Pediatric in vitro and in silico models of deposition via oral and nasal inhalation

Journal of Aerosol Medicine and Pulmonary Drug Delivery

Volumn 27, Issue 3, 2014, Pages 149-169

  Carrigy, Nicholas B ^a   Ruzycki, Conor A ^a   Golshahi, Laleh ^b   Finlay, Warren H ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

^b VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

Author keywords

Benchtop models; Child; Computational fluid dynamics; Empirical correlations; Exposure risk assessment; Infant; Inhalation toxicology; Inhaled pharmaceutical aerosol; Mathematical models

Indexed keywords

FLUTICASONE PROPIONATE; NOSE SPRAY; AEROSOL; DRUG; PARTICULATE MATTER;

CHILD; COMPUTATIONAL FLUID DYNAMICS; COMPUTER ASSISTED TOMOGRAPHY; COMPUTER MODEL; DRY POWDER INHALER; FLOW RATE; HUMAN; IN VITRO STUDY; INHALATION; MATHEMATICAL MODEL; MEDICAL NEBULIZER; METERED DOSE INHALER; NUCLEAR MAGNETIC RESONANCE IMAGING; PARTICLE SIZE; REVIEW; RISK ASSESSMENT; SOFT MIST INHALER; ADVERSE EFFECTS; AEROSOL; AGE; ANATOMIC MODEL; ANATOMY AND HISTOLOGY; CHEMISTRY; COMPUTER AIDED DESIGN; COMPUTER SIMULATION; EQUIPMENT DESIGN; EXPOSURE; FEMALE; FLOW KINETICS; GROWTH, DEVELOPMENT AND AGING; INFANT; INHALATIONAL DRUG ADMINISTRATION; INTRANASAL DRUG ADMINISTRATION; MALE; NEBULIZER; ORAL DRUG ADMINISTRATION; PARTICULATE MATTER; PRESCHOOL CHILD; RESPIRATORY SYSTEM;

ADMINISTRATION, INHALATION; ADMINISTRATION, INTRANASAL; ADMINISTRATION, ORAL; AEROSOLS; AGE FACTORS; CHILD; CHILD, PRESCHOOL; COMPUTER SIMULATION; COMPUTER-AIDED DESIGN; EQUIPMENT DESIGN; FEMALE; HUMANS; INFANT; INHALATION EXPOSURE; MALE; MODELS, ANATOMIC; NEBULIZERS AND VAPORIZERS; PARTICLE SIZE; PARTICULATE MATTER; PHARMACEUTICAL PREPARATIONS; RESPIRATORY SYSTEM; RHEOLOGY; RISK ASSESSMENT;

EID: 84901721923     PISSN: 19412711     EISSN: 19412703     Source Type: Journal    
DOI: 10.1089/jamp.2013.1075     Document Type: Review

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