Anoctamin 1 induces calcium-activated chloride secretion and proliferation of renal cyst-forming epithelial cells

Kidney International

Volumn 85, Issue 5, 2014, Pages 1058-1067

  Buchholz, Bjoern ^a   Faria, Diana ^b   Schley, Gunnar ^a   Schreiber, Rainer ^b   Eckardt, Kai Uwe ^a   Kunzelmann, Karl ^b  

^a UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^b UNIVERSITY OF REGENSBURG   (Germany)

Author keywords

ADPKD; Calcium; Cyclic AMP; Ion channel; Polycystic kidney disease; Renal tubular epithelial cells

Indexed keywords

ANOCTAMIN 1; ANOCTAMIN 6; CALCIUM; CALCIUM ACTIVATED CHLORIDE CHANNEL; CHLORIDE CHANNEL BLOCKING AGENT; COLLAGEN; TANNIN; UNCLASSIFIED DRUG; AGENTS AFFECTING WATER, MOLECULE OR ION TRANSPORT; ANO1 PROTEIN, HUMAN; CHLORIDE; CHLORIDE CHANNEL; PURINERGIC RECEPTOR STIMULATING AGENT; TMEM16A PROTEIN, MOUSE; TUMOR PROTEIN;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTOSOMAL DOMINANT DISORDER; CALCIUM DEPENDENT CHLORIDE SECRETION; CELL PROLIFERATION; CELLULAR SECRETION; CHLORIDE TRANSPORT; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE ACTIVITY; DISEASE COURSE; DISEASE MODEL; EMBRYO; EPITHELIUM CELL; FEMALE; GENE SILENCING; HUMAN; HUMAN TISSUE; KIDNEY CYST; KIDNEY POLYCYSTIC DISEASE; MALE; MDCK CELL LINE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; ANIMAL; ANTAGONISTS AND INHIBITORS; C57BL MOUSE; DOG; DRUG EFFECTS; EMBRYOLOGY; GENETIC TRANSFECTION; GENETICS; KIDNEY; METABOLISM; MIDDLE AGED; ORGAN CULTURE TECHNIQUE; PATHOLOGY; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TIME;

ANIMALS; CELL PROLIFERATION; CHLORIDE CHANNELS; CHLORIDES; DISEASE PROGRESSION; DOGS; EPITHELIAL CELLS; FEMALE; HUMANS; KIDNEY; MADIN DARBY CANINE KIDNEY CELLS; MALE; MEMBRANE TRANSPORT MODULATORS; MICE, INBRED C57BL; MIDDLE AGED; NEOPLASM PROTEINS; ORGAN CULTURE TECHNIQUES; POLYCYSTIC KIDNEY, AUTOSOMAL DOMINANT; PURINERGIC AGONISTS; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TIME FACTORS; TRANSFECTION;

EID: 84899750733     PISSN: 00852538     EISSN: 15231755     Source Type: Journal    
DOI: 10.1038/ki.2013.418     Document Type: Article

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