메뉴 건너뛰기




Volumn 94, Issue 2, 2014, Pages 419-459

Structure and function of tmem16 proteins (anoctamins)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM ION; CALMODULIN; MEMBRANE PROTEIN; PEPTIDES AND PROTEINS; PHOSPHATIDYLSERINE; POTASSIUM CHANNEL; PROTEIN TMEM16; UNCLASSIFIED DRUG;

EID: 84900406113     PISSN: 00319333     EISSN: 15221210     Source Type: Journal    
DOI: 10.1152/physrev.00039.2011     Document Type: Article
Times cited : (408)

References (268)
  • 2
    • 84880756263 scopus 로고    scopus 로고
    • Putative pore-loops of TMEM16/ anoctamin channels affect channel density in cell membranes
    • Adomaviciene A, Smith KJ, Garnett H, Tammaro P. Putative pore-loops of TMEM16/ anoctamin channels affect channel density in cell membranes. J Physiol 591: 3487-3505, 2013.
    • (2013) J Physiol , vol.591 , pp. 3487-3505
    • Adomaviciene, A.1    Smith, K.J.2    Garnett, H.3    Tammaro, P.4
  • 4
    • 70350038016 scopus 로고    scopus 로고
    • Mapping the human membrane proteome: A majority of the humanmembrane proteins can be classified according to function and evolutionary origin
    • Almén MS, Nordström KJV, Fredriksson R, Schiöth HB. Mapping the human membrane proteome: a majority of the humanmembrane proteins can be classified according to function and evolutionary origin. BMC Biol 7: 50, 2009.
    • (2009) BMC Biol , vol.7 , pp. 50
    • Almén, M.S.1    Nordström, K.J.V.2    Fredriksson, R.3    Schiöth, H.B.4
  • 5
    • 0025871551 scopus 로고
    • Calcium and cAMP activate different chloride channels in the apical membrane of normal and cystic fibrosis epithelia
    • Anderson MP, Welsh MJ. Calcium and cAMP activate different chloride channels in the apical membrane of normal and cystic fibrosis epithelia. Proc Natl Acad Sci USA 88: 6003-6007, 1991.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 6003-6007
    • Anderson, M.P.1    Welsh, M.J.2
  • 7
    • 0029941550 scopus 로고    scopus 로고
    • Activation of calcium-dependent chloride channels in rat parotid acinar cells
    • Arreola J, Melvin JE, Begenisich T. Activation of calcium-dependent chloride channels in rat parotid acinar cells. J Physiol 108: 35-47, 1996.
    • (1996) J Physiol , vol.108 , pp. 35-47
    • Arreola, J.1    Melvin, J.E.2    Begenisich, T.3
  • 9
    • 77955983967 scopus 로고    scopus 로고
    • ANO1 amplification and expression in HNSCC with a high propensity for future distant metastasis and its functions in HNSCC cell lines
    • Ayoub C, Wasylyk C, Li Y, Thomas E, Marisa L, Robé A, Roux M, Abecassis J, de Reyniès A, Wasylyk B. ANO1 amplification and expression in HNSCC with a high propensity for future distant metastasis and its functions in HNSCC cell lines. Br J Cancer 103: 715-726, 2010.
    • (2010) Br J Cancer , vol.103 , pp. 715-726
    • Ayoub, C.1    Wasylyk, C.2    Li, Y.3    Thomas, E.4    Marisa, L.5    Robé, A.6    Roux, M.7    Abecassis, J.8    de Reyniès, A.9    Wasylyk, B.10
  • 13
    • 0026705338 scopus 로고
    • Contribution of Ca and Ca-activated Cl channels to regenerative depolarization and membrane bistability of cone photoreceptors
    • Barnes S, Deschênes MC. Contribution of Ca and Ca-activated Cl channels to regenerative depolarization and membrane bistability of cone photoreceptors. J Neurophysiol 68: 745-755, 1992.
    • (1992) J Neurophysiol , vol.68 , pp. 745-755
    • Barnes, S.1    Deschênes, M.C.2
  • 14
    • 0024441408 scopus 로고
    • Ionic channels of the inner segment of tiger salamander cone photoreceptors
    • Barnes S, Hille B. Ionic channels of the inner segment of tiger salamander cone photoreceptors. J Gen Physiol 94: 719-743, 1989.
    • (1989) J Gen Physiol , vol.94 , pp. 719-743
    • Barnes, S.1    Hille, B.2
  • 18
    • 77953720612 scopus 로고    scopus 로고
    • Phospholipid scramblase: An update
    • Bevers EM, Williamson PL. Phospholipid scramblase: an update. FEBS Lett 584: 2724-2730, 2010.
    • (2010) FEBS Lett , vol.584 , pp. 2724-2730
    • Bevers, E.M.1    Williamson, P.L.2
  • 20
    • 2942564430 scopus 로고    scopus 로고
    • Prediction of posttranslational glycosylation and phosphorylation of proteins from the amino acid sequence
    • Blom N, Sicheritz-Pontén T, Gupta R, Gammeltoft S, Brunak S. Prediction of posttranslational glycosylation and phosphorylation of proteins from the amino acid sequence. Proteomics 4: 1633-1649, 2004.
    • (2004) Proteomics , vol.4 , pp. 1633-1649
    • Blom, N.1    Sicheritz-Pontén, T.2    Gupta, R.3    Gammeltoft, S.4    Brunak, S.5
  • 21
    • 34447567192 scopus 로고    scopus 로고
    • 2+-activated Cl-currents in isolated mouse olfactory sensory neurons
    • 2+-activated Cl-currents in isolated mouse olfactory sensory neurons. J Neurophysiol 98: 153-160, 2007.
    • (2007) J Neurophysiol , vol.98 , pp. 153-160
    • Boccaccio, A.1    Menini, A.2
  • 26
    • 84899750733 scopus 로고    scopus 로고
    • Anoctamin 1 induces calcium-activated chloride secretion and proliferation of renal cyst-forming epithelial cells
    • doi: 10.1038/ki.2013.418
    • Buchholz B, Faria D, Schley G, Schreiber R, Eckardt KU, Kunzelmann K. Anoctamin 1 induces calcium-activated chloride secretion and proliferation of renal cyst-forming epithelial cells. Kidney Int doi: 10.1038/ki.2013.418, 2013.
    • (2013) Kidney Int
    • Buchholz, B.1    Faria, D.2    Schley, G.3    Schreiber, R.4    Eckardt, K.U.5    Kunzelmann, K.6
  • 27
    • 0023159130 scopus 로고
    • Action of noradrenaline on single smooth muscle cells freshly dispersed from the rat anococcygeus muscle
    • Byrne NG, Large WA. Action of noradrenaline on single smooth muscle cells freshly dispersed from the rat anococcygeus muscle. J Physiol 389: 513-525, 1987.
    • (1987) J Physiol , vol.389 , pp. 513-525
    • Byrne, N.G.1    Large, W.A.2
  • 30
    • 0034282395 scopus 로고    scopus 로고
    • Myo-Inositol 3,4,5,6-tetrakisphosphate inhibits an apical calcium-activated chloride conductance in polarized monolayers of a cystic fibrosis cell line
    • Carew MA, Yang X, Schultz C, Shears SB. myo-Inositol 3,4,5,6-tetrakisphosphate inhibits an apical calcium-activated chloride conductance in polarized monolayers of a cystic fibrosis cell line. J Biol Chem 275: 26906-26913, 2000.
    • (2000) J Biol Chem , vol.275 , pp. 26906-26913
    • Carew, M.A.1    Yang, X.2    Schultz, C.3    Shears, S.B.4
  • 31
    • 79955974150 scopus 로고    scopus 로고
    • Compound heterozygosity for 2 novel TMEM16F mutations in a patient with Scott syndrome
    • Castoldi E, Collins PW, Williamson PL, Bevers EM. Compound heterozygosity for 2 novel TMEM16F mutations in a patient with Scott syndrome. Blood 117: 4399-4400, 2011.
    • (2011) Blood , vol.117 , pp. 4399-4400
    • Castoldi, E.1    Collins, P.W.2    Williamson, P.L.3    Bevers, E.M.4
  • 36
    • 0029763624 scopus 로고    scopus 로고
    • Effect of niflumic acid on noradrenaline-induced contractions of the rat aorta
    • Criddle DN, de Moura RS, Greenwood IA, Large WA. Effect of niflumic acid on noradrenaline-induced contractions of the rat aorta. Br J Pharmacol 118: 1065-1071, 1996.
    • (1996) Br J Pharmacol , vol.118 , pp. 1065-1071
    • Criddle, D.N.1    de Moura, R.S.2    Greenwood, I.A.3    Large, W.A.4
  • 37
    • 8044242326 scopus 로고    scopus 로고
    • Inhibitory action of niflumic acid on noradrenaline-and 5-hydroxytryptamine-induced pressor responses in the isolated mesenteric vascular bed of the rat
    • Criddle DN, de Moura RS, Greenwood IA, Large WA. Inhibitory action of niflumic acid on noradrenaline-and 5-hydroxytryptamine-induced pressor responses in the isolated mesenteric vascular bed of the rat. Br J Pharmacol 120: 813-818, 1997.
    • (1997) Br J Pharmacol , vol.120 , pp. 813-818
    • Criddle, D.N.1    de Moura, R.S.2    Greenwood, I.A.3    Large, W.A.4
  • 38
    • 0346057816 scopus 로고    scopus 로고
    • 2+ from an intracellular store in rat pulmonary artery smooth muscle cells
    • 2+ from an intracellular store in rat pulmonary artery smooth muscle cells. Br J Pharmacol 140: 1442-1450, 2003.
    • (2003) Br J Pharmacol , vol.140 , pp. 1442-1450
    • Cruickshank, S.F.1    Baxter, L.M.2    Drummond, R.M.3
  • 39
    • 84886530690 scopus 로고    scopus 로고
    • A distinct mechanism for activating uncoupled nicotinic acetylcholine receptors
    • Dacosta CJ, Dey L, Therien JP, Baenziger JE. A distinct mechanism for activating uncoupled nicotinic acetylcholine receptors. Nat Chem Biol 9: 701-707, 2013.
    • (2013) Nat Chem Biol , vol.9 , pp. 701-707
    • Dacosta, C.J.1    Dey, L.2    Therien, J.P.3    Baenziger, J.E.4
  • 41
    • 51049091445 scopus 로고    scopus 로고
    • Topology of NGEP, a prostate-specific cell:Cell junction protein widely expressed in many cancers of different grade level
    • Das S, Hahn Y, Walker DA, Nagata S, Willingham MC, Peehl DM, Bera TK, Lee B, Pastan I. Topology of NGEP, a prostate-specific cell:cell junction protein widely expressed in many cancers of different grade level. Cancer Res 68: 6306-6312, 2008.
    • (2008) Cancer Res , vol.68 , pp. 6306-6312
    • Das, S.1    Hahn, Y.2    Walker, D.A.3    Nagata, S.4    Willingham, M.C.5    Peehl, D.M.6    Bera, T.K.7    Lee, B.8    Pastan, I.9
  • 44
    • 40849100330 scopus 로고    scopus 로고
    • Small-molecule screen identifies inhibitors of a human intestinal calcium-activated chloride channel
    • De La Fuente R, Namkung W, Mills A, Verkman AS. Small-molecule screen identifies inhibitors of a human intestinal calcium-activated chloride channel. Mol Pharmacol 73: 758-768, 2008.
    • (2008) Mol Pharmacol , vol.73 , pp. 758-768
    • De La Fuente, R.1    Namkung, W.2    Mills, A.3    Verkman, A.S.4
  • 45
    • 0022551009 scopus 로고
    • Mechanism of chloride secretion induced by carbachol in a colonic epithelial cell line
    • Dharmsathaphorn K, Pandol SJ. Mechanism of chloride secretion induced by carbachol in a colonic epithelial cell line. J Clin Invest 77: 348-354, 1986.
    • (1986) J Clin Invest , vol.77 , pp. 348-354
    • Dharmsathaphorn, K.1    Pandol, S.J.2
  • 56
    • 0033590083 scopus 로고    scopus 로고
    • Phosphatidylserine exposure during apoptosis is a cell-type-specific event and does not correlate with plasma membrane phospholipid scramblase expression
    • Fadeel B, Gleiss B, Högstrand K, Chandra J, Wiedmer T, Sims PJ, Henter JI, Orrenius S, Samali A. Phosphatidylserine exposure during apoptosis is a cell-type-specific event and does not correlate with plasma membrane phospholipid scramblase expression. Biochem Biophys Res Commun 266: 504-511, 1999.
    • (1999) Biochem Biophys Res Commun , vol.266 , pp. 504-511
    • Fadeel, B.1    Gleiss, B.2    Högstrand, K.3    Chandra, J.4    Wiedmer, T.5    Sims, P.J.6    Henter, J.I.7    Orrenius, S.8    Samali, A.9
  • 59
    • 23744514549 scopus 로고    scopus 로고
    • Rapid increase in plasma membrane chloride permeability during wound resealing in starfish oocytes
    • Fein A, Terasaki M. Rapid increase in plasma membrane chloride permeability during wound resealing in starfish oocytes. J Gen Physiol 126: 151-159, 2005.
    • (2005) J Gen Physiol , vol.126 , pp. 151-159
    • Fein, A.1    Terasaki, M.2
  • 62
    • 77957335524 scopus 로고    scopus 로고
    • CFTR and calciumactivated chloride channels in primary cultures of human airway gland cells of serous or mucous phenotype
    • Fischer H, Illek B, Sachs L, Finkbeiner WE, Widdicombe JH. CFTR and calciumactivated chloride channels in primary cultures of human airway gland cells of serous or mucous phenotype. Am J Physiol Lung Cell Mol Physiol 299: L585-L594, 2010.
    • (2010) Am J Physiol Lung Cell Mol Physiol , vol.299
    • Fischer, H.1    Illek, B.2    Sachs, L.3    Finkbeiner, W.E.4    Widdicombe, J.H.5
  • 63
    • 78649736185 scopus 로고    scopus 로고
    • Vascular smooth muscle phenotype diversity and function
    • Fisher SA. Vascular smooth muscle phenotype diversity and function. Physiol Genomics 42A: 169-187, 2010.
    • (2010) Physiol Genomics , vol.42 A , pp. 169-187
    • Fisher, S.A.1
  • 65
    • 78651254773 scopus 로고    scopus 로고
    • Spatial distribution of calcium-gated chloride channels in olfactory cilia
    • French DA, Badamdorj D, Kleene SJ. Spatial distribution of calcium-gated chloride channels in olfactory cilia. PLoS One 5: e15676, 2010.
    • (2010) PLoS One , vol.5
    • French, D.A.1    Badamdorj, D.2    Kleene, S.J.3
  • 68
    • 33644628177 scopus 로고    scopus 로고
    • Phylogeny of the TMEM16 protein family: Some members are overexpressed in cancer
    • Galindo BE, Vacquier VD. Phylogeny of the TMEM16 protein family: some members are overexpressed in cancer. Int J Mol Med 16: 919-924, 2005.
    • (2005) Int J Mol Med , vol.16 , pp. 919-924
    • Galindo, B.E.1    Vacquier, V.D.2
  • 69
    • 70349223856 scopus 로고    scopus 로고
    • Normal mouse intestinal mucus release requires cystic fibrosis transmembrane regulator-dependent bicarbonate secretion
    • Garcia MA, Yang N, Quinton PM. Normal mouse intestinal mucus release requires cystic fibrosis transmembrane regulator-dependent bicarbonate secretion. J Clin Invest 119: 2613-2622, 2009.
    • (2009) J Clin Invest , vol.119 , pp. 2613-2622
    • Garcia, M.A.1    Yang, N.2    Quinton, P.M.3
  • 71
    • 1842375102 scopus 로고    scopus 로고
    • Calcium dependence and distribution of calcium-activated chloride channels in Xenopus oocytes
    • Gomez-Hernandez JM, Stühmer W, Parekh AB. Calcium dependence and distribution of calcium-activated chloride channels in Xenopus oocytes. J Physiol 502: 569-574, 1997.
    • (1997) J Physiol , vol.502 , pp. 569-574
    • Gomez-Hernandez, J.M.1    Stühmer, W.2    Parekh, A.B.3
  • 74
    • 4644310508 scopus 로고    scopus 로고
    • Calcineurin Aα but not Aβ augments ICl(Ca) in rabbit pulmonary artery smooth muscle cells
    • Greenwood IA, Ledoux J, Sanguinetti A, Perrino BA, Leblanc N. Calcineurin Aα but not Aβ augments ICl(Ca) in rabbit pulmonary artery smooth muscle cells. J Biol Chem 279: 38830-38837, 2004.
    • (2004) J Biol Chem , vol.279 , pp. 38830-38837
    • Greenwood, I.A.1    Ledoux, J.2    Sanguinetti, A.3    Perrino, B.A.4    Leblanc, N.5
  • 78
    • 79959791265 scopus 로고    scopus 로고
    • The non-selective monovalent cationic channels TRPM4 and TRPM5
    • Guinamard R, Sallé L, Simard C. The non-selective monovalent cationic channels TRPM4 and TRPM5. Adv Exp Med Biol 704: 147-171, 2011.
    • (2011) Adv Exp Med Biol , vol.704 , pp. 147-171
    • Guinamard, R.1    Sallé, L.2    Simard, C.3
  • 79
    • 34548009359 scopus 로고    scopus 로고
    • Dysferlin and muscle membrane repair
    • Han R, Campbell KP. Dysferlin and muscle membrane repair. Curr Opin Cell Biol 19: 409-416, 2007.
    • (2007) Curr Opin Cell Biol , vol.19 , pp. 409-416
    • Han, R.1    Campbell, K.P.2
  • 85
    • 0035378310 scopus 로고    scopus 로고
    • Regulation of a human chloride channel. A paradigm for integrating input from calcium, type II calmodulin-dependent protein kinase, and inositol 3,4,5,6-tetrakisphosphate
    • Ho MW, Kaetzel MA, Armstrong DL, Shears SB. Regulation of a human chloride channel. A paradigm for integrating input from calcium, type II calmodulin-dependent protein kinase, and inositol 3,4,5,6-tetrakisphosphate. J Biol Chem 276: 18673-18680, 2001.
    • (2001) J Biol Chem , vol.276 , pp. 18673-18680
    • Ho, M.W.1    Kaetzel, M.A.2    Armstrong, D.L.3    Shears, S.B.4
  • 90
    • 84859645387 scopus 로고    scopus 로고
    • Calcium-activated chloride channels (CaCCs) regulate action potential and synaptic response in hippocampal neurons
    • Huang WC, Xiao S, Huang F, Harfe BD, Jan YN, Jan LY. Calcium-activated chloride channels (CaCCs) regulate action potential and synaptic response in hippocampal neurons. Neuron 74: 179-192, 2012.
    • (2012) Neuron , vol.74 , pp. 179-192
    • Huang, W.C.1    Xiao, S.2    Huang, F.3    Harfe, B.D.4    Jan, Y.N.5    Jan, L.Y.6
  • 91
    • 33748948544 scopus 로고    scopus 로고
    • Comprehensive genome and transcriptome analysis of the 11q13 amplicon in human oral cancer and synteny to the 7F5 amplicon in murine oral carcinoma
    • Huang X, Godfrey TE, Gooding WE, McCarty KS Jr, Gollin SM. Comprehensive genome and transcriptome analysis of the 11q13 amplicon in human oral cancer and synteny to the 7F5 amplicon in murine oral carcinoma. Genes Chromosomes Cancer 45: 1058-1069, 2006.
    • (2006) Genes Chromosomes Cancer , vol.45 , pp. 1058-1069
    • Huang, X.1    Godfrey, T.E.2    Gooding, W.E.3    McCarty Jr., K.S.4    Gollin, S.M.5
  • 92
    • 0035195884 scopus 로고    scopus 로고
    • Physiology and pathophysiology of the interstitial cell of Cajal: From bench to bedside. II. Gastric motility: Lessons from mutant mice on slow waves and innervation
    • Huizinga JD. Physiology and pathophysiology of the interstitial cell of Cajal: from bench to bedside. II. Gastric motility: lessons from mutant mice on slow waves and innervation. Am J Physiol Gastrointest Liver Physiol 281: G1129-G1134, 2001.
    • (2001) Am J Physiol Gastrointest Liver Physiol , vol.281
    • Huizinga, J.D.1
  • 93
    • 33745866891 scopus 로고    scopus 로고
    • Trophoblast fusion: Fusogenic proteins, syncytins and ADAMs, and other prerequisites for syncytial fusion
    • Huppertz B, Bartz C, Kokozidou M. Trophoblast fusion: fusogenic proteins, syncytins and ADAMs, and other prerequisites for syncytial fusion. Micron 37: 509-517, 2006.
    • (2006) Micron , vol.37 , pp. 509-517
    • Huppertz, B.1    Bartz, C.2    Kokozidou, M.3
  • 96
    • 0027744280 scopus 로고
    • Volume-sensitive anion channels mediate swelling-activated inositol and taurine efflux
    • Jackson PS, Strange K. Volume-sensitive anion channels mediate swelling-activated inositol and taurine efflux. Am J Physiol Cell Physiol 265: C1489-C1500, 1993.
    • (1993) Am J Physiol Cell Physiol , vol.265
    • Jackson, P.S.1    Strange, K.2
  • 97
    • 0029034204 scopus 로고
    • Characterization of the voltage-dependent properties of a volume-sensitive anion conductance
    • Jackson PS, Strange K. Characterization of the voltage-dependent properties of a volume-sensitive anion conductance. J Gen Physiol 105: 661-676, 1995.
    • (1995) J Gen Physiol , vol.105 , pp. 661-676
    • Jackson, P.S.1    Strange, K.2
  • 98
    • 0027253890 scopus 로고
    • + currents in guinea-pig tracheal myocytes: Convergence with muscarinic signalling pathway
    • + currents in guinea-pig tracheal myocytes: convergence with muscarinic signalling pathway. J Physiol 465: 661-677, 1993.
    • (1993) J Physiol , vol.465 , pp. 661-677
    • Janssen, L.J.1    Sims, S.M.2
  • 100
    • 2442672680 scopus 로고    scopus 로고
    • Electrophysiological characterization and functional importance of calcium-activated chloride channel in rat uterine myocytes
    • Jones K, Shmygol A, Kupittayanant S, Wray S. Electrophysiological characterization and functional importance of calcium-activated chloride channel in rat uterine myocytes. Pflügers Arch 448: 36-43, 2004.
    • (2004) Pflügers Arch , vol.448 , pp. 36-43
    • Jones, K.1    Shmygol, A.2    Kupittayanant, S.3    Wray, S.4
  • 102
    • 33744491261 scopus 로고    scopus 로고
    • Calmodulin contributes to gating control in olfactory calcium-activated chloride channels
    • Kaneko H, Möhrlen F, Frings S. Calmodulin contributes to gating control in olfactory calcium-activated chloride channels. J Gen Physiol 127: 737-748, 2006.
    • (2006) J Gen Physiol , vol.127 , pp. 737-748
    • Kaneko, H.1    Möhrlen, F.2    Frings, S.3
  • 104
    • 84900399323 scopus 로고    scopus 로고
    • Deranged calcium signaling in purkinje cells and pathogenesis in spinocerebellar ataxia 2 (SCA2) and other ataxias
    • [PMID: 20480274]
    • Kasumu A, Bezprozvanny I. Deranged calcium signaling in purkinje cells and pathogenesis in spinocerebellar ataxia 2 (SCA2) and other ataxias. Cerebellum 2010. [PMID: 20480274].
    • (2010) Cerebellum
    • Kasumu, A.1    Bezprozvanny, I.2
  • 105
    • 0037172775 scopus 로고    scopus 로고
    • Transbilayer asymmetry of phospholipids in the plasma membrane regulates exocytotic release in mast cells
    • Kato N, Nakanishi M, Hirashima N. Transbilayer asymmetry of phospholipids in the plasma membrane regulates exocytotic release in mast cells. Biochemistry 41: 8068-8074, 2002.
    • (2002) Biochemistry , vol.41 , pp. 8068-8074
    • Kato, N.1    Nakanishi, M.2    Hirashima, N.3
  • 106
    • 0042628162 scopus 로고    scopus 로고
    • FLJ10261 gene, located within the CCND1-EMS1 locus on human chromosome 11q13, encodes the eight-transmembrane protein homologous to C12orf3, C11orf25 and FLJ34272 gene products
    • Katoh M, Katoh M. FLJ10261 gene, located within the CCND1-EMS1 locus on human chromosome 11q13, encodes the eight-transmembrane protein homologous to C12orf3, C11orf25 and FLJ34272 gene products. Int J Oncol 22: 1375-1381, 2003.
    • (2003) Int J Oncol , vol.22 , pp. 1375-1381
    • Katoh, M.1    Katoh, M.2
  • 107
    • 0033660893 scopus 로고    scopus 로고
    • 2+ and Cl-channel activation in secretory cells
    • 2+ and Cl-channel activation in secretory cells. Annu Rev Physiol 62: 493-513, 2000.
    • (2000) Annu Rev Physiol , vol.62 , pp. 493-513
    • Kidd, J.F.1    Thorn, P.2
  • 108
    • 79959572617 scopus 로고    scopus 로고
    • Requirement of calcium-activated chloride channels in the activation of mouse vomeronasal neurons
    • Kim S, Ma L, Yu CR. Requirement of calcium-activated chloride channels in the activation of mouse vomeronasal neurons. Nat Commun 2: 365, 2011.
    • (2011) Nat Commun , vol.2 , pp. 365
    • Kim, S.1    Ma, L.2    Yu, C.R.3
  • 109
    • 13844311439 scopus 로고    scopus 로고
    • Interaction among Btn1p, Btn2p, and Ist2p reveals potential interplay among the vacuole, amino acid levels, and ion homeostasis in the yeast Saccharomyces cerevisiae
    • Kim Y, Chattopadhyay S, Locke S, Pearce DA. Interaction among Btn1p, Btn2p, and Ist2p reveals potential interplay among the vacuole, amino acid levels, and ion homeostasis in the yeast Saccharomyces cerevisiae. Eukaryot Cell 4: 281-288, 2005.
    • (2005) Eukaryot Cell , vol.4 , pp. 281-288
    • Kim, Y.1    Chattopadhyay, S.2    Locke, S.3    Pearce, D.A.4
  • 110
    • 0027270769 scopus 로고
    • Origin of the chloride current in olfactory transduction
    • Kleene SJ. Origin of the chloride current in olfactory transduction. Neuron 11: 123-132, 1993.
    • (1993) Neuron , vol.11 , pp. 123-132
    • Kleene, S.J.1
  • 111
    • 0025719977 scopus 로고
    • Calcium-activated chloride conductance in frog olfactory cilia
    • Kleene SJ, Gesteland RC. Calcium-activated chloride conductance in frog olfactory cilia. J Neurosci 11: 3624-3629, 1991.
    • (1991) J Neurosci , vol.11 , pp. 3624-3629
    • Kleene, S.J.1    Gesteland, R.C.2
  • 113
    • 84902295743 scopus 로고    scopus 로고
    • Chloride channel inhibition by a red wine extract and a synthetic small molecule prevents rotaviral secretory diarrhoea in neonatal mice
    • doi: 10.1136/gutjnl-2013-3056
    • Ko EA, Jin BJ, Namkung W, Ma T, Thiagarajah JR, Verkman AS. Chloride channel inhibition by a red wine extract and a synthetic small molecule prevents rotaviral secretory diarrhoea in neonatal mice. Gut doi: 10.1136/gutjnl-2013-3056, 2013.
    • (2013) Gut
    • Ko, E.A.1    Jin, B.J.2    Namkung, W.3    Ma, T.4    Thiagarajah, J.R.5    Verkman, A.S.6
  • 115
    • 0026701875 scopus 로고
    • Volume-regulatory Cl-channel currents in cultured human epithelial cells
    • Kubo M, Okada Y. Volume-regulatory Cl-channel currents in cultured human epithelial cells. J Physiol 456: 351-371, 1992.
    • (1992) J Physiol , vol.456 , pp. 351-371
    • Kubo, M.1    Okada, Y.2
  • 117
    • 0024325933 scopus 로고
    • Properties and regulation of chloride channels in cystic fibrosis and normal airway cells
    • Kunzelmann K, Pavenstädt H, Greger R. Properties and regulation of chloride channels in cystic fibrosis and normal airway cells. Pflügers Arch 415: 172-182, 1989.
    • (1989) Pflügers Arch , vol.415 , pp. 172-182
    • Kunzelmann, K.1    Pavenstädt, H.2    Greger, R.3
  • 119
    • 0027910432 scopus 로고
    • Co-existence of cationic and chloride components in odorantinduced current of vertebrate olfactory receptor cells
    • Kurahashi T, Yau KW. Co-existence of cationic and chloride components in odorantinduced current of vertebrate olfactory receptor cells. Nature 363: 71-74, 1993.
    • (1993) Nature , vol.363 , pp. 71-74
    • Kurahashi, T.1    Yau, K.W.2
  • 121
    • 76149124216 scopus 로고    scopus 로고
    • Mucus hypersecretion in asthma: Intracellular signalling pathways as targets for pharmacotherapy
    • Lai HY, Rogers DF. Mucus hypersecretion in asthma: intracellular signalling pathways as targets for pharmacotherapy. Curr Opin Allergy Clin Immunol 10: 67-76, 2010.
    • (2010) Curr Opin Allergy Clin Immunol , vol.10 , pp. 67-76
    • Lai, H.Y.1    Rogers, D.F.2
  • 122
    • 33750848735 scopus 로고    scopus 로고
    • Chloride ion currents contribute functionally to norepinephrineinduced vascular contraction
    • Lamb FS, Barna TJ. Chloride ion currents contribute functionally to norepinephrineinduced vascular contraction. Am J Physiol Heart Circ Physiol 275: H151-H160, 1998.
    • (1998) Am J Physiol Heart Circ Physiol , vol.275
    • Lamb, F.S.1    Barna, T.J.2
  • 125
    • 11244319588 scopus 로고    scopus 로고
    • 2+-dependent Cl-channel modulation by niflumic acid in rabbit coronary arterial myocytes
    • 2+-dependent Cl-channel modulation by niflumic acid in rabbit coronary arterial myocytes. Mol Pharmacol 67: 163-173, 2005.
    • (2005) Mol Pharmacol , vol.67 , pp. 163-173
    • Ledoux, J.1    Greenwood, I.A.2    Leblanc, N.3
  • 127
    • 80053429773 scopus 로고    scopus 로고
    • Platelet membrane phospholipid asymmetry: From the characterization of a scramblase activity to the identification of an essential protein mutated in Scott syndrome
    • Lhermusier T, Chap H, Payrastre B. Platelet membrane phospholipid asymmetry: from the characterization of a scramblase activity to the identification of an essential protein mutated in Scott syndrome. J Thromb Haemost 9: 1883-1891, 2011.
    • (2011) J Thromb Haemost , vol.9 , pp. 1883-1891
    • Lhermusier, T.1    Chap, H.2    Payrastre, B.3
  • 129
    • 84866143707 scopus 로고    scopus 로고
    • 2+-activated Cl-channel ANO1/TMEM16A expression suppresses tumor growth and invasiveness in human prostate carcinoma
    • 2+-activated Cl-channel ANO1/TMEM16A expression suppresses tumor growth and invasiveness in human prostate carcinoma. Cancer Lett 326: 41-51, 2012.
    • (2012) Cancer Lett , vol.326 , pp. 41-51
    • Liu, W.1    Lu, M.2    Liu, B.3    Huang, Y.4    Wang, K.5
  • 130
    • 0027491955 scopus 로고
    • Nonlinear amplification by calcium-dependent chloride channels in olfactory receptor cells
    • Lowe G, Gold GH. Nonlinear amplification by calcium-dependent chloride channels in olfactory receptor cells. Nature 366: 283-286, 1993.
    • (1993) Nature , vol.366 , pp. 283-286
    • Lowe, G.1    Gold, G.H.2
  • 131
    • 0037040875 scopus 로고    scopus 로고
    • Anionic phospholipids regulate native and expressed epithelial sodium channel (ENaC)
    • Ma HP, Saxena S, Warnock DG. Anionic phospholipids regulate native and expressed epithelial sodium channel (ENaC). J Biol Chem 277: 7641-7644, 2002.
    • (2002) J Biol Chem , vol.277 , pp. 7641-7644
    • Ma, H.P.1    Saxena, S.2    Warnock, D.G.3
  • 132
    • 0036896008 scopus 로고    scopus 로고
    • Thiazolidinone CFTR inhibitor identified by high-throughput screening blocks cholera toxin-induced intestinal fluid secretion
    • Ma T, Thiagarajah JR, Yang H, Sonawane ND, Folli C, Galietta LJ, Verkman AS. Thiazolidinone CFTR inhibitor identified by high-throughput screening blocks cholera toxin-induced intestinal fluid secretion. J Clin Invest 110: 1651-1658, 2002.
    • (2002) J Clin Invest , vol.110 , pp. 1651-1658
    • Ma, T.1    Thiagarajah, J.R.2    Yang, H.3    Sonawane, N.D.4    Folli, C.5    Galietta, L.J.6    Verkman, A.S.7
  • 133
    • 34447562617 scopus 로고    scopus 로고
    • Ion channel compartments in photoreceptors: Evidence from salamander rods with intact and ablated terminals
    • MacLeish PR, Nurse CA. Ion channel compartments in photoreceptors: evidence from salamander rods with intact and ablated terminals. J Neurophysiol 98: 86-95, 2007.
    • (2007) J Neurophysiol , vol.98 , pp. 86-95
    • McLeish, P.R.1    Nurse, C.A.2
  • 136
    • 84870793680 scopus 로고    scopus 로고
    • ER-to-plasma membrane tethering proteins regulate cell signaling and ER morphology
    • Manford AG, Stefan CJ, Yuan HL, Macgurn JA, Emr SD. ER-to-plasma membrane tethering proteins regulate cell signaling and ER morphology. Dev Cell 23: 1129-1140, 2012.
    • (2012) Dev Cell , vol.23 , pp. 1129-1140
    • Manford, A.G.1    Stefan, C.J.2    Yuan, H.L.3    McGurn, J.A.4    Emr, S.D.5
  • 137
    • 77954517197 scopus 로고    scopus 로고
    • TMEM16A/anoctamin 1 protein mediates calcium-activated chloride currents in pulmonary arterial smooth muscle cells
    • Manoury B, Tamuleviciute A, Tammaro P. TMEM16A/anoctamin 1 protein mediates calcium-activated chloride currents in pulmonary arterial smooth muscle cells. J Physiol 588: 2305-2314, 2010.
    • (2010) J Physiol , vol.588 , pp. 2305-2314
    • Manoury, B.1    Tamuleviciute, A.2    Tammaro, P.3
  • 140
    • 0025845558 scopus 로고
    • Regulation of transepithelial ion transport and intracellular calcium by extracellular ATP in human normal and cystic fibrosis airway epithelium
    • Mason SJ, Paradiso AM, Boucher RC. Regulation of transepithelial ion transport and intracellular calcium by extracellular ATP in human normal and cystic fibrosis airway epithelium. Br J Pharmacol 103: 1649-1656, 1991.
    • (1991) Br J Pharmacol , vol.103 , pp. 1649-1656
    • Mason, S.J.1    Paradiso, A.M.2    Boucher, R.C.3
  • 141
    • 0842282987 scopus 로고    scopus 로고
    • A cyclic GMP-dependent calcium-activated chloride current in smooth-muscle cells from rat mesenteric resistance arteries
    • Matchkov VV, Aalkjaer C, Nilsson H. A cyclic GMP-dependent calcium-activated chloride current in smooth-muscle cells from rat mesenteric resistance arteries. J Gen Physiol 123: 121-134, 2004.
    • (2004) J Gen Physiol , vol.123 , pp. 121-134
    • Matchkov, V.V.1    Aalkjaer, C.2    Nilsson, H.3
  • 142
    • 27744472078 scopus 로고    scopus 로고
    • 2+-activated Cl-conductances in smooth muscle cells from different vascular beds and colon
    • 2+-activated Cl-conductances in smooth muscle cells from different vascular beds and colon. Pflügers Arch 451: 371-379, 2005.
    • (2005) Pflügers Arch , vol.451 , pp. 371-379
    • Matchkov, V.V.1    Aalkjaer, C.2    Nilsson, H.3
  • 143
    • 0032433707 scopus 로고    scopus 로고
    • Evidence for periciliary liquid layer depletion, not abnormal ion composition, in the pathogenesis of cystic fibrosis airways disease
    • Matsui H, Grubb BR, Tarran R, Randell SH, Gatzy JT, Davis CW, Boucher RC. Evidence for periciliary liquid layer depletion, not abnormal ion composition, in the pathogenesis of cystic fibrosis airways disease. Cell 95: 1005-1015, 1998.
    • (1998) Cell , vol.95 , pp. 1005-1015
    • Matsui, H.1    Grubb, B.R.2    Tarran, R.3    Randell, S.H.4    Gatzy, J.T.5    Davis, C.W.6    Boucher, R.C.7
  • 146
    • 0028181053 scopus 로고
    • Carbachol stimulates Cl-secretion via activation of two distinct apical Cl-pathways in cultured human T84 intestinal epithelial monolayers
    • McEwan GT, Hirst BH, Simmons NL. Carbachol stimulates Cl-secretion via activation of two distinct apical Cl-pathways in cultured human T84 intestinal epithelial monolayers. Biochim Biophys Acta 1220: 241-247, 1994.
    • (1994) Biochim Biophys Acta , vol.1220 , pp. 241-247
    • McEwan, G.T.1    Hirst, B.H.2    Simmons, N.L.3
  • 147
    • 78651427847 scopus 로고    scopus 로고
    • Location of release sites and calcium-activated chloride channels relative to calcium channels at the photoreceptor ribbon synapse
    • Mercer AJ, Rabl K, Riccardi GE, Brecha NC, Stella SL Jr, Thoreson WB. Location of release sites and calcium-activated chloride channels relative to calcium channels at the photoreceptor ribbon synapse. J Neurophysiol 105: 321-335, 2011.
    • (2011) J Neurophysiol , vol.105 , pp. 321-335
    • Mercer, A.J.1    Rabl, K.2    Riccardi, G.E.3    Brecha, N.C.4    Stella Jr., S.L.5    Thoreson, W.B.6
  • 150
  • 152
    • 84859710006 scopus 로고    scopus 로고
    • 2+-dependent Cl-conductance and TMEM16A expression in intestinal epithelial cells
    • 2+-dependent Cl-conductance and TMEM16A expression in intestinal epithelial cells. J Physiol 590: 1907-1920, 2012.
    • (2012) J Physiol , vol.590 , pp. 1907-1920
    • Mroz, M.S.1    Keely, S.J.2
  • 153
    • 3843066593 scopus 로고    scopus 로고
    • Discovery of glycine hydrazide pore-occluding CFTR inhibitors: Mechanism, structure-activity analysis, and in vivo efficacy
    • Muanprasat C, Sonawane ND, Salinas D, Taddei A, Galietta LJ, Verkman AS. Discovery of glycine hydrazide pore-occluding CFTR inhibitors: mechanism, structure-activity analysis, and in vivo efficacy. J Gen Physiol 124: 125-137, 2004.
    • (2004) J Gen Physiol , vol.124 , pp. 125-137
    • Muanprasat, C.1    Sonawane, N.D.2    Salinas, D.3    Taddei, A.4    Galietta, L.J.5    Verkman, A.S.6
  • 154
    • 0023111437 scopus 로고
    • A cyclic nucleotide-gated conductance in olfactory receptor cilia
    • Nakamura T, Gold GH. A cyclic nucleotide-gated conductance in olfactory receptor cilia. Nature 325: 442-444, 1987.
    • (1987) Nature , vol.325 , pp. 442-444
    • Nakamura, T.1    Gold, G.H.2
  • 155
    • 78751478642 scopus 로고    scopus 로고
    • TMEM16A inhibitors reveal TMEM16A as a minor component of calcium-activated chloride channel conductance in airway and intestinal epithelial cells
    • Namkung W, Phuan PW, Verkman AS. TMEM16A inhibitors reveal TMEM16A as a minor component of calcium-activated chloride channel conductance in airway and intestinal epithelial cells. J Biol Chem 286: 2365-2374, 2011.
    • (2011) J Biol Chem , vol.286 , pp. 2365-2374
    • Namkung, W.1    Phuan, P.W.2    Verkman, A.S.3
  • 156
    • 78649892982 scopus 로고    scopus 로고
    • 2+-activated Cl-channels by gallotannins as a possible molecular basis for health benefits of red wine and green tea
    • 2+-activated Cl-channels by gallotannins as a possible molecular basis for health benefits of red wine and green tea. FASEB J 24: 4178-4186, 2010.
    • (2010) FASEB J , vol.24 , pp. 4178-4186
    • Namkung, W.1    Thiagarajah, J.R.2    Phuan, P.W.3    Verkman, A.S.4
  • 157
    • 80355129636 scopus 로고    scopus 로고
    • Small-molecule activators of TMEM16A, a calcium-activated chloride channel, stimulate epithelial chloride secretion and intestinal contraction
    • Namkung W, Yao Z, Finkbeiner WE, Verkman AS. Small-molecule activators of TMEM16A, a calcium-activated chloride channel, stimulate epithelial chloride secretion and intestinal contraction. FASEB J 25: 4048-4062, 2011.
    • (2011) FASEB J , vol.25 , pp. 4048-4062
    • Namkung, W.1    Yao, Z.2    Finkbeiner, W.E.3    Verkman, A.S.4
  • 158
    • 34248213042 scopus 로고    scopus 로고
    • PkaPS: Prediction of protein kinase A phosphorylation sites with the simplified kinase-substrate binding model
    • Neuberger G, Schneider G, Eisenhaber F. pkaPS: prediction of protein kinase A phosphorylation sites with the simplified kinase-substrate binding model. Biol Direct 2: 1, 2007.
    • (2007) Biol Direct , vol.2 , pp. 1
    • Neuberger, G.1    Schneider, G.2    Eisenhaber, F.3
  • 159
    • 34548717686 scopus 로고    scopus 로고
    • Mechanisms of neuronal chloride accumulation in intact mouse olfactory epithelium
    • Nickell WT, Kleene NK, Kleene SJ. Mechanisms of neuronal chloride accumulation in intact mouse olfactory epithelium. J Physiol 583: 1005-1020, 2007.
    • (2007) J Physiol , vol.583 , pp. 1005-1020
    • Nickell, W.T.1    Kleene, N.K.2    Kleene, S.J.3
  • 161
    • 79961105324 scopus 로고    scopus 로고
    • Increased complexity of Tmem16a/Anoctamin 1 transcript alternative splicing
    • O'Driscoll KE, Pipe RA, Britton FC. Increased complexity of Tmem16a/Anoctamin 1 transcript alternative splicing. BMC Mol Biol 12: 35, 2011.
    • (2011) BMC Mol Biol , vol.12 , pp. 35
    • O'Driscoll, K.E.1    Pipe, R.A.2    Britton, F.C.3
  • 163
    • 0030815584 scopus 로고    scopus 로고
    • Volume expansion-sensing outward-rectifier Cl-channel: Fresh start to the molecular identity and volume sensor
    • Okada Y. Volume expansion-sensing outward-rectifier Cl-channel: fresh start to the molecular identity and volume sensor. Am J Physiol Cell Physiol 273: C755-C789, 1997.
    • (1997) Am J Physiol Cell Physiol , vol.273
    • Okada, Y.1
  • 164
    • 84861715725 scopus 로고    scopus 로고
    • Human spermatozoa possess a calcium-dependent chloride channel that may participate in the acrosomal reaction
    • Orta G, Ferreira G, José O, Treviño CL, Beltrán C, Darszon A. Human spermatozoa possess a calcium-dependent chloride channel that may participate in the acrosomal reaction. J Physiol 590: 2659-2675, 2012.
    • (2012) J Physiol , vol.590 , pp. 2659-2675
    • Orta, G.1    Ferreira, G.2    José, O.3    Treviño, C.L.4    Beltrán, C.5    Darszon, A.6
  • 165
    • 0028053968 scopus 로고
    • Potentiation of large conductance KCa channels by niflumic, flufenamic, and mefenamic acids
    • Ottolia M, Toro L. Potentiation of large conductance KCa channels by niflumic, flufenamic, and mefenamic acids. Biophys J 67: 2272-2279, 1994.
    • (1994) Biophys J , vol.67 , pp. 2272-2279
    • Ottolia, M.1    Toro, L.2
  • 169
    • 0024524255 scopus 로고
    • Noradrenaline activates a calciumactivated chloride conductance and increases the voltage-dependent calcium current in cultured single cells of rat portal vein
    • Pacaud P, Loirand G, Mironneau C, Mironneau J. Noradrenaline activates a calciumactivated chloride conductance and increases the voltage-dependent calcium current in cultured single cells of rat portal vein. Br J Pharmacol 97: 139-146, 1989.
    • (1989) Br J Pharmacol , vol.97 , pp. 139-146
    • Pacaud, P.1    Loirand, G.2    Mironneau, C.3    Mironneau, J.4
  • 172
    • 70349573000 scopus 로고    scopus 로고
    • TMEM16B induces chloride currents activated by calcium in mammalian cells
    • Pifferi S, Dibattista M, Menini A. TMEM16B induces chloride currents activated by calcium in mammalian cells. Pflügers Arch 458: 1023-1038, 2009.
    • (2009) Pflügers Arch , vol.458 , pp. 1023-1038
    • Pifferi, S.1    Dibattista, M.2    Menini, A.3
  • 173
    • 0037275533 scopus 로고    scopus 로고
    • Anomalous effect of anthracene-9-carboxylic acid on calcium-activated chloride currents in rabbit pulmonary artery smooth muscle cells
    • Piper AS, Greenwood IA. Anomalous effect of anthracene-9-carboxylic acid on calcium-activated chloride currents in rabbit pulmonary artery smooth muscle cells. Br J Pharmacol 138: 31-38, 2003.
    • (2003) Br J Pharmacol , vol.138 , pp. 31-38
    • Piper, A.S.1    Greenwood, I.A.2
  • 174
    • 0037440701 scopus 로고    scopus 로고
    • 2+-activated Cl-channels in rabbit pulmonary artery smooth muscle cells
    • 2+-activated Cl-channels in rabbit pulmonary artery smooth muscle cells. J Physiol 547: 181-196, 2003.
    • (2003) J Physiol , vol.547 , pp. 181-196
    • Piper, A.S.1    Large, W.A.2
  • 175
    • 84878655983 scopus 로고    scopus 로고
    • Channel properties of the splicing isoforms of the olfactory calcium-activated chloride channel Anoctamin 2
    • Ponissery Saidu S, Stephan AB, Talaga AK, Zhao H, Reisert J. Channel properties of the splicing isoforms of the olfactory calcium-activated chloride channel Anoctamin 2. J Gen Physiol 141: 691-703, 2013.
    • (2013) J Gen Physiol , vol.141 , pp. 691-703
    • Ponissery Saidu, S.1    Stephan, A.B.2    Talaga, A.K.3    Zhao, H.4    Reisert, J.5
  • 176
    • 0026609888 scopus 로고
    • 2+ release by flufenamic acid and other blockers of the non-selective cation channel
    • 2+ release by flufenamic acid and other blockers of the non-selective cation channel. FEBS Lett 296: 245-248, 1992.
    • (1992) FEBS Lett , vol.296 , pp. 245-248
    • Poronnik, P.1    Ward, M.C.2    Cook, D.I.3
  • 177
    • 0038486816 scopus 로고    scopus 로고
    • 2+-activated Cl-currents in mouse kidney inner medullary collecting duct cells
    • 2+-activated Cl-currents in mouse kidney inner medullary collecting duct cells. Am J Physiol Renal Physiol 285: F326-F335, 2003.
    • (2003) Am J Physiol Renal Physiol , vol.285
    • Qu, Z.1    Wei, R.W.2    Hartzell, H.C.3
  • 179
    • 0141736796 scopus 로고    scopus 로고
    • The Ca-activated Cl channel and its control in rat olfactory receptor neurons
    • Reisert J, Bauer PJ, Yau KW, Frings S. The Ca-activated Cl channel and its control in rat olfactory receptor neurons. J Gen Physiol 122: 349-363, 2003.
    • (2003) J Gen Physiol , vol.122 , pp. 349-363
    • Reisert, J.1    Bauer, P.J.2    Yau, K.W.3    Frings, S.4
  • 180
    • 13844294446 scopus 로고    scopus 로고
    • Mechanism of the excitatory Cl-response in mouse olfactory receptor neurons
    • Reisert J, Lai J, Yau KW, Bradley J. Mechanism of the excitatory Cl-response in mouse olfactory receptor neurons. Neuron 45: 553-561, 2005.
    • (2005) Neuron , vol.45 , pp. 553-561
    • Reisert, J.1    Lai, J.2    Yau, K.W.3    Bradley, J.4
  • 181
    • 50649123290 scopus 로고    scopus 로고
    • CFTR function and prospects for therapy
    • Riordan JR. CFTR function and prospects for therapy. Annu Rev Biochem 77: 701-726, 2008.
    • (2008) Annu Rev Biochem , vol.77 , pp. 701-726
    • Riordan, J.R.1
  • 182
    • 49049118639 scopus 로고    scopus 로고
    • The transmembrane protein TMEM16A is required for normal development of the murine trachea
    • Rock JR, Futtner CR, Harfe BD. The transmembrane protein TMEM16A is required for normal development of the murine trachea. Dev Biol 321: 141-149, 2008.
    • (2008) Dev Biol , vol.321 , pp. 141-149
    • Rock, J.R.1    Futtner, C.R.2    Harfe, B.D.3
  • 183
    • 36048993202 scopus 로고    scopus 로고
    • Identification of genes expressed in the mouse limb using a novel ZPA microarray approach
    • Rock JR, Lopez MC, Baker HV, Harfe BD. Identification of genes expressed in the mouse limb using a novel ZPA microarray approach. Gene Expr Patterns 8: 19-26, 2007.
    • (2007) Gene Expr Patterns , vol.8 , pp. 19-26
    • Rock, J.R.1    Lopez, M.C.2    Baker, H.V.3    Harfe, B.D.4
  • 185
    • 36749077948 scopus 로고    scopus 로고
    • Physiology of airway mucus secretion and pathophysiology of hypersecretion
    • Rogers DF. Physiology of airway mucus secretion and pathophysiology of hypersecretion. Respir Care 52: 1134-1146, 2007.
    • (2007) Respir Care , vol.52 , pp. 1134-1146
    • Rogers, D.F.1
  • 189
    • 78049477615 scopus 로고    scopus 로고
    • Calcium concentration jumps reveal dynamic ion selectivity of calcium-activated chloride currents in mouse olfactory sensory neurons and TMEM16b-transfected HEK 293T cells
    • Sagheddu C, Boccaccio A, Dibattista M, Montani G, Tirindelli R, Menini A. Calcium concentration jumps reveal dynamic ion selectivity of calcium-activated chloride currents in mouse olfactory sensory neurons and TMEM16b-transfected HEK 293T cells. J Physiol 588: 4189-4204, 2010.
    • (2010) J Physiol , vol.588 , pp. 4189-4204
    • Sagheddu, C.1    Boccaccio, A.2    Dibattista, M.3    Montani, G.4    Tirindelli, R.5    Menini, A.6
  • 191
    • 10644262261 scopus 로고    scopus 로고
    • Activation of chloride currents in murine portal vein smooth muscle cells by membrane depolarization involves intracellular calcium release
    • Saleh SN, Greenwood IA. Activation of chloride currents in murine portal vein smooth muscle cells by membrane depolarization involves intracellular calcium release. Am J Physiol Cell Physiol 288: C122-C131, 2005.
    • (2005) Am J Physiol Cell Physiol , vol.288
    • Saleh, S.N.1    Greenwood, I.A.2
  • 192
    • 84856200905 scopus 로고    scopus 로고
    • 2+-activated chloride channel anoctamin 1 in the urethra and its role in excitatory neurotransmission
    • 2+-activated chloride channel anoctamin 1 in the urethra and its role in excitatory neurotransmission. Am J Physiol Renal Physiol 302: F390-F400, 2012.
    • (2012) Am J Physiol Renal Physiol , vol.302
    • Sancho, M.1    García-Pascual, A.2    Triguero, D.3
  • 193
    • 0031918820 scopus 로고    scopus 로고
    • Transduction mechanisms in vertebrate olfactory receptor cells
    • Schild D, Restrepo D. Transduction mechanisms in vertebrate olfactory receptor cells. Physiol Rev 78: 429-466, 1998.
    • (1998) Physiol Rev , vol.78 , pp. 429-466
    • Schild, D.1    Restrepo, D.2
  • 195
    • 51549120559 scopus 로고    scopus 로고
    • Expression cloning of TMEM16A as a calcium-activated chloride channel subunit
    • Schroeder BC, Cheng T, Jan YN, Jan LY. Expression cloning of TMEM16A as a calcium-activated chloride channel subunit. Cell 134: 1019-1029, 2008.
    • (2008) Cell , vol.134 , pp. 1019-1029
    • Schroeder, B.C.1    Cheng, T.2    Jan, Y.N.3    Jan, L.Y.4
  • 197
    • 1642419571 scopus 로고    scopus 로고
    • Direct block of the cystic fibrosis transmembrane conductance regulator Cl-channel by niflumic acid
    • Scott-Ward TS, Li H, Schmidt A, Cai Z, Sheppard DN. Direct block of the cystic fibrosis transmembrane conductance regulator Cl-channel by niflumic acid. Mol Membr Biol 21: 27-38, 2004.
    • (2004) Mol Membr Biol , vol.21 , pp. 27-38
    • Scott-Ward, T.S.1    Li, H.2    Schmidt, A.3    Cai, Z.4    Sheppard, D.N.5
  • 199
    • 84878390836 scopus 로고    scopus 로고
    • TMEM16A-TMEM16B chimaeras to investigate the structure-function relationship of calcium-activated chloride channels
    • Scudieri P, Sondo E, Caci E, Ravazzolo R, Galietta LJ. TMEM16A-TMEM16B chimaeras to investigate the structure-function relationship of calcium-activated chloride channels. Biochem J 452: 443-455, 2013.
    • (2013) Biochem J , vol.452 , pp. 443-455
    • Scudieri, P.1    Sondo, E.2    Caci, E.3    Ravazzolo, R.4    Galietta, L.J.5
  • 200
    • 82755163551 scopus 로고    scopus 로고
    • Constitutive exposure of phosphatidylserine on viable cells
    • Segawa K, Suzuki J, Nagata S. Constitutive exposure of phosphatidylserine on viable cells. Proc Natl Acad Sci USA 108: 19246-19251, 2011.
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 19246-19251
    • Segawa, K.1    Suzuki, J.2    Nagata, S.3
  • 206
    • 77954777804 scopus 로고    scopus 로고
    • Cholesterol depletion alters amplitude and pharmacology of vascular calcium-activated chloride channels
    • Sones WR, Davis AJ, Leblanc N, Greenwood IA. Cholesterol depletion alters amplitude and pharmacology of vascular calcium-activated chloride channels. Cardiovasc Res 87: 476-484, 2010.
    • (2010) Cardiovasc Res , vol.87 , pp. 476-484
    • Sones, W.R.1    Davis, A.J.2    Leblanc, N.3    Greenwood, I.A.4
  • 208
    • 67650866710 scopus 로고    scopus 로고
    • ANO2 is the cilial calcium-activated chloride channel that may mediate olfactory amplification
    • Stephan AB, Shum EY, Hirsh S, Cygnar KD, Reisert J, Zhao H. ANO2 is the cilial calcium-activated chloride channel that may mediate olfactory amplification. Proc Natl Acad Sci USA 106: 11776-11781, 2009.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 11776-11781
    • Stephan, A.B.1    Shum, E.Y.2    Hirsh, S.3    Cygnar, K.D.4    Reisert, J.5    Zhao, H.6
  • 211
    • 0028909037 scopus 로고
    • Evidence against direct activation of chloride secretion by carbachol in the rat distal colon
    • Strabel D, Diener M. Evidence against direct activation of chloride secretion by carbachol in the rat distal colon. Eur J Pharmacol 274: 181-191, 1995.
    • (1995) Eur J Pharmacol , vol.274 , pp. 181-191
    • Strabel, D.1    Diener, M.2
  • 212
    • 33744791766 scopus 로고    scopus 로고
    • Swelling-activated ion channels: Functional regulation in cellswelling, proliferation and apoptosis
    • Stutzin A, Hoffmann EK. Swelling-activated ion channels: functional regulation in cellswelling, proliferation and apoptosis. Acta Physiol 187: 27-42, 2006.
    • (2006) Acta Physiol , vol.187 , pp. 27-42
    • Stutzin, A.1    Hoffmann, E.K.2
  • 213
    • 84864297897 scopus 로고    scopus 로고
    • 2+-activated Cl-channel in pulmonary arterial myocytes: A mechanism contributing to enhanced vasoreactivity
    • 2+-activated Cl-channel in pulmonary arterial myocytes: a mechanism contributing to enhanced vasoreactivity. J Physiol 590: 3507-3521, 2012.
    • (2012) J Physiol , vol.590 , pp. 3507-3521
    • Sun, H.1    Xia, Y.2    Paudel, O.3    Yang, X.R.4    Sham, J.S.5
  • 214
    • 84877709762 scopus 로고    scopus 로고
    • Calcium-dependent phospholipid scramblase activity of TMEM16 protein family members
    • Suzuki J, Fujii T, Imao T, Ishihara K, Kuba H, Nagata S. Calcium-dependent phospholipid scramblase activity of TMEM16 protein family members. J Biol Chem 288: 13305-13316, 2013.
    • (2013) J Biol Chem , vol.288 , pp. 13305-13316
    • Suzuki, J.1    Fujii, T.2    Imao, T.3    Ishihara, K.4    Kuba, H.5    Nagata, S.6
  • 215
    • 78650172970 scopus 로고    scopus 로고
    • Calcium-dependent phospholipid scrambling by TMEM16F
    • Suzuki J, Umeda M, Sims PJ, Nagata S. Calcium-dependent phospholipid scrambling by TMEM16F. Nature 468: 834-838, 2010.
    • (2010) Nature , vol.468 , pp. 834-838
    • Suzuki, J.1    Umeda, M.2    Sims, P.J.3    Nagata, S.4
  • 216
  • 220
    • 12944276875 scopus 로고    scopus 로고
    • Chloride equilibrium potential in salamander cones
    • Thoreson WB, Bryson EJ. Chloride equilibrium potential in salamander cones. BMC Neurosci 5: 53, 2004.
    • (2004) BMC Neurosci , vol.5 , pp. 53
    • Thoreson, W.B.1    Bryson, E.J.2
  • 221
    • 0034014177 scopus 로고    scopus 로고
    • Chloride efflux inhibits single calcium channel open probability in vertebrate photoreceptors: Chloride imaging and cell-attached patch-clamp recordings
    • Thoreson WB, Nitzan R, Miller RF. Chloride efflux inhibits single calcium channel open probability in vertebrate photoreceptors: chloride imaging and cell-attached patch-clamp recordings. Vis Neurosci 17: 197-206, 2000.
    • (2000) Vis Neurosci , vol.17 , pp. 197-206
    • Thoreson, W.B.1    Nitzan, R.2    Miller, R.F.3
  • 225
    • 84876232419 scopus 로고    scopus 로고
    • Identification of a dimerization domain in the TMEM16A calcium-activated chloride channel (CaCC)
    • Tien J, Lee HY, Minor DL Jr, Jan YN, Jan LY. Identification of a dimerization domain in the TMEM16A calcium-activated chloride channel (CaCC). Proc Natl Acad Sci USA 110: 6352-6357, 2013.
    • (2013) Proc Natl Acad Sci USA , vol.110 , pp. 6352-6357
    • Tien, J.1    Lee, H.Y.2    Minor Jr., D.L.3    Jan, Y.N.4    Jan, L.Y.5
  • 226
    • 33745281204 scopus 로고    scopus 로고
    • Heterozygosity for a protein truncation mutation of sodium channel SCN8A in a patient with cerebellar atrophy, ataxia, and mental retardation
    • Trudeau MM, Dalton JC, Day JW, Ranum LP, Meisler MH. Heterozygosity for a protein truncation mutation of sodium channel SCN8A in a patient with cerebellar atrophy, ataxia, and mental retardation. J Med Genet 43: 527-530, 2006.
    • (2006) J Med Genet , vol.43 , pp. 527-530
    • Trudeau, M.M.1    Dalton, J.C.2    Day, J.W.3    Ranum, L.P.4    Meisler, M.H.5
  • 233
    • 84868255280 scopus 로고    scopus 로고
    • Proinflammatory cytokine secretion is suppressed by TMEM16A or CFTR channel activity in human cystic fibrosis bronchial epithelia
    • Veit G, Bossard F, Goepp J, Verkman AS, Galietta LJ, Hanrahan JW, Lukacs GL. Proinflammatory cytokine secretion is suppressed by TMEM16A or CFTR channel activity in human cystic fibrosis bronchial epithelia. Mol Biol Cell 23: 4188-4202, 2012.
    • (2012) Mol Biol Cell , vol.23 , pp. 4188-4202
    • Veit, G.1    Bossard, F.2    Goepp, J.3    Verkman, A.S.4    Galietta, L.J.5    Hanrahan, J.W.6    Lukacs, G.L.7
  • 235
    • 33745120825 scopus 로고    scopus 로고
    • CFTR chloride channel drug discovery: Inhibitors as antidiarrheals and activators for therapy of cystic fibrosis
    • Verkman AS, Lukacs GL, Galietta LJ. CFTR chloride channel drug discovery: inhibitors as antidiarrheals and activators for therapy of cystic fibrosis. Curr Pharm Des 12: 2235-2247, 2006.
    • (2006) Curr Pharm Des , vol.12 , pp. 2235-2247
    • Verkman, A.S.1    Lukacs, G.L.2    Galietta, L.J.3
  • 238
    • 84863150267 scopus 로고    scopus 로고
    • Downregulation of TMEM16A calcium-activated chloride channel contributes to cerebrovascular remodeling during hypertension by promoting basilar smooth muscle cell proliferation
    • Wang M, Yang H, Zheng LY, Zhang Z, Tang YB, Wang GL, Du YH, Lv XF, Liu J, Zhou JG, Guan YY. Downregulation of TMEM16A calcium-activated chloride channel contributes to cerebrovascular remodeling during hypertension by promoting basilar smooth muscle cell proliferation. Circulation 125: 697-707, 2012.
    • (2012) Circulation , vol.125 , pp. 697-707
    • Wang, M.1    Yang, H.2    Zheng, L.Y.3    Zhang, Z.4    Tang, Y.B.5    Wang, G.L.6    Du, Y.H.7    Lv, X.F.8    Liu, J.9    Zhou, J.G.10    Guan, Y.Y.11
  • 239
    • 0027320108 scopus 로고
    • Action of histamine on single smooth muscle cells dispersed from the rabbit pulmonary artery
    • Wang Q, Large WA. Action of histamine on single smooth muscle cells dispersed from the rabbit pulmonary artery. J Physiol 68: 125-139, 1993.
    • (1993) J Physiol , vol.68 , pp. 125-139
    • Wang, Q.1    Large, W.A.2
  • 241
    • 13144268551 scopus 로고    scopus 로고
    • Inactivation of calcium-activated chloride channels in smooth muscle by calcium/calmodulin-dependent protein kinase
    • Wang YX, Kotlikoff MI. Inactivation of calcium-activated chloride channels in smooth muscle by calcium/calmodulin-dependent protein kinase. Proc Natl Acad Sci USA 94: 14918-14923, 1997.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 14918-14923
    • Wang, Y.X.1    Kotlikoff, M.I.2
  • 242
    • 0034820171 scopus 로고    scopus 로고
    • Physiology and pathophysiology of the interstitial cell of Cajal: From bench to bedside. I. Functional development and plasticity of interstitial cells of Cajal networks
    • Ward SM, Sanders KM. Physiology and pathophysiology of the interstitial cell of Cajal: from bench to bedside. I. Functional development and plasticity of interstitial cells of Cajal networks. Am J Physiol Gastrointest Liver Physiol 281: G602-G611, 2001.
    • (2001) Am J Physiol Gastrointest Liver Physiol , vol.281
    • Ward, S.M.1    Sanders, K.M.2
  • 244
    • 0027999286 scopus 로고
    • Scott syndrome: A disorder of platelet coagulant activity
    • Weiss HJ. Scott syndrome: a disorder of platelet coagulant activity. Semin Hematol 31: 312-319, 1994.
    • (1994) Semin Hematol , vol.31 , pp. 312-319
    • Weiss, H.J.1
  • 246
  • 247
    • 84863611406 scopus 로고    scopus 로고
    • Yeast Ist2 recruits the endoplasmic reticulum to the plasma membrane and creates a ribosome-free membrane microcompartment
    • Wolf W, Kilic A, Schrul B, Lorenz H, Schwappach B, Seedorf M. Yeast Ist2 recruits the endoplasmic reticulum to the plasma membrane and creates a ribosome-free membrane microcompartment. PLoS One 7: e39703, 2012.
    • (2012) PLoS One , vol.7
    • Wolf, W.1    Kilic, A.2    Schrul, B.3    Lorenz, H.4    Schwappach, B.5    Seedorf, M.6
  • 248
    • 84887386469 scopus 로고    scopus 로고
    • 2+-activated Cl-channel in Drosophila melanogaster with an unexpected role in host defense
    • 2+-activated Cl-channel in Drosophila melanogaster with an unexpected role in host defense. Elife 2: e00862, 2013.
    • (2013) Elife , vol.2
    • Wong, X.M.1    Younger, S.2    Peters, C.J.3    Jan, Y.N.4    Jan, L.Y.5
  • 250
    • 79957786620 scopus 로고    scopus 로고
    • Voltage-and calciumdependent gating of TMEM16A/Ano1 chloride channels are physically coupled by the first intracellular loop
    • Xiao Q, Yu K, Perez-Cornejo P, Cui Y, Arreola J, Hartzell HC. Voltage-and calciumdependent gating of TMEM16A/Ano1 chloride channels are physically coupled by the first intracellular loop. Proc Natl Acad Sci USA 108: 8891-8896, 2011.
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 8891-8896
    • Xiao, Q.1    Yu, K.2    Perez-Cornejo, P.3    Cui, Y.4    Arreola, J.5    Hartzell, H.C.6
  • 251
    • 0029938944 scopus 로고    scopus 로고
    • Inositol 3,4,5,6-tetrakisphosphate inhibits the calmodulin-dependent protein kinase II-activated chloride conductance in T84 colonic epithelial cells
    • XieW, Kaetzel MA, Bruzik KS, Dedman JR, Shears SB, Nelson DJ. Inositol 3,4,5,6-tetrakisphosphate inhibits the calmodulin-dependent protein kinase II-activated chloride conductance in T84 colonic epithelial cells. J Biol Chem 271: 14092-14097, 1996.
    • (1996) J Biol Chem , vol.271 , pp. 14092-14097
    • Xie, W.1    Kaetzel, M.A.2    Bruzik, K.S.3    Dedman, J.R.4    Shears, S.B.5    Nelson, D.J.6
  • 253
    • 52649145895 scopus 로고    scopus 로고
    • GPS 2.0, a tool to predict kinase-specific phosphorylation sites in hierarchy
    • Xue Y, Ren J, Gao X, Jin C, Wen L, Yao X. GPS 2.0, a tool to predict kinase-specific phosphorylation sites in hierarchy. Mol Cell Proteomics 7: 1598-1608, 2008.
    • (2008) Mol Cell Proteomics , vol.7 , pp. 1598-1608
    • Xue, Y.1    Ren, J.2    Gao, X.3    Jin, C.4    Wen, L.5    Yao, X.6
  • 254
    • 73549101684 scopus 로고    scopus 로고
    • Calcium-activated chloride current amplifies the response to urine in mouse vomeronasal sensory neurons
    • Yang C, Delay RJ. Calcium-activated chloride current amplifies the response to urine in mouse vomeronasal sensory neurons. J Gen Physiol 135: 3-13, 2010.
    • (2010) J Gen Physiol , vol.135 , pp. 3-13
    • Yang, C.1    Delay, R.J.2
  • 259
    • 84859435658 scopus 로고    scopus 로고
    • Explaining calcium-dependent gating of anoctamin-1 chloride channels requires a revised topology
    • Yu K, Duran C, Qu Z, Cui YY, Hartzell HC. Explaining calcium-dependent gating of anoctamin-1 chloride channels requires a revised topology. Circ Res 110: 990-999, 2012.
    • (2012) Circ Res , vol.110 , pp. 990-999
    • Yu, K.1    Duran, C.2    Qu, Z.3    Cui, Y.Y.4    Hartzell, H.C.5
  • 260
    • 84888307456 scopus 로고    scopus 로고
    • Divalent cations modulate TMEM16A calcium-activated chloride channels by a common mechanism
    • Yuan H, Gao C, Chen Y, Jia M, Geng J, Zhang H, Zhan Y, Boland LM, An H. Divalent cations modulate TMEM16A calcium-activated chloride channels by a common mechanism. J Membr Biol 246: 893-902, 2013.
    • (2013) J Membr Biol , vol.246 , pp. 893-902
    • Yuan, H.1    Gao, C.2    Chen, Y.3    Jia, M.4    Geng, J.5    Zhang, H.6    Zhan, Y.7    Boland, L.M.8    An, H.9
  • 262
    • 0030995528 scopus 로고    scopus 로고
    • Role of calcium-activated chloride current in regulating pulmonary vasomotor tone
    • Yuan XJ. Role of calcium-activated chloride current in regulating pulmonary vasomotor tone. Am J Physiol Lung Cell Mol Physiol 272: L959-L968, 1997.
    • (1997) Am J Physiol Lung Cell Mol Physiol , vol.272
    • Yuan, X.J.1
  • 264
    • 0034192747 scopus 로고    scopus 로고
    • Direct comparison of NPPB and DPC as probes of CFTR expressed in Xenopus oocytes
    • Zhang ZR, Zeltwanger S, McCarty NA. Direct comparison of NPPB and DPC as probes of CFTR expressed in Xenopus oocytes. J Membr Biol 175: 35-52, 2000.
    • (2000) J Membr Biol , vol.175 , pp. 35-52
    • Zhang, Z.R.1    Zeltwanger, S.2    McCarty, N.A.3
  • 265
    • 0036624776 scopus 로고    scopus 로고
    • Normal hemostasis but defective hematopoietic response to growth factors in mice deficient in phospholipid scramblase 1
    • Zhou Q, Zhao J, Wiedmer T, Sims PJ. Normal hemostasis but defective hematopoietic response to growth factors in mice deficient in phospholipid scramblase 1. Blood 99: 4030-4038, 2002.
    • (2002) Blood , vol.99 , pp. 4030-4038
    • Zhou, Q.1    Zhao, J.2    Wiedmer, T.3    Sims, P.J.4
  • 266
    • 70350680125 scopus 로고    scopus 로고
    • 2+-activated Cl-conductance in interstitial cells of Cajal linked to slow wave currents and pacemaker activity
    • 2+-activated Cl-conductance in interstitial cells of Cajal linked to slow wave currents and pacemaker activity. J Physiol 587: 4905-4918, 2009.
    • (2009) J Physiol , vol.587 , pp. 4905-4918
    • Zhu, M.H.1    Kim, T.W.2    Ro, S.3    Yan, W.4    Ward, S.M.5    Koh, S.D.6    Sanders, K.M.7
  • 267
    • 2942637935 scopus 로고    scopus 로고
    • Scott syndrome, a bleeding disorder caused by defective scrambling of membrane phospholipids
    • Zwaal RF, Comfurius P, Bevers EM. Scott syndrome, a bleeding disorder caused by defective scrambling of membrane phospholipids. Biochim Biophys Acta 1636: 119-28, 2004.
    • (2004) Biochim Biophys Acta , vol.1636 , pp. 119-128
    • Zwaal, R.F.1    Comfurius, P.2    Bevers, E.M.3
  • 268
    • 0031043059 scopus 로고    scopus 로고
    • Pathophysiologic implications of membrane phospholipid asymmetry in blood cells
    • Zwaal RF, Schroit AJ. Pathophysiologic implications of membrane phospholipid asymmetry in blood cells. Blood 89: 1121-1132, 1997.
    • (1997) Blood , vol.89 , pp. 1121-1132
    • Zwaal, R.F.1    Schroit, A.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.