TMEM16 proteins produce volume-regulated chloride currents that are reduced in mice lacking TMEM16A

Journal of Biological Chemistry

Volumn 284, Issue 42, 2009, Pages 28571-28578

  Almaça, Joana ^a   Tian, Yuemin ^a   Aldehni, Fadi ^a   Ousingsawat, Jiraporn ^a   Kongsuphol, Patthara ^a   Rock, Jason R ^b   Harfe, Brian D ^b   Schreiber, Rainer ^a   Kunzelmann, Karl ^a  

^a UNIVERSITY OF REGENSBURG   (Germany)

^b UNIVERSITY OF FLORIDA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACINAR CELLS; APOPTOTIC CELL DEATH; CELL SWELLING; CELL VOLUME; CHLORIDE CHANNELS; EPITHELIAL CELLS; EXTRACELLULAR; INTRACELLULAR CA; MOLECULAR IDENTITIES; PROTEIN KINASE; REGULATORY VOLUME DECREASE; VERTEBRATE CELLS;

CALCIUM; CELL DEATH; CHEMICAL ACTIVATION; CHLORINE COMPOUNDS; ENZYME ACTIVITY; PROTEINS;

CELL MEMBRANES;

ADENOSINE TRIPHOSPHATE; CALCIUM ION; CHLORIDE CHANNEL; COMPLEMENTARY DNA; MEMBRANE PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE 1; PROTEIN TMEM16; PROTEIN TMEM16A; PURINERGIC P2Y2 RECEPTOR; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ACINAR CELL; ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; AUTOCRINE EFFECT; CALCIUM CELL LEVEL; CELL PROLIFERATION; CELL SWELLING; CELL VOLUME; CHLORIDE CURRENT; COLON MUCOSA; CONTROLLED STUDY; EPITHELIUM CELL; FLUORESCENCE ACTIVATED CELL SORTING; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PATCH CLAMP; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ANIMALS; APOPTOSIS; CALCIUM; CELL LINE; CELL LINE, TUMOR; CELL SEPARATION; CHLORIDE CHANNELS; CHLORIDES; GENE EXPRESSION REGULATION; HUMANS; MEMBRANE PROTEINS; MICE; MICE, TRANSGENIC; NEOPLASM PROTEINS; PATCH-CLAMP TECHNIQUES; PROTEIN STRUCTURE, TERTIARY;

MUS; VERTEBRATA;

EID: 70350398260     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.010074     Document Type: Article

References (31)

1. Stutzin, A., and Hoffmann, E. K. (2006) Acta Physiol. (Oxf.) 187, 27-42
2. Okada, Y., Maeno, E., Shimizu, T., Manabe, K., Mori, S., and Nabekura, T. (2004) Pflugers Arch. 448, 287-295
3. Lang, F., Busch, G. L., Ritter, M., Völkl, H., Waldegger, S., Gulbins, E., and Häussinger, D. (1998) Physiol. Rev. 78, 247-306
4. Lang, F., Madlung, J., Bock, J., Lükewille, U., Kaltenbach, S., Lang, K. S., Belka, C., Wagner, C. A., Lang, H. J., Gulbins, E., and Lepple-Wienhues, A. (2000) Pflugers Arch. 440, 902-907
5. Hoffmann, E. K., Simonsen, L. O., and Lambert, I. H. (1984) J. Membr. Biol. 78, 211-222
6. Pedersen, S. F., Prenen, J., Droogmans, G., Hoffmann, E. K., and Nilius, B. (1998) J. Membr. Biol. 163, 97-110
7. Hoffmann, E. K. (2000) Cell Physiol. Biochem. 10, 273-288
8. Jentsch, T. J., Stein, V., Weinreich, F., and Zdebik, A. A. (2002) Physiol. Rev. 82, 503-568
9. Fürst, J., Gschwentner, M., Ritter, M., Bottà, G., Jakab, M., Mayer, M., Garavaglia, L., Bazzini, C., Rodighiero, S., Meyer, G., Eichmüller, S., Wöll, E., and Paulmichl, M. (2002) Pflugers Arch. 444, 1-25
10. Vennekens, R., Trouet, D., Vankeerberghen, A., Voets, T., Cuppens, H., Eggermont, J., Cassiman, J. J., Droogmans, G., and Nilius, B. (1999) J. Physiol. 515, 75-85
11. Valverde, M. A., O'Brien, J. A., Sepúlveda, F. V., Ratcliff, R., Evans, M. J., and Colledge, W. H. (1993) Pflügers Arch 425, 434-438
12. Valverde, M. A., O'Brien, J. A., Sepúlveda, F. V., Ratcliff, R. A., Evans, M. J., and Colledge, W. H. (1995) Proc. Natl. Acad. Sci. U.S.A. 92, 9038-9041
13. Katoh, M., and Katoh, M. (2004) Int. J. Mol. Med. 14, 759-764
14. Rock, J. R., Futtner, C. R., and Harfe, B. D. (2008) Dev. Biol. 321, 141-149
15. Carles, A., Millon, R., Cromer, A., Ganguli, G., Lemaire, F., Young, J., Wasylyk, C., Muller, D., Schultz, I., Rabouel, Y., Dembélé, D., Zhao, C., Marchal, P., Ducray, C., Bracco, L., Abecassis, J., Poch, O., and Wasylyk, B. (2006) Oncogene 25, 1821-1831
16. Yang, Y. D., Cho, H., Koo, J. Y., Tak, M. H., Cho, Y., Shim, W. S., Park, S. P., Lee, J., Lee, B., Kim, B. M., Raouf, R., Shin, Y. K., and Oh, U. (2008) Nature 455, 1210-1215
17. Schroeder, B. C., Cheng, T., Jan, Y. N., and Jan, L. Y. (2008) Cell 134, 1019-1029
18. Caputo, A., Caci, E., Ferrera, L., Pedemonte, N., Barsanti, C., Sondo, E., Pfeffer, U., Ravazzolo, R., Zegarra-Moran, O., and Galietta, L. J. (2008) Science 322, 590-594
19. Takizawa, P. A., DeRisi, J. L., Wilhelm, J. E., and Vale, R. D. (2000) Science 290, 341-344
20. Altamirano, J., Brodwick, M. S., and Alvarez-Leefmans, F. J. (1998) J. Gen. Physiol. 112, 145-160
21. Pafundo, D. E., Mut, P., Pérez Recalde, M., González-Lebrero, R. M., Fachino, V., Krumschnabel, G., and Schwarzbaum, P. J. (2004) Am. J. Physiol. Regul. Integr. Comp Physiol. 287, R833-R843
22. Kunzelmann, K., Allert, N., Kubitz, R., Breuer, W. V., Cabantchik, Z. I., Normann, C., Schumann, S., Leipziger, J., and Greger, R. (1994) Pflügers Arch. 428, 76-83
23. de la Fuente, R., Namkung, W., Mills, A., and Verkman, A. S. (2008) Mol. Pharmacol. 73, 758-768
24. Pifferi, S., Dibattista, M., and Menini, A. (2009) Pflugers Arch., in press
25. Franco, R., Panayiotidis, M. I., and de la Paz, L. D. (2008) J. Cell. Physiol. 216, 14-28
26. Chen, B., Nicol, G., and Cho, W. K. (2007) J. Membr. Biol. 215, 1-13
27. Van der Wijk, T., De Jonge, H. R., and Tilly, B. C. (1999) Biochem. J. 343, 579-586
28. Adam, G., Ousingsawat, J., Schreiber, R., and Kunzelmann, K. (2005) Pflügers Arch. 449, 470-478
29. Lang, F., Ritter, M., Gamper, N., Huber, S., Fillon, S., Tanneur, V., Lepple-Wienhues, A., Szabo, I., and Gulbins, E. (2000) Cell Physiol. Biochem. 10, 417-428
30. Lan, W. Z., Abbas, H., Lam, H. D., Lemay, A. M., and Hill, C. E. (2005) Am. J. Physiol. Gastrointest. Liver Physiol. 288, G221-G229
31. Diener, M., Nobles, M., and Rummel, W. (1992) Pflügers Arch. 421, 530-538