메뉴 건너뛰기




Volumn 26, Issue 10, 2005, Pages 517-525

To be or not to be (inflamed) - Is that the question in anti-inflammatory drug therapy of neurodegenerative disorders?

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; ACETYLSALICYLIC ACID 3 (NITROXYMETHYL)PHENYL ESTER; ALPHA TOCOPHEROL; ANTIINFLAMMATORY AGENT; ANTIOXIDANT; CANNABINOID DERIVATIVE; CANNABIS; CELECOXIB; CYCLOOXYGENASE 1 INHIBITOR; CYCLOOXYGENASE 2 INHIBITOR; DOCOSAHEXAENOIC ACID; ENDOCANNABINOID; FLAVONOID; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; ICOSANOID; METAL CHELATE; MORPHINAN DERIVATIVE; NAPROXEN; NONSTEROID ANTIINFLAMMATORY AGENT; OMEGA 3 FATTY ACID; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR AGONIST; ROFECOXIB; TETRACYCLINE DERIVATIVE; VALDECOXIB;

EID: 25144468525     PISSN: 01656147     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tips.2005.08.007     Document Type: Review
Times cited : (163)

References (75)
  • 1
    • 5444238963 scopus 로고    scopus 로고
    • The fires within
    • C. Gorman, and A. Park The fires within Time 1 2004 45 51
    • (2004) Time , vol.1 , pp. 45-51
    • Gorman, C.1    Park, A.2
  • 2
    • 0041522790 scopus 로고    scopus 로고
    • Non steroidal anti-inflammatory drugs protect against Parkinson neurodegeneration: Can an NSAID a day keep Parkinson disease away?
    • M. Schiess Non steroidal anti-inflammatory drugs protect against Parkinson neurodegeneration: can an NSAID a day keep Parkinson disease away? Arch. Neurol. 60 2003 1043 1044
    • (2003) Arch. Neurol. , vol.60 , pp. 1043-1044
    • Schiess, M.1
  • 3
    • 17844382673 scopus 로고    scopus 로고
    • Innate (inherent) control of brain infection, brain inflammation and brain repair: The role of microglia, astrocytes, "protective" glial stem cells and stromal ependymal cells
    • M. Hauwel Innate (inherent) control of brain infection, brain inflammation and brain repair: the role of microglia, astrocytes, "protective" glial stem cells and stromal ependymal cells Brain Res. Brain Res. Rev. 48 2005 220 233
    • (2005) Brain Res. Brain Res. Rev. , vol.48 , pp. 220-233
    • Hauwel, M.1
  • 4
    • 1542317072 scopus 로고    scopus 로고
    • Reactive astrocytes protect tissue and preserve function after spinal cord injury
    • J.R. Faulkner Reactive astrocytes protect tissue and preserve function after spinal cord injury J. Neurosci. 24 2004 2143 2155
    • (2004) J. Neurosci. , vol.24 , pp. 2143-2155
    • Faulkner, J.R.1
  • 5
    • 17844371932 scopus 로고    scopus 로고
    • New insight into COX-2 biology and inhibition
    • P. Patrignani New insight into COX-2 biology and inhibition Brain Res. Brain Res. Rev. 48 2005 352 359
    • (2005) Brain Res. Brain Res. Rev. , vol.48 , pp. 352-359
    • Patrignani, P.1
  • 6
    • 0034944344 scopus 로고    scopus 로고
    • Modulation of cyclooxygenase-2 and brain reactive astrogliosis by purinergic P2 receptors
    • R. Brambilla, and M.P. Abbracchio Modulation of cyclooxygenase-2 and brain reactive astrogliosis by purinergic P2 receptors Ann. New York Acad. Sci. 939 2001 54 62
    • (2001) Ann. New York Acad. Sci. , vol.939 , pp. 54-62
    • Brambilla, R.1    Abbracchio, M.P.2
  • 7
    • 77954329712 scopus 로고    scopus 로고
    • Glia-neuron crosstalk in neuroinflammation, neurodegeneration and neuroprotection
    • B. Marchetti Glia-neuron crosstalk in neuroinflammation, neurodegeneration and neuroprotection Brain Res. Brain Res. Rev. 48 2005 129 408
    • (2005) Brain Res. Brain Res. Rev. , vol.48 , pp. 129-408
    • Marchetti, B.1
  • 8
    • 2642542373 scopus 로고    scopus 로고
    • Pro-regenerative properties of cytokine-activated astrocytes
    • C.M. Liberto Pro-regenerative properties of cytokine-activated astrocytes J. Neurochem. 89 2004 1092 1100
    • (2004) J. Neurochem. , vol.89 , pp. 1092-1100
    • Liberto, C.M.1
  • 9
    • 0345189366 scopus 로고    scopus 로고
    • Inflammatory blockade restores adult hippocampal neurogenesis
    • M.L. Monje Inflammatory blockade restores adult hippocampal neurogenesis Science 302 2003 1760 1765
    • (2003) Science , vol.302 , pp. 1760-1765
    • Monje, M.L.1
  • 10
    • 17844404517 scopus 로고    scopus 로고
    • Microglia and neuroprotection: Implication for Alzheimer's disease
    • W.J.S. Streit Microglia and neuroprotection: implication for Alzheimer's disease Brain Res. Brain Res. Rev. 48 2005 234 239
    • (2005) Brain Res. Brain Res. Rev. , vol.48 , pp. 234-239
    • Streit, W.J.S.1
  • 11
    • 20044376483 scopus 로고    scopus 로고
    • Experimental autoimmune encephalomyelitis repressed by microglial paralysis
    • F.L. Heppner Experimental autoimmune encephalomyelitis repressed by microglial paralysis Nat. Med. 11 2005 146 152
    • (2005) Nat. Med. , vol.11 , pp. 146-152
    • Heppner, F.L.1
  • 12
    • 20444422539 scopus 로고    scopus 로고
    • Protective autoimmunity in inflammatory and non inflammatory neurodegenerative diseases
    • M. Schwartz, and J. Kipnis Protective autoimmunity in inflammatory and non inflammatory neurodegenerative diseases J. Neurol. Sci. 233 2005 163 166
    • (2005) J. Neurol. Sci. , vol.233 , pp. 163-166
    • Schwartz, M.1    Kipnis, J.2
  • 13
    • 0037379324 scopus 로고    scopus 로고
    • Genetic and environmental factors in the cause of Parkinson's disease
    • T.T. Warner, and A.H.V. Schapira Genetic and environmental factors in the cause of Parkinson's disease Ann. Neurol. 53 2003 S16 S25
    • (2003) Ann. Neurol. , vol.53
    • Warner, T.T.1    Schapira, A.H.V.2
  • 14
    • 4644234931 scopus 로고    scopus 로고
    • Association between the interleukin-1alpha gene and Alzheimer's disease: A meta-analysis
    • I. Rainero Association between the interleukin-1alpha gene and Alzheimer's disease: a meta-analysis Neurobiol. Aging 25 2004 1293 1298
    • (2004) Neurobiol. Aging , vol.25 , pp. 1293-1298
    • Rainero, I.1
  • 15
    • 12244299912 scopus 로고    scopus 로고
    • Association between Parkinson's disease and polymorphisms in the nNOS and iNOS genes in a community-based case-control study
    • C. Levecque Association between Parkinson's disease and polymorphisms in the nNOS and iNOS genes in a community-based case-control study Hum. Mol. Genet. 12 2003 79 86
    • (2003) Hum. Mol. Genet. , vol.12 , pp. 79-86
    • Levecque, C.1
  • 16
    • 0000237112 scopus 로고    scopus 로고
    • The hypothalamic-pituitary-gonadal axis and the immune system
    • 3rd Edn, Raven Press
    • Marchetti, B. et al. (2001) The hypothalamic-pituitary-gonadal axis and the immune system. In PsychoNeuro-Immunology (Vol. 1, 3rd Edn), pp. 363-387, Raven Press
    • (2001) PsychoNeuro-Immunology , vol.1 , pp. 363-387
    • Marchetti, B.1
  • 17
    • 3042833447 scopus 로고    scopus 로고
    • Overview if the actions of glucocorticoids on the immune response: Good model to characterize new pathways of immunosuppression for new treatments
    • D. Franchimont Overview if the actions of glucocorticoids on the immune response: good model to characterize new pathways of immunosuppression for new treatments Ann. New York Acad. Sci. 1024 2004 124 137
    • (2004) Ann. New York Acad. Sci. , vol.1024 , pp. 124-137
    • Franchimont, D.1
  • 18
    • 17844407395 scopus 로고    scopus 로고
    • Glia-neuron crosstalk in the neuroprotective mechanisms of sex steroid hormones
    • D. Garcia-Ovejero Glia-neuron crosstalk in the neuroprotective mechanisms of sex steroid hormones Brain Res. Brain Res. Rev. 48 2005 273 286
    • (2005) Brain Res. Brain Res. Rev. , vol.48 , pp. 273-286
    • Garcia-Ovejero, D.1
  • 19
    • 1342332143 scopus 로고    scopus 로고
    • Glucocorticoid receptor deficiency increases vulnerability of the nigrostriatal dopaminergic system: Critical role of glial nitric oxide
    • M.C. Morale Glucocorticoid receptor deficiency increases vulnerability of the nigrostriatal dopaminergic system: critical role of glial nitric oxide FASEB J. 18 2003 164 166
    • (2003) FASEB J. , vol.18 , pp. 164-166
    • Morale, M.C.1
  • 20
    • 20244369883 scopus 로고    scopus 로고
    • Glucocorticoid receptor-nitric oxide crosstalk and vulnerability to experimental parkinsonism: Pivotal role for glia-neuron interactions
    • B. Marchetti Glucocorticoid receptor-nitric oxide crosstalk and vulnerability to experimental parkinsonism: pivotal role for glia-neuron interactions Brain Res. Brain Res. Rev. 48 2005 302 321
    • (2005) Brain Res. Brain Res. Rev. , vol.48 , pp. 302-321
    • Marchetti, B.1
  • 21
    • 85059205313 scopus 로고    scopus 로고
    • Estrogen, neuroinflammation and neuroprotection in Parkinson's disease: Glia dictates resistance versus vulnerability to neurodegeneration
    • (in press)
    • Morale, M.C. et al. Estrogen, neuroinflammation and neuroprotection in Parkinson's disease: glia dictates resistance versus vulnerability to neurodegeneration. Neuroscience (in press)
    • Neuroscience
    • Morale, M.C.1
  • 22
    • 19944431987 scopus 로고    scopus 로고
    • Interaction of polymorphisms in the genes encoding intereukin-6 and estrogen receptor beta on the susceptibility to Parkinson's disease
    • A. Hakansson Interaction of polymorphisms in the genes encoding intereukin-6 and estrogen receptor beta on the susceptibility to Parkinson's disease Am. J. Med. Genet. B Neuropsychiatr. For. Genet. 133 2005 88 92
    • (2005) Am. J. Med. Genet. B Neuropsychiatr. For. Genet. , vol.133 , pp. 88-92
    • Hakansson, A.1
  • 23
    • 0041922555 scopus 로고    scopus 로고
    • Estrogen receptor-alpha mediates the brain antiinflammatory activity of estradiol
    • E. Vegeto Estrogen receptor-alpha mediates the brain antiinflammatory activity of estradiol Proc. Natl. Acad. Sci. U. S. A. 100 2003 9614 9619
    • (2003) Proc. Natl. Acad. Sci. U. S. A. , vol.100 , pp. 9614-9619
    • Vegeto, E.1
  • 24
    • 0035659977 scopus 로고    scopus 로고
    • Stress, the immune system and vulnerability to degenerative disorders of the central nervous system in transgenic mice expressing glucocorticoid receptor antisense RNA
    • B. Marchetti Stress, the immune system and vulnerability to degenerative disorders of the central nervous system in transgenic mice expressing glucocorticoid receptor antisense RNA Brain Res. Brain Res. Rev. 37 2001 259 272
    • (2001) Brain Res. Brain Res. Rev. , vol.37 , pp. 259-272
    • Marchetti, B.1
  • 25
    • 0043162103 scopus 로고    scopus 로고
    • Novel anti-inflammatory therapy for Parkinson's disease
    • H.M. Gao Novel anti-inflammatory therapy for Parkinson's disease Trends Pharmacol. Sci. 24 2003 395 401
    • (2003) Trends Pharmacol. Sci. , vol.24 , pp. 395-401
    • Gao, H.M.1
  • 26
    • 1342323484 scopus 로고    scopus 로고
    • Combined toxicity of prenatal bacterial endotoxin exposure and postnatal 6-hydroxydopamine in the adult rat midbrain
    • Z.D. Ling Combined toxicity of prenatal bacterial endotoxin exposure and postnatal 6-hydroxydopamine in the adult rat midbrain Neuroscience 124 2004 619 628
    • (2004) Neuroscience , vol.124 , pp. 619-628
    • Ling, Z.D.1
  • 27
    • 2342584710 scopus 로고    scopus 로고
    • Environmental enrichment reverses learning impairment in the Morris water maze after focal cerebral ischemia in rats
    • P. Dahlqvist Environmental enrichment reverses learning impairment in the Morris water maze after focal cerebral ischemia in rats Eur. J. Neurosci. 19 2004 2288 2298
    • (2004) Eur. J. Neurosci. , vol.19 , pp. 2288-2298
    • Dahlqvist, P.1
  • 28
    • 1542286877 scopus 로고    scopus 로고
    • Environmental enrichment rescues protein deficits in a mouse model of Huntington's disease, indicating a possible disease mechanism
    • T.L. Spires Environmental enrichment rescues protein deficits in a mouse model of Huntington's disease, indicating a possible disease mechanism J. Neurosci. 24 2004 2270 2276
    • (2004) J. Neurosci. , vol.24 , pp. 2270-2276
    • Spires, T.L.1
  • 29
    • 1642422752 scopus 로고    scopus 로고
    • Enriched environment, nitric oxide production and synaptic plasticity prevent the aging-dependent impairment of spatial cognition
    • S.L. Arnaiz Enriched environment, nitric oxide production and synaptic plasticity prevent the aging-dependent impairment of spatial cognition Mol. Aspects Med. 25 2004 91 101
    • (2004) Mol. Aspects Med. , vol.25 , pp. 91-101
    • Arnaiz, S.L.1
  • 30
    • 0036771289 scopus 로고    scopus 로고
    • Inflammatory mechanisms, arteriosclerosis and ischemic stroke: Clinical data and perspectives
    • L.C. Alvaro-Gonzalez Inflammatory mechanisms, arteriosclerosis and ischemic stroke: clinical data and perspectives Rev. Neurol. 35 2002 452 462
    • (2002) Rev. Neurol. , vol.35 , pp. 452-462
    • Alvaro-Gonzalez, L.C.1
  • 31
    • 0036897540 scopus 로고    scopus 로고
    • Inflammation and infection in clinical stroke
    • H.C. Emsley, and P.J. Tyrrell Inflammation and infection in clinical stroke J. Cereb. Blood Flow Metab. 22 2002 1399 1419
    • (2002) J. Cereb. Blood Flow Metab. , vol.22 , pp. 1399-1419
    • Emsley, H.C.1    Tyrrell, P.J.2
  • 32
    • 0346366987 scopus 로고    scopus 로고
    • Nasal vaccination with myelin oligodendrocyte glycoprotein reduces stroke size by inducing IL-10-producing CD4+ T cells
    • D. Frenkel Nasal vaccination with myelin oligodendrocyte glycoprotein reduces stroke size by inducing IL-10-producing CD4+ T cells J. Immunol. 171 2003 6549 6555
    • (2003) J. Immunol. , vol.171 , pp. 6549-6555
    • Frenkel, D.1
  • 33
    • 16644395324 scopus 로고    scopus 로고
    • Cholesterol-independent effects of statins and new therapeutic targets: Ischemic stroke and dementia
    • T. Miida Cholesterol-independent effects of statins and new therapeutic targets: ischemic stroke and dementia J. Atheroscler. Thromb. 11 2004 253 264
    • (2004) J. Atheroscler. Thromb. , vol.11 , pp. 253-264
    • Miida, T.1
  • 34
    • 0037378912 scopus 로고    scopus 로고
    • Neuroprotection for Parkinson's disease: Prospects and promises
    • C.W. Olanov Neuroprotection for Parkinson's disease: prospects and promises Ann. Neurol. 53 Suppl. 3 2003 S1 S2
    • (2003) Ann. Neurol. , vol.53 , Issue.3 SUPPL.
    • Olanov, C.W.1
  • 35
    • 1942454250 scopus 로고    scopus 로고
    • Inflammation and neurodegeneration in Parkinson's disease
    • P.L. McGeer, and E.G. McGeer Inflammation and neurodegeneration in Parkinson's disease Parkinsonism Relat. Disord. 10 Suppl. 1 2004 S3 S7
    • (2004) Parkinsonism Relat. Disord. , vol.10 , Issue.1 SUPPL.
    • McGeer, P.L.1    McGeer, E.G.2
  • 36
    • 0842277733 scopus 로고    scopus 로고
    • Inflammation and dopaminergic neuronal loss in Parkinson' disease: A complex matter
    • A. Hartmann Inflammation and dopaminergic neuronal loss in Parkinson' disease: a complex matter Exp. Neurol. 184 2003 561 564
    • (2003) Exp. Neurol. , vol.184 , pp. 561-564
    • Hartmann, A.1
  • 37
    • 0038389514 scopus 로고    scopus 로고
    • COX-2 and neurodegeneration in Parkinson's disease
    • P. Teismann COX-2 and neurodegeneration in Parkinson's disease Ann. New York Acad. Sci. 991 2003 272 277
    • (2003) Ann. New York Acad. Sci. , vol.991 , pp. 272-277
    • Teismann, P.1
  • 38
    • 0036522967 scopus 로고    scopus 로고
    • Blockade of microglia activation is neuroprotective in the MPTP mouse model of Parkinson's disease
    • D.C. Wu Blockade of microglia activation is neuroprotective in the MPTP mouse model of Parkinson's disease J. Neurosci. 22 2002 1763 1771
    • (2002) J. Neurosci. , vol.22 , pp. 1763-1771
    • Wu, D.C.1
  • 39
    • 0041653249 scopus 로고    scopus 로고
    • Nonsteroidal anti-inflammatory drugs and the risk of Parkinson's disease
    • H. Chen Nonsteroidal anti-inflammatory drugs and the risk of Parkinson's disease Arch. Neurol. 60 2003 1059 1064
    • (2003) Arch. Neurol. , vol.60 , pp. 1059-1064
    • Chen, H.1
  • 40
    • 3042592589 scopus 로고    scopus 로고
    • Therapeutic immunization protects dopaminergic neurons in a mouse model of Parkinson's disease
    • E.J. Benner Therapeutic immunization protects dopaminergic neurons in a mouse model of Parkinson's disease Proc. Natl. Acad. Sci. U. S. A. 101 2004 9435 9440
    • (2004) Proc. Natl. Acad. Sci. U. S. A. , vol.101 , pp. 9435-9440
    • Benner, E.J.1
  • 41
    • 0347087323 scopus 로고    scopus 로고
    • Protection by pioglitazone in the MPTP model of Parkinson's disease correlates with I kappa B alpha induction and block of NF kappa B and iNOS activation
    • T. Dehmer Protection by pioglitazone in the MPTP model of Parkinson's disease correlates with I kappa B alpha induction and block of NF kappa B and iNOS activation J. Neurochem. 88 2004 494 501
    • (2004) J. Neurochem. , vol.88 , pp. 494-501
    • Dehmer, T.1
  • 42
    • 20444482731 scopus 로고    scopus 로고
    • Patohogenesis of multiple sclerosis
    • A. Prat, and J. Antel Patohogenesis of multiple sclerosis Curr. Opin. Neurol. 18 2005 225 230
    • (2005) Curr. Opin. Neurol. , vol.18 , pp. 225-230
    • Prat, A.1    Antel, J.2
  • 43
    • 17844392320 scopus 로고    scopus 로고
    • Cytokine and chemokine inter-regulation in the inflammed or injured CNS
    • T. Owens Cytokine and chemokine inter-regulation in the inflammed or injured CNS Brain Res. Brain Res. Rev. 48 2005 178 184
    • (2005) Brain Res. Brain Res. Rev. , vol.48 , pp. 178-184
    • Owens, T.1
  • 44
    • 17844381010 scopus 로고    scopus 로고
    • Macrophages and neurodegeneration
    • J.J. Hendriks Macrophages and neurodegeneration Brain Res. Brain Res. Rev. 48 2005 185 195
    • (2005) Brain Res. Brain Res. Rev. , vol.48 , pp. 185-195
    • Hendriks, J.J.1
  • 45
    • 0033400628 scopus 로고    scopus 로고
    • Our shifting understanding of the role of nitric oxide in autoimmune encephalomyelitis: A review
    • D.O. Willenborg Our shifting understanding of the role of nitric oxide in autoimmune encephalomyelitis: a review J. Neuroimmunol. 100 1999 21 35
    • (1999) J. Neuroimmunol. , vol.100 , pp. 21-35
    • Willenborg, D.O.1
  • 46
    • 17844395680 scopus 로고    scopus 로고
    • Hormone regulation of microglial cell activation: Relevance to multiple sclerosis
    • P. Drew Hormone regulation of microglial cell activation: relevance to multiple sclerosis Brain Res. Brain Res. Rev. 48 2005 322 327
    • (2005) Brain Res. Brain Res. Rev. , vol.48 , pp. 322-327
    • Drew, P.1
  • 47
    • 0036604085 scopus 로고    scopus 로고
    • Exposure to a dysfunctional glucocorticoid receptor from early embryonic life programs the resistance to experimental allergic encephalomyelitis via nitric oxide-induced immunosuppression
    • B. Marchetti Exposure to a dysfunctional glucocorticoid receptor from early embryonic life programs the resistance to experimental allergic encephalomyelitis via nitric oxide-induced immunosuppression J. Immunol. 168 2002 5848 5859
    • (2002) J. Immunol. , vol.168 , pp. 5848-5859
    • Marchetti, B.1
  • 48
    • 11144357288 scopus 로고    scopus 로고
    • Peroxisome prolferator activated receptor alpha agonists as therapy for autoimmune diseases
    • A.E. Lovett-Racke Peroxisome prolferator activated receptor alpha agonists as therapy for autoimmune diseases J. Immunol. 172 2004 5790 5798
    • (2004) J. Immunol. , vol.172 , pp. 5790-5798
    • Lovett-Racke, A.E.1
  • 49
    • 9144253117 scopus 로고    scopus 로고
    • Sodium salicylate-induced amelioration of experimental allergic encephalomyelitis in Lewis rats is associated with suppression of inducible nitric oxide synthase and cyclooxygenases
    • C. Moon Sodium salicylate-induced amelioration of experimental allergic encephalomyelitis in Lewis rats is associated with suppression of inducible nitric oxide synthase and cyclooxygenases Neurosci. Lett. 356 2004 123 126
    • (2004) Neurosci. Lett. , vol.356 , pp. 123-126
    • Moon, C.1
  • 50
    • 11144353904 scopus 로고    scopus 로고
    • A nitric oxide derivative of flurbiprofen inhibits experimental autoimmune encephalomyelitis
    • R. Furlan A nitric oxide derivative of flurbiprofen inhibits experimental autoimmune encephalomyelitis J. Neuroimmunol. 150 2004 10 19
    • (2004) J. Neuroimmunol. , vol.150 , pp. 10-19
    • Furlan, R.1
  • 51
    • 1842611884 scopus 로고    scopus 로고
    • Cannabinoids and neuroinflammation
    • L. Walter, and N. Stella Cannabinoids and neuroinflammation Br. J. Pharmacol. 141 2004 775 785
    • (2004) Br. J. Pharmacol. , vol.141 , pp. 775-785
    • Walter, L.1    Stella, N.2
  • 52
    • 0344987883 scopus 로고    scopus 로고
    • Immunomodulation in multiple sclerosis: From immunosuppression to neuroprotection
    • O. Neuhaus Immunomodulation in multiple sclerosis: from immunosuppression to neuroprotection Trends Pharmacol. Sci. 24 2003 131 138
    • (2003) Trends Pharmacol. Sci. , vol.24 , pp. 131-138
    • Neuhaus, O.1
  • 53
    • 2442532533 scopus 로고    scopus 로고
    • How the brain repairs itself: New therapeutic strategies in inflammatory and degenerative CNS disorders
    • G. Martino How the brain repairs itself: new therapeutic strategies in inflammatory and degenerative CNS disorders Lancet Neurol. 3 2004 372 378
    • (2004) Lancet Neurol. , vol.3 , pp. 372-378
    • Martino, G.1
  • 54
    • 22444450988 scopus 로고    scopus 로고
    • Neurosphere-derived multipotent precursors promote neuroprotection by an immunomodulatory mechanism
    • S. Pluchino Neurosphere-derived multipotent precursors promote neuroprotection by an immunomodulatory mechanism Nature 436 2005 266 271
    • (2005) Nature , vol.436 , pp. 266-271
    • Pluchino, S.1
  • 55
    • 0029811901 scopus 로고    scopus 로고
    • Arthritis and anti-inflammatory agents as possible protective factors for Alzheimer's disease: A review of 17 epidemiologic studies
    • P.L. McGeer Arthritis and anti-inflammatory agents as possible protective factors for Alzheimer's disease: a review of 17 epidemiologic studies Neurology 47 1996 425 432
    • (1996) Neurology , vol.47 , pp. 425-432
    • McGeer, P.L.1
  • 56
    • 0037167542 scopus 로고    scopus 로고
    • Reduced incidence of AD with NSAID but not H2 receptor antagonists: The Cache County Study
    • P.P. Zandi Reduced incidence of AD with NSAID but not H2 receptor antagonists: the Cache County Study Neurology 59 2002 880 886
    • (2002) Neurology , vol.59 , pp. 880-886
    • Zandi, P.P.1
  • 57
    • 1542283611 scopus 로고    scopus 로고
    • Neuroinflammatory perspectives on the two faces of Alzheimer's disease
    • P. Eikelenboom, and W.A. van Gool Neuroinflammatory perspectives on the two faces of Alzheimer's disease J. Neural Transm. 111 2004 281 294
    • (2004) J. Neural Transm. , vol.111 , pp. 281-294
    • Eikelenboom, P.1    Van Gool, W.A.2
  • 58
    • 0041628645 scopus 로고    scopus 로고
    • Cyclo-oxygenase inhibitors and Alzheimer's: Are we well ADAPTed?
    • G.M. Pasinetti, and P.N. Pompl Cyclo-oxygenase inhibitors and Alzheimer's: are we well ADAPTed? Lancet Neurol. 1 2002 403 404
    • (2002) Lancet Neurol. , vol.1 , pp. 403-404
    • Pasinetti, G.M.1    Pompl, P.N.2
  • 59
    • 3442893295 scopus 로고    scopus 로고
    • Cytokines in neuroinflammation and Alzheimer's disease
    • M. Cacquevel Cytokines in neuroinflammation and Alzheimer's disease Curr. Drug Targets 5 2004 529 534
    • (2004) Curr. Drug Targets , vol.5 , pp. 529-534
    • Cacquevel, M.1
  • 60
    • 14944372848 scopus 로고    scopus 로고
    • NSAID and antioxidant prevention of Alzheimer's Disease: Lessons from in vitro and animal models
    • G.M. Cole NSAID and antioxidant prevention of Alzheimer's Disease: lessons from in vitro and animal models Ann. New York Acad. Sci. 1035 2004 68 84
    • (2004) Ann. New York Acad. Sci. , vol.1035 , pp. 68-84
    • Cole, G.M.1
  • 61
    • 0042347804 scopus 로고    scopus 로고
    • Anti-inflammatory therapy in Alzheimer's disease: Is hope still alive?
    • W.A. van Gool Anti-inflammatory therapy in Alzheimer's disease: is hope still alive? J. Neurol. 250 2003 788 792
    • (2003) J. Neurol. , vol.250 , pp. 788-792
    • Van Gool, W.A.1
  • 62
    • 0037638809 scopus 로고    scopus 로고
    • Effects of rofecoxib or naproxen vs placebo on Alzheimer disease progression: A randomized controlled trial
    • P.S. Aisen Effects of rofecoxib or naproxen vs placebo on Alzheimer disease progression: a randomized controlled trial J. Am. Med. Assoc. 289 2003 2819 2826
    • (2003) J. Am. Med. Assoc. , vol.289 , pp. 2819-2826
    • Aisen, P.S.1
  • 63
    • 17844385791 scopus 로고    scopus 로고
    • Interactions between Alzheimer's disease and cerebral ischemia - Focus on inflammation
    • M. Koistinaho, and J. Koistinaho Interactions between Alzheimer's disease and cerebral ischemia - focus on inflammation Brain Res. Brain Res. Rev. 48 2005 240 250
    • (2005) Brain Res. Brain Res. Rev. , vol.48 , pp. 240-250
    • Koistinaho, M.1    Koistinaho, J.2
  • 64
    • 17844406615 scopus 로고    scopus 로고
    • Mechanism of neuroprotective action of the antiParkinson drug rasagiline and its derivatives
    • S. Mandel Mechanism of neuroprotective action of the antiParkinson drug rasagiline and its derivatives Brain Res. Brain Res. Rev. 48 2005 379 387
    • (2005) Brain Res. Brain Res. Rev. , vol.48 , pp. 379-387
    • Mandel, S.1
  • 65
    • 3242710339 scopus 로고    scopus 로고
    • The influence of systemic inflammation on inflammation in the brain: Implications for chronic neurodegenerative disease
    • V.H. Perry The influence of systemic inflammation on inflammation in the brain: implications for chronic neurodegenerative disease Brain Behav. Immun. 18 2004 407 413
    • (2004) Brain Behav. Immun. , vol.18 , pp. 407-413
    • Perry, V.H.1
  • 66
    • 2342623445 scopus 로고    scopus 로고
    • Inflammatory mediators in the elderly
    • K.S. Krabbe Inflammatory mediators in the elderly Exp. Gerontol. 39 2004 687 699
    • (2004) Exp. Gerontol. , vol.39 , pp. 687-699
    • Krabbe, K.S.1
  • 67
    • 3042667647 scopus 로고    scopus 로고
    • Catechin polyphenols, neurodegeneration and neuroprotection in neurodegenerative diseases
    • S. Mandel, and M.B.H. Youdim Catechin polyphenols, neurodegeneration and neuroprotection in neurodegenerative diseases Free Radic. Biol. Med. 37 2004 304 317
    • (2004) Free Radic. Biol. Med. , vol.37 , pp. 304-317
    • Mandel, S.1    Youdim, M.B.H.2
  • 68
    • 14044273642 scopus 로고    scopus 로고
    • Biomarkers for apoptosis in Alzheimer's disease
    • M. Ankarcrona, and B. Winblad Biomarkers for apoptosis in Alzheimer's disease Int. J. Geriatr. Psychiatry 20 2005 101 105
    • (2005) Int. J. Geriatr. Psychiatry , vol.20 , pp. 101-105
    • Ankarcrona, M.1    Winblad, B.2
  • 69
    • 0036850086 scopus 로고    scopus 로고
    • Visualising microglia activation in vivo
    • R.B. Banati Visualising microglia activation in vivo Glia 40 2002 206 217
    • (2002) Glia , vol.40 , pp. 206-217
    • Banati, R.B.1
  • 70
    • 17844408665 scopus 로고    scopus 로고
    • Ligands for peripheral benzodiazepine binding sites in glial cells
    • M. Kassiou Ligands for peripheral benzodiazepine binding sites in glial cells Brain Res. Brain Res. Rev. 48 2005 207 210
    • (2005) Brain Res. Brain Res. Rev. , vol.48 , pp. 207-210
    • Kassiou, M.1
  • 71
    • 17844407142 scopus 로고    scopus 로고
    • From proteonomic to biomarker discovery in Alzheimer's disease
    • L. Ho From proteonomic to biomarker discovery in Alzheimer's disease Brain Res. Brain Res. Rev. 48 2005 360 369
    • (2005) Brain Res. Brain Res. Rev. , vol.48 , pp. 360-369
    • Ho, L.1
  • 72
    • 9644304486 scopus 로고    scopus 로고
    • Cytokine genes and disease susceptibility
    • W.E. Ollier Cytokine genes and disease susceptibility Cytokine 28 2004 174 178
    • (2004) Cytokine , vol.28 , pp. 174-178
    • Ollier, W.E.1
  • 73
    • 2442553712 scopus 로고    scopus 로고
    • High frequency of TNF alleles and -376A in individuals from northern Sardinia
    • S.A. Wirz High frequency of TNF alleles and -376A in individuals from northern Sardinia Cytokine 26 2004 149 154
    • (2004) Cytokine , vol.26 , pp. 149-154
    • Wirz, S.A.1
  • 74
    • 2942741011 scopus 로고    scopus 로고
    • A polymorphism of the interleukn-1 beta gene at position +3953 influences the progression and neuro-pathological hallmarks of Alzheimer's disease
    • F. Licastro A polymorphism of the interleukn-1 beta gene at position +3953 influences the progression and neuro-pathological hallmarks of Alzheimer's disease Neurobiol. Aging 25 2004 1017 1022
    • (2004) Neurobiol. Aging , vol.25 , pp. 1017-1022
    • Licastro, F.1
  • 75
    • 13444293097 scopus 로고    scopus 로고
    • Upregulation of A2A adenosine receptor expression by TNF-alpha in PBMC of patients with CHF: A regulatory mechanism of inflammation
    • L. Capecchi Upregulation of A2A adenosine receptor expression by TNF-alpha in PBMC of patients with CHF: a regulatory mechanism of inflammation J. Card. Fail. 11 2005 67 73
    • (2005) J. Card. Fail. , vol.11 , pp. 67-73
    • Capecchi, L.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.