메뉴 건너뛰기




Volumn 110, Issue 48, 2013, Pages 19354-19359

Purified TMEM16A is sufficient to form Ca2+-activated Cl - channels

Author keywords

Anoctamin; Ion channels; Membrane protein; Reconstitution

Indexed keywords

CALCIUM ACTIVATED CHLORIDE CHANNEL; CALMODULIN; GLUTARALDEHYDE; LIPOSOME; PROTEIN; PROTEOLIPOSOME; TMEM16A PROTEIN; UNCLASSIFIED DRUG; VALINOMYCIN;

EID: 84888323395     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1312014110     Document Type: Article
Times cited : (94)

References (34)
  • 2
    • 79958153355 scopus 로고    scopus 로고
    • Physiological roles and diseases of Tmem16/Anoctamin proteins: Are they all chloride channels?
    • Duran C, Hartzell HC (2011) Physiological roles and diseases of Tmem16/Anoctamin proteins: Are they all chloride channels? Acta Pharmacol Sin 32(6): 685-692.
    • (2011) Acta Pharmacol Sin , vol.32 , Issue.6 , pp. 685-692
    • Duran, C.1    Hartzell, H.C.2
  • 3
    • 0020000208 scopus 로고
    • Voltage-activated and calcium-activated currents studied in solitary rod inner segments from the salamander retina
    • Bader CR, Bertrand D, Schwartz EA (1982) Voltage-activated and calcium-activated currents studied in solitary rod inner segments from the salamander retina. J Physiol 331: 253-284.
    • (1982) J Physiol , vol.331 , pp. 253-284
    • Bader, C.R.1    Bertrand, D.2    Schwartz, E.A.3
  • 4
    • 54949112835 scopus 로고    scopus 로고
    • TMEM16A, a membrane protein associated with calciumdependent chloride channel activity
    • Caputo A, et al. (2008) TMEM16A, a membrane protein associated with calciumdependent chloride channel activity. Science 322(5901): 590-594.
    • (2008) Science , vol.322 , Issue.5901 , pp. 590-594
    • Caputo, A.1
  • 5
    • 51549120559 scopus 로고    scopus 로고
    • Expression cloning of TMEM16A as a calcium-activated chloride channel subunit
    • Schroeder BC, Cheng T, Jan YN, Jan LY (2008) Expression cloning of TMEM16A as a calcium-activated chloride channel subunit. Cell 134(6): 1019-1029.
    • (2008) Cell , vol.134 , Issue.6 , pp. 1019-1029
    • Schroeder, B.C.1    Cheng, T.2    Jan, Y.N.3    Jan, L.Y.4
  • 6
    • 55249091085 scopus 로고    scopus 로고
    • TMEM16A confers receptor-activated calcium-dependent chloride conductance
    • Yang YD, et al. (2008) TMEM16A confers receptor-activated calcium-dependent chloride conductance. Nature 455(7217): 1210-1215.
    • (2008) Nature , vol.455 , Issue.7217 , pp. 1210-1215
    • Yang, Y.D.1
  • 7
    • 80355130001 scopus 로고    scopus 로고
    • 2+-activated Cl- currents in cerebral artery smooth muscle cells
    • 2+-activated Cl- currents in cerebral artery smooth muscle cells. Am J Heart Circ Physiol 301(5): H1819-H1827.
    • (2011) Am J Heart Circ Physiol , vol.301 , Issue.5
    • Thomas-Gatewood, C.1
  • 8
    • 84867067619 scopus 로고    scopus 로고
    • Calcium-activated chloride channel TMEM16A modulates mucin secretion and airway smooth muscle contraction
    • Huang F, et al. (2012) Calcium-activated chloride channel TMEM16A modulates mucin secretion and airway smooth muscle contraction. Proc Natl Acad Sci USA 109(40): 16354-16359.
    • (2012) Proc Natl Acad Sci USA , vol.109 , Issue.40 , pp. 16354-16359
    • Huang, F.1
  • 9
    • 77951183327 scopus 로고    scopus 로고
    • 2+- activated Cl- channels
    • 2+- activated Cl- channels. J Clin Invest 120(4): 1240-1252.
    • (2010) J Clin Invest , vol.120 , Issue.4 , pp. 1240-1252
    • Liu, B.1
  • 10
    • 84862896642 scopus 로고    scopus 로고
    • The calcium-activated chloride channel anoctamin 1 acts as a heat sensor in nociceptive neurons
    • Cho H, et al. (2012) The calcium-activated chloride channel anoctamin 1 acts as a heat sensor in nociceptive neurons. Nat Neurosci 15(7): 1015-1021.
    • (2012) Nat Neurosci , vol.15 , Issue.7 , pp. 1015-1021
    • Cho, H.1
  • 12
    • 84863586989 scopus 로고    scopus 로고
    • TMEM16A induces MAPK and contributes directly to tumorigenesis and cancer progression
    • Duvvuri U, et al. (2012) TMEM16A induces MAPK and contributes directly to tumorigenesis and cancer progression. Cancer Res 72(13): 3270-3281.
    • (2012) Cancer Res , vol.72 , Issue.13 , pp. 3270-3281
    • Duvvuri, U.1
  • 13
    • 84866143707 scopus 로고    scopus 로고
    • Inhibition of Ca(2+)-activated Cl(-) channel ANO1/TMEM16A expression suppresses tumor growth and invasiveness in human prostate carcinoma
    • Liu W, Lu M, Liu B, Huang Y, Wang K (2012) Inhibition of Ca(2+)-activated Cl(-) channel ANO1/TMEM16A expression suppresses tumor growth and invasiveness in human prostate carcinoma. Cancer Lett 326(1): 41-51.
    • (2012) Cancer Lett , vol.326 , Issue.1 , pp. 41-51
    • Liu, W.1    Lu, M.2    Liu, B.3    Huang, Y.4    Wang, K.5
  • 14
    • 84867872837 scopus 로고    scopus 로고
    • Inhibition of cell proliferation by a selective inhibitor of the Ca(2+)-activated Cl(-) channel Ano1
    • Mazzone A, et al. (2012) Inhibition of cell proliferation by a selective inhibitor of the Ca(2+)-activated Cl(-) channel, Ano1. Biochem Biophys Res Commun 427(2): 248-253.
    • (2012) Biochem Biophys Res Commun , vol.427 , Issue.2 , pp. 248-253
    • Mazzone, A.1
  • 15
    • 79953195560 scopus 로고    scopus 로고
    • TMEM16A(a)/anoctamin-1 shares a homodimeric architecture with CLC chloride channels
    • Fallah G, et al. (2011) TMEM16A(a)/anoctamin-1 shares a homodimeric architecture with CLC chloride channels. Mol Cell Proteomics 10(2):M110.004697.
    • (2011) Mol Cell Proteomics , vol.10 , Issue.2
    • Fallah, G.1
  • 16
    • 78651384517 scopus 로고    scopus 로고
    • 2+- activated Cl- channel Ano1/TMEM16A
    • 2+- activated Cl- channel Ano1/TMEM16A. J Biol Chem 286(2): 1381-1388.
    • (2011) J Biol Chem , vol.286 , Issue.2 , pp. 1381-1388
    • Sheridan, J.T.1
  • 17
    • 84876232419 scopus 로고    scopus 로고
    • Identification of a dimerization domain in the TMEM16A calcium-activated chloride channel (CaCC)
    • Tien J, Lee HY, Minor DLJ, Jr., Jan YN, Jan LY (2013) Identification of a dimerization domain in the TMEM16A calcium-activated chloride channel (CaCC). Proc Natl Acad Sci USA 110(16): 6352-6357.
    • (2013) Proc Natl Acad Sci USA , vol.110 , Issue.16 , pp. 6352-6357
    • Tien, J.1    Lee, H.Y.2    Minor Jr., D.L.J.3    Jan, Y.N.4    Jan, L.Y.5
  • 18
    • 84862980716 scopus 로고    scopus 로고
    • 2+-activated chloride channel stoichiometrically interacts with an ezrin-radixin-moesin network
    • 2+-activated chloride channel stoichiometrically interacts with an ezrin-radixin-moesin network. Proc Natl Acad Sci USA 109(26): 10376-10381.
    • (2012) Proc Natl Acad Sci USA , vol.109 , Issue.26 , pp. 10376-10381
    • Perez-Cornejo, P.1
  • 19
  • 20
    • 79953863174 scopus 로고    scopus 로고
    • Calmodulin-dependent activation of the epithelial calciumdependent chloride channel TMEM16A
    • Tian Y, et al. (2011) Calmodulin-dependent activation of the epithelial calciumdependent chloride channel TMEM16A. FASEB J 25(3): 1058-1068.
    • (2011) FASEB J , vol.25 , Issue.3 , pp. 1058-1068
    • Tian, Y.1
  • 21
    • 84863150267 scopus 로고    scopus 로고
    • Downregulation of TMEM16A calcium-activated chloride channel contributes to cerebrovascular remodeling during hypertension by promoting basilar smooth muscle cell proliferation
    • Wang M, et al. (2012) Downregulation of TMEM16A calcium-activated chloride channel contributes to cerebrovascular remodeling during hypertension by promoting basilar smooth muscle cell proliferation. Circulation 125(5): 697-707.
    • (2012) Circulation , vol.125 , Issue.5 , pp. 697-707
    • Wang, M.1
  • 22
    • 79957786620 scopus 로고    scopus 로고
    • Voltage- and calcium-dependent gating of TMEM16A/Ano1 chloride channels are physically coupled by the first intracellular loop
    • Xiao Q, et al. (2011) Voltage- and calcium-dependent gating of TMEM16A/Ano1 chloride channels are physically coupled by the first intracellular loop. Proc Natl Acad Sci USA 108(21): 8891-8896.
    • (2011) Proc Natl Acad Sci USA , vol.108 , Issue.21 , pp. 8891-8896
    • Xiao, Q.1
  • 23
    • 84859435658 scopus 로고    scopus 로고
    • Explaining calcium-dependent gating of anoctamin-1 chloride channels requires a revised topology
    • Yu K, Duran C, Qu Z, Cui YY, Hartzell HC (2012) Explaining calcium-dependent gating of anoctamin-1 chloride channels requires a revised topology. Circ Res 110(7): 990-999.
    • (2012) Circ Res , vol.110 , Issue.7 , pp. 990-999
    • Yu, K.1    Duran, C.2    Qu, Z.3    Cui, Y.Y.4    Hartzell, H.C.5
  • 24
    • 84871860558 scopus 로고    scopus 로고
    • 2+-activated cation channel required for lipid scrambling in platelets during blood coagulation
    • 2+-activated cation channel required for lipid scrambling in platelets during blood coagulation. Cell 151(1): 111-122.
    • (2012) Cell , vol.151 , Issue.1 , pp. 111-122
    • Yang, H.1
  • 25
    • 70450270621 scopus 로고    scopus 로고
    • Regulation of TMEM16A chloride channel properties by alternative splicing
    • Ferrera L, et al. (2009) Regulation of TMEM16A chloride channel properties by alternative splicing. J Biol Chem 284(48): 33360-33368.
    • (2009) J Biol Chem , vol.284 , Issue.48 , pp. 33360-33368
    • Ferrera, L.1
  • 26
    • 0032692857 scopus 로고    scopus 로고
    • High-level expression, functional reconstitution, and quaternary structure of a prokaryotic ClC-type chloride channel
    • Maduke M, Pheasant DJ, Miller C (1999) High-level expression, functional reconstitution, and quaternary structure of a prokaryotic ClC-type chloride channel. J Gen Physiol 114(5): 713-722.
    • (1999) J Gen Physiol , vol.114 , Issue.5 , pp. 713-722
    • Maduke, M.1    Pheasant, D.J.2    Miller, C.3
  • 27
    • 33846963817 scopus 로고    scopus 로고
    • A bacterial arginine-agmatine exchange transporter involved in extreme acid resistance
    • Fang Y, Kolmakova-Partensky L, Miller C (2007) A bacterial arginine-agmatine exchange transporter involved in extreme acid resistance. J Biol Chem 282(1): 176-182.
    • (2007) J Biol Chem , vol.282 , Issue.1 , pp. 176-182
    • Fang, Y.1    Kolmakova-Partensky, L.2    Miller, C.3
  • 28
    • 8444230519 scopus 로고    scopus 로고
    • Glutaraldehyde: Behavior in aqueous solution, reaction with proteins, and application to enzyme crosslinking
    • 798-802
    • Migneault I, Dartiguenave C, Bertrand MJ, Waldron KC (2004) Glutaraldehyde: Behavior in aqueous solution, reaction with proteins, and application to enzyme crosslinking. Biotechniques 37(5):790-796, 798-802.
    • (2004) Biotechniques , vol.37 , Issue.5 , pp. 790-796
    • Migneault, I.1    Dartiguenave, C.2    Bertrand, M.J.3    Waldron, K.C.4
  • 29
    • 33947720910 scopus 로고    scopus 로고
    • Uncoupling and turnover in a Cl-/H+ exchange transporter
    • Walden M, et al. (2007) Uncoupling and turnover in a Cl-/H+ exchange transporter. J Gen Physiol 129(4): 317-329.
    • (2007) J Gen Physiol , vol.129 , Issue.4 , pp. 317-329
    • Walden, M.1
  • 30
    • 33748310543 scopus 로고    scopus 로고
    • Uncoupling of a CLC Cl-/H+ exchange transporter by polyatomic anions
    • Nguitragool W, Miller C (2006) Uncoupling of a CLC Cl-/H+ exchange transporter by polyatomic anions. J Mol Biol 362(4): 682-690.
    • (2006) J Mol Biol , vol.362 , Issue.4 , pp. 682-690
    • Nguitragool, W.1    Miller, C.2
  • 31
    • 84884144976 scopus 로고    scopus 로고
    • 2+-dependent phospholipid scrambling by a reconstituted TMEM16 ion channel
    • 2+-dependent phospholipid scrambling by a reconstituted TMEM16 ion channel. Nat Commun 4:2367.
    • (2013) Nat Commun , vol.4 , pp. 2367
    • Malvezzi, M.1
  • 32
    • 63449116167 scopus 로고    scopus 로고
    • Functional reconstitution of purified human Hv1 H+ channels
    • Lee SY, Letts JA, MacKinnon R (2009) Functional reconstitution of purified human Hv1 H+ channels. J Mol Biol 387(5): 1055-1060.
    • (2009) J Mol Biol , vol.387 , Issue.5 , pp. 1055-1060
    • Lee, S.Y.1    Letts, J.A.2    Mackinnon, R.3
  • 33
    • 0026604888 scopus 로고
    • NPPB block of Ca++-activated Cl- currents in Xenopus oocytes
    • Wu G, Hamill OP (1992) NPPB block of Ca++-activated Cl- currents in Xenopus oocytes. Pflugers Arch 420(2): 227-229.
    • (1992) Pflugers Arch , vol.420 , Issue.2 , pp. 227-229
    • Wu, G.1    Hamill, O.P.2
  • 34
    • 0028927330 scopus 로고
    • 2+ binding to calmodulin: Proteolytic susceptibility of E31 and E87 indicates interdomain interactions
    • 2+ binding to calmodulin: Proteolytic susceptibility of E31 and E87 indicates interdomain interactions. Biochemistry 34(4): 1179-1196.
    • (1995) Biochemistry , vol.34 , Issue.4 , pp. 1179-1196
    • Pedigo, S.1    Shea, M.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.