TMEM16A inhibitors reveal TMEM16A as a minor component of calcium-activated chloride channel conductance in airway and intestinal epithelial cells

Journal of Biological Chemistry

Volumn 286, Issue 3, 2011, Pages 2365-2374

  Namkung, Wan ^a   Phuan, Puay Wah ^a   Verkman, A S ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM SIGNALING; CHEMICAL CLASS; CHLORIDE CHANNELS; HUMAN AIRWAY; INTESTINAL CELLS; INTESTINAL EPITHELIAL CELLS; MINOR COMPONENTS; POTENT INHIBITOR; SALIVARY GLANDS; SMALL MOLECULE INHIBITOR; SMALL MOLECULES; STRUCTURE-ACTIVITY; TANNIC ACID;

CALCIUM; CELLS; CHEMICAL COMPOUNDS; DRUG THERAPY;

CHLORINE COMPOUNDS;

AMINOPHENYLTHIAZOLE; ARYLAMINOTHIOPENE; CALCIUM ACTIVATED CHLORIDE CHANNEL; CHLORIDE CHANNEL; DIGALLIC ACID; ION TRANSPORT AFFECTING AGENT; PROTEIN TMEM16A; TANNIN; UNCLASSIFIED DRUG;

ARTICLE; CALCIUM SIGNALING; CHLORIDE CONDUCTANCE; CHLORIDE CURRENT; CONTROLLED STUDY; HUMAN; HUMAN CELL; IC 50; INTESTINE EPITHELIUM CELL; PRIORITY JOURNAL; PROTEIN FUNCTION; RESPIRATORY EPITHELIUM; RNA INTERFERENCE; SALIVARY GLAND; STRUCTURE ACTIVITY RELATION;

CELL LINE; CHLORIDE CHANNELS; CHLORIDES; DIARRHEA; DRUG EVALUATION, PRECLINICAL; EPITHELIAL CELLS; HUMANS; HYPERTENSION; INTESTINAL MUCOSA; ION TRANSPORT; MEMBRANE PROTEINS; MEMBRANE TRANSPORT MODULATORS; NEOPLASM PROTEINS; PAIN; RESPIRATORY MUCOSA; SALIVARY GLANDS;

EID: 78751478642     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.175109     Document Type: Article

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