TMEM16A induces MAPK and contributes directly to tumorigenesis and cancer progression

Cancer Research

Volumn 72, Issue 13, 2012, Pages 3270-3281

  Duvvuri, Umamaheswar ^a,c   Shiwarski, Daniel J ^a   Xiao, Dong ^a   Bertrand, Carol ^a   Huang, Xin ^b   Edinger, Robert S ^a   Rock, Jason R ^e,h   Harfe, Brian D ^f   Henson, Brian J ^c,d   Kunzelmann, Karl ^g   Schreiber, Rainer ^g   Seethala, Raja S ^a   Egloff, Ann Marie ^a   Chen, Xing ^a   Lui, Vivian W ^a   Grandis, Jennifer R ^a,b   Gollin, Susanne M ^a,c,d  

^a UNIVERSITY OF PITTSBURGH MEDICAL CENTER   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF PITTSBURGH GRADUATE SCHOOL OF PUBLIC HEALTH   (United States)

^d UNIVERSITY OF PITTSBURGH CANCER INSTITUTE   (United States)

^e DUKE UNIVERSITY MEDICAL CENTER   (United States)

^f UNIVERSITY OF FLORIDA   (United States)

^g UNIVERSITY OF REGENSBURG   (Germany)

^h UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHLORIDE CHANNEL; CHLORIDE CHANNEL BLOCKING AGENT; CYCLIN D1; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN TMEM16A; SMALL INTERFERING RNA; T16A INH01; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER CELL; CANCER GROWTH; CANCER INHIBITION; CARCINOGENESIS; CELL PROLIFERATION; CELL STRAIN HEK293; CELL VIABILITY; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INDUCTION; ENZYME PHOSPHORYLATION; GENETIC TRANSFECTION; HEAD AND NECK SQUAMOUS CELL CARCINOMA; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; OVERALL SURVIVAL; PATCH CLAMP; PLASMID; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INDUCTION;

ANIMALS; CARCINOMA, SQUAMOUS CELL; CELL DIVISION; CELL LINE; CELL TRANSFORMATION, NEOPLASTIC; CHLORIDE CHANNELS; DISEASE PROGRESSION; ENZYME ACTIVATION; ENZYME INDUCTION; HEAD AND NECK NEOPLASMS; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; MICE; MICE, KNOCKOUT; MITOGEN-ACTIVATED PROTEIN KINASES; NEOPLASM PROTEINS; PHOSPHORYLATION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 84863586989     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-12-0475-T     Document Type: Article

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