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Volumn 6, Issue 1, 2011, Pages

A Wnt1 regulated Frizzled-1/β-catenin signaling pathway as a candidate regulatory circuit controlling mesencephalic dopaminergic neuron-astrocyte crosstalk: Therapeutical relevance for neuron survival and neuroprotection

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN; CASPASE 3; DOPAMINE TRANSPORTER; FRIZZLED PROTEIN; OXIDOPAMINE; TYROSINE 3 MONOOXYGENASE; WNT1 PROTEIN;

EID: 79960123794     PISSN: None     EISSN: 17501326     Source Type: Journal    
DOI: 10.1186/1750-1326-6-49     Document Type: Article
Times cited : (175)

References (93)
  • 1
    • 0242681988 scopus 로고
    • Idiopathic and 1-methyl-4phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced Parkinsonism
    • Oxford University Press Kettenmann H, Ransom BR
    • Idiopathic and 1-methyl-4phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced Parkinsonism. Di Monte DA, Langston JW, Neuroglia Oxford University Press, Kettenmann H, Ransom BR, 1995 Chapter 65 997 989
    • (1995) Neuroglia , vol.65 , pp. 997-989
    • Di Monte, D.A.1    Langston, J.W.2
  • 2
    • 0348127990 scopus 로고    scopus 로고
    • Neurodegeneration and prospects for neuroprotection and rescue in Parkinson's disease
    • 3
    • Neurodegeneration and prospects for neuroprotection and rescue in Parkinson's disease. Olanow CW, Shapira AHV, Agid Y, Annal Neurology 2003 53 uppl 3
    • (2003) Annal Neurology , vol.53 , pp. 19
    • Olanow, C.W.1    Shapira, A.H.V.2    Agid, Y.3
  • 5
    • 0037378898 scopus 로고    scopus 로고
    • Proteolytic stress: A unifying concept for the etiopathogenesis of Parkinon's disease
    • Proteolytic stress: a unifying concept for the etiopathogenesis of Parkinon's disease. McNaught KSP, Olanow CW, Ann Neurol 2003 53 (3):S73 S86
    • (2003) Ann Neurol , vol.53
    • McNaught, K.S.P.1    Olanow, C.W.2
  • 6
    • 2442636348 scopus 로고    scopus 로고
    • Biomedicine. Parkinson's divergent causes, convergent mechanisms
    • 15155938
    • Biomedicine. Parkinson's divergent causes, convergent mechanisms. Greenamyre JT, Hastings TG, Science 2004 304 (5674):1120 2 15155938
    • (2004) Science , vol.304 , pp. 56741120-2
    • Greenamyre, J.T.1    Hastings, T.G.2
  • 7
    • 18144406539 scopus 로고    scopus 로고
    • Oxidative stress and inflammation in Parkinson's disease: Is there a causal link?
    • DOI 10.1016/j.expneurol.2005.01.013
    • Oxidative stress and inflammation in Parkinson's disease: is there a causal link? Hald A, Lotharaius J, Exp Neurol 2005 193 279 290 10.1016/j.expneurol.2005.01.013 15869932 (Pubitemid 40616179)
    • (2005) Experimental Neurology , vol.193 , Issue.2 , pp. 279-290
    • Hald, A.1    Lotharius, J.2
  • 8
    • 33644543761 scopus 로고    scopus 로고
    • Expanding insights of mitochondrial dysfunction in Parkinson's disease
    • DOI 10.1038/nrn1868, PII N1868
    • Expanding insights of mitochondrial dysfunction in Parkinson's disease. Abou-Sleiman PM, Muqit MM, Wood NW, Nat Rev Neurosci 2006 7 207 219 10.1038/nrn1868 16495942 (Pubitemid 43292466)
    • (2006) Nature Reviews Neuroscience , vol.7 , Issue.3 , pp. 207-219
    • Abou-Sleiman, P.M.1    Muqit, M.M.K.2    Wood, N.W.3
  • 9
    • 62549133546 scopus 로고    scopus 로고
    • Neuroinflammation in Parkinson's disease: A target for neuroprotection?
    • 10.1016/S1474-4422(09)70062-6 19296921
    • Neuroinflammation in Parkinson's disease: a target for neuroprotection? Hirsch EC, Hunot S, Lancet Neurol 2009 8 382 397 10.1016/S1474-4422(09)70062-6 19296921
    • (2009) Lancet Neurol , vol.8 , pp. 382-397
    • Hirsch, E.C.1    Hunot, S.2
  • 11
    • 21744439129 scopus 로고    scopus 로고
    • Glia-Neuron Crosstalk in Neuroinflammation, Neurodegeneration and Neuroprotection
    • Glia-Neuron Crosstalk in Neuroinflammation, Neurodegeneration and Neuroprotection. Marchetti B, Kettenmann H, Streit WJ, Brain Res Review S Issue 2005 482 2 129 32
    • (2005) Brain Res Review S Issue , vol.482 , Issue.2 , pp. 129-32
    • Marchetti, B.1    Kettenmann, H.2    Streit, W.J.3
  • 12
    • 47749126515 scopus 로고    scopus 로고
    • Why neurodegenerative diseases are progressive: Uncontrolled inflammation drives disease progression
    • 10.1016/j.it.2008.05.002 18599350
    • Why neurodegenerative diseases are progressive: uncontrolled inflammation drives disease progression. Gao HM, Hong JS, Trends Immunol 2008 29 8 357 65 10.1016/j.it.2008.05.002 18599350
    • (2008) Trends Immunol , vol.29 , Issue.8 , pp. 357-65
    • Gao, H.M.1    Hong, J.S.2
  • 13
    • 25144468525 scopus 로고    scopus 로고
    • To be or not to be (inflamed) - Is that the question in anti-inflammatory drug therapy of neurodegenerative disorders?
    • DOI 10.1016/j.tips.2005.08.007, PII S0165614705002051
    • To be or not to be (inflammed) is that the question in anti-inflammatory drug therapy of neurodegenerative diseases? Marchetti B, Abbracchio MP, Trends in Pharmacological Sci 2005 26 517 525 10.1016/j.tips.2005.08.007 (Pubitemid 41338562)
    • (2005) Trends in Pharmacological Sciences , vol.26 , Issue.10 , pp. 517-525
    • Marchetti, B.1    Abbracchio, M.P.2
  • 14
    • 47349104402 scopus 로고    scopus 로고
    • Glial reactions in Parkinson's disease
    • 10.1002/mds.21751 18044695
    • Glial reactions in Parkinson's disease. McGeer PL, McGeer EG, Mov Disord 2008 23 474 483 10.1002/mds.21751 18044695
    • (2008) Mov Disord , vol.23 , pp. 474-483
    • McGeer, P.L.1    McGeer, E.G.2
  • 15
    • 2642542373 scopus 로고    scopus 로고
    • Pro-regenerative properties of cytokine-activated astrocytes
    • DOI 10.1111/j.1471-4159.2004.02420.x
    • Pro-regenerative properties of cytokine-activated astrocytes. Liberto CM, Albrecht PJ, Herx LM, Yong VW, Levison SW, J Neurochem 2004 89 1092 100 10.1111/j.1471-4159.2004.02420.x 15147501 (Pubitemid 38715826)
    • (2004) Journal of Neurochemistry , vol.89 , Issue.5 , pp. 1092-1100
    • Liberto, C.M.1    Albrecht, P.J.2    Herx, L.M.3    Yong, V.W.4    Levison, S.W.5
  • 16
    • 62449132771 scopus 로고    scopus 로고
    • Nrf2-mediated neuroprotection in the MPTP mouse model of Parkinson's disease: Critical role for the astrocyte
    • 10.1073/pnas.0813361106 19196989
    • Nrf2-mediated neuroprotection in the MPTP mouse model of Parkinson's disease: Critical role for the astrocyte. Chen PC, Vargas MR, Pani AK, Smeyne RJ, Johnson DA, Kan YW, Johnson JA, PNAS 2009 106 8 2933 2938 10.1073/pnas.0813361106 19196989
    • (2009) PNAS , vol.106 , Issue.8 , pp. 2933-2938
    • Chen, P.C.1    Vargas, M.R.2    Pani, A.K.3    Smeyne, R.J.4    Johnson, D.A.5    Kan, Y.W.6    Johnson, J.A.7
  • 18
    • 0034993599 scopus 로고    scopus 로고
    • Molecular pathways involved in the neurotoxicity of 6-OHDA, dopamine and MPTP: Contribution to the apoptotic theory in Parkinson's disease
    • DOI 10.1016/S0301-0082(01)00003-X, PII S030100820100003X
    • Molecular pathways involved in the neurotoxicity of 6-OHDA, dopamine and MPTP: contribution to the apoptotic theory in Parkinson's disease. Blum D, Torch S, Lambeng N, Nissou MF, Benabid AL, Sadoul R, Verna JM, Prog in Neurobiol 2001 65 135 172 10.1016/S0301-0082(01)00003-X (Pubitemid 32524182)
    • (2001) Progress in Neurobiology , vol.65 , Issue.2 , pp. 135-172
    • Blum, D.1    Torch, S.2    Lambeng, N.3    Nissou, M.-F.4    Benabid, A.-L.5    Sadoul, R.6    Verna, J.-M.7
  • 19
    • 34347259269 scopus 로고    scopus 로고
    • Protocol for the MPTP mouse model of Parkinson's disease
    • DOI 10.1038/nprot.2006.342, PII NPROT.2006.342
    • Protocol for the MPTP model of Parkinson's disease. Jackson-Lewis V, Przedborski S, Nature Protocols 2007 2 1 141 151 10.1038/nprot.2006.342 17401348 (Pubitemid 47044700)
    • (2007) Nature Protocols , vol.2 , Issue.1 , pp. 141-151
    • Jackson-Lewis, V.1    Przedborski, S.2
  • 20
    • 0034084768 scopus 로고    scopus 로고
    • Roles of Wnt proteins in neural development and maintenance
    • DOI 10.1016/S0959-4388(00)00100-8
    • Roles of Wnt proteins in neural development and maintenance. Patapoutian A, Reichardt LF, Curr Opin Neurobiol 2000 10 3 392 399 10.1016/S0959-4388(00) 00100-8 10851180 (Pubitemid 30389308)
    • (2000) Current Opinion in Neurobiology , vol.10 , Issue.3 , pp. 392-399
    • Patapoutian, A.1    Reichardt, L.F.2
  • 21
    • 17844366846 scopus 로고    scopus 로고
    • WNTs in the vertebrate nervous system: From patterning to neuronal connectivity
    • DOI 10.1038/nrn1665
    • WNTs in the vertebrate nervous system: From patterning to neuronal connectivity. Ciani L, Salinas PC, Nat Rev Neurosci 2005 6 351 362 15832199 (Pubitemid 40593481)
    • (2005) Nature Reviews Neuroscience , vol.6 , Issue.5 , pp. 351-362
    • Ciani, L.1    Salinas, P.C.2
  • 24
    • 48749133346 scopus 로고    scopus 로고
    • Wnt signaling in neuroprotection and stem cell differentiation
    • Wnt signaling in neuroprotection and stem cell differentiation. Toledo EM, Clombres M, Inestrosa NC, Progr Neurobiol 2008 88 281 296
    • (2008) Progr Neurobiol , vol.88 , pp. 281-296
    • Toledo, E.M.1    Clombres, M.2    Inestrosa, N.C.3
  • 25
    • 77249109792 scopus 로고    scopus 로고
    • Activation of Wnt signaling by lithium and rosiglitazone reduced spatial memory impairment and neurodegeneration in brains of an APPswe/PSEN1DeltaE9 mouse model of Alzheimer's disease
    • 10.1038/mp.2009.72 19621015
    • Activation of Wnt signaling by lithium and rosiglitazone reduced spatial memory impairment and neurodegeneration in brains of an APPswe/PSEN1DeltaE9 mouse model of Alzheimer's disease. Toledo EM, Inestrosa NC, Mol Psychiatry 2010 15 272 285 10.1038/mp.2009.72 19621015
    • (2010) Mol Psychiatry , vol.15 , pp. 272-285
    • Toledo, E.M.1    Inestrosa, N.C.2
  • 26
    • 34147100616 scopus 로고    scopus 로고
    • Cellular demise and inflammatory microglial activation during β-amyloid toxicity are governed by Wnt1 and canonical signaling pathways
    • DOI 10.1016/j.cellsig.2006.12.009, PII S089865680600341X
    • Cellular demise and inflammatory microglial activation during -amyloid toxicity are governed by WNT1 and canonical signaling pathways. Chong ZZ, Li F, Maiese K, Cell Signal 2007 19 6 1150 1162 10.1016/j.cellsig.2006.12.009 17289346 (Pubitemid 46561553)
    • (2007) Cellular Signalling , vol.19 , Issue.6 , pp. 1150-1162
    • Chong, Z.Z.1    Li, F.2    Maiese, K.3
  • 27
    • 42649140551 scopus 로고    scopus 로고
    • The Wnt signalling pathway: Aging gracefully as a protectionist?
    • 10.1016/j.pharmthera.2008.01.004 18313758
    • The Wnt signalling pathway: aging gracefully as a protectionist? Maiese K, Faqi L, Chong ZZ, Chen SY, Pharmacol Ther 2008 118 1 58 81 10.1016/j.pharmthera.2008.01.004 18313758
    • (2008) Pharmacol Ther , vol.118 , Issue.1 , pp. 58-81
    • Maiese, K.1    Faqi, L.2    Chong, Z.Z.3    Chen, S.Y.4
  • 28
    • 49649094091 scopus 로고    scopus 로고
    • The role of Wnt signalling in neuronal dysfunction in Alzheimer's disease
    • 10.1186/1750-1326-3-9
    • The role of Wnt signalling in neuronal dysfunction in Alzheimer's disease. Inestrosa NC, Toledo EM, Mol Neurodegen 2008 3 9 10.1186/1750-1326-3-9
    • (2008) Mol Neurodegen , vol.3 , pp. 9
    • Inestrosa, N.C.1    Toledo, E.M.2
  • 29
    • 75549087261 scopus 로고    scopus 로고
    • Emerging role of Wnts in the adult nervous system
    • 20010950
    • Emerging role of Wnts in the adult nervous system. Inestrosa NC, Arenas E, Nat Rev Neurosci 2009 11 2 77 86 20010950
    • (2009) Nat Rev Neurosci , vol.11 , Issue.2 , pp. 77-86
    • Inestrosa, N.C.1    Arenas, E.2
  • 31
    • 33747339465 scopus 로고    scopus 로고
    • Wnt signaling: Multiple pathways, multiple receptors, and multiple transcription factors
    • 10.1074/jbc.R600015200 16793760
    • Wnt signaling: Multiple pathways, multiple receptors, and multiple transcription factors. Gordon MD, Nusse R, J Biol Chem 2006 281 22429 22433 10.1074/jbc.R600015200 16793760
    • (2006) J Biol Chem , vol.281 , pp. 22429-22433
    • Gordon, M.D.1    Nusse, R.2
  • 32
    • 0030978351 scopus 로고    scopus 로고
    • β-Catenin is a target for the ubiquitin-proteasome pathway
    • DOI 10.1093/emboj/16.13.3797
    • Beta-catenin is a target for the ubiquitin-proteasome pathway. Aberle H, Bauer A, Stappert J, Kispert A, Kemler R, EMBO J 1997 16 13 3797 804 10.1093/emboj/16.13.3797 9233789 (Pubitemid 27280995)
    • (1997) EMBO Journal , vol.16 , Issue.13 , pp. 3797-3804
    • Aberle, H.1    Bauer, A.2    Stappert, J.3    Kispert, A.4    Kemler, R.5
  • 34
    • 12344307661 scopus 로고    scopus 로고
    • GSK-3β inhibition/β-catenin stabilization in ventral midbrain precursors increases differentiation into dopamine neurons
    • DOI 10.1242/jcs.01505
    • GSK-3 inhibition/-catenin stabilization in ventral midbrain precursors increases differentiation into dopamine neurons. Castelo-Branco G, Rawal N, Arenas E, J of Cell Sci 2004 117 5731 5737 10.1242/jcs.01505 (Pubitemid 40123940)
    • (2004) Journal of Cell Science , vol.117 , Issue.24 , pp. 5731-5737
    • Castelo-Branco, G.1    Rawal, N.2    Arenas, E.3
  • 35
    • 32244442041 scopus 로고    scopus 로고
    • Ventral midbrain glia express region-specific transcription factors and regulate dopaminergic neurogenesis through Wnt-5a secretion
    • DOI 10.1016/j.mcn.2005.09.014, PII S1044743105002307
    • Ventral midbrain glia express region-specific transcription factors and regulate dopaminergic neurogenesis through Wnt-5a secretion. Castelo-Branco G, Sousa KM, Bryja V, Pinto L, Wagner J, Arenas E, Mol Cell Neurosci 2006 31 2 251 262 10.1016/j.mcn.2005.09.014 16243537 (Pubitemid 43214535)
    • (2006) Molecular and Cellular Neuroscience , vol.31 , Issue.2 , pp. 251-262
    • Castelo-Branco, G.1    Sousa, K.M.2    Bryja, V.3    Pinto, L.4    Wagner, J.5    Arenas, E.6
  • 36
    • 33747670219 scopus 로고    scopus 로고
    • Genetic networks controlling the development of midbrain dopaminergic neurons
    • DOI 10.1113/jphysiol.2006.113464
    • Genetic networks controlling the development of midbrain dopaminergic neurons. Prakash N, Wurst W, J Physiol 2006 575 403 410 10.1113/jphysiol.2006. 113464 16825303 (Pubitemid 44270171)
    • (2006) Journal of Physiology , vol.575 , Issue.2 , pp. 403-410
    • Prakash, N.1    Wurst, W.2
  • 37
    • 33646133416 scopus 로고    scopus 로고
    • Dynamic temporal and cell type-specific expression of Wnt signaling components in the developing midbrain
    • 10.1016/j.yexcr.2006.01.032 16510140
    • Dynamic temporal and cell type-specific expression of Wnt signaling components in the developing midbrain. Rawal N, Castelo-Branco G, Souse KM, Kele J, Kobayashy K, Okano H, Arenas E, Exp Cell Res 2006 312 1626 1636 10.1016/j.yexcr.2006.01.032 16510140
    • (2006) Exp Cell Res , vol.312 , pp. 1626-1636
    • Rawal, N.1    Castelo-Branco, G.2    Souse, K.M.3    Kele, J.4    Kobayashy, K.5    Okano, H.6    Arenas, E.7
  • 39
    • 84863116750 scopus 로고    scopus 로고
    • Critical role of microglial NADPH oxidase-derived free radicals in the in vitro MPTP model of Parkinson's disease
    • 12897068
    • Critical role of microglial NADPH oxidase-derived free radicals in the in vitro MPTP model of Parkinson's disease. Gao HM, Liu B, Zhang W, Hong JS, FASEB J 2003 17 13 1954 1956 12897068
    • (2003) FASEB J , vol.17 , Issue.13 , pp. 1954-1956
    • Gao, H.M.1    Liu, B.2    Zhang, W.3    Hong, J.S.4
  • 40
    • 0035954281 scopus 로고    scopus 로고
    • Head inducer dickkopf-1 is a ligand for Wnt coreceptor LRP6
    • DOI 10.1016/S0960-9822(01)00290-1
    • Head inducer Dickkopf-1 is a ligand for Wnt coreceptor LRP6. Semnov MV, Tamai K, Brott BK, Kühl M, Sokol S, He X, Curr Biol 2001 11 12 951 961 10.1016/S0960-9822(01)00290-1 11448771 (Pubitemid 32589186)
    • (2001) Current Biology , vol.11 , Issue.12 , pp. 951-961
    • Semenov, M.V.1    Tamai, K.2    Brott, B.K.3    Kuhl, M.4    Sokol, S.5    He, X.6
  • 41
    • 0035811492 scopus 로고    scopus 로고
    • Insights into Wnt binding and signalling from the structures of two Frizzled cysteine-rich domains
    • DOI 10.1038/35083601
    • Insights into Wnt binding and signalling from the structures of two Frizzled cysteine-rich domains. Dann CE, Hsieh JC, Rattner A, Sharma D, Nathans J, Leahy DJ, Nature 2001 412 86 90 10.1038/35083601 11452312 (Pubitemid 32851515)
    • (2001) Nature , vol.412 , Issue.6842 , pp. 86-90
    • Dann, C.E.1    Hsieh, J.-C.2    Rattner, A.3    Sharma, D.4    Nathans, J.5    Leahy, D.J.6
  • 42
    • 34247140309 scopus 로고    scopus 로고
    • Wnt signaling promotes regeneration in the retina of adult mammals
    • DOI 10.1523/JNEUROSCI.4193-06.2007
    • Wnt signalling promotes regeneration in the retina of adult mammals. Osakada F, Ooto S, Akagi T, Mandai M, Akaike A, Takahashi M, J of Neurosci 2007 27 15 4210 4219 10.1523/JNEUROSCI.4193-06.2007 (Pubitemid 46597155)
    • (2007) Journal of Neuroscience , vol.27 , Issue.15 , pp. 4210-4219
    • Osakada, F.1    Ooto, S.2    Akagi, T.3    Mandai, M.4    Akaike, A.5    Takahashi, M.6
  • 43
  • 44
    • 0031456672 scopus 로고
    • Interaction of Wnt and a inositol signalling
    • Interaction of Wnt and a inositol signalling. Slusarski DC, Corces VG, Moon RT, Nature 1976 390 410 413
    • (1976) Nature , vol.390 , pp. 410-413
    • Slusarski, D.C.1    Corces, V.G.2    Moon, R.T.3
  • 45
    • 0033166245 scopus 로고    scopus 로고
    • Protein kinase C is differentially stimulated by Wnt and Frizzled homologs in a G-protein-dependent manner
    • DOI 10.1016/S0960-9822(99)80310-8
    • Protein kinase Cis differentially stimulated by Wnt and Frizzled homologs in a G-protein -dependent manner. Shedahl LC, Park M, Malbon CC, Moon RT, Curr Biol 1999 9 695 698 10.1016/S0960-9822(99)80310-8 10395542 (Pubitemid 29332351)
    • (1999) Current Biology , vol.9 , Issue.13 , pp. 695-698
    • Sheldahl, L.C.1    Park, M.2    Malbon, C.C.3    Moon, R.T.4
  • 46
    • 0034659602 scopus 로고    scopus 로고
    • Basic fibroblast growth factor (bFGF) acts on both neurons and glia to mediate the neurotrophic effects of astrocytes on LHRH neurons in culture
    • DOI 10.1002/(SICI)1098-2396(20000615)36:4<233::AID-SYN1>3.0.CO;2-I
    • Basic fibroblast growth factor (bFGF) acts on both neurons and glia to mediate the neurotrophic effects of astrocytes on LHRH neurons in culture. Gallo F, Morale MC, Spina-Purrello V, Tirolo C, Testa N, Farinella Z, Avola R, Beaudet A, Marchetti B, Synapse 2000 36 233 253 10.1002/(SICI)1098- 2396(20000615)36:4<233::AID-SYN1>3.0.CO;2-I 10819902 (Pubitemid 30257309)
    • (2000) Synapse , vol.36 , Issue.4 , pp. 233-253
    • Gallo, F.1    Morale, M.C.2    Spina-Purrello, V.3    Tirolo, C.4    Testa, N.5    Farinella, Z.6    Avola, R.7    Beaudet, A.8    Marchetti, B.9
  • 47
    • 0033825066 scopus 로고    scopus 로고
    • Basic fibroblast growth factor priming increases the responsiveness of immortalized hypothalamic luteinizing hormone releasing hormone neurones to neurotrophic factors
    • 11012835
    • Basic fibroblast growth factor priming increases the responsiveness of immortalized hypothalamic luteinizing hormone releasing hormone neurones to neurotrophic factors. Gallo F, Morale MC, Tirolo C, Testa N, Farinella Z, Avola R, Beaudet A, Marchetti B, J Neuroendocrinol 2000 12 10 941 59 11012835
    • (2000) J Neuroendocrinol , vol.12 , Issue.10 , pp. 941-59
    • Gallo, F.1    Morale, M.C.2    Tirolo, C.3    Testa, N.4    Farinella, Z.5    Avola, R.6    Beaudet, A.7    Marchetti, B.8
  • 49
    • 11844269265 scopus 로고    scopus 로고
    • Delivery of small interfering RNA to mammalian cells in culture by using cationic lipid/polymer-based transfection reagents
    • DOI 10.1016/S0076-6879(04)92007-1, PII S0076687904920071
    • Delivery of small interfering RNA to mammalian cells in culture by using cationic lipid/polymer-based transfection reagents. Brazas RM, Hagstrom JE, Methods Enzymol 2005 392 112 124 15644178 (Pubitemid 40092511)
    • (2005) Methods in Enzymology , vol.392 , pp. 112-124
    • Brazas, R.M.1    Hagstrom, J.E.2
  • 50
    • 50649109669 scopus 로고    scopus 로고
    • Msx2 exerts bone anabolism via canonical Wnt signaling
    • 10.1074/jbc.M800851200 18487199
    • Msx2 exerts bone anabolism via canonical Wnt signaling. Cheng SL, Shao JS, Cai J, Sierra OL, Towler DA, J Biol Chem 2008 283 29 20505 22 10.1074/jbc.M800851200 18487199
    • (2008) J Biol Chem , vol.283 , Issue.29 , pp. 20505-22
    • Cheng, S.L.1    Shao, J.S.2    Cai, J.3    Sierra, O.L.4    Towler, D.A.5
  • 51
    • 49649088889 scopus 로고    scopus 로고
    • Frizzled-1 is involved in the neuroprotective effect of Wnt3a against Abeta oligomers
    • 10.1002/jcp.21497 18521822
    • Frizzled-1 is involved in the neuroprotective effect of Wnt3a against Abeta oligomers. Chacán MA, Varela-Nallar L, Inestrosa NC, J Cell Physiol 2008 217 1 215 27 10.1002/jcp.21497 18521822
    • (2008) J Cell Physiol , vol.217 , Issue.1 , pp. 215-27
    • Chacán, M.A.1    Varela-Nallar, L.2    Inestrosa, N.C.3
  • 52
    • 66249086574 scopus 로고    scopus 로고
    • Interruption of -catenin signaling reduces neurogenesis in Alzheimer's disease
    • 10.1523/JNEUROSCI.0421-09.2009 19458225
    • Interruption of -catenin signaling reduces neurogenesis in Alzheimer's disease. He P, Shen Y, J Neurosci 2009 29 6545 6557 10.1523/JNEUROSCI.0421-09. 2009 19458225
    • (2009) J Neurosci , vol.29 , pp. 6545-6557
    • He, P.1    Shen, Y.2
  • 55
    • 34249689633 scopus 로고    scopus 로고
    • Inhibition of glycogen synthase kinase-3β protects dopaminergic neurons from MPTP toxicity
    • DOI 10.1016/j.neuropharm.2007.03.017, PII S0028390807000962
    • Inhibition of glycogen synthase kinase-3 protects dopaminergic neurons from MPTP toxicity. Wang W, Yang Y, Ying C, Li W, Ruan H, Zhu X, You Y, Han Y, Chen R, Wang Y, Li M, Neuropharmacology 2007 52 1678 1684 10.1016/j.neuropharm. 2007.03.017 17517424 (Pubitemid 46843143)
    • (2007) Neuropharmacology , vol.52 , Issue.8 , pp. 1678-1684
    • Wang, W.1    Yang, Y.2    Ying, C.3    Li, W.4    Ruan, H.5    Zhu, X.6    You, Y.7    Han, Y.8    Chen, R.9    Wang, Y.10    Li, M.11
  • 56
    • 0030901162 scopus 로고    scopus 로고
    • Fluoro-Jade: A novel fluorochrome for the sensitive and reliable histochemical localization of neuronal degeneration
    • DOI 10.1016/S0006-8993(96)01387-X, PII S000689939601387X
    • Fluoro-Jade: a novel fluorochrome for the sensitive and relialable histochemical localization of neuronal degeneration. Schmued LC, Albertston C, Slikker W Jr, Brain Res 1997 751 37 46 10.1016/S0006-8993(96)01387-X 9098566 (Pubitemid 27122134)
    • (1997) Brain Research , vol.751 , Issue.1 , pp. 37-46
    • Schmued, L.C.1    Albertson, C.2    Slikker Jr., W.3
  • 57
    • 0028111551 scopus 로고
    • Mesencephalic type 1 astrocytes rescue dopaminergic neurons from death induced by serum deprivation
    • Mesencephalic type 1 astrocytes rescue dopaminergic neurons from death induced by serum deprivation. Takeshima T, Johnston JM, Commissiong JW, J Neurosci 1994 14 4769 4779 7913955 (Pubitemid 24237899)
    • (1994) Journal of Neuroscience , vol.14 , Issue.8 , pp. 4769-4779
    • Takeshima, T.1    Johnston, J.M.2    Commissiong, J.W.3
  • 58
    • 0034235776 scopus 로고    scopus 로고
    • Wnt-1 dependent activation of the survival factor NF-κB in PC12 cells
    • Wnt-1 dependent activation of the survival factor NF-kappaB in PC12 cells. Bournat JC, Brown AM, Soler AP, J Neurosci Res 2000 61 1 21 32 10.1002/1097-4547(20000701)61:1<21::AID-JNR3>3.0.CO;2-7 10861796 (Pubitemid 30436471)
    • (2000) Journal of Neuroscience Research , vol.61 , Issue.1 , pp. 21-32
    • Bournat, J.C.1    Brown, A.M.C.2    Soler, A.P.3
  • 59
    • 0037064055 scopus 로고    scopus 로고
    • Wnt signaling protects 3T3-L1 preadipocytes from apoptosis through induction of insulin-like growth factors
    • DOI 10.1074/jbc.M206402200
    • Wnt signalling protects 3T3-L1 preadipocytes from apoptosis through induction of insulin-like growth factors. Longo KA, Kennell JA, Ochocinska MJ, Ross SE, Wright WS, MacDougald OA, J of Biol Chem 2002 277 38239 38244 10.1074/jbc.M206402200 (Pubitemid 35154678)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.41 , pp. 38239-38244
    • Longo, K.A.1    Kennell, J.A.2    Ochocinska, M.J.3    Ross, S.E.4    Wright, W.S.5    MacDougald, O.A.6
  • 61
    • 0035900197 scopus 로고    scopus 로고
    • Caspase-3 activation induced by inhibition of mitochondrial complex I is facilitated by glycogen synthase kinase-3β and attenuated by lithium
    • DOI 10.1016/S0006-8993(01)03005-0, PII S0006899301030050
    • Caspase-3 activation induced by inhibition of mitochondrial complex I is facilitated by glycogen synthase kinase-3 and attenuated by lithium. King TD, Bijur GN, Jope RS, Brain Res 2001 919 106 114 10.1016/S0006-8993(01)03005-0 11689167 (Pubitemid 33016593)
    • (2001) Brain Research , vol.919 , Issue.1 , pp. 106-114
    • King, T.D.1    Bijur, G.N.2    Jope, R.S.3
  • 62
  • 63
    • 9444257518 scopus 로고    scopus 로고
    • Glycogen synthase kinase 3β (GSK3β) mediates 6-hydroxydopamine- induced neuronal death
    • DOI 10.1096/fj.04-1551fje
    • Glycogen synthase kinase 3beta (GSK3beta) mediates 6-hydroxy dopamine-induced neuronal death. Chen G, Bower KA, Ma C, Ma C, Fang S, Thiele CJ, Luo J, Faseb J 2004 18 1162 1164 15132987 (Pubitemid 39561557)
    • (2004) FASEB Journal , vol.18 , Issue.10 , pp. 1162-1164
    • Chen, G.1    Bower, K.A.2    Ma, C.3    Fang, S.4    Thiele, C.J.5    Luo, J.6
  • 64
    • 47249083512 scopus 로고    scopus 로고
    • Differential modulation of Akt/Glycogen synthase kinase-3beta pathway regulates apoptotic and cytoprotective signalling responses
    • 10.1074/jbc.M707238200 18387957
    • Differential modulation of Akt/Glycogen synthase kinase-3beta pathway regulates apoptotic and cytoprotective signalling responses. Nair VD, Olanow CW, J Biol Chem 2008 283 22 15469 15478 10.1074/jbc.M707238200 18387957
    • (2008) J Biol Chem , vol.283 , Issue.22 , pp. 15469-15478
    • Nair, V.D.1    Olanow, C.W.2
  • 65
    • 65549123313 scopus 로고    scopus 로고
    • +- treated neurons
    • 10.1371/journal.pone.0005491 19430525
    • +- treated neurons. Petit-Paitel A, Brau F, Cazareth J. Chabry J, Plos One 2009 4 5 5491 10.1371/journal.pone.0005491 19430525
    • (2009) Plos One , vol.4 , Issue.5 , pp. 55491
    • Petit-Paitel, A.1    Brau, F.2    Cazareth Chabry J, J.3
  • 66
    • 70349331692 scopus 로고    scopus 로고
    • -Synuclein contributes to GSK-3- catalyzed Tau phosphorylation in Parkinson's disease models
    • 10.1096/fj.08-120410 19369384
    • -Synuclein contributes to GSK-3- catalyzed Tau phosphorylation in Parkinson's disease models. Duka T, Duka V, Joyce JN, Sidhu A, Faseb J 2009 23 9 2820 2830 10.1096/fj.08-120410 19369384
    • (2009) Faseb J , vol.23 , Issue.9 , pp. 2820-2830
    • Duka, T.1    Duka, V.2    Joyce, J.N.3    Sidhu, A.4
  • 67
    • 0034859101 scopus 로고    scopus 로고
    • The multifaceted roles of glycogen synthase kinase 3β in cellular signaling
    • DOI 10.1016/S0301-0082(01)00011-9, PII S0301008201000119
    • The multifaceted roles of glycogen synthase kinase 3beta in cellular signaling. Grimes CA, Jope RS, Prog Neurobiol 2001 65 4 391 426 10.1016/S0301-0082(01)00011-9 11527574 (Pubitemid 32781670)
    • (2001) Progress in Neurobiology , vol.65 , Issue.4 , pp. 391-426
    • Grimes, C.A.1    Jope, R.S.2
  • 68
    • 0026042368 scopus 로고
    • The neurotrophic effects of fibroblast growth factors on dopaminergic neurons in vitro are mediated by mesencephalic glia
    • 1941074
    • The neurotrophic effects of fibroblast growth factors on dopaminergic neurons in vitro are mediated by mesencephalic glia. Engele J, Bohn MC, J Neurosci 1991 11 10 3070 3078 1941074
    • (1991) J Neurosci , vol.11 , Issue.10 , pp. 3070-3078
    • Engele, J.1    Bohn, M.C.2
  • 69
    • 0001969422 scopus 로고    scopus 로고
    • Cross-talk signals in the CNS: Role of neurotrophic and hormonal factors, adhesion molecules and intercellular signaling agents in luteinizing hormone-releasing hormone (LHRH) neuron-astroglia interactive network
    • Cross-talk signals in the CNS: Role of neurotrophic and hormonal factors, adhesion molecules and intercellular signaling agents in luteinizing hormone-releasing hormone (LHRH) neuron-astroglia interactive network. Marchetti B, Trends in Biosci 1997 2 1 32
    • (1997) Trends in Biosci , vol.2 , pp. 1-32
    • Marchetti, B.1
  • 70
    • 0033899176 scopus 로고    scopus 로고
    • Glutathione metabolism in brain: Metabolic interaction between astrocytes and neurons in the defense against reactive oxygen species
    • DOI 10.1046/j.1432-1327.2000.01597.x
    • Glutathione metabolism in brain. Metabolic interaction between astrocytes and neurons in the defense against reactive oxygen species. Dringen J, Gutterer M, Hirrlinger J, Eur J of Biochem 2000 267 4912 4916 (Pubitemid 30641287)
    • (2000) European Journal of Biochemistry , vol.267 , Issue.16 , pp. 4912-4916
    • Dringen, R.1    Gutterer, J.M.2    Hirrlinger, J.3
  • 71
    • 77649189116 scopus 로고    scopus 로고
    • Astrocytes: Biology and pathology
    • 10.1007/s00401-009-0619-8
    • Astrocytes: biology and pathology. Sofroniew M, Vinters HB, Act Neuropatology 2010 119 7 35 10.1007/s00401-009-0619-8
    • (2010) Act Neuropatology , vol.119 , pp. 7-35
    • Sofroniew, M.1    Vinters, H.B.2
  • 72
    • 0032748383 scopus 로고    scopus 로고
    • Altered glial function causes neuronal death and increases neuronal susceptibility to 1-methyl-4-phenylpyridinium- and 6-hydroxydopamine-induced toxicity in astrocytic/ventral mesencephalic co-cultures
    • Altered glial function causes neuronal death and increases neuronal susceptibility to 1-methyl-4-phenylpyridinium- and 6-hydroxydopamine-induced toxicity in astrocytic/ventral mesencephalic co-cultures. McNaught KSP, Jenner P, J of Neurochem 1999 73 2469
    • (1999) J of Neurochem , vol.73 , pp. 2469
    • McNaught, K.S.P.1    Jenner, P.2
  • 73
    • 33646241997 scopus 로고    scopus 로고
    • Purified Wnt5a protein activates or inhibits beta-catenin-TCF signaling depending on receptor context
    • 10.1371/journal.pbio.0040115 16602827
    • Purified Wnt5a protein activates or inhibits beta-catenin-TCF signaling depending on receptor context. Mikels AJ, Nusse R, PLoS Biol 2006 4 115 10.1371/journal.pbio.0040115 16602827
    • (2006) PLoS Biol , vol.4 , pp. 5115
    • Mikels, A.J.1    Nusse, R.2
  • 75
    • 33845350346 scopus 로고    scopus 로고
    • The ups and downs of Wnt signaling in prevalent neurological disorders
    • DOI 10.1038/sj.onc.1210064, PII 1210064
    • The ups and downs of Wnt signalling in prevalent neurological disorders. De Ferrari GV, Moon RT, Oncogene 2006 25 57 7545 7553 10.1038/sj.onc.1210064 17143299 (Pubitemid 44885754)
    • (2006) Oncogene , vol.25 , Issue.57 , pp. 7545-7553
    • De Ferrari, G.V.1    Moon, R.T.2
  • 76
    • 2342453952 scopus 로고    scopus 로고
    • Members of the Wnt, Fz, and Frp Gene Families Expressed in Postnatal Mouse Cerebral Cortex
    • DOI 10.1002/cne.20135
    • Members of the Wnt, Fz, and Frp gene families expressed in postnatal mouse cerebral cortex. Shimogori T, VanSant J, Paik E, Grove EA, J Comp Neurol 2004 473 4 496 510 10.1002/cne.20135 15116386 (Pubitemid 38580446)
    • (2004) Journal of Comparative Neurology , vol.473 , Issue.4 , pp. 496-510
    • Shimogori, T.1    VanSant, J.2    Paik, E.3    Grove, E.A.4
  • 80
    • 49549108896 scopus 로고    scopus 로고
    • Wnt and beyond Wnt: Multiple mechanisms control the transcriptional property of -catenin
    • 10.1016/j.cellsig.2008.04.014 18555664
    • Wnt and beyond Wnt: Multiple mechanisms control the transcriptional property of -catenin. Jin T, Fantus IG, Sun J, Cellular Signalling 2008 20 1697 1704 10.1016/j.cellsig.2008.04.014 18555664
    • (2008) Cellular Signalling , vol.20 , pp. 1697-1704
    • Jin, T.1    Fantus, I.G.2    Sun, J.3
  • 83
    • 70349745712 scopus 로고    scopus 로고
    • Expression of Wnt receptors in adult spiral ganglion neurons: Frizzled 9 localization at growth cones of regenerating neurites
    • 10.1016/j.neuroscience.2009.08.049 19716861
    • Expression of Wnt receptors in adult spiral ganglion neurons: frizzled 9 localization at growth cones of regenerating neurites. Shah SM, Kang JY, Christensen BL, Feng AS, Kollmar R, Neuroscience 2009 164 478 487 10.1016/j.neuroscience.2009.08.049 19716861
    • (2009) Neuroscience , vol.164 , pp. 478-487
    • Shah, S.M.1    Kang, J.Y.2    Christensen, B.L.3    Feng, A.S.4    Kollmar, R.5
  • 87
    • 77955514552 scopus 로고    scopus 로고
    • Gene expression profiling reveals molecular pathways associated with sporadic Parkinson's disease
    • 20513370
    • Gene expression profiling reveals molecular pathways associated with sporadic Parkinson's disease. Ohnuki T, Nakamura A, Okuyama S, Nakamura S, Brain Research 2010 1346 26 42 20513370
    • (2010) Brain Research , vol.1346 , pp. 26-42
    • Ohnuki, T.1    Nakamura, A.2    Okuyama, S.3    Nakamura, S.4
  • 88
    • 42149172511 scopus 로고    scopus 로고
    • RNA interference of LRRK2-microarray expression analysis of a Parkinson's disease key player
    • 10.1007/s10048-007-0114-0 18097693
    • RNA interference of LRRK2-microarray expression analysis of a Parkinson's disease key player. Habig K, Walter M, Poths S, Riess O, Bonin M, Neurogenetics 2008 9 83 94 10.1007/s10048-007-0114-0 18097693
    • (2008) Neurogenetics , vol.9 , pp. 83-94
    • Habig, K.1    Walter, M.2    Poths, S.3    Riess, O.4    Bonin, M.5
  • 89
    • 70349576902 scopus 로고    scopus 로고
    • Mutations in the LRRK2 Roc-COR tandem domain link Parkinson's disease to Wnt signalling pathway
    • 10.1093/hmg/ddp337 19625296
    • Mutations in the LRRK2 Roc-COR tandem domain link Parkinson's disease to Wnt signalling pathway. Sancho RM, Law BM, Harvey K, Hum Mol Genet 2009 18 3955 3968 10.1093/hmg/ddp337 19625296
    • (2009) Hum Mol Genet , vol.18 , pp. 3955-3968
    • Sancho, R.M.1    Law, B.M.2    Harvey, K.3
  • 90
    • 77951888466 scopus 로고    scopus 로고
    • Dishevelled:The hub of Wnt signalling
    • 10.1016/j.cellsig.2009.11.021 20006983
    • Dishevelled:The hub of Wnt signalling. Gao C, Cheng YG, Cell Signal 2010 22 717 727 10.1016/j.cellsig.2009.11.021 20006983
    • (2010) Cell Signal , vol.22 , pp. 717-727
    • Gao, C.1    Cheng, Y.G.2
  • 92
    • 41249103692 scopus 로고    scopus 로고
    • Catenin siRNA inhibits ischemia-induced striatal neurogenesis in adult rat brain following a transient middle cerebral artery occlusion
    • 10.1016/j.neulet.2008.02.031 18343578
    • -catenin siRNA inhibits ischemia-induced striatal neurogenesis in adult rat brain following a transient middle cerebral artery occlusion. Lei Z-NL, Zhang Lin-Mei, Sun F-Y, Neurosci Lett 2008 435 108 112 10.1016/j.neulet.2008.02. 031 18343578
    • (2008) Neurosci Lett , vol.435 , pp. 108-112
    • Lei, Z.-N.1    Zhang, L.-M.2    Sun, F.-Y.3
  • 93
    • 51649110188 scopus 로고    scopus 로고
    • Role of Dikkopf-1 (Dkk1), an antagonist of the Wnt - Catenin signaling pathway, in estrogen-induced neuroprotection and attenuation of Tau phophorylation
    • Role of Dikkopf-1 (Dkk1), an antagonist of the Wnt - catenin signaling pathway, in estrogen-induced neuroprotection and attenuation of Tau phophorylation. Zhang QG, Wang R, Khan M, Maesh V, Brann DW, J Neurosci 2009 28 8430 8441
    • (2009) J Neurosci , vol.28 , pp. 8430-8441
    • Zhang, Q.G.1    Wang, R.2    Khan, M.3    Maesh, V.4    Brann, D.W.5


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