Inactivation of anoctamin-6/Tmem16f, a regulator of phosphatidylserine scrambling in osteoblasts, leads to decreased mineral deposition in skeletal tissues

Journal of Bone and Mineral Research

Volumn 28, Issue 2, 2013, Pages 246-259

  Ehlen, Harald W A ^a   Chinenkova, Milana ^a   Moser, Markus ^b   Munter, Hans Markus ^c   Krause, Yvonne ^a   Gross, Stefanie ^a   Brachvogel, Bent ^d   Wuelling, Manuela ^a   Kornak, Uwe ^c,e   Vortkamp, Andrea ^a,c  

^a UNIVERSITY OF DUISBURG ESSEN   (Germany)

^b MAX PLANCK INSTITUTE OF BIOCHEMISTRY   (Germany)

^c MAX PLANCK INSTITUTE FOR MOLECULAR GENETICS   (Germany)

^d UNIVERSITY OF COLOGNE   (Germany)

^e CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

anoctamin; mineralization; osteoblast; phospholipid scrambling; Skeletal development

Indexed keywords

ANOCTAMIN 6; MEMBRANE PROTEIN; MESSENGER RNA; PHOSPHATIDYLSERINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BONE DEVELOPMENT; CARTILAGE CELL; CELL DIFFERENTIATION; CHEMICAL PARAMETERS; CONTROLLED STUDY; GENE DELETION; HISTOPATHOLOGY; IN SITU HYBRIDIZATION; MINERAL DEPOSITION; MINERALIZATION; MORPHOMETRICS; MOUSE; MUTANT; NONHUMAN; OSTEOBLAST; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SKELETAL MUSCLE; SKELETON MALFORMATION;

ANIMALS; ANIMALS, NEWBORN; BIOLOGICAL TRANSPORT; BONE AND BONES; CALCIFICATION, PHYSIOLOGIC; CELLS, CULTURED; EMBRYO, MAMMALIAN; MICE; MICE, MUTANT STRAINS; OSTEOBLASTS; PHENOTYPE; PHOSPHATIDYLSERINES; PHOSPHOLIPID TRANSFER PROTEINS; SKULL;

EID: 84872471468     PISSN: 08840431     EISSN: 15234681     Source Type: Journal    
DOI: 10.1002/jbmr.1751     Document Type: Article

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