Novel role for pendrin in orchestrating bicarbonate secretion in cystic fibrosis transmembrane conductance regulator (CFTR)-expressing airway serous cells

Journal of Biological Chemistry

Volumn 286, Issue 47, 2011, Pages 41069-41082

  Garnett, James P ^a,f   Hickman, Emma ^b   Burrows, Rachel ^b   Hegyi, Péter ^c   Tiszlavicz, László ^c   Cuthbert, Alan W ^d   Fong, Peying ^e   Gray, Michael A ^a  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

^b NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH   (United States)

^c UNIVERSITY OF SZEGED   (Hungary)

^d UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^e KANSAS STATE UNIVERSITY   (United States)

^f ST GEORGE'S UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANION EXCHANGE; ANION EXCHANGERS; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATORS; EPITHELIAL TISSUE; INTRACELLULAR PH; NORMAL TISSUE; QUANTITATIVE RT-PCR; REAL TIME MEASUREMENTS; WESTERN BLOTS; WILD TYPES;

CELL CULTURE; CELLS; ION EXCHANGE RESINS; IONS; PH EFFECTS; PHYSIOLOGY; PROTEINS; TISSUE;

LIQUIDS;

BICARBONATE CHLORIDE ANTIPORTER; CHLORIDE ION; CYCLIC AMP DEPENDENT PROTEIN KINASE; PENDRIN; SHORT HAIRPIN RNA; TRANSMEMBRANE CONDUCTANCE REGULATOR;

ANIMAL CELL; ANION EXCHANGE; ARTICLE; CELL CULTURE; CELL PH; CELL POLARITY; CELL STRAIN; CELL STRAIN CALU 3; CONTROLLED STUDY; EPITHELIUM CELL; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN SECRETION; PROTEIN TRANSPORT; RAT; RESPIRATORY EPITHELIUM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSCYTOSIS; WESTERN BLOTTING; WILD TYPE;

ANIMALS; BICARBONATES; BODY FLUIDS; CELL LINE, TUMOR; CHLORIDE-BICARBONATE ANTIPORTERS; CHLORIDES; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; EPITHELIAL CELLS; GENE EXPRESSION REGULATION; GENE KNOCKDOWN TECHNIQUES; HUMANS; HYDROGEN-ION CONCENTRATION; MEMBRANE TRANSPORT PROTEINS; RATS; RESPIRATORY SYSTEM; THYROID GLAND;

EID: 81755189072     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.266734     Document Type: Article

References (70)

1. Coakley, R. D., Grubb, B. R., Paradiso, A. M., Gatzy, J. T., Johnson, L. G., Kreda, S. M., O'Neal, W. K., and Boucher, R. C. (2003) Proc. Natl. Acad. Sci. U.S.A. 100, 16083-16088
2. Song, Y., Salinas, D., Nielson, D. W., and Verkman, A. S. (2006) Am. J. Physiol. Cell. Physiol. 290, C741-C749
3. Quinton, P. M. (2008) Lancet 372, 415-417
4. Garcia, M. A., Yang, N., and Quinton, P. M. (2009) J. Clin. Invest. 119, 2613-2622
5. Holma, B., and Hegg, P. O. (1989) Sci. Total Environ. 84, 71-82
6. Quinton, P. M. (2001) Nat. Med. 7, 292-293
7. Chen, E. Y., Yang, N., Quinton, P. M., and Chin, W. C. (2010) Am. J. Physiol. Lung Cell Mol. Physiol. 299, L542-L549
8. Muchekehu, R. W., and Quinton, P. M. (2010) J. Physiol. 588, 2329-2342
9. Clary-Meinesz, C., Mouroux, J., Cosson, J., Huitorel, P., and Blaive, B. (1998) Eur. Respir. J. 11, 330-333
10. Allen, D. B., Maguire, J. J., Mahdavian, M., Wicke, C., Marcocci, L., Scheuenstuhl, H., Chang, M., Le, A. X., Hopf, H. W., and Hunt, T. K. (1997) Arch. Surg. 132, 991-996
11. Simchowitz, L. (1985) J. Clin. Invest. 76, 1079-1089
12. Ostedgaard, L. S., Meyerholz, D. K., Chen, J. H., Pezzulo, A. A., Karp, P. H., Rokhlina, T., Ernst, S. E., Hanfland, R. A., Reznikov, L. R., Ludwig, P. S., Rogan, M. P., Davis, G. J., Dohrn, C. L., Wohlford-Lenane, C., Taft, P. J., Rector, M. V., Hornick, E., Nassar, B. S., Samuel, M., Zhang, Y., Richter, S. S., Uc, A., Shilyansky, J., Prather, R. S., McCray, P. B., Jr., Zabner, J., Welsh, M. J., and Stoltz, D. A. (2011) Sci. Transl. Med. 3, 74ra24
13. Smith, J. J., and Welsh, M. J. (1992) J. Clin. Invest. 89, 1148-1153
14. Choi, J. Y., Khansaheb, M., Joo, N. S., Krouse, M. E., Robbins, R. C., Weill, D., and Wine, J. J. (2009) J. Clin. Invest. 119, 1189-1200
15. Khansaheb, M., Choi, J. Y., Joo, N. S., Yang, Y. M., Krouse, M., and Wine, J. J. (2011) Am. J. Physiol. Lung Cell Mol. Physiol. 300, L370-L379
16. Wine, J. J., and Joo, N. S. (2004) Proc. Am. Thorac. Soc. 1, 47-53
17. Devor, D. C., Singh, A. K., Lambert, L. C., DeLuca, A., Frizzell, R. A., and Bridges, R. J. (1999) J. Gen. Physiol. 113, 743-760
18. Illek, B., Yankaskas, J. R., and Machen, T. E. (1997) Am. J. Physiol. 272, L752-L761
19. Krouse, M. E., Talbott, J. F., Lee, M. M., Joo, N. S., and Wine, J. J. (2004) Am. J. Physiol. Lung Cell Mol. Physiol. 287, L1274-L1283
20. Stewart, A. K., Yamamoto, A., Nakakuki, M., Kondo, T., Alper, S. L., and Ishiguro, H. (2009) Am. J. Physiol. Gastrointest. Liver Physiol. 296, G1307-G1317
21. Melvin, J. E., Yule, D., Shuttleworth, T., and Begenisich, T. (2005) Annu. Rev. Physiol. 67, 445-469
22. Singh, A. K., Riederer, B., Chen, M., Xiao, F., Krabbenhöft, A., Engelhardt, R., Nylander, O., Soleimani, M., and Seidler, U. (2010) Am. J. Physiol. Cell Physiol. 298, C1057-C1065
23. Chen, W. Y., Xu, W. M., Chen, Z. H., Ni, Y., Yuan, Y. Y., Zhou, S. C., Zhou, W. W., Tsang, L. L., Chung, Y. W., Höglund, P., Chan, H. C., and Shi, Q. X. (2009) Biol. Reprod. 80, 115-123
24. Ko, S. B., Zeng, W., Dorwart, M. R., Luo, X., Kim, K. H., Millen, L., Goto, H., Naruse, S., Soyombo, A., Thomas, P. J., and Muallem, S. (2004) Nat. Cell Biol. 6, 343-350
25. Wheat, V. J., Shumaker, H., Burnham, C., Shull, G. E., Yankaskas, J. R., and Soleimani, M. (2000) Am. J. Physiol. Cell Physiol. 279, C62-C71
26. Lohi, H., Kujala, M., Makela, S., Lehtonen, E., Kestila, M., Saarialho-Kere, U., Markovich, D., and Kere, J. (2002) J. Biol. Chem. 277, 14246-14254
27. Bertrand, C. A., Zhang, R., Pilewski, J. M., and Frizzell, R. A. (2009) J. Gen. Physiol. 133, 421-438
28. Shen, B. Q., Finkbeiner, W. E., Wine, J. J., Mrsny, R. J., and Widdicombe, J. H. (1994) Am. J. Physiol. 266, L493-L501
29. MacVinish, L. J., Cope, G., Ropenga, A., and Cuthbert, A. W. (2007) Br. J. Pharmacol. 150, 1055-1065
30. Pedemonte, N., Caci, E., Sondo, E., Caputo, A., Rhoden, K., Pfeffer, U., Di Candia, M., Bandettini, R., Ravazzolo, R., Zegarra-Moran, O., and Galietta, L. J. V. (2007) J. Immunol. 178, 5144-5153
31. Rakonczay, Z., Jr., Hegyi, P., Hasegawa, M., Inoue, M., You, J., Iida, A., Ignáth, I., Alton, E. W., Griesenbach, U., Ovári, G., Vág, J., Da Paula, A. C., Crawford, R. M., Varga, G., Amaral, M. D., Mehta, A., Lonovics, J., Argent, B. E., and Gray, M. A. (2008) J. Cell. Physiol. 214, 442-455
32. Inglis, S. K., Finlay, L., Ramminger, S. J., Richard, K., Ward, M. R., Wilson, S. M., and Olver, R. E. (2002) J. Physiol. 538, 527-539
33. Loffing, J., Moyer, B. D., Reynolds, D., Shmukler, B. E., Alper, S. L., and Stanton, B. A. (2000) Am. J. Physiol. Cell Physiol. 279, C1016-C1023
34. Dérand, R., Montoni, A., Bulteau-Pignoux, L., Janet, T., Moreau, B., Muller, J. M., and Becq, F. (2004) Br. J. Pharmacol. 141, 698-708
35. Cobb, B. R., Ruiz, F., King, C. M., Fortenberry, J., Greer, H., Kovacs, T., Sorscher, E. J., and Clancy, J. P. (2002) Am. J. Physiol. Lung Cell Mol. Physiol. 282, L12-L25
36. Dorwart, M. R., Shcheynikov, N., Yang, D., and Muallem, S. (2008) Physiology 23, 104-114
37. Dossena, S., Vezzoli, V., Cerutti, N., Bazzini, C., Tosco, M., Sironi, C., Rodighiero, S., Meyer, G., Fascio, U., Fürst, J., Ritter, M., Fugazzola, L., Persani, L., Zorowka, P., Storelli, C., Beck-Peccoz, P., Bottà, G., and Paulmichl, M. (2006) Cell. Physiol. Biochem. 17, 245-256
38. Mount, D. B., and Romero, M. F. (2004) Pflugers Arch. 447, 710-721
39. Scott, D. A., Wang, R., Kreman, T. M., Sheffield, V. C., and Karniski, L. P. (1999) Nat. Genet. 21, 440-443
40. Shcheynikov, N., Yang, D., Wang, Y., Zeng, W., Karniski, L. P., So, I., Wall, S. M., and Muallem, S. (2008) J. Physiol. 586, 3813-3824
41. Royaux, I. E., Suzuki, K., Mori, A., Katoh, R., Everett, L. A., Kohn, L. D., and Green, E. D. (2000) Endocrinology 141, 839-845
42. Nakao, I., Kanaji, S., Ohta, S., Matsushita, H., Arima, K., Yuyama, N., Yamaya, M., Nakayama, K., Kubo, H., Watanabe, M., Sagara, H., Sugiyama, K., Tanaka, H., Toda, S., Hayashi, H., Inoue, H., Hoshino, T., Shiraki, A., Inoue, M., Suzuki, K., Aizawa, H., Okinami, S., Nagai, H., Hasegawa, M., Fukuda, T., Green, E. D., and Izuhara, K. (2008) J. Immunol. 180, 6262-6269
43. Satoh, H., Susaki, M., Shukunami, C., Iyama, K., Negoro, T., and Hiraki, Y. (1998) J. Biol. Chem. 273, 12307-12315
44. Shcheynikov, N., Wang, Y., Park, M., Ko, S. B., Dorwart, M., Naruse, S., Thomas, P. J., and Muallem, S. (2006) J. Gen. Physiol. 127, 511-524
45. Scott, D. A., and Karniski, L. P. (2000) Am. J. Physiol. Cell Physiol. 278, C207-C211
46. Lee, M. C., Penland, C. M., Widdicombe, J. H., and Wine, J. J. (1998) Am. J. Physiol. 274, L450-L453
47. Thiagarajah, J. R., Song, Y., Haggie, P. M., and Verkman, A. S. (2004) FASEB J. 18, 875-877
48. Ko, S. B., Shcheynikov, N., Choi, J. Y., Luo, X., Ishibashi, K., Thomas, P. J., Kim, J. Y., Kim, K. H., Lee, M. G., Naruse, S., and Muallem, S. (2002)EMBO J. 21, 5662-5672
49. Chang, M. H., Plata, C., Sindic, A., Ranatunga, W. K., Chen, A. P., Zandi-Nejad, K., Chan, K. W., Thompson, J., Mount, D. B., and Romero, M. F. (2009) J. Biol. Chem. 284, 28306-28318
50. Ishiguro, H., Naruse, S., Kitagawa, M., Mabuchi, T., Kondo, T., Hayakawa, T., Case, R. M., and Steward, M. C. (2002) J. Physiol. 539, 175-189
51. Stewart, A. K., Kurschat, C. E., Burns, D., Banger, N., Vaughan-Jones, R. D., and Alper, S. L. (2007) Am. J. Physiol. Cell Physiol. 292, C909-C918
52. Lee, R. J., and Foskett, J. K. (2010) J. Clin. Invest. 120, 3137-3148
53. Simpson, J. E., Gawenis, L. R., Walker, N. M., Boyle, K. T., and Clarke, L. L. (2005) Am. J. Physiol. Gastrointest. Liver Physiol. 288, G1241-G1251
54. Ramesh Babu, P. B., Chidekel, A., Utidjian, L., and Shaffer, T. H. (2004) Biochem. Biophys. Res. Commun. 319, 1132-1137
55. Irokawa, T., Krouse, M. E., Joo, N. S., Wu, J. V., and Wine, J. J. (2004) Am. J. Physiol. Lung Cell Mol. Physiol. 287, L784-L793
56. Joo, N. S., Saenz, Y., Krouse, M. E., and Wine, J. J. (2002) J. Biol. Chem. 277, 28167-28175
57. Ballard, S. T., and Inglis, S. K. (2004) J. Physiol. 556, 1-10
58. Sohma, Y., Gray, M. A., Imai, Y., and Argent, B. E. (2000) J. Membr. Biol. 176, 77-100
59. Ballard, S. T., Trout, L., Bebök, Z., Sorscher, E. J., and Crews, A. (1999) Am. J. Physiol. 277, L694-L699
60. Cho, H. J., Joo, N. S., and Wine, J. J. (2010) Am. J. Physiol. Lung Cell Mol. Physiol. 299, L124-L136
61. Joo, N. S., Cho, H. J., Khansaheb, M., and Wine, J. J. (2010) J. Clin. Invest. 120, 3161-3166
62. Engelhardt, J. F., Yankaskas, J. R., Ernst, S. A., Yang, Y., Marino, C. R., Boucher, R. C., Cohn, J. A., and Wilson, J. M. (1992) Nat. Genet. 2, 240-248
63. Ma, T., Thiagarajah, J. R., Yang, H., Sonawane, N. D., Folli, C., Galietta, L. J., and Verkman, A. S. (2002) J. Clin. Invest. 110, 1651-1658
64. Schmid, A., Sutto, Z., Schmid, N., Novak, L., Ivonnet, P., Horvath, G., Conner, G., Fregien, N., and Salathe, M. (2010) J. Biol. Chem. 285, 29998-30007
65. Matsui, H., Grubb, B. R., Tarran, R., Randell, S. H., Gatzy, J. T., Davis, C. W., and Boucher, R. C. (1998) Cell 95, 1005-1015
66. Bhaskar, K. R., Gong, D. H., Bansil, R., Pajevic, S., Hamilton, J. A., Turner, B. S., and LaMont, J. T. (1991) Am. J. Physiol. 261, G827-G832
67. Everett, L. A., Glaser, B., Beck, J. C., Idol, J. R., Buchs, A., Heyman, M., Adawi, F., Hazani, E., Nassir, E., Baxevanis, A. D., Sheffield, V. C., and Green, E. D. (1997) Nat. Genet. 17, 411-422
68. Everett, L. A., Morsli, H., Wu, D. K., and Green, E. D. (1999) Proc. Natl. Acad. Sci. U.S.A. 96, 9727-9732
69. Royaux, I. E., Wall, S. M., Karniski, L. P., Everett, L. A., Suzuki, K., Knepper, M. A., and Green, E. D. (2001) Proc. Natl. Acad. Sci. U.S.A. 98, 4221-4226
70. Wall, S. M., and Pech, V. (2008) Curr. Opin. Nephrol. Hypertens. 17, 18-24