Human neuromelanin: An endogenous microglial activator for dopaminergic neuron death

Frontiers in Bioscience - Elite

Volumn 5 E, Issue 1, 2013, Pages 1-11

  Zhang, Wei ^a   Zecca, Luigi ^b   Wilson, Belinda ^c   Ren, Hong Wei ^d   Wang, Yong Jun ^a   Wang, Xiao Min ^e   Hong, Jau Shyong ^c  

^a CAPITAL MEDICAL UNIVERSITY   (China)

^b INSTITUTE OF BIOMEDICAL TECHNOLOGIES   (Italy)

^c NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^d PEKING UNIVERSITY   (China)

^e CAPITAL MEDICAL UNIVERSITY   (China)

Author keywords

Activation; Dopaminergic neuron; Human neuromelanin; Microglia; Neurodegeneration; Parkinson's disease; Substantia nigra pars compacta

Indexed keywords

NEUROMELANIN; NITRIC OXIDE; PROSTAGLANDIN E2; TUMOR NECROSIS FACTOR ALPHA; DOPAMINE; MELANIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL CULTURE; CELL DEATH; CONTROLLED STUDY; DOPAMINERGIC NERVE CELL; FEMALE; GLIOSIS; IMMUNOCYTOCHEMISTRY; MACROGLIA; MICROGLIA; NEUROTOXICITY; NONHUMAN; RAT; SUBSTANTIA NIGRA; ANALYSIS OF VARIANCE; ANIMAL; DENDRITE; DRUG EFFECT; HUMAN; IMMUNOHISTOCHEMISTRY; METABOLISM; PARKINSON DISEASE; PATHOPHYSIOLOGY; PHYSIOLOGY; PREGNANCY;

ANALYSIS OF VARIANCE; ANIMALS; CELL DEATH; CELLS, CULTURED; DENDRITES; DOPAMINE; DOPAMINERGIC NEURONS; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; MELANINS; MICROGLIA; NITRIC OXIDE; PARKINSON DISEASE; PREGNANCY; RATS; SUBSTANTIA NIGRA; TUMOR NECROSIS FACTOR-ALPHA;

MLCS; MLOWN;

EID: 84878510699     PISSN: 19450494     EISSN: 19450508     Source Type: Journal    
DOI: 10.2741/e591     Document Type: Article

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