In silico models of aerosol delivery to the respiratory tract - Development and applications

Advanced Drug Delivery Reviews

Volumn 64, Issue 4, 2012, Pages 296-311

  Longest, P Worth ^a,b   Holbrook, Landon T ^a  

^a Virginia Commonwealth University   (United States)

^b VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

Author keywords

1 D models; Aerosol deposition; CFD models; Lung models; Pharmaceutical aerosols; Respiratory drug delivery; Spray momentum; Stochastic individual path (SIP) model; Targeted aerosol delivery; Validation of deposition simulations

Indexed keywords

1-D MODELS; AEROSOL DEPOSITION; CFD MODELS; LUNG MODEL; PHARMACEUTICAL AEROSOLS; SPRAY MOMENTUM; TARGETED AEROSOL DELIVERY; VALIDATION OF DEPOSITION SIMULATIONS;

ATMOSPHERIC AEROSOLS; BIOLOGICAL ORGANS; COMPUTATIONAL FLUID DYNAMICS; DRUG DELIVERY; INTERNET PROTOCOLS; OPTIMIZATION; STOCHASTIC MODELS; STOCHASTIC SYSTEMS;

THREE DIMENSIONAL;

RESPIRATORY TRACT AGENT;

AEROSOL; COMPUTATIONAL FLUID DYNAMICS; COMPUTER MODEL; COMPUTER PREDICTION; COMPUTER SIMULATION; DOSIMETRY; DRUG DELIVERY SYSTEM; DRUG TARGETING; DRUG TRANSPORT; DRY POWDER; HUMAN; LUNG ALVEOLUS; LUNG STRUCTURE; MAGNETIC FIELD; METERED DOSE INHALER; NONHUMAN; PARTICLE SIZE; PRIORITY JOURNAL; PROCESS OPTIMIZATION; RESPIRATORY AIRFLOW; REVIEW; THREE DIMENSIONAL IMAGING; TRACHEOBRONCHIAL TREE; TRANSPORT KINETICS;

ADMINISTRATION, INHALATION; AEROSOLS; COMPUTER SIMULATION; DRUG DELIVERY SYSTEMS; HUMANS; HYDRODYNAMICS; MODELS, BIOLOGICAL; PHARMACEUTICAL PREPARATIONS; RESPIRATORY SYSTEM;

EID: 84858619954     PISSN: 0169409X     EISSN: 18728294     Source Type: Journal    
DOI: 10.1016/j.addr.2011.05.009     Document Type: Review

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