Trichodermin induces cell apoptosis through mitochondrial dysfunction and endoplasmic reticulum stress in human chondrosarcoma cells

Toxicology and Applied Pharmacology

Volumn 272, Issue 2, 2013, Pages 335-344

  Su, Chen Ming ^a   Wang, Shih Wei ^b   Lee, Tzong Huei ^c   Tzeng, Wen Pei ^d   Hsiao, Che Jen ^e   Liu, Shih Chia ^f   Tang, Chih Hsin ^a,g,h  

^a CHINA MEDICAL UNIVERSITY   (Taiwan)

^b MACKAY MEDICAL COLLEGE   (Taiwan)

^c TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^d NATIONAL CHANGHUA UNIVERSITY OF EDUCATION   (Taiwan)

^e TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^f MACKAY MEMORIAL HOSPITAL   (Taiwan)

^g CHINA MEDICAL UNIVERSITY   (Taiwan)

^h ASIA UNIVERSITY   (Taiwan)

Author keywords

Apoptosis; Chondrosarcoma; Endoplasmic reticulum (ER) stress; Mitochondrial dysfunction; Trichodermin

Indexed keywords

CASPASE 3; CYTOCHROME C; DNA NUCLEOTIDYLEXOTRANSFERASE; GLUCOSE REGULATED PROTEIN 78; GLUCOSE REGULATED PROTEIN 94; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BID; PROTEIN IRE1; TRICHODERMIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BALB/C NUDE MOUSE; CARTILAGE CELL; CHONDROSARCOMA; CONTROLLED STUDY; DRUG EFFECT; ENDOPLASMIC RETICULUM STRESS; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; NICK END LABELING; NONHUMAN; RANDOMIZED CONTROLLED TRIAL; TUMOR CELL; TUMOR VOLUME; TUMOR XENOGRAFT; UPREGULATION;

APOPTOSIS; CHONDROSARCOMA; ENDOPLASMIC RETICULUM (ER) STRESS; MITOCHONDRIAL DYSFUNCTION; TRICHODERMIN;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; BONE NEOPLASMS; CALCIUM; CELL CULTURE TECHNIQUES; CELL LINE, TUMOR; CELL SURVIVAL; CHONDROSARCOMA; ENDOPLASMIC RETICULUM STRESS; HUMANS; MALE; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICE; MICE, NUDE; MITOCHONDRIA; TRICHODERMIN; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84883794521     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2013.06.010     Document Type: Article

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