ANOs 3-7 in the anoctamin/Tmem16 Cl - channel family are intracellular proteins

American Journal of Physiology - Cell Physiology

Volumn 302, Issue 3, 2012, Pages

  Duran, Charity ^a   Qu, Zhiqiang ^a   Osunkoya, Adeboye O ^a   Cui, Yuanyuan ^a   Criss Hartzell, H ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Anion transport; Calcium activated chloride channels; Chloride channels

Indexed keywords

ANOCTAMIN; ANOCTAMIN 1; ANOCTAMIN 2; ANOCTAMIN 7; CALCIUM ACTIVATED CHLORIDE CHANNEL; CALCIUM ION; CELL PROTEIN; CHLORIDE CHANNEL; PLASMA MEMBRANE CALCIUM TRANSPORTING ADENOSINE TRIPHOSPHATASE; UNCLASSIFIED DRUG;

ANION TRANSPORT; ARTICLE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; FLUID TRANSPORT; HUMAN; HUMAN CELL; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROSTATE; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN TRANSPORT;

ANIMALS; BIOLOGICAL TRANSPORT; CELL LINE; CELL MEMBRANE; CERCOPITHECUS AETHIOPS; CHIMERA; CHLORIDE CHANNELS; COS CELLS; ENDOPLASMIC RETICULUM; HEK293 CELLS; HUMANS; MALE; MEMBRANE PROTEINS; NEOPLASM PROTEINS; PATCH-CLAMP TECHNIQUES; PROSTATE; RECOMBINANT FUSION PROTEINS;

EID: 84856292939     PISSN: 03636143     EISSN: 15221563     Source Type: Journal    
DOI: 10.1152/ajpcell.00140.2011     Document Type: Article

References (42)

1. Accardi A, Picollo A. CLC channels and transporters: proteins with borderline personalities. Biochim Biophys Acta 1798: 1457-1464, 2010.
2. Bolduc V, Marlow G, Boycott KM, Saleki K, Inoue H, Kroon J, Itakura M, Robitaille Y, Parent L, Baas F, Mizuta K, Kamata N, Richard I, Linssen WH, Mahjneh I, de Visser M, Bashir R, Brais B. Recessive mutations in the putative calcium-activated chloride channel Anoctamin 5 cause proximal LGMD2L and distal MMD3 muscular dystrophies. Am J Hum Genet 86: 213-221, 2010.
3. Brambillasca S, Yabal M, Makarow M, Borgese N. Unassisted translocation of large polypeptide domains across phospholipid bilayers. J Cell Biol 175: 767-777, 2006.
4. Caputo A, Caci E, Ferrera L, Pedemonte N, Barsanti C, Sondo E, Pfeffer U, Ravazzolo R, Zegarra-Moran O, Galietta LJ. TMEM16A, a membrane protein associated with calcium-dependent chloride channel activity. Science 322: 590-594, 2008.
5. Das S, Hahn Y, Nagata S, Willingham MC, Bera TK, Lee B, Pastan I. NGEP, a prostate-specific plasma membrane protein that promotes the association of LNCaP cells. Cancer Res 67: 1594-1601, 2007.
6. Das S, Hahn Y, Walker DA, Nagata S, Willingham MC, Peehl DM, Bera TK, Lee B, Pastan I. Topology of NGEP, a prostate-specific cell:cell junction protein widely expressed in many cancers of different grade level. Cancer Res 68: 6306-6312, 2008.
7. -channel activated by extracellular nucleotides, in biliary epithelium. J Biol Chem 286: 766-776, 2011.
8. Egelman EH. Reducing irreducible complexity: divergence of quaternary structure and function in macromolecular assemblies. Curr Opin Cell Biol 22: 68-74, 2010.
9. Eggermont J. Calcium-activated chloride channels: (un)known, (un)loved? Proc Am Thorac Soc 1: 22-27, 2004.
10. Ferrera L, Caputo A, Ubby I, Bussani E, Zegarra-Moran O, Ravazzolo R, Pagani F, Galietta LJ. Regulation of TMEM16A chloride channel properties by alternative splicing. J Biol Chem 284: 33360-33368, 2009.
11. 2+-activated Cl-channels. J Physiol 587: 2127- 2139, 2009.
12. Hicks D, Sarkozy A, Muelas N, Koehler K, Huebner A, Hudson G, Chinnery PF, Barresi R, Eagle M, Polvikoski T, Bailey G, Miller J, Radunovic A, Hughes PJ, Roberts R, Krause S, Walter MC, Laval SH, Straub V, Lochmuller H, Bushby K. A founder mutation in Anoctamin 5 is a major cause of limb-girdle muscular dystrophy. Brain 134: 171-182, 2011.
13. Horton RM, Hunt HD, Ho SN, Pullen JK, Pease LR. Engineering hybrid genes without the use of restriction enzymes: gene splicing by overlap extension. Gene 77: 61-68, 1989.
14. Huang F, Rock JR, Harfe BD, Cheng T, Huang X, Jan YN, Jan LY. Studies on expression and function of the TMEM16A calciumactivated chloride channel. Proc Natl Acad Sci USA 106: 21413-21418, 2009.
15. Kiessling A, Weigle B, Fuessel S, Ebner R, Meye A, Rieger MA, Schmitz M, Temme A, Bachmann M, Wirth MP, Rieber EP. D-TMPP: a novel androgen-regulated gene preferentially expressed in prostate and prostate cancer that is the first characterized member of an eukaryotic gene family. Prostate 64: 387-400, 2005.
16. Kuruma A, Hartzell HC. Bimodal control of a Ca(2+)-activated Cl(-) channel by different Ca(2+) signals. J Gen Physiol 115: 59-80, 2000.
17. Mahjneh I, Jaiswal J, Lamminen A, Somer M, Marlow G, Kiuru-Enari S, Bashir R. A new distal myopathy with mutation in anoctamin 5. Neuromuscul Disord 20: 791-795, 2010.
18. Manoury B, Tamuleviciute A, Tammaro P. TMEM16A/anoctamin 1 protein mediates calcium-activated chloride currents in pulmonary arterial smooth muscle cells. J Physiol 588: 2305-2314, 2010.
19. Matsuda K, Miura E, Miyazaki T, Kakegawa W, Emi K, Narumi S, Fukazawa Y, Ito-Ishida A, Kondo T, Shigemoto R, Watanabe M, Yuzaki M. Cbln1 is a ligand for an orphan glutamate receptor delta2, a bidirectional synapse organizer. Science 328: 363-368, 2010.
20. Milenkovic VM, Brockmann M, Stohr H, Weber BH, Strauss O. Evolution and functional divergence of the anoctamin family of membrane proteins. BMC Evol Biol 10: 319, 2010.
21. Mizuta K, Tsutsumi S, Inoue H, Sakamoto Y, Miyatake K, Miyawaki K, Noji S, Kamata N, Itakura M. Molecular characterization of GDD1/ TMEM16E, the gene product responsible for autosomal dominant gnathodiaphyseal dysplasia. Biochem Biophys Res Commun 357: 126-132, 2007.
22. Mobasheri A, Oukrif D, Dawodu SP, Sinha M, Greenwell P, Stewart D, Djamgoz MB, Foster CS, Martin-Vasallo P, Mobasheri R. Isoforms of Na+, K+-ATPase in human prostate; specificity of expression and apical membrane polarization. Histol Histopathol 16: 141-154, 2001.
23. Mobasheri A, Pestov NB, Papanicolaou S, Kajee R, Cozar-Castellano I, Avila J, Martin-Vasallo P, Foster CS, Modyanov NN, Djamgoz MB. Expression and cellular localization of Na,K-ATPase isoforms in the rat ventral prostate. BJU Int 92: 793-802, 2003.
24. Munro S, Pelham HR. A C-terminal signal prevents secretion of luminal ER proteins. Cell 48: 899-907, 1987.
25. Namkung W, Phuan PW, Verkman AS. TMEM16A inhibitors reveal TMEM16A as a minor component of CaCC conductance in airway and intestinal epithelial cells. J Biol Chem 286: 2365-2374, 2011.
26. 2+-dependent chloride transport. J Biol Chem 284: 28698-28703, 2009.
27. Pestov NB, Korneenko TV, Adams G, Tillekeratne M, Shakhparonov MI, Modyanov NN. Nongastric H-K-ATPase in rodent prostate: lobespecific expression and apical localization. Am J Physiol Cell Physiol 282: C907-C916, 2002.
28. Pifferi S, Dibattista M, Menini A. TMEM16B induces chloride currents activated by calcium in mammalian cells. Pflügers Arch 458: 1023-1038, 2009.
29. Rasche S, Toetter B, Adler J, Tschapek A, Doerner JF, Kurtenbach S, Hatt H, Meyer H, Warscheid B, Neuhaus EM. Tmem16b is specifically expressed in the cilia of olfactory sensory neurons. Chem Senses 35: 239-245, 2010.
30. 2+-activated Cl-channel in mouse submandibular salivary gland acinar cells. J Biol Chem 285: 12990-13001, 2010.
31. Ronchi P, Colombo S, Francolini M, Borgese N. Transmembrane domain-dependent partitioning of membrane proteins within the endoplasmic reticulum. J Cell Biol 181: 105-118, 2008.
32. Sagheddu C, Boccaccio A, Dibattista M, Montani G, Tirindelli R, Menini A. Calcium concentration jumps reveal dynamic ion selectivity of calcium-activated chloride currents in mouse olfactory sensory neurons and TMEM16b-transfected HEK 293T cells. J Physiol 588: 4189-4204, 2010.
33. 2+ channels in fish skeletal muscle excitation-contraction coupling. Proc Natl Acad Sci USA 107: 5658-5663, 2010.
34. Schreiber R, Uliyakina I, Kongsuphol P, Warth R, Mirza M, Martins JR, Kunzelmann K. Expression and function of epithelial anoctamins. J Biol Chem 285: 7838-7845, 2010.
35. Schroeder BC, Cheng T, Jan YN, Jan LY. Expression cloning of TMEM16A as a calcium-activated chloride channel subunit. Cell 134: 1019-1029, 2008.
36. Shen H, Chou JJ. MemBrain: improving the accuracy of predicting transmembrane helices. PLos One 3: e2399, 2008.
37. Stephan AB, Shum EY, Hirsh S, Cygnar KD, Reisert J, Zhao H. ANO2 is the cilial calcium-activated chloride channel that may mediate olfactory amplification. Proc Natl Acad Sci USA 106: 11776-11781, 2009.
38. Stohr H, Heisig JB, Benz PM, Schoberl S, Milenkovic VM, Strauss O, Aartsen WM, Wijnholds J, Weber BH, Schulz HL. TMEM16B, a novel protein with calcium-dependent chloride channel activity, associates with a presynaptic protein complex in photoreceptor terminals. J Neurosci 29: 6809-6818, 2009.
39. Tsutsumi S, Inoue H, Sakamoto Y, Mizuta K, Kamata N, Itakura M. Molecular cloning and characterization of the murine gnathodiaphyseal dysplasia gene GDD1. Biochem Biophys Res Commun 331: 1099-1106, 2005.
40. Tsutsumi S, Kamata N, Vokes TJ, Maruoka Y, Nakakuki K, Enomoto S, Omura K, Amagasa T, Nagayama M, Saito-Ohara F, Inazawa J, Moritani M, Yamaoka T, Inoue H, Itakura M. The novel gene encoding a putative transmembrane protein is mutated in gnathodiaphyseal dysplasia (GDD). Am J Hum Genet 74: 1255-1261, 2004.
41. Xiao Q, Yu K, Perez-Cornejo P, Cui Y, Arreola J, Hartzell HC. Voltage-and calcium-dependent gating of TMEM16A/Ano1 chloride channels are physically coupled by the first intracellular loop. Proc Natl Acad Sci USA 108: 8891-8896, 2011.
42. Yang YD, Cho H, Koo JY, Tak MH, Cho Y, Shim WS, Park SP, Lee J, Lee B, Kim BM, Raouf R, Shin YK, Oh U. TMEM16A confers receptor-activated calcium-dependent chloride conductance. Nature 455: 1210-1215, 2008.