Cell death caused by quinazolinone HMJ-38 challenge in oral carcinoma CAL 27 cells: Dissections of endoplasmic reticulum stress, mitochondrial dysfunction and tumor xenografts

Biochimica et Biophysica Acta - General Subjects

Volumn 1840, Issue 7, 2014, Pages 2310-2320

  Lu, Chi Cheng ^a   Yang, Jai Sing ^b   Chiang, Jo Hua ^a   Hour, Mann Jen ^b   Lin, Kuei Li ^c   Lee, Tsung Han ^a,b   Chung, Jing Gung ^b,d  

^a NATIONAL CHUNG HSING UNIVERSITY   (Taiwan)

^b CHINA MEDICAL UNIVERSITY   (Taiwan)

^c CHI MEI MEDICAL CENTER   (Taiwan)

^d ASIA UNIVERSITY   (Taiwan)

Author keywords

Endoplasmic reticulum stress; HMJ 38; Human oral carcinoma cells; Mitochondrial dysfunction; Tumor xenografts

Indexed keywords

2 (3' METHOXYPHENYL) 6 PYRROLIDINYL 4 QUINAZOLINONE; CALCIUM ION; CASPASE 3; CASPASE 9; CYCLIN DEPENDENT KINASE 1; DNA; HMJ 38; MITOCHONDRIAL PERMEABILITY TRANSITION PORE; PROTEIN BCL 2; QUINAZOLINONE DERIVATIVE; SERINE; UNCLASSIFIED DRUG;

AGAR GEL ELECTROPHORESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CAL 27 CELL LINE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CANCER CELL LINE; CANCER INHIBITION; CELL DEATH; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DNA FRAGMENTATION; DRUG CYTOTOXICITY; DRUG DOSE COMPARISON; DRUG EFFICACY; DRUG STRUCTURE; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVATION; FLOW CYTOMETRY; G2 PHASE CELL CYCLE CHECKPOINT; GENE EXPRESSION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IN VITRO STUDY; IN VIVO STUDY; MALE; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOSIS INHIBITION; MOUSE; MOUTH SQUAMOUS CELL CARCINOMA; MTT ASSAY; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TREATMENT DURATION; TUMOR VOLUME; TUMOR XENOGRAFT; UNFOLDED PROTEIN RESPONSE; XENOTRANSPLANTATION;

ENDOPLASMIC RETICULUM STRESS; HMJ-38; HUMAN ORAL CARCINOMA CELLS; MITOCHONDRIAL DYSFUNCTION; TUMOR XENOGRAFTS;

ANIMALS; CARCINOMA; CELL DEATH; CELL LINE, TUMOR; CELL SURVIVAL; ENDOPLASMIC RETICULUM STRESS; HETEROGRAFTS; HUMANS; MICE; MITOCHONDRIA; MOUTH NEOPLASMS; QUINAZOLINONES; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION;

EID: 84899793813     PISSN: 03044165     EISSN: 18728006     Source Type: Journal    
DOI: 10.1016/j.bbagen.2014.02.022     Document Type: Article

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