Mapping the BKCa Channel's "Ca2+ Bowl": Side-chains Essential for Ca2+ Sensing

Journal of General Physiology

Volumn 123, Issue 5, 2004, Pages 475-489

  Bao, Lin ^a   Kaldany, Christina ^a   Holmstrand, Ericka C ^a   Cox, Daniel H ^a,b  

^a TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b TUFTS MEDICAL CENTER   (United States)

Author keywords

BKCa; Ca 2+ binding; Ca2+ bowl; mSlo; Potassium channel

Indexed keywords

ALANINE; ASPARTIC ACID; CALCIUM 45; CALCIUM ACTIVATED POTASSIUM CHANNEL; CALCIUM ION; COMPLEMENTARY RNA; GLUTATHIONE TRANSFERASE; HYBRID PROTEIN; MUTANT PROTEIN; POTASSIUM CHANNEL; POTASSIUM ION; VOLTAGE GATED POTASSIUM CHANNEL; CALCIUM; LARGE CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNEL; RECOMBINANT PROTEIN;

ANIMAL CELL; ARTICLE; BINDING SITE; CONTROLLED STUDY; MEMBRANE CONDUCTANCE; MOLECULAR MODEL; MUTAGENESIS; NONHUMAN; OOCYTE; PATCH CLAMP; XENOPUS LAEVIS; AMINO ACID SEQUENCE; ANIMAL; CALCIUM SIGNALING; CELL CULTURE; CELL MEMBRANE POTENTIAL; CHANNEL GATING; CHEMICAL STRUCTURE; CHEMISTRY; COMPUTER SIMULATION; METABOLISM; MOLECULAR GENETICS; MUTATION; PHYSIOLOGY; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN TERTIARY STRUCTURE; SIGNAL TRANSDUCTION; SITE DIRECTED MUTAGENESIS; STRUCTURE ACTIVITY RELATION;

AMINO ACID SEQUENCE; ANIMALS; CALCIUM; CALCIUM SIGNALING; CELLS, CULTURED; COMPUTER SIMULATION; ION CHANNEL GATING; LARGE-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELS; MEMBRANE POTENTIALS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; MUTATION; OOCYTES; POTASSIUM CHANNELS, CALCIUM-ACTIVATED; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; SIGNAL TRANSDUCTION; STRUCTURE-ACTIVITY RELATIONSHIP; XENOPUS LAEVIS;

EID: 2342481193     PISSN: 00221295     EISSN: None     Source Type: Journal    
DOI: 10.1085/jgp.200409052     Document Type: Article

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