Thiazolidinone CFTR inhibitor identified by high-throughput screening blocks cholera toxin-induced intestinal fluid secretion

Journal of Clinical Investigation

Volumn 110, Issue 11, 2002, Pages 1651-1658

  Ma, Tonghui ^a   Thiagarajah, Jay R ^a   Yang, Hong ^a   Sonawane, Nitin D ^a   Folli, Chiara ^b   Galietta, Luis J V ^b   Verkman, A S ^a,c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b G GASLINI INSTITUTE   (Italy)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; CHOLERA TOXIN; CYCLIC AMP; FLAVONE; MULTIDRUG RESISTANCE PROTEIN 1; POTASSIUM CHANNEL; POTASSIUM ION; PROTEIN INHIBITOR; THIAZOLIDINONE INHIBITOR; TRANSMEMBRANE CONDUCTANCE REGULATOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL TRANSPORT; CHEMICAL STRUCTURE; CHOLERA; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CYSTIC FIBROSIS; DEHYDRATION; DIARRHEA; DISEASE MODEL; DRUG POTENCY; ELECTRIC POTENTIAL; EPITHELIUM CELL; HUMAN; HUMAN CELL; INTESTINE SECRETION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SCREENING; SMALL INTESTINE; TIME;

EID: 0036896008     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI0216112     Document Type: Article

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