. E., Zhang, H. et al. (2012) Bone morphogenetic protein 7 (BMP7) reverses obesity and regulates appetite through a central mTOR pathway. FASEB J. 26, 2187-2196
-
(2012)
FASEB J.
, vol.26
, pp. 2187-2196
-
-
Townsend, K.L.1
Suzuki, R.2
Huang, T.L.3
Jing, E.4
Schulz, T.J.5
Lee, K.6
Taniguchi, C.M.7
Espinoza, D.O.8
McDougall, L.E.9
Zhang, H.10
-
103
-
-
84860850964
-
BMP8B increases brown adipose tissue thermogenesis through both central and peripheral actions
-
Whittle, A. J., Carobbio, S., Martins, L., Slawik, M., Hondares, E., Vazquez, M. J., Morgan, D., Csikasz, R. I., Gallego, R., Rodriguez-Cuenca, S. et al. (2012) BMP8B increases brown adipose tissue thermogenesis through both central and peripheral actions. Cell 149, 871-885
-
(2012)
Cell
, vol.149
, pp. 871-885
-
-
Whittle, A.J.1
Carobbio, S.2
Martins, L.3
Slawik, M.4
Hondares, E.5
Vazquez, M.J.6
Morgan, D.7
Csikasz, R.I.8
Gallego, R.9
Rodriguez-Cuenca, S.10
-
104
-
-
80053928150
-
Orexin is required for brown adipose tissue development, differentiation, and function
-
Sellayah, D., Bharaj, P. and Sikder, D. (2011) Orexin is required for brown adipose tissue development, differentiation, and function. Cell Metab. 14, 478-490
-
(2011)
Cell Metab.
, vol.14
, pp. 478-490
-
-
Sellayah, D.1
Bharaj, P.2
Sikder, D.3
-
105
-
-
77956030149
-
The endogenous actions of hypothalamic peptides on brown adipose tissue thermogenesis in the rat
-
Verty, A. N., Allen, A. M. and Oldfield, B. J. (2010) The endogenous actions of hypothalamic peptides on brown adipose tissue thermogenesis in the rat. Endocrinology 151, 4236-4246
-
(2010)
Endocrinology
, vol.151
, pp. 4236-4246
-
-
Verty, A.N.1
Allen, A.M.2
Oldfield, B.J.3
-
106
-
-
18844401648
-
Dual regulatory effects of orexins on sympathetic nerve activity innervating brown adipose tissue in rats
-
DOI 10.1210/en.2004-1226
-
Yasuda, T., Masaki, T., Kakuma, T., Hara, M., Nawata, T., Katsuragi, I. and Yoshimatsu, H. (2005) Dual regulatory effects of orexins on sympathetic nerve activity innervating brown adipose tissue in rats. Endocrinology 146, 2744-2748 (Pubitemid 40695578)
-
(2005)
Endocrinology
, vol.146
, Issue.6
, pp. 2744-2748
-
-
Yasuda, T.1
Masaki, T.2
Kakuma, T.3
Hara, M.4
Nawata, T.5
Katsuragi, I.6
Yoshimatsu, H.7
-
107
-
-
78049464825
-
Orexin neurons are indispensable for stress-induced thermogenesis in mice
-
Zhang, W., Sunanaga, J., Takahashi, Y., Mori, T., Sakurai, T., Kanmura, Y. and Kuwaki, T. (2010) Orexin neurons are indispensable for stress-induced thermogenesis in mice. J. Physiol. 588, 4117-4129
-
(2010)
J. Physiol.
, vol.588
, pp. 4117-4129
-
-
Zhang, W.1
Sunanaga, J.2
Takahashi, Y.3
Mori, T.4
Sakurai, T.5
Kanmura, Y.6
Kuwaki, T.7
-
108
-
-
46149086585
-
Central control of thermogenesis in mammals
-
DOI 10.1113/expphysiol.2007.041848
-
Morrison, S. F., Nakamura, K. and Madden, C. J. (2008) Central control of thermogenesis in mammals. Exp. Physiol. 93, 773-797 (Pubitemid 351904256)
-
(2008)
Experimental Physiology
, vol.93
, Issue.7
, pp. 773-797
-
-
Morrison, S.F.1
Nakamura, K.2
Madden, C.J.3
-
109
-
-
79960743932
-
Brown adipose tissue responds to cold and adrenergic stimulation by induction of FGF21
-
Chartoumpekis, D. V., Habeos, I. G., Ziros, P. G., Psyrogiannis, A. I., Kyriazopoulou, V. E. and Papavassiliou, A. G. (2011) Brown adipose tissue responds to cold and adrenergic stimulation by induction of FGF21. Mol. Med. 17, 736-740
-
(2011)
Mol. Med.
, vol.17
, pp. 736-740
-
-
Chartoumpekis, D.V.1
Habeos, I.G.2
Ziros, P.G.3
Psyrogiannis, A.I.4
Kyriazopoulou, V.E.5
Papavassiliou, A.G.6
-
110
-
-
84873854027
-
Brown adipose tissue regulates glucose homeostasis and insulin sensitivity
-
Stanford, K. I., Middelbeek, R. J., Townsend, K. L., An, D., Nygaard, E. B., Hitchcox, K. M., Markan, K. R., Nakano, K., Hirshman, M. F., Tseng, Y. H. and Goodyear, L. J. (2013) Brown adipose tissue regulates glucose homeostasis and insulin sensitivity. J. Clin. Invest. 123, 215-223
-
(2013)
J. Clin. Invest.
, vol.123
, pp. 215-223
-
-
Stanford, K.I.1
Middelbeek, R.J.2
Townsend, K.L.3
An, D.4
Nygaard, E.B.5
Hitchcox, K.M.6
Markan, K.R.7
Nakano, K.8
Hirshman, M.F.9
Tseng, Y.H.10
Goodyear, L.J.11
-
111
-
-
77957279363
-
The T3 receptor β1 isoform regulates UCP1 and D2 deiodinase in rat brown adipocytes
-
Martinez, D. M., Scanlan, T. S. and Obregon, M. J. (2010) The T3 receptor β1 isoform regulates UCP1 and D2 deiodinase in rat brown adipocytes. Endocrinology 151, 5074-5083
-
(2010)
Endocrinology
, vol.151
, pp. 5074-5083
-
-
Martinez, D.M.1
Scanlan, T.S.2
Obregon, M.J.3
-
112
-
-
79955010740
-
Brown adipose tissue growth and development: Significance and nutritional regulation
-
Satterfield, M. C. and Wu, G. (2011) Brown adipose tissue growth and development: significance and nutritional regulation. Front. Biosci. 16, 1589-1608
-
(2011)
Front. Biosci.
, vol.16
, pp. 1589-1608
-
-
Satterfield, M.C.1
Wu, G.2
-
113
-
-
1342282912
-
Differential Roles of Insulin Receptor Substrates in Brown Adipocyte Differentiation
-
DOI 10.1128/MCB.24.5.1918-1929.2004
-
Tseng, Y. H., Kriauciunas, K. M., Kokkotou, E. and Kahn, C. R. (2004) Differential roles of insulin receptor substrates in brown adipocyte differentiation. Mol. Cell. Biol. 24, 1918-1929 (Pubitemid 38248933)
-
(2004)
Molecular and Cellular Biology
, vol.24
, Issue.5
, pp. 1918-1929
-
-
Tseng, Y.-H.1
Kriauciunas, K.M.2
Kokkotou, E.3
Kahn, C.R.4
-
114
-
-
0034783580
-
Brown adipose tissue-specific insulin receptor knockout shows diabetic phenotype without insulin resistance
-
DOI 10.1172/JCI200113103
-
Guerra, C., Navarro, P., Valverde, A. M., Arribas, M., Bruning, J., Kozak, L. P., Kahn, C. R. and Benito, M. (2001) Brown adipose tissue-specific insulin receptor knockout shows diabetic phenotype without insulin resistance. J. Clin. Invest. 108, 1205-1213 (Pubitemid 32995379)
-
(2001)
Journal of Clinical Investigation
, vol.108
, Issue.8
, pp. 1205-1213
-
-
Guerra, C.1
Navarro, P.2
Valverde, A.M.3
Arribas, M.4
Bruning, J.5
Kozak, L.P.6
Kahn, C.R.7
Benito, M.8
-
115
-
-
77249099832
-
Hepatic FGF21 expression is induced at birth via PPARα in response to milk intake and contributes to thermogenic activation of neonatal brown fat
-
Hondares, E., Rosell, M., Gonzalez, F. J., Giralt, M., Iglesias, R. and Villarroya, F. (2010) Hepatic FGF21 expression is induced at birth via PPARα in response to milk intake and contributes to thermogenic activation of neonatal brown fat. Cell Metab. 11, 206-212
-
(2010)
Cell Metab.
, vol.11
, pp. 206-212
-
-
Hondares, E.1
Rosell, M.2
Gonzalez, F.J.3
Giralt, M.4
Iglesias, R.5
Villarroya, F.6
-
116
-
-
79953886306
-
Thermogenic activation induces FGF21 expression and release in brown adipose tissue
-
Hondares, E., Iglesias, R., Giralt, A., Gonzalez, F. J., Giralt, M., Mampel, T. and Villarroya, F. (2011) Thermogenic activation induces FGF21 expression and release in brown adipose tissue. J. Biol. Chem. 286, 12983-12990
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 12983-12990
-
-
Hondares, E.1
Iglesias, R.2
Giralt, A.3
Gonzalez, F.J.4
Giralt, M.5
Mampel, T.6
Villarroya, F.7
-
117
-
-
34249686631
-
Endocrine Regulation of the Fasting Response by PPARα-Mediated Induction of Fibroblast Growth Factor 21
-
DOI 10.1016/j.cmet.2007.05.003, PII S1550413107001301
-
Inagaki, T., Dutchak, P., Zhao, G., Ding, X., Gautron, L., Parameswara, V., Li, Y., Goetz, R., Mohammadi, M., Esser, V. et al. (2007) Endocrine regulation of the fasting response by PPARα-mediated induction of fibroblast growth factor 21. Cell Metab. 5, 415-425 (Pubitemid 46825496)
-
(2007)
Cell Metabolism
, vol.5
, Issue.6
, pp. 415-425
-
-
Inagaki, T.1
Dutchak, P.2
Zhao, G.3
Ding, X.4
Gautron, L.5
Parameswara, V.6
Li, Y.7
Goetz, R.8
Mohammadi, M.9
Esser, V.10
Elmquist, J.K.11
Gerard, R.D.12
Burgess, S.C.13
Hammer, R.E.14
Mangelsdorf, D.J.15
Kliewer, S.A.16
-
118
-
-
34249677947
-
FGF21: A missing link in the biology of fasting
-
Reitman, M. L. (2007) FGF21: a missing link in the biology of fasting. Cell Metab. 5, 405-407
-
(2007)
Cell Metab.
, vol.5
, pp. 405-407
-
-
Reitman, M.L.1
-
119
-
-
84863012022
-
FGF21 regulates PGC-1alpha and browning of white adipose tissues in adaptive thermogenesis
-
Fisher, F. M., Kleiner, S., Douris, N., Fox, E. C., Mepani, R. J., Verdeguer, F., Wu, J., Kharitonenkov, A., Flier, J. S., Maratos-Flier, E. and Spiegelman, B. M. (2012) FGF21 regulates PGC-1alpha and browning of white adipose tissues in adaptive thermogenesis. Genes Dev. 26, 271-281
-
(2012)
Genes Dev.
, vol.26
, pp. 271-281
-
-
Fisher, F.M.1
Kleiner, S.2
Douris, N.3
Fox, E.C.4
Mepani, R.J.5
Verdeguer, F.6
Wu, J.7
Kharitonenkov, A.8
Flier, J.S.9
Maratos-Flier, E.10
Spiegelman, B.M.11
-
120
-
-
84863229962
-
Cardiac natriuretic peptides act via p38 MAPK to induce the brown fat thermogenic program in mouse and human adipocytes
-
Bordicchia, M., Liu, D., Amri, E. Z., Ailhaud, G., Dessi-Fulgheri, P., Zhang, C., Takahashi, N., Sarzani, R. and Collins, S. (2012) Cardiac natriuretic peptides act via p38 MAPK to induce the brown fat thermogenic program in mouse and human adipocytes. J. Clin. Invest. 122, 1022-1036
-
(2012)
J. Clin. Invest.
, vol.122
, pp. 1022-1036
-
-
Bordicchia, M.1
Liu, D.2
Amri, E.Z.3
Ailhaud, G.4
Dessi-Fulgheri, P.5
Zhang, C.6
Takahashi, N.7
Sarzani, R.8
Collins, S.9
-
121
-
-
84862776702
-
A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis
-
Bostrom, P., Wu, J., Jedrychowski, M. P., Korde, A., Ye, L., Lo, J. C., Rasbach, K. A., Bostrom, E. A., Choi, J. H., Long, J. Z. et al. (2012) A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis. Nature 481, 463-468
-
(2012)
Nature
, vol.481
, pp. 463-468
-
-
Bostrom, P.1
Wu, J.2
Jedrychowski, M.P.3
Korde, A.4
Ye, L.5
Lo, J.C.6
Rasbach, K.A.7
Bostrom, E.A.8
Choi, J.H.9
Long, J.Z.10
-
122
-
-
77955333533
-
UCP1 induction during recruitment of brown adipocytes in white adipose tissue is dependent on cyclooxygenase activity
-
Madsen, L., Pedersen, L. M., Lillefosse, H. H., Fjaere, E., Bronstad, I., Hao, Q., Petersen, R. K., Hallenborg, P., Ma, T., De Matteis, R. et al. (2010) UCP1 induction during recruitment of brown adipocytes in white adipose tissue is dependent on cyclooxygenase activity. PLoS ONE 5, e11391
-
(2010)
PLoS ONE
, vol.5
-
-
Madsen, L.1
Pedersen, L.M.2
Lillefosse, H.H.3
Fjaere, E.4
Bronstad, I.5
Hao, Q.6
Petersen, R.K.7
Hallenborg, P.8
Ma, T.9
De Matteis, R.10
-
123
-
-
77952970098
-
Cyclooxygenase-2 controls energy homeostasis in mice by de novo recruitment of brown adipocytes
-
Vegiopoulos, A., Muller-Decker, K., Strzoda, D., Schmitt, I., Chichelnitskiy, E., Ostertag, A., Diaz, M. B., Rozman, J., Hrabe, D. A., Nusing, R. M. et al. (2010) Cyclooxygenase-2 controls energy homeostasis in mice by de novo recruitment of brown adipocytes. Science 328, 1158-1161
-
(2010)
Science
, vol.328
, pp. 1158-1161
-
-
Vegiopoulos, A.1
Muller-Decker, K.2
Strzoda, D.3
Schmitt, I.4
Chichelnitskiy, E.5
Ostertag, A.6
Diaz, M.B.7
Rozman, J.8
Hrabe, D.A.9
Nusing, R.M.10
-
124
-
-
78651313711
-
Nonshivering thermogenesis and its adequate measurement in metabolic studies
-
Cannon, B. and Nedergaard, J. (2011) Nonshivering thermogenesis and its adequate measurement in metabolic studies. J. Exp. Biol. 214, 242-253
-
(2011)
J. Exp. Biol.
, vol.214
, pp. 242-253
-
-
Cannon, B.1
Nedergaard, J.2
-
125
-
-
0024362168
-
Role of thermogenesis in the regulation of energy balance in relation to obesity
-
Himms-Hagen, J. (1989) Role of thermogenesis in the regulation of energy balance in relation to obesity. Can. J. Physiol. Pharmacol. 67, 394-401
-
(1989)
Can. J. Physiol. Pharmacol.
, vol.67
, pp. 394-401
-
-
Himms-Hagen, J.1
-
126
-
-
0023622433
-
Effect of high fat diets on energy balance and thermogenesis in brown adipose tissue of lean and genetically obese ob/ob mice
-
Mercer, S. W. and Trayhurn, P. (1987) Effect of high fat diets on energy balance and thermogenesis in brown adipose tissue of lean and genetically obese ob /ob mice. J. Nutr. 117, 2147-2153 (Pubitemid 18030601)
-
(1987)
Journal of Nutrition
, vol.117
, Issue.12
, pp. 2147-2153
-
-
Mercer, S.W.1
Trayhurn, P.2
-
127
-
-
0018646453
-
A role for brown adipose tissue in diet-induced thermogenesis
-
DOI 10.1038/281031a0
-
Rothwell, N. J. and Stock, M. J. (1979) A role for brown adipose tissue in diet-induced thermogenesis. Nature 281, 31-35 (Pubitemid 9247988)
-
(1979)
Nature
, vol.281
, Issue.5726
, pp. 31-35
-
-
Rothwell, N.J.1
Stock, M.J.2
-
128
-
-
0020693920
-
Luxuskonsumption, diet-induced thermogenesis and brown fat: The case in favour
-
Rothwell, N. J. and Stock, M. J. (1983) Luxuskonsumption, diet-induced thermogenesis and brown fat: the case in favour. Clin. Sci. 64, 19-23 (Pubitemid 13207247)
-
(1983)
Clinical Science
, vol.64
, Issue.1
, pp. 19-23
-
-
Rothwell, N.J.1
Stock, M.J.2
-
129
-
-
84965083278
-
Role of adrenaline and noradrenaline in chemical regulation of heat production
-
Hsieh, A. C. and Alson, L. D. (1957) Role of adrenaline and noradrenaline in chemical regulation of heat production. Am. J. Physiol. 190, 243-246
-
(1957)
Am. J. Physiol.
, vol.190
, pp. 243-246
-
-
Hsieh, A.C.1
Alson, L.D.2
-
130
-
-
0000426830
-
The calorigenic response of cold-acclimated white rats to infused noradrenaline
-
Depocas, F. (1960) The calorigenic response of cold-acclimated white rats to infused noradrenaline. Can. J. Biochem. Physiol. 38, 107-114
-
(1960)
Can. J. Biochem. Physiol.
, vol.38
, pp. 107-114
-
-
Depocas, F.1
-
131
-
-
0028224485
-
Effect of CL-316,243, a thermogenic β3-agonist, on energy balance and brown and white adipose tissues in rats
-
Himms-Hagen, J., Cui, J., Danforth, Jr, E., Taatjes, D. J., Lang, S. S., Waters, B. L. and Claus, T. H. (1994) Effect of CL-316,243, a thermogenic β3-agonist, on energy balance and brown and white adipose tissues in rats. Am. J. Physiol. 266, R1371-R1382
-
(1994)
Am. J. Physiol.
, vol.266
-
-
Himms-Hagen, J.1
Cui, J.2
Danforth Jr., E.3
Taatjes, D.J.4
Lang, S.S.5
Waters, B.L.6
Claus, T.H.7
-
132
-
-
0028237901
-
3- adrenoceptor agonist, in mice with monosodium-L-glutamate-induced obesity
-
Yoshida, T., Sakane, N., Wakabayashi, Y., Umekawa, T. and Kondo, M. (1994) Anti-obesity effect of CL 316,243, a highly specific β3-adrenoceptor agonist, in mice with monosodium-L-glutamate-induced obesity. Eur. J. Endocrinol. 131, 97-102 (Pubitemid 24230559)
-
(1994)
European Journal of Endocrinology
, vol.131
, Issue.1
, pp. 97-102
-
-
Yoshida, T.1
Sakane, N.2
Wakabayashi, Y.3
Umekawa, T.4
Kondo, M.5
-
133
-
-
47149118684
-
The discovery of drugs for obesity, the metabolic effects of leptin and variable receptor pharmacology: Perspectives from β3-adrenoceptor agonists
-
Arch, J. R. (2008) The discovery of drugs for obesity, the metabolic effects of leptin and variable receptor pharmacology: perspectives from β3-adrenoceptor agonists. Naunyn Schmiedebergs Arch. Pharmacol. 378, 225-240
-
(2008)
Naunyn Schmiedebergs Arch. Pharmacol.
, vol.378
, pp. 225-240
-
-
Arch, J.R.1
-
134
-
-
33947678206
-
Thermogenic and metabolic antiobesity drugs: Rationale and opportunities
-
DOI 10.1111/j.1463-1326.2006.00608.x
-
Clapham, J. C. and Arch, J. R. (2007) Thermogenic and metabolic antiobesity drugs: rationale and opportunities. Diabetes Obes. Metab. 9, 259-275 (Pubitemid 46502043)
-
(2007)
Diabetes, Obesity and Metabolism
, vol.9
, Issue.3
, pp. 259-275
-
-
Clapham, J.C.1
Arch, J.R.S.2
-
135
-
-
1842409029
-
Mice lacking mitochondrial uncoupling protein are cold-sensitive but not obese
-
Enerback, S., Jacobsson, A., Simpson, E. M., Guerra, C., Yamashita, H., Harper, M. E. and Kozak, L. P. (1997) Mice lacking mitochondrial uncoupling protein are cold-sensitive but not obese. Nature 387, 90-94 (Pubitemid 27202655)
-
(1997)
Nature
, vol.387
, Issue.6628
, pp. 90-94
-
-
Enerback, S.1
Jacobsson, A.2
Simpson, E.M.3
Guerra, C.4
Yamashita, H.5
Harper, M.-E.6
Kozak, L.P.7
-
136
-
-
23844474515
-
UCP1 deficiency increases susceptibility to diet-induced obesity with age
-
DOI 10.1111/j.1474-9726.2005.00157.x
-
Kontani, Y., Wang, Y., Kimura, K., Inokuma, K. I., Saito, M., Suzuki-Miura, T., Wang, Z., Sato, Y., Mori, N. and Yamashita, H. (2005) UCP1 deficiency increases susceptibility to diet-induced obesity with age. Aging Cell 4, 147-155 (Pubitemid 41602748)
-
(2005)
Aging Cell
, vol.4
, Issue.3
, pp. 147-155
-
-
Kontani, Y.1
Wang, Y.2
Kimura, K.3
Inokuma, K.-I.4
Saito, M.5
Suzuki-Miura, T.6
Wang, Z.7
Sato, Y.8
Mori, N.9
Yamashita, H.10
-
137
-
-
0037314231
-
Paradoxical resistance to diet-induced obesity in UCP1-deficient mice
-
DOI 10.1172/JCI200315737
-
Liu, X., Rossmeisl, M., McClaine, J., Riachi, M., Harper, M. E. and Kozak, L. P. (2003) Paradoxical resistance to diet-induced obesity in UCP1-deficient mice. J. Clin. Invest. 111, 399-407 (Pubitemid 36182217)
-
(2003)
Journal of Clinical Investigation
, vol.111
, Issue.3
, pp. 399-407
-
-
Liu, X.1
Rossmeisl, M.2
McClaine, J.3
Kozak, L.P.4
-
138
-
-
84870265848
-
Sarcolipin is a newly identified regulator of muscle-based thermogenesis in mammals
-
Bal, N. C., Maurya, S. K., Sopariwala, D. H., Sahoo, S. K., Gupta, S. C., Shaikh, S. A., Pant, M., Rowland, L. A., Bombardier, E., Goonasekera, S. A. et al. (2012) Sarcolipin is a newly identified regulator of muscle-based thermogenesis in mammals. Nat. Med. 18, 1575-1579
-
(2012)
Nat. Med.
, vol.18
, pp. 1575-1579
-
-
Bal, N.C.1
Maurya, S.K.2
Sopariwala, D.H.3
Sahoo, S.K.4
Gupta, S.C.5
Shaikh, S.A.6
Pant, M.7
Rowland, L.A.8
Bombardier, E.9
Goonasekera, S.A.10
-
139
-
-
33845977987
-
Genetic variability affects the development of brown adipocytes in white fat but not in interscapular brown fat
-
DOI 10.1194/jlr.M600287-JLR200
-
Xue, B., Rim, J. S., Hogan, J. C., Coulter, A. A., Koza, R. A. and Kozak, L. P. (2007) Genetic variability affects the development of brown adipocytes in white fat but not in interscapular brown fat. J. Lipid Res. 48, 41-51 (Pubitemid 46052896)
-
(2007)
Journal of Lipid Research
, vol.48
, Issue.1
, pp. 41-51
-
-
Xue, B.1
Rim, J.-S.2
Hogan, J.C.3
Coulter, A.A.4
Koza, R.A.5
Kozak, L.P.6
-
140
-
-
79751503329
-
Brown adipose tissue activity controls triglyceride clearance
-
Bartelt, A., Bruns, O. T., Reimer, R., Hohenberg, H., Ittrich, H., Peldschus, K., Kaul, M. G., Tromsdorf, U. I., Weller, H., Waurisch, C. et al. (2011) Brown adipose tissue activity controls triglyceride clearance. Nat. Med. 17, 200-205
-
(2011)
Nat. Med.
, vol.17
, pp. 200-205
-
-
Bartelt, A.1
Bruns, O.T.2
Reimer, R.3
Hohenberg, H.4
Ittrich, H.5
Peldschus, K.6
Kaul, M.G.7
Tromsdorf, U.I.8
Weller, H.9
Waurisch, C.10
-
141
-
-
0036384894
-
Brown adipose tissue: A factor to consider in symmetrical tracer uptake in the neck and upper chest region
-
DOI 10.1007/s00259-002-0902-6
-
Hany, T. F., Gharehpapagh, E., Kamel, E. M., Buck, A., Himms-Hagen, J. and von Schulthess, G. K. (2002) Brown adipose tissue: a factor to consider in symmetrical tracer uptake in the neck and upper chest region. Eur. J. Nucl. Med. Mol. Imaging 29, 1393-1398 (Pubitemid 44392224)
-
(2002)
European Journal of Nuclear Medicine and Molecular Imaging
, vol.29
, Issue.10
, pp. 1393-1398
-
-
Hany, T.F.1
Gharehpapagh, E.2
Kamel, E.M.3
Buck, A.4
Himms-Hagen, J.5
Von Schulthess, G.K.6
-
142
-
-
0037315245
-
Uptake in supraclavicular area fat ("USA-Fat"): Description on 18F-FDG PET/CT
-
Cohade, C., Osman, M., Pannu, H. K. and Wahl, R. L. (2003) Uptake in supraclavicular area fat ("USA-Fat"): description on 18F-FDG PET/CT. J. Nucl. Med. 44, 170-176
-
(2003)
J. Nucl. Med.
, vol.44
, pp. 170-176
-
-
Cohade, C.1
Osman, M.2
Pannu, H.K.3
Wahl, R.L.4
-
143
-
-
70349334680
-
The presence of UCP1 demonstrates that metabolically active adipose tissue in the neck of adult humans truly represents brown adipose tissue
-
Zingaretti, M. C., Crosta, F., Vitali, A., Guerrieri, M., Frontini, A., Cannon, B., Nedergaard, J. and Cinti, S. (2009) The presence of UCP1 demonstrates that metabolically active adipose tissue in the neck of adult humans truly represents brown adipose tissue. FASEB J. 23, 3113-3120
-
(2009)
FASEB J.
, vol.23
, pp. 3113-3120
-
-
Zingaretti, M.C.1
Crosta, F.2
Vitali, A.3
Guerrieri, M.4
Frontini, A.5
Cannon, B.6
Nedergaard, J.7
Cinti, S.8
-
144
-
-
67650242165
-
High incidence of metabolically active brown adipose tissue in healthy adult humans: Effects of cold exposure and adiposity
-
Saito, M., Okamatsu-Ogura, Y., Matsushita, M., Watanabe, K., Yoneshiro, T., Nio-Kobayashi, J., Iwanaga, T., Miyagawa, M., Kameya, T., Nakada, K. et al. (2009) High incidence of metabolically active brown adipose tissue in healthy adult humans: effects of cold exposure and adiposity. Diabetes 58, 1526-1531
-
(2009)
Diabetes
, vol.58
, pp. 1526-1531
-
-
Saito, M.1
Okamatsu-Ogura, Y.2
Matsushita, M.3
Watanabe, K.4
Yoneshiro, T.5
Nio-Kobayashi, J.6
Iwanaga, T.7
Miyagawa, M.8
Kameya, T.9
Nakada, K.10
-
145
-
-
79960945989
-
Different metabolic responses of human brown adipose tissue to activation by cold and insulin
-
Orava, J., Nuutila, P., Lidell, M. E., Oikonen, V., Noponen, T., Viljanen, T., Scheinin, M., Taittonen, M., Niemi, T., Enerback, S. and Virtanen, K. A. (2011) Different metabolic responses of human brown adipose tissue to activation by cold and insulin. Cell Metab. 14, 272-279
-
(2011)
Cell Metab.
, vol.14
, pp. 272-279
-
-
Orava, J.1
Nuutila, P.2
Lidell, M.E.3
Oikonen, V.4
Noponen, T.5
Viljanen, T.6
Scheinin, M.7
Taittonen, M.8
Niemi, T.9
Enerback, S.10
Virtanen, K.A.11
-
146
-
-
84864087999
-
Assessment of oxidative metabolism in brown fat using PET imaging
-
Muzik, O., Mangner, T. J. and Granneman, J. G. (2012) Assessment of oxidative metabolism in brown fat using PET imaging. Front. Endocrin. 3, 15
-
(2012)
Front. Endocrin.
, vol.3
, pp. 15
-
-
Muzik, O.1
Mangner, T.J.2
Granneman, J.G.3
-
147
-
-
84856529575
-
Brown adipose tissue oxidative metabolism contributes to energy expenditure during acute cold exposure in humans
-
Ouellet, V., Labbe, S. M., Blondin, D. P., Phoenix, S., Guerin, B., Haman, F., Turcotte, E. E., Richard, D. and Carpentier, A. C. (2012) Brown adipose tissue oxidative metabolism contributes to energy expenditure during acute cold exposure in humans. J. Clin. Invest. 122, 545-552
-
(2012)
J. Clin. Invest.
, vol.122
, pp. 545-552
-
-
Ouellet, V.1
Labbe, S.M.2
Blondin, D.P.3
Phoenix, S.4
Guerin, B.5
Haman, F.6
Turcotte, E.E.7
Richard, D.8
Carpentier, A.C.9
-
148
-
-
84871898177
-
Characterization of human brown adipose tissue by chemical-shift water-fat MRI
-
Hu, H. H., Perkins, T. G., Chia, J. M. and Gilsanz, V. (2013) Characterization of human brown adipose tissue by chemical-shift water-fat MRI. Am. J. Roentgenol. 200, 177-183
-
(2013)
Am. J. Roentgenol.
, vol.200
, pp. 177-183
-
-
Hu, H.H.1
Perkins, T.G.2
Chia, J.M.3
Gilsanz, V.4
-
149
-
-
84877340732
-
Evidence for two types of brown adipose tissue in humans
-
Lidell, M. E., Betz, M. J., Leinhard, O. D., Heglind, M., Elander, L., Slawik, M., Mussack, T., Nilsson, D., Romu, T., Nuutila, P. et al. (2013) Evidence for two types of brown adipose tissue in humans. Nat. Med. 19, 631-634
-
(2013)
Nat. Med.
, vol.19
, pp. 631-634
-
-
Lidell, M.E.1
Betz, M.J.2
Leinhard, O.D.3
Heglind, M.4
Elander, L.5
Slawik, M.6
Mussack, T.7
Nilsson, D.8
Romu, T.9
Nuutila, P.10
-
150
-
-
0013873889
-
Brown adipose tissue and heat production in the newborn infant
-
Aherne, W. and Hull, D. (1966) Brown adipose tissue and heat production in the newborn infant. J. Pathol. Bacteriol. 91, 223-234
-
(1966)
J. Pathol. Bacteriol.
, vol.91
, pp. 223-234
-
-
Aherne, W.1
Hull, D.2
-
151
-
-
84869233588
-
Human BAT possesses molecular signatures that resemble beige/brite cells
-
Sharp, L. Z., Shinoda, K., Ohno, H., Scheel, D. W., Tomoda, E., Ruiz, L., Hu, H., Wang, L., Pavlova, Z., Gilsanz, V. and Kajimura, S. (2012) Human BAT possesses molecular signatures that resemble beige/brite cells. PLoS ONE 7, e49452
-
(2012)
PLoS ONE
, vol.7
-
-
Sharp, L.Z.1
Shinoda, K.2
Ohno, H.3
Scheel, D.W.4
Tomoda, E.5
Ruiz, L.6
Hu, H.7
Wang, L.8
Pavlova, Z.9
Gilsanz, V.10
Kajimura, S.11
-
152
-
-
84877331455
-
Anatomical localization, gene expression profiling and functional characterization of adult human neck brown fat
-
Cypess, A. M., White, A. P., Vernochet, C., Schulz, T. J., Xue, R., Sass, C. A., Huang, T. L., Roberts-Toler, C., Weiner, L. S., Sze, C. et al. (2013) Anatomical localization, gene expression profiling and functional characterization of adult human neck brown fat. Nat. Med. 19, 635-639
-
(2013)
Nat. Med.
, vol.19
, pp. 635-639
-
-
Cypess, A.M.1
White, A.P.2
Vernochet, C.3
Schulz, T.J.4
Xue, R.5
Sass, C.A.6
Huang, T.L.7
Roberts-Toler, C.8
Weiner, L.S.9
Sze, C.10
|