Dynamic modulation of ANO1/TMEM16A HCO3- permeability by Ca2+/calmodulin

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 1, 2013, Pages 360-365

  Jung, Jinsei ^a   Nam, Joo Hyun ^b   Park, Hyun Woo ^a   Oh, Uhtaek ^c   Yoon, Joo Heon ^a   Lee, Min Goo ^a  

^a Yonsei University College of Medicine   (South Korea)

^b Dongguk University College of Medicine   (South Korea)

^c Seoul National University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ANOCTAMIN 1; CALCIUM; CALMODULIN; MEMBRANE PROTEIN; UNCLASSIFIED DRUG;

ACINAR CELL; ANIMAL CELL; ANION TRANSPORT; ARTICLE; CELL LINE; CELL PERMEABILIZATION; CONTROLLED STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN MOTIF; PROTEIN PROTEIN INTERACTION; SALIVARY GLAND; SECRETION (PROCESS); SUBMANDIBULAR GLAND;

ACINAR CELLS; ANIMALS; BICARBONATES; CALCIUM; CALMODULIN; CELL MEMBRANE PERMEABILITY; CHLORIDE CHANNELS; EPITHELIAL CELLS; HEK293 CELLS; HUMANS; IMMUNOBLOTTING; MICE; PATCH-CLAMP TECHNIQUES; REAL-TIME POLYMERASE CHAIN REACTION; SUBMANDIBULAR GLAND;

EID: 84871959313     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1211594110     Document Type: Article

References (37)

1. Hartzell C, Putzier I, Arreola J (2005) Calcium-activated chloride channels. Annu Rev Physiol 67:719- 758.
2. - channel in mouse submandibular salivary gland acinar cells. J Biol Chem 285(17):12990-13001.
3. Yang YD, et al. (2008) TMEM16A confers receptor-activated calcium-dependent chloride conductance. Nature 455(7217):1210-1215.
4. Caputo A, et al. (2008) TMEM16A, a membrane protein associated with calcium-dependent chloride channel activity. Science 322(5901):590-594.
5. Schroeder BC, Cheng T, Jan YN, Jan LY (2008) Expression cloning of TMEM16A as a calcium-activated chloride channel subunit. Cell 134(6):1019-1029.
6. Stephan AB, et al. (2009) ANO2 is the cilial calcium-activated chloride channel that may mediate olfactory amplification. Proc Natl Acad Sci USA 106(28):11776-11781.
7. - channels. J Gen Physiol 116(6):825-844.
8. Ishiguro H, et al. (2009) CFTR functions as a bicarbonate channel in pancreatic duct cells. J Gen Physiol 133(3):315-326.
9. - transport in a mathematical model of the pancreatic ductal epithelium. J Membr Biol 176(1):77-100.
10. Wang XF, et al. (2003) Involvement of CFTR in uterine bicarbonate secretion and the fertilizing capacity of sperm. Nat Cell Biol 5(10):902-906.
11. 3 secretion. Physiol Rev 92(1):39-74.
12. Hatefi Y, Hanstein WG (1969) Solubilization of particulate proteins and nonelectrolytes by chaotropic agents. Proc Natl Acad Sci USA 62(4):1129-1136.
13. Quinton PM (2008) Cystic fibrosis: Impaired bicarbonate secretion and mucoviscidosis. Lancet 372(9636):415- 417.
14. Gee HY, Noh SH, Tang BL, Kim KH, Lee MG (2011) Rescue of ΔF508-CFTR trafficking via a GRASP-dependent unconventional secretion pathway. Cell 146(5):746-760.
15. Evans MG, Marty A (1986) Calcium-dependent chloride currents in isolated cells from rat lacrimal glands. J Physiol 378:437-460.
16. Nilius B, et al. (1997) Kinetic and pharmacological properties of the calcium-activated chloride-current in macrovascular endothelial cells. Cell Calcium 22(1):53- 63.
17. 2+ signals. J Gen Physiol 115(1):59-80.
18. Namkung W, Phuan PW, Verkman AS (2011) TMEM16A inhibitors reveal TMEM16A as a minor component of calcium-activated chloride channel conductance in airway and intestinal epithelial cells. J Biol Chem 286(3):2365-2374.
19. i and its role in pancreatic bicarbonate secretion. Gastroenterology 139(2):620-631.
20. Smith SS, Steinle ED, Meyerhoff ME, Dawson DC (1999) Cystic fibrosis transmembrane conductance regulator. Physical basis for lyotropic anion selectivity patterns. J Gen Physiol 114(6):799-818.
21. Born M (1920) Volumen un hydrationwärme der ionen. Z Phys 1(1):45-48.
22. Suh BC, Hille B (2008) PIP2 is a necessary cofactor for ion channel function: How and why? Annu Rev Biophys 37:175-195.
23. Ohya Y, Botstein D (1994) Diverse essential functions revealed by complementing yeast calmodulin mutants. Science 263(5149):963-966.
24. Rhoads AR, Friedberg F (1997) Sequence motifs for calmodulin recognition. FASEB J 11(5):331-340.
25. Swindells MB, Ikura M (1996) Pre-formation of the semi-open conformation by the apo-calmodulin C-terminal domain and implications binding IQ-motifs. Nat Struct Biol 3(6):501-504.
26. Persechini A, Moncrief ND, Kretsinger RH (1989) The EF-hand family of calcium-modulated proteins. Trends Neurosci 12(11):462-467.
27. Xiao Q, et al. (2011) Voltage- and calcium-dependent gating of TMEM16A/Ano1 chloride channels are physically coupled by the first intracellular loop. Proc Natl Acad Sci USA 108(21):8891-8896.
28. Ferrera L, et al. (2009) Regulation of TMEM16A chloride channel properties by alternative splicing. J Biol Chem 284(48):33360-33368.
29. Tian Y, et al. (2011) Calmodulin-dependent activation of the epithelial calcium-dependent chloride channel TMEM16A. FASEB J 25(3):1058-1068.
30. Sagheddu C, et al. (2010) Calcium concentration jumps reveal dynamic ion selectivity of calcium-activated chloride currents in mouse olfactory sensory neurons and TMEM16b-transfected HEK 293T cells. J Physiol 588(Pt 21):4189-4204.
31. - transport in mucin secretion: Lessons from cystic fibrosis. Am J Physiol Cell Physiol 299(6):C1222-C1233.
32. Thaysen JH, Thorn NA, Schwartz IL (1954) Excretion of sodium, potassium, chloride and carbon dioxide in human parotid saliva. Am J Physiol 178(1):155-159.
33. Zhang GH, Cragoe EJ, Jr., Melvin JE (1992) Regulation of cytoplasmic pH in rat sublingual mucous acini at rest and during muscarinic stimulation. J Membr Biol 129(3):311-321.
34. Neyraud E, Bult JH, Dransfield E (2009) Continuous analysis of parotid saliva during resting and short-duration simulated chewing. Arch Oral Biol 54(5):449-456.
35. i waves. J Biol Chem 272(25):15765-15770.
36. 2+ microdomains. J Cell Sci 123(Pt 18):3201-3208.
37. 3 receptor channel clusters and concentration profiles. Biophys J 86(5):2660-2673.